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Impact Of Treatment On The Health-Related Quality Of Life Of Children With Cancer In Saudi Arabia, Fayzah Hussain Alhussain, Amany Anwar Saeed Alabdullah
Impact Of Treatment On The Health-Related Quality Of Life Of Children With Cancer In Saudi Arabia, Fayzah Hussain Alhussain, Amany Anwar Saeed Alabdullah
Saudi Medical Journal
Objective: The impact of cancer on health-related quality of life (HRQOL) is considerable, particularly for children undergoing oncological treatment. While research has addressed HRQOL in childhood cancer survivors, less attention has been given to those actively undergoing treatment, including in Saudi Arabia. This systematic review aimed to address this gap by quantitatively evaluating studies reporting on the HRQOL of children in Saudi Arabia during their active cancer treatment phase. We also compare these findings with studies from around the world, emphasising demographic, medical and parental predictors of HRQOL. Methods: A comprehensive search of relevant databases (MEDLINE, CENTRAL, Embase, PsycINFO and …
Erratum To ``Childhood Obesity: Global Burden, Multifactorial Etiologies, Biological Mechanisms, And Emerging Interventions For Prevention And Management'' [Saudi Medical Journal 2026; 47(2):183–194], Fahad H. Baali
Saudi Medical Journal
In the manuscript entitled: ``Childhood Obesity: Global Burden, Multifactorial Etiologies, Biological Mechanisms, and Emerging Interventions for Prevention and Management'' Published in Saudi Med J 2026; Vol. 47(2): 183–194. doi: 10.15537/1658-3175.1001
The tables included in the published version were incorrect due to a production error.
Erratum To ``The Association Between Inflammatory Bowel Disease And Ischemic Heart Disease: A Retrospective Cohort Study'' [Saudi Medical Journal 2025 Oct; 46(10):1174–1181], Mahmoud H. Mosli, Dima M. Alsulami, Yara K. Alghamdi, Abdullah S. Badahdah, Asmaa H. Alhibshi, Thamer M. Alamri, Maan S. Alkhattabi, Khames T. Alzahrani, Hadeel A. Alsufyani, Omar I. Saadah
Erratum To ``The Association Between Inflammatory Bowel Disease And Ischemic Heart Disease: A Retrospective Cohort Study'' [Saudi Medical Journal 2025 Oct; 46(10):1174–1181], Mahmoud H. Mosli, Dima M. Alsulami, Yara K. Alghamdi, Abdullah S. Badahdah, Asmaa H. Alhibshi, Thamer M. Alamri, Maan S. Alkhattabi, Khames T. Alzahrani, Hadeel A. Alsufyani, Omar I. Saadah
Saudi Medical Journal
In the manuscript entitled ``The Association between Inflammatory Bowel Disease and Ischemic Heart Disease: A Retrospective Cohort Study,'' published in Saudi Med J 2025 Oct;46(10):1174–1181. doi: 10.15537/smj.2025.46.10.20250181, the affiliation of Dr. Maan Alkhattabi was omitted from the final published version.
The correct affiliation for Dr. Maan Alkhattabi is as follows:
Department of Medicine, Faculty of Medicine, King Abdulaziz University–Rabigh, Jeddah, Kingdom of Saudi Arabia.
Erratum To ``Unmasking Iron Deficiency And Iron Deficiency Anemia In Saudi Arabia'' [Saudi Medical Journal 2025; 46(9):1000–1007], Osman O. Radhwi, Omar M. Raslan, Eman M. Mansory
Erratum To ``Unmasking Iron Deficiency And Iron Deficiency Anemia In Saudi Arabia'' [Saudi Medical Journal 2025; 46(9):1000–1007], Osman O. Radhwi, Omar M. Raslan, Eman M. Mansory
Saudi Medical Journal
In the manuscript entitled ``Unmasking Iron Deficiency and Iron Deficiency Anemia in Saudi Arabia,'' published in Saudi Med J 2025; Vol. 46(9):1000–1007. doi: 10.15537/smj.2025.46.9.20240970.
