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Research outputs 2022 to 2026

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Tropicalization Of Seagrass Macrophytodetritus Accumulations And Associated Food Webs, Gilles Lepoint, Glenn A. Hyndes Jan 2022

Tropicalization Of Seagrass Macrophytodetritus Accumulations And Associated Food Webs, Gilles Lepoint, Glenn A. Hyndes

Research outputs 2022 to 2026

Seagrass, systems export significant amounts of their primary production as large detritus (i.e. macrophytodetritus). Accumulations of exported macrophytodetritus (AEM) are found in many areas in coastal environment. Dead seagrass leaves are often a dominant component of these accumulations, offering shelter and/or food to numerous organisms. AEM are particular habitats, different from donor habitats (i.e. seagrass meadow, kelp or macroalgae habitats) and with their own characteristics and dynamics. They have received less attention than donor habitats despite the fact they often connect different coastal habitats, are the place of intense remineralization processes and shelter associated detritus food web. As for seagrass …


Do Personal Values Have An Effect On Self-Esteem In Middle Childhood?, Patricia R. Collins, Joanne Sneddon, Julie Ann Lee Jan 2022

Do Personal Values Have An Effect On Self-Esteem In Middle Childhood?, Patricia R. Collins, Joanne Sneddon, Julie Ann Lee

Research outputs 2022 to 2026

Research on children's values (i.e., broad motivational goals) largely focuses on whether their values have a similar theoretical pattern of organization to those of adults, whether they hold similar value priorities to adults or adolescents, and how their values relate to social behavior. However, little is known about how values relate to wellbeing in middle childhood. We examined relations between the values of children aged 6–12 and aspects of their self-esteem, including global self-worth and five domain-specific-competencies. We found global self-worth and physical appearance were positively related to self-transcendence, conservation, and openness-to-change values, and negatively related to self-enhancement values. Social …


Show, Attend And Detect: Towards Fine-Grained Assessment Of Abdominal Aortic Calcification On Vertebral Fracture Assessment Scans, Syed Zulqarnain Gilani, Naeha Sharif, David Suter, John T. Schousboe, Siobhan Reid, William D. Leslie, Joshua R. Lewis Jan 2022

Show, Attend And Detect: Towards Fine-Grained Assessment Of Abdominal Aortic Calcification On Vertebral Fracture Assessment Scans, Syed Zulqarnain Gilani, Naeha Sharif, David Suter, John T. Schousboe, Siobhan Reid, William D. Leslie, Joshua R. Lewis

Research outputs 2022 to 2026

More than 55,000 people world-wide die from Cardiovascular Disease (CVD) each day. Calcification of the abdominal aorta is an established marker of asymptomatic CVD. It can be observed on scans taken for vertebral fracture assessment from Dual Energy X-ray Absorptiometry machines. Assessment of Abdominal Aortic Calcification (AAC) and timely intervention may help to reinforce public health messages around CVD risk factors and improve disease management, reducing the global health burden related to CVDs. Our research addresses this problem by proposing a novel and reliable framework for automated “fine-grained” assessment of AAC. Inspired by the vision-to-language models, our method performs sequential …


Activity Of Newest Generation Β-Lactam/Β-Lactamase Inhibitor Combination Therapies Against Multidrug Resistant Pseudomonas Aeruginosa, Robbie R. Haines, Papanin Putsathit, Katherine A. Hammer, Anna S. Tai Jan 2022

Activity Of Newest Generation Β-Lactam/Β-Lactamase Inhibitor Combination Therapies Against Multidrug Resistant Pseudomonas Aeruginosa, Robbie R. Haines, Papanin Putsathit, Katherine A. Hammer, Anna S. Tai

Research outputs 2022 to 2026

Multidrug resistant (MDR) P. aeruginosa accounts for 35 % of all P. aeruginosa isolated from respiratory samples of patients with cystic fibrosis (CF). The usefulness of β-lactam antibiotics for treating CF, such as carbapenems and later generation cephalosporins, is limited by the development of antibacterial resistance. A proven treatment approach is the combination of a β-lactam antibiotic with a β-lactamase inhibitor. New β-lactam/β-lactamase inhibitor combinations are available, but data are lacking regarding the susceptibility of MDR CF-associated P. aeruginosa (CFPA) to these new combination therapies. In this study we determined MIC values for three new combinations; imipenem-relebactam (I-R), ceftazidime-avibactam (CZA), …


