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In This Issuereview Articleoriginal Articlescase Report Oct 2022

In This Issuereview Articleoriginal Articlescase Report

Saudi Medical Journal

No abstract provided.


Molecular Characterization Of Helicobacter Pylori Clinical Isolates From Eastern Saudi Arabia, Khaled R. Alkharsah, Reem Y. Aljindan, Aisha M. Alamri, Amer I. Alomar, Abdulaziz A. Al-Quorain Oct 2022

Molecular Characterization Of Helicobacter Pylori Clinical Isolates From Eastern Saudi Arabia, Khaled R. Alkharsah, Reem Y. Aljindan, Aisha M. Alamri, Amer I. Alomar, Abdulaziz A. Al-Quorain

Saudi Medical Journal

Objectives: To describe the frequency of cytotoxin-associated gene A ( CagA ) and vacuolating cytotoxin A ( VacA ) virulence genes and clarithromycin resistance-associated mutations among Helicobacter pylori ( H. pylori ) clinical isolates from Eastern Saudi Arabia. Methods: A cross-sectional study was carried out between July 2020 and June 2021 in a tertiary hospital in AL-Khobar, Saudi Arabia. A total of 34 H. pylori isolates were obtained from gastric biopsies of patients with dyspepsia. The existence of the virulence genes was studied by polymerase chain reaction and the gene fragment of the 23s ribosomal subunit ( 23s rRNA ) …


Prevalence And Predictive Factors For Infertility-Related Stress Among Infertile Couples: A Cross-Sectional Study From Jordan And The Occupied Palestinian Territories, Deema J. Jaber, Haneen A. Basheer, Abla M. Albsoul-Younes, Lina M. Elsalem, Jehan M. Hamadneh, Mohammad K. Dweib, Hanadi T. Ahmedah Oct 2022

Prevalence And Predictive Factors For Infertility-Related Stress Among Infertile Couples: A Cross-Sectional Study From Jordan And The Occupied Palestinian Territories, Deema J. Jaber, Haneen A. Basheer, Abla M. Albsoul-Younes, Lina M. Elsalem, Jehan M. Hamadneh, Mohammad K. Dweib, Hanadi T. Ahmedah

Saudi Medical Journal

Objectives: To assess the level of infertility-related stress, associated socio-economic, and demographic factors among infertile couples living in Jordan and those living under the chronic Israeli-Palestinian conflict in the occupied Palestinian territories. Methods: A cross-sectional study was carried out in a number of fertility and reproductive clinics in Jordan and occupied Palestinian territories over a period of 6 months. Trained clinical pharmacists interviewed the identified couples. Results: A total of 443 participants were interviewed. Three variables were significantly and independently associated with global stress scores. The need of parenthood appears higher in women than men among infertile couples in Jordan …


Investigation Of The Analgesic Efficacy Of Ultrasound-Guided Thoracolumbar Interfacial Plane Block In Vertebral Surgery: A Prospective Randomized Clinical Study, Hakan Tapar, Özgür Demir, Ali Genç, Mehtap G. Balta, Vildan Kölükçü, Tugba Karaman, Serkan Dogru, Serkan Karaman, Mustafa Suren Oct 2022

Investigation Of The Analgesic Efficacy Of Ultrasound-Guided Thoracolumbar Interfacial Plane Block In Vertebral Surgery: A Prospective Randomized Clinical Study, Hakan Tapar, Özgür Demir, Ali Genç, Mehtap G. Balta, Vildan Kölükçü, Tugba Karaman, Serkan Dogru, Serkan Karaman, Mustafa Suren

Saudi Medical Journal

Objectives: To investigate the effect of thoracolumbar interfacial plane block (TLIP) on analgesic consumption and pain score in vertebral surgery. Methods: All patients (64 patients undergoing vertebral surgery) were randomly allocated as Group T (patients with block, n=32) and Group C (patients without block, n=32). After surgery, patient-controlled analgesia using tramadol was administered to all patients. Pain intensity was evaluated with visual analogue scale (VAS; recovery room at 1, 2, 6, 12, and 24 hours postoperative), and as rescue analgesia, morphine was administered to patients with VAS scores of >4. In this study, total tramadol consumption, the number of patients …


