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Estimating Autism Prevalence Among Children In The Kingdom Of Saudi Arabia: A Comprehensive Multisource Benchmarking Approach, Hadeel Khamees, Patrick Linnenbank, Ankita Gulati, Arindam Vatsa, Mohammed Aldosari, Ehsan Hoque
Estimating Autism Prevalence Among Children In The Kingdom Of Saudi Arabia: A Comprehensive Multisource Benchmarking Approach, Hadeel Khamees, Patrick Linnenbank, Ankita Gulati, Arindam Vatsa, Mohammed Aldosari, Ehsan Hoque
Saudi Medical Journal
ABSTRACT Objectives: To provide an accurate estimate of autism spectrum disorder (ASD) prevalence among children in the Kingdom of Saudi Arabia (KSA) by benchmarking against international and regional data, addressing the limitations of the currently reported prevalence rate of 0.6%. Methods: We conducted a comparative benchmarking analysis using ASD prevalence data from countries with advanced monitoring systems (United Kingdom, United States, Denmark, South Korea, Italy, Singapore) and regional comparators (United Arab Emirates, Qatar, Jordan). We assessed differences in healthcare infrastructure, diagnostic frameworks, and screening intensity, and reviewed recent KSA-based studies. Methodological limitations such as underreporting, cultural stigma, and diagnostic inconsistencies …
Comparative Analysis Of Autophagy And Apoptosis Pathways In Viral And Alcoholic Cirrhosis: An Immunohistochemical Study, Gunnur Demircan, Selimcan Berk, Doga Karayilan, Berkay T. Ozgur, Sema Ketenci, Ipek Elbegi, Vildan Karpuz, Melike Yavuz, Ahmet Midi, Demet Akin
Comparative Analysis Of Autophagy And Apoptosis Pathways In Viral And Alcoholic Cirrhosis: An Immunohistochemical Study, Gunnur Demircan, Selimcan Berk, Doga Karayilan, Berkay T. Ozgur, Sema Ketenci, Ipek Elbegi, Vildan Karpuz, Melike Yavuz, Ahmet Midi, Demet Akin
Saudi Medical Journal
Objectives: To study the different cellular death mechanisms between viral cirrhosis and alcoholic cirrhosis. The research investigated autophagy and apoptosis mechanisms in hepatitis B virus (HBV), hepatitis C virus (HCV) and alcohol-induced cirrhosis. Methods: The research team analyzed biopsy samples from the liver which were obtained at Florence Nightingale Hospitals, Istanbul, Turkey. The experimental protocols were performed between February 2021 and February 2023. The study included 19 HBV, 15 HCV, 13 alcohol-related cirrhosis patients and 6 normal liver tissues. Beclin-1, Caspase-3, Bcl-2 and LC3 expressions were evaluated by immunohistochemistry. Results: Staining intensity as well as extent underwent evaluation through H-score …
The Relationship Of St6gal1 With Clinicopathological And Prognostic Factors In Breast Carcinomas, Ethem Ömeroğlu, Abdülhalim Serden Ay, Tuğba Günler, İlknur Küçükosmanoğlu, Sümeyye Kozacıoğlu
The Relationship Of St6gal1 With Clinicopathological And Prognostic Factors In Breast Carcinomas, Ethem Ömeroğlu, Abdülhalim Serden Ay, Tuğba Günler, İlknur Küçükosmanoğlu, Sümeyye Kozacıoğlu
Saudi Medical Journal
Objectives: To investigate the association of β-galactoside α2-6 sialyltransferase 1 (ST6GAL1) expression with hormone receptor (HR), human epidermal growth factor receptor 2 (HER2), and other clinicopathological parameters, including histological grade, stage, lymphovascular invasion, perineural invasion, and survival in breast carcinomas (BCs). Methods: This study included 85 patients who had undergone surgery for breast cancer (BC). The associations of HR, HER2 status, and histopathologic tumor characteristics with immunohistochemical expression of ST6GAL1 were analyzed. Results: The majority (48 [56.5%]) of patients were in the T2 stage, and no association was seen between staging and ST6GAL1 ( p <0.05). Further, 44 (54.2%) patients were HR positive, and most of them exhibited high ST6GAL1 levels ( p =0.001), whereas 44 (51.8%) were HER2 negative, and most of them demonstrated low ST6GAL1 levels ( p =0.007). Ki-67 of ≥20% was observed in 55 (64.7%) and <20% in 30 (35.3%) patients. Most of those with high Ki-67 demonstrated low-grade STLGAL1 expression; however, no correlation was detected between the two values ( p =0.378). High and low ST6GAL1 expressions were observed in 39 (45.9%) and 46 (54.1%) cases, respectively. Conclusion: This research is one of the first studies to use ST6GAL1 in preoperative biopsies of patients not scheduled for neoadjuvant treatment. This study revealed highly significant associations of ST6GAL1 expression with HR, HER2, and molecular subtyping. Future studies are recommended to clarify the possible role of ST6GAL1 in resistance to HR and HER2-targeted and other chemotherapeutic agents in BCs.