Association Between Energy Balance-Related Factors And Clinical Outcomes In Patients With Ovarian Cancer: A Systematic Review And Meta-Analysis, Stephanie Stelten, Christelle Schofield, Yvonne A. W. Hartman, Pedro Lopez, Gemma G. Kenter, Robert U. Newton, Daniel A. Galvão, Meeke Hoedjes, Dennis R. Taaffe, Luc R. C. W. Van Lonkhuijzen, Carolyn Mcintyre, Laurien M. Buffart Jan 2022

Association Between Energy Balance-Related Factors And Clinical Outcomes In Patients With Ovarian Cancer: A Systematic Review And Meta-Analysis, Stephanie Stelten, Christelle Schofield, Yvonne A. W. Hartman, Pedro Lopez, Gemma G. Kenter, Robert U. Newton, Daniel A. Galvão, Meeke Hoedjes, Dennis R. Taaffe, Luc R. C. W. Van Lonkhuijzen, Carolyn Mcintyre, Laurien M. Buffart

Research outputs 2022 to 2026

Background:

This systematic review and meta-analysis synthesized evidence in patients with ovarian cancer at diagnosis and/or during first-line treatment on; (i) the association of body weight, body composition, diet, exercise, sedentary behavior, or physical fitness with clinical outcomes; and (ii) the effect of exercise and/or dietary interventions.

Methods:

Risk of bias assessments and best-evidence syntheses were completed. Meta-analyses were performed when ≥ 3 papers presented point estimates and variability measures of associations or effects.

Results:

Body mass index (BMI) at diagnosis was not significantly associated with survival. Although the following trends were not supported by the best-evidence syntheses, the meta-analyses …


Effect Of Methyl Orange On Wettability Of Sandstone Formations: Implications For Enhanced Oil Recovery, Fatemah Alhamad, Mujahid Ali, Muhammad Ali, Hussein Abid, Hussein Hoteit, Stefan Iglauer, Alireza Keshavarz Jan 2022

Effect Of Methyl Orange On Wettability Of Sandstone Formations: Implications For Enhanced Oil Recovery, Fatemah Alhamad, Mujahid Ali, Muhammad Ali, Hussein Abid, Hussein Hoteit, Stefan Iglauer, Alireza Keshavarz

Research outputs 2022 to 2026

With the increasing global population, fossil fuel resources still represent a main contributor to the energy supply, despite the progress made in the field of renewable energies. Large quantities of residual oil from mature reservoirs cannot be produced through primary and secondary recovery methods. Among alternative recovery techniques, chemically enhanced oil recovery methods are attracting considerable interest to increase the hydrocarbon recovery from oil-bearing geological formations. The wettability of any particular formation can be used to predict the oil recovery factor of a reservoir based on its wetting state. However, due to the complex nature of geological porous media, special …


Exploring Food Supply Chain Trends In The Covid-19 Era: A Bibliometric Review, Abderahman Rejeb, Karim Rejeb, Andrea Appolloni, Mohammad Iranmanesh, Horst Treiblmaier, Sandeep Jagtap Jan 2022

Exploring Food Supply Chain Trends In The Covid-19 Era: A Bibliometric Review, Abderahman Rejeb, Karim Rejeb, Andrea Appolloni, Mohammad Iranmanesh, Horst Treiblmaier, Sandeep Jagtap

Research outputs 2022 to 2026

Recently, the food supply chain (FSC) has been severely disrupted due to the COVID-19 pandemic, putting the vital flow of food products from farmers and producers to the ultimate consumers at risk. Furthermore, due to the pandemic, several food organizations have been prompted to rethink their strategies for the future. Although the literature on FSC research in the COVID-19 era is increasing, no attempt has been made to summarize this stream of research using bibliometric techniques. This paper fills this knowledge gap and looks at the current scholarly discourse around the FSC and COVID-19. Applying bibliometric techniques, 287 journal articles …


