Digital Commons Network^™

Environmental Trade-Offs Of Reverse Osmosis Water Purification Units (Rowpus) And Bottled Water, Caleb A. Boone

Theses and Dissertations

The Department of Defense (DoD) conducts many remote missions around the globe. As part of any remote basing strategy, potable water needs to be secured. Currently, there are three primary means of procuring potable water at remote locations: bottled water, on-site purification, or tie-in to existing, local infrastructure. The purpose of this study is to determine the environmental tradeoffs of bottled water and on-site treatment via a Reverse Osmosis Water Purification Unit (ROWPU), which uses multiple levels of filtration to make potable water from freshwater or saline water. A cradle-to- gate assessment was developed for both systems to create a …

Applications Of Fragile Curves To Water Distribution Networks, Danielle M. Van Lanen

Theses and Dissertations

Water distribution networks are of critical importance to provide uninterrupted services to a city. Not only do they provide potable drinking water to customers they also are used for fire services and other emergency support functions. By the year 2039, the United States’ drinking water investment gap is estimated to grow to $136 billion dollars. As the gap between available funding and funding required, being able to prioritize assets for investments is critical. Unfortunately, water distribution networks are typically managed reactively rather than proactively. This paper showcases a methodology for a proactive approach to asset management through the use of …

Effects Of Occupationally Military-Relevant Particle Mixtures (Sio2, Cdo, Cr2O3) On A549 Human Pulmonary Epithelial Cells, Isabella M. Muffoletto

Theses and Dissertations

In the course of maintaining a safe, mission-ready aircraft fleet and operational runways, United States Airmen experience a range of occupational risks. These risks include inhalable hazards generated from oft-used maintenance practices, such as blasting which emits silica from the media abrasives as well as contaminants from the exterior coatings. Additional inhalation hazards range from engine and fuel emissions, chemical agents, radiation, and explosives, to naturally occurring and human-manufactured biopathogens. Of notable concern are emissions in forward-deployment areas, including urban pollution, particulates released from runway construction and maintenance activities, and combustion from burn pits containing hazardous and unknown combinations of …

Investigating The Molecular Mechanisms Of Spore Killing By Neurospora’S Meiotic Drive Elements, Nicholas Rhoades

Theses and Dissertations

Meiosis is a fundamental and highly conserved biological program that is required for sexual reproduction in eukaryotes. During meiosis, duplicated chromosomes synapse with their homologous partner and undergo a physical exchange of genetic material through recombination. The meiotic products resulting from this program contain novel combinations of alleles that are inherited by individuals in the succeeding generation. The random assortment of alleles during meiotic recombination allows for the chance that any such allelic combination may provide an increase (or decrease) in fitness for an individual. Alleles, or combinations of alleles, that are beneficial to the organism may be retained within …

County-Level Social Determinants Of Health And Covid-19 Health Outcomes, Bret R. Lyman

Theses and Dissertations

Social determinants of health are associated with a variety of negative health outcomes, including COVID-19 morbidity and mortality. However, most research evaluating this relationship have been case studies, retrospective cohort studies, and case series studies and/or have used use analytic techniques, such as linear regression, that can struggle to adequately model the social determinants' complex nature. This study used United States county-level social determinants of health data and March 2020-December 2020 COVID-19 morbidity and mortality data. Structural equation modeling was used to develop a latent measurement model for the social determinants of health. Substantial cross-loadings among the social determinants of …

Effect Of Nitrogen On Seed Sugar Content In White Corn ( Zea Mays L. ), Douglas Otieno Ndege

Theses and Dissertations

Abstract.White corn (Zea mays L.) is a grain crop that produces kernels in a cob and is grown in different parts of the world. Depending on the maturity stage at harvest, the most common are field corn variety and sugar corn variety. Notably, Nitrogen (N) fertilizer is an important element in improving soil fertility and affecting crop productivity. The objective of this research study was to determine the effect of Nitrogen on kernel sugar concentration in white corn and investigate the effect upon white corn yield and grain mass. The study was conducted at the Illinois State University research farms …

