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Research outputs 2022 to 2026

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Flipped Classroom In Business And Entrepreneurship Education: A Systematic Review And Future Research Agenda, Madugoda Gunaratnege Senali, Mohammad Iranmanesh, Morteza Ghobakhloo, Denise Gengatharen, Ming Lang Tseng, Mehrbakhsh Nilsashi Mar 2022

Flipped Classroom In Business And Entrepreneurship Education: A Systematic Review And Future Research Agenda, Madugoda Gunaratnege Senali, Mohammad Iranmanesh, Morteza Ghobakhloo, Denise Gengatharen, Ming Lang Tseng, Mehrbakhsh Nilsashi

Research outputs 2022 to 2026

Flipped learning environments have found their way into business and entrepreneurship education. While most studies have found that flipped classrooms can enhance learning effectiveness, the instructors still struggle to implement flipped courses effectively. The instructors' and learners' low understanding of flipped learning benefits, in-class and out-of-class activities, its implementation challenges, and troubleshooting strategies are the issues that influence the implementation of the flipped classrooms. This article aims to enhance the understanding of these issues, especially to those new to the flipped classroom approach, by synthesising the current knowledge on the approach in business and entrepreneurship education using a systematic review …


Attenuated Lower Limb Stretch-Shorten-Cycle Capacity In Acl Injured Vs. Non-Injured Female Alpine Ski Racers: Not Just A Matter Of Between-Limb Asymmetry, Matthew J. Jordan, Nathaniel Morris, Sophia Nimphius, Per Aagaard, Walter Herzog Mar 2022

Attenuated Lower Limb Stretch-Shorten-Cycle Capacity In Acl Injured Vs. Non-Injured Female Alpine Ski Racers: Not Just A Matter Of Between-Limb Asymmetry, Matthew J. Jordan, Nathaniel Morris, Sophia Nimphius, Per Aagaard, Walter Herzog

Research outputs 2022 to 2026

A retrospective analysis of routine countermovement jump (CMJ) testing, a coupled eccentric-concentric (stretch-shorten-cycle: SSC) movement, was performed in female elite alpine skiers with anterior cruciate ligament (ACL) reconstruction (ACLR) and without ACLR. A total of 567 tests obtained from the daily training environment were analyzed in 41 elite female athletes (non-injured control: n = 30, ACLR: n = 17), including n = 6 athletes with pre-injury data, between 16 and 32 years of age from alpine ski racing (n = 32) and skier cross (n = 9). Bilateral CMJ testing was conducted on a dual force plate system, and the …


Coal Fines Migration: A Holistic Review Of Influencing Factors, Faisal Ur Rahman Awan, Muhammad Arif, Stefan Iglauer, Alireza Keshavarz Mar 2022

Coal Fines Migration: A Holistic Review Of Influencing Factors, Faisal Ur Rahman Awan, Muhammad Arif, Stefan Iglauer, Alireza Keshavarz

Research outputs 2022 to 2026

Coal fines can substantially influence coal seam gas reservoir permeability, thus impeding the flow of gas in coal microstructure. The coal fines generation and migration are influenced by several factors, wherein coal fines are generally hydrophobic and aggregate in natural coal seam gas (CSG) under prevailing conditions of pH, salinity, temperature and pressure. This aggregation behaviour can damage the coal matrix and cleat system permeabilities, leading to a considerable reduction of proppant pack conductivity (i.e. fracture conductivity). Several datasets have been reported within the literature on this subject in the last decade. However, a more up-to-date discussion of this area …


Geotemporospatial And Causal Inferential Epidemiological Overview And Survey Of Usa Cannabis, Cannabidiol And Cannabinoid Genotoxicity Expressed In Cancer Incidence 2003–2017: Part 3 – Spatiotemporal, Multivariable And Causal Inferential Pathfinding And Exploratory Analyses Of Prostate And Ovarian Cancers, Albert Stuart Reece, Gary Kenneth Hulse Mar 2022

Geotemporospatial And Causal Inferential Epidemiological Overview And Survey Of Usa Cannabis, Cannabidiol And Cannabinoid Genotoxicity Expressed In Cancer Incidence 2003–2017: Part 3 – Spatiotemporal, Multivariable And Causal Inferential Pathfinding And Exploratory Analyses Of Prostate And Ovarian Cancers, Albert Stuart Reece, Gary Kenneth Hulse

Research outputs 2022 to 2026

Background: The epidemiology of cannabinoid-related cancerogenesis has not been studied with cutting edge epidemiological techniques. Building on earlier bivariate papers in this series we aimed to conduct pathfinding studies to address this gap in two tumours of the reproductive tract, prostate and ovarian cancer. Methods: Age-standardized cancer incidence data for 28 tumour types (including “All (non-skin) Cancer”) was sourced from Centres for Disease Control and National Cancer Institute using SEER*Stat software across US states 2001–2017. Drug exposure was sourced from the nationally representative household survey National Survey of Drug Use and Health conducted annually by the Substance Abuse and Mental …


