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Identification And Characterization Of The Expression Profile Of Oligodendrocyte-Derived And Associated Proteins Via Unilateral X-Irradation Of The Rat Optic Nerve, Nicholas Greco Jan 2005

Identification And Characterization Of The Expression Profile Of Oligodendrocyte-Derived And Associated Proteins Via Unilateral X-Irradation Of The Rat Optic Nerve, Nicholas Greco

Theses and Dissertations

Recent studies examining cell-cell interactions during CNS development and following disease or trauma have highlighted our limited understanding of the in vivo functions of the myelinating cell of the CNS, the oligodendrocyte. With this in mind, our laboratory has developed techniques by which a profile of proteins derived from or regulated by oligodendrocytes can be elucidated. Specifically, we have demonstrated that oligodendrocytes can be selectively eliminated from one optic nerve of a rat by treating the animal with a unilateral exposure of X-irradiation at the time of birth. Consequently, this approach allowed us to experimentally create, within the same animal, …


Type-5 Phosphodiesterase Inhibition In The Prevention Of Doxorubicin Cardiomyopathy, Patrick William Fisher Jan 2005

Type-5 Phosphodiesterase Inhibition In The Prevention Of Doxorubicin Cardiomyopathy, Patrick William Fisher

Theses and Dissertations

Prior studies have demonstrated the effect of diazoxide in protecting against apoptosis via mitochondrial KATP channel opening in vitro. The current investigations are designed to determine if sildenafil, a phosphodiesterase-5 inhibitor and known mitochondrial KATP channel opener, would protect against chronic doxorubicin cardiomyopathy both in vivo and in vitro.Male ICR mice were randomized to 1 of 4 treatments: saline, sildenafil (0.7 mg/kg IP), doxorubicin (5 mg/kg IP), and sildenafil (0.7 mg/kg IP)+doxorubicin. Apoptosis was determined using the terminal deoxynucleotidyl transferase mediated dUTP nick-end labeling and in situ oligo ligation methods. Desmin distribution was determined via immunofluorescence. Bcl-2 was analyzed by …


Brownian Dynamics Simulation Of The Interaction Between Lactate Dehydrogenase (Ldh) And G- Or F-Actin, Njankwa N. Njabon Jan 2005

Brownian Dynamics Simulation Of The Interaction Between Lactate Dehydrogenase (Ldh) And G- Or F-Actin, Njankwa N. Njabon

Theses and Dissertations

No abstract provided.


Motives Behind The Use Of Visual Artifacts In Catholicism And Sunni Islam : Contribution To Discussion Of Representation, Alevtina Naumova Jan 2005

Motives Behind The Use Of Visual Artifacts In Catholicism And Sunni Islam : Contribution To Discussion Of Representation, Alevtina Naumova

Theses and Dissertations

No abstract provided.


The Effect Of Fuel Size On The Energy Density Of Producer Gas In A Biomass-Fired Modified Downdraft Gasifier, Kyle Edgar Martin Jan 2005

The Effect Of Fuel Size On The Energy Density Of Producer Gas In A Biomass-Fired Modified Downdraft Gasifier, Kyle Edgar Martin

Theses and Dissertations

No abstract provided.


Consistently Constitutional : The Development Of The Constitutional Ideology Of The American Colonies, Jeffrey C. Hart Jan 2005

Consistently Constitutional : The Development Of The Constitutional Ideology Of The American Colonies, Jeffrey C. Hart

Theses and Dissertations

No abstract provided.


The Impact Of Cloud And Radiation On The Great Plains Climate Change, Julie L. Popham Jan 2005

The Impact Of Cloud And Radiation On The Great Plains Climate Change, Julie L. Popham

Theses and Dissertations

No abstract provided.


Calcium Kinetic Studies In Animal Models For Osteoporosis Using ⁴⁷Ca/⁴¹Ca Radiotracers, Jennifer Ann Sattler Jan 2005

Calcium Kinetic Studies In Animal Models For Osteoporosis Using ⁴⁷Ca/⁴¹Ca Radiotracers, Jennifer Ann Sattler

Theses and Dissertations

No abstract provided.