Developing Methods For Measuring In Vivo Lipid Metabolism, Russell L. Denton

Theses and Dissertations

Lipid metabolism is critically important to the normal function of individual cells and for signaling between tissues of the human body. There is a great need to quantify changes in lipid metabolism because of its implications in both normal healthy conditions and during disease development. In our first study, we developed a liquid chromatography mass spectrometry based workflow to assess in vivo metabolism of murine brain lipids. This involved sample preparation, data acquisition, and analysis software development and improvements. Regarding sample preparation, we maintained the mice at 5% body water for the duration of the experiment. As mouse metabolism proceeds, …

“Tweeting During Emergencies”: The Egyptian Ministry Of Health Twitter Communication Strategy Under The Umbrella Of The Crisis And Emergency Risk Communication Model (Cerc) Case Study: Covid-19 Pandemic, Pakinam Elgohary

Theses and Dissertations

This research investigates using the Crisis and Emergency Risk Communication Model (CERC) for COVID- 19 communication by analyzing the content of Twitter messages posted by the Government of Egypt through the Egyptian Ministry of Health (MOHP). It further examines how official communicators and institutions utilize social media to contact the public during emergencies like the COVID-19 pandemic, highlighting critical strategies of recommendations. Crisis and Emergency Risk Communication (CERC), a five-staged theory, recommends a set of messaging and pertained communication characteristics to implement at each stage of the identified following stages: (1) “Pre-crisis, (2) Initial event, (3) Maintenance, (4) Resolution, and …

Biogas Combustion Characteristics In A Concentric Flow Slot Burner: Effects Of Co2 Concentration On Stability And Flame Structure, Maged Kiriakos

Theses and Dissertations

Biogas combustion is affected by the concentration of carbon dioxide. The successful applications of Biogas as a sustainable renewable alternative fuel produced from waste depend on its combustion stability, heat release, and pollution level. The aim of the current study is to apply new combustion technology and study the stability and combustion characteristics of natural gas with different percentages of carbon dioxide from 0 to 40% simulating biogas fuel. The stability characteristics and the temperature profiles of turbulent planar flames at different levels mixture inhomogeneity are investigated and presented in this work. The flames are created in a newly developed …

Neuroprotective Effects Of Green Tea (Camellia Sinensis) And Broccoli (Brassica Oleracea) Extracts In An In Vitro Model Of Multiple Sclerosis, Sara Taha Fathallah

Theses and Dissertations

Multiple Sclerosis (MS) is a neurodegenerative autoimmune disease in which the immune system attacks the central nervous system (CNS) resulting in demyelination. Currently, there is no specific treatment for MS. Here, we propose testing the neuroprotective potential of Green tea (Camellia sinensis), and Broccoli (Brassica oleracea) extracts in an in vitro model of multiple sclerosis.

Methods and Results: Green tea and Broccoli plant extracts were analyzed with GC-MS and tested for their neuroprotective effects in an in vitro MS model using Cuprizone (CPZ) on the Human neuroblastoma SH-SY5Y cell line. Cell viability assays proved the safety of the extracts …

On The Balcony, Beyond “Balconearing”; Perception Of Cairene Women, Behind The Curtains., Rowida Magdy Al-Gebeily

Theses and Dissertations

This study sheds light on the significance and role of threshold spaces as means of accomplishing sociocultural needs, restoration and wellbeing in the residential environment. Understanding the function and uses of these spaces allows us to appreciate their benefits that are often neglected. The research particularly focuses on the social dimension of one fundamental threshold space; the Cairene balcony. It is an integral space that provides a valuable connection to the outside, and its importance in the development of urban living is widely recognized. If carefully designed to meet the residents’ needs and demands, they can promote a better quality …

Molecular Diagnosis Of Non X-Linked Ectodermal Dysplasias Using Next Generation Sequencing, Eman Abdelalim Rabie

Theses and Dissertations

Ectodermal Dysplasias (EDs) are rare heterogenous monogenic developmental disorders sharing the impairment of at least two surface ectoderm-derived organs. Symptoms characteristically manifest developmental abnormalities of the teeth, and three skin derivatives: hair follicles, nails, and sweat glands. The disease-causing gene was identified for only fewer than half of 160 characterized ED phenotypes. Expectedly, ED-causing genes regulate or function in ectodermal-developmental processes. The most common phenotype is hypohidrotic ED featuring teeth agenesis, and diminished or complete absence of hair and sweat production. Disease-causing variants of EDA, EDAR, EDARADD and WNT10A genes were identified in 60-90% of ED patients in …