Empowering Saudi Pharmacy Students: A Nudge-Based Intervention For Improved Health Behaviors, Fahad M. Alzahrani, Bsmah S. Bojan, Haifa A. Fadil
Empowering Saudi Pharmacy Students: A Nudge-Based Intervention For Improved Health Behaviors, Fahad M. Alzahrani, Bsmah S. Bojan, Haifa A. Fadil
Saudi Medical Journal
Objectives: To promote healthy habits among pharmacy students through curriculum-embedded challenges. Student well-being is a growing concern in Saudi pharmacy education, with high rates of stress and poor health behaviors reported among students. Traditional interventions often fall short in bridging the gap between awareness and action. Methods: A quasi-experimental design was conducted from September to December 2024 at Taibah University. Four month-long challenges targeting smartphone use, physical activity, sleep, and gratitude were integrated into a required hospital pharmacy course. The intervention was grounded in behavioral economics principles (salience and inertia) and delivered via Blackboard LMS with minimal extrinsic incentives. A …
Prognostic Significance Of The Borrmann Classification In Stage 2–3 Gastric Cancer, Selcan Cesur, Yonca Yılmaz Ürün
Prognostic Significance Of The Borrmann Classification In Stage 2–3 Gastric Cancer, Selcan Cesur, Yonca Yılmaz Ürün
Saudi Medical Journal
Objectives: To assess the prognostic significance of Borrmann classification subtypes in patients with stage 2–3 gastric cancer who underwent surgical treatment. Methods: A retrospective review of 96 gastric cancer patients treated at Van Yüzüncü Yıl University Medical Faculty Hospital from 2008 to 2024 was conducted. Patients were included if they were aged >18 year (yr), had undergone surgery without neoadjuvant therapy, had no distant metastases, and had a postoperative pathological stage of 2-3. Demographic and clinicopathological data were documented, and median overall survival (OS) was analyzed according to the Borrmann classification. Results: The median age of the 96 patients was …
The Incidence Of Unplanned Reoperation And The Related Risk Factors In Pediatric Surgery At A Tertiary Care Center In Saudi Arabia, Noura M. Almutairi, Mohammed K. Alnamshan, Suliman Mohammed Alaqeel
The Incidence Of Unplanned Reoperation And The Related Risk Factors In Pediatric Surgery At A Tertiary Care Center In Saudi Arabia, Noura M. Almutairi, Mohammed K. Alnamshan, Suliman Mohammed Alaqeel
Saudi Medical Journal
ABSTRACT Objectives: To evaluate unplanned reoperation (URO) as a quality indicator and identify its rate and associated risk factors at our institution. Parental satisfaction and patient safety are crucial, necessitating an investigation into the factors influencing unplanned return to the operating room rates. Understanding the reasons behind UROs and how to prevent them is vital for improving surgical services. Methods: This study employs a retrospective cohort design to analyze existing patient data from King Abdullah Specialized Children’s Hospital in Riyadh, Saudi Arabia. It aims to evaluate clinical endpoints and factors associated with unplanned reoperations, which are defined as any secondary …
Autism Spectrum Disorder In Saudi Arabia: Clinical Dynamics From A Multi-Center Study, Sulhi A. Alfakeh, Ghaida H. Aljahdali, Sarah T. Benfeef
Autism Spectrum Disorder In Saudi Arabia: Clinical Dynamics From A Multi-Center Study, Sulhi A. Alfakeh, Ghaida H. Aljahdali, Sarah T. Benfeef
Saudi Medical Journal
Objectives: Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by impairments in communication, social interaction, and behavior. This study aimed to explore the factors influencing the clinical presentation of children with ASD in Saudi Arabia, focusing on demographic, medical, and environmental determinants. Methods: A multi-center, cross-sectional study was conducted in Saudi Arabia, enrolling 104 children diagnosed with ASD. Data were collected via structured parent interviews and analyzed to examine the relationships between demographic characteristics, therapy participation, self-care abilities, and clinical symptoms. Results: Male children were more likely to exhibit hyperactivity compared to females ( p =0.037). Age was significantly …
Do Fitness Apps Do More Harm Than Good?
