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Articles 781 - 810 of 7869
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Common Clinical Pattern Of Antineutrophil Cytoplasmic Antibody -Associated Vasculitis: An Experience From A Multicenter Study In Saudi Arabia, Jumanah J. Alfuwayris, Amal M. Almulhim, Mohammed A. Almansour, Marzouq A. Albadi, Ibrahim A. Alhomood, Faisal Alblewi, Abdullah U. Althemery
Common Clinical Pattern Of Antineutrophil Cytoplasmic Antibody -Associated Vasculitis: An Experience From A Multicenter Study In Saudi Arabia, Jumanah J. Alfuwayris, Amal M. Almulhim, Mohammed A. Almansour, Marzouq A. Albadi, Ibrahim A. Alhomood, Faisal Alblewi, Abdullah U. Althemery
Saudi Medical Journal
Objectives: To understand the most common type and clinical manifestations of associated vasculitis (AAV) in the Saudi Arabia. Methods: This retrospective study was conducted at King Fahad Medical City and the Security Forces Hospital Program, Riyadh, Saudi Arabia, between January 2014 and May 2022. Patients aged ≥18 years were included in the study and diagnosed based on clinical manifestations, serology, or histopathology according to the EMA algorithm. Univariate analysis was carried out to compare different groups; a series of independent samples t-tests was applied for continuous data. Results: A total of 53 patients were enrolled: eosinophilic granulomatosis with polyangiitis (EGPA), …
Clinical And Laboratory Characteristics Of Idiopathic Inflammatory Myositis In Saudi Patients: A Retrospective Study In A Single Tertiary Centre, Fahidah Alenzi, Jawaher Alotaibi, Manal Alnasser, Fahdah Alokaily
Clinical And Laboratory Characteristics Of Idiopathic Inflammatory Myositis In Saudi Patients: A Retrospective Study In A Single Tertiary Centre, Fahidah Alenzi, Jawaher Alotaibi, Manal Alnasser, Fahdah Alokaily
Saudi Medical Journal
Objectives: Idiopathic inflammatory myositis (IIM) in Saudi patients has been poorly studied owing to the lack of available data. This study aimed to identify the clinical and laboratory features of patients at a single tertiary care center. Methods: This retrospective study reviewed the medical records of Prince Sultan Military Medical City, Riyadh, Saudi Arabia to collect clinical and laboratory data between December 2022 and February 2023 as follows: age at disease onset, gender, follow-up duration and disease duration; clinical symptoms; laboratory result; presence and type of myositis-specific autoantibody or myositis-associated autoantibody; and type of immunosuppression, presence of malignancy, disease course, …
1 In 6 People Globally Affected By Infertility: Who
1 In 6 People Globally Affected By Infertility: Who
Saudi Medical Journal
No abstract provided.
The Cholera Emergency Is Avoidable
Potential Therapeutic Benefit Of Ursodeoxycholic Acid In The Management Of Non Hepato-Biliary Upper Gastrointestinal Disorders, Yasir M. Khayyat
Potential Therapeutic Benefit Of Ursodeoxycholic Acid In The Management Of Non Hepato-Biliary Upper Gastrointestinal Disorders, Yasir M. Khayyat
Saudi Medical Journal
Objectives: To examine the potential therapeutic effects of ursodeoxycholic acid (UDCA) on diseases of the esophagus, stomach, and duodenum. Methods: A search was conducted using EBSCO, Medline, PubMed, Google Scholar and Web of Science as well as international guidelines using MESH terms for treatment of UDCA for diseases of the upper gastrointestinal disorders in adult humans without regard to publication language or date restrictions. Results: A total of 256 articles and 22 guidelines were initially identified, and 221 were excluded. Final revision of 13 articles and 22 guidelines confirmed that UDCA is found to have a cytoprotective role in Barret’s …
Patient Comfort In Percutaneous Coronary Interventions, Buse Çıracı, Selda Rızalar
Patient Comfort In Percutaneous Coronary Interventions, Buse Çıracı, Selda Rızalar
