Digital Commons Network^™

Development Of Nanoelectrodes For Electrochemical Applications, Séan Barry

Theses

The demand for direct, selective and rapid determination of chemical and biological analytes has led to a growing interest in electrochemical sensor devices. Particularly the use of nanomaterials and nanoelectrodes has received increased interest due to their enhanced electrochemical properties. In this thesis these enhanced properties are exploited in order to develop multiple sensing applications.

Firstly a sensitive microband based sensor is described for the detection of trinitrotoluene and for its discrimination from other nitroaromatic compounds. Square wave voltammetry was used to identify characteristic reduction peaks for these compounds and a calibration plot for the quantification of TNT was also …

Compute Or Not To Compute?, Rowena Keaveny

Theses

The primary purpose of this enquiry is to explore the relevance of digital culture to contemporary art therapy practice in the digital age. The explosion of digital media into everyday life, as evidenced through it's impact on modes of communication and transformative societal behaviours has vastly altered how humans relate to each other and the world in which they can now live both physically and virtually in what has become known as the digital age. Silhouetted by it's emergent use within the therapeutic setting and informed by current literature, articles, research, questionnaires and interviews, this enquiry seeks to address the …

Investigation Of The Natural Bacteriocin Nisin And Bioengineered Nisin Derivatives For The Prevention And Control Fo Staphylococcus Biofilms On Medical Device Materials, Leanne Kearney

Theses

Antimicrobial resistance has evolved into being one the major threats facing clinical environments worldwide. It has led to the deerease in effective prevention and treatment of pathogenic bacteria. One such bacterium is Staphylococcus epidermidis. Once considered a relatively harmless and commensal baeterium, it has recently evolved into being one the leading eauses of nosocomial infections. S. epidermidis has proven hamiful due to its ability to fonn detrimental biofilms. Biofilms are structured eonsortia of bacteria embedded in a self-produced polymer matrix that allows adherence to biotic or abiotic surfaces. These biofilms have played a leading role in healthcare-acquired infections with particular …

An Investigation Into Improving Men's Access To Health Services, Kieran Geary

Theses

This thesis sets out to examine the area of men’s health and to recommend strategies for mainstream health services to get more men interested in their health. In Ireland, men die, on average, approximately five years younger than women and have higher death rates than women for most of the leading causes of death (Richardson and Carroll, 2008). As Wilkins (2009) points out, identifying the problems with men’s health is not the ultimate challenge, nor is advocating for change at a political or policy level, rather it is identifying what works with men and translating that into workable strategies capable …

An Investigation Of The Use Of Natural Agents To Control Mycobacteria, Olga Lesniak

Theses

Economic losses that are caused by Mycobacterium avium paratuberculosis (MAP) infections represent a major obstacle for farmers and also for the dairy industry. In order to control the population of MAP, alternative control agents must be investigated. One of the studies described in this thesis focused on using a bacteriophage therapy based approach to assess its efficacy on simulated industrial environments and food models. Another study described in this thesis investigated the antimicrobial effects of parsley and garlic on a range of mycobacteria species. Both studies used conventional microbiological methods such as plaque assays, AlamarBlue assay (MABA) and growth curves, …

An Exploration Of The Smart Cities Concept: The Case For The Cork Region, Marguerite O'Connor

Theses

The term “Smart City” has gained a lot of attention from policy-makers, business leaders and citizens in recent years. The definition of what a smart city is differs depending on the city, region or individual that you ask but most definitions define it as local governments’ projects and initiatives that are implemented through some form of information and communication technologies, which are designed to enhance the quality of life for citizens and stakeholders whilst maintaining a sustainable future. This study aims to build an understanding of what the Smart cities concept actually means to Cork and the implications of Information …

Beneficial Reuse Of Marine Sediment, Sinead Tangney

Theses

Dredging is essential for ports and harbours to maintain navigational access. In Ireland approximately 1.2 million m^ is dredged annually and the management of this dredged sediment is an ongoing issue. This thesis investigates the management options available for marine dredged sediment and examines the technical, environmental and economic feasibility and social acceptability of a range of specific beneficial uses of marine sediment.

A literature review is presented on the international dredging industry and outlines why dredging is an essential infrastructural activity. Current dredged marine sediment management techniques are presented and discussed.