Effects Of Date Seed (Phoenix Dactylifera) Extract In An Animal Model Of Diabetes Mellitus, Sara Refaat

Theses and Dissertations

Diabetes mellitus is a chronic illness and a global epidemic. The commercial diabetic medicines available are expensive and have several adverse effects. Alternative natural products are still being sought for. Date seeds ( Phoenix dactylifera) are either thrown away as garbage or utilized as animal feed. The use of seed extract as an alternative therapy for diabetes offers a cost-effective and all-natural method for managing the disease. Methods Sprague dawley rats were randomly distributed into groups with a sample size of 4 rats per group. Date seed powder was boiled producing a 10% date seed extract which was administered in …

Factors Affecting Consumers’ Purchase Intentions Towards Recycled Products, Sherine Esmat

Theses and Dissertations

The work executed addresses the status of recycling industry in Egypt and its relation to the current sustainability trends as well as climate change issues. It also identifies the main concerns of consumers when purchasing recycled products. Consequently, identifies the key pillars that need to be applied or communicated with the target consumers to enhance the concept of selling recycled products and increase its market share. Since this industry is significantly broad, the focus of the study was only on recycled PET plastic bottles (rPET), this is to ensure attaining accurate and reliable results.

An interview and a site visit …

Deep Learning Architectures For Visual Question Answering On Medical Images, Venkat Ramana Kodali Kodali

Theses and Dissertations

The purpose of this research is to apply both computer vision and natural language processing techniques for visual question answering (VQA) on a medical image dataset. Deep learning and machine learning libraries were used in the research. The research includes understanding key achievements in the field of visual question answering, identifying techniques applied in general images and applying them along with new techniques to medical images. There are many more articles explaining the application of visual question answering to general images than on applying VQA specifically to medical images. In this research, I initially developed a model of VQA that …

A Review Of Covid-19 Lockdown Across Different Countries During 2020: Characterization Of Risk Factors And Severity Of Covid-19 In Egyptian Patients, Hanya Mohamed

Theses and Dissertations

On March 12, 2020, The World Health Organization (WHO) announced the new coronavirus 2019 as a global pandemic. In January 2022, the number of COVID-19 cases reached 300 million confirmed cases with a total death count of 5.5 million cases. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was identified in a seafood wholesale market in Wuhan, China. At the time of the outbreak, there was no effective treatment to protect from the novel coronavirus; the only way to control the pandemic was through reducing person-to-person contact and taking preventive measures based on the severity of the disease among the population. The …

What Is A Child? The Conception Of Childhood Viewed Primarily Through The Funerary Culture From The Predynastic Era To The Middle Kingdom, Courtney Mcrae

Theses and Dissertations

This thesis uses an interdisciplinary analysis of the theories involving cultural ideas of childhood, as well as archaeological approaches to studying the funerary material culture related to children, in an attempt to determine the role of children in ancient Egypt. To achieve this, the author examines grave goods in relation to child burials from the Predynastic (5000-3200 BC) to the Middle Kingdom (2055-1650 BC) to examine the correlation between funerary material cultures with different stages of childhood. The author used these time periods in order to properly conduct an in depth analysis of early Egyptian culture. The author also analyzes …

A Universe Of Mirrors: The Mirror Metaphor In Ibn ʿArabī’S Thought In Relation To Ontology, Knowledge, And Perfection, Basma Eletreby

Theses and Dissertations

The mirror metaphor is ubiquitous in sufi texts. It operates uniquely in Ibn ʿArabī’s thought and writings as a representation of his conception of the cosmos. Being, knowledge, and perfection are among the seminal themes of al-Shaykh al-Akbar’s thought, and the mirror metaphor is employed in revealing their reality in his writings. As opposed to Unity of Being, a term that Ibn ʿArabī does not employ, the mirror embodies the pillars of Ibn ʿArabī’s conception of Being through representing the quintessential huwa lā huwa, the configuration of oneness and manyness, and most importantly, the definition of the relation between God …

Skeleton-Based Hand Gesture Recognition Using Data-Level Fusion, Oluwaleke Yusuf

Theses and Dissertations

Hand Gesture Recognition (HGR) is a form of perceptual computing that allows artificial systems to capture and interpret human gestures. HGR has applications in human-machine interaction, virtual reality, augmented reality, and human behavior analysis. The human hand can assume a near-infinite number of poses and orientations to form myriad gestures, thus increasing the difficulty of the HGR task.

