Digital Commons Network^™

Evaluation Of Rotenone Mediated Α-Synuclein Spreading And Neurotoxicity In Intra-Striatal Injection Of Α-Synuclein Pff Model Of Parkinson’S Disease, Engila Khan

Theses

In the last 25 years, the prevalence of Parkinson’s Disease (PD) across the globe has doubled. Clinical manifestations of this progressive neurodegenerative disorder include motor symptoms such as tremors, bradykinesia, postural instability, etc., which occur due to selective loss of dopaminergic neurons in the Substantia nigra (SNC) in the brain. The histopathological feature of PD is the presence of intra-neuronal aggregates of proteins called Lewy bodies, a major constituent of which is α-synuclein (α-syn).

Epidemiological studies to date have reported a connection between exposure to environmental neurotoxins such as Rotenone (a mitochondrial complex 1 inhibitor) and increased risk of PD …

Development Of A Vortex-Cooled Bipropellant Thruster And Evaluation Of Performance Characteristics With Respect To Injection Parameters, Mousa Adnan Aqailan

Theses

This study presents an experimental assessment of the cooling performance and efficiency of a 10N-vortex-cooled Propane/Gox bi-propellant thruster that was fabricated using metal and thermoplastic material. The proposal of injecting an oxidizer in a vortex pattern was suggested as a potential cooling method for semi-thermoplastic constructed thrust engines. This method has been demonstrated as a promising candidate for integrated cooling and can be manufactured using 3D printing technology. In contrast to typical complicated cooling systems and their attributed common downsides; the vortex injection can be 3D printed as a single solid piece thruster, thereby reducing design complexity, weight, and manufacturing …

Electromagnetic Mems Safety And Arming Devices, Fatima Rashed Alnuaimi

Theses

This thesis aims to investigate the design of safety and arming devices within artillery fuzes, which rely on the spin velocity and setback acceleration of the weapon. These systems consist of two critical components: the spin lock and the inertia lock. The spin velocity and setback acceleration of the weapon induce deformations in these components, serving as key criteria for determining whether the weapon is in an armed or safe state.

The primary objective of this thesis is to comprehensively analyze and assess the design of both the spin lock and inertia lock. The research will delve into multiple factors …

Population Structure And Genetic Diversity Of The Socotra Cormorant (Phalacrocorax Nigrogularis), Noura Mabkhout Almansoori

Theses

The Socotra cormorants (Phalacrocorax nigrogularis) are regional endemic seabirds restricted to the Arabian Gulf, Gulf of Oman, and the Arabian Sea. This species is classified as vulnerable by the IUCN Red List. However, no population genetic study has been conducted on P. nigrogularis in their range, and population structure, gene flow and connectivity between colonies is unknown. Likewise, genetic diversity of this species has not yet been characterized. Thus, the aim of this thesis was to fill these gaps by inferring population structure, assessing gene flow and genetic diversity of Socotra cormorant colonies in their known distribution range. …

Prevalence, Knowledge, Attitude, And Practice Of Dietary Supplement Use Among Students Enrolled In The United Arab Emirates University, Aaesha Hamad Alnaqbi

Theses

An adequate diet, with proper nutrients, is key to a healthy life. However, managing an adequate diet with a proper intake of nutrients is difficult. Therefore, dietary supplements (DS) represent an important source of essential nutrients which often help maintain a healthy intake of required nutrients. However, there is limited knowledge about DS usage among the younger generation. The main objective of this research study was to analyze the prevalence of usage, level of knowledge, and attitudes toward DS among Students enrolled in the United Arab Emirates University. The current research adopted a cross-sectional design. Participants completed a valid and …

The Association Between Total And Types Of Dietary Protein Intake And Prevelence Of Impaired Fasting Glucose And Type 2 Diabetes, Afra Salah Alsammach

Theses

People with impaired fasting glucose (IFG) and type 2 diabetes (T2D) need to modify their dietary composition. This could assist in the management and prevention of the disease. However, the role played by the composition of specific dietary macronutrients on the risk of IFG & T2D needs further research. This study sought to examine the association between total and type of dietary protein (animal and plant) consumption with prevalence of T2D and IFG. Aims: To investigate the association between total intake and types (animal vs plant) of dietary protein intake and prevalence of IFG & T2D in adults. Data …

Data Sharing And School Improvement: A Phenomenological Study Of Source, Mechanisms, Lacunes And Usefulness, Maitha Khalifa Al Mansoori

