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Realistic Motion Avatars Are The Future For Social Interaction In Virtual Reality, Shane L. Rogers, Rebecca Broadbent, Jemma Brown, Allan Fraser, Craig P. Speelman Jan 2022

Realistic Motion Avatars Are The Future For Social Interaction In Virtual Reality, Shane L. Rogers, Rebecca Broadbent, Jemma Brown, Allan Fraser, Craig P. Speelman

Research outputs 2022 to 2026

This study evaluated participant self-reported appraisal of social interactions with another person in virtual reality (VR) where their conversational partner was represented by a realistic motion avatar. We use the term realistic motion avatar because: 1. The avatar was modelled to look like the conversational partner it represented, and 2. Full face and body motion capture was utilised so that the avatar mimicked the facial and body language of the conversational partner in real-time. We compared social interaction in VR with face-to-face interaction across two communicative contexts: 1. Getting acquainted conversation, and 2. A structured interview where the participant engaged …


A Translational Research Framework For Nurse Practitioners, Mary Ryder, Elisabeth Jacob Jan 2022

A Translational Research Framework For Nurse Practitioners, Mary Ryder, Elisabeth Jacob

Research outputs 2022 to 2026

Aims This study aims to explore a proposed translational research continuum for nurse practitioners. Background Nurse practitioners are acknowledged as clinical leaders responsible for transforming health care delivery. It is important that nurse practitioners contribute to health care knowledge using scientific processes for the implementation of evidence-based practice and evaluation of outcomes of interventions for their patient groups. Evaluation This paper provides a review of translational research literature including implementation science to align nurse practitioner activities to a modified translational research framework. Key Issues A translational research framework has the potential to strengthen nursing research in the nurse practitioner role. …


Developing, Monitoring, And Reporting Of Fidelity In Aphasia Trials: Core Recommendations From The Collaboration Of Aphasia Trialists (Cats) Trials For Aphasia Panel, Nicholas Behn, Madeleine Harrison, Marian C. Brady, Caterina Breitenstein, Marcella Carragher, Julius Fridriksson, Erin Godecke, Argye Hillis, Helen Kelly, Rebecca Palmer, Miranda L. Rose, Shirley Thomas, Donna Tippett, Linda Worrall, Frank Becker, Katerina Hilari Jan 2022

Developing, Monitoring, And Reporting Of Fidelity In Aphasia Trials: Core Recommendations From The Collaboration Of Aphasia Trialists (Cats) Trials For Aphasia Panel, Nicholas Behn, Madeleine Harrison, Marian C. Brady, Caterina Breitenstein, Marcella Carragher, Julius Fridriksson, Erin Godecke, Argye Hillis, Helen Kelly, Rebecca Palmer, Miranda L. Rose, Shirley Thomas, Donna Tippett, Linda Worrall, Frank Becker, Katerina Hilari

Research outputs 2022 to 2026

Background:

Developing, monitoring, and reporting of fidelity are essential and integral components to the design of randomised controlled trials (RCTs) in stroke and aphasia. Treatment fidelity refers to the degree to which an intervention is delivered as intended and is directly related to the quality of the evidence generated by RCTs. Clear documentation of treatment fidelity in trials assists in the evaluation of the clinical implications of potential benefits attributed to the intervention. Consideration of the implementation requirements of a research-based intervention as intended in a clinical context is necessary to achieve similar outcomes for a clinical population. Despite this, …


Future Perspectives Of Uveal Melanoma Blood Based Biomarkers, Aaron B. Beasley, Fred K. Chen, Timothy W. Isaacs, Elin S. Gray Jan 2022

Future Perspectives Of Uveal Melanoma Blood Based Biomarkers, Aaron B. Beasley, Fred K. Chen, Timothy W. Isaacs, Elin S. Gray

Research outputs 2022 to 2026

Uveal melanoma (UM) is the most common primary intraocular malignancy affecting adults. Despite successful local treatment of the primary tumour, metastatic disease develops in up to 50% of patients. Metastatic UM carries a particularly poor prognosis, with no effective therapeutic option available to date. Genetic studies of UM have demonstrated that cytogenetic features, including gene expression, somatic copy number alterations and specific gene mutations can allow more accurate assessment of metastatic risk. Pre-emptive therapies to avert metastasis are being tested in clinical trials in patients with high-risk UM. However, current prognostic methods require an intraocular tumour biopsy, which is a …


Edge-Iiotset: A New Comprehensive Realistic Cyber Security Dataset Of Iot And Iiot Applications For Centralized And Federated Learning, Mohamed A. Ferrag, Othmane Friha, Djallel Hamouda, Leandros Maglaras, Helge Janicke Jan 2022