The correct affiliation should read as follows: Department of Basic Science, College of Medicine, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
Advancing Rheumatology In The Middle East: Mrc 2025 Abstracts, Martin Lee, Ahmed Zayat, Beena Hameed, Elsadeg Sharif, Fahda Al Okaily, Fehaid Alanazi, Francis Kynaston-Pearson, Khalid A. Alnaqbi, Mahmood Hachim, Mayam Al Nesf, Mira Mirashli, Mohammed Tariq, Ravi Gutta, Reem Abdwani, Saadeya Naji, Shamma Lootah, Tareq Al Araimi, Waleed Hafiz, Suad Hannawi
Advancing Rheumatology In The Middle East: Mrc 2025 Abstracts, Martin Lee, Ahmed Zayat, Beena Hameed, Elsadeg Sharif, Fahda Al Okaily, Fehaid Alanazi, Francis Kynaston-Pearson, Khalid A. Alnaqbi, Mahmood Hachim, Mayam Al Nesf, Mira Mirashli, Mohammed Tariq, Ravi Gutta, Reem Abdwani, Saadeya Naji, Shamma Lootah, Tareq Al Araimi, Waleed Hafiz, Suad Hannawi
Saudi Medical Journal
No abstract provided.
Middle East Bifurcation Club Consensus Document On Percutaneous Revascularization Of Bifurcation Lesions In Association With The National Heart Center – Saudi Health Council, Khaled Al-Shaibi, Mirvat Alasnag, Haitham Amin, Ali Nazmi Calik, Ali Almasood, Abdullah Alenezi, Nouf Alanazi, Abdulrahman Almoghairi, Hadi Abu-Hantash, Khaled Almerri
Middle East Bifurcation Club Consensus Document On Percutaneous Revascularization Of Bifurcation Lesions In Association With The National Heart Center – Saudi Health Council, Khaled Al-Shaibi, Mirvat Alasnag, Haitham Amin, Ali Nazmi Calik, Ali Almasood, Abdullah Alenezi, Nouf Alanazi, Abdulrahman Almoghairi, Hadi Abu-Hantash, Khaled Almerri
Saudi Medical Journal
Bifurcation lesions are among the most challenging in percutaneous coronary intervention (PCI), with outcomes affected by anatomy, side-branch disease, and procedural variability. Existing European definitions and strategies require adaptation for Middle Eastern populations, where diabetes, obesity, and hypertension are highly prevalent and present earlier. The Middle East Bifurcation Club (MEBC), with the National Heart Center, used the Nominal Group Technique to standardize bifurcation PCI terminology, techniques, and treatment pathways tailored to regional demographics. The consensus provides evidence-based recommendations on imaging, provisional and 2-stent strategies, POT, and left main versus non-left main bifurcations, alongside practical algorithms and heart team guidance, highlighting …
Rethinking Health-Care Efficiency: A Call For A Multi-Dimensional Framework For Assessing Healthcare System Efficiency, Yasser K. Alotaibi, Ali N. Alharbi
Rethinking Health-Care Efficiency: A Call For A Multi-Dimensional Framework For Assessing Healthcare System Efficiency, Yasser K. Alotaibi, Ali N. Alharbi
Saudi Medical Journal
No abstract provided.
Prevalence Of Brca1 And Brca2 Germline Mutations In Western Saudi Patients With Epithelial Tubo-Ovarian Carcinoma, Wala Mehros, Faisal Aldaheri, Anas Alqarni, Saif Aljehani, Abdulrahman Alnamlah, Alaa Althubaiti, Safaa Huneef, Hatim Jifree
Prevalence Of Brca1 And Brca2 Germline Mutations In Western Saudi Patients With Epithelial Tubo-Ovarian Carcinoma, Wala Mehros, Faisal Aldaheri, Anas Alqarni, Saif Aljehani, Abdulrahman Alnamlah, Alaa Althubaiti, Safaa Huneef, Hatim Jifree
Saudi Medical Journal
Objective: Ovarian cancer represents the most lethal gynecologic malignancy, the epithelial type (EOC) being the most common. BRCA gene mutations are associated with ovarian cancer, younger age at presentation, strong family history of EOC, and multiple malignancies in a single patient. This study calculated the rate of BRCA-positive EOC and compared BRCA-mutated vs non-mutated EOC cases. Methods: This retrospective cohort study, conducted at Princess Noura Oncology Center between May 2016 and December 2023, explored outcomes in BRCA-positive EOC patients. The inclusion criteria covered all EOC cases. A total of 70 patients were selected. Results: Of the 70 …
The Nephroprotective Effects Of Dulaglutide In Patients With Type 2 Diabetes And Chronic Kidney Disease: A Multicenter Saudi Arabian Study, Maha H. Jamal, Hassan A. Alzahrani, Duaa M. Bakhshwin, Ranya A. Ghamri, Fatmah S. Binzomah, Wisam H. Jamal, Moaz W. Abulfaraj
The Nephroprotective Effects Of Dulaglutide In Patients With Type 2 Diabetes And Chronic Kidney Disease: A Multicenter Saudi Arabian Study, Maha H. Jamal, Hassan A. Alzahrani, Duaa M. Bakhshwin, Ranya A. Ghamri, Fatmah S. Binzomah, Wisam H. Jamal, Moaz W. Abulfaraj