Theses

This study aimed to gain a better understanding of the datafication process and determine whether it contributes to school improvement in public schools. A particular focus was placed on investigating the methods used in data collection from various sources, the mechanisms in place for data sharing, the ways in which data are collected and shared, the gaps in data sharing, and the ways in which school administrators and teachers are sharing data for the school improvement. The use of a transcendental phenomenological approach contributes to the development of a theoretical model that illustrates how school data sharing works and how …

Modulation Of Chronic Allergic Contact Dermatitis Through B Cells, Sara Saeed Alhmoudi

Theses

Allergic contact dermatitis (ACD) is a common inflammatory disease caused by contact with an allergen and is a T-cell-mediated type IV hypersensitivity reaction. Shortchain fatty acids (SCFAs) showed the ability to modulate immune cells in case of inflammation. Pentanoate is one of the abundant SCFA that showed therapeutic ability by inducing interleukin-10 (IL-10) secretion in lymphocytes. IL-10-producing regulatory B cells have been shown to decrease different inflammatory responses; however, the overall role of B cells in ACD is not well studied. This project aims to explore the role of B cells during chronic ACD and their modulation with the SCFA …

Modification Of Cellulose Fibers By Acyl Grafting For Oil Spill Remediation, Fatima Saif Alhumaidi

Theses

Oil spills represent a significant source of aquatic pollution with substantial repercussions on the environment as well as the economic and societal well-being of coastal communities. This research project is focused on the utilization of chemically modified cellulose-based fibers to remediate oil-contaminated water. The hydroxyl groups present in cellulose were acetylated under optimized conditions, thereby rendering the fibers hydrophobic and enhancing their affinity for crude oil. The modified cellulosic material was characterized by several physical and chemical techniques (IR, TGA, contact angle measurement, SEM, and back titration) to determine the extent of acylation and assess their morphological properties. The derivatized …

The Association Between Added Sugar And Abdominal Obesity In Adults, Noora Salem Alhammadi

Theses

Excessive body fat accumulation is a complicated medical condition known as obesity. Obesity increases the risk of chronic diseases including type 2 diabetes mellitus, cardiovascular disease, and several types of cancer. Numerous studies have shown that adults who regularly consume added sugar, mostly from sugar sweetened beverages, are more likely to be overweight or obese and/or abdominal obesity, however results remain controversial. The primary objective was to evaluate the relationship between Greek adults’ consumption of added sugar and abdominal obesity. The primary outcome was to investigate the intakes of added sugars in relation to weight status, fat mass, and specific …

Development Of Popcorn Thermal Insulation Panels, Yonis Hussein Mohamud

Theses

The research and development of sustainable and renewable materials that can take the place of conventional plastics derived from petroleum has attracted increasing attention in recent years. Polylactic acid (PLA) and Polyhydroxy butyrate (PHB) are viable alternatives biopolymers due to their biodegradability. Also, the enhancement of material properties can be achieved through the incorporation of fillers. In this study, the utilization of popcorn in developing of insulation materials has been employed in two distinct methodologies. The first involves the coating of popcorn with varying percentages of PLA using the solvent casting method, while the second involves the integration of popcorn …

Investigating Bim Applications In Reducing Co2 Emissions In The Built Environment – Uae Context, Rua Ahmed Maali

Theses

Large amounts of CO₂ are released into the atmosphere throughout the life cycle of a building starting from the production of materials and products, in the construction phase of the building itself, in the site setting, the renovations, the later rehabilitation, and up to the final demolition. Hence, this thesis aims to investigate the potential of using Building Information Modeling (BIM) in making informed decisions that can help in reducing CO₂ emissions in the life cycle of built environment projects. This study has used a mixed method approach that includes literature review, a case study and semistructured interviews. …

Design And Fem Modelling Of Mems Capacitive Accelerometer And Gyroscope For Quadcopter/Uav Applications, Shaikha Rashid Alnaqbi

Theses

This study presents the design, simulation, and analysis of Micro Electromechanical Systems (MEMS) sensors, constituting the principal components of MEMS-based Inertial Measurement Units (IMUs). The main objective of the study is to design, simulate and analyze 3-axis capacitive accelerometer and 3-axis gyroscope. The MEMS-based capacitive accelerometers and gyroscope are analyzed using Ansys Workbench. Modal, Static Structural and harmonic analysis are used to obtain resonant frequencies, deformation/stress and profile of amplitude over a wide range of frequencies. Mechanical sensitivity analysis of the designed accelerometer and gyroscope is performed using the Finite Element Method (FEM). Analytical Equations are developed to calculate mechanical …

