Digital Commons Network^™

A Comparative Evaluation Of The Effects Of Social Skills Group Training And Computer- Based Social Skills Training, Indira Hightower

Theses and Dissertations

This applied dissertation was designed to evaluate the effects of social skills training programs as a method to improve social skills in children diagnosed with autism spectrum disorder. The study sought to advance the social skills training options for children with autism spectrum disorder by comparing various evidence-based social skills training programs in hope to provide meaningful, significant, and sustainable social-emotional changes that are explicitly taught and later generalized across individuals, settings, and environments. The researcher specifically evaluated the effects of social skills group training and computer-based social skills training among the three study participants with autism spectrum disorder.

The …

Teacher Perceptions Of Classroom Management Programs To Improve Whole-School Measures Of Attendance, Disruptive Classroom Behaviors, And Academic Outcomes, Charles E. Natt, Jr

Theses and Dissertations

This qualitative case study explored how the implementation of Capturing Kids’ Hearts (CKH) and Multi-Tiered System of Supports (MTSS) classroom management programs when implemented together affected students and teachers of a Louisiana K-12 school compared with using the Positive Behavior Interventions and Supports (PBIS) program alone. Teachers at the school who had used the PBIS alone and then also used the newly implanted CKH and MTSS programs participated in in-depth interviews to examine the practical effectiveness of both program implementations upon students and classroom learning effectiveness. Teacher perceptions were also compared with ex post facto data for the school from …

Examining Ayahuasca Constituents At 5-Ht2a Receptors In Search Of Antidepressant Action, Jeremy D. Rolquin

Theses and Dissertations

Recently, it has been reported that ligands of the 5-HT_2A receptor can have drastic and fast-acting efficacy towards a number of different mental health disorders, such as depression and anxiety. A mixture of Amazonian plants calledayahuasca contains multiple compounds which have been shown to interact with the serotonergic system, and the 5-HT_2Areceptor in particular.

The structurally similar compounds (DMT, harmine, harmaline, and tetrahydroharmine) found in ayahuasca were examined for differences in their physiochemical properties that might contribute to their binding affinity for the 5-HT_2Areceptor. 3D Molecular modeling and docking studies of these compounds were …

The Role Of Human Dopamine Transporter Threonine 261 And Serine 262 In Amphetamine Regulation Of Transporter Function And Surface Expression, Sina Abdollahi

Theses and Dissertations

Amphetamine (AMPH) has been used clinically and recreationally around the world for years. A 2021 study reports a 67.5% rise in AMPH use from 2010-2017 across all fifty states. Study also shows that 30% of patients with AMPH-induced psychosis end up with primary psychosis over time. AMPH works by inhibiting monoamine (Norepinephrine (NE), Serotonin (5-HT), and Dopamine (DA) reuptake followed by triggering transporter mediated monoamine release and consequently increases monoamine concentrations in extracellular synaptic space. AMPH also works as a substrate for monoamine transporters, enters the neuron, and once its inside the neuron, it will prevent the storage of monoamines …

Dregs / Lessons From The Things Around Us, Juan-Manuel Pinzon

Theses and Dissertations

The writing in Lessons From the Things Around Us is in support of the work in my MFA thesis show, dregs. I detail the progression of my making and thinking over the last two years. I expand on the material and personal relationships that have manifested themselves in the work and influenced my approach to the things that surround me. Finally, I point to a more expansive definition of Craft, rooted in its material sensibilities, and the possibilities already present in the field that this definition creates.

Innovative Techniques Of Neuromodulation And Neuromodeling Based On Focal Non-Invasive Transcranial Magnetic Stimulation For Neurological Disorders, Ivan C. Carmona-Tortolero

Theses and Dissertations

This dissertation aims to develop alternative technology that improves the current range of application of transcranial magnetic stimulation (TMS), on a scale that would permit defining specific non-invasive treatments for Parkinson’s disease and other neurological disorders. This is accomplished through three specific objectives. 1) The design of a neurostimulation system that increases the focality in TMS to regions of narrow target areas and variable depths in the brain cortex. 2) The assessment of the feasibility of novel high-frequency neuromodulation techniques that would allow increasing the focality in deeper areas beyond the cortical surface. 3) The development of a computational model …

