Digital Commons Network^™

Investigating How Ecologically Relevant Thermal Conditions Affect Gonadal Development In A Turtle With Temperature-Dependent Sex Determination, Anthony Trey Breitenbach

Theses and Dissertations

In turtles and numerous other reptilian species, sex is determined by the environmental temperatures during embryonic development, which is referred to temperature-dependent sex determination (TSD). In the type of TSD common in turtles, cool temperatures (below 29 °C) during embryonic development produce mainly males while warm temperatures (above 29 °C) produce mainly females. Gonadal differentiation in TSD species involves numerous genes that are also necessary to produce a testis or ovary in species with genotypic sex determination. However, most of what we know about TSD comes from studies performed in the laboratory using constant temperature incubation conditions, which are not …

The Cynics' Understanding Of And Contribution To Philosophy, Yossra Hamouda

Theses and Dissertations

The Cynics are an understudied school in the history of philosophy especially, if we compare the amount of literature written on the Cynics to the amount of literature written on Socrates, Plato, Aristotle and other Greek schools like the Epicureans, the Neo-Platonists and even the Stoics. The lack of research interest in the Cynics, both from the side of philosophers and historians, is possibly grounded in a lack of interest in understanding the Cynical conception of philosophy. Unless we take a serious interest in understanding the Cynical conception of philosophy, we risk reducing the Cynics to the historical clowns of …

Animal Abuse In Egypt: An Assessment Of Attitudes, Behaviors And Protective Factors Among University Students And Graduates., Salma El Saedy

Theses and Dissertations

Animal abuse is an understudied problem in Egypt with possible ramifications on both non-human and human animals and links to interpersonal violence and conduct problems. This study aims to explore the attitudes and behaviors of Egyptian university students and graduates towards the treatment and use of animals in society and to test if exposure to animal abuse is associated with abusive behavior. The study also aims to identify possible protective factors against animal abuse among a group of positive deviants. A mixed-methods approach was used to study these questions; an online survey was disseminated over social media platforms, and 99 …

Characterization Of Testis-Derived Mesenchymal Cells And The Hunt For Universal Stemness Markers, Myret Ghabriel

Theses and Dissertations

Mesenchymal stromal/stem cells (MSCs) are multipotent cells residing in multiple tissues with the capacity for self-renewal and differentiation into various cell types. Due to the myriad sources of MSCs the International Society for Cellular Therapy (ISCT) proposed certain criteria for their characterization. Here, we isolate adult MSCs from mouse testes and demonstrate that these testis-derived MSCs (tMSCs) follow some of the ISCT’s criteria. tMSCs expressed the MSCs surface markers CD44, CD73, and CD29 and lacked the expression of the hematopoietic cell marker CD45. Moreover, the cells displayed the capacity for self-renewal and in vitro differentiation into adipocytes. Since the isolation …

Promoting Climate Change Mitigation & Supporting Ngos: Converging The Theory Of Planned Behavior & The Elaboration Likelihood Model, Passant Mostafa Halawa

Theses and Dissertations

In the 21st century, public opinion's attention in developed nations has increasingly been directed to climate change and the urgency for humanity to take action. The main discourse is that climate change would have devastating consequences on a global scale, threatening humanity’s existence. However, in most developing countries climate change is generally not regarded as an important topic and climate change messages suffer from poor public engagement. Most recent research has investigated climate change communication efficiency in developed countries. The novelty of this study lies in understanding the effectiveness of climate change messages in the Egyptian context. More specifically this …

Knockdown Of Mdm2 In Hepg2 Cell Line: A Step Towards Understanding The Relation Between Mirna590-3p And Its Downstream Target Gene, Mdm2, In Hepatocellular Carcinoma, Jihad Mahmoud

Theses and Dissertations

Background: miRNA 590-3p is a small non-coding RNA that has previously been associated with the occurrence and progression of several cancer types. Its expression pattern and biological role in Hepatocellular carcinoma (HCC), however, remain controversial. Interestingly, a previous study in our lab revealed a tumor suppressing activity of miR-590-3p in HCC and identified the MDM2 gene as the miR-590-3p target gene.