Combining Stellate Ganglion Block And Intravenous Regional Anesthesia To Treat Complex Regional Pain Syndrome: A 19-Years’ Experience In A Tertiary Center, Abdelkarim S. Aloweidi, Mahmoud M. Al-Mustafa, Islam M. Massad, Ibraheem Y. Qudaisat, Aws M. Khanfar, Jihad M. Ajlouni, Shaher T. Alhadidi, Ahmad I. El-Share, Mohammad A. Jarbeh, Anas A. Al-Oweidi Oct 2022

Combining Stellate Ganglion Block And Intravenous Regional Anesthesia To Treat Complex Regional Pain Syndrome: A 19-Years’ Experience In A Tertiary Center, Abdelkarim S. Aloweidi, Mahmoud M. Al-Mustafa, Islam M. Massad, Ibraheem Y. Qudaisat, Aws M. Khanfar, Jihad M. Ajlouni, Shaher T. Alhadidi, Ahmad I. El-Share, Mohammad A. Jarbeh, Anas A. Al-Oweidi

Saudi Medical Journal

Objectives: To study reduction in pain score after treatment with intravenous regional anesthesia (IVRA) and Stellate ganglion block (SGB) combination on complex regional pain syndrome (CPRS) patients and to quantify patients’ satisfaction with treatment and occurrence of complications. Methods: This is a record-based retrospective review carried out in 2020, targeting patients treated in the University of Jordan Hospital, Amman, Jordan, over the years 2002-2020. Results: Among 99 patients, a significant drop in pain scores occurred in 88% of the patients’ sample. Gender, age, type of CRPS, and duration of symptoms didn’t affect statistical results. An average of 8.6 sessions needed …


Clinical Efficacy Of Ultrasound Guided Erector Spinae Plane Block In Patients Undergoing Microwave Ablation, Özlem Öz Gergin, Sibel Seçkin Pehlivan, İbrahim Erkan, Adnan Bayram, Recep Aksu, Cihangir Biçer, Karamehmet Yıldız, Güven Kahriman Sep 2022

Clinical Efficacy Of Ultrasound Guided Erector Spinae Plane Block In Patients Undergoing Microwave Ablation, Özlem Öz Gergin, Sibel Seçkin Pehlivan, İbrahim Erkan, Adnan Bayram, Recep Aksu, Cihangir Biçer, Karamehmet Yıldız, Güven Kahriman

Saudi Medical Journal

Objectives: To compare the effect of pre-emptive erector spinae plane block (ESPB) applied before the procedure on opioid consumption during the procedure and analgesic demand and opioid consumption after the procedure. Methods: American Society of Anesthesiologists Physical Status Classification (ASA) I-II, 30 patients, with liver tumor and planned for microwave ablation (MWA) treatment were included in the interventional radiology clinic, Erciyes University, Kayseri, Turkey, Turkey between 2021 and 2022. Patients were randomized either to the ESPB or control group. Ultrasound-guided ESPB block with 20 mL of 0.25% bupivacaine was performed preoperatively in the ESPB group patients, and the patients who …


Venous Thromboembolism In Covid-19: A Meta-Summary Of Cases, Naif Saad Alghasab, Leen A. Altamimi, Mohammed Salem Alharbi, Sulaman S. Almesned, Aditya K. Khetan Sep 2022

Venous Thromboembolism In Covid-19: A Meta-Summary Of Cases, Naif Saad Alghasab, Leen A. Altamimi, Mohammed Salem Alharbi, Sulaman S. Almesned, Aditya K. Khetan

Saudi Medical Journal

Objectives: To summarize cases of venous thromboembolism (VTE), including pulmonary embolism (PE) and deep vein thrombosis (DVT) among coronavirus disease (COVID-19) patients and discuss their symptoms, diagnostic method, clinical features, and prognosis. Methods: All major databases were searched for relevant studies published between December 1, 2019 and May 5, 2021. Results: A total of 233 articles were identified, 22 describing 48 patients were included. A total of 79.1% had PE and 20.9% had DVT. Most patients were men, with a mean age of 56 years. Comorbidities were present in 70.8%, and 85.4% had at least one risk factor of VTE. …


