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An Unusual Presentation Of Metabolic Cardiomyopathy Due To Pompe's Disease, Poothirikovil Venugopalan, Shakeel Ahmed, Vasudev T. Rao, Khalid M. Al-Hinai
An Unusual Presentation Of Metabolic Cardiomyopathy Due To Pompe's Disease, Poothirikovil Venugopalan, Shakeel Ahmed, Vasudev T. Rao, Khalid M. Al-Hinai
Saudi Medical Journal
An Omani infant boy who presented in the neonatal period with cardiac failure secondary to hypertrophic cardiomyopathy is reported. He subsequently progressed to show features of a metabolic disorder with multisystem involvement and was diagnosed to have Type II glycogenosis (Pompe9s disease). The differential diagnosis and management of metabolic cardiomyopathy are outlined.
Non Operative Management Of Blunt Bile Duct Injuries In Children, Mohammed S. Mallick, Abdulrahman A. Al-Bassam, Ahmed A. Boukai
Non Operative Management Of Blunt Bile Duct Injuries In Children, Mohammed S. Mallick, Abdulrahman A. Al-Bassam, Ahmed A. Boukai
Saudi Medical Journal
Bile duct injuries after blunt abdominal trauma are rare in children. This report describes 2 cases of blunt bile duct injuries in children, which were managed non-operatively. One patient sustained partial tear in the right hepatic duct, which was managed successfully by passing a stent into the injured duct during endoscopic retrograde cholangio pancreatography. The 2nd patient had intrahepatic bile duct injury associated with liver trauma and was managed with a drain placed in the sub-hepatic area percutaneously. This non-operative management in our patients allowed healing of bile duct injuries without any stricture, at 2 years follow-up. Both children are …
Geriatric Care - A Challenge To Internists In Saudi Arabia, Latif A. Khan, Sarosh A. Khan
Geriatric Care - A Challenge To Internists In Saudi Arabia, Latif A. Khan, Sarosh A. Khan
Saudi Medical Journal
No abstract provided.
Acute Appendicitis Presenting As Urinary Retention: A Note Of Caution, Aws S. Salim, Talal M. Ahmed
Acute Appendicitis Presenting As Urinary Retention: A Note Of Caution, Aws S. Salim, Talal M. Ahmed
Saudi Medical Journal
No abstract provided.
Hydroxyurea In Sickle Cell Disease Patients From Eastern Saudi Arabia, Ali H. Al-Jam'a, Ibrahim A. Al-Dabbous
Hydroxyurea In Sickle Cell Disease Patients From Eastern Saudi Arabia, Ali H. Al-Jam'a, Ibrahim A. Al-Dabbous
Saudi Medical Journal
OBJECTIVE: To assess the efficiency and safety of hydroxyurea in patients with sickle cell disease from the Eastern Province, Kingdom of Saudi Arabia. METHODS: The study was an open-label and uncontrolled trial. Patients older than 10 years of age with sickle cell disease who suffered 4 or more episodes of painful vaso-occlusive crises requiring admissions per year were included, 36 patients (23 males and 13 females) were included between June 1994 and June 1998. Patients were started on hydroxyurea at a dose of 8-10mg/kg per day and the dose was escalated to a maximum tolerated dose or a dose of …
Efficacy Of Erythropoietin In Premature Infants, Adnan A. Amin, Daifulah M. Alzahrani
Efficacy Of Erythropoietin In Premature Infants, Adnan A. Amin, Daifulah M. Alzahrani
Saudi Medical Journal
OBJECTIVE: To identify the effect of early parental recombinant human erythropoietin and iron administration on the blood transfusion requirement of premature infants. METHODS: In a controlled clinical trial conducted at the neonatal intensive care unit of Al-Hada Military Hospital, Taif, Kingdom of Saudi Arabia over a 16 months period, we assigned 20 very low birth weight infants with gestational age of (mean ± standard error of mean) 28.4 ± 0.5 weeks and birth weight of (mean ± standard error of mean) 1031 ± 42 gm, to receive either intravenous recombinant human erythropoietin 200 U/kg/day and iron 1mg/kg/day or conventional therapy …
A New Focus Of Cutaneous Leishmaniasis Caused By Leishmania Tropica, Mohammad R. Yaghoobi-Ershadi, Ahmad A. Hanafi-Bojd, Ezzatodin Javadian, Reza Jafari, Ali R. Zahraei-Ramazani, Mehdi Mohebali
A New Focus Of Cutaneous Leishmaniasis Caused By Leishmania Tropica, Mohammad R. Yaghoobi-Ershadi, Ahmad A. Hanafi-Bojd, Ezzatodin Javadian, Reza Jafari, Ali R. Zahraei-Ramazani, Mehdi Mohebali
Saudi Medical Journal