An overview of the Irish dredging industry is …

Activating Social Entrepreneurship Opportunities In The Youth Sector, Oliver Fahey

Theses

This study is an action research that has been conducted with the collaboration of the Kerry Diocesan Youth Service. Its primary objective has been to examine the influencing elements that encourage or impede the activation of social entrepreneurship in the youth sector in Ireland. Also, how through participation in social entrepreneurship activity young people can be linked with further education, training or attachment to the labour market. Using a mixed method data gathering approach by means of a quantitative online national survey and qualitative semi-structured interviews, this research has garnered an understanding of how practitioners and key stakeholders conceptualise the …

Land Use Regulation And Access To Amenities: Exploring Spatial Equity Using Gis, Robert B. Thompson

Theses

No abstract provided.

The Case For Health Literacy Research In Qatar: Identifying Avenues For Progress, Yasar Alani

Theses

Abstract This thesis studies the attitudes of healthcare provider and consumer groups in Qatar towards health literacy via health promotion. Using Q methodology, data from healthcare providers and consumers was analysed to determine relative attitudes towards previous and future health campaign strategies in Qatar. Consumer data was also collected to determine attitudes towards current health promotion campaigns and the perceived effectiveness of campaigns in encouraging behaviour change. The research also investigates the obstacles that prevent healthcare consumers from adopting the healthier lifestyle choices advocated by some of these campaigns. Participants were residents of Qatar.

The concept of health literacy was …

An Investigation Of Nurse Education Service Models In Acute Care Metropolitan Hospitals Across Australia, Carolyn Keane

Theses

The provision of continuing professional development for nurses is necessary to support the delivery of safe patient care. Nurse education departments need to function as effectively and efficiently as possible, producing measurable outcomes to justify their cost in regard to the organisation’s financial bottom line. In reviewing the literature, three recognised models of nurse education services within hospitals were identified. These are described as centralised, decentralised and combination models. All of these models have advantages and disadvantages that can affect service delivery, quality of service and cost.

The purpose of this study was to investigate the different nurse education service …

Introducing Design For Six Sigma’S Dmadv Methodology To The Packaging Industry, Sumeet Deshpande

Theses

The purpose of this thesis was to introduce a standard method for designing efficient and sustainable packages to the packaging industry. This thesis has focused on how a standardized process has helped to design efficient, cost-effective and sustainable packages in the food industry. The standardized process used was the lean six-sigma methodology called DMADV.

The DMADV methodology has been implemented for inventing and innovating major new features of existing products, services or processes.

The main objective of this research was to:

1. Introduce the lean six-sigma DMADV methodology to the packaging industry.

2. Show how a DMADV methodology can be …

The Role Of Economic Zones And Their Potential To Attract Diaspora Investment In Kosovo, Milot Burani

Theses

The Kosovar diaspora presents a large opportunity for the nation to utilize towards the aim of development. Through the years, the massive amount of resources sent to Kosovo from the diaspora, in the form of remittances, has been realized but has not been effectively utilized and channeled for development projects. The growing reliance on these remittances does not represent a sustainable approach for the country’s development as these inflows and could in fact prove to lead to the exact opposite. In order to make better use of Diaspora funds and increase foreign direct investments in the country, the Kosovar government …

The Effects Of Maturational Variation On The Performance Of Young Australian Footballers And Their Selection Into The Australian Football League's Talent Pathway, Ashley Cripps

Theses

Traditional player development pathways share a common goal, to identify and accelerate the development of talented adolescent players for senior competition. Players who gain selection into development programs gain greater access to experienced coaches, training facilities, support staff and competition. However, despite such advantages, research has shown that few players who gain initial selection into development pathways progress into professional senior competition. A major factor which potentially contributes to poor player retention in development pathways is the initial misidentification of talented athletes due to variations in biological maturity.

Earlier maturing individuals have been shown to be at a physical advantage …

Early Life Events And Motor Development: A Longitudinal Study, Tegan Grace

Theses

Longitudinal studies are important to fully understand the processes of neurological development during gestation and how risk factors present during this time impact motor development outcomes, yet few to date have focused on this critical time period.

The purpose of this study was to identify modifiable risk factors influencing motor development during the prenatal period. Of particular interest was finding out whether these risk factors differed between the sexes.

Participants (N=2900) were from the Western Australian Pregnancy Cohort (Raine) Study. The Raine Study began in May 1989 and women were recruited between 16-20 weeks gestation (m = 18 weeks) from …

Towards The Identification Of Metabolite Markers Of Nipple Pain And Inflammation In Human Milk, Erin Fee

Theses

Background: Human milk is considered the best source of nutrition for all newborns as it contains important growth, developmental and immunological factors. The WHO (2003) recommends exclusive breastfeeding for the first six months of age, with complementary breastfeeding up to two years and beyond. However, some women experience complications of the breast that lead to early cessation of breastfeeding, which can adversely affect the well being of the developing infant and her own health.