Geotemporospatial And Causal Inferential Epidemiological Overview And Survey Of Usa Cannabis, Cannabidiol And Cannabinoid Genotoxicity Expressed In Cancer Incidence 2003–2017: Part 2 – Categorical Bivariate Analysis And Attributable Fractions, Albert Stuart Reece, Gary Kenneth Hulse Mar 2022

Geotemporospatial And Causal Inferential Epidemiological Overview And Survey Of Usa Cannabis, Cannabidiol And Cannabinoid Genotoxicity Expressed In Cancer Incidence 2003–2017: Part 2 – Categorical Bivariate Analysis And Attributable Fractions, Albert Stuart Reece, Gary Kenneth Hulse

Research outputs 2022 to 2026

Background: As the cannabis-cancer relationship remains an important open question epidemiological investigation is warranted to calculate key metrics including Rate Ratios (RR), Attributable Fractions in the Exposed (AFE) and Population Attributable Risks (PAR) to directly compare the implicated case burden between emerging cannabinoids and the established carcinogen tobacco. Methods: SEER*Stat software from Centres for Disease Control was used to access age-standardized state census incidence of 28 cancer types (including “All (non-skin) Cancer”) from National Cancer Institute in US states 2001–2017. Drug exposures taken from the National Survey of Drug Use and Health 2003–2017, response rate 74.1%. Federal seizure data provided …


Geotemporospatial And Causal Inferential Epidemiological Overview And Survey Of Usa Cannabis, Cannabidiol And Cannabinoid Genotoxicity Expressed In Cancer Incidence 2003–2017: Part 1 - Continuous Bivariate Analysis, Albert Stuart Reece, Gary Kenneth Hulse Mar 2022

Geotemporospatial And Causal Inferential Epidemiological Overview And Survey Of Usa Cannabis, Cannabidiol And Cannabinoid Genotoxicity Expressed In Cancer Incidence 2003–2017: Part 1 - Continuous Bivariate Analysis, Albert Stuart Reece, Gary Kenneth Hulse

Research outputs 2022 to 2026

Background

The genotoxic and cancerogenic impacts of population-wide cannabinoid exposure remains an open but highly salient question. The present report examines these issues from a continuous bivariate perspective with subsequent reports continuing categorical and detailed analyses.

Methods

Age-standardized state census incidence of 28 cancer types (including “All (non-skin) Cancer”) was sourced using SEER*Stat software from Centres for Disease Control and National Cancer Institute across US states 2001–2017. It was joined with drug exposure data from the nationally representative National Survey of Drug Use and Health conducted annually by the Substance Abuse and Mental Health Services Administration 2003–2017, response rate 74.1%. …


An Investigation Of A Novel Broad Autism Phenotype: Increased Facial Masculinity Among Parents Of Children On The Autism Spectrum, Diana Weiting Tan, Syed Zulqarnain Gilani, Gail A. Alvares, Ajmal Mian, Andrew J. O. Whitehouse, Murray T. Maybery Mar 2022

An Investigation Of A Novel Broad Autism Phenotype: Increased Facial Masculinity Among Parents Of Children On The Autism Spectrum, Diana Weiting Tan, Syed Zulqarnain Gilani, Gail A. Alvares, Ajmal Mian, Andrew J. O. Whitehouse, Murray T. Maybery

Research outputs 2022 to 2026

The broad autism phenotype commonly refers to sub-clinical levels of autistic-like behaviour and cognition presented in biological relatives of autistic people. In a recent study, we reported findings suggesting that the broad autism phenotype may also be expressed in facial morphology, specifically increased facial masculinity. Increased facial masculinity has been reported among autistic children, as well as their non-autistic siblings. The present study builds on our previous findings by investigating the presence of increased facial masculinity among non-autistic parents of autistic children. Using a previously established method, a 'facial masculinity score' and several facial distances were calculated for each three-dimensional …


Hydrogen Flooding Of A Coal Core: Effect On Coal Swelling, Stefan Iglauer, Hamed Akhondzadeh, Hussein Abid, Adriana Paluszny, Alireza Keshavarz, Muhammad Ali, Ausama Giwelli, Lionel Esteban, Joel Sarout, Maxim Lebedev Mar 2022

Hydrogen Flooding Of A Coal Core: Effect On Coal Swelling, Stefan Iglauer, Hamed Akhondzadeh, Hussein Abid, Adriana Paluszny, Alireza Keshavarz, Muhammad Ali, Ausama Giwelli, Lionel Esteban, Joel Sarout, Maxim Lebedev

