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Insulin Resistance In China., Rinaldo Pellicano, Sharmila Fagoonee Jun 2011

Insulin Resistance In China., Rinaldo Pellicano, Sharmila Fagoonee

Saudi Medical Journal

No abstract provided.


Expression Of Transforming Growth Factor-Beta 1 And Connective Tissue Growth Factor In Women With Pelvic Organ Prolapse., Xiao-Ying Qi, Li Hong, Feng-Qin Guo, Qiong Fu, Lu Chen, Bing-Shu Li May 2011

Expression Of Transforming Growth Factor-Beta 1 And Connective Tissue Growth Factor In Women With Pelvic Organ Prolapse., Xiao-Ying Qi, Li Hong, Feng-Qin Guo, Qiong Fu, Lu Chen, Bing-Shu Li

Saudi Medical Journal

OBJECTIVES: To investigate the presence of transforming growth factor-beta 1 (TGF-ß1) and connective tissue growth factor (CTGF) in women with pelvic organ prolapse (POP). METHODS: This study was conducted from May to December 2009. Fifty patients with POP that underwent vaginal hysterectomy in the Department of Gynecology, Renmin Hospital of Wuhan University, Hubei, Wuhan, China were enrolled in this study. They were divided into: Group 1 (n=10); Group 2 (n=10); and Group 3 (n=10) according to Pelvic Organ Prolapse Quantitation (POP-Q). Meanwhile, 20 cases treated by vaginal hysterectomy for other benign gynecological diseases were selected as the control group. Immunohistochemical …


Prevalence Of Igg Antibodies Against Toxoplasma Gondii Among Syrian Females Of Childbearing Age., Faraj A. Barah May 2011

Prevalence Of Igg Antibodies Against Toxoplasma Gondii Among Syrian Females Of Childbearing Age., Faraj A. Barah

Saudi Medical Journal

No abstract provided.


Medical Students' Knowledge Of Ionizing Radiation And Radiation Protection., Sarah K. Hagi, Mawya A. Khafaji May 2011

Medical Students' Knowledge Of Ionizing Radiation And Radiation Protection., Sarah K. Hagi, Mawya A. Khafaji

Saudi Medical Journal

OBJECTIVES: To assess the knowledge of fourth-year medical students in ionizing radiation, and to study the effect of a 3-hour lecture in correcting their misconceptions. METHODS: A cohort study was conducted on fourth-year medical students at King Abdul-Aziz University, Jeddah, Kingdom of Saudi Arabia during the academic year 2009-2010. A 7-question multiple choice test-type questionnaire administered before, and after a 3-hour didactic lecture was used to assess their knowledge. The data was collected from December 2009 to February 2010. The lecture was given to 333 (72%) participants, out of the total of 459 fourth-year medical students. It covered topics in …


Acute Life Threatening Events Associated With Hypocalcemia And Vitamin D Deficiency In Early Infancy. A Single Center Experience From The Kingdom Of Saudi Arabia., Rafat M. Mosalli, Yasser Y. Elsayed, Bosco A. Paes May 2011

Acute Life Threatening Events Associated With Hypocalcemia And Vitamin D Deficiency In Early Infancy. A Single Center Experience From The Kingdom Of Saudi Arabia., Rafat M. Mosalli, Yasser Y. Elsayed, Bosco A. Paes

Saudi Medical Journal

No abstract provided.


Medication Administration Errors In Eastern Saudi Arabia., Mahmood D. Al-Mendalawi May 2011

Medication Administration Errors In Eastern Saudi Arabia., Mahmood D. Al-Mendalawi

Saudi Medical Journal

No abstract provided.


Castleman's Disease. Update On Pathogenesis., Jaudah A. Al-Maghrabi May 2011

Castleman's Disease. Update On Pathogenesis., Jaudah A. Al-Maghrabi

Saudi Medical Journal

Castleman9s disease (CD) is an unusual lymphoproliferative disorder that may mimic lymphoma clinically and pathologically. It is classified clinically as localized and multicentric types, and pathologically as hyaline vascular and plasma cell types. It is associated with increased risk of lymphoma and follicular dendritic cell tumors. The pathogenesis of CD is still controversial and complex. Active research is ongoing to highlight more on the etiopathogenesis of this entity. The aim of this article is to review the literature on pathogenesis of CD and to focus on the possible role of viruses in the development of this disease.