Saudi Medical Journal
Objective: This study aimed to evaluate the effectiveness and safety of dulaglutide in individuals with chronic kidney disease (CKD) and type 2 diabetes mellitus (T2DM). Methods: This retrospective cohort study included 212 patients with CKD (stages 1–4) and T2DM treated with once-weekly dulaglutide (1.5 mg) for either 12 or 24 months at three tertiary care centers in Saudi Arabia from January 2021 to December 2023. Safety was assessed based on the presence of adverse events. Efficacy was measured using the changes in estimated glomerular filtration rate (eGFR), glycated hemoglobin (HbA1c), and body mass index (BMI). Changes in efficacy outcomes were …
Combined Predictive Value Of Serum Ngal, Cysc, Urinary Nag, And Egfr For Sepsis-Associated Acute Kidney Injury In Patients In Icu, Yu Han, Wenna Ning, Jian Lu, Jinwei Zhu, Zhiliang Qin, Xiao Wang
Combined Predictive Value Of Serum Ngal, Cysc, Urinary Nag, And Egfr For Sepsis-Associated Acute Kidney Injury In Patients In Icu, Yu Han, Wenna Ning, Jian Lu, Jinwei Zhu, Zhiliang Qin, Xiao Wang
Saudi Medical Journal
Objective: To evaluate critically ill patients who had sepsis and how various kidney-related measurements, including eGFR, NGAL, CysC, and the urinary enzyme NAG, predict the onset of sepsis-induced renal damage. Methods: The 135 individuals who were admitted to our sepsis intensive care within 2 years to the end of early 2024 were recruited on a prospective basis and were enrolled based on the predefined criteria. Upon admission, they were dichotomized into 2 groups of participants who developed septic-associated kidney injury (82) and without (53). A comparison of baseline laboratory analyses and blood and urine baseline examinations in the groups was …
Comparison Of Clinical Outcome Of Mushroom Poisonings With And Without Specific Treatment: A 5-Year Retrospective Analysis, Kamil Deveci, Necmi Baykan, Baycan Kus, Fatma Ünlü, Ömer Salt, Serhat Koyuncu
Comparison Of Clinical Outcome Of Mushroom Poisonings With And Without Specific Treatment: A 5-Year Retrospective Analysis, Kamil Deveci, Necmi Baykan, Baycan Kus, Fatma Ünlü, Ömer Salt, Serhat Koyuncu
Saudi Medical Journal
Objectives: To determine the demographic and clinical characteristics, potential specific antidote treatments, clinical outcomes, and organ failure (morbidity) rates of patients with mushroom poisoning admitted to our center. Methods: We included 425 patients admitted to the emergency department of Kayseri City Hospital complaining of mushroom poisoning, between May 2018 and December 2023, who met the study criteria. Results: The median age of the 425 patients admitted was 51 years (34–63); 49.5% were female (n = 211), and 75% (n = 319) were admitted by ambulance. According to the Poisoning Severity Score, 70.3% (n = 299) of cases were mild, 21.9% …
Ethnic Background As A Determinant Of Thyroid Cancer Risk: A Decade-Long National Cohort Study Reveals Divergent Epidemics In Saudi Arabia, Nizar A. Khamjan
Ethnic Background As A Determinant Of Thyroid Cancer Risk: A Decade-Long National Cohort Study Reveals Divergent Epidemics In Saudi Arabia, Nizar A. Khamjan
Saudi Medical Journal
Objectives: To analyze and compare temporal trends, demographic characteristics, and stage at diagnosis for thyroid cancer (TC) between Saudi and non-Saudi populations in order to identify potential population-specific etiological drivers. Methods: We conducted a national retrospective cohort study of TC cases in Saudi Arabia from 2013–2022. To assess population-level trends, we computed age-standardized incidence rates (ASIRs) and multivariable Poisson regression alongside piecewise regression models for comparative analysis. Results: Among 14,159 total cases, TC incidence increased disproportionately in Saudi nationals, rising from 884 to 1,677 (90%), significantly outpacing the 184 to 275 (49%) increase observed in non-Saudis. The incidence rate ratio …
Comparison Of The Predictive Value Of Crp/Albumin, Crp/Prealbumin, And The Clinical Frailty Scale For Mortality In Geriatric Intensive Care Patients, Natali T. Aksoy, Bülent B. Güven, Sümeyya M. Soyalan, Dilek Metin Yamaç, Tuna Ertürk, Süheyla Abitağaoğlu