Research outputs 2022 to 2026

Hydrogen is a clean fuel which has the potential to drastically decarbonize the energy supply chain. However, hydrogen storage is currently a key challenge; one solution to this problem is hydrogen geo-storage, with which very large quantities of H2 can be stored economically. Possible target formations are deep coal seams, and coal permeability is a key parameter which determines how fast H2 can be injected and withdrawn again. However, it is well known that gas injection into coal can lead to coal swelling, which drastically reduces permeability. We thus injected H2 gas into a coal core and measured dynamic permeability, …


The Association Between Alzheimer's Disease-Related Markers And Physical Activity In Cognitively Normal Older Adults, Steve Pedrini, Pratishtha Chatterjee, Akinori Nakamura, Michelle Tegg, Eugene Hone, Stephanie R. Rainey-Smith, Christopher C. Rowe, Vincent Dore, Victor L. Villemagne, David Ames, Naoki Kaneko, Samantha L. Gardener, Kevin Taddei, Binosha Fernando, Ian Martins, Prashant Bharadwaj, Hamid R. Sohrabi, Colin L. Masters, Belinda Brown, Ralph N. Martins, Aibl Research Group Mar 2022

The Association Between Alzheimer's Disease-Related Markers And Physical Activity In Cognitively Normal Older Adults, Steve Pedrini, Pratishtha Chatterjee, Akinori Nakamura, Michelle Tegg, Eugene Hone, Stephanie R. Rainey-Smith, Christopher C. Rowe, Vincent Dore, Victor L. Villemagne, David Ames, Naoki Kaneko, Samantha L. Gardener, Kevin Taddei, Binosha Fernando, Ian Martins, Prashant Bharadwaj, Hamid R. Sohrabi, Colin L. Masters, Belinda Brown, Ralph N. Martins, Aibl Research Group

Research outputs 2022 to 2026

Previous studies have indicated that physical activity may be beneficial in reducing the risk for Alzheimer's disease (AD), although the underlying mechanisms are not fully understood. The goal of this study was to evaluate the relationship between habitual physical activity levels and brain amyloid deposition and AD-related blood biomarkers (i.e., measured using a novel high-performance mass spectrometry-based assay), in apolipoprotein E (APOE) ε4 carriers and noncarriers. We evaluated 143 cognitively normal older adults, all of whom had brain amyloid deposition assessed using positron emission tomography and had their physical activity levels measured using the International Physical Activity Questionnaire (IPAQ). We …


Barriers And Enablers For Older Adults Participating In A Home-Based Pragmatic Exercise Program Delivered And Monitored By Amazon Alexa: A Qualitative Study, Paul Jansons, Jackson Fyfe, Jack Dalla Via, Robin M. Daly, Eugene Gvozdenko, David Scott Mar 2022

Barriers And Enablers For Older Adults Participating In A Home-Based Pragmatic Exercise Program Delivered And Monitored By Amazon Alexa: A Qualitative Study, Paul Jansons, Jackson Fyfe, Jack Dalla Via, Robin M. Daly, Eugene Gvozdenko, David Scott

Research outputs 2022 to 2026

Background: The remote delivery and monitoring of individually-tailored exercise programs using voice-controlled intelligent personal assistants (VIPAs) that support conversation-based interactions may be an acceptable alternative model of digital health delivery for older adults. The aim of this study was to evaluate the enablers and barriers for older adults participating in a home-based exercise program delivered and monitored by VIPAs. Method: This qualitative study used videoconferencing to conduct semi-structured interviews following a 12-week, prospective single-arm pilot study in 15 adults aged 60 to 89 years living alone in the community. All participants were prescribed an individualized, brief (10 min, 2–4 times …


Identifying And Reporting Position-Specific Countermovement Jump Outcome And Phase Characteristics Within Rugby League, John J. Mcmahon, Jason P. Lake, Paul Comfort Mar 2022

Identifying And Reporting Position-Specific Countermovement Jump Outcome And Phase Characteristics Within Rugby League, John J. Mcmahon, Jason P. Lake, Paul Comfort

Research outputs 2022 to 2026

The countermovement jump (CMJ) has been suggested to be an important test of neuromuscular performance for rugby league (RL) players. Identifying force platform-derived CMJ variables that may be more applicable to RL positions (e.g., forwards and backs) has yet to be fully explored in the scientific literature. The aim of this study was to identify RL position-specific CMJ force-time variables. Specifically, we aimed to compare select forcetime variables from the countermovement (i.e., the combination of unweighting and braking) and propulsion phases of the CMJ between the global forwards and backs positional groups. We also aimed to compare typical (i.e., jump …


Congregating As A Social Phenomenon; The Social Glue That Binds, Martin Maccarthy, Ashlee Morgan, Claire Lambert Mar 2022

Congregating As A Social Phenomenon; The Social Glue That Binds, Martin Maccarthy, Ashlee Morgan, Claire Lambert

Research outputs 2022 to 2026

Purpose: This study aims to consolidate and hone existing spectating and crowd theory. This is achieved by marrying socio-cultural ideas and concepts from related disciplines.