Nipple pain is the most commonly cited reason for weaning in the first week postpartum. Nipple pain is also linked to mastitis from milk stasis and …

Does Temporarily Altering Visual Perception Of Limb Size Have A Modulatory Effect On Deep-Tissue Pain? A Repeated-Measures Within-Subjects Randomised Study, M Van Selm

Theses

No abstract provided.

Re-Conceptualising Hirschman's Exit, Voice & Loyalty Model For Contemporary Organisational Contexts, Eileen Gleeson

Theses

This conceptual thesis seeks to re-visit the relevance of Albert Hirschman’s (1970) highly enduring Exit, Voice and Loyalty (EVL) model for understanding contemporary workplace dynamics and organisational member responses to instances of organisational decline or slack. In particular, the thesis focuses on the inclusion of organisational silence and its connection to voice and loyalty. Organisational theorists have begun to enquire into the nature of organizational silence, why it forms and what its consequences may be. What the current literature suggests is that although management desires an engaged, productive and loyal workforce, it does not want members to raise their voice …

A Case Study Of Factors Influencing Remote University Nursing Graduates And Their Decision To Work In A Remote Hospital, Sally Clark

Theses

The health of the rural population in Western Australia (WA) is predicated on equity and access to healthcare facilities with nurses being the main component of front line staff. There continues to be a nurse shortage particularly in remote regions of Australia where the poor health status of Australian Indigenous people, and an increasing ageing population are a perennial problem. The Kimberley, the setting for this study, is a remote region in the north of WA. It has a landmass of 423,517 square kilometres with a significantly low-density population compared to the total WA population. Nearly half of the Kimberley …

The Introduction Of Montessori Teaching And Learning Practices In An Early Childhood Classroom In A Remote Indigenous School, Catherine Holmes

Theses

The purpose of this research was to observe and describe the effect of Montessori pedagogy in a remote Aboriginal Early Childhood program to ascertain whether this alternative approach to education provides a more culturally appropriate practice than past methods. The significance of the study lies in the need to "close the gap" (Department of Premier & Cabinet [DPMC], 2016, p.1) between the achievement of Indigenous and non-Indigenous students. The study endeavours to describe the effect of Montessori pedagogy through the response of those most closely associated with Aboriginal education: students, parents, caregivers, community members and educational professionals.

Three dimensions of …

Risk Assessment And The Utility Of Ct Coronary Angiography For Coronary Artery Disease In Hiv Infection, James Nadel

Theses

Background

Human immunodeficiency virus (HIV) infection is now considered a chronic, treatable disease, although treatment is associated with increased rates of coronary artery disease (CAD). Screening of this at-risk population for CAD remains contentious. The aim of this thesis is to provide some guidance into the management of cardiovascular disease in HIV and examine the utility of screening CTCA in this population group.

Methods

We set out to disseminate our generated results via publications. The first paper was a literature review that sought to provide insight into the management of this complex population, in particular focusing on the risk assessment …

Dna Methylation Biomarkers For Esophageal Adenocarcinoma And Precursor Disease, Melissa L. Thomas

Theses

Esophageal adenocarcinoma has one of the poorest outcomes of all solid tumors, attributable, at least in part, to lack of an early stage diagnostic test. Aberrant methylation is an early and frequent event in carcinogenesis providing an opportunity for early cancer detection. The overall aim of this thesis is to identify and validate regions of aberrant methylation as a biomarker for early detection of esophageal adenocarcinoma and the dysplastic stages of its precursor disease, Barrett’s esophagus. By using well-classified patient data and stringent, quality controlled biospecimen selection for training and validation cohorts, I found regions of diseaseassociated aberrant methylation that …

An Implementation Of A High Accuracy Sensor For Distributed Wireless Sensor Network Applications, Jesse Craig Frye

Theses

Biopotentials are typically small electric signals, on the order of a few microvolts to hundreds of millivolts, produced as the result of cellular electrochemical activity in living organisms. Due to high source impedance, investigation of these small electrical signals typically requires use of clinical equipment or professional data acquisition systems that are large, expensive, and utilize AC mains power. Distributed sensor network applications need a low cost, high resolution wireless sensor, suitable for measuring and logging microvolt-level DC accurate signals from high impedance sources. Issues that must be addressed include processing power, power efficiency, auxiliary data storage, and wireless communication …

Performance Of Feature Selection Methods For Machine Learning Based Automatic Malarial Cell Recognition In Wholeslide Images, Vishnu Muralidharan.