Comparison Of The Predictive Value Of Crp/Albumin, Crp/Prealbumin, And The Clinical Frailty Scale For Mortality In Geriatric Intensive Care Patients, Natali T. Aksoy, Bülent B. Güven, Sümeyya M. Soyalan, Dilek Metin Yamaç, Tuna Ertürk, Süheyla Abitağaoğlu
Saudi Medical Journal
Objectives: To evaluate the relationship between C-reactive protein (CRP)/prealbumin and CRP/albumin ratios, Clinical Frailty Scale (CFS) scores, and short-term (first 3 days) and long-term (28 days) mortality in geriatric patients hospitalized in the intensive care unit. Methods: After obtaining ethical approval and informed consent, 213 patients aged 65 years and older were included. Patients discharged within 24 hours, those discharged and readmitted during the study period, those receiving routine albumin replacement, and patients with cirrhosis or undergoing chronic dialysis were excluded. Demographic characteristics, admission diagnoses, chronic comorbidities, frailty scores at admission, and laboratory values, including albumin, prealbumin, and CRP …
Tumor-Associated Neutrophils In Advanced Non-Small Cell Lung Cancer Patients Predicted By Clinicopathologic Characteristics And Peripheral Blood Markers, Weiwei Hong, Xie Xiong, Chen Fang, Chuanhong Luo, Xiaoying Qian, Xinyuan Yao, Xin Ye, Biao Yu, Bingbiao Zhou, Dengying Chen, Chengsi Shu, Yong Wang, Yong Li
Tumor-Associated Neutrophils In Advanced Non-Small Cell Lung Cancer Patients Predicted By Clinicopathologic Characteristics And Peripheral Blood Markers, Weiwei Hong, Xie Xiong, Chen Fang, Chuanhong Luo, Xiaoying Qian, Xinyuan Yao, Xin Ye, Biao Yu, Bingbiao Zhou, Dengying Chen, Chengsi Shu, Yong Wang, Yong Li
Saudi Medical Journal
Objectives: The process of analyzing tumor-associated neutrophils (TANs) types is complex. This study explored the relationships among clinicopathological characteristics, peripheral blood markers, and TANs. Methods: Clinical information was retrospective gathered for 115 patients in our hospital from May 2019 to May 2021, and multiplex immunofluorescence staining was utilized to access the expression of TANs and analyze the potential relationship between TANs and clinicopathological features or peripheral blood markers. Results: Among the 115 patients, the proportion of female patients within the neutrophils (N1)-low group was notably greater compared to the N1-high group (87.5% vs. 12.5%, p = 0.022). In nonsmoking patients, …
Clinical Role Of Hematologic Inflammatory Markers In The Diagnosis Of Missed Abortion, Mustafa Bakırcı, Çağlayan Ateş, Ethem S. Yalvaç
Clinical Role Of Hematologic Inflammatory Markers In The Diagnosis Of Missed Abortion, Mustafa Bakırcı, Çağlayan Ateş, Ethem S. Yalvaç
Saudi Medical Journal
Objectives: To evaluate the diagnostic value of hematological and biochemical inflammatory markers in distinguishing missed abortions from healthy pregnancies during the first trimester. Methods: This retrospective case-control study was conducted between May 2022 and May 2024, included 61 women diagnosed with missed abortion by ultrasound and 100 healthy pregnant women who acted as controls. The following inflammatory markers were calculated from routine blood and biochemistry results: neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), monocyte-lymphocyte ratio (MLR), lymphocyte-monocyte ratio (LMR), systemic immune-inflammation index (SII) and C-reactive protein-albumin ratio (CAR). Intergroup comparisons and receiver operating characteristic (ROC) curve analyses were performed. Results: The …
Concurrent Appendectomy In Patients Undergoing Surgery For Gynecological Malignancies: A Retrospective Analysis From A Tertiary Referral Center, Gazi Güner, Can Tercan, Emrah Dağdeviren, Ali Selçuk Yeniocak, Ceylin Elbistanli, Sure Nur Erdoğmuş, Ayşe Hazirbulan, Yiğit Mert Bayrak, Neçirvan Çağdaş Çaltek, Gözde Şahin, Ergun Tercan, Figen Efe Çamili, Nazlıaylin Vural, Hüseyin Karatay, Saniye Merve Gül Kara, İlkbal Temel Yüksel
Concurrent Appendectomy In Patients Undergoing Surgery For Gynecological Malignancies: A Retrospective Analysis From A Tertiary Referral Center, Gazi Güner, Can Tercan, Emrah Dağdeviren, Ali Selçuk Yeniocak, Ceylin Elbistanli, Sure Nur Erdoğmuş, Ayşe Hazirbulan, Yiğit Mert Bayrak, Neçirvan Çağdaş Çaltek, Gözde Şahin, Ergun Tercan, Figen Efe Çamili, Nazlıaylin Vural, Hüseyin Karatay, Saniye Merve Gül Kara, İlkbal Temel Yüksel
Saudi Medical Journal
