Digital Commons Network^™

Validated And Culturally Specific Screening Tools And Early Response Programs For The Detection And Prevention Of Eating Disorders Among First Nations Peoples In Australia: A Scoping Review, Mark John Castro, Zyana Gall, Alana Gall, Hilary Smith, Kanita Kunaratnam

Research outputs 2022 to 2026

Background: Eating disorders (EDs) are complex mental health conditions that can have severe health consequences, exacerbating the overall disease burden and causing significant economic impacts on healthcare systems. Globally, cultural and societal factors influence the presentation and management of these disorders, necessitating culturally specific approaches to screening and prevention. Among First Nations peoples in Australia, the intersection of historical, cultural, and social factors offers both context and strength in addressing EDs, while also presenting distinct challenges in identification and prevention. Objective: This scoping review seeks to map and evaluate existing research on culturally specific and validated screening tools and early …

Exercise Medicine As Adjunct Therapy During Radiation For Cancer Of The Prostate To Improve Treatment Efficacy – Protocol For The Eradicate Study: A Phase Ii Randomised Controlled Trial, Oliver Schumacher, Robert U. Newton, Colin Tang, Raphael Chee, Sjoerd B. Vos, Ronny S. Low, David Joseph, Dennis R. Taaffe, Daniel A. Galvão

Research outputs 2022 to 2026

Background: Tumour hypoxia resulting from inadequate perfusion is common in many solid tumours, including prostate cancer, and constitutes a major limiting factor in radiation therapy that contributes to treatment resistance. Emerging research in preclinical animal models indicates that exercise has the potential to enhance the efficacy of cancer treatment by modulating tumour perfusion and reducing hypoxia; however, evidence from randomised controlled trials is currently lacking. The ‘Exercise medicine as adjunct therapy during RADIation for CAncer of the prostaTE’ (ERADICATE) study is designed to investigate the impact of exercise on treatment response, tumour physiology, and adverse effects of treatment in prostate …

Industry Return Predictability Using Health Policy Uncertainty, Thach Pham, Deepa Bannigidadmath, Robert Powell

Research outputs 2022 to 2026

This paper examines how a change in health policy uncertainty affects US industry returns using monthly data from January 1985 to September 2020. We employ in-sample and out-of-sample analyses, and we find evidence that 25 out of 49 considered industries are predictable during the health crisis periods, including severe acute respiratory syndrome and the ongoing coronavirus pandemic. The out-of-sample tests corroborate the evidence for the in-sample predictability. Furthermore, using a mean–variance utility function-based trading strategy, we observe that investors can use this simple tool for their trading strategies and make profits from 2.99 to 11.44% per annum. Our findings are …

The Significant Impact Of Hot Isostatic Pressing On The Corrosion Behavior Of Ti-6al-4v Alloy Prepared By Electron Beam Powder Bed Fusion, Hongyu Zheng, Yun Bai, Wentao Hou, Zirong Zhai, Lai Chang Zhang, Shujun Li, Rui Yang

Research outputs 2022 to 2026

This work investigated the effect of hot isostatic pressing (HIP) on the corrosion behavior of Ti-6Al-4V samples prepared by electron beam powder bed fusion (EB-PBF). After the HIP treatment, the TiO2 content decreased but the growth rate of passivation films increased, leading to increase in internal defect density, thereby degrading the corrosion resistance. Amongst the different factors impacted by HIP including pore defects, β-phase, texture and morphology of α-phase, the morphology of α-phase played a dominant role in determining the corrosion performance of EB-PBF processed alloy.

Cutting Through The Fog: Recognising Brain Fog As A Significant Public Health Concern, Darren Haywood, Susan L. Rossell, Nicolas H. Hart

Research outputs 2022 to 2026

Brain fog is a highly common condition that can have significant impacts on quality of life and functioning. Most people will experience a condition, illness, or infection that might result in the development of brain fog. We provide a call to action to minimise the impacts of brain fog.

Bio-Inspired Computational Intelligence Metaheuristic-Based Optimization And Sensitivity Analysis Approach To Determine Techno-Economic Feasibility Of Hydrogen Refueling Stations For Fuel Cell Vehicles, Paul C. Okonkwo, Samuel Chukwujindu Nwokolo, Saad S. Alarifi, Stephen E. Ekwok, Rita Orji, Sunday O. Udo, Ahmed M. Eldosouky, El Manaa Barhoumi, Barun Kumar Das, David Gomez-Ortiz, Kamal Abdelrahman, Anthony E. Akpan

Research outputs 2022 to 2026

This study presents a comprehensive economic and technological evaluation of renewable hybrid power systems for hydrogen refueling stations (HRS) in Nizwa, Oman, leveraging cutting-edge optimization algorithms to determine the most cost-effective and efficient hybrid energy system configurations. Three hybrid energy systems of photovoltaic-wind turbine-battery (PV-WT-B), photovoltaic-wind-fuel cell-battery (PV-WT-FC-B), and wind turbine-battery (WT-B) were evaluated based on net present cost (NPC), levelized cost of energy (LCOE), and levelized cost of hydrogen (LCOH). The study employs advanced optimization techniques, including the Mayfly Algorithm, Genetic Algorithm, CUKO Search, Gray Wolf Optimizer (GWO), Constrained Particle Swarm Optimization (CPSO), Harmony Search (HS), and Flower Pollination …