Saudi Medical Journal
Objectives: To identify patients’ general comfort levels in percutaneous coronary intervention. Methods: This descriptive research included 2 hundred cardiac patients, whom were in the Medipol Mega University Hospital, Istanbul, during the period between May 2018 and May 2019. The data were obtained by General Comfort Questionnaire and evaluated using mean, standard deviation, percentage and t-test. Results: In this study reports that patients had the mean total comfort score as 3.03±0.3. They acquired the maximum score from the psychospiritual comfort subdimension and the minimum score from the physical comfort subdimension. Patients who experienced transradial percutaneous coronaryintervention had statistically higher general, physical, …
Clinical And Pathological Characteristics Of Extra-Cranial Germ Cell Tumors: A 30-Year Single-Center Experience In Saudi Arabia, Dania A. Monagel, Aletani Tala, Alghamdi Arwa, Banjar Sereen, Hakeem Ilana, Hannef Deena, Ahmed Omaima, Elimam Naglla
Clinical And Pathological Characteristics Of Extra-Cranial Germ Cell Tumors: A 30-Year Single-Center Experience In Saudi Arabia, Dania A. Monagel, Aletani Tala, Alghamdi Arwa, Banjar Sereen, Hakeem Ilana, Hannef Deena, Ahmed Omaima, Elimam Naglla
Saudi Medical Journal
Objectives: To investigate the clinical and pathological characteristics of extracranial germ cell tumors (GCTs) in children aged 0–168 months treated at the National Guard Hospital, Jeddah, Saudi Arabia from 1990 to 2020. Methods: In this retrospective analysis, the data for all cases of GCTs were collected from 1990 to 2020. Statistical analyses were carried out using JMP software. The data was divided into 4 main categories: demographics, pathological/clinical features, recurrence, treatment and outcome. Results: The study included 50 patients, with a mean age at diagnosis of 56.52 months. The median follow-up duration was 30 months. Most tumors were in the …
The Prevalence And Risk Factors For Hiatal Hernia Among Patients Undergoing Endoscopy: A Retrospective Analysis, Majid A. Alsahafi, Najla A. Alajhar, Amjad O. Almahyawi, Hadeel H. Alsulami, Wejdan A. Alghamdi, Lama A. Alharbi, Afnan S. Alsulami, Jumana T. Aljehani, Saad S. Alkhowaiter, Mahmoud H. Mosli
The Prevalence And Risk Factors For Hiatal Hernia Among Patients Undergoing Endoscopy: A Retrospective Analysis, Majid A. Alsahafi, Najla A. Alajhar, Amjad O. Almahyawi, Hadeel H. Alsulami, Wejdan A. Alghamdi, Lama A. Alharbi, Afnan S. Alsulami, Jumana T. Aljehani, Saad S. Alkhowaiter, Mahmoud H. Mosli
Saudi Medical Journal
Objectives: To determine the prevalence of hiatal hernia (HH) and its association with age, gender, and body mass index (BMI). Methods: We retrospectively included patients who underwent esophagogastroduodenoscopy (EGD) at an academic tertiary care hospital. Data were collected on the presence of HH as well as patient demographics including age, gender, and BMI. Univariate and multivariate analysis were done to determine risk factors for HH. Results: A total of 2805 patients were included in this study. The mean age was 48.6 (±18.6) years and males constituted 28.8% of the study population. The mean BMI was 29.7 (±8.6) kg/m². The prevalence …
Levels And Profiles Of Pentabromodiphenyl Ether Contaminants In Human Breast Milk From Riyadh, Saudi Arabia, Sobhy M. Yakout, Ahmed M. Isa, Amel A. El-Sayed, Ibrahim M. Aziz
Levels And Profiles Of Pentabromodiphenyl Ether Contaminants In Human Breast Milk From Riyadh, Saudi Arabia, Sobhy M. Yakout, Ahmed M. Isa, Amel A. El-Sayed, Ibrahim M. Aziz
Saudi Medical Journal