No Safe Level: Act Now To End Lead Exposure
No Safe Level: Act Now To End Lead Exposure
Saudi Medical Journal
No abstract provided.
Knowledge Of Hypoglycemia And Awareness Of Diabetes Complications Among Diabetic Patients: A Cross-Sectional Study, Eman A. Alshafei, Salhah S. Alsulami, Iman M. Wahby, Abdulrahman T. Abudawood, Taif T. Algaidy, Asma A. Alyoubi, Taif Y. Alyoubi, Arwa A. Alnoumani, Halah F. Alqurashi, Amal H. Alawdi
Knowledge Of Hypoglycemia And Awareness Of Diabetes Complications Among Diabetic Patients: A Cross-Sectional Study, Eman A. Alshafei, Salhah S. Alsulami, Iman M. Wahby, Abdulrahman T. Abudawood, Taif T. Algaidy, Asma A. Alyoubi, Taif Y. Alyoubi, Arwa A. Alnoumani, Halah F. Alqurashi, Amal H. Alawdi
Saudi Medical Journal
ABSTRACT Objectives: To assess awareness of diabetes complications and knowledge of hypoglycemia. Methods: This cross-sectional study was conducted in a tertiary hospital between December 2022 and November 2023. The participants were 362 adult patients with diabetes selected using systematic random sampling. Data were collected through structured interviews using a validated questionnaire that included sections on socio-demographic characteristics, diabetes history, and knowledge of hypoglycemia and awareness about diabetes complications. Descriptive statistics and one-way ANOVA were used for data analysis. Results: The majority of participants were female (71.3%), and 227 (62.7%) had been diabetic for more than 10 years. Approximately 37% are …
Saudi Clinical Practice Guidelines For Management Of Diabetic Kidney Disease In Adults, Khalid I. Almatham, Hajer Y. Almudaiheem, Waleed A. Alhazzani, Haifa F. Alotaibi, Saad S. Alobaili, Mohammed H. Tawhari, Saud N. Alsifri, Rehab B. Albakr, Mohammed N. Alomi, Khalidah A. Alenzi, Bedor A. Al-Omari, Ahmed H. Al-Jedai
Saudi Clinical Practice Guidelines For Management Of Diabetic Kidney Disease In Adults, Khalid I. Almatham, Hajer Y. Almudaiheem, Waleed A. Alhazzani, Haifa F. Alotaibi, Saad S. Alobaili, Mohammed H. Tawhari, Saud N. Alsifri, Rehab B. Albakr, Mohammed N. Alomi, Khalidah A. Alenzi, Bedor A. Al-Omari, Ahmed H. Al-Jedai
Saudi Medical Journal
ABSTRACT Objectives: To develop evidence-based national guidelines incorporating recent advancements in clinical research and therapeutic strategies for the management of patients with diabetic kidney disease (DKD) in the Kingdom of Saudi Arabia (KSA). Methods: We developed the guidelines using the GRADE methodology and a multidisciplinary expert panel comprising nephrologists, endocrinologists, clinical pharmacists, and methodologists across KSA. We conducted a systematic literature review of studies published between 2014–2024. The evidence certainty was evaluated across 5 domains using GRADEpro and categorized into 4 levels: “high”, “moderate”, “low”, and “very low”. Recommendations were formulated based on the benefit-risk ratio, evidence quality, and expert …
Are Patients Undergoing Surgery For Early-Stage Cancer At Risk Of Persistent Opioid Use?