Objectives: To evaluate appendectomy specimen findings and their association with tumor type and stage. Concurrent appendectomy is frequently performed during gynecologic oncology surgery to prevent postoperative appendicitis and detect occult pathology, yet its value remains debated. Methods: In this study, we reviewed the medical records of 300 women who underwent gynecologic oncologic surgery accompanied by appendectomy at Başakşehir Çam and Sakura City Hospital (Istanbul, Türkiye) over the period from July 2020 to April 2025. Clinical, surgical, andhistopathologic data were collected. Appendiceal pathologies were categorized as reactive hyperplasia, chronic inflammation, benign neoplasms, metastatic tumors, or primary. Statistical analyses included chi-square, t-test, …
Reliability And Validity Of The Arabic Version Of The Nose-Perf Scale, Rayan M. Alfallaj, Abdullah I. Binghaith, Mohammed Y. Alyoussef, Ahmed S. Alsaleh, Saad A. Alsaleh, Abdulaziz A. Alqahtani, Ahmad S. Alroqi
Reliability And Validity Of The Arabic Version Of The Nose-Perf Scale, Rayan M. Alfallaj, Abdullah I. Binghaith, Mohammed Y. Alyoussef, Ahmed S. Alsaleh, Saad A. Alsaleh, Abdulaziz A. Alqahtani, Ahmad S. Alroqi
Saudi Medical Journal
Objectives: To assess the psychometric validity of the Arabic adaptation of the nasal obstruction symptom evaluation–perforation (NOSE-Perf) scale. To assess how reliable and valid the Arabic adaptation of the NOSE-Perf questionnaire is. Patients with septal perforations, particularly Arabic speakers, lack validated self-assessment tools for subjective symptom evaluation. Methods: Conducted between May 2024 and June 2025, the study included 100 participants—20 patients with septal perforation and 80 controls. Participants filled out a questionnaire consisting of demographic data as well as the Arabic forms of the Sino-Nasal Outcome Test-22 (SNOT-22), NOSE, and NOSE-Perf scales. Cronbach's alpha was applied to determine internal consistency, …
A Multi-Centre Study: Quantitative Evaluation Of Radiation Dose For Adults Head Computed Tomography, Abdulaziz A. Qurashi, Shrooq T. Aldahery
A Multi-Centre Study: Quantitative Evaluation Of Radiation Dose For Adults Head Computed Tomography, Abdulaziz A. Qurashi, Shrooq T. Aldahery
Saudi Medical Journal
Objectives: To determine regional radiation dose in adults head computed tomography (CT) examinations in Jeddah by assessing the volume computed tomography dose index (CTDIvol) and dose length product (DLP) values. Methods: A retrospective study was conducted from February to April 2025 across 10 CT scanners from 5 governmental hospitals in Jeddah. Data for 20 head CT examinations per scanner were collected. Dose metrics including CTDIvol and DLP (mGy·cm), were extracted from digital imaging and communications in medicine (DICOM) images. Mean values per scanner and the 75th percentile were calculated across centres to identify the regional DRL. …
The Role Of The Delta Neutrophil Index In Determining The Severity Of Intrahepatic Cholestasis Of Pregnancy, Selçuk Atalay, Melike Çaltekin, Nihal Çallıoğlu, Fırat Ersan, Verda Alpay, Yasin Anasız, Ipek Geyikoğlu
The Role Of The Delta Neutrophil Index In Determining The Severity Of Intrahepatic Cholestasis Of Pregnancy, Selçuk Atalay, Melike Çaltekin, Nihal Çallıoğlu, Fırat Ersan, Verda Alpay, Yasin Anasız, Ipek Geyikoğlu
Saudi Medical Journal
Objective: This study aimed to investigate the clinical utility of the delta neutrophil index (DNI) in distinguishing patients with intrahepatic cholestasis of pregnancy (ICP) from healthy pregnant women, and to assess its potential role in evaluating disease severity. Methods: This retrospective analysis included data from 249 pregnant women. Among them, 131 were identified with ICP, based on clinical symptoms and total bile acid levels ≥ 10 μ mol/L. The remaining 118 participants served as healthy controls. The ICP cases were categorized into mild (TBA 10–39 μ mol/L; n = 90) and severe (TBA ≥ 40 μ mol/L; n = 41) …
Integrative Approaches To Gut Microbiota: Biomarkers, Dysbiosis, And Therapeutic Potential, Zeyad M. Alharbi
Integrative Approaches To Gut Microbiota: Biomarkers, Dysbiosis, And Therapeutic Potential, Zeyad M. Alharbi
Saudi Medical Journal