Objectives: To investigate levels of pentabromodiphenyl ether (PBDEs) in breast milk samples from healthy mothers who had lived in Riyadh for the last 5 years. Methods: In this cross sectional study, 75 samples were collected and were extracted, cleaned by solid-phase extraction (SPE) and PBDEs analysis was done using gas chromatography–mass spectrometry. Results: Total PBDEs (∑PBDEs) ranged from 0.2 to 3.6 ng/g lipid weight (lw). BDE-47, -153, -99, and -209 were the dominant congeners. The mothers in this study consumed more meat (69%), followed by the egg (50%), and milk (36%). The majority of donors consumed fish (44%) and egg …
Management And Clinical Outcomes Of Cardiogenic Shock In King Abdulaziz University Hospital: A Retrospective Study, Hamza L. Fida, Mohammed A. Qutub, Alaa S. Algazzar, Abdulrahman S. Aldharrab, Terad A. Alnajjar, Anas M.A. Andijani, Ahmad M. Taiyeb
Management And Clinical Outcomes Of Cardiogenic Shock In King Abdulaziz University Hospital: A Retrospective Study, Hamza L. Fida, Mohammed A. Qutub, Alaa S. Algazzar, Abdulrahman S. Aldharrab, Terad A. Alnajjar, Anas M.A. Andijani, Ahmad M. Taiyeb
Saudi Medical Journal
Objectives: To assess frequencies of various management approaches in cardiogenic shock (CS) and their clinical outcomes. Cardiogenic shock is a state of organ hypoperfusion and hypoxia caused by cardiac failure. Methods: In this retrospective record review, we assessed the presentations, vital signs, laboratory readings, and treatments for 188 consecutive CS inpatients from 2010-2021. Patients were labeled as “ischemic CS” or “non-ischemic CS” based on the occurrence of myocardial infarction as the precipitating cause, and “post-operative CS” if they had undergone cardiac surgery. In-hospital mortality was the primary endpoint of the study. Results: We identified 118 (62.8%) ischemic, 64 (34%) non-ischemic, …
Is Metabolic Syndrome A Modifiable Risk Factor For Gout?
Is Metabolic Syndrome A Modifiable Risk Factor For Gout?
Saudi Medical Journal
No abstract provided.
Estimating The Prevalence Of Pediatric Hematological Malignancies In Al-Madinah Al-Munawwarah, Saudi Arabia, Faisal S. Alhajori, Mohammed H. Makkawi, Sultan Z. Alasmari, Ahmad A. Shaikh, Mirza A. Baig
Estimating The Prevalence Of Pediatric Hematological Malignancies In Al-Madinah Al-Munawwarah, Saudi Arabia, Faisal S. Alhajori, Mohammed H. Makkawi, Sultan Z. Alasmari, Ahmad A. Shaikh, Mirza A. Baig
Saudi Medical Journal
Objectives: To provide an updated estimate to the prevalence of pediatric hematological malignancies (HMs) in the Al-Madinah Al-Munawwara, Saudi Arabia. Methods: This is a retrospective study that was carried out between 2016 and 2022. The study population was comprised of 171 children under 16 who had been diagnosed with HMs. The data was compiled from King Salman Medical City’s Maternity and Children’s Hospital, Al-Madinah Al-Munawwarah, Saudi Arabia. Results: Among the 171 HM patients (64% males and 36% females), 13 subtypes were identified, with B-cell acute lymphoblastic leukemia having the highest incidence (70.3%). Acute myelomonocytic leukemia (8.7%), T-cell acute lymphoblastic leukemia …
To Drain Or Not To Drain Following Thyroidectomy.: A Prospective, Randomized Study, Nidhi Mariam George, Tharun Ganapathy Chitrambalam, Pradeep Joshua Christopher, Manish Marlecha, Sundeep Selvamuthukumaran
To Drain Or Not To Drain Following Thyroidectomy.: A Prospective, Randomized Study, Nidhi Mariam George, Tharun Ganapathy Chitrambalam, Pradeep Joshua Christopher, Manish Marlecha, Sundeep Selvamuthukumaran
Saudi Medical Journal
Objectives: To ascertain the use of draining the thyroid bed following surgery. Methods: Fifty four patients who underwent total thyroidectomy were enrolled in the study between March 2021 and July 2022 and randomly allocated into 2 groups – a drain group and a no drain group. The hospital stay, operating time, post operative pain, post operative complications, cosmesis, and patient’s perspectives were compared. Results: The mean duration of hospitalization was significantly shorter in the no drain group as compared to the drain group. The post operative pain, as assessed by the Mankoski Pain Scale (MPS) was significantly higher in the …