Web-Based Learning : Investigating The Role Of Visual Communication Strategies Between Students And Technology, Brandon J. Semler Jan 2005

Web-Based Learning : Investigating The Role Of Visual Communication Strategies Between Students And Technology, Brandon J. Semler

Theses and Dissertations

No abstract provided.


Community Dynamics Of Terrestrial Vertebrates In Aspen Parkland-Mixed Grass Prairies Habitats At J. Clark Salyer National Wildlife Refuge In North Dakota, Neil J. Kadrmas Jan 2005

Community Dynamics Of Terrestrial Vertebrates In Aspen Parkland-Mixed Grass Prairies Habitats At J. Clark Salyer National Wildlife Refuge In North Dakota, Neil J. Kadrmas

Theses and Dissertations

No abstract provided.


The Socialization Of Religious Beliefs And Practices : An Analysis Of Laypersons In A Small Upper-Midwestern City, Paul Knudson Jan 2005

The Socialization Of Religious Beliefs And Practices : An Analysis Of Laypersons In A Small Upper-Midwestern City, Paul Knudson

Theses and Dissertations

No abstract provided.


Living Digestibility Of Alfalfa And Barley In Llamas (Lama Glama) In The Agricultural Experimental Center Condoriri, Adelaida Alarcon Chuquichambi Jan 2005

Living Digestibility Of Alfalfa And Barley In Llamas (Lama Glama) In The Agricultural Experimental Center Condoriri, Adelaida Alarcon Chuquichambi

Theses and Dissertations

The following investigation was carried out in the Agricultural Experimental Center Condoriri (CEAC), dependent on the Faculty of Agricultural Livestock Sciences and Veterinary Medicine, located to the North of the Province border of the Department of Oruro, a distance of 12 km from the town of Caracollo and 49 km from the city of Oruro. The production of llamas and alpacas in our country is an activity of ecological, social, and especially ecological importance for Andean inhabitants. In nutrition, the fundamental factor is the power of absorption; this is because the yield of animal production depends on the quantity and …


In Vivo Digestibility In Llamas (Lama Glama), Fed With Barley And Paja Brava At The C.E.A.C., Martha Jesusa Llanos Pérez Jan 2005

In Vivo Digestibility In Llamas (Lama Glama), Fed With Barley And Paja Brava At The C.E.A.C., Martha Jesusa Llanos Pérez

Theses and Dissertations

The Highlands of Bolivia present a great diversity of native botanical species with strong forage characteristics, providing them with a considerable potential for usage as a resource in the feeding of cattle. The following work was performed with the idea of taking advantage of the zone’s native species as a source for the feeding of llama cattle. In order to accomplish it, we took into consideration the following variables: food consumption, water consumption, amount of fecal excretions, urine volume, body weight, and the digestibility of the nutrients found in the food prepared with paja brava and barley (ash, protein, fiber, …


Evaluation Of The Agronomic Performance Of Six Varieties Of Peanut (Arachis Hypogaea L.) In The St. Felix Community Of The Coroico Township (Nor Yungas-La Paz), Viviana Marleni Quisbert Jan 2005

Evaluation Of The Agronomic Performance Of Six Varieties Of Peanut (Arachis Hypogaea L.) In The St. Felix Community Of The Coroico Township (Nor Yungas-La Paz), Viviana Marleni Quisbert

Theses and Dissertations

The peanut is an important crop in most countries due to its industrial, nutritional, and pedological potential. It grows well in subtropical areas. This study was planned based on the weather characteristics of the Yungas and the St. Felix community. A completely randomized block design with 6 treatments and 3 repetitions was used. An analysis of variance and a Tukey test were used for statistical analysis of the variables. With respect to time required for maturation, the Coloradito Palmar variety was most premature with a time of 134 days while the Local variety took 177 days to mature, which is …