Design/methodology/approach: This conceptual review examines what people do when they congregate at an event, and in doing so, answers the question of what they forgo when denied a crowd. Concepts are teased from the literature as to what happens during participatory congregation (in company, in situ), punctuated by relegation without it.

Findings: Related concepts are organised into a typology. The metamodel is the essence of the paper and includes four themes: (1) identity construction, (2) …


Global Evolutionary Dynamics And Resistome Analysis Of Clostridioides Difficile Ribotype 017, Korakrit Imwattana, Papanin Putsathit, Deirdre A. Collins, Teera Leepattarakit, Pattarachai Kiratisin, Thomas V. Riley, Daniel R. Knight Mar 2022

Global Evolutionary Dynamics And Resistome Analysis Of Clostridioides Difficile Ribotype 017, Korakrit Imwattana, Papanin Putsathit, Deirdre A. Collins, Teera Leepattarakit, Pattarachai Kiratisin, Thomas V. Riley, Daniel R. Knight

Research outputs 2022 to 2026

Clostridioides difficile PCR ribotype (RT) 017 ranks among the most successful strains of C. difficile in the world. In the past three decades, it has caused outbreaks on four continents, more than other ‘epidemic’ strains, but our understanding of the genomic epidemiology underpinning the spread of C. difficile RT 017 is limited. Here, we performed high-resolution phylogenomic and Bayesian evolutionary analyses on an updated and more representative dataset of 282 non-clonal C. difficile RT 017 isolates collected worldwide between 1981 and 2019. These analyses place an estimated time of global dissemination between 1953 and 1983 and identified the acquisition of …


The Risk Of Multiple Anthropogenic And Climate Change Threats Must Be Considered For Continental Scale Conservation And Management Of Seagrass Habitat, Kathryn Mcmahon, Kieryn Kilminster, Robert Canto, Chris Roelfsema, Mitchell Lyons, Gary A. Kendrick, Michelle Waycott, James Udy Mar 2022

The Risk Of Multiple Anthropogenic And Climate Change Threats Must Be Considered For Continental Scale Conservation And Management Of Seagrass Habitat, Kathryn Mcmahon, Kieryn Kilminster, Robert Canto, Chris Roelfsema, Mitchell Lyons, Gary A. Kendrick, Michelle Waycott, James Udy

Research outputs 2022 to 2026

Globally marine-terrestrial interfaces are highly impacted due to a range of human pressures. Seagrass habitats exist in the shallow marine waters of this interface, have significant values and are impacted by a range of pressures. Cumulative risk analysis is widely used to identify risk from multiple threats and assist in prioritizing management actions. This study conducted a cumulative risk analysis of seagrass habitat associated with the Australian continent to support management actions. We developed a spatially explicit risk model based on a database of threats to coastal aquatic habitat in Australia, spanning 35,000 km of coastline. Risk hotspots were identified …


Placental Lesions And Differential Expression Of Pro-And Anti-Angiogenic Growth Mediators And Oxidative Dna Damage Marker In Placentae Of Ghanaian Suboptimal And Optimal Health Status Pregnant Women Who Later Developed Preeclampsia, Enoch Odame Anto, David Antony Coall, Emmanuel Akomanin Asiamah, Osei Owusu Afriyie, Otchere Addai-Mensah, Yaw Amo Wiafe, W. K. B. A. Owiredu, Christian Obirikorang, Max Efui Annani-Akollor, Nicholas Akinwale Titiloye, Eric Adua, Emmanuel Acheampong, Evans Asamoah Adu, Stephen Opoku, Agartha Odame Anto, Augustine Tawiah, Youxin Wang, Wei Wang Mar 2022

Placental Lesions And Differential Expression Of Pro-And Anti-Angiogenic Growth Mediators And Oxidative Dna Damage Marker In Placentae Of Ghanaian Suboptimal And Optimal Health Status Pregnant Women Who Later Developed Preeclampsia, Enoch Odame Anto, David Antony Coall, Emmanuel Akomanin Asiamah, Osei Owusu Afriyie, Otchere Addai-Mensah, Yaw Amo Wiafe, W. K. B. A. Owiredu, Christian Obirikorang, Max Efui Annani-Akollor, Nicholas Akinwale Titiloye, Eric Adua, Emmanuel Acheampong, Evans Asamoah Adu, Stephen Opoku, Agartha Odame Anto, Augustine Tawiah, Youxin Wang, Wei Wang