The human gut contains bacteria, viruses, and archaea that influence health depending on age, diet, and location. An individual harbours about 150 bacterial species. An imbalance of these microorganisms, known as dysbiosis, can negatively impact health. Commensal bacteria maintain microbial homeostasis by building short chain fatty acids. The 2-way communication channel that connects the gut and the brain is referred to as the gut-brain axis. Dysbiosis of the gut leads to some autoimmune diseases. A decline of beneficial bacteria causes the progression of rheumatoid arthritis. Gut dysbiosis increases intestinal permeability, allowing toxins and cytokines to enter the bloodstream and damage …
Emerging Nanotherapy Applications In Cancer Treatment: A Comprehensive Review, Waleed H. Mahallawi
Emerging Nanotherapy Applications In Cancer Treatment: A Comprehensive Review, Waleed H. Mahallawi
Saudi Medical Journal
This comprehensive review synthesizes recent advances in cancer nanotherapy, focusing on 6 emerging categories: immunomodulation, gene/RNA delivery, theranostics, radiosensitization, biomimetic carriers, and artificial intelligence (AI)-guided formulations. These innovative platforms demonstrate transformative potential by overcoming key limitations of conventional cancer treatments. Immunomodulatory nanoparticles reprogram tumor microenvironments and convert immunologically ``cold'' tumors to ``hot'' responsive states. Gene delivery systems enable precise editing with >50% efficiency, while theranostic platforms integrate real-time imaging with targeted therapy. Radiosensitizers amplify local radiation dose by twofold, and biomimetic carriers achieve prolonged circulation through immune evasion. An AI-driven approaches optimize personalized formulations based on patient-specific biomarkers. Clinical evidence …
Treatment Of Odontogenic Sinusitis With Oroantral Communication And Fistula: A Systematic Review And Meta-Analysis, Rana R. Alharbi, Omar F. Alnajar, Reham E. Almahdi, Salman A. Alrougi, Remas A. Alshehri, Ruyuf A. Alotaibi, Shahad S. Alharbi, Manal A Eltahir, Yahya A. Fageeh
Treatment Of Odontogenic Sinusitis With Oroantral Communication And Fistula: A Systematic Review And Meta-Analysis, Rana R. Alharbi, Omar F. Alnajar, Reham E. Almahdi, Salman A. Alrougi, Remas A. Alshehri, Ruyuf A. Alotaibi, Shahad S. Alharbi, Manal A Eltahir, Yahya A. Fageeh
Saudi Medical Journal
Objective: To assess the available data regarding medicinal, surgical, and combination therapy approaches for odontogenic sinusitis linked to OAC and OAF. Oroantral communication (OAC), an atypical connection between the oral cavity and maxillary sinus, commonly arises following upper jaw procedures, trauma, or infection. Chronic odontogenic maxillary sinusitis may result from OAC developing into an oroantral fistula (OAF) if treatment is not received. Recurrent infections and functional difficulties can be avoided by managing these illnesses effectively. Methods: A systematic search was conducted in National Library of Medicine's (PubMed [MEDLINE]) and Google Scholar for studies published between 2000 and 2024. A total …
Mental Health In Relation To Parental Absence: A Systematic Review, Mohammed Barry, Abdulaziz Alyahyawi, Heba Jafar Sabbagh
Mental Health In Relation To Parental Absence: A Systematic Review, Mohammed Barry, Abdulaziz Alyahyawi, Heba Jafar Sabbagh
Saudi Medical Journal
Objective: To evaluate the literature based on the relationship between orphaned children and mental health, compared to non-orphaned children. Mental well-being of orphaned children is a profound intricate topic that connects with broader concerns of childcare. This systematic review aims to evaluate the literature regarding the relationship between mental health and parental absence. Methods: We conducted a systematic search of PubMed, MEDLINE, and Science Direct in October 2025, with 1017 screened studies. Six studies met the inclusion criteria. Independent reviewers performed quality assessments using the Newcastle-Ottawa scale (NOS). Subsequently, a meta-analysis was performed when possible. Results: Findings indicate that orphaned …
Bilateral Lower Palpebral Conjunctival Protrusion In A Patient With Traumatic Unilateral Carotid-Cavernous Fistula, Sharfuddin M. Chowdhury, Omar A. Ababtain
Bilateral Lower Palpebral Conjunctival Protrusion In A Patient With Traumatic Unilateral Carotid-Cavernous Fistula, Sharfuddin M. Chowdhury, Omar A. Ababtain
Saudi Medical Journal
No abstract provided.