How Can We Address The Wicked Problem Of University Student Attrition? A Bed (Early Childhood) Case Study, Gillian Kirk Jan 2022

How Can We Address The Wicked Problem Of University Student Attrition? A Bed (Early Childhood) Case Study, Gillian Kirk

Research outputs 2022 to 2026

Student retention in education courses is a political imperative. This research examined the wicked problem of attrition in a Bachelor of Education (Early Childhood Studies) course, drawing on the experiences of three different groups of students studying early childhood. The participants from each study represented different student groups within the course, which included all female (n = 20), all male (n = 6) and all mid-year entry students (n = 10). A qualitative methodology was employed to capture students’ university experiences and their perceptions of events at university. The research generated a unique theoretical framework examining the intersection between student …


Realising Curriculum Possibilities In Wales: Teachers’ Initial Experiences Of Re-Imagining Secondary Physical Education, David Aldous, Victoria Evans, Rhys Lloyd, Fiona Heath-Diffey, Fiona Chambers Jan 2022

Realising Curriculum Possibilities In Wales: Teachers’ Initial Experiences Of Re-Imagining Secondary Physical Education, David Aldous, Victoria Evans, Rhys Lloyd, Fiona Heath-Diffey, Fiona Chambers

Research outputs 2022 to 2026

This paper provides insight into secondary Physical Education (PE) teachers’ experiences of beginning to re-imagine secondary physical education provision in light of the new Curriculum for Wales, 2022 (CfW). Data were generated through analysis of semi-structured interviews (n = 5) with secondary PE teachers who participated in three workshops which uses a design-thinking methodology. Informed by Ball and colleagues’ conceptualisation of policy work, findings draw attention towards how engagement in the workshops provided a foundation for the participants to begin interpretation and translation of the new CfW and consider re-imagining existing PE provision within the school context. Participants’ interpretations of …


The Intersection Of The Rule In Yerkey V Jones And Contemporary Anti-Discrimination Law In Australia – Can The ‘Special Wives’ Equity Survive?, Kenneth Yin, Mostafa M. Naser Jan 2022

The Intersection Of The Rule In Yerkey V Jones And Contemporary Anti-Discrimination Law In Australia – Can The ‘Special Wives’ Equity Survive?, Kenneth Yin, Mostafa M. Naser

Research outputs 2022 to 2026

The High Court in Yerkey v Jones considered the enforceability of a guarantee provided by a married woman to secure her husband’s debts. Dixon J said that although the relationship of husband and wife did not give rise to a presumption of undue influence, the law had never been divested completely of ‘the equitable presumption of an invalidating tendency’. Dixon J’s formulation was essentially adopted by the majority justices in Garcia v National Australia Bank and their judgment thus represents the definitive endorsement of Dixon J’s view. Kirby
J on the other hand rejected ‘the stereotype underlying Yerkey’, which he …


A Review Of Arthritis Diagnosis Techniques In Artificial Intelligence Era: Current Trends And Research Challenges, Maleeha Imtiaz, Syed Afaq Ali Shah, Zia Ur Rehman Jan 2022

A Review Of Arthritis Diagnosis Techniques In Artificial Intelligence Era: Current Trends And Research Challenges, Maleeha Imtiaz, Syed Afaq Ali Shah, Zia Ur Rehman

Research outputs 2022 to 2026

Deep learning, a branch of artificial intelligence, has achieved unprecedented performance in several domains including medicine to assist with efficient diagnosis of diseases, prediction of disease progression and pre-screening step for physicians. Due to its significant breakthroughs, deep learning is now being used for the diagnosis of arthritis, which is a chronic disease affecting young to aged population. This paper provides a survey of recent and the most representative deep learning techniques (published between 2018 to 2020) for the diagnosis of osteoarthritis and rheumatoid arthritis. The paper also reviews traditional machine learning methods (published 2015 onward) and their application for …


Assessment Of Hole Quality, Thermal Analysis, And Chip Formation During Dry Drilling Process Of Gray Cast Iron Astm A48, Numan Habib, Aamer Sharif, Aqib Hussain, Muhammad Aamir, Khaled Giasin, Danil Yurievich Pimenov Jan 2022