Epicardial Adipose Tissue Thickness And Growth Differentiation Factor 15 In Axial Spondyloarthritis: A Cross-Sectional Study, Mehmet Okçu, Fatmanur A. Koçak, Senem Şaş, Kenan Güçlü Sep 2022

Epicardial Adipose Tissue Thickness And Growth Differentiation Factor 15 In Axial Spondyloarthritis: A Cross-Sectional Study, Mehmet Okçu, Fatmanur A. Koçak, Senem Şaş, Kenan Güçlü

Saudi Medical Journal

Objectives: To investigate growth differentiation factor-15 (GDF-15) levels and the thickness of epicardial adipose tissue (EAT) in patients with axial spondyloarthritis (axSpA) and to evaluate their relationship with functional status, disease activity, disease duration, and the type of medical treatment received by the patients. Methods: This cross-sectional study was carried out at Kırşehir Ahievran University School of Medicine between February and June 2020. Twenty-nine healthy controls and 44 patients with axSpA were included in the study. Gender, age, erythrocyte sedimentation rate, GDF-15, body mass index, complete blood count, ejection fraction, the EAT thickness, and C-reactive protein of all participants were …


In This Issuesystematic Revieworiginal Articlescase Report Sep 2022

In This Issuesystematic Revieworiginal Articlescase Report

Saudi Medical Journal

No abstract provided.


Prevalence Of Carbapenemase Genes Among Multidrug-Resistant Pseudomonas Aeruginosa Isolates From Tertiary Care Centers In Southern Thailand, Phanvasri Saengsuwan, Narongdet Kositpantawong, Soontara Kawila, Wichien Patugkaro, Chonticha Romyasamit Sep 2022

Prevalence Of Carbapenemase Genes Among Multidrug-Resistant Pseudomonas Aeruginosa Isolates From Tertiary Care Centers In Southern Thailand, Phanvasri Saengsuwan, Narongdet Kositpantawong, Soontara Kawila, Wichien Patugkaro, Chonticha Romyasamit

Saudi Medical Journal

Objectives: To assess the prevalence of carbapenemase genes among multidrug-resistant Pseudomonas aeruginosa ( P. aeruginosa ) isolates from tertiary care centers in Southern Thailand. Methods: The prevalence of carbapenemase genes in P. aeruginosa isolates collected from patients hospitalized between 2015-2017 in 2 tertiary care hospitals in Songkhla Province, Southern Thailand, was investigated. Standard laboratory procedures were followed and disk diffusion test was used for bacterial identification and susceptibility evaluations. Carbapenemase genes were detected using multiplex polymerase chain reaction (PCR) and genotyping by pulsed field gel electrophoresis. Results: Among the 289 P. aeruginosa isolates, 55% was from sputum, 19.4% was from …


Comment On: Fracture Risk Assessment In Patients With Type 2 Diabetes Mellitus, Ali S. Jawad Sep 2022

Comment On: Fracture Risk Assessment In Patients With Type 2 Diabetes Mellitus, Ali S. Jawad

Saudi Medical Journal

No abstract provided.


Who Makes New Recommendations For Ebola Treatments, Calls For Improved Access Sep 2022

Who Makes New Recommendations For Ebola Treatments, Calls For Improved Access

Saudi Medical Journal

No abstract provided.


The Prevalence Of Serious Bacterial Infections In Infants 90 Days And Younger With Viral Respiratory Tract Infections, Abdullah I. Almojali, Musab S. Alshareef, Othman F. Aljadoa, Fahad F. Alotaibi, Emad M. Masuadi, Tahir K. Hameed Sep 2022

The Prevalence Of Serious Bacterial Infections In Infants 90 Days And Younger With Viral Respiratory Tract Infections, Abdullah I. Almojali, Musab S. Alshareef, Othman F. Aljadoa, Fahad F. Alotaibi, Emad M. Masuadi, Tahir K. Hameed

Saudi Medical Journal

Objectives: To determine the prevalence and risk factors of serious bacterial infections (SBIs) in infants 90 days and younger with a confirmed respiratory tract infection (RTI). Methods: A retrospective cross-sectional study was carried out of infants 90 days and younger who were admitted to King Abdullah Specialized Children’s Hospital, Riyadh, Saudi Arabia, from January 2019 to December 2020, with polymerase chain reaction (PCR)-proven RTI. Cultures from the urine, blood, and cerebrospinal fluid were reviewed with the patients’ demographic information and clinical presentation. Results: Of 322 patients with a viral RTI, 21 (6.5%) had a concurrent urinary tract infection (UTI), and …