Predictive Value Of Triglycerides To High Density Lipoprotein Ratio In Patients With First Attack Of Acute Coronary Syndrome, Abdullah S. Basuliman, Mohammed A. Malabarey, Fahad W. Abousamak, Bader Y. Alyousef, Saleh S. Alrabea, Rakan A. Alshabibi
Predictive Value Of Triglycerides To High Density Lipoprotein Ratio In Patients With First Attack Of Acute Coronary Syndrome, Abdullah S. Basuliman, Mohammed A. Malabarey, Fahad W. Abousamak, Bader Y. Alyousef, Saleh S. Alrabea, Rakan A. Alshabibi
Saudi Medical Journal
Objectives: To identify patients who are at risk for a first cardiovascular event, mitigate the risk, and institute early intervention. The triglyceride to high-density lipoprotein-C (TG/HDL-C) ratio has been found to be a very useful biomarker for directing treatment and prevention therapy. Methods: This retrospective cross-sectional study included adult patients (aged >18 years) experiencing first-time acute coronary syndrome (ACS). We examined all patient databases for a definite diagnosis of angina, non-ST segment elevation myocardial infarction (NSTEMI), or ST-segment elevation myocardial infarction (STEMI). Lipid profiles were obtained prior to or at the time of admission. Results: A total of 265 patients …
Frequency Of The Rs2015 (T>G) And Rs2241703 (G>A) Polymorphisms In The Mirna-Sirt2 Gene In Type 2 Diabetes Mellitus In Saudi Arabia, Nahla A. Alshaikh, Siddig I. Abdelwahab, Mahmoud M. Habibullah, Ahmed A. Jerah, Mohammed A. Bakri, Yahia A. Kaabi
Frequency Of The Rs2015 (T>G) And Rs2241703 (G>A) Polymorphisms In The Mirna-Sirt2 Gene In Type 2 Diabetes Mellitus In Saudi Arabia, Nahla A. Alshaikh, Siddig I. Abdelwahab, Mahmoud M. Habibullah, Ahmed A. Jerah, Mohammed A. Bakri, Yahia A. Kaabi
Saudi Medical Journal
Objectives: To investigate the prevalence of rs2015 (T>G) and rs2241703 (G>A) polymorphisms in the miRNA-SIRT2 gene in Saudi Arabia and their possible associations with type 2 diabetes mellitus (T2DM). Methods: Blood samples were collected from 428 participants from Jazan University Hospital, Jazan, Saudi Arabia between September 2021 and June 2022 and subjected to TaqMan single-nucleotide polymorphisms (SNP) genotyping assay for rs241703 (G>A) and rs2015 (G>T). Genotype frequencies were determined in control (n=217). Results: The A allele of rs2241703 was undetected in our population, and all samples carried the GG genotype. The rs2015 SNP frequency was 29.4% …
Surgicel Plug Technique Versus Endoclose Technique For Port-Site Closure Post Minimally Invasive (Robotic And Laparoscopic) Surgeries: Retrospective Cohort Study, Maher S. Moazin, Abdulrahman M. Alsuwailim, Mosab M. Botaiban, Abdulaziz Y. Alabdulrahman, Abdullah Alfakhri, Naif Aldhaam,, Muhammad Abukhater, Arjmand Reyaz, Mohammed Y. Alessa
Surgicel Plug Technique Versus Endoclose Technique For Port-Site Closure Post Minimally Invasive (Robotic And Laparoscopic) Surgeries: Retrospective Cohort Study, Maher S. Moazin, Abdulrahman M. Alsuwailim, Mosab M. Botaiban, Abdulaziz Y. Alabdulrahman, Abdullah Alfakhri, Naif Aldhaam,, Muhammad Abukhater, Arjmand Reyaz, Mohammed Y. Alessa
Saudi Medical Journal
Objectives: To compares the endoclose technique (ET) techniques and surgicel plug technique (SPT) in terms of port-site related complications. Minimally invasive surgeries (MIS) are widely performed nowadays, nonetheless, port-site closure technique plays a role in the prevention of port-site related complications. Methods: This retrospective study was carried out at general surgery and urology departments of King Fahad Medical City, Saudi Arabia. Variables that were collected include age, gender, height, weight, body mass index, co-morbidities, type and date of surgery, intraoperative visceral injury or bleeding, technique cost, and port-site post-operative complications (hernia, infection, bleeding, dehiscence, and hypertrophic scarring). Data was collected …