Assessment Of Hole Quality, Thermal Analysis, And Chip Formation During Dry Drilling Process Of Gray Cast Iron Astm A48, Numan Habib, Aamer Sharif, Aqib Hussain, Muhammad Aamir, Khaled Giasin, Danil Yurievich Pimenov

Research outputs 2022 to 2026

The cutting parameters in drilling operations are important for high-quality holes and productivity improvement in any manufacturing industry. This study investigates the effects of spindle speed and feed rate on temperature, surface roughness, hole size, circularity, and chip formation during dry drilling of gray cast iron ASTM A48. The results showed that the temperature increased as spindle speed and feed rate increased. The surface roughness had an inverse relationship with the spindle speed and direct relation with the feed rate. Furthermore, hole size increased with increased spindle speed and decreased as the feed rate increased, while hole circularity decreased with …


Exhibiting Slavery: Biographical Approaches, Paul L. Arthur, Isobel Smith Jan 2022

Exhibiting Slavery: Biographical Approaches, Paul L. Arthur, Isobel Smith

Research outputs 2022 to 2026

Within museums, interpretation and curation have increasingly employed personal stories and intimate storytelling to present broader narratives about the past. This article explores some of the opportunities and challenges of biographical storytelling in museums and public sites of memory that engage with the issue of slavery, analysing Australian exhibitions alongside international contexts and theories of museology, historiography and memory. It will look at representations of historical and modern slavery in Australia, as well as global representations of the transatlantic slave trade and other traumatic histories such as the Holocaust. The discussion explores the potential for personal counter-narratives, the reimagining of …


Identifying Modifiable Features Of Home Bowel Cancer Screening Kits To Facilitate Use: Consumer Perspectives, Belinda C. Goodwin, Bianca Viljoen, Larry Myers, Michael J. Ireland, Jeff Dunn, Suzanne K. Chambers, Nicholas Ralph, Joanne F. Aitken Jan 2022

Identifying Modifiable Features Of Home Bowel Cancer Screening Kits To Facilitate Use: Consumer Perspectives, Belinda C. Goodwin, Bianca Viljoen, Larry Myers, Michael J. Ireland, Jeff Dunn, Suzanne K. Chambers, Nicholas Ralph, Joanne F. Aitken

Research outputs 2022 to 2026

Objectives:

Despite the widely publicised health benefits of participation in bowel cancer screening, only 43.5% of recipients participate in the Australian National Bowel Cancer Screening Program (NBCSP). Through consultation with kit recipients, this study aimed to identify features of home bowel screening kits that could be modified to increase their use.

Method:

Participants (n = 25) were presented with nine different bowel cancer screening kits and asked to identify features of each kit that might prevent or promote their use. Responses were coded using content analysis, and a narrative synthesis is presented summarising preferences relating to each element of the …


Maya-Kwobabiny: Re-Embedding Language At Kepa Kurl, Western Australia, Clint Bracknell, Amy Budrikis, Roma Yibiyung Winmar Jan 2022

Maya-Kwobabiny: Re-Embedding Language At Kepa Kurl, Western Australia, Clint Bracknell, Amy Budrikis, Roma Yibiyung Winmar

Research outputs 2022 to 2026

This paper describes a Nyungar language revitalisation project in the southern region of Western Australia conducted in partnership between a university research team and the Esperance Tjaltjraak Native Title Aboriginal Corporation. It discusses how linguistic analysis of historical Nyungar documentation was essential to addressing community aims of re-embedding the language into the community, developing and using pedagogical resources, and exploring new domains for language use. In particular, this paper focuses on the community’s desire for the reclamation of a dialectal flavour of Nyungar that is distinctive to the Esperance region, and the factors contributing to a successful partnership between the …


Myth-Busting In An Aboriginal Pre-University Bridging Program: Embedding Transformative Learning Pedagogy, Rebecca Bennett, Karin Strehlow, Braden Hill Jan 2022

Myth-Busting In An Aboriginal Pre-University Bridging Program: Embedding Transformative Learning Pedagogy, Rebecca Bennett, Karin Strehlow, Braden Hill