Clinical Characteristics And Outcomes Among Patients With Covid-19: A Single-Center Retrospective Observational Study From Marj, Libya, Aimen M. Khalifa, Fatimah A. Nouh, Farag A. Elshaari Sep 2022

Clinical Characteristics And Outcomes Among Patients With Covid-19: A Single-Center Retrospective Observational Study From Marj, Libya, Aimen M. Khalifa, Fatimah A. Nouh, Farag A. Elshaari

Saudi Medical Journal

Objectives: To describe the clinical characteristics and the contributing factors potentially associated with the poorer outcome in Libyan COVID-19 ICU patients. Methods: The present work is a retrospective, single-center study, which included 94 COVID-19 patients admitted to the Isolation Department at Marj Hospital from August 21st, 2020 till April 30th, 2021. The patients’ data, including their medical history, clinical manifestations, radiological imaging, and laboratory findings, were obtained from the hospital records. Results: A higher proportion of the admitted patients were males. The patients’ mean age was 68.29 ± 13.64. The patients came with varying symptoms, but most commonly they were …


Pediatric Ovarian Sliding Inguinal Hernia, Is Surgical Repair Urgent?, Mutaz M. Gieballa, Suliaman M. Alaqeel, Mohammad A. Aldaffaa Sep 2022

Pediatric Ovarian Sliding Inguinal Hernia, Is Surgical Repair Urgent?, Mutaz M. Gieballa, Suliaman M. Alaqeel, Mohammad A. Aldaffaa

Saudi Medical Journal

Objectives: To find if repairing sliding inguinal hernias containing the ovary should be carried out urgently or not. Methods: A retrospective chart review carried out at King Abdulaziz Medical City, Riyadh, Saudi Arabia from 2015-2022. All cases with an ovarian inguinal hernia in females aged 0-14 years were reviewed after obtaining approval from the Institutional Review Board. Results: Female children with inguinal hernia patients were 191. A total of 28 cases were sliding inguinal hernias involving the ovary. All were repaired electively except for 4 cases that had an initial presentation of an incarcerated ovary at age less than 90 …


Are Women Diagnosed With Early Pregnancy Loss At Risk For Anxiety, Depression, And Perinatal Grief?, Levent Ozgen, Gulten Ozgen, Deniz Simsek, Burcu Dıncgez, Feyza Bayram, Ayten N. Mıdıkhan Sep 2022

Are Women Diagnosed With Early Pregnancy Loss At Risk For Anxiety, Depression, And Perinatal Grief?, Levent Ozgen, Gulten Ozgen, Deniz Simsek, Burcu Dıncgez, Feyza Bayram, Ayten N. Mıdıkhan

Saudi Medical Journal

Objectives: To examine the effects of early pregnancy loss on emotions such as depression, grief, or a sense of hopelessness, while investigating different types of diagnoses, hospital stays, and treatments. Methods: A prospective cohort epidemiological study was carried out in Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey, between January and September 2019. The study included women diagnosed with early pregnancy loss classified into 3 groups: missed abortus, anembryonic pregnancy, and spontaneous abortion. The patients were screened via the Spielberger state-anxiety inventory (STAI-1) before initiating treatment. The Edinburgh postpartum depression scale (EPDS) and Perinatal Grief Scale (PGS) were also …


Double Malignancy And A Mycobacterial Infection In A Rheumatoid Arthritis Patient, Huda Alfaris, Sarah A. Alkathiri, Doha Babelli, Fahdah Alokaily Sep 2022

Double Malignancy And A Mycobacterial Infection In A Rheumatoid Arthritis Patient, Huda Alfaris, Sarah A. Alkathiri, Doha Babelli, Fahdah Alokaily

Saudi Medical Journal

Rheumatoid arthritis is a common autoimmune disease. Malignancy is a serious complication of rheumatoid arthritis and its treatment. In this article, we discuss a 61-year-old woman who is a known case of Rheumatoid arthritis and secondary Sjögren’s syndrome treated with disease-modifying anti-rheumatoid drugs and multiple lines of biological therapies. She was found to have recto-sigmoid cancer, disseminated tuberculosis infection, and acute lymphoid leukemia at different intervals of treatment. Therefore, it is advisable to initiate appropriate screening programs that target high-risk people for malignancy.