Are Patients Undergoing Surgery For Early-Stage Cancer At Risk Of Persistent Opioid Use?
Saudi Medical Journal
No abstract provided.
Integrating Point-Of-Care Ultrasound Into Prehospital Care, Hatem Soliman Aboumarie
Integrating Point-Of-Care Ultrasound Into Prehospital Care, Hatem Soliman Aboumarie
Saudi Medical Journal
No abstract provided.
Breastfeeding In Indonesia On The Rise, But Mothers Need More Support
Breastfeeding In Indonesia On The Rise, But Mothers Need More Support
Saudi Medical Journal
No abstract provided.
Translating Evidence To Action To Improve Care And Outcomes In Type 2 Diabetes And Chronic Kidney Disease, Joshua J. Neumiller, Nuha A. Elsayed
Translating Evidence To Action To Improve Care And Outcomes In Type 2 Diabetes And Chronic Kidney Disease, Joshua J. Neumiller, Nuha A. Elsayed
Saudi Medical Journal
No abstract provided.
Approaches To Reduce The Impact Of Stroke In Gulf Cooperation Council Nations, Muath A. Alammar
Approaches To Reduce The Impact Of Stroke In Gulf Cooperation Council Nations, Muath A. Alammar
Saudi Medical Journal
No abstract provided.
The Economic Burden Of Atherosclerotic Cardiovascular Disease In The Kingdom Of Saudi Arabia, Mirvat Alasnag, Adel Tash
The Economic Burden Of Atherosclerotic Cardiovascular Disease In The Kingdom Of Saudi Arabia, Mirvat Alasnag, Adel Tash
Saudi Medical Journal
No abstract provided.
Phase Iv Clinical Trials For The Treatment Of Non-Small Cell Lung Carcinoma (Nsclc): A Systemic Review From 2020-2025, Yousif A. Kariri, Mohammed H. Alqasmi, Bijad S. Alqahtani
Phase Iv Clinical Trials For The Treatment Of Non-Small Cell Lung Carcinoma (Nsclc): A Systemic Review From 2020-2025, Yousif A. Kariri, Mohammed H. Alqasmi, Bijad S. Alqahtani
Saudi Medical Journal
ABSTRACT Objective: To evaluate and provide evidence on drugs investigated in completed phase IV clinical trials for adult non-small cell lung carcinoma (NSCLC) therapy, primarily focusing on treatment objectives and adverse effects. Methods: Clinical research studies from January 2020 to January 2025 were systematically reviewed using the “ClinicalTrials.gov” database. The inclusion criteria focused on publicly available, relevant, and completed Phase IV studies limited to “Clinicaltrials.gov”, while those not meeting these specifications were excluded. As of 3 January 2025, a total of 7,541 Phase IV clinical trials were available on “ClinicalTrials.gov”, of which 121 were related to NSCLC. Results: Six of …
The Effect Of Specialized Management Of Acute Coronary Syndrome On Patient’S Quality Of Life: A Tertiary Care Centre Study., Maan Jamjoom, Muath Alharbi, Waleed M. Malibari, Waleed Alshehri, Mohammed A. Aalem, Wafa D. Althubaity, Nouf K. Alalshaikh, Mahmoud A. Toonsi, Faisal A. Boker
The Effect Of Specialized Management Of Acute Coronary Syndrome On Patient’S Quality Of Life: A Tertiary Care Centre Study., Maan Jamjoom, Muath Alharbi, Waleed M. Malibari, Waleed Alshehri, Mohammed A. Aalem, Wafa D. Althubaity, Nouf K. Alalshaikh, Mahmoud A. Toonsi, Faisal A. Boker
Saudi Medical Journal
ABSTRACT Objectives: To assess the impact of Acute Coronary Syndrome (ACS) on quality of life (QoL) among patients at King Abdulaziz Medical City in Western Jeddah. Acute Coronary Syndrome significantly affect patients’ QoL. Many individuals experience challenges post-ACS. While previous research has identified baseline QoL, access to specialized care, and assessment tools as important factors influencing recovery, limited studies have examined how baseline QoL affects long-term outcomes. Methods: This hybrid cross-sectional study included ACS patients treated at King Abdulaziz Medical City. A sample size of 268 was calculated using RAOSOFT. A culturally tailored questionnaire, derived from the SF-36, was developed, …