L-Arginine-Glycine Amidinotransferase, Betaine-Homocysteine S-Methyltransferase, And Neuropolypeptide H3 Are Diminished In Renal Clear Cell Carcinoma Of Humans., Jian-Ping Peng, Jie Zhang, Hsuan-Wei Huang, Feng-Hua Wang, Xian-Jin Du, Peng-Cheng Luo May 2011

L-Arginine-Glycine Amidinotransferase, Betaine-Homocysteine S-Methyltransferase, And Neuropolypeptide H3 Are Diminished In Renal Clear Cell Carcinoma Of Humans., Jian-Ping Peng, Jie Zhang, Hsuan-Wei Huang, Feng-Hua Wang, Xian-Jin Du, Peng-Cheng Luo

Saudi Medical Journal

OBJECTIVES: To identify renal clear cell carcinoma-associated marker proteins. METHODS: Twelve patients with renal cell carcinoma (RCC) were collected and processed in the Department of Urology, Renmin Hospital, Wuhan University, China, between January 2008 and September 2009. Two-dimensional polyacrylamide gel electrophoresis and matrix assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF-MS) were employed to investigate differentially expressed protein spots between RCC tissues and adjacent normal tissues, then reverse transcription polymerase chain reaction and western blot were employed to confirm the proteomic results. RESULTS: One protein spot was upregulated, 13 were downregulated, and 22 were absent in RCC tissues. Four of …


Drug Susceptibility Pattern Of Mycobacterium Tuberculosis Isolates Against Conventional Anti-Tuberculosis Drugs In Dhaka, Bangladesh., Abdul Mottalib, Murad Hossain, Ibrahim Khalil, Sirazul Islam, Anwar Hossain May 2011

Drug Susceptibility Pattern Of Mycobacterium Tuberculosis Isolates Against Conventional Anti-Tuberculosis Drugs In Dhaka, Bangladesh., Abdul Mottalib, Murad Hossain, Ibrahim Khalil, Sirazul Islam, Anwar Hossain

Saudi Medical Journal

OBJECTIVES: To investigate the drug susceptibility pattern of isolated Mycobacterium tuberculosis (M. tuberculosis) against conventional anti-tuberculosis drugs in Dhaka, Bangladesh. METHODS: Sputum samples from 101 suspected new and previously treated patients were collected and M. tuberculosis was identified by microscopic observation and Ziehl-Neelsen staining. Drug susceptibility was performed against 4 anti-tuberculosis drugs, and the obtained data was analyzed. This study was performed in the Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders Hospital, Dhaka, Bangladesh between October 2008 and November 2009. RESULTS: Among 101 suspected, 59 (58.4%) cases were identified as M. tuberculosis and the drug …


Device-Associated Infection Rates And Bacterial Resistance In The Intensive Care Units Of A Turkish Referral Hospital., Emin E. Tutuncu, Yunus Gurbuz, Irfan Sencan, Baris Ozturk, Gonul C. Senturk, Aysegul U. Kilic May 2011

Device-Associated Infection Rates And Bacterial Resistance In The Intensive Care Units Of A Turkish Referral Hospital., Emin E. Tutuncu, Yunus Gurbuz, Irfan Sencan, Baris Ozturk, Gonul C. Senturk, Aysegul U. Kilic

Saudi Medical Journal

OBJECTIVES: To determine device-associated infection (DAI) rates, and the microbiological and antibiotic resistance profiles of infecting pathogens in our hospital. METHODS: Prospective surveillance of healthcare-associated infections was performed from January 2007 to March 2010 in 4 different intensive care units (ICUs) of SB Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey. RESULTS: During the study period, 6,005 patients were followed-up in ICUs for a total of 46,355 patient-days. The total number of DAIs was 969. Catheter-associated urinary tract infection (CAUTI) was the most common DAI (55.3% of DAIs; 11.9 cases per 1000 catheter-days), followed by ventilator-associated pneumonia (VAP) (38.9% …