Brucellosis In Alpacas (Lama Pacos) In Communities Of The City Ulla Ulla, Franz Tomayo Province, Department Of La Paz, Macario Suxo Blanco Jan 2005

Brucellosis In Alpacas (Lama Pacos) In Communities Of The City Ulla Ulla, Franz Tomayo Province, Department Of La Paz, Macario Suxo Blanco

Theses and Dissertations

This investigation was performed in the Altiplano Altoandino sub-humid region in the Ulla Ulla district, Pelechuco township, Franz Tomayo province, department of La Paz, Bolivia. The objective of this study was to quantify and compare the presence of Brucellosis in male and female alpacas (Lama pacos) at ages 2, 3, 4, 5, 6, and 7 years. Blood samples were taken from the jugular vein of 500 alpacas from the Hichucollo, Huacuchani, Ucha Ucha, and Ulla Ulla communities. The serum from each sample was separated and a serological diagnosis was performed by rapid agglutination with Rose Bengal chemical stain. In the …


Replacement Of Fish Meal By Meal Worm (Eisenia Foetida) In The Feed Of Broilers As An Alternative Source Of Protein, Carlos ÁNgel Cervantes Cevallos Jan 2005

Replacement Of Fish Meal By Meal Worm (Eisenia Foetida) In The Feed Of Broilers As An Alternative Source Of Protein, Carlos ÁNgel Cervantes Cevallos

Theses and Dissertations

This investigation was conducted in the rural community of Cuambo, located in the northeast of Imbabura province, in the Mira river basin of Salina parish, at 1530 meters above sea level and with an average temperature of 19 C. The principal objective of this investigation was to evaluate the effect of four levels of substitution of fish meal for earthworm meal in broiler chicken diets. The fieldwork occurred in two stages over the course of 20 months: A. Creation of the feed: This step lasted from the installation of an earthworm culturing area through the cultivation, harvest, and drying of …


Biochemical And Molecular Nutrition Blocks As Dietary Supplements In Llamas (Lama Glama) In The Last Third Of The Gestation Period Of The Ceac, Janette Illanes Callejas Jan 2005

Biochemical And Molecular Nutrition Blocks As Dietary Supplements In Llamas (Lama Glama) In The Last Third Of The Gestation Period Of The Ceac, Janette Illanes Callejas

Theses and Dissertations

The present work consisted in the use of biochemical and molecular nutrition blocks (BMN) in llamas during the last third of the gestation period, at the Agricultural Experiment Center of Condori (CEAC), located 49 km north of the city of Oruro, and 12 km north of the Caracollo population, in the province of Cercado. For this research work, we used 20 pregnant llamas in the last third of their gestation period, between the ages of 2 and 3 years old, 10 of which belonged to the Khara breed, and 10 to the Thampulli breed. Two corrals of 7 x 7 …


Agronomical Evaluation Of Six Species Of Forage Grass Tolerant To Salinity In The Tamborada Region, Bladimir Vargas Rojas Jan 2005

Agronomical Evaluation Of Six Species Of Forage Grass Tolerant To Salinity In The Tamborada Region, Bladimir Vargas Rojas

Theses and Dissertations

Six forage grass species from the United States were evaluated for salinity tolerance and growth performance. A randomized block design was used with six repetitions of five furrows each to maintain experimental consistency. The study was conducted in the Tamborada region of Cochabamba, Bolivia from December 2003 through June 2004. Results indicated that significant differences exist between species (Pr<0.01). The species Elymus cinereus and Agropyron elongatum demonstrated the best performance regarding plant height, achieving heights of 35.4 cm and 32.7 cm respectively. Festuca arundinacea and Agropyron elongatum obtained larger percent coverage than the other species with 79.59% and 76.53% respectively. These species also exceed the others in production of green forage (1500.00 kg/ha and 13985.80 kg/ha) as well as in production of dry matter (5000.70 kg/ha and 4862.85 kg/ha). They are recommended for production in the region of Tamborada, Cochabamba, Bolivia.