An Evaluation Of Pharmaceutical Clinical Trials From Saudi Arabia Registered On Clinicaltrials.Gov: A Cross-Sectional Study, Mohammad H Aljawadi, Khalid F. Alonazi, Ibrahim M. Alsultan, Nora A Kalagi, Marwan A. Alrasheed, Abdullah M. Alhammad
An Evaluation Of Pharmaceutical Clinical Trials From Saudi Arabia Registered On Clinicaltrials.Gov: A Cross-Sectional Study, Mohammad H Aljawadi, Khalid F. Alonazi, Ibrahim M. Alsultan, Nora A Kalagi, Marwan A. Alrasheed, Abdullah M. Alhammad
Saudi Medical Journal
ABSTRACT Objectives: To evaluate clinical trials involving pharmaceutical agents conducted in Saudi Arabia and registered on ClinicalTrials.gov. Since the early 2000s, Saudi Arabia has expanded its involvement in clinical research. Recognizing the importance of clinical trials, we aimed to analyze the clinical trial landscape in the Kingdom to identify well-covered areas and potential gaps. Methods: In this descriptive cross-sectional study, ClinicalTrials.gov was used as the primary source to collect data regarding pharmacological and biological interventions conducted in Saudi Arabia between 2002 and June 2025. Results: A total of 474 pharmaceutical studies were included. Of these, 52.95% were completed, indicating moderate …
Stroke Incidence, Mortality And Disability-Adjusted Life Years (Dalys) Trends In Association With Air Pollution, Dietary And Metabolic Risk Factors In Gulf Cooperation Council Countries: Global Burden Of Disease Data Based Analysis 1990-2021, Bandar N. Aljafen, Anusha S. Meo, N. Shaikh, Sultan A. Meo
Stroke Incidence, Mortality And Disability-Adjusted Life Years (Dalys) Trends In Association With Air Pollution, Dietary And Metabolic Risk Factors In Gulf Cooperation Council Countries: Global Burden Of Disease Data Based Analysis 1990-2021, Bandar N. Aljafen, Anusha S. Meo, N. Shaikh, Sultan A. Meo
Saudi Medical Journal
ABSTRACT Objectives: To identify the primary risk factors contributing to stroke incidents and deaths, analyzing the trends and changes in regional stroke statistics between 1990 and 2021 in the Gulf Cooperation Council (GCC) countries. Methods: This longitudinal time trend study was conducted in the Department of Physiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia, from June to August 2024. The data were recorded from the Institute for Health Metrics and Evaluation (IHME) and the Global Burden of Diseases (GBD) datasets. The incidence, mortality, and disability-adjusted life year (DALY) rates of stroke in the GCC countries, Bahrain, Kuwait, Oman, …
Molecular Identification Of Respiratory Syncytial Virus, Seasonal Influenza Viruses, And Sars-Cov-2 In Respiratory Tract Infections: A Cross-Sectional Study In Taif City, Mazen M. Almehmadi, Faiha A Alharbi, Ahmad K. Shawush, Mamdouh A. Allahyani, Osama A. Abdulaziz, Ayman S. Alhazmi, Ahmad A. Aghamdi
Molecular Identification Of Respiratory Syncytial Virus, Seasonal Influenza Viruses, And Sars-Cov-2 In Respiratory Tract Infections: A Cross-Sectional Study In Taif City, Mazen M. Almehmadi, Faiha A Alharbi, Ahmad K. Shawush, Mamdouh A. Allahyani, Osama A. Abdulaziz, Ayman S. Alhazmi, Ahmad A. Aghamdi
Saudi Medical Journal
ABSTRACT Objectives: To explore the prevalence of respiratory tract infections (RTIs) in Taif via molecular diagnosis method, to enhance the clinical decision making and the need for vaccination strategies. Methods: A 5864 participants were enrolled in this study, all from Taif city. Samples were collected via nasal swab, throat swab, or sputum sample. The duration of the study were 24 months from January 2023 to December 2024. Samples were transported in viral transport medium. Then processed using GeneXpert system. Fluorescent probes detected viral RNA and reported as detected or not detected. Chi-square test was applied for statistical analysis purposes. Results: …