Demographic And Clinical Profile Of Patients With Chronic Rhinosinusitis In Saudi Arabia, Rayan Alfallaj, Sultan Bin Obaid, Hisham Almousa, Dawood Ismail, Saleh Mahjoub, Fatma Alanazy, Surayie Al Dousary, Saud Alromaih, Mohammad Aloulah, Abdulaziz Alrasheed, Ahmad S. Alroqi, Saad Alsaleh
Demographic And Clinical Profile Of Patients With Chronic Rhinosinusitis In Saudi Arabia, Rayan Alfallaj, Sultan Bin Obaid, Hisham Almousa, Dawood Ismail, Saleh Mahjoub, Fatma Alanazy, Surayie Al Dousary, Saud Alromaih, Mohammad Aloulah, Abdulaziz Alrasheed, Ahmad S. Alroqi, Saad Alsaleh
Saudi Medical Journal
Objectives: To determine the clinical features of patients with chronic rhinosinusitis at a tertiary hospital in Riyadh, Saudi Arabia. Methods: A cross-sectional study was carried out at King Abdulaziz University Hospital, Riyadh, Saudi Arabia. We enrolled 660 male and female participants with medical records indicating a history of chronic rhinosinusitis between 2021 and 2022. Quantitative and descriptive analyses of age, gender, nationality, presence of polyps, aspirin sensitivity, presence of urticaria, asthma, and allergies were performed. Results: Of the 660 enrolled patients, 60% (n=396) were male and 40% (n=264) were female. Additionally, 67.7% (447) had nasal polyps, 32% had a history …
Can Moderate Dietary Salt Restriction Help Patients With Hypertension?
Can Moderate Dietary Salt Restriction Help Patients With Hypertension?
Saudi Medical Journal
No abstract provided.
Statement On The Update Of Who’S Working Definitions And Tracking System For Sars-Cov-2 Variants Of Concern And Variants Of Interest
Saudi Medical Journal
No abstract provided.
In This Issuesystematic Revieworiginal Articles
In This Issuesystematic Revieworiginal Articles
Saudi Medical Journal
No abstract provided.
The Histopathological Effects Of Sleep Disorders On Striated Muscle In Rats, İlkay Çinar, Muhammed Bozoğlan, Kürşad Aytekin, Deniz Esenyel, Cem Zeki Esenyel
The Histopathological Effects Of Sleep Disorders On Striated Muscle In Rats, İlkay Çinar, Muhammed Bozoğlan, Kürşad Aytekin, Deniz Esenyel, Cem Zeki Esenyel
Saudi Medical Journal
Objectives: To histopathologically examine the change in gastrocnemius muscle created by sleep disorder in rats. Methods: This study was carried out at Giresun University, Turkey from December 2018 to January 2021. A total of 30 Wistar rats were separated into 3 groups as the control group (CG), absence of rapid eye movement (REM) sleep (ARS) group, chronic absence of sleep (CAS) group. The lack of sleep was created in all rats. At the end of 21 days, all the rats were euthanized. Degeneration and regeneration findings, and expressions of muscle RING finger 1 (MuRF1), muscle atrophy F-box (MAFbx), tumor necrosis …
Clinicopathologic Characteristics And Outcomes Of Patients With Mycosis Fungoides: A Single Tertiary Center Retrospective Analysis In Saudi Arabia, Faisal A. Alghubaywi, Sawsan A. Alharthi, Sarah S. Aldharman, Raneem H. Najjar, Majed Y. Aleissa, Ohoud Z. Aljarbou, Mohammed I. Aljasser, Mohammad A. Almohideb
Clinicopathologic Characteristics And Outcomes Of Patients With Mycosis Fungoides: A Single Tertiary Center Retrospective Analysis In Saudi Arabia, Faisal A. Alghubaywi, Sawsan A. Alharthi, Sarah S. Aldharman, Raneem H. Najjar, Majed Y. Aleissa, Ohoud Z. Aljarbou, Mohammed I. Aljasser, Mohammad A. Almohideb
Saudi Medical Journal
Objectives: To determine the distinctive clinical and pathological characteristics and outcomes of MF in a Saudi population. Methods: We conducted a retrospective analysis of all MF cases diagnosed clinically with pathological confirmation at King Abdulaziz Medical City in Riyadh from January 2016 to July 2022. Variables include demographical, clinical, and pathological MF traits and disease outcomes. Results: A sum of 73 patients were enrolled. The mean age was 44 years. The female-to-male ratio was 1.3:1. The mean duration between cutaneous manifestations and MF diagnosis was 33 months (2.7 years). Classic MF was the most common variant (60.3%), followed by hypopigmented …