The hand skeleton of connected joints effectively describes the hand’s geometric shape and thus contains richer semantic gesture information while eliminating noise from individual differences in physical hand characteristics. The efficacy and computational efficiency of skeleton-based HGR frameworks can be significantly enhanced …

The Egyptian National Action Plan Of Antimicrobial Resistance: Governance Mechanism And Public Awareness, Aalaa Afdal Mogheith

Theses and Dissertations

This research aimed primarily to understand the governance mechanism adopted for improving the public awareness on Antimicrobial Resistance (AMR) as the first goal of the Egyptian National Action Plan (NAP) for curbing AMR. The secondary purpose was to assess the public awareness, and to identify areas for improvement on raising awareness on AMR. A mixed approach was adopted; firstly, eight in-depth interviews with different stakeholders` representatives involved in the NAP development were held to understand the governance of the NAP. Secondly, a public awareness survey was conducted on 565 respondents to assess their knowledge and awareness on AMR and antibiotic …

Carbon Dioxide Capture Potential Of Chitosan-Nanocrystalline Cellulose Aerogel Composite Materials: Synthesis, Functionalization, And Characterization, Victor Oghenekohwo

Theses and Dissertations

The carbon dioxide capture technology has been established as an invaluable player in the current global efforts to allay the warming of the planet and climate change. In this connection, the study centers on the valorization of waste organic materials for the application described herein. The sorbents, sourced from a combination of by-products of food processing and agricultural residue waste products, viz. seafood waste and sugarcane bagasse, showed prospects for selective carbon dioxide capture, adsorbing up to 5.78 mg/g of the gas at 273 K and 2.82 mg/g at 298 K, as observed on the Micromeritic ASAP 2020 surface area …

Adsorption Of Antibiotics In Wastewater By Stevia Rebaudiana Zinc Oxide Nanoparticles, Hania Guirguis

Theses and Dissertations

Green zinc oxide nanoparticles (ZnO NPs), synthesized using Stevia rebaudiana extract, are investigated as novel adsorbents for the removal of the antibiotics ciprofloxacin (CIP) and tetracycline (TET) from water. The green ZnO NPs were synthesized using a novel, rapid and ecofriendly technique that utilized a natural source with high sugar content as a reducing agent and a less energy intensive approach that did not require annealing or calcination at high temperatures. The particles are mesoporous, with a hexagonal wurtzite structure, a BET surface area of 15.28 m2/g and a size range of 37.36-71.33 nm. At pH 5, the green ZnO …

An Analysis Of The Ash’Ari-Mu’Tazilite Conflict In The Ḥāshiya Of Ibn Al- Munayyir In Al-Kashshāf By Al-Zamakhsharī, Nabil Haskanbancha

Theses and Dissertations

In this thesis, I analyze the Sunni Ash’ari response to the Mu’tazilite Qurʾan commentary al- Kashshāf written by al-Zamakhsharī (d.538/1144), and the significant role of the gloss commentary (hashiyā) in highlighting the theological debates between Ash’ari and Mu’tazilite scholars. Alongside the main commentary, this thesis demonstrates the pivotal role of the hashiyā in Islamic studies through its intersection with theology and philology, uncovering active debates on the critical interpretations of the text by exegetes. Al-Kashshāf is the most commented text in the tafsir genre despite its Mu’tazilite influence, mostly receiving criticisms from conservative Sunni scholars. The first Ash’ari scholar to …

Electrochemical Sensors And Biosensors Of Biomarkers And Therapeutic Agents Detection, Mahmoud Abdelhakem

Theses and Dissertations

Electrochemical sensing is a pioneering tool amongst all other sensing techniques even though it had been started in the early 20th century. Due to their cost efficacy, accuracy, and real-time measurement, electrochemical sensing has been utilized in a vast of biomedical applications in therapeutic drug monitoring and biomarker detection. This thesis work concerned the monitoring of three therapeutic agents in spiked plasma, urine, dosage form, and interstitial skin fluid with high specificity and accuracy. Two of our sensing platforms utilized nanomaterials for sensing (sensors) of Cilostazol and Velpatasvir utilizing α-MnO2-V2O5 (metal oxide nanorods) and NH2- MIL-53 (Aluminum-based metal organic frameworks), …

Integrating Multiliteracies In A Third Grade Classroom To Enhance Student Engagement And Motivation, Rebecca K. Mcdonough

Theses and Dissertations

The purpose of the study is to investigate the growth in student motivation and engagement through a multiliteracy lens. The specific aim is to explore what happens when a traditional writing unit is replaced with a multiliteracy writing unit that utilizes multimodal components. The students demonstrated changes in how they perceived themselves as writers and how they viewed writing in general. The implications for teaching writing with a multiliteracy approach is also discussed.

