Digital Commons Network^™

The Effects Of Footshock On The Reinforcing Efficacy Of Cocaine In Male Long-Evans Rats, Elizabeth S. Hendrick

Theses and Dissertations

Many links exist between cocaine abuse and stress. The literature and laboratory studies in rats suggest that this could be because stress increases the reinforcing efficacy of cocaine. Using male Long-Evans rats, experiments in this thesis tested effects of footshock on the reinforcing efficacy of cocaine using a progressive ratio schedule of reinforcement. They also examined effects of footshock on the reinforcing efficacy of a half-maximal dose of cocaine. Finally, they tested the effects of footshock on cocaine self-administration in rats initially resistant to acquisition of cocaine self-administration. Footshock did not increase reinforcing efficacy of cocaine on a PR schedule …

Daubechies And Quadratic B-Spline Wavelets For Automated Early Diagnosis Of Alzheimer's Disease, Genevieve Jacques

Theses and Dissertations

Alzheimer's disease is a neurological disorder characterized by nerve degeneration and neuronal death. The diagnosis of Alzheimer's disease at an early stage is a major concern due to the lack of a standard and effective diagnosis procedure available to community healthcare providers, as well as the increasing numbers of the elderly population affected. Clinical evaluation, the standard AD diagnostic procedure conducted at major university hospitals and research clinics, achieves, on average, a positive predictive value of 93%, with a sensitivity of 83%, specificity of 55% and an overall accuracy of 75%. An effective and objective tool for early diagnosis of …

An Investigation Of Multi-Dimensional Evolutionary Algorithms For Virtual Reality Scenario Development, Scott Papson

Theses and Dissertations

Virtual reality (VR) has emerged as a powerful visualization tool for design, simulation, and analysis in modem complex industrial systems. The primary motivation for this thesis is to develop a framework for the effective use of VR in design-simulation-analysis cycles, particularly in situations involving large, complex, multi-dimensional data-sets. This thesis develops a framework that is intended to support not only the integration of such data for visual, interactive, and immersive displays, but also provides a method for performing risk analysis. Previously "static" VR environments are enhanced with time-evolutionary capabilities. Four candidate algorithms are evaluated for this purpose – deterministic modeling, …

Heterogeneous Multi-Sensor Data Fusion Using Geometric Transformations And Parzen Windows For The Nondestructive Evaluation Of Gas Transmission Pipelines, Joseph Anthony Oagaro

Theses and Dissertations

The natural gas transmission pipeline network in the United States is a key component of the nation's energy supply infrastructure and extends for over 280,000 miles and has an average age of over 60 years. The integrity of the pipeline is maintained by periodic inline inspections using magnetic or ultrasonic pigs. Defect characterization algorithms developed using current pigging data are hampered by the fact that single inspection techniques (either magnetic or ultrasonic) do not yield sufficient information for accurately and repeatably characterizing defects. This thesis demonstrates that defect characterization algorithms using multiple inspection techniques can accomplish this task. In particular, …

The Effect Of Prostaglandin Inhibitor On Pregnancy Rates Of Heifer Embryo Transfer Recipients, Jared William Mcnaughtan

Theses and Dissertations

Manipulation of the reproductive tract results in increased levels of prostaglandin, which may, in turn, reduce pregnancy rates in embryo recipients. Administration of a prostaglandin inhibitor prior to embryo transfer improves pregnancy rates in cows. Embryo transfer into heifers is more difficult and often requires additional manipulation of the uterus. This study was designed to determine whether administration of the prostaglandin inhibitor, flunixin meglumine, immediately prior to embryo transfer increases pregnancy rates in heifers. Heifers (n=466) were divided into two equal groups based on BCS (range=6-7) and weight (range=256-455). Estrus was synchronized in heifers by giving two injections of prostaglandin …

New Product Launch Decisions Under Competition And Uncertainty: A Real Options And Game-Theoretic Approach To New Product Development, James O. Ostler

Theses and Dissertations

New product development is central to many firms' future success. Not only as a means to continue to maintain their piece of the market, but product development can also be a strategic means for a company to diversify, and/or alter focus to adapt to changing market conditions.