Does Fraud Victimization Affect A Person’S Long-Term Blood Pressure? Sep 2022

Does Fraud Victimization Affect A Person’S Long-Term Blood Pressure?

Saudi Medical Journal

No abstract provided.


Monkeypox: Experts Give Virus Variants New Names Sep 2022

Monkeypox: Experts Give Virus Variants New Names

Saudi Medical Journal

No abstract provided.


Seroprevalence Of Community-Acquired Atypical Bacterial Pneumonia Among Adult Covid-19 Patients From A Single Center In Al Madinah Al Munawarah, Saudi Arabia: A Retrospective Cohort Study, Sari T. Alhoufie, Nadir A. Ibrahim, Naif H. Alsharif, Khalid O. Alfarouk, Hatim M. Makhdoom, Khaled R. Aljabri, Sayed H. Saeed, Adnan A. Khoumaeys, Yahya A. Almutawif, Mustafa A. Najim, Hamza M. Ali, Alanoud A. Aljifri, Ali M. Kheyami, Areej A. Alhazmi Sep 2022

Seroprevalence Of Community-Acquired Atypical Bacterial Pneumonia Among Adult Covid-19 Patients From A Single Center In Al Madinah Al Munawarah, Saudi Arabia: A Retrospective Cohort Study, Sari T. Alhoufie, Nadir A. Ibrahim, Naif H. Alsharif, Khalid O. Alfarouk, Hatim M. Makhdoom, Khaled R. Aljabri, Sayed H. Saeed, Adnan A. Khoumaeys, Yahya A. Almutawif, Mustafa A. Najim, Hamza M. Ali, Alanoud A. Aljifri, Ali M. Kheyami, Areej A. Alhazmi

Saudi Medical Journal

Objectives: To investigate the seroprevalence of the community-acquired bacterial that causes atypical pneumonia among confirmed severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) patients. Methods: In this cohort study, we retrospectively investigated the seroprevalence of Chlamydia pneumoniae , Mycoplasma pneumoniae , and Legionella pneumophila among randomly selected 189 confirmed COVID-19 patients at their time of hospital presentation via commercial immunoglobulin M (IgM) antibodies against these bacteria. We also carried out quantitative measurements of procalcitonin in patients’ serum. Results: The seropositivity for L. pneumophila was 12.6%, with significant distribution among patientsolder than 50 years (χ2 test, p =0.009), while those of M. …


Cardiac Myxoma Presenting With Multisystem Involvement, Ghofran A. Ageely, Salhah S. Alsulami, Ahad A. Alkenani, Ebtihal Ems. Albeshri Sep 2022

Cardiac Myxoma Presenting With Multisystem Involvement, Ghofran A. Ageely, Salhah S. Alsulami, Ahad A. Alkenani, Ebtihal Ems. Albeshri

Saudi Medical Journal

A cardiac myxoma is a rare tumor that could be incidental or present with common symptoms due to embolization. A minority of cases are attributed to carney complex, a rare inherited disease. A 73-year-old Asian male presented with acute left-side weakness, slurred speech, gait imbalance, and subacute constitutional symptoms. Left atrial myxoma was discovered by computed tomography and confirmed by echocardiography. Brain imaging revealed pituitary macroadenoma with subarachnoid and intraventricular hemorrages. The hormonal profile confirmed pituitary apoplexy, for which hormone replacement was initiated. Workup also revealed multiple endocrine tumors and excluded infection and malignancy. Myxoma resection could not be carried …


Profile And Primary Treatment Outcomes In Membranous Nephropathy, M.K. Hemanth Kumar, Jashan Sandhu, Jasvinder S. Sandhu Sep 2022

Profile And Primary Treatment Outcomes In Membranous Nephropathy, M.K. Hemanth Kumar, Jashan Sandhu, Jasvinder S. Sandhu