Edge-Iiotset: A New Comprehensive Realistic Cyber Security Dataset Of Iot And Iiot Applications For Centralized And Federated Learning, Mohamed A. Ferrag, Othmane Friha, Djallel Hamouda, Leandros Maglaras, Helge Janicke

Research outputs 2022 to 2026

In this paper, we propose a new comprehensive realistic cyber security dataset of IoT and IIoT applications, called Edge-IIoTset, which can be used by machine learning-based intrusion detection systems in two different modes, namely, centralized and federated learning. Specifically, the dataset has been generated using a purpose-built IoT/IIoT testbed with a large representative set of devices, sensors, protocols and cloud/edge configurations. The IoT data are generated from various IoT devices (more than 10 types) such as Low-cost digital sensors for sensing temperature and humidity, Ultrasonic sensor, Water level detection sensor, pH Sensor Meter, Soil Moisture sensor, Heart Rate Sensor, Flame …


Sulfur Compounds: From Plants To Humans And Their Role In Chronic Disease Prevention, Caroline R. Hill, Armaghan Shafaei, Lois Balmer, Joshua R. Lewis, Jonathan M. Hodgson, A. Harvey Millar, Lauren C. Blekkenhorst Jan 2022

Sulfur Compounds: From Plants To Humans And Their Role In Chronic Disease Prevention, Caroline R. Hill, Armaghan Shafaei, Lois Balmer, Joshua R. Lewis, Jonathan M. Hodgson, A. Harvey Millar, Lauren C. Blekkenhorst

Research outputs 2022 to 2026

Sulfur is essential for the health of plants and is an indispensable dietary component for human health and disease prevention. Its incorporation into our food supply is heavily reliant upon the uptake of sulfur into plant tissue and our subsequent intake. Dietary requirements for sulfur are largely calculated based upon requirements for the sulfur-containing amino acids (SAA), cysteine and methionine, to meet the demands for synthesis of proteins, enzymes, co-enzymes, vitamins, and hormones. SAA are found in abundance in animal sources and are relatively low in plants. However, some plants, particularly cruciferous and allium vegetables, produce many protective sulfur-containing secondary …


An Initial Investigation Into Parental Perceptions Surrounding The Impact Of Mobile Media Use On Child Behavior And Executive Functioning, Stephanie C. Milford, Lynette Vernon, Joseph J. Scott, Nicola F. Johnson Jan 2022

An Initial Investigation Into Parental Perceptions Surrounding The Impact Of Mobile Media Use On Child Behavior And Executive Functioning, Stephanie C. Milford, Lynette Vernon, Joseph J. Scott, Nicola F. Johnson

Research outputs 2022 to 2026

Children demonstrate increasing early engagement with mobile media facilitated by its portability and interactivity. Parents are known to employ a range of mediation strategies for mobile media use but continue to have limited awareness about the impact of mobile media on their child’s executive functioning. Mobile media use has previously been shown to be negatively correlated with the executive functioning development of a child; however, little is known of how parents approach their child’s mobile media use. This study employed a survey design (N = 281) to examine how parents access information related to mobile media and document their perspectives …


Saliva Cortisol In Girls With Functional Abdominal Pain Disorders: A Randomized Controlled Dance And Yoga Intervention, Elin Areskog Sandberg, Anna Duberg, Ulrika Lorenzon Fagerberg, Evalotte Morelius, Stefan Särnblad Jan 2022

Saliva Cortisol In Girls With Functional Abdominal Pain Disorders: A Randomized Controlled Dance And Yoga Intervention, Elin Areskog Sandberg, Anna Duberg, Ulrika Lorenzon Fagerberg, Evalotte Morelius, Stefan Särnblad

Research outputs 2022 to 2026

Introduction: Functional abdominal pain disorders (FAPDs) are common among girls and has been associated with stress. Cortisol is one of the major stress hormones. Dance and yoga have been shown to reduce abdominal pain among girls with FAPDs. Aim: To investigate the effect of an 8-month intervention with dance and yoga on cortisol levels in saliva among girls with FAPDs. Methods: A total of 121 girls aged 9–13 years with irritable bowel syndrome (IBS) or functional abdominal pain were included in the study. Participants were randomized into an intervention group and a control group. The intervention group attended a combined …


Nationwide Industry-Led Community Exercise Program For Men With Locally Advanced, Relapsed, Or Metastatic Prostate Cancer On Androgen-Deprivation Therapy, Oliver Schumacher, Daniel A. Galvao, Dennis R. Taaffe, Nigel Spry, Dickon Hayne, Colin Tang, Raphael Chee, Robert U. Newton Jan 2022