Research outputs 2022 to 2026

Pre-university bridging programs can address the significant under-representation of Indigenous students in Australian universities by providing culturally supported alternative pathways into undergraduate study. However, successful completion of bridging programs does not always correlate with university enrolment for Indigenous students. This paper offers a pedagogical rationale for an Indigenous bridging program that aims to address this discrepancy. The program curriculum challenges deficit myths about Aboriginal and Torres Strait Islander Australians and education, while developing foundational academic skills for university study. Leveraging Transformative Learning and Cultural Interface theories, the program aims to empower students with the opportunity to develop their own narratives …


Perspectives On Wider Integration Of The Health-Assistive Smart Home, Gordana Dermody, Jenna Mikus, Davina Porock, Dov Sugarman, Naeem K. Janjua, Christopher How, Roschelle Fritz Jan 2022

Perspectives On Wider Integration Of The Health-Assistive Smart Home, Gordana Dermody, Jenna Mikus, Davina Porock, Dov Sugarman, Naeem K. Janjua, Christopher How, Roschelle Fritz

Research outputs 2022 to 2026

Most older adults desire to be as independent as possible and remain living in their ancestral home as they age. Aging-in-place maximizes the independence of older adults, enhancing their wellbeing and quality of life while decreasing the financial burden of residential care costs. However, due to chronic disease, multimorbidity, and age-related changes, appropriate conditions are required to make aging-in-place possible. Remote monitoring with smart home technologies could provide the infrastructure that enables older adults to remain living independently in their own homes safely. The health-assistive smart home shows great promise, but there are challenges to integrating smart homes on a …


Speaking Of Online Learning: Alternative Practice-Based Learning Experiences For Speech Pathologists In Australia, Ghana And Hong Kong, Jemma Skeat, Josephine Ohenewa Bampoe, Susan Booth, Emily Brogan, Maya Conway, Rachel Davenport, Simone Howells, Peggy Kan, Michelle Krahe, Sally Hewat, Abigail Lewis, Alex Little, Joanne Walters, Gwendalyn Webb, Nikki Worthington Jan 2022

Speaking Of Online Learning: Alternative Practice-Based Learning Experiences For Speech Pathologists In Australia, Ghana And Hong Kong, Jemma Skeat, Josephine Ohenewa Bampoe, Susan Booth, Emily Brogan, Maya Conway, Rachel Davenport, Simone Howells, Peggy Kan, Michelle Krahe, Sally Hewat, Abigail Lewis, Alex Little, Joanne Walters, Gwendalyn Webb, Nikki Worthington

Research outputs 2022 to 2026

Speech Pathology programs usually send students to workplaces to learn clinical skills necessary for practice. During COVID-19, programs needed to respond quickly to ensure that students continued to gain the necessary experiences and skills required to progress through their program and graduate as clinicians, while simultaneously complying with COVID-19 requirements. Case studies from seven different universities in Australia, Ghana and Hong Kong described the diverse ways in which placements were adapted to be COVID-safe, taking into account local needs. Some practices which had been included in placement education prior to the pandemic, such as telepractice and simulation-based learning, were extended …


Statistical Analysis Plan For The Stepped-Wedge Clinical Trial Healing Right Way - Enhancing Rehabilitation Services For Aboriginal Australians After Brain Injury, Elizabeth Armstrong, Tapan Rai, Deborah Hersh, Sandra Thompson, Juli Coffin, Natalie Ciccone, Leon Flicker, Dominique Cadilhac, Erin Godecke, Deborah Woods, Colleen Hayward, Graeme J. Hankey, Meaghan Mcallister, Judith Katzenellenbogen Jan 2022

Statistical Analysis Plan For The Stepped-Wedge Clinical Trial Healing Right Way - Enhancing Rehabilitation Services For Aboriginal Australians After Brain Injury, Elizabeth Armstrong, Tapan Rai, Deborah Hersh, Sandra Thompson, Juli Coffin, Natalie Ciccone, Leon Flicker, Dominique Cadilhac, Erin Godecke, Deborah Woods, Colleen Hayward, Graeme J. Hankey, Meaghan Mcallister, Judith Katzenellenbogen