Investigating The Role Of Nlrp3 Inflammasome In Chemotherapy-Induced Peripheral Neuropathy, Urszula O. Warncke

Theses and Dissertations

Paclitaxel and oxaliplatin are commonly used antineoplastic drugs that cause chemotherapy-induce peripheral neuropathy (CIPN) in up to 90% of patients. The sensory symptoms of CIPN include numbness, loss of proprioception, tingling, spontaneous burning, shooting or electric shock-like pain, mechanical and thermal allodynia, and cold hypersensitivity among others. Affected patients struggle with daily activities, have a low quality of life, and might stop cancer treatment. Unfortunately, there are no effective prophylactic or therapeutic treatments for these side effects. Many studies point to the involvement of inflammation as a major contributor of CIPN pathology. We investigated the effects of genetic (NLRP3 …

Health Risk Perceptions Regarding Electronic Nicotine Delivery Systems (Ends) Among Individuals With Respiratory Illnes, Sarah Ann Sebban

Theses and Dissertations

Electronic nicotine delivery systems (ENDS), also known as electronic cigarettes, are portable battery-powered devices used to smoke or “vape” a flavored solution which usually contains nicotine. Many national organizations (CDC, AMA, AAFP, ALA, AHA) have recognized the alarmingly increased rates of ENDS use in the United States, especially among certain populations. Those most likely to engage in ENDS use are youth and young adults, and adults who already smoke combustible cigarettes. Many people perceive ENDS use as a healthier alternative to smoking regular cigarettes and thus, are more willing to initiate ENDS use. However, research has indicated that ENDS use …

She: Performing Biography As A Dramatic Narrative, Ashley J. Love

Theses and Dissertations

Abstract

SHE: PERFORMING BIOGRAPHY AS DRAMATIC NARRATIVE

By Ashley Love, Master of Fine Arts at Virginia Commonwealth University

Partial Fulfillment Statement:

Thesis submitted in partial fulfillment of the requirement for a Master of Fine Arts in Theatre Pedagogy at Virginia Commonwealth University.

Director: Dr. Aaron Anderson

Interim Director of Graduate Studies, Theatre Department

Amid the current wave of feminism, women continue to strive for equal ground within societal constructs. Progress is being made in the workplace, the arts, and media presence, but why does it seem that women’s stories of the past continue to be overlooked as if insignificant? This …

Role Of Aurora Kinase A, Rab4a, And Endolysosomes In The Development Of Alzheimer’S Disease-Like Pathology, Zahra Afghah

Theses and Dissertations

Endosomes and lysosomes (endolysosomes) are organelles that play key roles in cell survival and cell death. These acidic intracellular organelles are the principal sites for intracellular hydrolytic activity required for the maintenance of cellular homeostasis. Endolysosomes are involved in the degradation of plasma membrane components, extracellular macromolecules, as well as intracellular macromolecules and cellular fragments. Understanding the physiological significance and pathological relevance of endolysosomes is now complicated by relatively recent findings of physical and functional interactions between endolysosomes and other intracellular organelles including endoplasmic reticulum, mitochondria, plasma membranes, and peroxisomes. Indeed, evidence clearly indicates that endolysosome dysfunction and inter-organellar signaling …

The Experience Of Saudi Students Writing Academic English In Sex-Separated Classrooms, Rana Alsaadi

Theses and Dissertations

This is a qualitative research that investigates the experiences of undergraduate Saudi female and male students majoring in English at Taif University, Saudi Arabia. These students were part of different sections of a course that teaches academic English writing and research in an English as a Foreign Language context. These Saudi female and male students draw on their perceptions of three main points; First, how they experienced the academic English writing course in sex-separated classrooms. Second, how the current sex-separated classrooms influence their learning of English and how if this hypothetically change to mixed-sex classrooms their experiences in learning English …

The Discovery And Investigation Of Jig (Cg14850): A Previously Uncharacterized Novel Drosophila Melanogaster Protein, Sayem Hoque Bhuiyan