Nationwide Industry-Led Community Exercise Program For Men With Locally Advanced, Relapsed, Or Metastatic Prostate Cancer On Androgen-Deprivation Therapy, Oliver Schumacher, Daniel A. Galvao, Dennis R. Taaffe, Nigel Spry, Dickon Hayne, Colin Tang, Raphael Chee, Robert U. Newton

Research outputs 2022 to 2026

Purpose:

Androgen-deprivation therapy in patients with prostate cancer (PCa) is associated with considerable side effects and secondary comorbidities such as overweight/obesity and cardiovascular disease. The aim of this study was to investigate the effectiveness of an industry-led, treatment-integrated, community-based exercise program on outcomes of body weight, cardiovascular health, and physical function.

Patients and Methods:

PCa patients with locally advanced, relapsed, or metastatic disease receiving leuprorelin acetate were enrolled across multiple sites in Australia and assigned supervised group exercise undertaken weekly or biweekly (ie, 16 exercise sessions in total) for 10-18 weeks, consisting of aerobic and resistance training performed at moderate-to-vigorous …


Curriculum Reform In Wales: Physical Education Teacher Educators' Negotiation Of Policy Positions, David Aldous, Victoria Evans, Dawn Penney Jan 2022

Curriculum Reform In Wales: Physical Education Teacher Educators' Negotiation Of Policy Positions, David Aldous, Victoria Evans, Dawn Penney

Research outputs 2022 to 2026

This paper reports on research that explored the experiences of secondary Physical Education Teacher Education (PETE) professionals' simultaneous negotiation and implementation of the new Curriculum for Wales (CfW) Health and Well-Being (HWB) Area of Learning and Experience (AoLE) and policies focused on the transformation of Initial Teacher Education (ITE) in Wales. The study was an exploratory case study of PETE professionals working within one university's ITE programme. Data were generated through documentary analysis of PETE and ITE programme materials and semi-structured interviews with staff involved in programme management and delivery. Data analysis employed Ball and colleagues' conceptualisation of policy actors …


Regulatory Flexibilities And Access To Covid-19 Vaccines During The Pandemic In Bhutan, Dawa Tshering, Pelden Chejor Jan 2022

Regulatory Flexibilities And Access To Covid-19 Vaccines During The Pandemic In Bhutan, Dawa Tshering, Pelden Chejor

Research outputs 2022 to 2026

Summary Coronavirus disease 2019 (COVID-19) is rapidly evolving with millions of cases and death reported globally. The first-ever case of COVID-19 in Bhutan was confirmed on 5 March 2020 in a 76-year-old American tourist. The national regulatory authorities have implemented varying degrees of regulatory flexibilities to prevent unnecessary death by ensuring timely access to medical products and technologies during the pandemic. The Drug Regulatory Authority of Bhutan, as a national medicines regulatory agency responsible for ensuring the quality of medical products has implemented several regulatory mechanisms to ensure access to medical products including COVID-19 vaccines during the pandemic. In this …


Psychological Distress And Quality Of Life In Asymptomatic Adults Following Provision Of Imaging Results For Prevention Of Cardiovascular Disease Events: A Scoping Review, Reindolf Anokye, Ben Jackson, James Dimmock, Joanne M. Dickson, Lauren C. Blekkenhorst, Jonathan M. Hodgson, Joshua R. Lewis, Mandy Stanley Jan 2022

Psychological Distress And Quality Of Life In Asymptomatic Adults Following Provision Of Imaging Results For Prevention Of Cardiovascular Disease Events: A Scoping Review, Reindolf Anokye, Ben Jackson, James Dimmock, Joanne M. Dickson, Lauren C. Blekkenhorst, Jonathan M. Hodgson, Joshua R. Lewis, Mandy Stanley

Research outputs 2022 to 2026

Aims Psychological distress and changes in health-related quality of life (HRQoL) may occur after screening for disease. Reporting outcomes related to potential benefits and harms of screening is a key recommendation in the guidelines for reporting high-quality trials or interventions. However, no reviews have directly investigated outcomes related to psychological distress and/or changes in HRQoL following imaging assessment of cardiovascular risk and communication of cardiovascular findings to asymptomatic adults. A scoping review was conducted to map research on psychological distress and/or HRQoL following screening. Methods and results

Six electronic databases (MEDLINE, PsychINFO, Social Work Abstracts, Psychology and Behavioural Sciences Collection, …