Research outputs 2022 to 2026

Background Angiogenic growth mediators (AGMs) and oxidative stress (OS) both play essential roles in normal placental vascular development and as such, placental alterations in these factors contribute to pre-eclampsia (PE). Suboptimal health status (SHS), an intermediate between health and disease, has been associated with imbalanced AGMs and OS biomarkers. Thus, SHS pregnant women may be at increased risk of developing PE and may present abnormal placental alteration and expression of AGMs and OS compared to optimal health status (OHS) pregnant women. We examined the histopathological morphology, immunohistochemical expression of AGMs antibodies and oxidative DNA damage marker in the placentae of …


A Mixed-Methods Study To Determine The Impact Of Covid-19 On Food Security, Food Access And Supply In Regional Australia For Consumers And Food Supply Stakeholders, Stephanie Louise Godrich, Johnny Lo, Katherine Kent, Flavio Macau, Amanda Devine Mar 2022

A Mixed-Methods Study To Determine The Impact Of Covid-19 On Food Security, Food Access And Supply In Regional Australia For Consumers And Food Supply Stakeholders, Stephanie Louise Godrich, Johnny Lo, Katherine Kent, Flavio Macau, Amanda Devine

Research outputs 2022 to 2026

Background: The COVID-19 pandemic has impacted the Australian food supply through changed consumer purchasing patterns, and potentially, household food security. The aim of this study was to determine the impact of COVID-19 on the prevalence of food insecurity and food supply issues, and perspectives of food supply stakeholders in regional Australia. Methods: A mixed-methods consumer survey and in-depth interviews with food supply stakeholders were conducted in regional Australia, more specifically South West Western Australia between May and July 2020, immediately after the 1st wave of the pandemic. Results: The prevalence of food insecurity was 21% among consumers, and significantly more …


The Therapeutic Effect Of Exogenous Melatonin On Depressive Symptoms: A Systematic Review And Meta-Analysis, Cancan Li, Dandan Ma, Min Li, Tao Wei, Xuan Zhao, Yuanyuan Heng, Delong Ma, Enoch Odame Anto, Yanbo Zhang, Mingyun Niu, Wangxin Zhang Mar 2022

The Therapeutic Effect Of Exogenous Melatonin On Depressive Symptoms: A Systematic Review And Meta-Analysis, Cancan Li, Dandan Ma, Min Li, Tao Wei, Xuan Zhao, Yuanyuan Heng, Delong Ma, Enoch Odame Anto, Yanbo Zhang, Mingyun Niu, Wangxin Zhang

Research outputs 2022 to 2026

Background: Depression-related mortality and morbidity pose growing public health burdens worldwide. Although the therapeutic effect of exogenous melatonin on depression has been investigated, findings remain inconsistent. We conducted this systematic review and meta-analysis to clarify the effectiveness of melatonin in the treatment of depression, including primary and secondary depression symptoms. Methods: We searched the online databases of PubMed, EMBASE, and the Cochrane Library for original studies published up to May 2021. We used STATA 14.0 software to synthesize the results of included studies. To evaluate the effectiveness of melatonin, we calculated the standardized mean differences (SMDs) and 95% confidence intervals …


How A 7-Week Food Literacy Cooking Program Affects Cooking Confidence And Mental Health: Findings Of A Quasi-Experimental Controlled Intervention Trial, Joanna Rees, Shih Ching Fu, Johnny Lo, Ros Sambell, Joshua R. Lewis, Claus T. Christophersen, Matthew F. Byrne, Robert U. Newton, Siobhan Boyle, Amanda Devine Mar 2022

How A 7-Week Food Literacy Cooking Program Affects Cooking Confidence And Mental Health: Findings Of A Quasi-Experimental Controlled Intervention Trial, Joanna Rees, Shih Ching Fu, Johnny Lo, Ros Sambell, Joshua R. Lewis, Claus T. Christophersen, Matthew F. Byrne, Robert U. Newton, Siobhan Boyle, Amanda Devine

Research outputs 2022 to 2026

Obesity and mental health disorders are rising simultaneously with shifting dietary behavior away from home cooking, toward typically nutrition-poor and energy-dense convenience meals. Food literacy strongly influences nutrition choices. Community-based cooking interventions target barriers to healthy eating and facilitate development of food literacy skills, thereby potentially increasing preparation of home-cooked meals and positively influencing health. This study of 657 healthy Australian adults explored the efficacy of a 7-week cooking program in improving cooking confidence, whether this transferred to behavior surrounding food, and/or affected mental health. Significant post-program improvements in cooking confidence and satisfaction (all p < 0.001, (Formula presented.) 1.12 large), ability to change eating habits (p < 0.001) and overcome lifestyle barriers (p = 0.005) were observed for the intervention group but not control. Participation also improved mental and general health (all p < 0.05, (Formula presented.) 0.02 small). No changes were observed for acquisition and consumption of food, or nutrition knowledge in either group. This 7-week cooking program built cooking confidence and improved general and mental health but did not change dietary behavior. To further improve nutrition related behaviors associated with better mental health, more effort is needed to recruit those with below-average nutrition knowledge and interest in cooking.