Research outputs 2022 to 2026

Background: Aboriginal Australians are known to suffer high levels of acquired brain injury (stroke and traumatic brain injury) yet experience significant barriers in accessing rehabilitation services. The aim of the Healing Right Way trial is to evaluate a culturally secure intervention for Aboriginal people with newly acquired brain injury to improve their rehabilitation experience and quality of life. Following publication of the trial protocol, this paper outlines the statistical analysis plan prior to locking the database. Methods: The trial involves a stepped wedge design with four steps over 3 years. Participants were 108 adult Aboriginal Australians admitted to one of …


The Knowledge Produced Through Student Drawings, Vesife Hatisaru Jan 2022

The Knowledge Produced Through Student Drawings, Vesife Hatisaru

Research outputs 2022 to 2026

Drawings have been extensively used as a research method to gather data from research participants including school students regarding their perceptions of mathematics and its teaching and learning. What is valued in drawing-based research in mathematics education, and what kind of knowledge is produced through student drawings, however, is not known. This study examines drawing-based research studies to understand these questions by applying a novel framework – the legitimation code theory (LCT). The study focuses on two cases: one of which looked at middle school students’ images of mathematicians (draw a mathematician) and the other examined the same age group …


Deep Learning Inspired Feature Engineering For Classifying Tremor Severity, Ahmed Al Taee, Seyedehmarzieh Hosseini, Rami N. Khushaba, Tanveer Zia, Chin-Teng Lin, Adel Al-Jumaily Jan 2022

Deep Learning Inspired Feature Engineering For Classifying Tremor Severity, Ahmed Al Taee, Seyedehmarzieh Hosseini, Rami N. Khushaba, Tanveer Zia, Chin-Teng Lin, Adel Al-Jumaily

Research outputs 2022 to 2026

Bio-signals pattern recognition systems can be impacted by several factors with a potential to limit their associated performance and clinical translation. Among these factors, selecting the optimum feature extraction method, that can effectively exploit the interaction between the temporal and spatial information, is the most prominent. Despite the potential of deep learning (DL) models for extracting temporal, spatial, or temporal-spatial information, they are typically restricted by their need for a large amount of training data. The deep wavelet scattering transform (WST) is a relatively recent advancement within the DL literature to replace expensive convolution neural networks models with computationally less …


Sport-Specific Crossover Point Differences During A Maximal Oxygen Consumption Test, Joseph R. Stanzione, George A. Brooks, Michael L. Bruneau, Duncan N. French, Jennifer A. Nasser, Sinclair A. Smith, Stella L. Volpe Jan 2022

Sport-Specific Crossover Point Differences During A Maximal Oxygen Consumption Test, Joseph R. Stanzione, George A. Brooks, Michael L. Bruneau, Duncan N. French, Jennifer A. Nasser, Sinclair A. Smith, Stella L. Volpe

Research outputs 2022 to 2026

Introduction/Purpose: The crossover point occurs during exercise when one transitions energy substrates from fat to carbohydrate predominance. The crossover point varies in an intensity-dependent manner; however, less is known about its specificity in sports with varying metabolic demands. The purpose of our study was to determine if various sports yield differences in the time to crossover and heart rate and percentage of maximal oxygen consumption (V O2max) at crossover during a standardized exercise protocol.

Methods: A total of 77 athletes (39 women, 38 men; 39.1 + 10.4 yr of age) were measured for respiratory exchange ratio during a modified Taylor …


Patch Dynamics Driven By Wave Exposure In Subtidal Temperate Seaweeds Are Exacerbated By Warming Oceans, Yannick Mulders, Lydiane Mattio, Julia C. Phillips, Paul S. Lavery, Gary A. Kendrick, Thomas Wernberg Jan 2022

Patch Dynamics Driven By Wave Exposure In Subtidal Temperate Seaweeds Are Exacerbated By Warming Oceans, Yannick Mulders, Lydiane Mattio, Julia C. Phillips, Paul S. Lavery, Gary A. Kendrick, Thomas Wernberg