Determinants Of Switching Intention In The Electricity Markets - An Integrated Structural Model Approach, Shahid Hussain, Pi-Shen Seet, Maria Ryan, Mohammad Iranmanesh, Helen Cripps, Abdul Salam Jan 2022

Determinants Of Switching Intention In The Electricity Markets - An Integrated Structural Model Approach, Shahid Hussain, Pi-Shen Seet, Maria Ryan, Mohammad Iranmanesh, Helen Cripps, Abdul Salam

Research outputs 2022 to 2026

This study adopts an integrated approach and combines the theory of planned behavior and push-pull theory to unpack the antecedents of customer switching intention in a contextual setting (Western Australia) that has a regulated electricity market. Partial least squares structural equation modeling was used to analyze data from a survey of 405 retail electricity consumers, which reveals that perceived relative price, electronic word-of-mouth, customer-based reputation of a service provider, past switching experience, and subjective norms significantly influence attitude toward switching and switching intention. Our findings contribute to the literature on retail electricity markets by showing the importance of customer-based reputation …


Ancestral Sars-Cov-2, But Not Omicron, Replicates Less Efficiently In Primary Pediatric Nasal Epithelial Cells, Yanshan Zhu, Keng Yih Chew, Melanie Wu, Anjana C. Karawita, Georgina Mccallum, Lauren E. Steele, Ayaho Yamamoto, Larisa I. Labzin, Tejasri Yarlagadda, Alexander A. Khromykh, Xiaohui Wang, Julian D. J. Sng, Claudia J. Stocks, Yao Xia, Tobias R. Kollmann, David Martino, Merja Joensuu, Frédéric A. Meunier, Giuseppe Balistreri, Helle Bielefeldt-Ohmann, Asha C. Bowen, Anthony Kicic, Peter D. Sly, Kirsten M. Spann, Kirsty R. Short Jan 2022

Ancestral Sars-Cov-2, But Not Omicron, Replicates Less Efficiently In Primary Pediatric Nasal Epithelial Cells, Yanshan Zhu, Keng Yih Chew, Melanie Wu, Anjana C. Karawita, Georgina Mccallum, Lauren E. Steele, Ayaho Yamamoto, Larisa I. Labzin, Tejasri Yarlagadda, Alexander A. Khromykh, Xiaohui Wang, Julian D. J. Sng, Claudia J. Stocks, Yao Xia, Tobias R. Kollmann, David Martino, Merja Joensuu, Frédéric A. Meunier, Giuseppe Balistreri, Helle Bielefeldt-Ohmann, Asha C. Bowen, Anthony Kicic, Peter D. Sly, Kirsten M. Spann, Kirsty R. Short

Research outputs 2022 to 2026

Children typically experience more mild symptoms of Coronavirus Disease 2019 (COVID-19) when compared to adults. There is a strong body of evidence that children are also less susceptible to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection with the ancestral viral isolate. However, the emergence of SARS-CoV-2 variants of concern (VOCs) has been associated with an increased number of pediatric infections. Whether this is the result of widespread adult vaccination or fundamental changes in the biology of SARS-CoV-2 remain to be determined. Here, we use primary nasal epithelial cells (NECs) from children and adults, differentiated at an air-liquid interface to …


Bioturbation By Echidna (Tachyglossus Aculeatus) In A Forest Habitat, South-Western Australia, Shannon J. Dundas, Lara Osborne, Anna J. M. Hopkins, Katinka X. Ruthrof, Patricia A. Fleming Jan 2022

Bioturbation By Echidna (Tachyglossus Aculeatus) In A Forest Habitat, South-Western Australia, Shannon J. Dundas, Lara Osborne, Anna J. M. Hopkins, Katinka X. Ruthrof, Patricia A. Fleming

Research outputs 2022 to 2026

Bioturbation by digging animals is important for key forest ecosystem processes such as soil turnover, decomposition, nutrient cycling, water infiltration, seedling recruitment, and fungal dispersal. Despite their widespread geographic range, little is known about the role of the short-beaked echidna (Tachyglossus aculeatus) in forest ecosystems. We measured the density and size of echidna diggings in the Northern Jarrah Forest, south-western Australia, to quantify the contribution echidna make to soil turnover. We recorded an overall density of 298 echidna diggings per hectare, 21 % of which were estimated to be less than 1 month old. The average size of digs was …


Bridging The Gap Between Clinical Service And Academic Education Of Hand-Splinting Practice: Perspectives And Experiences Of Thai Occupational Therapists, Anuchart Kaunnil, Veerawat Sansri, Surachart Thongchoomsin, Kannika Permpoonputtana, Mandy Stanley, Piyawat Trevittaya, Chirathip Thawisuk, Peeradech Thichanpiang Jan 2022