Most of the research in new product development has been on how to do it cheaper and faster than the next guy. However, early commercialization does not guarantee a position of strength in the market. Failures of EMI in CT scanners and Xerox in personal computers illustrate that being first to market does …

An Architecture Design For A Real-Time Web-Based Visualization In The Grid Environment, Bhargavi Sura

Theses and Dissertations

Situations like war, terrorist attacks, fire accidents, floods, storms, etc., which threaten human life and property, demand immediate action to decrease the damage caused by them. A system is needed that predicts the future events based on what has happened and notifies the concerned personnel. The situation could be better understood in less time if the data is represented as colored, shaded and moving images rather than as numbers. Such a system requires a real-time Web-based visualization system with easy and secure access to grid resources, presenting easy-to-read graphics through a simple interface provided by a Web browser, and responding …

An In Vitro Evaluation Of Chitosan As A Biomaterial Focusing On The Effects Of The Degree Of Deacetylation, Virginia Hamilton

Theses and Dissertations

The material characteristics play a role in the suitability of chitosan for biomedical applications. This is not surprising since the degree of deacetylation of chitosan influences antimicrobial activity, degradation rate, immune reaction and mechanical properties such as strength and elongation. This study examines chitosans of variable material characteristics for wound and bone healing applications. Chitosan films of 76, 78, 80, 87, 91, 92, and 95% degree of deacetylation were tested in vitro for cellular responses by fibroblast and bone cell lines. The in vitro responses were compared to the material characteristics of molecular weight, degree of deacetylation, swelling index, and …

Imposing Cyclic Strain On Osteogenic Stem Cells: The Effects Of Strain Levels And Repetition Of Cyclic Strain In An Implant Environment, Daniel Henlee Smith

Theses and Dissertations

Bone and bone cells have been shown to respond to mechanical forces placed upon them. Particularly, strain plays an important role in osteogenic differentiation of marrow cells around artificial implants in bone. These strains, depending on their magnitude, duration, and repetition, can alter the proliferation and matrix synthesis of osteoblasts. To test how strain parameters influence osteoblast behavior, a four-point bending apparatus was used to impose cyclic strain on osteogenic stem cells isolated from rats and seeded on titanium plates. Cells were stimulated at 1 Hz for 15 minutes daily and compared to an unstrained control. Stimulation occurred at two …

Visualization Of Computer-Modeled Forests For Forest Management, Mahnas Jean Mohammadi-Aragh

Theses and Dissertations

Forest management is a costly and time-consuming activity. Remote sensing has the potential to improve the process by making it cheaper and more efficient, but only if appropriate characteristics can be determined from computer-models. This thesis describes the implementation of a forest visualization system and a corresponding user study that tests the accuracy of parameter estimation and forest characterization. The study uses data obtained from field-surveys to generate a computer-modeled forest. Five different stands were tested. Based on the quantitative results obtained, generally, there is no statistically significant difference in parameter estimation when comparing field-recorded movies and computer-generated movies.

Gas Hydrates To Capture And Sequester Co2, Tao Ding

Theses and Dissertations

Reducing atmospheric CO2, a main source of greenhouse gas, has been accentuated recently. One focus is capture, separation, and sequestration of industrial CO2. As a hydrate former, CO2 forms hydrates at moderate temperatures and pressures. This phenomenon could be utilized to capture and separate CO2 from flue gases, and also has the potential to sequester CO2 in the deep sds. This research investigated the CO2-N2 separation efficiency of gas hydrates; it investigated the sequestration potential of CO2 hydrates in ocean sediments. The catalytic effect of surfactants in these processes was investigated. A fluorosurfactant FS-62 was mixed with SDS at 100ppm/1000ppm …

Hispanic Students' Beliefs Regarding Emergent Literacy: A Case Study, Jacqueline L. Breland Worley

Theses and Dissertations

The purpose of this study was to identify the beliefs of the participants with regards to emergent literacy. Another purpose was to identify literacy practices employed by the participants while teaching preschool children. An additional purpose was to determine if participation in the course entitled ?Emergent Literacy? changed any beliefs of the participants regarding emergent literacy and subsequent literacy practices employed while teaching preschool children. The final purpose of this study was to determine the beliefs of the participants regarding emergent literacy and subsequent literacy practices employed while teaching preschool children, three years after completing the course entitled ?Emergent Literacy.? …