Diagnostic Accuracy Of Thyroid Nodules With Indeterminate Cytology When Combined With Ultrasonographic Risk, Shaza A. Samargandy, Yousef Z. Khedher, Ghaida A. Alzahrani, Hesham T. Nahhas, Mohammed A. Alshaikh, Saad Samargandy, Khalid A. Alzahrani, Aliaa H. Ghoneim
Diagnostic Accuracy Of Thyroid Nodules With Indeterminate Cytology When Combined With Ultrasonographic Risk, Shaza A. Samargandy, Yousef Z. Khedher, Ghaida A. Alzahrani, Hesham T. Nahhas, Mohammed A. Alshaikh, Saad Samargandy, Khalid A. Alzahrani, Aliaa H. Ghoneim
Saudi Medical Journal
ABSTRACT Objectives: To evaluate the added diagnostic value of ultrasonographic risk levels to cytological diagnoses in nodules with Bethesda III and IV cytology. Methods: This retrospective study was conducted in Jeddah, Saudi Arabia, and involved analyzing thyroid nodules from patients who underwent thyroidectomy between 2016 and 2023. We focused on pathology, US risk stratification based on the 2015 American Thyroid Association (ATA) guidelines, and fine-needle aspiration cytology (FNAC) using the Bethesda system. We calculated malignancy rates for each ultrasound (US) and FNAC category, with the indeterminate cytology groups defined as follicular lesions of undetermined significance (FLUS) and follicular neoplasms (FN). …
Healthcare Transformation Through The Implementation Of A New Population Health Management Approach To Achieve Saudi Arabia’S Vision 2030: The Lessons Learned In The Qassim Health Cluster, Majed S. Alharbi, Emmanuel F. Osagiede, Raed F. Al-Harbi
Healthcare Transformation Through The Implementation Of A New Population Health Management Approach To Achieve Saudi Arabia’S Vision 2030: The Lessons Learned In The Qassim Health Cluster, Majed S. Alharbi, Emmanuel F. Osagiede, Raed F. Al-Harbi
Saudi Medical Journal
ABSTRACT Objectives: To investigate how the Qassim Health Cluster (QHC) implemented population health management (PHM) in tandem with the goals of Saudi Vision 2030 and to pinpoint the main issues and lessons gained from this implementation. Methods: This research used a descriptive population study design and was conducted between November and December 2024. We collected data using a mixed-method approach, gathering qualitative data from 11 PHM implementers and secondary quantitative data from 102,946 healthcare service users. Results: Qassim Health Cluster’s PHM implementation team established a regional 5-year strategic plan to follow the national PHM framework, utilizing data-based decision-making to implement …
Characterization And Management Of Pain Across Phases Of Intraosseous Infusion In Emergency Department Patients With Non-Cardiac Arrest, Aiping Shi, Juan Chen, Xiaowei He, Chunyan Chen, Ming Sun, Wei Li, Wenxia Xu, Wei Yang, Xiaoqin Han
Characterization And Management Of Pain Across Phases Of Intraosseous Infusion In Emergency Department Patients With Non-Cardiac Arrest, Aiping Shi, Juan Chen, Xiaowei He, Chunyan Chen, Ming Sun, Wei Li, Wenxia Xu, Wei Yang, Xiaoqin Han
Saudi Medical Journal
ABSTRACT Objectives: To identify risk factors for moderate-to-severe pain during intraosseous infusion (IOI) in non-cardiac arrest patients in the emergency department (ED). Secondary aims include evaluating pain trajectory across procedural stages and assessing the efficacy of a personalized pain management strategy. Methods: This mixed-methods study analyzed 220 ED patients undergoing IOI (150 retrospective, 70 prospective). The prospective cohort was randomized to standard care (n=35) or personalized pain management (n=35). Pain was quantified using the numeric rating scale (NRS) and critical-care pain observation tool (CPOT). Results: During puncture, 35.33% (53/150) reported no/mild pain. Pain severity peaked during flushing, with 73.33% (110/150) …
Are Patients With Advanced Cancer Receiving Treatment Aligned With Their Goals?