Saudi Medical Journal

Objectives: To assess the clinical profile and primary treatment response and outcomes in idiopathic membranous nephropathy (IMN) patients. Methods: This study was carried out between December 2013 and January 2019 in a tertiary care hospital in North India on 2 years retrospective and 3 years prospective renal biopsy proven patients with IMN presenting with nephrotic syndrome. Basic baseline investigations carried out were urinary proteins, serum albumin, serum creatinine, other special tests wherever necessary or possible (including phospholipase A2 receptor antibodies), and different treatment regimens were offered for treatment. The patients were followed up for a minimum period of 6 months …


Radiation Metrics For Vascular And Interventional Radiology Procedures In A Tertiary Care Institution: A Retrospective Cohort Study Over 5-Years, Mohammad Arabi, Ali S. Rajeh, Nasser Alhendi, Khalid T. Alotaibi, Talal A. Yahyan, Khalid Alyousef, Husam Ardah Sep 2022

Radiation Metrics For Vascular And Interventional Radiology Procedures In A Tertiary Care Institution: A Retrospective Cohort Study Over 5-Years, Mohammad Arabi, Ali S. Rajeh, Nasser Alhendi, Khalid T. Alotaibi, Talal A. Yahyan, Khalid Alyousef, Husam Ardah

Saudi Medical Journal

Objectives: To evaluate the radiation metrics from frequently carried out vascular and interventional radiology (VIR) procedures at a tertiary care institution and compare them to international diagnostic reference levels (DRLs). Methods: A retrospective study of the radiation metrics of VIR-procedures carried out from January 2015 to December 2019. The collected data included age, gender, height and weight, reference point air kerma (mGy), dose area product (DAP; Gy.cm2), and fluoroscopy time (min.) The body mass index (BMI) and peak skin dose were calculated. The study cohort included 8942 adult patients (54.4% male, 45.6% female) with a mean age of 56.96 years …


Why Do Men Face A Higher Risk Of Most Types Of Cancer Than Women? Sep 2022

Why Do Men Face A Higher Risk Of Most Types Of Cancer Than Women?

Saudi Medical Journal

No abstract provided.


Urgent Call For Better Use Of Existing Vaccines And Development Of New Vaccines To Tackle Amr Aug 2022

Urgent Call For Better Use Of Existing Vaccines And Development Of New Vaccines To Tackle Amr

Saudi Medical Journal

No abstract provided.


Impact Of Covid-19 Pandemic Quarantine On Dietary Behaviors And Lifestyle Of Saudi Adults In Jeddah, Kingdom Of Saudi Arabia, Eilaf H. Braiji, Eman A. Abduljawad, Amani A. Alrasheedi Aug 2022

Impact Of Covid-19 Pandemic Quarantine On Dietary Behaviors And Lifestyle Of Saudi Adults In Jeddah, Kingdom Of Saudi Arabia, Eilaf H. Braiji, Eman A. Abduljawad, Amani A. Alrasheedi

Saudi Medical Journal

Objectives: To investigate how the coronavirus disease 2019 (COVID-19) pandemic quarantine affected Saudi adults’ dietary behaviors and lifestyles in Jeddah, Saudi Arabia. Methods: A retrospective cross-sectional study using an electronic questionnaire was adopted. A total of 476 Saudis residing in Jeddah were involved with the investigation. The study was carried out from March to May 2021. The questionnaire addressed dietary behaviors (types of foods consumed) and lifestyle behaviors (food shopping, physical activity, and sleep quality). Results: The study participants aged 18-65 years, 70.2% were females, mainly non-infected with coronavirus previously (88.7%). Fast food consumption as (pizza and burgers) decreased significantly …


Prevalence Of Obesity In Treated And Untreated Patients With Attention Deficit Hyperactivity Disorder: A Meta-Analysis, Fatimah Alahmari, Mohy Uddin Aug 2022

Prevalence Of Obesity In Treated And Untreated Patients With Attention Deficit Hyperactivity Disorder: A Meta-Analysis, Fatimah Alahmari, Mohy Uddin

Saudi Medical Journal

Objectives: To discuss and summarize the scholarly published literature on the difference in obesity rate in treated and untreated attention deficit hyperactivity disorder (ADHD) patients to evaluate the influence of ADHD medication on weight status in these individuals. Methods: PubMed, Cochrane Library, and Google Scholar databases were searched for eligible articles from January to December 2020 using the following medical subject headings (MeSH) terms: “attention deficit hyperactivity disorder and other hyperactivity disorders”, “obesity and overweight”, “obesity treatment”. Results: A total of 19,449 study participants included in selected 8 studies were assessed with respect to the prevalence of obesity in medicated …