Examining The Relationship Between Help-Seeking Behaviors, Mental Health Perceptions, And Preferred Modality Of Therapy Services Among University Students In Arab Countries: A Comparitive Study, Roxanne Wolmarans

Theses

As mental health concerns continue to grow in the modern world, many are faced with barriers to seeking help due to attitudes, beliefs and self-stigma. This is especially true within Arab cultures. The main objective for this study was to examine how these attitudes, beliefs and self-stigma may impact a person’s help seeking behavior’s when compared to a preferred modality of treatment, namely online and face-to-face therapy. A cross-sectional study using online surveys consisting of the Self-Stigma of Seeking Help Survey (SSOSH), the Attitudes Toward Seeking Professional Psychological Help Scale - Short Form (ATSPPH - SF), the Online Counselling Attitude …

An Empirical Study On The Use Of Secure Predictive Analytics For Improving Trade Forecasting In The Uae, Asma Salem Alneyadi

Theses

Trade contributes to the United Arab Emirates' economic growth. This thesis focuses on trade dynamics in the UAE using Long Short-Term Memory (LSTM) neural networks. The study focuses on both import and export activities, providing understandings into the complex patterns and impacts of international trade on the UAE's economic growth. The research begins by constructing an LSTM model to forecast the UAE's Gross Domestic Product (GDP) through the utilization of historical trade data. We use time series data for imports and exports as key input features. This innovative approach highlights the relevance of trade statistics as a leading indicator of …

Radio Emission From Low-Mass Active Galactic Nuclei, Ammara Aftab

Theses

Massive black holes of a few million to billion solar masses lurk at the centers of the most present-day massive galaxies but their origin is still unknown. The low mass galaxies (M* ~ 3x10⁹ Mʘ ) hosting black holes with masses ranging from 10³ to 10⁵ Mʘ are ideal laboratories to test the models of black hole formation and they may help in understanding the co-evolution of central black holes with their host galaxies. In this thesis, we have developed a detailed theoretical model/framework to estimate the radio emission from low-mass active galactic nuclei (AGN). We also …

Anti Cancer Activity Of Rhus Coriaria (Sumac) Against 5-Fluorouracil-Resistant Colorectal Cancer Cells, Zohra Nausheen Nizami

Theses

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths, both worldwide and in the UAE. 5-Fluorouracil (5-FU), a pyrimidine analogue, is a chemotherapeutic agent that is an integral component of chemotherapy regimens for CRC treatment. However, 5-FU resistance (intrinsic and/or acquired) inhibits their clinical efficacy. In recent years, there has been a growing popularity for plant-based cancer therapeutics, specifically using phytochemical compounds. Rhus coriaria (Sumac) is a Mediterranean plant whose fruits are used as a spice and medicinal herb. Extracts of Rhus coriaria fruits (RCE) have been reported to exhibit anti-cancer activity against breast cancer and CRC. In …

Exploring Food And Physical Activity Behaviours Of Adolescents After Bariatric Surgery: A Qualitative Study, Baraa Osama Alries

Theses

In recent years, both globally and in the United Arab Emirates, adolescent obesity has emerged as a severe public health concern. Bariatric surgery is a viable treatment for adolescent obesity. However, an equally important aspect is examining the lifestyle changes, specifically concerning dietary habits and physical activity after this surgical intervention. Moreover, there is limited research on the postoperative nutrition-related nutritional and physical activity behaviors of adolescents after bariatric surgery globally, regionally, and in the UAE. The main aim of this study was to explore barriers and facilitators of diet and physical activity regimens of adolescents who had undergone bariatric …

Assessing Asset Management In Aec/Fm: Unveiling Limitations And Advancing Solutions With Digital Twin, Abdelmoneim Mohamed Abdelmoti

Theses

In recent years, the concept of Digital Twins (DTs) has emerged as a transformative technological innovation with the potential to revolutionize asset management practices. A Digital Twin is a digital representation closely linked to a physical entity, enabling bidirectional information exchange and data-driven decision-making. Within the realm of Architecture, Engineering, and Construction/Facilities Management (AEC/FM), DTs offer a diverse array of applications for enhancing asset management.
/="/">This thesis aims to demystify the concept of DTs and explore their existing applications in asset management, particularly within the AEC/FM industry. To achieve this, the research employs a two-fold approach: a systematic review …

Experimental Study Of Central And Side Jet With And Without Chevron Nozzle Exit On Gas Turbine Leading Edge Jet Impingement Cooling, Ahmad Yousef Alqasrawi