Vitamin A Status In Wheezing Saudi Children., Sherein A. Shalaby, Khaild M. Al-Harbi, Shereen A. El-Tarhouny May 2011

Vitamin A Status In Wheezing Saudi Children., Sherein A. Shalaby, Khaild M. Al-Harbi, Shereen A. El-Tarhouny

Saudi Medical Journal

OBJECTIVES: To examine the serum retinol levels of wheezing children, and to investigate the relation as an biochemical indicator of vitamin A status in wheezing children between serum levels of retinol and severity of wheezing. METHODS: A prospective cohort study including 400 wheezing Saudi children aged 3-36 months, who were treated in the pediatrics ward of Ohoud Public Hospital in Al-Madinah, Kingdom of Saudi Arabia between January 2009 and August 2010. Patients were subdivided according to the course of wheeze into 93 patients with persistent wheeze, and 307 patients with acute wheeze. Severity of wheeze was graded mild, moderate, and …


Hand Hygiene Compliance Rate Among Healthcare Professionals., Syed Z. Bukhari, Waleed M. Hussain, Abdulhakeem Banjar, Wail H. Almaimani, Talal M. Karima, Mohammad I. Fatani May 2011

Hand Hygiene Compliance Rate Among Healthcare Professionals., Syed Z. Bukhari, Waleed M. Hussain, Abdulhakeem Banjar, Wail H. Almaimani, Talal M. Karima, Mohammad I. Fatani

Saudi Medical Journal

OBJECTIVES: To motivate healthcare professionals, with a focus on improving hand hygiene compliance. METHODS: An observational, prospective, longitudinal study was conducted on the evaluation of hand hygiene compliance at Hera General Hospital, Makkah, Kingdom of Saudi Arabia from May 2009 to May 2010. Four components to improve hand hygiene compliance were implied; daily audit, monthly staff education; quarterly workshops of hand hygiene, and education material distribution. The compliance rate was calculated by its adherence with number of opportunities. RESULTS: Of total 163 healthcare professionals were surveyed for hand hygiene compliance; 57 (35%) were doctors, 92 (56.4%) nurses, and 14 (8.6%) …


The Effect Of Nurse-Patient Language Barrier On Patients' Satisfaction., Mahmood D. Al-Mendalawi May 2011

The Effect Of Nurse-Patient Language Barrier On Patients' Satisfaction., Mahmood D. Al-Mendalawi

Saudi Medical Journal

No abstract provided.


Pilot-Randomized Study On Intraventricular Hemorrhage With Midline Versus Lateral Head Positions, Sameer Y. Al-Abdi, Maha S. Nojoom, Hesham M. Alshaalan, Maryam Ali Al-Aamri Apr 2011

Pilot-Randomized Study On Intraventricular Hemorrhage With Midline Versus Lateral Head Positions, Sameer Y. Al-Abdi, Maha S. Nojoom, Hesham M. Alshaalan, Maryam Ali Al-Aamri

Saudi Medical Journal

No abstract provided.


Cyp2c9 Polymorphism Studies In The Saudi Population, Jalal N. Saour, Atia W. Shereen, Basil J. Saour, Layla A. Mammo Apr 2011

Cyp2c9 Polymorphism Studies In The Saudi Population, Jalal N. Saour, Atia W. Shereen, Basil J. Saour, Layla A. Mammo

Saudi Medical Journal

OBJECTIVE: To determine the prevalence of CYP2C9 polymorphism in normal Saudis (controls), in Saudi patients with venous thrombosis, in patients requiring low dose warfarin (study group) for anticoagulation, and to compare our results to those from other populations. METHODS: Blood from the control and study groups was collected from November 2001 to November 2008. The DNA was extracted, stored at -700C and later tested for the CYP2C9 polymorphism using established methods. Clinical data were collected through direct interview, chart review, and the Saudi Thrombosis and Familial Thrombophilia Registry. All individuals consented. RESULTS: The prevalence of CYP2C9 polymorphisms in the Saudi …


New And Known Mutations Associated With Inborn Errors Of Metabolism In A Heterogeneous Middle Eastern Population, Bassam R. Ali, Jozef L. Hertecant, Fatima A. Al-Jasmi, Mohamed A. Hamdan, Sawsan F. Khuri, Nadia A. Akawi, Lihadh I. Al-Gazali Apr 2011