Prevalence, Hematological Parameters, And Coagulation Profiles: Cardiovascular Diseases Statistics In The Asir Region, Saudi Arabia, Kholoud N. Almetairi, Sultan Z. Alasmari, Mohammed H. Makkawi, Ahmad A. Shaikh
Prevalence, Hematological Parameters, And Coagulation Profiles: Cardiovascular Diseases Statistics In The Asir Region, Saudi Arabia, Kholoud N. Almetairi, Sultan Z. Alasmari, Mohammed H. Makkawi, Ahmad A. Shaikh
Saudi Medical Journal
Objectives: To determine the prevalence of cardiovascular disease (CVD) types in the Asir region of Saudi Arabia and the importance of hematological testing for CVD patients in the context of disease management. Methods: This retrospective study comprised 416 CVD patients, and samples were divided based the type of CVD. The Mann Whitney U test was used to compare patients’ hematological markers and coagulation profiles to those of healthy controls. Results: The rate of ischemic heart disease (IHD) was 80.7% that of other CVDs, and the rate of ST-elevation myocardial infarction (STEMI) was 37.3% the rate of CVD. Significant differences were …
Potential Barriers To The Daily Use Of Hearing Aids In Children, Medhat F. Yousef, Ziyad I. Dhayan, Tahera Islam, Fahad Z. Alotabi, Eman A Hajr
Potential Barriers To The Daily Use Of Hearing Aids In Children, Medhat F. Yousef, Ziyad I. Dhayan, Tahera Islam, Fahad Z. Alotabi, Eman A Hajr
Saudi Medical Journal
Objectives: To identify factors affecting hearing aid usage in children. Methods: This retrospective study examined 59 hearing-impaired children fitted with hearing aids for at least 6 months. Patients with moderate to profound sensorineural hearing loss with complete data-logging information stored in the hearing aid programming file from January 2020 until June 2021 were included. Children with concomitant disabilities were excluded. Data for audiological assessments included hearing assessment, aided hearing thresholds, and aided speech tests. Results: The children’s age ranged from 6 months to 6 years. Average daily hearing aid usage was 5.5 hour (h) after 3 months, 7 h after …
Systematic Review And Pooled Analysis Of Randomized Controlled Trials In Countries Of The Gulf Cooperation Council (Gcc): Methods And Quality Assessment, Khalid S. Alraddadi, Fayzah H. Al-Adwani, Rajaa M. Al-Raddadi, Sultan H. Alamri, Iman K. Ramadan, Ahmad A. Mirza
Systematic Review And Pooled Analysis Of Randomized Controlled Trials In Countries Of The Gulf Cooperation Council (Gcc): Methods And Quality Assessment, Khalid S. Alraddadi, Fayzah H. Al-Adwani, Rajaa M. Al-Raddadi, Sultan H. Alamri, Iman K. Ramadan, Ahmad A. Mirza
Saudi Medical Journal
Objectives: To describe variations in characteristics of randomized controlled trials conducted in the Gulf Cooperation Council (GCC) countries, and critically appraising the quality of design, conduct and analysis of the trials. Methods: We carried out a systematically comprehensive electronic search of articles published between 1990 and 2018 and indexed in several databases: i) MEDLINE/PubMed, ii) EMBASE, iii) Cochrane Central Register of Controlled Trials (CENTRAL), iv) ClinicalTrials.gov, and v) World Health Organization International Clinical Trials Registry Platform. We summarized the overall risk of bias present in all analyzed studies using the Cochrane Collaboration risk of bias tool (CCRBT). Results: A remarkable …
Does Birth By Cesarean Section Affect Children’S Academic Performance And Intelligence?
Does Birth By Cesarean Section Affect Children’S Academic Performance And Intelligence?
Saudi Medical Journal
No abstract provided.