Theses

This thesis presents a comprehensive investigation into the application of jet impingement cooling on turbines blade leading edge. Gas turbines are extensively utilized in power generation and aerospace industries, where efficient cooling techniques are crucial to enhance the performance and lifespan of turbine blades. The leading edge of a turbine blade is particularly vulnerable to high-temperature exposure and thermal stresses, making it an essential area for effective cooling strategies. Jet impingement cooling is one of the most effective cooling techniques mostly used in the leading edge of rotating and stationary blades. This study aims to explore the performance of jet …

Commissioning Of The Uaeu Radio Array And Pilot Low-Frequency Radio Astronomy Studies, Aisha Ali Alnaqbi

Theses

As part of the UAEU Radio Astronomy Pathway Project, a 256-element Ground based Radio Array Facility was deployed at the UAEU. A comprehensive exploration of radio astronomy, and investigations on existing radio arrays, emphasizing low-frequency radio signals and the challenges faced at this range, are crucial for the commissioning phase of the array. A core aspect discussed is the vital role of coaxial cables in preserving the integrity of low-frequency radio signals. To address the electrical length differences between the coaxial cable pairs used to connect the array’s beamformers in the field to the beamformer controllers in the control room, …

An Examination Of The Association Between Sleep Quality And Psychological Distress Among University Students In The Middle East: A Cross-Sectional Correlational Study, Ayesha Saeed Alsuwaidi

Theses

Literature reviews have revealed that there are limited studies on sleep quality in the United Arab Emirates (UAE) and that few studies are available in the Middle Eastern region. The objective of this study was to examine the association between sleep quality and psychological distress among university students in the Middle East. A correlational cross-sectional design was determined, and a self-administered online questionnaire was used. The electronic survey was circulated amongst students on campus and received 435 responses from three universities namely, Menoufia University in Egypt, Sultan Qaboos University in the Sultanate of Oman, and United Arab Emirates University in …

The Association Between Attachment Styles And Binge Eating Behaviours: Examination Of The Mediational Role Of Emotional Dysregulation In The Arab Region, Diala Kassab

Theses

Many factors are said to affect binge eating behaviours, one of these factors is the individual’s attachment style. Attachment styles is the early relationship that shape a child's ideas and expectations about themselves and the availability of other people. This can be mediated by the ability to effectively respond and manage emotional experiences. This thesis aimed to examine the role of emotional dysregulation on attachments styles and binge eating behaviours in the Arab region.
/="/">A sample of 326 Arab university students, predominantly Emirati and Lebanese, were recruited using convenience sampling and snowball sampling technique. Participants were asked to complete …

Estimating Mars Surface Wind Stress And Dust Lifting Using Reanalyses Based On Emm And Other Spacecraft Observations, Haneen Abouhaligah

Theses

Studying Mars offers insights into terrestrial planet evolution and informs future human expeditions. This thesis examines dust dynamics in Mars’ lower atmosphere, focusing on understanding its weather and climate. We investigate the role of Near-Surface Wind Stress (NSWS) in dust lifting, using six reanalysis datasets, respectively: MACDA, EMARS, OpenMARS, ACS–TIRVIM (ExoMars observations of the MY34 Global Dust storm), EMM1 and EMM2. Following the parameterization approach by Newman et al. (2002a), areas of agreement and discrepancy among datasets were identified. Time series analysis revealed consistent results where datasets overlap temporally. Some differences were expected and shown due to the different Global …

Irritable Bowel Syndrome, Eating Disorders, And Mental Stress Among United Arab Emirates University Students, Maram Braikan Alotaibi