Morphology Of Mos2 Nanosheets And Its Influence On Water/Oil Interfacial Tension: A Molecular Dynamics Study, Yang Feng, Jirui Hou, Yulong Yang, Shuting Wang, Dongsen Wang, Tingting Cheng, Zhenjiang You Mar 2022

Morphology Of Mos2 Nanosheets And Its Influence On Water/Oil Interfacial Tension: A Molecular Dynamics Study, Yang Feng, Jirui Hou, Yulong Yang, Shuting Wang, Dongsen Wang, Tingting Cheng, Zhenjiang You

Research outputs 2022 to 2026

Plate-shaped nanoparticles exhibit huge potential for a broad range of cutting-edge applications in interfacial-based science and technology, such as enhanced oil recovery in hydrocarbon reservoirs, owing to their remarkable features in superior affinity toward interfaces. Understanding the adsorption behavior of nanosheets (NSs) self-assembled at the water/oil interface (W/O interface) is crucial to elucidate the variation of interfacial tension (IFT) and establish special design criteria for efficient industrial use of NSs. Here we present a molecular dynamics study to reveal the morphology of carbon-chain modified molybdenum disulfide (MoS2) nanosheets. The stress exerted on a nanosheet is analyzed. The simulation …


Leadership Teams Supporting Teacher Wellbeing By Improving The Culture Of An Australian Secondary School, Geoffrey W. Lummis, Julia E. Morris, Catherine Ferguson, Susan Hill, Graeme Lock Mar 2022

Leadership Teams Supporting Teacher Wellbeing By Improving The Culture Of An Australian Secondary School, Geoffrey W. Lummis, Julia E. Morris, Catherine Ferguson, Susan Hill, Graeme Lock

Research outputs 2022 to 2026

This research explored teachers’ experiences of school and their work-related wellbeing, from the perspective that work-related wellbeing is an organisational responsibility. A single case study was enacted in an urban Western Australian secondary school to explore the relationship between school organisational health and teacher wellbeing. A mixed method pre-test phase determined professional growth, professional interaction and role clarity were areas of organisational health that yielded divergent responses from staff. Subsequently, the school’s leadership team implemented interventions to improve these domains, and post-intervention data collection was conducted 18 months later to determine any changes. Qualitative data showed improvements in the professional …


Conventional Therapies Deplete Brain-Infiltrating Adaptive Immune Cells In A Mouse Model Of Group 3 Medulloblastoma Implicating Myeloid Cells As Favorable Immunotherapy Targets, Zahra Abbas, Courtney George, Mathew Ancliffe, Meegan Howlett, Anya C. Jones, Mani Kuchibhotla, Robert J. Wechsler-Reya, Nicholas G. Gottardo, Raelene Endersby Mar 2022

Conventional Therapies Deplete Brain-Infiltrating Adaptive Immune Cells In A Mouse Model Of Group 3 Medulloblastoma Implicating Myeloid Cells As Favorable Immunotherapy Targets, Zahra Abbas, Courtney George, Mathew Ancliffe, Meegan Howlett, Anya C. Jones, Mani Kuchibhotla, Robert J. Wechsler-Reya, Nicholas G. Gottardo, Raelene Endersby

Research outputs 2022 to 2026

Medulloblastoma is the most common childhood brain cancer. Mainstay treatments of radiation and chemotherapy have not changed in decades and new treatment approaches are crucial for the improvement of clinical outcomes. To date, immunotherapies for medulloblastoma have been unsuccessful, and studies investigating the immune microenvironment of the disease and the impact of current therapies are limited. Preclinical models that recapitulate both the disease and immune environment are essential for understanding immune-tumor interactions and to aid the identification of new and effective immunotherapies. Using an immune-competent mouse model of aggressive Myc-driven medulloblastoma, we characterized the brain immune microenvironment and changes induced …


Alcohol Consumption And Cardiovascular Outcomes In Patients With Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study, Malik Janjua, Matthew Knuiman, Mark Divitini, Brendan Mcquillan, John K. Olynyk, Gary P. Jeffrey, Leon A. Adams Mar 2022

Alcohol Consumption And Cardiovascular Outcomes In Patients With Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study, Malik Janjua, Matthew Knuiman, Mark Divitini, Brendan Mcquillan, John K. Olynyk, Gary P. Jeffrey, Leon A. Adams