OBJECTIVE: To determine the epidemiological status of the cutaneous leishmaniasis outbreak, isolation and identification of the parasite and preparation of a control program in a recently identified focus located in the Province of Yazd, Central Iran. METHODS: This study was conducted in 124 classrooms of primary school children and among 139 households of an infected quarter in the city of Yazd during 1999-2000. All the students and members of the households were questioned and examined for the presence of ulcer(s) or scar(s). For each case a form was completed and necessary information were recorded. Smears were prepared from the edge …
The Prevalence Of Hepatitis B Core Antibody Positivity In Donors For Liver Transplantation In Saudi Arabia, Mohammed I. Al-Sebayel, Hatem A. Khalaf, Carlo G. Ramirez
The Prevalence Of Hepatitis B Core Antibody Positivity In Donors For Liver Transplantation In Saudi Arabia, Mohammed I. Al-Sebayel, Hatem A. Khalaf, Carlo G. Ramirez
Saudi Medical Journal
OBJECTIVE: The risk of transmitting hepatitis B virus from donors who are positive for hepatitis B core antibody but negative for hepatitis B surface antigen has been a major concern in liver transplantation. In the Kingdom of Saudi Arabia the overall prevalence of hepatitis B core antibody among the general population was reported to be very high indeed. The purpose of this study is to establish the prevalence of hepatitis B core antibody positivity among liver donors who are negative for hepatitis B surface antigen and offered for liver transplantation in the Kingdom of Saudi Arabia. METHODS: Hepatitis B serological …
Human Parvovirus B19 Infection Among Patients With Chronic Blood Disorders, Mona A. Badr
Human Parvovirus B19 Infection Among Patients With Chronic Blood Disorders, Mona A. Badr
Saudi Medical Journal
OBJECTIVE: In a normal host, parvovirus infection can be asymptomatic or can result in erythema infectiosum or arthropathy. Patients with underlying hematologic and immunologic disorders who become infected with this virus are at risk for aplastic anemia. This small study attempts to confirm this relation between the human parvovirus B19 infection as one of the predisposing factor of aplastic crisis in patients with hemolytic disorders. METHODS: The laboratory records of 73 patients9 serum samples, which were tested for detection of specific Immunoglobulin M and Immunoglobulin G antibody by means of the recurrently available indirect enzyme linked Immunoassay during the period …
Treatment Of Patients With Chronic Hepatitis C With Normal Liver Enzymes, Hisham O. Akbar
Treatment Of Patients With Chronic Hepatitis C With Normal Liver Enzymes, Hisham O. Akbar
Saudi Medical Journal
OBJECTIVE: This is a controlled prospective study to evaluate the efficacy of induction combination therapy using alpha-interferon and ribavirin in patients with chronic hepatitis C and persistently normal liver enzymes. METHODS: Forty-six patients with compensated liver disease tested positive for hepatitis C virus antibody between October 1998 and August 2000 at King Abdulaziz University Hospital and Al-Badriyah Towers, Jeddah Clinics, Jeddah, Kingdom of Saudi Arabia. Twelve patients had persistently normal liver enzymes for 6 months and 34 patients with abnormal liver enzymes (control). Patients were treated using induction combination therapy. Viral load response was measured using branched deoxyribonucleic acid signal …
Colorectal Cancers In Saudi Arabia, Ibrahim Mansoor, Ibrahim H. Zahrani, Syed Abdulaziz
Colorectal Cancers In Saudi Arabia, Ibrahim Mansoor, Ibrahim H. Zahrani, Syed Abdulaziz
Saudi Medical Journal
OBJECTIVE: The aim of this retrospective study is to delineate the histopathological profile of colorectal cancers seen at King AbdulAziz University Hospital, Jeddah, Kingdom of Saudi Arabia and to compare our findings with 12 other studies published in the literature from other areas of the Kingdom of Saudi Arabia. METHODS: Our study group consisted of 39 colorectal cancer patients, who were examined in the department of Histopathology at King AbdulAziz University Hospital, Jeddah, Kingdom of Saudi Arabia, over a period of 4 years from January 1996 to December 2000. The data was retrieved and analyzed. The histopathological characteristics of the …
Splenic Abscess In Childhood B-Thalassemia Major, Zakaria M. Al-Hawsawi, Tariq I. Hummaida
Splenic Abscess In Childhood B-Thalassemia Major, Zakaria M. Al-Hawsawi, Tariq I. Hummaida
Saudi Medical Journal
Splenic abscess is a rare complication of thalassemia major. In this paper we report a 10-year-old male thalassemic child with splenic abscess. He presented with high-grade fever, abdominal pain and tender splenomegaly. The diagnosis was confirmed by ultrasonography and computerized tomography scan of the abdomen. The patient underwent emergency splenectomy.