Research outputs 2022 to 2026

Over the past decades, ocean temperatures have been steadily increasing and are projected to continue to do so, stressing many temperate marine organisms. Changing temperatures do not affect ecosystems in isolation, but interact with many other factors in shaping ecological communities. We investigated the changes over 2 decades in subtidal temperate seaweed communities over a wave exposure gradient in Western Australia, a global warming hotspot. We found higher diversity in the seaweed community and a higher proportion of biomass of species with a warm affinity (expressed as the tropicalization index: TI) over time. There was no decline in biomass of …


Exploring Discordant Low Amyloid Beta And High Neocortical Tau Positron Emission Tomography Cases, Natasha Krishnadas, Vincent Doré, Simon M. Laws, Tenielle Porter, Fiona Lamb, Svetlana Bozinovski, Victor L. Villemagne, Christopher C. Rowe Jan 2022

Exploring Discordant Low Amyloid Beta And High Neocortical Tau Positron Emission Tomography Cases, Natasha Krishnadas, Vincent Doré, Simon M. Laws, Tenielle Porter, Fiona Lamb, Svetlana Bozinovski, Victor L. Villemagne, Christopher C. Rowe

Research outputs 2022 to 2026

Introduction: Neocortical 3R4R (3-repeat/4-repeat) tau aggregates are rarely observed in the absence of amyloid beta (Aβ). 18F-MK6240 binds specifically to the 3R4R form of tau that is characteristic of Alzheimer's disease (AD). We report four cases with negative Aβ, but positive tau positron emission tomography (PET) findings. Methods: All Australian Imaging, Biomarkers and Lifestyle study of aging (AIBL) study participants with Aβ (18F-NAV4694) and tau (18F-MK6240) PET scans were included. Centiloid < 25 defined negative Aβ PET (Aβ–). The presence of neocortical tau was defined quantitatively and visually. Results: Aβ– PET was observed in 276 participants. Four of these participants (one cognitively unimpaired [CU], two mild cognitive impairment [MCI], one AD) had tau tracer retention in a pattern consistent with Braak tau stages V to VI. Fluid biomarkers supported a diagnosis of AD. In silico analysis of APP, PSEN1, PSEN2, and MAPT genes did not identify relevant functional mutations. Discussion: Discordant cases were infrequent (1.4% of all Aβ– participants). In these cases, the Aβ PET ligand may not be detecting the Aβ that is present.


Genes Involved In Platelet Aggregation And Activation Are Downregulated During Acute Anaphylaxis In Humans, Francesca M. Mcgrath, Abbie Francis, Daniel M. Fatovich, Stephen P. J. Macdonald, Glenn Arendts, Andrew J. Woo, Erika Bosio Jan 2022

Genes Involved In Platelet Aggregation And Activation Are Downregulated During Acute Anaphylaxis In Humans, Francesca M. Mcgrath, Abbie Francis, Daniel M. Fatovich, Stephen P. J. Macdonald, Glenn Arendts, Andrew J. Woo, Erika Bosio

Research outputs 2022 to 2026

Objective: Mechanisms underlying the anaphylactic reaction in humans are not fully understood. Here, we aimed at improving our understanding of anaphylaxis by investigating gene expression changes. Methods: Microarray data set GSE69063 was analysed, describing emergency department (ED) patients with severe anaphylaxis (n = 12), moderate anaphylaxis (n = 6), sepsis (n = 20) and trauma (n = 11). Samples were taken at ED presentation (T0) and 1 h later (T1). Healthy controls were age and sex matched to ED patient groups. Gene expression changes were determined using limma, and pathway analysis applied. Differentially expressed genes were validated in an independent …


Advancing Feminist Innovation In Sport Studies: A Transdisciplinary Dialogue On Gender, Health And Wellbeing, Holly Thorpe, Sheree Bekker, Simone Fullagar, Nonhlanhla Mkumbuzi, Sophia Nimphius, Madeleine Pape, Stacy T. Sims, A. Travers Jan 2022

Advancing Feminist Innovation In Sport Studies: A Transdisciplinary Dialogue On Gender, Health And Wellbeing, Holly Thorpe, Sheree Bekker, Simone Fullagar, Nonhlanhla Mkumbuzi, Sophia Nimphius, Madeleine Pape, Stacy T. Sims, A. Travers