Are Patients With Advanced Cancer Receiving Treatment Aligned With Their Goals?
Saudi Medical Journal
No abstract provided.
Who Urges Action On Hepatitis, Announcing Hepatitis D As Carcinogenic
Who Urges Action On Hepatitis, Announcing Hepatitis D As Carcinogenic
Saudi Medical Journal
No abstract provided.
Maternal Systemic Iron Homeostasis In Diabetes-In-Pregnancy: A Cross-Sectional Analytical Study From A Tertiary Health Care Centre Of South India, Kamila Thalapalliyil, Zachariah Bobby, Gowri Dorairajan, Pampa Ch. Toi
Maternal Systemic Iron Homeostasis In Diabetes-In-Pregnancy: A Cross-Sectional Analytical Study From A Tertiary Health Care Centre Of South India, Kamila Thalapalliyil, Zachariah Bobby, Gowri Dorairajan, Pampa Ch. Toi
Saudi Medical Journal
ABSTRACT Objectives: To explore whether uniform supplementation causes iron overload among a cohort of South Indian non-anemic pregnant women with diabetes-in-pregnancy (DIP). Methods: The study took place between May 2022 and May 2024 and consisted of 120 participants from 2 groups: healthy pregnant women (HP) and pregnant women with DIP. Levels of Hb and the serum indices of iron homeostasis-iron, unsaturated iron-binding capacity, total iron-binding capacity, transferrin saturation, ferritin, hepcidin, soluble transferrin receptor (sTfR), and sTfR index, were estimated. The levels of high-sensitivity C-reactive protein, indices of oxidative stress, malondialdehyde, total antioxidant status (TAS), and oxidative stress index (OSI; ratio …
Facilitators And Barriers To Mammogram Screening Uptake Among Saudi Women: A Systematic Review, Sarah A. Alkhaifi
Facilitators And Barriers To Mammogram Screening Uptake Among Saudi Women: A Systematic Review, Sarah A. Alkhaifi
Saudi Medical Journal
ABSTRACT Objectives: To evaluate current mammogram screening rates and identify barriers and facilitators for mammogram uptake among Saudi women. Methods: This systematic review was conducted in accordance with the PRISMA framework, beginning with a database search performed by 2 researchers using PubMed, PsycINFO, CINAHL Plus, and Google Scholar for pertinent studies published between 2000 and 2024. Qualitative and quantitative studies were included if they: a) were conducted in Saudi Arabia among Saudi women, b) explored factors associated with mammogram uptake among Saudi women, and c) were peer-reviewed. The socioecological model was used to thematically synthesize the results. Results: A total …
Relationship Between The Prevalence Of Breast Arterial Calcifications On Mammography And Coronary Calcifications On Chest Ct: A Cross-Sectional Study, Laila K. Ashkar, Lamia G. Jamjoom
Relationship Between The Prevalence Of Breast Arterial Calcifications On Mammography And Coronary Calcifications On Chest Ct: A Cross-Sectional Study, Laila K. Ashkar, Lamia G. Jamjoom
Saudi Medical Journal
ABSTRACT Objectives: To investigate the relationship between breast arterial calcifications (BAC) detected on mammography and coronary artery calcifications (CAC) identified on chest CT in Saudi women, focusing on prevalence, age-specific patterns, and cardiovascular risk factors. Methods: This cross-sectional study was conducted at a tertiary center in Saudi Arabia using data from hospital electronic medical records of 60 women aged 40–88 years who underwent mammography and chest CT, within the same year during the time period from January 2021 to December 2022. Data on demographics, cardiovascular risk factors, and imaging findings were collected. The association between BAC and CAC was analyzed …