Etiology Of Pleural Effusion In Western Saudi Arabia, Faiza A. Qari
Etiology Of Pleural Effusion In Western Saudi Arabia, Faiza A. Qari
Saudi Medical Journal
No abstract provided.
Conduct Disorders In Childhood And Adolescence, Saleh Al-Jamal
Conduct Disorders In Childhood And Adolescence, Saleh Al-Jamal
Saudi Medical Journal
No abstract provided.
Nutritional Rickets And Osteomalacia In School Children And Adolescents, Nasir A. Al-Jurayyan, Mahmoud E. El-Desouki, Abdullah S. Al-Herbish, Abdullah S. Al-Mazyad, Maha M. Al-Qhtani
Nutritional Rickets And Osteomalacia In School Children And Adolescents, Nasir A. Al-Jurayyan, Mahmoud E. El-Desouki, Abdullah S. Al-Herbish, Abdullah S. Al-Mazyad, Maha M. Al-Qhtani
Saudi Medical Journal
OBJECTIVE: To review experiences of nutritional rickets and osteomalacia in school children and adolescents at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia. METHODS: Records of children and adolescents aged 6-18 years, seen at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia, during the period January 1994 through to December 1999, who were diagnosed to have rickets or osteomalacia were reviewed. The diagnosis was based on clinical, biochemical and radiological data. Data extracted and analyzed included age, sex, presenting symptoms and signs, dietary history and sun exposure, blood count, bone profiles, renal and liver profile, and 25-hydroxy vitamin …
Detection Of Extended-Spectrum B-Lactamases In Members Of The Family Enterobacteriaceae At A Teaching Hospital, Riyadh, Kingdom Of Saudi Arabia, Hanan A. Babay
Detection Of Extended-Spectrum B-Lactamases In Members Of The Family Enterobacteriaceae At A Teaching Hospital, Riyadh, Kingdom Of Saudi Arabia, Hanan A. Babay
Saudi Medical Journal
OBJECTIVE: To determine the prevalence of extended spectrum b-lactamase at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia and to compare the ability of the disc diffusion, double disc potentiation methods and the extended-spectrum b-lactamase E test to detect exended-spectrum b-lactamase among enterobacteriaceae. METHODS: This study was undertaken during the time period period January 1 through to September 30 1999, at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia. A total of 187 multiresistant isolates of enterobacteriacae from different clinical specimens were tested for the extended-spectrum b-lactamases. The performance of disc diffusion, double disc potentiation methods using cefotaxime, …
Cerebellar Abscess Due To Listeria Monocytogenes, Bassam M. Addas, Mohammed S. Jan
Cerebellar Abscess Due To Listeria Monocytogenes, Bassam M. Addas, Mohammed S. Jan
Saudi Medical Journal
Brain abscess due to listeria monocytogenes mainly involves the cerebral hemispheres. Cerebellar abscess is an infrequent event, which could lead to rapid neurological deterioration if unrecognized. We present a case of multiple brain stem and cerebellar abscesses in a previously healthy individual exposed to unpasteurized milk. This is the 2nd case of cerebellar abscess due to listeria monocytogenes reported in the English literature. The diagnosis of listeria monocytogenes was made in the surgical specimen. Our case illustrates the difficulty of early diagnosis of cerebellar listeria monocytogenes abscesses and the importance of prompt neurosurgical intervention.
Infundibular Buckling As An Adjunctive Sign Of Pituitary Adenoma, Bassam M. Addas, Mohammed M. Jan
Infundibular Buckling As An Adjunctive Sign Of Pituitary Adenoma, Bassam M. Addas, Mohammed M. Jan
Saudi Medical Journal
No abstract provided.