Effects Of Video Modeling On Skill Acquisition In Learning The Golf Swing, Joshua L. Smith

Theses and Dissertations

The purpose of this study was to determine the effects of video modeling on skill acquisition in learning the golf swing. One-hundred-eight college students participated in this study. All participants were pre-tested via videotaping to determine initial skill level. The pre-test videotaping was analyzed using DartTrainer software. Each participant was randomly assigned to one of three groups (1) control (2) single-view or (3) multi-view. Participants in the control group viewed a compact disc (CD) with a putting demonstration repeated 40 times. The participants in the single-view group viewed a CD with a front view only demonstration repeated 40 times of …

Identification Of Proteins Involved In Chloroplast Dna Replication, Matthew G. Lassen

Theses and Dissertations

Chapter 1

Chloroplast nucleoids (ct-nucleoids) are DNA/protein complexes involved in compacting the chloroplast genome, and may play a role in regulating DNA replication. Ct-nucleoids were isolated from young soybean plants and separated by 2-D gel electrophoresis. Gel spots were excised and analyzed by MALDI-ToF mass spectrometry, resulting in several protein identifications. The proteins identified all have functions unrelated to DNA replication. While some of these proteins may be due to contamination, it is possible that some of these proteins are dual-functional, playing direct roles in the regulation of DNA replication.

Chapter 2

A 28 kDa soybean protein was isolated by …

Distribution Of Chemistry And Sexual Fecundity In The Lichenized-Fungi, Xanthoparmelia Cumberlandia And Xanthoparmelia Coloradoensis On Boulder Mountain, Aquarius Plateau, Ut, Heather Bird Jackson

Theses and Dissertations

Three aspects of Xanthoparmelia cumberlandia and Xanthoparmelia coloradoënsis populations found at two elevations are explored: clustering of secondary chemicals and the resulting implications for taxonomic distinctions, the usefulness of thallus size as an indirect measure of sexual fecundity, and the frequency of sexual reproduction.

First, we use clustering of 46 chemicals produced by X. cumberlandia and X. coloradoënsis to evaluate the adequacy of the current taxonomic distinction between them. Using principal components analysis and UPGMA, we find that the currently recognized species boundaries indicated by the presence of stictic acid in X. cumberlandia and salazinic acid in X. coloradoënsis are …

Technology Literacy In The 21st Century: Teacher And Student Outcomes Of A Technology Innovation Program Model, Mary Beth Kelley-Lowe

Theses and Dissertations

The study investigated student and teacher outcomes from a Technology Innovation Challenge Grant project, NatureShift Linking Learning to Life (NS), to determine if the project influenced teachers’ work and student learning. The approaches were twofold: (1) to examine the implementation of higher order thinking and relevant use of technology by students and teachers and (2) to understand a teacher’s reactions to and implementation of a teaching model and methodology for Internet delivery and technology use.

A quantitative study examined the student projects and teacher materials created as part of school implementations cf the NS model and curriculum. The sources of …

The Effects Of Exposure To Images Of The Male Muscular Ideal On Body Image And Muscularity Concerns In Men, Jason Alan Mccray

Theses and Dissertations

Though body-image has been well-researched in women for more than 40 years, theoretical discussions and empirical investigations addressing male body-image have only recently began to emerge. Work by Pope, Phillips and Olivardia (2000) has begun to identify the dynamics of male body-image distortions and the role media depictions of muscular men may play in their pathogenesis. The empirical literature is curiously devoid of experimental investigations of male responses to media and advertising depictions of muscular men.

The present study was designed to parallel the well-established literature examining women’s responses to fashion images in terms of changes in body-image and mood …

University Counseling Center Clients' Perspective Of Their In-Session Covert Reactions: A Qualitative Study, Karissa K. Adams

Theses and Dissertations

The purpose of this qualitative study was to explore university counseling center clients’ experience and perspective of their in-session covert reactions. The Consensual Qualitative Research method was used to analyze the qualitative data. Twelve participants who were seeking services at a midsize West Coast university counseling center participated in the study. Each participant completed a telephone interview and four questionnaires (Working Alliance Inventory-Short Form, demographic questionnaire, Target Concerns Questionnaire, and the Client Feedback Form).