Theses and Dissertations

Despite Drosophila being one of the most studied model organisms in the world of research, one-third of 14,000 protein-encoding genes that the Drosophila genome possesses code for proteins that are yet uncharacterized. While investigating some of these uncharacterized Drosophila proteins, we identified a scarce protein type–a protein localized in both mitochondria and nucleus. Proteins, dual-localized in mitochondria and nucleus, establish communication between these organelles. This type of dual-localized protein is among the rarest of proteins, which limits us from fully understanding the mito-nuclear communication mechanism. Here, we tell the story of Jig, which we discovered to be one of those …

The Architecture And Dynamics Of Gene Regulatory Networks Directing Cell-Fate Choice During Murine Hematopoiesis, Joanna Handzlik

Theses and Dissertations

Mammals produce hundreds of billions of new blood cells every day througha process known as hematopoiesis. Hematopoiesis starts with stem cells that develop into all the different types of cells found in blood by changing their genome-wide gene expression. The remodeling of genome-wide gene expression can be primarily attributed to a special class of proteins called transcription factors (TFs) that can activate or repress other genes, including genes encoding TFs. TFs and their targets therefore form recurrent networks called gene regulatory networks (GRNs). GRNs are crucial during physiological developmental processes, such as hematopoiesis, while abnormalities in the regulatory interactions of …

Suitability Analysis Of Snow And Ice Changes For Ice Patch Archaeology: A Case Study In The Crazy Mountains, Montana, Christine Kay Lidenberg

Theses and Dissertations

As technology advances over the years there has been a growing interest in the application of using remote sensing for conveying the detection of alpine archaeological sites. As climate changes and global temperatures rise across the globe perennial snow/ ice patches are melting and disappearing in alpine areas. These alpine archaeological sites are being immensely affected and, in some cases, destroyed. The research was conducted to determine if using both remote sensing imagery and suitability models could detect the extent of perennial snow/ice patch loss and determine the ice patches most vulnerable to melting in the Crazy Mountains of Montana. …

Landscape Ecology Influence On Population Dynamics And Gene Flow: A Muskrat’S Tale, Ayla A. Morehouse

Theses and Dissertations

Understanding movement patterns across a landscape is an essential tool for wildlife managers to understand and predict population dynamics, interactions, and susceptibility to disease and environmental changes. Part of this is due to population spatial synchrony being driven by three primary factors: dispersal, the “Moran Effect”, and trophic interactions. We seek to understand if dispersal may play a larger role in population synchrony and, if so, what landscape features may hinder the movement of muskrats (Ondatra zibethicus), a small semiaquatic mammal that relies on ditches and shallow wetlands for habitat and local movement. In this study we genotyped eleven microsatellite …

Mosquito Fauna And Prevalence Of Avian Malaria In The Turtle Mountains, North Dakota, Kelsey J. Morin

Theses and Dissertations

Avian malaria is a disease caused by intracellular parasites transmitted by mosquitoes and is detrimental to individual birds and their populations. Although it is sub-lethal in most instances, avian malaria can result in anemia, lower fertility, and reduced migration ability. The Turtle Mountains is a unique ecoregion in North Dakota and provides habitat for various bird and mosquito species that differ from other parts of the state. Previous research has defined the mosquito fauna and occurrence of avian malaria in the Red River Valley region of eastern North Dakota and Northwest Minnesota; however, no research has been conducted in the …

Behavioral Responses Of Breeding Ducks To Unmanned Aerial Vehicle Surveys And Best Practices For Breeding Waterfowl Surveys Using Unmanned Aerial Vehicles, Mason Ryckman

Theses and Dissertations

Unmanned aerial vehicles (UAVs) have become a popular wildlife survey tool. As such, biologists are exploring the use of UAVs for surveying waterfowl. The most cited benefit of using UAVs over traditional methods is the idea of reduced disturbance, but this has had limited formal evaluation across species. We conducted UAV surveys with associated behavioral observations of ducks on wetlands and on nests during the 2019 – 2020 breeding seasons. We found species-specific behaviors among blue-winged teal (Spatula discors), northern shoveler (Spatula clypeata), and gadwall (Mareca strepera) including ducks noticing the aircraft, but reactions were generally less than traditional ground …