Bridging The Gap Between Clinical Service And Academic Education Of Hand-Splinting Practice: Perspectives And Experiences Of Thai Occupational Therapists, Anuchart Kaunnil, Veerawat Sansri, Surachart Thongchoomsin, Kannika Permpoonputtana, Mandy Stanley, Piyawat Trevittaya, Chirathip Thawisuk, Peeradech Thichanpiang

Research outputs 2022 to 2026

A gap in knowledge about current splinting practice exists between the educational program and clinical service. To bridge this gap, we investigated the perspectives and experiences of Thai occupational therapists regarding contemporary hand splinting practices in clinical use. A mixed-method study was designed. An explanatory sequential mixed methods design was used. In the first quantitative phase, a survey questionnaire was mailed to occupational therapists. The questions were regarding contemporary hand splinting practices in clinical use at seven hospitals in the capital city of Bangkok and outskirt areas. In the second phase, semi-structured interviews were completed to explore expert occupational therapists' …


Comparison Of The Cardiometabolic Profiles Of Adolescents Conceived Through Art With Those Of A Non-Art Cohort, L. A. Wijs, D. A. Doherty, J. A. Keelan, P. Burton, J. L. Yovich, L. Beilin, T. A. Mori, R. C. Huang, L. A. Adams, John K. Olynyk, O. T. Ayonrinde, B. Penova-Veselinovic, R. J. Hart Jan 2022

Comparison Of The Cardiometabolic Profiles Of Adolescents Conceived Through Art With Those Of A Non-Art Cohort, L. A. Wijs, D. A. Doherty, J. A. Keelan, P. Burton, J. L. Yovich, L. Beilin, T. A. Mori, R. C. Huang, L. A. Adams, John K. Olynyk, O. T. Ayonrinde, B. Penova-Veselinovic, R. J. Hart

Research outputs 2022 to 2026

STUDY QUESTION: Is the cardiometabolic health of adolescents conceived through ART worse than that of their counterparts conceived without ART? SUMMARY ANSWER: The majority of cardiometabolic and vascular health parameters of adolescents conceived through ART are similar or more favourable, than those of their counterparts of similar age and conceived without ART. WHAT IS KNOWN ALREADY: It has been proposed that the cardiometabolic health of offspring conceived with ART may be unfavourable compared to that of their counterparts conceived without ART. The literature pertaining to cardiometabolic health of offspring conceived after ART is contradictory, but generally suggests unfavourable cardiometabolic health …


Editorial: Fire Regimes In Desert Ecosystems: Drivers, Impacts And Changes, Eddie J. B. Van Etten, Matthew L. Brooks, Aaron C. Greenville, Glenda M. Wardle Jan 2022

Editorial: Fire Regimes In Desert Ecosystems: Drivers, Impacts And Changes, Eddie J. B. Van Etten, Matthew L. Brooks, Aaron C. Greenville, Glenda M. Wardle

Research outputs 2022 to 2026

Although not commonly associated with fire, many desert ecosystems across the globe do occasionally burn, and there is evidence that fire incidences are increasing, leading to altered fire regimes in this biome. The increased prevalence of megafires (wildfires > 10,000 ha in size and typically damaging) in most global biomes is linked to climate change, although those occurring in deserts have received far less attention, from both a research and policy perspective, than that of forested ecosystems (Linley et al., 2022). Understanding the drivers of desert fires, from climate to landscape patterns of hydrology and soil, and how these may be …


Flavonoid Intakes Inversely Associate With Copd In Smokers, Nicola P. Bondonno, Benjamin H. Parmenter, Frederik Dalgaard, Kevin Murray, Daniel Bech Rasmussen, Cecilie Kyrø, Aedin Cassidy, Catherine P. Bondonno, Joshua R. Lewis, Kevin D. Croft, Gunnar Gislason, Augustin Scalbert, Anne Tjønneland, Kim Overvad, Anja Olsen, Jonathan M. Hodgson Jan 2022

Flavonoid Intakes Inversely Associate With Copd In Smokers, Nicola P. Bondonno, Benjamin H. Parmenter, Frederik Dalgaard, Kevin Murray, Daniel Bech Rasmussen, Cecilie Kyrø, Aedin Cassidy, Catherine P. Bondonno, Joshua R. Lewis, Kevin D. Croft, Gunnar Gislason, Augustin Scalbert, Anne Tjønneland, Kim Overvad, Anja Olsen, Jonathan M. Hodgson