The qualitative analysis revealed several meaningful categories pertaining to clients’ experience and perspective of their covert reactions. All of the participants in this study reported that …

Psychological Distress Between American Indian And Majority Culture College Students Regarding The Use Of The Fighting Sioux Nickname And Logo, Angela Laroque

Theses and Dissertations

The purpose of the study was to investigate to what extent, the “Fighting Sioux” Nickname and Logo affects American Indian and Majority Culture college students emotionally. This study compared American Indian and Majority Culture students’ differences of emotional reactions and distress to twc different slide presentations using images of the “Fighting Sioux” Nickname and Logo found around the campus of the University of North Dakota (UND). The main focus was to examine the possible psychological side effects.

Participants consisted of 36 Majority Culture and 33 American Indian College students in attendance at UND. Each participant filled out an informed consent …

Why Faculty Use A Course Management System (Blackboard) To Supplement Their Teaching Of Traditional Undergraduate Courses, Lori Anne Swinney

Theses and Dissertations

Use of course management systems (CMS) in higher education has risen dramatically since their development in the late 1990s. This qualitative study investigated the use of a course management system (CMS) by faculty teaching undergraduate, traditional courses in a Midwestern liberal arts university. The focus of the study was on the reasons faculty stated for their adoption of a course management system in their course. Three faculty members were interviewed over a three-month time period. The participants in this study were not mandated to use a CMS by their department or the institution. Initially faculty members were asked questions regarding …

Thelma Daggs - Recollections Of A "Negro" Teacher At The Fort Totten Indian Boarding School: Pte Wa Uspewicakiyapi (Buffalo Teacher), Patricia R. Maggard

Theses and Dissertations

Black teachers’ unique historical experiences are often completely overlooked or amalgamated with those of White teachers in states such as North Dakota, where the population is predominantly White and the study of African Americans is particularly sparse. This study examines the life experiences of Thelma Bertha Daggs (now deceased), an African American teacher at the Fort Totten Indian Boarding School, Devils Lake, North Dakota from 1949 - 1967. Emphasis was placed on describing and understanding past events and the particular life experiences of Thelma Daggs through collection, evaluation, analysis and interpretation of data, including a range of historical sources from …

Phosphorylation Of Skeletal Muscle Acetyl-Coa Carboxylase By Ampk Enhances Palmitoyl-Coa Inhibition, Dustin S. Rubink

Theses and Dissertations

Acetyl-CoA carboxylase (ACC) catalyzes the formation of malnoyl-CoA, which in turn controls the rate of fatty acid metabolism. ACC beta or 2 has been shown to be localized on the mitochondria in close proximity to carnintine palmitoyl transferase 1 (CPT-1), the enzyme responsible for the influx of acyl-CoA into the matrix where beta oxidation takes place. CPT-1 is inhibited by malonyl-CoA produced by ACC. It has been well documented that AMP activated kinase (AMPK) when activated phosphorylates and inactivates ACC. ACC is controlled allosterically by citrate, which activates, and by palmitoyl-COA, which inhibits. In this study, we asked the question, …

Access To Learning: A Handbook For Parents, Teachers, And Paraeducators For Preschool Children With Visual Impairments, Mariah D. Thiel

Theses and Dissertations

No abstract provided.

Wind Tunnel Investigation Of The Static Stability And Control Effectiveness Of A Rotary Tail In A Portable Uav, Jose R. Rivera Parga

Theses and Dissertations

The Air Force Research Lab, Munitions Directorate, Flight Vehicles Integration Branch (AFRL/MNAV) developed a man-portable, carbon-fiber matrix UAV with a flexible rectangular wing of 24" span and 6" chord, 18.2" length. There is a need for the development of smaller and lighter UAV's to perform certain missions. The objective of this experimental study was to determine the behavior and the aerodynamic characteristics of rotary tails. The bird-inspired rotary tail mechanism studied enabled control of two degrees of freedom and was configured to provide elevator deflection and rotation. Its effects on the static stability and control effectiveness were measured using the …

Density Effects On Growth, Survival And Diet Of June Sucker (Chasmistes Liorus): A Component Allee Effect In An Endangered Species., David Barrett Gonzalez