Chronic Total Occlusion Percutaneous Coronary Intervention: A Consensus Of The National Heart Center In Collaboration With The Saudi Cto Club Of The Saudi Arabian Cardiac Interventional Society, Waqar H. Ahmed, Khalid Aljohani, Sultan Alotaibi, Motasem Alyamani, Mohammed Almohammadi, Ahmed Alhamami, Hani Abdelhadi, Owayed Alshammeri, Abdullah Alsaiedi, Abdulrahman Almoghairi, Abdulrahman Qahtani, Saleh Khouj, Shatha Alalawi, Walid Alharbi
Chronic Total Occlusion Percutaneous Coronary Intervention: A Consensus Of The National Heart Center In Collaboration With The Saudi Cto Club Of The Saudi Arabian Cardiac Interventional Society, Waqar H. Ahmed, Khalid Aljohani, Sultan Alotaibi, Motasem Alyamani, Mohammed Almohammadi, Ahmed Alhamami, Hani Abdelhadi, Owayed Alshammeri, Abdullah Alsaiedi, Abdulrahman Almoghairi, Abdulrahman Qahtani, Saleh Khouj, Shatha Alalawi, Walid Alharbi
Saudi Medical Journal
Objective: Chronic total occlusion (CTO) is one of the most complex and technically demanding percutaneous coronary interventions (PCI). Over the last two decades, technological and procedural advancements have significantly improved clinical outcomes. However, CTO-PCI practice and outcomes remain suboptimal with a lack of standardized approaches. Methods: The Saudi CTO Club has been actively working to enhance collaboration among CTO operators throughout the region. The National Heart Center (NHC), in collaboration with the Saudi Arabian Cardiac Interventional Society (SACIS), convened national experts to develop a consensus document and workflow for integrating CTO-PCI into clinical practice in Saudi Arabia. This consensus document …
Epidemiological Mapping Of Drug-Susceptible And Resistant Tuberculosis In 30 Who High-Burden Countries: Three Decades Of Gbd 2023 Trends, Projections To 2043 And Concordance With Who Estimates, Azfar A. Ishaqui, Salman A. Ahmad, Shoaib Alam, Narendar Kumar, Javeria Farooq, Khalid Orayj, Rabbiya Ahmad, Mohammed Zawiah, Mustapha Mohammed, Muhammad Imran, Asaad A. Asaad Khalil, Mohammed A. Kaddoura, Sultan M. Alshahrani, Adnan Iqbal, Muhammad B. Maqsood
Epidemiological Mapping Of Drug-Susceptible And Resistant Tuberculosis In 30 Who High-Burden Countries: Three Decades Of Gbd 2023 Trends, Projections To 2043 And Concordance With Who Estimates, Azfar A. Ishaqui, Salman A. Ahmad, Shoaib Alam, Narendar Kumar, Javeria Farooq, Khalid Orayj, Rabbiya Ahmad, Mohammed Zawiah, Mustapha Mohammed, Muhammad Imran, Asaad A. Asaad Khalil, Mohammed A. Kaddoura, Sultan M. Alshahrani, Adnan Iqbal, Muhammad B. Maqsood
Saudi Medical Journal
Objectives: Tuberculosis (TB) continues to drive infectious mortality worldwide. The study characterized the evolution of drug-susceptible TB (DS-TB), multidrug-resistant TB (MDR-TB), and extensively drug-resistant TB (XDR-TB) in 30 WHO high-burden countries, linking current patterns to long-term trends, age structure, and forward-looking scenarios to 2043. Methods: Using GBD 2023 estimates for 1990–2023, we extracted incidence, mortality, and DALYs as age-standardized rates (ASR) per 100,000 with 95% uncertainty intervals. Temporal dynamics were summarized with Estimated Annual Percent Change (EAPC) and extended linearly to 2043. GBD incidence and mortality were compared against WHO national TB series for 2010–2023. Results: Overall TB incidence ASR …
The Application Effect Of Modified Pressure-Reducing Fixation Protective Nasal Strip In The Nursing Care Of Patients Receiving High-Flow Nasal Cannula Therapy, Ying Zhou, Xuting He, Jianying Sang
The Application Effect Of Modified Pressure-Reducing Fixation Protective Nasal Strip In The Nursing Care Of Patients Receiving High-Flow Nasal Cannula Therapy, Ying Zhou, Xuting He, Jianying Sang
Saudi Medical Journal
Objective: To evaluate the efficacy of a modified pressure-reducing fixation protective nasal strip in preventing device-related pressure injuries and improving nursing outcomes in patients undergoing high-flow nasal cannula (HFNC) therapy. Methods: This study included 60 patients receiving HFNC therapy from January 2024 to September 2024. Participants were randomly divided into an observation group (n = 30), which used the modified decompression fixation protective nasal strip, and a control group (n = 30), which underwent standard care with hydrocolloid dressing protection. The study compared general demographic data, the interval between fixation strap changes, frequency of catheter position adjustments, skin management effectiveness …