Research outputs 2022 to 2026

Introduction: Higher flavonoid intakes are beneficially associated with pulmonary function parameters; however, their association with chronic obstructive pulmonary disease (COPD) is unknown. This study aimed to examine associations between intakes of 1) total flavonoids, 2) flavonoid subclasses and 3) major flavonoid compounds with incident COPD in participants from the Danish Diet, Cancer and Health study. Methods: This prospective cohort included 55 413 men and women without COPD, aged 50-65 years at recruitment. Habitual flavonoid intakes at baseline were estimated from a food frequency questionnaire using Phenol-Explorer. Danish nationwide registers were used to identify incident cases of COPD. Associations were modelled …


Lacking Clarity Or Strategic Ambiguity? Comment On “Competing Frames In Global Health Governance: An Analysis Of Stakeholder Influence On The Political Declaration On Non-Communicable Diseases”, Angela Carriedo, Kathrin Lauber, Margaret M. Miller, Rob Ralston Jan 2022

Lacking Clarity Or Strategic Ambiguity? Comment On “Competing Frames In Global Health Governance: An Analysis Of Stakeholder Influence On The Political Declaration On Non-Communicable Diseases”, Angela Carriedo, Kathrin Lauber, Margaret M. Miller, Rob Ralston

Research outputs 2022 to 2026

This commentary engages with Suzuki and colleagues’ analysis about the ambiguity of multi-stakeholder discourses in the United Nations (UN) Political Declaration of the 3rd High-Level Meeting of the General Assembly on the Prevention and Control of Non-Communicable Diseases (HLM-NCDs), suggesting that blurring between public and private sector in this declaration reflects broader debates about multi-stakeholder partnerships (MSPs) and public-private partnerships (PPPs) in health governance. We argue that the ambiguity between the roles and responsibilities of public and private actors involved may downplay the role (and regulation) of conflicts of interest (COI) between unhealthy commodity industries and public health. We argue …


European Epidemiological Patterns Of Cannabis- And Substance-Related Congenital Cardiovascular Anomalies: Geospatiotemporal And Causal Inferential Study, Albert Stuart Reece, Gary Kenneth Hulse Jan 2022

European Epidemiological Patterns Of Cannabis- And Substance-Related Congenital Cardiovascular Anomalies: Geospatiotemporal And Causal Inferential Study, Albert Stuart Reece, Gary Kenneth Hulse

Research outputs 2022 to 2026

As prenatal and community cannabis exposures have recently been linked with congenital heart disease (CHD), it was of interest to explore these associations in Europe in a causal framework and space-time context. Congenital anomaly data from Eurocat, drug-use data from the European Monitoring Centre for Drugs and Drug Addiction, and income from the World Bank. Countries with rising daily cannabis use had in general higher congenital anomaly rates over time than those without (time: status interaction: β-Est. = 0.0267, P = 0.0059). At inverse probability-weighted panel regression, cannabis terms were positive and significant for CHD, severe CHD, atrial septal defect, …


Protective Factors Against Self-Harm And Suicidality Among Australian Indigenous Adolescents: A Strengths-Based Analysis Of The Longitudinal Study Of Indigenous Children, Irteja Islam, Lisa Sharwood, Verity Chadwick, Tuguy Esgin, Alexandra Martiniuk Jan 2022

Protective Factors Against Self-Harm And Suicidality Among Australian Indigenous Adolescents: A Strengths-Based Analysis Of The Longitudinal Study Of Indigenous Children, Irteja Islam, Lisa Sharwood, Verity Chadwick, Tuguy Esgin, Alexandra Martiniuk

Research outputs 2022 to 2026

Background: Understanding and encouraging social and emotional well-being (SEWB) among Indigenous adolescents is vital in countering the impacts of colonisation and intergenerational trauma. As self-harm and suicidality are considered markers of poor SEWB among Indigenous communities, we aimed to identify the individual-level and community-level factors protecting Indigenous adolescents from self-harm and suicidality. Methods: Data came from Footprints in Time—The Longitudinal Study of Indigenous Children (waves 10 and 11), conducted among Indigenous families across Australia. A strengths-based analysis fitted multilevel logistic regression to explore associations with factors proposed as protective against self-reported self-harm and suicidality among Indigenous adolescents. Results: Our study …


Dosage, Intensity, And Frequency Of Language Therapy For Aphasia: A Systematic Review-Based, Individual Participant Data Network Meta-Analysis, The Rehabilitation And Recovery Of People With Aphasia After Stroke (Release) Collaborators Jan 2022

Dosage, Intensity, And Frequency Of Language Therapy For Aphasia: A Systematic Review-Based, Individual Participant Data Network Meta-Analysis, The Rehabilitation And Recovery Of People With Aphasia After Stroke (Release) Collaborators

Research outputs 2022 to 2026

Background and Purpose: Optimizing speech and language therapy (SLT) regimens for maximal aphasia recovery is a clinical research priority. We examined associations between SLT intensity (hours/week), dosage (total hours), frequency (days/week), duration (weeks), delivery (face to face, computer supported, individual tailoring, and home practice), content, and language outcomes for people with aphasia.