Effects Of Fractional Gravity On Human Gait, Elizabeth Nicole Smith

Theses and Dissertations

Only twelve humans have stepped on the Moon for a mere 80 hours. Further, noneof that Lunar exposure has been within the last 50 years. NASA’s Artemis Program recently announced that the next manned missions to the Moon will be scheduled for 2024 and 2025. With only a few years to prepare, it is pertinent that training for prospective astronauts reflects current scientific knowledge to ensure safety. In this study, the coordinative gait structures under 1.0g (Earth), as well as simulated 0.38g (Martian) and 0.17g (Lunar), were analyzed to discover critical changes in gait that may occur in these environments. …

Genetic Breed Association And Contraceptive Response Gwas Of The Feral Horses (Equus Caballus) Of Theodore Roosevelt National Park, Melissa Amy Thompson

Theses and Dissertations

Theodore Roosevelt National Park (TRNP) is home to a herd of feral horses (Equus caballus) which were present on the landscape prior to the establishment of the park and are now maintained as a living history demonstration herd. I used genomic analyses to investigate the TRNP horses’ relatedness to other breeds and the genetic basis for variation in response to a contraceptive vaccine. DNA from 118 horses was genotyped for 70k SNPs spread evenly across the genome. To clarify the relationship of this herd with other horses, I used population genomic analyses to compare the TRNP genotypes to a dataset …

Houghton Mifflin Harcourt Journeys Curriculum Series Longitudinal Effects On Grade 4 Student Reading Scores, Daniel Warcken

Theses and Dissertations

Within the last 100 years, the number of school districts in America has dropped by as much as 90% (Murdock, 2012), from 117,108 in 1939 to 13,452 in 2019 (National Center for Education Statistics [NCES], 2020). Funding and how to provide educational equity, equality, and justice for all is a critical conversation. According to the North Dakota Department of Public Instruction (NDDPI) (2018), 1.94% of the state’s $1.448 billion cumulative K-12 expenditures are associated with instructional media related to academic aids such as textbooks.

The purpose of this quantitative study was to identify if the major educational publishing company Houghton …

Meta-Analysis For Comparing Effect Between Game-Based Learning Versus Gamification Utilized In Nutrition Education, Chia-Lin Chang

Theses and Dissertations

The prevalence of obesity tripled from 1975 to 2016 and was declared as a global epidemic by the World Health Organization (WHO) in 1997 (Haththotuwa et al., 2020; "Controlling the global obesity epidemic," 2022). Nutrition education that involves knowledge and behavioral change is one major component addressing the problem ("Controlling the global obesity epidemic," 2022). Therefore, the effectiveness of each learning session is essential (Sharifirad et al., 2013). Thus, many nutrition educators have used gamified nutrition education to improve teaching effectiveness to increase healthy behavior or knowledge (Chow et al., 2020.; Munguba et al., 2008; Azevedo et al., 2019). Two …

Development Of The Share Your Story Program: Understanding How Self-Stigma And Mental Health Storytelling Influence Mental Health Experiences On College Campuses, Kyle Cromer Elliott

Theses and Dissertations

Mental health is a growing concern faced by college administrators. Self-stigma is a major barrier preventing mental health utilization and recovery on college campuses. The purpose of this research study is to understand how self-stigma influences the mental health experiences of college students.

The research study builds upon narrative inquiry—Honest, Open, Proud (HOP)—and the author’s lived experiences with mental health conditions to answer the research question: “How does self-stigma influence students’ mental health experiences on college campuses?”

Findings indicate that self-stigma and self-acceptance impacted if, how, and with whom research study participants shared their mental health conditions. Findings also show …

Evaluating Virtual Reality And Artificial Intelligence As Solutions For Delayed Flight Progress In Aviation Pilot Training, Ryan Paul Guthridge

Theses and Dissertations

Three studies in this dissertation examined a topic centered around delayed flight progress in aviation pilot training. Study one explored the impact of nonconcurrent flight laboratory training on the academic outcomes of collegiate aviation students, while studies two and three explored virtual reality and artificial intelligence as potential solutions to help alleviate the strain of delayed flight progress on the flight training organization. In the first study (n = 144), it was found that concurrent enrollment in an aviation classroom ground course and flight training laboratory positively impacts the mean academic block exam scores of students. In study two (n …