Theses

Irritable Bowel Syndrome (IBS), Eating Disorders (EDs), and mental stress are understudied in the United Arab Emirates (UAE), especially among university students. The objective of this study is to assess the prevalence of IBS, ED, mental stress, their associations, and the determinants of IBS among United Arab Emirates University (UAEU) students. An observational cross-sectional study was conducted via a 48-item online-survey shared with 14,268 undergraduate/graduate students, registered during academic year 2021-2022 in UAEU. Logistic regression models were performed to examine the predictive factors associated with IBS among UAEU students in total and by ED status. Significance was determined at p< 0.05. The prevalence of IBS was 39%, ED 55.9%, and high mental stress 53.2%, and they co-existed in 15.9% of UAEU students. Students who reported consuming trigger-food were 6 times more likely to have IBS than their counterpart [AOR: 5.859; 95% CI: 3.092–11.102, p< 0.001]. Those who reported intakes of relief-food were 4 times more likely to have IBS compared to their counterpart [AOR: 3.881; 95% CI: 1.669 – 9.022, p=0.002]. Students with family history of IBS (FHIBS) were 2.6 times more likely to have IBS than their counterpart [AOR: 2.572; 95% CI: 1.420–4.660, p= 0.002]. Students with high mental stress were 1.7 times more likely to have IBS than those with low-moderate stress, when adjusted for sex and age [AOR:1.730; 1.058–2.830, p= 0.029). No significant associations existed between IBS and ED, Socioeconomic Characteristics (SEC), lifestyle, dietary, and health-related factors. UAEU students reported high prevalence of IBS, ED and mental stress. A significant relationship was found between IBS and FH-IBS, trigger- and relieving- food. This study confirmed the prevalence of IBS, ED and mental stress. Large cohort studies on university students in the UAE are warranted to establish the relationships among IBS, ED, mental stress and their determinants.

Canagliflozin Ameliorates Autistic-Like Features And Mitigates Brain Oxidative Stress Levels In Valproic Acid-Induced Autism In Rats, Mohammad Moutaz Nakhal

Theses

Autism spectrum disorder (ASD) is a neurodevelopmental disease with a substantially increasing incidence rate. It is mainly characterized by repetitive behavior, intellectual difficulties, social communication and interactions deficits. Many medications, dietary supplements, and behavioral treatments have been recommended for ASD management, however, there is no cure yet. Recent studies have examined the therapeutic potential of the sodium-glucose cotransporter 2 (SGLT2) inhibitors in neurodevelopmental diseases, based on their proved anti-inflammatory and antioxidant effects. The main objective of this study is to assess the ability of canagliflozin in improving the behavioural characteristics of autistic rats and investigate the efficacy of canagliflozin in …

التنظيم القانوني للرهن التأميني للمركبات في القانون الإماراتي, عبيد محمد الكعبي

Theses

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Legal Regulation of Insurance Mortgage for The Vehicles in UAE Law

The mortgage that applies to vehicles is the insurance mortgage, because of the special nature movables have the property of self-identification, which leads to apply the registration rule on the ownership deed. The insurance mortgage is concluded between the mortgagee, who is the creditor, and the mortgager, who is either the debtor himself or someone else (the in-kind guarantor). In order for this contract to be validly concluded, it must fulfill all its elements and conditions. The objective conditions stipulated in the general rules for concluding contracts must …

Maladaptive Daydreaming And Social Anxiety: Prevalence And The Mediating Role Of Emotional Regulation, Riffa Fathima Abuthahir

Theses

Previous studies have generated mixed evidence regarding the magnitude of the prevalence of Maladaptive Daydreaming (MD). In addition, although previous studies have identified an association between Maladaptive Daydreaming (MD) and Social Anxiety (SA), literature is sparse in exploring the underlying factors such as emotional regulation difficulties that might mediate this relationship. The current study attempted to investigate the prevalence of MD and self-perceived levels of Social Anxiety (SA) among undergraduate students in the United Arab Emirates (UAE). It also attempted to explore whether difficulties in regulating emotions mediate the relationship between MD and self-perceived levels SA. A cross-sectional design with …

Chaotically-Disengaged Family Functioning And Depressive Symptoms In Muslim University Students: The Mediating Effect Of Psychological Flexibility And Self-Compassion, Sabina Ioana Varga

Theses

Depression is one of the most prevalent mental health issues among university students. Growing evidence suggests an association between impaired family functioning and increased depressive symptoms. However, there is a gap in the literature with regards to the factors that mediate this relationship. Psychological flexibility and self-compassion are two factors that have been previously linked to both family functioning and depressive symptoms. The present study aims to investigate the mediation role of psychological flexibility and self-compassion on the association between chaotically-disengaged family functioning and depressive symptoms in Muslim university students. Whilst previous studies have been conducted in this topic area …

Exploring The Relationship And Impact Of Islamic Religious Coping On The Meaning Made Following The Loss Of A Loved One, Yara Ihab Am Ali

Theses

Coping after a loss of a loved one can play out differently for different individuals. The existing literature examines coping with loss and bereavement, but it is often with specific types of loss, and usually with western populations or religions. This paper examines the impact of Islamic religious coping onto the meaning made (integration of stressful event) following the loss of a loved one to death, in a diverse ethnic background sample population of various Muslims who have experienced loss in the past 5 years. The study focuses specifically on positive religious coping, and whether it would have a positive …