Aim: The current study aimed to knock down the expression of MDM2 in HepG2 cells to understand how the inhibition of MDM2, as a validated downstream target of miR-590-3p, would affect different functional pathways in HCC. In …

A Predictive Model For Geographical Location Using Microbiome Composition And Covid-19 Based Analysis, Ahmed Adel Aboushanab

Theses and Dissertations

The human microbiome is a main contributor for the health and welfare of the human body. It is affected by many factors like diet and hygiene. These factors differ between different populations. Testing the population-microbiome differences using healthy samples from different countries is the first objective of this study. This data was then used in training and testing machine learning models (Random Forest and L2-logistic Regression Classifiers) for the prediction of the geographical location based on the microbiome data. Random Forest Classifier had the highest accuracy. Feature importance analysis showed that the data for Proteobacteria, Actinobacteria, and Bacteroidetes improved the …

A Comprehensive Evaluation Of Wastewater Grit Characteristics And Its Application In The Design Of A Facility-Specific Grit Removal Solution, Tetiana Kolsovska

Theses and Dissertations

Tailored solutions for wastewater treatment plants (WWTPs) are becoming more prevalent for optimization of treatment process, based on the unique quality of the influent received by each facility. In-depth evaluation of the influent properties is necessary for design of the most appropriate treatment system. In this study, wastewater grit was evaluated in terms of its quantity, particle size distribution, total organic carbon (TOC) content, including fats, oils, and grease (FOG), and settling velocity of the particles, over the course of one year at the headworks, collection network, and through the treatment stages of the Atlantic County Utilities Authority (ACUA) WWTP, …

The Experiences Of Undergraduate Black Gay Men Who Use Hookup And Dating Apps While Attending A Predominantly White Institution, Tevis Denzell Bryant

Theses and Dissertations

The purpose of this study was to explore the experiences of undergraduate Black gay men who use hook up and dating apps while attending predominantly White colleges and universities. In using intersectionality as my theoretical framework, I was able to discover the essence of the experiences that Black gay men face while using these platforms. Intersectionality assisted the study in identifying the systems of privilege and oppression that are present for Black gay men, specifically when attempting to date within the LGBTQ+ community (Cho et al., 2013; Collins, 2015; Garcia & Ortiz, 2013). Through this framework I additionally began to …

An Empirical Study On The Efficacy Of Evolutionary Algorithms For Automated Neural Architecture Search, Andrew D. Cuccinello

Theses and Dissertations

The configuration and architecture design of neural networks is a time consuming process that has been shown to provide significant training speed and prediction improvements. Traditionally, this process is done manually, but this requires a large amount of expert knowledge and significant investment of labor. As a result it is beneficial to have automated ways to optimize model architectures. In this thesis, we study the use of evolutionary algorithm for neural architecture search (NAS). Moreover, we investigate the effect of integrating evolutionary NAS into deep reinforcement learning to learn control policy for ATARI game playing. Empirical classification results on the …

Selective Small Molecule Targeting Of Mcl-1 In Multiple Myeloma, Omar S. Al Odat

Theses and Dissertations

Multiple Myeloma (MM) is a deadly blood malignancy, characterized by the uncontrolled proliferation of aberrantly differentiated plasma cells. MM is challenging to diagnose and treat, accounting for approximately 12% of hematologic malignancies. The overexpression of anti-apoptotic group of Bcl-2 family proteins, particularly Myeloid cell leukemia 1 (Mcl-1), play a critical role in the pathogenesis of MM. The overexpression of Mcl-1 is associated with drug resistance and overall poor prognosis. Thus, inhibition of the Mcl-1 protein is an attractive therapeutic strategy against myeloma cells. Over the last decade, the development of selective Mcl-1 inhibitors has seen remarkable advancement. In this project, …

Advanced Materials For Skin Regeneration, Ingrid Safina

Theses and Dissertations

Massive skin loss, over 20% of the total body surface area, is challenging to heal (Rowan et al. 2015). Ideally, autologous skin grafts have the ability to support complete skin reconstruction. However, skin grafting faces major limitations, such as shortage of donor sites and secondary injury. Alternatively, advanced materials can be used to produce skin constructs that could potentially serve as skin substitutes (Stanton and Billmire 2002). Herein, we used two polymeric materials: graphene and polyurethane (PU) to produce films that support skin cells in their growth and maturation. The surface properties of these materials were modified to enhance their …

Flood Warning: A Generalized Approach To Forecast The Impacts Of Flooding Events Using Arcgis Pro, Qgis, And Python, Robert Evan Smith

Theses and Dissertations

Floods are the most common global natural disaster, and 1 billion people live in floodplains worldwide adding to the impactful damage that inundation causes. Disaster managers strive to mitigate damages to their communities but need to know what the impact of a potential flood may be. GEOGloWS ECMWF Streamflow Services estimates forecasted streamflow around the world. These forecasted streamflow's can be used to create predicted flood extent maps using Height Above Nearest Drainage (HAND) or Sedimentation and River Hydraulics - Two Dimension (SRH-2D). Another method to obtain a flood map is using Setinel-1 satellite Synthetic Aperture Radar (SAR) imagery. Flood …