New And Known Mutations Associated With Inborn Errors Of Metabolism In A Heterogeneous Middle Eastern Population, Bassam R. Ali, Jozef L. Hertecant, Fatima A. Al-Jasmi, Mohamed A. Hamdan, Sawsan F. Khuri, Nadia A. Akawi, Lihadh I. Al-Gazali

Saudi Medical Journal

OBJECTIVE: To identify the mutations underlying a number of inborn errors of metabolism (IEM) disorders among United Arab Emirates (UAE) residents. METHODS: Molecular diagnostic and bioinformatics tools were used to identify the causative mutations of IEM disorders from multi-ethnic patients residing in UAE. The study was conducted in Al-Ain, UAE, between April 2009 and September 2010. This is a case series retrospective study where patients attending the metabolic clinic at Tawam Hospital were recruited. Thirty patients and 26 parents were included. RESULTS: We present evidence in the UAE of 7 new mutations and 19 mutations that have previously been reported …


Effect Of Combination Of Edible Oils On Blood Pressure, Lipid Profile, Lipid Peroxidative Markers, Antioxidant Status, And Electrolytes In Patients With Hypertension On Nifedipine Treatment, Balasubramanian Sudhakar, Panneerselvam Kalaiarasi, Khalid S. Al-Numair, Govindasamy Chandramohan, Rama K. Rao, Kodukkur V. Pugalendi Apr 2011

Effect Of Combination Of Edible Oils On Blood Pressure, Lipid Profile, Lipid Peroxidative Markers, Antioxidant Status, And Electrolytes In Patients With Hypertension On Nifedipine Treatment, Balasubramanian Sudhakar, Panneerselvam Kalaiarasi, Khalid S. Al-Numair, Govindasamy Chandramohan, Rama K. Rao, Kodukkur V. Pugalendi

Saudi Medical Journal

OBJECTIVE: To determine the effect of combination of edible oils on blood pressure, anthropometric parameters, lipid profile, lipid peroxidative markers, antioxidant status and electrolytes in drug (nifedipine) taking patients with hypertension. METHODS: In this study, patients were separated into 4 groups. Normal (n=14), hypertensive patients (n=38), 38 patients under medication with nifedipine were divided into 2 groups nifedipine control (n=12) and nifedipine + oil combination (sesame + sunflower oil) groups (n=26). Sesame and sunflower oil combination was supplied to patients and instructed to use it as the only oil source for 45 days. Blood pressure and anthropometric parameters were measured …


Rapid Detection And E-Test Antimicrobial Susceptibility Testing Of Vibrio Parahaemolyticus Isolated From Seafood And Environmental Sources In Malaysia, Saleh M. Al-Othrubi, Alfizah Hanafiah, Son Radu, Humin Neoh, Rahaman Jamal Apr 2011

Rapid Detection And E-Test Antimicrobial Susceptibility Testing Of Vibrio Parahaemolyticus Isolated From Seafood And Environmental Sources In Malaysia, Saleh M. Al-Othrubi, Alfizah Hanafiah, Son Radu, Humin Neoh, Rahaman Jamal

Saudi Medical Journal

OBJECTIVE: To find out the prevalence and antimicrobial susceptibility of Vibrio parahaemolyticus in seafoods and environmental sources. METHODS: The study was carried out at the Center of Excellence for Food Safety Research, University Putra Malaysia; Universiti Kebangsaan Malaysia; Medical Molecular Biology Institute; and University Kebansaan Malaysia Hospital, Malaysia between January 2006 and August 2008. One hundred and forty-four isolates from 400 samples of seafood (122 isolates) and seawater sources (22 isolates) were investigated for the presence of thermostable direct hemolysin (tdh+) and TDH-related hemolysin (trh+) genes using the standard methods. The E-test method was used to test the antimicrobial susceptibility. …


Bacillus Calmette-Guerins Vaccination At Birth Causing Tuberculous Granulomatous Lymphadenitis, Abdulaziz A. Al-Hassan, Abumusa M. Ahsanullah Apr 2011

Bacillus Calmette-Guerins Vaccination At Birth Causing Tuberculous Granulomatous Lymphadenitis, Abdulaziz A. Al-Hassan, Abumusa M. Ahsanullah

Saudi Medical Journal

A rare but severe complication of Bacillus Calmette-Guerin (BCG) vaccination is the development of BCG disease, which can result in necrotizing granulomatous lymphadenitis. Symptoms can present as late as several months following the BCG vaccination. The key finding in BCG disease is the formation of caseating granulomas in draining lymph nodes; detection of BCG organisms from tissue samples are evident.