Behavioral Social Skills Training : An Evaluation Of Adding A Concurrent Parent Training Group, Matthew P. Myrvik Jan 2005

Behavioral Social Skills Training : An Evaluation Of Adding A Concurrent Parent Training Group, Matthew P. Myrvik

Theses and Dissertations

No abstract provided.


Magic Mountain, Diana Al-Hadid Jan 2005

Magic Mountain, Diana Al-Hadid

Theses and Dissertations

My installations are propositions for an imaginary world that relies on its own internal logic, a world of believability without recognition. While the work references landscape it also emphasizes its contrivance, as it is automatically estranged in an "unnatural" gallery setting. I subvert or de-familiarize the materials and processes that I use in the service of creating a fictitious environment. My places are impossible places. They are irregular, illogical, and unstable. Our imagination can be one of most dangerous things to psychological stability as it is an inventory of all things possible, no matter how irrational or improbable. The irrational …


Global Discontents, Priyadarshini A. Khatri Jan 2005

Global Discontents, Priyadarshini A. Khatri

Theses and Dissertations

My creative project explores toys as means to express economic issues of globalization. By exploiting the educational and imaginative aspects of toys for adults and children, I intend to reflect on the impact and pressures of globalization on employment, technology and environment. In creating these toys I hope to make a visual statement concerning critical issues of human survival, sustainability and the divisive side of globalization.


Long-Term Cardioprotection With Phosphodiesterase-5 Inhibition Against Ischemia-Reperfusion Injury: Role Of Nitric Oxide., Vladimir Paul Daoud Jan 2005

Long-Term Cardioprotection With Phosphodiesterase-5 Inhibition Against Ischemia-Reperfusion Injury: Role Of Nitric Oxide., Vladimir Paul Daoud

Theses and Dissertations

Recent studies have shown that the potent phosphodiesterase-5 (PDE-5) inhibitor, sildenafil citrate, induces a powerful cardioprotective effect against ischemia-reperfusion (I/R) injury in rabbit and mouse hearts. However, the effect of this drug in inducing long-term protection against I/R injury remains unknown. The goal of this study was to identify the duration of the protective window of sildenafil citrate as well as vardenafil, a more potent PDE-5 inhibitor. Rabbits were treated with sildenafil (0.7 mg/kg, iv), vardenafil (0.143 mg/kg), or an equivalent volume of saline. After 24 hrs, 48 hrs, 96 hrs, or 7 days of sildenafil treatment, the hearts were …


Novel Strategies In Cardioprotection Against Ischemia/Reperfusion Injury, Fadi N. Salloum Jan 2005

Novel Strategies In Cardioprotection Against Ischemia/Reperfusion Injury, Fadi N. Salloum

Theses and Dissertations

Cell damage represents a major pathomechanism in many diseases of high clinical interest, such as myocardial infarction (MI), where it plays an important role in ischemia-reperfusion (I/R) injury. Considerable progress has been made towards identifying physiological and pharmacological agents that play a key role in myocardial preconditioning against I/R injury and also elucidating the molecular changes leading to such protection.Second messengers in cellular signaling pathways, such as cGMP have been well implicated as key players in ischemic and pharmacological preconditioning (PC) of the heart. Phosphodiesterase type 5 (PDE-5) is an enzyme that specifically hydrolyzes cGMP thereby decreasing its tissue concentration. …


Interleukin-10 Induces Apoptosis In Developing Mast Cells Via A Mitochondrial, Stat3-Dependent Pathway, Daniel Paul Bailey Jan 2005

Interleukin-10 Induces Apoptosis In Developing Mast Cells Via A Mitochondrial, Stat3-Dependent Pathway, Daniel Paul Bailey