Tissue Factor. Biological Function And Clinical Significance, Bashir A. Lwaleed
Tissue Factor. Biological Function And Clinical Significance, Bashir A. Lwaleed
Saudi Medical Journal
Tissue Factor is the principal cellular initiator of normal blood coagulation. It is frequently encrypted in the plasma membrane of cells in contact with blood, but under certain pathological conditions endothelial cells, monocytes or macrophages may express tissue factor; and hence trigger coagulation activation. Aberrant expression of tissue factor by these cells is thought to be responsible for the thrombophilia found in septic shock, atherosclerosis and cancer. Tissue factor is produced by tumor-associated macrophages where it is believed to play an important role in tumor growth and dissemination. It may also be involved in other cellular processes such as intracellular …
Management Of Oral Cancer In A Tertiary Care Hospital, Saeed A. Al-Balawi, Alagumba L. Nwoku
Management Of Oral Cancer In A Tertiary Care Hospital, Saeed A. Al-Balawi, Alagumba L. Nwoku
Saudi Medical Journal
OBJECTIVE: Oral cancer is the 3rd most common cause of malignancy in Saudi Arabia after lymphoma and leukemia. The high incidence of oral cancer in this region is attributed to frequent use of tobacco (Shamma). In this report we have reviewed the mode of treatment and subsequent outcome of 228 oral cancer patients at the Oral Maxillofacial Surgery Unit of the Armed Forces Hospital, Riyadh, Kingdom of Saudi Arabia. METHODS: In this retrospective study the case notes of 228 oral cancer patients treated at the Armed Forces Hospital, Riyadh were reviewed. Age, sex, presenting symptoms, location of cancer in oral …
The Diagnosis Of Gastroesophageal Reflux Disease In Children, Asaad M. Abdullah
The Diagnosis Of Gastroesophageal Reflux Disease In Children, Asaad M. Abdullah
Saudi Medical Journal
OBJECTIVE: Gastroesophageal reflux disease is a common disorder affecting children worldwide. The objective of this study is to report our experience on the accuracy of tests used for the diagnosis ofgastroesophageal reflux disease with emphasis on the advantages and disadvantages of each of them. METHODS: This study took place in the Pediatric Gastroenterology Division, Department of Pediatrics, College of Medicine and King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia, during the period of 1994 through to 1999. Results of barium meal, 24-hour esophageal pH monitoring, endoscopy, and gastrointestinal scintigraphy are analyzed and compared in children with and without gastroesophageal …
Audit Of Referral Of Diabetic Patients, Yahia M. Al-Khaldi, Mohammed Y. Khan, Samir H. Khairallah
Audit Of Referral Of Diabetic Patients, Yahia M. Al-Khaldi, Mohammed Y. Khan, Samir H. Khairallah
Saudi Medical Journal
OBJECTIVE: To determine the referral, the feedback rates and to find out the prevalence of diabetic retinopathy among diabetics who were referred from a primary health care center, to Abha General Hospital in Aseer Region. METHODS: This study was conducted at Wasat Abha Primary Health Care Center in Aseer region at the end of 1996 and 1997. All the diabetic files were reviewed and evaluated for referral to the eye clinic, their feedback and the prevalence of diabetic retinopathy among diabetics for whom fundoscopy was carried out. The related data was entered and analyzed by using the statistical package for …
Bone Marrow Examination. Indications And Diagnostic Value, Layla A. Bashawri
Bone Marrow Examination. Indications And Diagnostic Value, Layla A. Bashawri
Saudi Medical Journal
OBJECTIVE: To identify the main indications for bone marrow examination in a University hospital setup and the most common diagnoses encountered. To also identify the extent of correlation, if any, between the preliminary diagnosis and the result of the final bone marrow diagnosis. METHODS: The requests and reports of all bone marrow biopsies and aspirations carried out during a 12-year period from January 1988 through to December 1999, in King Fahd Hospital of the University, Al Khobar, Kingdom of Saudi Arabia were retrospectively reviewed. The information extracted included the main indications for performing this procedure, age groups involved, and the …
Variations In The Subclavian-Axillary Arterial System, Muhammad Saeed, Amin A. Rufai, Salah E. Elsayed, Muhammad S. Sadiq
Variations In The Subclavian-Axillary Arterial System, Muhammad Saeed, Amin A. Rufai, Salah E. Elsayed, Muhammad S. Sadiq
Saudi Medical Journal