Small Mammal Community Ecology In A Northern Grassland, Lynda Lafond

Theses and Dissertations

I studied grassland small mammal community ecology at UND’s Oakville Prairie, in Grand Forks County, North Dakota summers 2018-2021. Specifically, I was interested in small mammal richness and abundance, investigating their habitat associations, investigating their phenotypic variation, and understanding their diets. I trapped small mammals for five consecutive nights at the end of June to early July 2018 – 2021. I also measured plant community composition and structure metrics. Over the four years, I captured 985 individuals from 11 species. Species richness and abundance varied spatially and temporally across the site. I most frequently captured meadow voles (Microtus pennsylvanicus), mice …

The Moral Foundations Of Attitudes Toward Mask Wearing, Kristen N. Leighton

Theses and Dissertations

As COVID-19 becomes endemic it is important to understand individual differences in motivation and adherence to mask wearing policies and recommendations. Mask wearing appears to be one way to protect communities, slow the spread, and save lives when COVID-19 rates spike in communities The main study aim was to examine how Moral Foundations Theory and Theory of Planned Behavior, specifically subjective norms, may explain individual differences in mask wearing to slow the spread of COVID-19. Understanding the psychological correlates of why and how often individuals wear a mask to slow the spread of COVID-19 can help community leaders, public health …

A Survey Of Research Administrators To Identify Areas Of Administrative Burden In Federal Research Grant Management, Jessica Lynn Schiller

Theses and Dissertations

Many processes in higher education are complicated by administrative burden and proceduralinefficiencies. The federal government and research universities partner to advance science and technology, but the federal research grant process is criticized for its lack of efficient and streamlined procedures. Staff and faculty alike lament losing valuable time to bureaucratic regulations, cumbersome processes, and burgeoning reporting standards. As the cost of higher education is increasingly scrutinized, current procedures must be analyzed to identify areas of excessive administrative burden and redesigned to maximize efficiency. To address this issue, a Qualtrics survey was deployed to research administrators to identify areas of administrative …

Translocation Of Yops By Yersinia Pestis Into Canine Cell Lines, Betsy Louise Young

Theses and Dissertations

Yersinia pestis, the causative agent of plague, secretes a set of virulence proteins called Yops when in contact with eukaryotic cells. A subset of these Yops is translocated directly into the cytosol of the host eukaryotic cells by the type III secretion system. Using a protein tag-based reporter system, this study is focused on the translocation of these Yops into the cytosol of canine derived cell lines: MDCK and DH82. The MDCK cell line is a canine derived epithelial cell line, and the DH82 cell line is a canine derived monocyte cell line. The reporter system uses a phosphorylatable peptide …

Optimization Of In-Vitro Tissue Culture And Transformation System For Sweet Sorghum Cultivars Using Immature Inflorescence, Logayn Abushal

Theses and Dissertations

Background: Sweet sorghum is a multi-purpose crop that can be used for human food, animal feed, and bio-fuel production. This crop is drought-tolerant and can therefore be grown in arid and semi-arid regions especially in marginal areas in Egypt. Nevertheless, production of Sweet sorghum cannot coup with the increasing demand in consumption as a food, and fuel due to a lag in scientific research regarding its genetic improvement. Therefore, genetic improvement of Sweet sorghum is innately required so that new traits of economic importance could be introduced; however, this can only be achieved through the establishment of a robust in-vitro …

The “Muddle” Of Landscape And Machinery In E.M. Forster’S Howard’S End And A Passage To India: An Ecocritical Reading, Ryan Ignatius Vera

Theses and Dissertations

This is an ecocritical reading of E.M. Forster's A Passage to India and Howard's End. I argue that Forster is concerned with imperial power structures that damaged the environment, as well as the looming aftereffects of the Industrial Revolution on both landscape and the people that reside in it.

Predicting Drug-Induced Liver Injury With Artificial Intelligence, Ting Li

Theses and Dissertations

Drug-induced liver injury (DILI) is an undesirable side effect to the liver caused by the common use of drugs, which is of great concern to the patients, physicians, the pharmaceutical industry, and government regulators. The current animal testing models do not present reliable results on the human DILI risk prediction during the preclinical phase. Therefore, there is an urgent need to find alternative methods to improve the human DILI risk prediction during the early stage of development. Utilizing the accumulated high-throughput transcriptomics profiles from L1000, we constructed an 8-layer deep neural network for human DILI prediction based on the largest …