Association Of Cell Blood Counts And Cardiometabolic Risk Factors Among Young Obese Children, Mahmood D. Al-Mendalawi, Roya Kelishadi Apr 2011

Association Of Cell Blood Counts And Cardiometabolic Risk Factors Among Young Obese Children, Mahmood D. Al-Mendalawi, Roya Kelishadi

Saudi Medical Journal

No abstract provided.


Study Of Some Salivary Changes In Cutaneous Psoriatic Patients, Rania A. Soudan, Saleh A. Daoud, Ammar M. Mashlah Apr 2011

Study Of Some Salivary Changes In Cutaneous Psoriatic Patients, Rania A. Soudan, Saleh A. Daoud, Ammar M. Mashlah

Saudi Medical Journal

OBJECTIVE: To assess any alteration in the levels of some salivary components, and to correlate the same with the severity of the disease. METHODS: Unstimulated whole saliva samples were collected and analyzed in 20 randomly selected Syrian uncomplicated psoriatic patients presenting to the Dermatological Diseases Hospital, Damascus University, Syria between February and June 2010, and in 20 healthy matched controls. Sodium (Na+), potassium (K+), chloride (Cl-), and alpha amylase (sAA) was analyzed. The salivary flow rates (SFR) and pH was also studied. The Psoriasis Area and Severity Index was used to assess the severity of the disease. Student t-test and …


General Health Improves With Home-Based Cardiac Rehabilitation Program, Sarieh Poortaghi, Shirin B. Atri, Abdolrasoul Safayian, Ali Baghernia Apr 2011

General Health Improves With Home-Based Cardiac Rehabilitation Program, Sarieh Poortaghi, Shirin B. Atri, Abdolrasoul Safayian, Ali Baghernia

Saudi Medical Journal

OBJECTIVE: To determine whether continuing cardiac rehabilitation programs at home has positive effects on psychological and general health of the participants9 in comparison with the control group. METHODS: This randomized controlled trial was conducted in Tabriz Shahid Madani rehabilitation center, Tabriz, Iran between February 2009 and January 2010. Eighty patients referred to the rehabilitation center were randomly divided into case and control groups. Both groups received routine cardiac rehabilitation program in the rehabilitation center. In addition, the case group received education and practical training in various rehabilitation measures along with home visits of a community health nurse in follow-up period. …


An Elderly Man With Fibrotic Lung Disease, Sultan T. Al-Otaibi, Thamer H. Al-Khouzaie Apr 2011

An Elderly Man With Fibrotic Lung Disease, Sultan T. Al-Otaibi, Thamer H. Al-Khouzaie

Saudi Medical Journal

No abstract provided.


Accident Reconstruction Of Some Uncommon Spinal Injuries In Auto-Crashes In The Kingdom Of Saudi Arabia, Naif K. Al-Shammari, Ahamedali A. Hassan, Clive N. Sturgess, Ali S. Al-Mejrad Apr 2011

Accident Reconstruction Of Some Uncommon Spinal Injuries In Auto-Crashes In The Kingdom Of Saudi Arabia, Naif K. Al-Shammari, Ahamedali A. Hassan, Clive N. Sturgess, Ali S. Al-Mejrad

Saudi Medical Journal

No abstract provided.