Validity And Reliability Of The Arabic Voice Activity And Participation Profile (A-Vapp) Questionnaire, Nawaf S. Alqarni, Hamad F. Alrabiah, Nasser F. Alsunbul, Manal A. Bukhari, Mohamed Farahat, Mohammed Almohizea, Tamer A. Mesallam, Khalid H. Malki
Validity And Reliability Of The Arabic Voice Activity And Participation Profile (A-Vapp) Questionnaire, Nawaf S. Alqarni, Hamad F. Alrabiah, Nasser F. Alsunbul, Manal A. Bukhari, Mohamed Farahat, Mohammed Almohizea, Tamer A. Mesallam, Khalid H. Malki
Saudi Medical Journal
Objectives: The purpose of this study was to translate and validate the Voice Activity and Participation Profile (VAPP), a comprehensive tool for assessing the impact of voice disorders on daily life activities and social participation, into Arabic and to test its reliability among voice disorders patients in Riyadh, Saudi Arabia \looseness-1 Methods: A descriptive, questionnaire-based validation study was conducted at two university hospitals from December 2023 to September 2024. The VAPP was translated using forward and backward translation methods from English into Arabic. The questionnaire's reliability and internal consistency were assessed using Cronbach's alpha and test-retest reliability. To measure …
Stratifying Renal Risk In End-Stage Renal Disease: Evidence From A Population-Based Dialysis Registry In Northern Saudi Arabia, Reem Eltayeb, Naif K Binsaleh, Ghaida A Alsaif, Mona Hm Ahmed, Ahmed M Taha, Abdelhameed Abdelzaher, Zinab Alatawi
Stratifying Renal Risk In End-Stage Renal Disease: Evidence From A Population-Based Dialysis Registry In Northern Saudi Arabia, Reem Eltayeb, Naif K Binsaleh, Ghaida A Alsaif, Mona Hm Ahmed, Ahmed M Taha, Abdelhameed Abdelzaher, Zinab Alatawi
Saudi Medical Journal
Objectives: We examined the relationship of age, gender, smoking, nationality, and place of residence with renal dysfunction severity in end-stage renal disease (ESRD) patients. Methods: We performed a cross-sectional study of ESRD registry data collected from King Khalid Hospital in Hail, Saudi Arabia. Adults (≥ 15 years) treated from March 2023 - February 2024 were enrolled. Serum creatinine and urinary albumin concentrations were measured (based on primary [≥ 625 μmol/L and ≥ 18 mg/L, respectively] and sensitivity thresholds). Bivariate analyses, interaction testing, sensitivity models, and multivariable logistic regression were employed. Results: Of 212 patients (50.9% male), based on primary thresholds, …
Critically Ill Patients Presenting To The Emergency Department; Outcome Review In A Tertiary Care Center, Maan Jamjoom, Lina Sami Reda, Bsaim Abdulsalam Altirkistani, Samer Tariq Anwar Ahmed, Samer Ali Alasmari, Abdulrahman Adnan Almehmadi, Ahmad Loay Atiah, Faisal Abdulaziz Boker, Rand Ayman Maddah
Critically Ill Patients Presenting To The Emergency Department; Outcome Review In A Tertiary Care Center, Maan Jamjoom, Lina Sami Reda, Bsaim Abdulsalam Altirkistani, Samer Tariq Anwar Ahmed, Samer Ali Alasmari, Abdulrahman Adnan Almehmadi, Ahmad Loay Atiah, Faisal Abdulaziz Boker, Rand Ayman Maddah
Saudi Medical Journal
Objective: Critically ill patients presenting to the emergency department require prompt recognition and prioritized care due to the severity of their conditions. Reviewing their clinical outcomes helps guide future planning and resource allocation. This study aims to highlight the outcomes of patients triaged as CTAS I and II in the emergency department of a tertiary care center in Jeddah, Saudi Arabia. Methods: A single-center retrospective cohort study was conducted in the emergency department of a tertiary healthcare center, National Guard Health Affairs, in Jeddah. The study provides a comprehensive assessment of factors (including length of stay) and outcomes for a …