Methods: Databases including MEDLINE and Embase were searched (inception to September 2015). Published, unpublished, and emerging trials including SLT and ≥ 10 individual participant data on aphasia, language outcomes, and time post-onset were selected. Patient-level data on stroke, language, SLT, and trial risk of bias were independently extracted. …


Designing And Using Innovative Learning Spaces: What Teachers Have To Say, Julia E. Morris, Wesley Imms Jan 2022

Designing And Using Innovative Learning Spaces: What Teachers Have To Say, Julia E. Morris, Wesley Imms

Research outputs 2022 to 2026

There is no universal definition of what constitutes an innovative learning environment, because each school is unique. Plans to Pedagogy, developed by the University of Melbourne’s Learning Environments Applied Research Network (LEaRN) team, is exploring issues schools identify as they transition to and use innovative learning environments. Embedded in a range of schools across Australia and New Zealand, each school is assigned an academic who works with them to co-design a project targeting the school’s identified spatial challenge. This paper overviews the eight current Plans to Pedagogy projects to give a sense of the issues faced by teachers in terms …


Prevalence And Risk Factors Of Preterm Birth Among Pregnant Women Admitted At The Labor Ward Of The Komfo Anokye Teaching Hospital, Ghana, Enoch Odame Anto, Wina Ivy Ofori Boadu, Stephen Opoku, Ebenzer Senu, Valentine Christian Kodzo Tsatsu Tamakloe, Augustine Tawiah, Frank Ankobea, Emmanuel Acheampong, Agartha Odame Anto, Michael Appiah, Yaw Amo Wiafe, Max Efui Annani-Akollor, Christian Obirikorang, Otchere Addai-Mensah Jan 2022

Prevalence And Risk Factors Of Preterm Birth Among Pregnant Women Admitted At The Labor Ward Of The Komfo Anokye Teaching Hospital, Ghana, Enoch Odame Anto, Wina Ivy Ofori Boadu, Stephen Opoku, Ebenzer Senu, Valentine Christian Kodzo Tsatsu Tamakloe, Augustine Tawiah, Frank Ankobea, Emmanuel Acheampong, Agartha Odame Anto, Michael Appiah, Yaw Amo Wiafe, Max Efui Annani-Akollor, Christian Obirikorang, Otchere Addai-Mensah

Research outputs 2022 to 2026

Preterm birth is a global epidemic and a leading cause of neonatal mortality in Sub-Saharan Africa. We evaluated the prevalence and risk factors of preterm birth among women attending the labor ward for delivery at a tertiary hospital in Ghana. This comparative cross-sectional study was conducted among a cohort of 209 pregnant women admitted to the labor ward of the Komfo Anokye Teaching Hospital (KATH). Pregnant women who delivered between 28 and 36 completed weeks of gestation were classified as preterm delivery whereas those who delivered after 37–42 completed weeks were described as term. Sociodemographic, clinical, and obstetric data were …


Validation Of The Multi-Dimensional Student Perceptions Of School Questionnaire (Mspsq): Early Findings And Next Steps, Mary-Anne Macdonald, Eyal Gringart Jan 2022

Validation Of The Multi-Dimensional Student Perceptions Of School Questionnaire (Mspsq): Early Findings And Next Steps, Mary-Anne Macdonald, Eyal Gringart

Research outputs 2022 to 2026

Research in Indigenous and non-Indigenous education in Australia over the last two decades has begun to turn towards quantitative methods of understanding various factors affecting student outcomes. The current article presents a new measurement instrument, the Multi-Dimensional Student Perceptions of School Questionnaire (MSPSQ), validated with a moderate-sized sample of secondary students in Western Australia (Indigenous: n = 244; non-Indigenous: n = 258; not stated: n = 34). The MSPSQ aimed to measure student perceptions of select experiences within the family, community and school which may factor in school engagement and beliefs regarding normative education behaviour and likely outcomes. Exploratory factor …