Incidence Of Cleft Lip And Palate In Iran. A Meta-Analysis, Saber Khazaei, Amir Mansour Shirani, Mozafar Khazaei, Farid Najafi Apr 2011

Incidence Of Cleft Lip And Palate In Iran. A Meta-Analysis, Saber Khazaei, Amir Mansour Shirani, Mozafar Khazaei, Farid Najafi

Saudi Medical Journal

OBJECTIVE: To investigate meta-analysis of published data on overall incidence of cleft lip, cleft palate, and cleft lip and palate of newborns in Iran. METHODS: This meta-analysis was carried out at the School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran between May 2009 and December 2009. Our data were consisted of all incidences of cleft lip and palate from 1978 to June 2009, and we selected 11 studies. Inverse-variance weighting was implemented to calculate the random effect summary estimates and to produce a forest plot. Cumulative meta-analysis on published data was calculated and grouped. Publication bias was checked …


Rickets And Dysmorphic Findings In A Child With Abetalipoproteinemia, Mahmood D. Al-Mendalawi, Mohammed Y. Hasosah Apr 2011

Rickets And Dysmorphic Findings In A Child With Abetalipoproteinemia, Mahmood D. Al-Mendalawi, Mohammed Y. Hasosah

Saudi Medical Journal

No abstract provided.


Rotavirus Gastroenteritis And Strain Diversity In Saudi Arabia. Current Status And Future Prospects, Mahmood D. Al-Mendalawi Apr 2011

Rotavirus Gastroenteritis And Strain Diversity In Saudi Arabia. Current Status And Future Prospects, Mahmood D. Al-Mendalawi

Saudi Medical Journal

No abstract provided.


End Stage Chronic Kidney Disease In Saudi Arabia. A Rapidly Changing Scene, Abdulla A. Al-Sayyari, Faissal A. Shaheen Apr 2011

End Stage Chronic Kidney Disease In Saudi Arabia. A Rapidly Changing Scene, Abdulla A. Al-Sayyari, Faissal A. Shaheen

Saudi Medical Journal

There have been a marked rise in the prevalence and incidence of end stage chronic kidney disease (CKD) in Saudi Arabia over the last 3 decades. This rise exceeds those reported from many countries. The enormous and rapid changes in lifestyle, high population growth, and fast increase in life expectancy, and massive urbanization that has occurred over the last 3 decades combined to make the current CKD status different to what it was. The 2 major factors that influence the CKD status are the very high rate of diabetic nephropathy and shift in age demographics.


Hla-B27 And Its Subtypes In Syrian Patients With Ankylosing Spondylitis, Elham Ibrahim Harfouch, Salwa A. Al-Cheikh Apr 2011

Hla-B27 And Its Subtypes In Syrian Patients With Ankylosing Spondylitis, Elham Ibrahim Harfouch, Salwa A. Al-Cheikh

Saudi Medical Journal

OBJECTIVE: To assess HLA-B*27 and its subtypes associated with ankylosing spondylitis (AS) in Syrian patients. METHODS: A polymerase chain reaction with specific sequence primer method were used to study the HLA-B* locus polymorphism in 50 Syrian patients fulfilling the modified New York criteria for classification of ankylosing spondylitis and 217 unrelated healthy Syrian controls. Patients were recruited from the Outpatients Department, Alassad University Hospital, Damascus, Syria between December 2006 and December 2007. The study took place at the Laboratory for Research and Genetic Consultations, Faculty of Medicine, Damascus University, Damascus Syria. RESULTS: HLA-B*27 allele was found in 1.4% healthy Syrians …


Manipulation Of Flaxseed Inhibits Tumor Necrosis Factor-Alpha And Interleukin-6 Production In Ovarian-Induced Osteoporosis, Hala M. Abdelkarem, Seham A. Kasem Apr 2011

Manipulation Of Flaxseed Inhibits Tumor Necrosis Factor-Alpha And Interleukin-6 Production In Ovarian-Induced Osteoporosis, Hala M. Abdelkarem, Seham A. Kasem

Saudi Medical Journal

OBJECTIVE: To evaluate the potential effects of whole flaxseed (FS), and/or flax oil (FO) incorporation into the diet on the level of pro-inflammatory cytokines in ovariectomized (OVX) rats model of osteoporosis. METHODS: This study was performed in the Food Science & Agriculture Collage, King Saud University, Kingdom of Saudi Arabia from October to December 2009. Forty-eight, 3-month-old female Sprague-Dawley rats were randomly divided into 6 groups: Group 1 - sham + control diet; Group 2 - OVX rats + basal diet; Group 3 - OVX + 20% whole FS; Group 4 - OVX rats + 40% FS; Group 5 - …