Theses and Dissertations

Objective. The aim of this study was to determine the effects of interleukin-10 on mast cell development from bone marrow progenitors.Materials and Methods. Unseparated mouse bone marrow cells were cultured in IL-3+SCF, giving rise to mast cells and monocytes/macrophages. The addition of IL-10, and the use of Signal Transducer and Activator of Transcription (STAT)3-deficient bone marrow cells were employed to measure the effects of IL-10 and STAT3 expression on cell viability, proliferation, and differentiation. Bax-deficient and Bcl-2 transgenic bone marrow cells were used to determine the importance of the mitochondria in IL-10-mediated effects.Overview. Mast cells arise from hematopoietic stem cells …


Real Time Frequency Analysis Of Signals From Lasso Catheter For Radiofrequency Ablation During Atrial Fibrillation, Prashant Yadav Jan 2005

Real Time Frequency Analysis Of Signals From Lasso Catheter For Radiofrequency Ablation During Atrial Fibrillation, Prashant Yadav

Theses and Dissertations

Real time spectrum analysis of signals obtained through lasso catheter during radiofrequency ablation of pulmonary vein was performed to determine the channel with dominant frequency. Threshold algorithm was used for signals which could be classified as type I and type II AF. Type III AF Signals which were highly fractionated or differentiated were evaluated for frequency content by performing Fast Fourier Transform. Data from Seven patients was collected and an episode of 180 ± 40 seconds was recorded and analyzed for each pulmonary vein that showed electrical activation. Frequency spectra for one second segment of signal for each channel were …


Effect Of The Use Of Amaranth (Amaranthus Spp.) Leaf Flour In The Creation Of Feeds For The Production Of Broiler Chickens, Wendy Valeria Quel Ruíz Jan 2005

Effect Of The Use Of Amaranth (Amaranthus Spp.) Leaf Flour In The Creation Of Feeds For The Production Of Broiler Chickens, Wendy Valeria Quel Ruíz

Theses and Dissertations

This investigation was conducted in the rural community of Cuambo, located in the northeast of the province of Imbabura, in the Mira river basin of Salinas parish, at 1530 meters above sea level and with an average temperature of 19.5° C. The main objective of this investigation was to analyze the effect of using amaranth (Amaranthus) leaf flour in the creation of feeds for broiler chickens. The field work occurred during 12 months and consisted of two phases: A. Creation of the feed: This proceeded from the cultivation, cutting, and drying of amaranth until the obtaining of the flour and …


Long-Term Consequences Of West Nile Virus In Virginia., Diana Cruz Ocampo Jan 2005

Long-Term Consequences Of West Nile Virus In Virginia., Diana Cruz Ocampo

Theses and Dissertations

Objective: The purpose of this investigation was to describe the long-term effects and functional outcomes of patients in Virginia who were reported to the Virginia Department of Health with West Nile virus (WNV) non-neuroinvasive and neuroinvasive disease. The study identified the duration of symptoms after initial illness, the number of persons who fully recovered versus the number who continue to be symptomatic and how patients' quality of life differed after illness.Methods: The study population was drawn from 60 human cases that met the surveillance case definition for non-neuroinvasive and neuroinvasive WNV illness in Virginia between 2002-2004. Information was collected during …


Population Ecology Of White-Tailed Deer In The Drift Prairie-Coteau Of North Dakota, Jason R. Smith Jan 2005

Population Ecology Of White-Tailed Deer In The Drift Prairie-Coteau Of North Dakota, Jason R. Smith

Theses and Dissertations

No abstract provided.


Avian And Vegetative Diversity Of Restored And Natural Basin Wetlands In East Central North Dakota, Blane A. Klemek Jan 2005

Avian And Vegetative Diversity Of Restored And Natural Basin Wetlands In East Central North Dakota, Blane A. Klemek

Theses and Dissertations

No abstract provided.


Hyperventilation And Its Effects On The Neurosurgical Patient, Melissa L. Laspi Jan 2005

Hyperventilation And Its Effects On The Neurosurgical Patient, Melissa L. Laspi

Theses and Dissertations

No abstract provided.