Evaluation Of Virtual Screening Strategies For The Identification Of Γ-Secretase Inhibitors And Modulators, Alicia Ioppolo, Melissa Eccles, David Groth, Giuseppe Verdile, Mark Agostino Jan 2022

Evaluation Of Virtual Screening Strategies For The Identification Of Γ-Secretase Inhibitors And Modulators, Alicia Ioppolo, Melissa Eccles, David Groth, Giuseppe Verdile, Mark Agostino

Research outputs 2022 to 2026

γ-Secretase is an intramembrane aspartyl protease that is important in regulating normal cell physiology via cleavage of over 100 transmembrane proteins, including Amyloid Precursor Protein (APP) and Notch family receptors. However, aberrant proteolysis of substrates has implications in the progression of disease pathologies, including Alzheimer’s disease (AD), cancers, and skin disorders. While several γ-secretase inhibitors have been identified, there has been toxicity observed in clinical trials associated with non-selective enzyme inhibition. To address this, γ-secretase modulators have been identified and pursued as more selective agents. Recent structural evidence has provided an insight into how γ-secretase inhibitors and modulators are recognized …


Residual Renal Function – How Fast Does The Residual Urine Output Function Decline In The First Year Of Haemodialysis? – A Scoping Review, Ulrich Steinwandel, Homa Kheirkhah, Hugh Davies Jan 2022

Residual Renal Function – How Fast Does The Residual Urine Output Function Decline In The First Year Of Haemodialysis? – A Scoping Review, Ulrich Steinwandel, Homa Kheirkhah, Hugh Davies

Research outputs 2022 to 2026

Background: Haemodialysis is the most common treatment method in Australia for individuals requiring renal replacement therapy. Although it is known that the residual renal function in these patients has many advantages for their overall health outcomes and that the residual urine volume production is also declining over time, it is unknown how fast this functional decline occurs when patients are embarking on their first year on haemodialysis. Aim: This scoping review sought to determine if the functional decline in renal residual function in the first year of haemodialysis has been previously investigated, documented or quantified. Method: The scoping review was …


Changes In Body Composition In Patients With Malignant Pleural Mesothelioma And The Relationship With Activity Levels And Dietary Intake, Emily Jeffery, Y. C. Gary Lee, Robert U. Newton, Philippa Lyons-Wall, Joanne Mcveigh, Deirdre B. Fitzgerald, Leon Straker, Carolyn J. Peddle-Mcintyre Jan 2022

Changes In Body Composition In Patients With Malignant Pleural Mesothelioma And The Relationship With Activity Levels And Dietary Intake, Emily Jeffery, Y. C. Gary Lee, Robert U. Newton, Philippa Lyons-Wall, Joanne Mcveigh, Deirdre B. Fitzgerald, Leon Straker, Carolyn J. Peddle-Mcintyre

Research outputs 2022 to 2026

Background:

Skeletal muscle loss is common in advanced cancer and is associated with negative outcomes. In malignant pleural mesothelioma (MPM), no study has reported body composition changes or factors associated with these changes. This study aimed to describe changes in body composition over time and its relationship with activity levels, dietary intake and survival.

Methods:

The study was a secondary analysis of data collected from a longitudinal observational study of patients with MPM. Participants completed 3-month assessments for up to 18 months. Participants with two dual-energy x-ray absorptiometry (DXA) scans were included. Changes in appendicular skeletal muscle mass (ASM) and …


Understanding Employee Travel Behaviours In Response To Workplace Relocation: A Case Study Comparing Commuting Patterns Between Subiaco And Perth, Western Australia, Emil E. Jonescu, Chamil E. Ramanayaka, Stephen Moorcroft, Dean Symington Jan 2022

Understanding Employee Travel Behaviours In Response To Workplace Relocation: A Case Study Comparing Commuting Patterns Between Subiaco And Perth, Western Australia, Emil E. Jonescu, Chamil E. Ramanayaka, Stephen Moorcroft, Dean Symington

Research outputs 2022 to 2026

Our built environments offer distinct variables that impact behaviour–throughout the world, and equally within Western Australia. However, an in-depth analysis of extant literature indicates that influencing human behaviour is difficult in the absence of a ‘disruption’ event. Accordingly, this organization-level study examined the disruptive effects of relocating from a Subiaco office to a new office in Perth’s Central Business District on the commute habits of its built-environment professional employees. The relocation occurred during a ‘non-lockdown’ period between July and August 2021 (southern hemisphere winter). The study sought to determine if an office relocation constituted a sufficient ‘disruption’ to affect employees’ …