Theses

This work is on investigation of automated detection of malaria parasites in wholeslide images of peripheral blood smears. We compared and analyzed several feature-selection methods for optimization of machine learning using support vector machine (SVM). To this end, cell samples were extracted from the wholeslide image and feature extraction was performed on these samples. In order to identify the best features, a host of feature selection methods were tested. For each set of selected features, the SVM was trained and tuned for optimal model selection using cross-validation and grid-search. Subsequently, test samples were classified using the model. Each feature selection …

Ballymaloe Cookery School: A Study Of The Business And Its Local Impact, Keelin Tobin

Theses

The focus of this research is Ballymaloe Cookery School situated in East Cork, Ireland. This study seeks to understand the emergence of the cookery school, how this business has evolved over time and to investigate the impact it has had on the local area. Ballymaloe Cookery School was officially founded by brother and sister, Darina Allen (nee O’Connell) and Rory O’Connell in Shanagarry, Co. Cork in 1983. The findings examine the establishment of the cookery school as a family business and its attributes. Set amongst a rural landscape, close to the sea and surrounded by agricultural land, the school is …

An Investigation Of The Role Of Finance In The Development Of Value Added Products, John O'Sullivan

Theses

Traditionally Ireland focused on commodity based food products. In recent years there has been a shift towards value added food products. There has however been little academic research undertaken investigating the role of finance in developing value added products. This study will examine the importance of the value added food sector in the Irish food industry and will also examine new product development (NPD) processes to highlight the role finance plays in developing value added food products. The researcher used semi-structured interviews of seven industry experts as the research technique.

Value added products have many benefits including higher margin and …

High Borate Glasses For The Controlled Release Of Therapeutic Metal Ions, Kathleen O'Connell

Theses

Within the biomaterial community significant effort has been directed towards engineering materials that induce precise host responses, which are tailored to specific applications. However, this has also seen an increase in the complexity of some biomaterials, which is being increasingly criticised within the literature, as it is attributed to hindering their clinical utility. In this context the release of therapeutic metal ions from glass-based biomaterials have been shown to promote hard tissue repair and regeneration through angiogenesis and osteogenesis processes. Within this thesis project two separate quaternary high borate glass systems were prepared containing the therapeutic metal ions strontium and …

Low-Cost Fabrication Of Nanoelectrodes For Electrochemical Applications, Colm Barrett

Theses

Compared to traditional macroelectrodes, nanoscale electrodes have tremendous potential when employed in electrochemistry due to enhanced sensitivity arising from increased mass transport to the electrode and low background charging currents. Electrochemically- based diagnostic products such as sensors require sensing elements with greatly enhanced performance and nanoelectrodes offer a viable route to attaining this performance improvement.

Firstly, the fabrication of a polymer microneedle array-based sensor is described and employed to demonstrate a mediated approach for the detection of glucose in solution. This was to demonstrate the feasibility of the system for in-vivo sensing. Cyclic voltammetry was used to achieve detection of …

Suspended Sediment And Nutrient Concentrations And Loads In Two Irish Rivers, Sean T. Harrington

Theses

This thesis presents the results of new and original research on suspended sediment (SS) and nutrient concentrations and loads on the Rivers Bandon and Owenabue in the south of Ireland. It addresses the knowledge gap in SS and nutrient concentration data and in particular SS load/yield estimation methods. A comprehensive database of SS and nutrient concentrations has been established. An investigation into the relationship between water discharge and sediment and nutrient transport is presented and new original relationships between turbidity and suspended sediment concentration (SSC) and nutrients are developed. Turbidity-based suspended sediment loads (SSL) are estimated from the continuous turbidity …

Geochemical Investigation Of Anomalous Arsenic Enrichment In The Santiago Peak Volcanics Of Southern California, Elizabeth C. Johnston

Theses

Arsenic (As) is enriched in the Santiago Peak Volcanics (SPV) that crop out at Black Mountain Open Space Park in San Diego, CA. Thus, the Black Mountain SPV present an excellent opportunity to investigate As enrichment in ancient volcanic arc systems as a result of deep earth subduction zone processes. Through targeted field study of this unit, we aim to (1) confirm the volcanic arc provenance of rocks cropping out at Black Mountain, (2) investigate As enrichment in relation to volcanic arc processes, and (3) propose a model for As occurrence in the SPV. Our findings indicate Black Mountain SPV …