Molecular Characterization Of Antibiotic Resistant Shiga Toxin-Producing Escherichia Coli From Clinical And Food Samples, Khulud Alotaibi

Theses and Dissertations

Antimicrobial resistance (AMR) in foodborne pathogens can be a consequence of using antimicrobial drugs in food-producing animals. The emergence of antimicrobial resistance in foodborne pathogens is of great concern due to adverse patient health outcomes and the possibility of transferring genes encoding AMR to other clinically relevant pathogens. One of these bacteria is Shiga toxin-producing Escherichia coli (STEC), which can cause serious illness in humans for a haemolytic uremic syndrome (HUS). This study characterized and determined the mechanism of antibiotic resistance in 46 Shiga toxin-producing Escherichia coli strains collected by the U.S. Food and Drug Administration from food and clinical …

An Exploration Of The Contextual Interference Effect On Trained Trick Retention In Companion Dogs (Canis Lupus Familiaris), Madeline Messina

Theses and Dissertations

The ability to enact behavior change is pivotal to dog training success. Currently, there are few studies informing the best training practices. This thesis sought to enhance current training practices by applying a human motor skill learning theory, the contextual interference effect (CI), to a trick-training paradigm with companion dogs.

"Nothing ‘Personal’ To Lose": Alice Notley’S “I” And The Poetics Of Encounter In Disobedience, Christina T. Baulch

Theses and Dissertations

Though the lyric-I has often been perceived as an isolated ego, Alice Notley's "I" in her long poem Disobedience (2001) necessitates plurality through what I call a "poetics of encounter." In response to the 1978 Language poetry manifesto "Aesthetic Tendency and the Politics of Poetry," and to the larger well-rehearsed debate about vocal homogeneity and persona centrism in poetry, this paper argues that Notley's poetics of encounter brings the "I" of Disobedience into continual and complex conversation with material history, politics, and mass culture, thus situating it within, and not sequestered from, the world and its mediation.

Opportunities For Wonder In A Public Park, Alexander Butler

Theses and Dissertations

Research suggests unstructured play is important to a child's mental and physical development, and the natural world provides excellent opportunities for formative experiences. Urban environments, however, present challenges to finding and enjoying wild spaces. The potential role of public parks, supported by a small survey of college students, is discussed.

Steve Mcqueen, The Filmmaker, And Kant’S Sensus Communis, Livia Melamed Margon

Theses and Dissertations

This thesis reflects on the ways in which art reinforces community and reduces political polarity by stimulating shared feelings, namely through Kant's idea of sensus communis. To illustrate its argument, this thesis analyzes the work of Steve McQueen, a politically aware, ethically engaged, and broadly recognized filmmaker and artist.

Afropolitan Manifestations In Contemporary African Art: Mobilizing Achille Mbembe, Petra Frank-Witt

Theses and Dissertations

This thesis explores Afropolitanism's conceptual-philosophical grounds and how its principles are mirrored in the arts. Achille Mbembe’s conceptualization is presented as a form of cultural cosmopolitanism, as shared by the artists presented, further distilled as a dynamic, forward-looking, emancipatory ideology that favors Africanness as open-ended signifier rather than overdetermined sign.

Play Among The Shadows, Xiong Wei

Theses and Dissertations

This article elaborates Xiong Wei's inspiration and experience from different cultural, political, social systems and art environment as a Chinese artist living in the United States, and the logic and methodology of how he went from a social realist sculptor to a contemporary artist.

I Just Work Here, Carrie Rudd

Theses and Dissertations

Via an in-depth analysis of the artist’s works and the material, social, and historical possibilities of Painting, the following paper investigates the myriad approaches for Painting to communicate complex ideas both physically and psychologically.

A Liquid Line, Sofía Del Mar Collins

Theses and Dissertations

My practice searches for fertility amidst cultural and material detritus. This paper outlines flows embedded in becomingness. My thesis exhibition included Liquidscapes, a series of suspended and wall hung paintings on plastic, Nursery of the Brave, a group of hanging vessels shaped from waste textiles, and Glass City, a video.

A Slippery Slope Of Resemblances, Lauren Clark

Theses and Dissertations

My studio has become an ecosystem. Plastics, linens and found objects are transformed with both “natural” and “artificial” dyes, pigments, and aggregates, until there is a co-corruption akin to an ecology. I am searching for an alternate relationship between phenomena, wonder and knowing.