Theses and Dissertations

Density-dependence is considered one of the most important regulators of population growth, and it has been documented across a wide variety of species. Typically, population growth rate and components thereof decline with increasing density (i.e., negative density-dependence); however, in species that exhibit high population densities and social behavior, positive density-dependence (i.e., Allee effect) may occur at low density. June sucker, a federally endangered lake sucker endemic to Utah Lake, Utah, USA, occurred historically at high density, and it exhibits coordinated feeding behavior. These characteristics indicate a potential for the existence of an Allee effect at current low population densities. To …

Effects Of Different Jumping Programs On Hip And Spine Bone Mineral Density In Pre-Menopausal Women, J. Eric Strong

Theses and Dissertations

Sixty premenopausal women (age 25-50) finished a 16 week randomized controlled trial looking at the effects of different jump programs on hip and spine bone mineral density (BMD). Subjects were randomly assigned to a control group or one of two jumping groups. The Jump 10 group performed 10 jumps with 30 seconds of rest between jumps, twice daily, while the Jump 20 group performed the same protocol but with 20 jumps. At 8 weeks, BMD percent change (%Δ) at the hip was significantly different among groups when age, weight change, and subject compliance were simultaneously adjusted. In particular, the Jump …

Intelligent, Pervasive And Context-Aware Promotion Delivery Framework For Wireless Mobile Devices, Karthik Harihar

Theses and Dissertations

Mobile devices are now powerful systems and are the main vehicles for m- commerce. Market research predicts enormous potential for m-commerce applications and services [9], [10], [11], [12]. Unique features such as portability, location-awareness and personalization make mobile devices effective tools for targeted advertising. Several mobile marketing frameworks have been designed that deliver promotions based on location information and user preferences [3], [4], [5]. These frameworks have several drawbacks that need to be addressed in order to be effective. The aim of this thesis is to research a simple and efficient framework for targeted and personalized advertising. This work presents …

Bioinformatic Analysis Of A Mammalian Bip Gene For Insertion Into Green Algae And Comparison Of Its Possible Effects On The Synthesis Of A Mammalian Antibody, Katrina Ghazanfar

Theses and Dissertations

This dissertation describes a study utilizing bioinformatics to analyze homologues of a molecular chaperone, glucose-regulated protein 78 (grp 78), also known as BiP. The selected homologous proteins originate from organisms of infinitely diverse genera. Comparisons of protein sequence yielded the first clues of a common ancestry among these proteins. Furthermore, protein molecular weights, isoelectric points, N-terminal amino acids and half-lives of a known homolog and a non-homologous protein were examined. Additionally, electroporation, a state-of-the-art plasmid insertion technique, was explored using Chlamydomonas reinhardtii, a green alga, as the recipient of a parent plasmid, pSP124S. Distinctive hypertonic solutions and three separate field …

The Benefit Of Using Simulation To Improve The Implementation Of Lean Manufacturing Case Study: Quick Changeovers To Allow Level Loading Of The Assembly Line, Jack J. Mcclellan

Theses and Dissertations

In today's competitive manufacturing environment, companies are constantly looking for ways to improve. Because of this, many companies are striving to become "lean" by implementing lean manufacturing, which is a difficult process. To aid in the implementation of lean manufacturing, simulation was used to reduce the trial-and-error period of lean manufacturing and find to optimum approach to implement the lean manufacturing principle. In this research, a case study of implementing level loading of the production schedule for BullFrog International, L.C. will be examined. To make it possible to implement level loading, the thermo-former machine at the beginning of the operations …

The Effects Of Selenium On Estrogen-Regulated Gene Expression In Lncap Prostate Cancer Cells, Tory L. Parker

Theses and Dissertations

Prostate cancer is the most frequently diagnosed cancer in American men and the second leading cause of cancer deaths. Supplementation with Se has reduced the incidence of prostate cancer and Se status is inversely correlated with prostate cancer risk. One molecular mechanism by which high Se concentrations may affect cancer risk is by catalyzing disulfide bond formation or otherwise complexing with reactive sulfhydryl groups in cellular proteins. The estrogen receptor (ER) contains cysteines in zinc (Zn) fingers that are susceptible to oxidation and internal disulfide formation, which can prevent DNA binding. We examined ER binding to its DNA response element …