Cellular Resistance Mechanisms In Cancer And The New Approaches To Overcome Resistance Mechanisms Chemotherapy, Ali A. Rabaan
Cellular Resistance Mechanisms In Cancer And The New Approaches To Overcome Resistance Mechanisms Chemotherapy, Ali A. Rabaan
Saudi Medical Journal
Despite major advancements in cancer healing approaches over the last few decades, chemotherapy remains the most popular malignancy treatment. Chemotherapeutic drugs are classified into many kinds based on their mechanism of action. Multidrug resistance (MDR) is responsible for approximately 90% of fatalities in malignancy cases treated with standard chemotherapeutics or innovative targeted medicines. Many innovative prospective anti-cancer medicines displayed high anti-cancer efficacy in a single application. However, combining them with other medications improves cancer treatment efficacy. This supports the belief that a combination of drugs is significantly more effective than a single medicine. Due to the intricacy of MDR processes …
1 In 6 People Globally Affected By Infertility: Who
1 In 6 People Globally Affected By Infertility: Who
Saudi Medical Journal
No abstract provided.
The Impact Of Viability Assessment Using Cardiac Mri And Echocardiogram On The Outcome Of Revascularization In Patients With Multi-Vessels Coronary Artery Disease And Moderate To Severe Ischemic Cardiomyopathy, Atif Alzahrani, Hani Mufti, Anas Alswat, Bsaim Altirkistani, Mohammed Aljehani, Ahmed Jazzar, Fahad Alutaibi, Amir Abushouk, Jamilah Al Rahimi, Wail Al Kashkari, Mohammed Althobaiti
The Impact Of Viability Assessment Using Cardiac Mri And Echocardiogram On The Outcome Of Revascularization In Patients With Multi-Vessels Coronary Artery Disease And Moderate To Severe Ischemic Cardiomyopathy, Atif Alzahrani, Hani Mufti, Anas Alswat, Bsaim Altirkistani, Mohammed Aljehani, Ahmed Jazzar, Fahad Alutaibi, Amir Abushouk, Jamilah Al Rahimi, Wail Al Kashkari, Mohammed Althobaiti
Saudi Medical Journal
Objectives: To investigate the influence of viability assessment in the management of patients with ischemic cardiomyopathy (ICM). Methods: This retrospective cohort study included all patients with ICM with moderate to severely reduced left ventricular ejection fraction (LVEF) who underwent viability assessment using cardiac magnetic resonance imaging (MRI) and echocardiogram as modalities of imaging. In addition, LVEF, modality of choice, and treatment plans were all extracted as main variables from the electronic database. One hundred 6 patients who met the inclusion criteria from December 2014 to December 2019 were included. Results: Posttreatment LVEF improved by 5% in the viable group compared …
Vitamin D Status Among Residents Of Molidawa Daur Autonomous Banner, Inner Mongolia, North China, Jingwen Hu, Yunmei Liang, Guiping Wen, Dezhong Chen, Yuanjing Liu, Hongmei Zhang, Xiaosong Qin
Vitamin D Status Among Residents Of Molidawa Daur Autonomous Banner, Inner Mongolia, North China, Jingwen Hu, Yunmei Liang, Guiping Wen, Dezhong Chen, Yuanjing Liu, Hongmei Zhang, Xiaosong Qin
Saudi Medical Journal
Objectives: To retrospectively analyze the vitamin D (VD) status of residents in northeastern Inner Mongolia and its relationship with the average monthly sunshine hours. Methods: Serum 25-hydroxyvitamin D[s-25(OH)D] samples from 4982 outpatients (2092 males) in Moli Dawa Daur Autonomous Banner People’s Hospital, Hulunbuir, China from July 2018 to January 2022 were included in this study. Results: The overall median s-25(OH)D was 53.3 nmol/L, VD deficiency (<30 nmol/L), deficiency (30-50 nmol/L), sufficient (>50-250 nmol/L) and excess (>250 nmol/L) were 16% (796/4982), 30% (1495/4982), 53.4% (2658/4982) and 0.7% (33/4982). There were statistically significant differences in median s-25(OH)D by month, age-groups and gender ( p <0.001). Low VD status (LVDS, including VD deficiency and insufficiency) in females was 54.6% and males was 33.9%, and the LVDS composition differed significantly by age-group and month ( p <0.05). The changing trend of the median s-25(OH)D level was similar to the monthly average sunshine hours, with a slight lag. Conclusion: Nearly half of residents live in LVDS. LVDS is affected by month, gender, and age.