Antidiabetic And Antioxidant Potential Of Gardenia Latifolia In Type-2 Diabetic Rats Fed With High-Fat Diet Plus Low-Dose Streptozotocin, Ali M. Alshabi, Ibrahim A. Shaikh Aug 2022

Antidiabetic And Antioxidant Potential Of Gardenia Latifolia In Type-2 Diabetic Rats Fed With High-Fat Diet Plus Low-Dose Streptozotocin, Ali M. Alshabi, Ibrahim A. Shaikh

Saudi Medical Journal

Objectives: To test the antidiabetic potential of Gardenia latifolia extract (GLE) in rats with type 2 diabetes mellitus (T2DM) induced by a high-fat diet (HFD) + streptozotocin (STZ). Methods: The study was carried out in June 2021. Gardenia latifolia powdered leaves were subjected to Soxhlet extraction using ethanol. Male rats were administered a low dose-40 mg/kg STZ by intraperitoneal route following 2 weeks of HFD to induce type-2 diabetic rats (T2DR). Rats were randomized into 5 groups (n=6). Group 1 (normal control; 10 ml/kg normal saline); Group 2 (diabetic control: DC); Group 3 (standard; DR + metformin, 100 mg/kg per …


Effects Of Different Fresh Gas Flows On Carboxyhemoglobin Levels: Non-Invasive Carbon Monoxide Monitoring: A Randomized Clinical Trial, Bengü G. Köksal, Gamze Küçükosman, Pişkin Özcan, Çağdaş Baytar, Keziban Bollucuoğlu, Rahşan D. Okyay, Hilal Ayoğlu Aug 2022

Effects Of Different Fresh Gas Flows On Carboxyhemoglobin Levels: Non-Invasive Carbon Monoxide Monitoring: A Randomized Clinical Trial, Bengü G. Köksal, Gamze Küçükosman, Pişkin Özcan, Çağdaş Baytar, Keziban Bollucuoğlu, Rahşan D. Okyay, Hilal Ayoğlu

Saudi Medical Journal

Objectives: To observe the effect of different fresh gas flows (FGF) on carboxyhemoglobin (COHb) levels non-invasively and continuously and to determine the contribution of the smoking status to intraoperative carbon monoxide (CO) accumulation and respiratory complications. Methods: A total of 64 patients were included in the study. Carboxyhemoglobin level was monitored non-invasively from the fingertip. Patients were divided into 2 according to the FGF as low-flow anesthesia (LFA; Group L) and high flow anesthesia (Group H). Each group was divided again into 2 groups as smokers and non-smokers. Carboxyhemoglobin and and the respiratory complications that occurred in the post-anesthesia care …


Survival, Mortality, And Related Comorbidities Among Covid-19 Patients In Saudi Arabia: A Hospital-Based Retrospective Cohort Study, Mohammad A. Al-Ghamdi, Rajaa M. Al-Raddadi, Iman K. Ramadan, Ahmad A. Mirza, Hanan A. Alsaab, Hani F. Alobaidi Aug 2022

Survival, Mortality, And Related Comorbidities Among Covid-19 Patients In Saudi Arabia: A Hospital-Based Retrospective Cohort Study, Mohammad A. Al-Ghamdi, Rajaa M. Al-Raddadi, Iman K. Ramadan, Ahmad A. Mirza, Hanan A. Alsaab, Hani F. Alobaidi

Saudi Medical Journal

Objectives: To assess the survival of COVID-19 patients in Saudi Arabia and to investigate possible mortality predictors. Methods: This is a retrospective cohort study involving 248 patients with severe acute respiratory syndrome coronavirus-2 who were admitted to the primary COVID-19 referral hospital in Jeddah between March and June of 2020. Socio-demographic characteristics, comorbidities, laboratory investigations, management protocols, complications, treatment options, and mortality data were extracted from electronic medical records. The time analysis began at the first signs of illness thorough discharge or death. Results: Our study showed that in-hospital complications including heart failure followed by acute renal failure had the …