Trees And Trees And Trees In Me, Areum Yang

Theses and Dissertations

Painting is a recording of my current psychology, and a window through which I can visualize my inner self. My painting won't make my anxiety go away, but it will allow me to work with my emotion and put it in a specific place, so it doesn't control my life.

Centrifugal Assembly Of Bijel Ropes Via Helical Microfluidics, Shankar P. Kharal

Theses and Dissertations

Bicontinuous interfacially jammed emulsion gels (bijels) are soft materials that retain a liquid bicontinuous network stabilized by an interfacially jammed layer of nanoparticles. In this thesis, we investigated a microfluidic twisting method to fabricate micro-ropes of nano-structured bijel fibers. This method shows how weak microfibers with tensile strengths of a few kPa can be reinforced by 4 orders of magnitude by means of microfluidic twisting. Microfluidic twisting allows to produce continuous bijel fiber ropes of controllable architecture. Modelling the fluid flow field reveals the rope geometry dependence on a subtle force balance composed of rotational and translational shear stresses. However, …

Controlling For Developmental Language Differences In Spanish-English Learners: A Comparison Of The Ortiz Picture Vocabulary Acquisition Test And Woodcock Muñoz Language Survey-Third Edition, Amanda Garcia

Theses and Dissertations

The purpose of this study was to determine whether there is a difference in the vocabulary knowledge of Spanish-speaking English Learners (ELs) when controlling for developmental language norms. This research was essential given the multitude of literature indicating the connection between vocabulary skills and later academic success and the substantial achievement gaps between ELs and English Speakers (ESs). Considering the different normative standards in the Ortiz PVAT and WMLS III English, where the former includes bilingual, exposure-based norms, and the latter does not, this study evaluated the vocabulary knowledge of 27 Spanish-speaking ELs between the ages of 5 and 11 …

Teacher Perceptions Of Empathy In Educational Leadership And Its Impact On School Culture And Climate: A Qualitative Case Study, Sari Goldberg Mckeown

Theses and Dissertations

The purpose of this qualitative case study is to examine teacher perceptions of empathy in educational leadership and its impact on school culture and climate. While research has started to emphasize the role of empathy among educational leaders, there is a lack of discussion on teacher perceptions of empathy among educational leaders and how they perceive it may actually affect school culture and climate. Prior to the COVID-19 pandemic, the field of education started experiencing an increase in job stress due to “inadequate school funding, balancing school management with instructional leadership, new curriculum standards, educating an increasingly diverse population, shouldering …

Environmental Attitudes Of Community College Students Concerning Age, Gender, And Race, Robert W. Fournier

Theses and Dissertations

Many studies have shown the mental, physical, and academic benefits of environmental education to students. Equally important, environmental education can develop our students into more environmentally minded citizens. However, we are learning that most students are not receiving accurate environmental information while in school, which may impact their attitudes toward the environment and subsequent actions to protect it. Understanding current college-aged students' (Generation Z's) attitudes toward the environment are critical as they are next in line to make political and business decisions that will affect our planet. Using the New Ecological Paradigm Scale (NEP), 1,556 community college students were surveyed …

Masculinity, Identity, And Performance In Virginia Woolf's Mrs. Dalloway And The Waves, Shannon M. Connors

Theses and Dissertations

By examining the male characters in Virginia Woolf’s Mrs. Dalloway and The Waves, this thesis seeks to explore the ways in which Woolf provides feminist commentary on masculinity, identity, and performance. In focusing on how these characters express emotion and perform masculinity, the novels highlight the ways in which men are expected to act as opposed to how they feel. This is seen in the interactions between Woolf’s characters as she showcases relationships between men and women, as well as those men have with each other. In Mrs. Dalloway, Peter Walsh and Richard Dalloway both perform masculinity by expressing their …

Campy Musical Black Queer Forms: Finding Utopia In Lil Nas X’S World Of Montero, Jaymi Leah Grullon

Theses and Dissertations

Lil Nas X, a breakout music star has broken into the mainstream and has stirred up controversy and moral panic among conservative Christians as well as those who are not in support of over Black queer representation in media. Moreover, I am interested in which ways he queers the forms of pop, hip hop and camp through his music videos, “Montero (Call Me By Your Name),” “Industry Baby,” featuring Jack Harlowe, and his performative skits. In my first chapter, I will be laying down the theoretical framework that I will be connecting from various scholars to define campy musical Black …