OBJECTIVE: The objective of this study is to report on the subclavian axillary arterial system variations observed in the dissecting room. METHODS: The morphological study of 106 formalin fixed upper limbs of adult human cadavers of both sexes was carried out at human anatomy laboratory of College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia over a 5 year period, to observe the distribution pattern of the subclavian axillary arterial system. RESULTS: The arterial variations in the upper extremities are quite common and may occur at the level of the thoracic outlet, axilla, arm, cubital fossa and the …
Zinc In Normal And Pathological Human Prostate Gland, Ziad M. Bataineh, Jamil R. Al-Alami
Zinc In Normal And Pathological Human Prostate Gland, Ziad M. Bataineh, Jamil R. Al-Alami
Saudi Medical Journal
OBJECTIVE: This study is conducted to detect quantitatively zinc in the nuclei and cytoplasm of epithelial cells of the prostate from normal, acute prostatitis, benign prostatic hyperplasia and adenocarcinoma. METHODS: Prostatic tissues from normal, acute prostatitis, benign prostatic hyperplasia and adenocarcinoma were obtained from patients and processed for zinc detection using x-ray microanalysis technique. The samples were collected over a period of 2-3 years and were processed at Jordan University of Science and Technology, Irbid, Jordan. RESULTS: Zinc was increased and decreased both in the nuclei and the cytoplasm of the glandular epithelium of benign prostatic hyperplasia and adenocarcinoma of …
Toxic Effect Of Tannic And Related Compounds On Human Plasma Proteins, Sabah M. Al-Shafi
Toxic Effect Of Tannic And Related Compounds On Human Plasma Proteins, Sabah M. Al-Shafi
Saudi Medical Journal
OBJECTIVE: To investigate the toxicity of tannic acid related compounds such as gallic acid and polyphenol on the activity of plasma proteins in vitro. Their electrophoretic results show extremely important information, albumin and globulin levels are remarkably changed and characterized by disorder in their fractions avere which occurred frequently. METHODS: All plasma proteins samples of sets A, B and C were treated in sequences with known different concentrations of gallic acid, gallotannin and polypholes, which were separated chromatographically from phenolic extract of fruit peel of punicaceae. These were then treated, A, B and C were subjected to electrophoresis techniques, for …
Myofibroblastoma Of The Breast In An Adolescent, Faisal M. Alam, Dushyanti S. Samarasinghe, Rajasekharan G. Pillai.
Myofibroblastoma Of The Breast In An Adolescent, Faisal M. Alam, Dushyanti S. Samarasinghe, Rajasekharan G. Pillai.
Saudi Medical Journal
A case of myofibroblastoma of the breast was recently diagnosed in an adolescent Omani boy. In this report, the clinical, histopathological and the radiological features of this rare disease are being discussed. We conclude that, myofibroblastoma of the breast, which was earlier described, predominantly, in elderlies, can occur in people from any age group.
Difficulties In Diagnosing Neuroleptic Malignant Syndrome, Monica S. Zolezzi, Abdullah M. Al-Hathloul
Difficulties In Diagnosing Neuroleptic Malignant Syndrome, Monica S. Zolezzi, Abdullah M. Al-Hathloul
Saudi Medical Journal
This report describes a recent case of neuroleptic malignant syndrome, a rare adverse effect of antipsychotic medications. Assessment of the neuroleptic malignant syndrome was carried out by using the Naranjo Algorithm Probability Scale which resulted in a highly probable reaction to haloperidol. The difficulties in establishing the diagnosis in this patient lead to late intervention resulting in a slow recovery and prolonged hospitalization. Our objective in this presentation is to highlight the importance of early recognition of this potentially fatal adverse drug reaction.
Delayed Presentation Of Bilateral Morgagni's Hernia In A Child With Down's Syndrome, Ahmed H. Al-Salem, Hussan A. Khawaher
Delayed Presentation Of Bilateral Morgagni's Hernia In A Child With Down's Syndrome, Ahmed H. Al-Salem, Hussan A. Khawaher
Saudi Medical Journal
This case report describes the delayed presentation of bilateral Morgagni9s hernia in a 13-month-old girl with Down9s Syndrome. The report emphasizes the fact that a previously normal chest x-ray should not preclude the diagnosis of Morgagni9s hernia even when bilateral. The various presentations and the association between Morgagni9s hernia and Down9s Syndrome are also discussed.
Post Tonsillectomy Quinsy, Sami Al-Kindy