Research outputs 2022 to 2026

Low-level alcohol consumption is associated with reduced cardiovascular disease (CVD) in the general population. It is unclear whether this association is seen in patients with nonalcoholic fatty liver disease (NAFLD) who have an increased risk of CVD. We examined the association between alcohol consumption and CVD-related outcomes in subjects with NAFLD from a general population cohort. Subjects participating in the 1994-1995 Busselton Health survey underwent clinical and biochemical assessment. NAFLD was identified using the Fatty Liver Index of >60, and alcohol consumption quantified using a validated questionnaire. CVD hospitalizations and death during the ensuing 20 years were ascertained using the …


Development Of 1,2,4-Oxadiazole Antimicrobial Agents To Treat Enteric Pathogens Within The Gastrointestinal Tract, Noel P. Pitcher, Jitendra R. Harjani, Yichao Zhao, Jianwen Jin, Daniel Knight, Lucy Li, Papanin Putsathit, Thomas V. Riley, Glen P. Carter, Jonathan B. Baell Mar 2022

Development Of 1,2,4-Oxadiazole Antimicrobial Agents To Treat Enteric Pathogens Within The Gastrointestinal Tract, Noel P. Pitcher, Jitendra R. Harjani, Yichao Zhao, Jianwen Jin, Daniel Knight, Lucy Li, Papanin Putsathit, Thomas V. Riley, Glen P. Carter, Jonathan B. Baell

Research outputs 2022 to 2026

Colonization of the gastrointestinal (GI) tract with pathogenic bacteria is an important risk factor for the development of certain potentially severe and life-threatening healthcare-associated infections, yet efforts to develop effective decolonization agents have been largely unsuccessful thus far. Herein, we report modification of the 1,2,4-oxadiazole class of antimicrobial compounds with poorly permeable functional groups in order to target bacterial pathogens within the GI tract. We have identified that the quaternary ammonium functionality of analogue 26a results in complete impermeability in Caco-2 cell monolayers while retaining activity against GI pathogens Clostridioides difficile and multidrug-resistant (MDR) Enterococcus faecium. Low compound recovery levels …


Simultaneous Strength-Ductility Enhancement In As-Cast Ti6al4v Alloy By Trace Ce, K. M. Li, Y. J. Liu, X. C. Liu, X. Wu, S. F. Zhou, Laichang Zhang, W. Li, W. C. Zhang Mar 2022

Simultaneous Strength-Ductility Enhancement In As-Cast Ti6al4v Alloy By Trace Ce, K. M. Li, Y. J. Liu, X. C. Liu, X. Wu, S. F. Zhou, Laichang Zhang, W. Li, W. C. Zhang

Research outputs 2022 to 2026

Impurity elements always play a major role in hindering mechanical property improvement in Ti6Al4V, and specifically most of them e.g. O, P, Cl, and S dissolved in the matrix deteriorate the mechanical properties of Ti6Al4V. This work presents a strategy of enhancing the mechanical performance of as-cast Ti6Al4V alloy by adding a small amount of rare earth (i.e. 0.1 wt% Ce), where deleterious elements could be absorbed from the crystalline lattice during solidification process, forming uniformly distributed Ce-rich oxides or precipitates with ∼200 nm in size. The Ce-rich precipitates in turn refine the beta phase lamellae by introducing more nucleation …


Clostridioides Difficile Infection And One Health: An Equine Perspective, Natasza M. R. Hain-Saunders, Daniel R. Knight, Mieghan Bruce, Thomas V. Riley Mar 2022

Clostridioides Difficile Infection And One Health: An Equine Perspective, Natasza M. R. Hain-Saunders, Daniel R. Knight, Mieghan Bruce, Thomas V. Riley

Research outputs 2022 to 2026

Clostridioides (Clostridium) difficile presents a significant health risk to humans and animals. The complexity of the bacterial–host interaction affecting pathogenesis and disease development creates an ongoing challenge for epidemiological studies, control strategies and prevention planning. The recent emergence of human disease caused by strains of C. difficile found in animals adds to mounting evidence that C. difficile infection (CDI) may be a zoonosis. In equine populations, C. difficile is a known cause of diarrhoea and gastrointestinal inflammation, with considerable mortality and morbidity. This has a significant impact on both the well-being of the animal and, in the case of performance …


Electro‐Driven Materials And Processes For Lithium Recovery—A Review, Anna Siekierka, Marek Bryjak, Amir Razmjou, Wojciech Kujawski, Aleksandar N. Nikoloski, Ludovic F. Dumée Mar 2022