Polyethyleneimine Shell Nucleic Acid Nanostructures From Gold Nanoparticle Template For Chemotherapeutic Drug Delivery, Brendan Guy Rucci

Theses and Dissertations

The next generation of anticancer agents will emerge from rationally designed nanostructured materials. This work involved the synthesis and characterization of novel hollow DNA-conjugated gold nanoparticles (DNA-AuNPs) for controlled drug delivery. Polyethyleneimine (PEI) was bound to citrate-capped AuNPs, forming polymer-shell nanoparticles. Dissolution of the gold core via iodine formed hollow core polymeric nanoparticles (HCPPs) and a high density of DNA (85 molecules/particle) containing daunorubicin was conjugated. Particles were spherical with an average diameter of 105.7±17.3 nm and zeta potential of 20.4±3.54 mV. We hypothesize the DNA backbone electrostatically condensed to the primary amines on the surface of the particle toroidally, …

A 3d Bioprinted Hydrogel Microfluidic Device For Screening Applications, Anant Bhusal

Theses and Dissertations

The microfluidic enabled the integration of engineered miniaturized tissue models for drug screening. Conventional polydimethylsiloxane or plastic-based devices require multiple fabrication steps, which are challenging. We developed a 3D bioprinting approach to create prototypes of hydrogel-based multi-material microfluidic devices integrated with microtissue models. The approach utilizes poly(ethylene glycol) diacrylate and gelatin-methacryloyl to create microfluidic chips using multi-material bioprinting capacity with a high resolution of 15µm on x-y and 50µm on the z-axis and post-printing viability of >90%. We demonstrated easy regulation of stiffness from 24±5 kPa to 1,180±9 kPa and burst pressure from 16±1kPa to 256±19 kPa in the chip …

The Association Between Civic Engagement Via Participatory Art And Adolescents’ Self-Esteem And Self-Efficacy, Michaela Ann Hayes

Theses and Dissertations

Civic engagement refers to actions taken by individuals to address issues of public concern, which can come in many forms including engagement in art. Participation in these activities can have positive impacts on the individual, including improved mental and physical health, as well as on the community through increased appreciation for differences and acquisition of values such as tolerance. The Bioecological Model suggests that an individual's participation in civic activities is influenced by the various levels of their environment. These experiences may be particularly impactful for adolescents. Indeed, adolescents who participated in civic engagement activities have been found to have …

The Effect Of Alcohol On Lipid Membrane-Membrane Fusion And Snare Proteins, Robert E. Coffman

Theses and Dissertations

Currently the treatment of alcohol use disorder is very difficult and often requires the combination of therapy and medications, with many who undertake treatment experiencing relapse over time. There is also no treatment in use to prevent the development of alcohol use disorder. It is the aim of this work to provide information that may be useful for the development of a preventative treatment for developing alcohol use disorder by elucidating more of the acute effects of alcohol use. It is known that these effects originate in the brain. Within the brain are circuits made up of neurons that communicate …

Comparative Metabolite Profiling And Fingerprinting Of Mature And Immature Grains Of Different Species Using A Multiplex Approach Of Lc-Ms And Gc-Ms Coupled To Chemometrics, Doaa Bahaa Abdelhalim Saied

Theses and Dissertations

The objective of the current study was the assessment of heterogeneity amongst metabolites of 5 cereal and leguminous grains of different species, and cultivars i.e., Triticum aestivum L., Hordeum vulgare L., Vicia faba L. & Cicer arietinum L. at different maturity stages. Gas chromatography mass-spectrometry (GC-MS) post silylation technique was employed for nutrients profiling. A total of 70 peaks belonging to sugars, fatty acids/esters/steroids and organic acids were identified including sucrose, melibiose, glucose and fructose as major sugars, butyl caprylate, hydroxybutanoic acid and malic acid to contribute for the discrimination between grain species and different maturity …