Research outputs 2022 to 2026

Athlete health and wellbeing requires a holistic, multidimensional approach to understanding, supporting, and treating individual athletes. Building more supportive, inclusive, and equitable environments for the health and wellbeing of women and gender expansive people further requires gender-responsive approaches that promote broader cultural change. Feminist sport and exercise medicine practitioners, sports scientists, and social science researchers are increasingly coming together in their efforts to do this work. However, working across disciplines inevitably includes an array of ontological, epistemological, and political challenges. In this paper, we offer a curated ‘dialogue’ with a group of feminist scholars engaged in research and practice across …


A Review On Security Issues And Solutions Of The Internet Of Drones, Wencheng Yang, Song Wang, Xuefei Yin, Xu Wang, Jiankun Hu Jan 2022

A Review On Security Issues And Solutions Of The Internet Of Drones, Wencheng Yang, Song Wang, Xuefei Yin, Xu Wang, Jiankun Hu

Research outputs 2022 to 2026

The Internet of Drones (IoD) has attracted increasing attention in recent years because of its portability and automation, and is being deployed in a wide range of fields (e.g., military, rescue and entertainment). Nevertheless, as a result of the inherently open nature of radio transmission paths in the IoD, data collected, generated or handled by drones is plagued by many security concerns. Since security and privacy are among the foremost challenges for the IoD, in this paper we conduct a comprehensive review on security issues and solutions for IoD security, discussing IoD-related security requirements and identifying the latest advancement in …


A Low-Cost Machine Learning Based Network Intrusion Detection System With Data Privacy Preservation, Jyoti Fakirah, Lauhim Mahfuz Zishan, Roshni Mooruth, Michael L. Johnstone, Wencheng Yang Jan 2022

A Low-Cost Machine Learning Based Network Intrusion Detection System With Data Privacy Preservation, Jyoti Fakirah, Lauhim Mahfuz Zishan, Roshni Mooruth, Michael L. Johnstone, Wencheng Yang

Research outputs 2022 to 2026

Network intrusion is a well-studied area of cyber security. Current machine learning-based network intrusion detection systems (NIDSs) monitor network data and the patterns within those data but at the cost of presenting significant issues in terms of privacy violations which may threaten end-user privacy. Therefore, to mitigate risk and preserve a balance between security and privacy, it is imperative to protect user privacy with respect to intrusion data. Moreover, cost is a driver of a machine learning-based NIDS because such systems are increasingly being deployed on resource-limited edge devices. To solve these issues, in this paper we propose a NIDS …


Exploring Issues Of Resilience And Technology Use For Older People - A Scoping Review Protocol, Timothy J. Smith, Khui Hung Lee, Kan Yu, Leisa Armstrong, David M. Cook Jan 2022

Exploring Issues Of Resilience And Technology Use For Older People - A Scoping Review Protocol, Timothy J. Smith, Khui Hung Lee, Kan Yu, Leisa Armstrong, David M. Cook

Research outputs 2022 to 2026

The aim of this scoping review is to understand the extent of issues of resilience implied by the interactions of older people with financial, social, and health related technologies. Older people aged 60+, technology use or non-use, and issues of resilience studied over the last four years (2019-2022) demarcate the scope of this review. Key exclusion criteria are older adults living in long-term care facilities, nursing homes, care homes and hospital in-patients. It also excludes studies on the perspectives of older peoples’ clinicians. The review will be carried out according to the Joanna Briggs Institute (JBI) scoping review methodology. The …


The Evolution Of Mining Employment During The Resource Boom And Bust Cycle In Australia, Nam Foo, Ruhul Salim Jan 2022

The Evolution Of Mining Employment During The Resource Boom And Bust Cycle In Australia, Nam Foo, Ruhul Salim

Research outputs 2022 to 2026

Mining employment in Australia can be cyclical and volatile. Since the gold rush in the 1850s, Australia has experienced two major mining booms. The first was in the 1970s and the second (i.e., the mineral boom) was in the mid-2000s and so it is important to have a discussion about trends in the Australian mining industry and about employment during mining cycles. This study employs Australian mining industry data to investigate sectoral labor mobility (moving from one industry to another) when the business cycles have changed. This research has used quarterly data from 1950q1 to 2018q4 for several industries such …