Electro‐Driven Materials And Processes For Lithium Recovery—A Review, Anna Siekierka, Marek Bryjak, Amir Razmjou, Wojciech Kujawski, Aleksandar N. Nikoloski, Ludovic F. Dumée

Research outputs 2022 to 2026

The mass production of lithium‐ion batteries and lithium‐rich e‐products that are required for electric vehicles, energy storage devices, and cloud‐connected electronics is driving an unprecedented demand for lithium resources. Current lithium production technologies, in which extraction and purification are typically achieved by hydrometallurgical routes, possess strong environmental impact but are also energy‐intensive and require extensive operational capabilities. The emergence of selective membrane materials and associated electro‐processes offers an avenue to reduce these energy and cost penalties and create more sustainable lithium production approaches. In this review, lithium recovery technologies are discussed considering the origin of the lithium, which can be …


The Role Of Igg N-Galactosylation In Spondyloarthritis, Xiaojia Xu, Lois A. Balmer, Zhixian Chen, Gehendra Mahara, Ling Lin Mar 2022

The Role Of Igg N-Galactosylation In Spondyloarthritis, Xiaojia Xu, Lois A. Balmer, Zhixian Chen, Gehendra Mahara, Ling Lin

Research outputs 2022 to 2026

Spondyloarthritis (SpA) is a group of chronic inflammatory arthritic diseases causing inflammatory back pain and stiffness, leading to irreversible damage of joint and spine, seriously affecting the quality of life. However, the exact pathogenesis of SpA is still unknown, although the blockers of tumor necrosis factor (TNF) are a major therapeutic advance. Of interest is the association between SpA and Immunoglobulin G (IgG) N-glycosylation. IgG N-glycosylation is a process of post-translational modification (PTM) that takes part in regulating anti- and pro-inflammatory effects. A relationship between IgG N-glycosylation and the development of inflammatory arthritic diseases exists, in addition …


Dual Leadership In Chinese Schools Challenges Executive Principalships As Best Fit For 21st Century Educational Development, Christine Cunningham, Wei Zhang, Michelle Striepe, David Rhodes Mar 2022

Dual Leadership In Chinese Schools Challenges Executive Principalships As Best Fit For 21st Century Educational Development, Christine Cunningham, Wei Zhang, Michelle Striepe, David Rhodes

Research outputs 2022 to 2026

This paper examines China's dual leadership model and compares it with the more traditional (western) single leader model. It addresses an important question in educational leadership: whether singular school leadership or a dual leadership is better? It is innovative as it mobilised an international research team to collect data from 115 Chinese school leaders and compare China's dual leadership with faith-based schools in other contexts. Given so much now is written about distributed leadership within and across schools, this paper offers valuable insights, especially for readers interested in the educational leadership practices of a rising global power.


How Do Ethical Consumers Utilize Sharing Economy Platforms As Part Of Their Sustainable Resale Behavior? The Role Of Consumers’ Green Consumption Values, Teck Ming Tan, Hannu Makkonen, Puneet Kaur, Jari Salo Mar 2022

How Do Ethical Consumers Utilize Sharing Economy Platforms As Part Of Their Sustainable Resale Behavior? The Role Of Consumers’ Green Consumption Values, Teck Ming Tan, Hannu Makkonen, Puneet Kaur, Jari Salo

Research outputs 2022 to 2026

Past research has extensively studied the antecedents and consequences of consumers’ green consumption values, as well as the psychological mechanisms that underlie an ethical consumer. Yet a frustrating paradox remains, indicated by the consumers’ intention–behavior gap for their sustainable behavior. To address this gap, the present study focuses on the consumption values that lead to using a sharing economy platform. Our study draws on the theory of consumption values and altruistic–egoistic values, as well as spillover effect psychology, to examine associations between context-specific values, green consumption values, and sustainable resale behavior. By collaborating with a Nordic second-hand peer-to-peer platform brand, …


Quantitative Analysis Of Methodological And Environmental Influences On Survival Of Planted Mangroves In Restoration And Afforestation, Daniel Gorman, Mathew A. Vanderklift, Anna Lafratta Mar 2022

Quantitative Analysis Of Methodological And Environmental Influences On Survival Of Planted Mangroves In Restoration And Afforestation, Daniel Gorman, Mathew A. Vanderklift, Anna Lafratta

Research outputs 2022 to 2026

Mangrove planting has been employed for decades to achieve aims associated with restoration and afforestation. Often, survival of planted mangroves is low. Improving survival might be aided by augmenting the understanding of which planting methods and environmental variables most influence plant survival across a range of contexts. The aim of this study was to provide a global synthesis of the influence of planting methods and background environment on mangrove survival. This was achieved through a global meta-analysis, which compiled published survival rates for the period 1979–2021 and analyzed the influence of decisions about minimum spacing and which life stage to …