Factors Influencing The Provision Of Human Milk Feeding Support For Preterm Infants In Neonatal Intensive Care Units In China: A Qualitative Study Of Neonatal Nurses’ Perspectives, Wenjie Guo, Haiyan Zhang, Li Wang, Fang Huang, Dongmei Ma, Maggie Zgambo, Sanmei Chen, Yan Wu, Yanmei Bu, Yoko Shimpuku

Research outputs 2022 to 2026

Background: Human milk feeding is crucial for the survival and development of preterm infants, yet their human milk feeding rates at Neonatal Intensive Care Units (NICUs) discharge remain lower than those of healthy newborns. Effective support is essential for improving breast milk feeding outcomes, but remains challenging for NICU nurses. Therefore, this study aimed to examine factors that influence NICU nurses in providing human milk feeding support, including the challenges they face and their needs. Methods: This study employed a qualitative descriptive design. Using maximum variation and purposive sampling, 19 nurses in the NICU were recruited. Between August and September …

Longitudinal Associations Between Maternal And Child Screen Use At 1 Year Of Age And Child Behavior And Development At 3 Years Of Age, Stephanie Sim, Juliana Zabatiero, Natasha Bear, Amber Beynon, George Thomas, Ravisha Srinivasjois, Brad Jongeling, Desiree Silva, Leon Straker

Research outputs 2022 to 2026

Background: Young children are increasingly exposed to evolving screen technology. International guidelines recommend no screen use for children under the age of 2 years, due to the potential for detrimental effects on behaviour and development. However, evidence for these guidelines is limited by inadequate consideration of device-specific effects (TV and mobile phone/tablet computer), maternal screen use, confounders such as maternal mental health and importance of effect sizes. Our aim was to investigate longitudinal associations of device-specific maternal and child technology use and covariates (including maternal mental health) with behavioural and developmental outcomes, to guide adults on screen use behaviours by …

Midwife-Led Birth Debrief: A Concept Analysis, Kate Buchanan, Elliesha O'Reilly, Georgia Wilcox, Sara Bayes, Lauren Kearney, Linda Sweet, Hazel Keedle

Research outputs 2022 to 2026

Background: Psychological birth trauma (PBT) affects approximately 19 % of postnatal women, making its prevention a global priority. Midwives are responsible for providing psychosocial care during the postnatal period to foster the mother-infant relationship, provide education and screening and support positive transitions to parenting. However, the specific attributes of a birth debrief and the role of the midwife in a supporting a woman to review their birth experience is less well documented in regulatory frameworks or scientific literature. This has created significant ambiguity in both clinical practice among health professionals and in research contexts. The lack of a clear understanding …

Periodizing Exercise Medicine Prescription For Patients With Cancer: A Narrative Opinion, Francesco Bettariga, Robert U. Newton, Chris Bishop, Luca Maestroni, Anita Borsati, Alice Avancini, Sara Pilotto, Dennis R. Taaffe, Daniel A. Galvão, G. Gregory Haff

Research outputs 2022 to 2026

Exercise has emerged as an effective therapeutic strategy in cancer management. Long-term supervised exercise programs, including resistance training and aerobic training, can improve body composition and physical fitness, modulate circulating factors (e.g., hormones, cytokines), enhance treatment tolerance, and reduce side effects, potentially influencing cancer progression and reducing mortality risk. Despite advancements in exercise oncology, opportunities remain to refine exercise prescription through the integration of advanced methodologies such as periodization and autoregulatory programming strategies. Periodization, a systematic approach to organizing training over time, has demonstrated benefits in general fitness and clinical populations but is underexplored in cancer care. Emerging evidence suggests …

Relationships Of Upper Respiratory Tract Infections And Holistic Diets And Lifestyles In Northeast China, Hongmei Wang, Khui Hung Lee, Shaoxiao Qin, Kan Yu, Shaoying Hou, Kaihong Tang, Jiabao Liu, Yingyu Jin, Zhuo Shang, Deyu Dai

Research outputs 2022 to 2026

Background: Upper respiratory tract infections (URTIs) are prevalent public health issues worldwide. Their prevention is challenging, and they pose a significant economic burden due to their susceptibility to secondary infections and lack of effective treatments. This study investigates the relationship between URTIs and the holistic diets and lifestyles of residents in Northeast China. Methods: A cross-sectional study was conducted using data from 4058 participants aged 12 to 70 who participated in the Internet-based dietary questionnaire for Chinese (IDQC), collected between 2012 and 2019. Statistical analyses were performed with SPSS 20.0 software, employing chi-square tests for categorical data and Kruskal-Wallis tests …

Teaching Computer-Based Writing: Primary Teachers’ Preparation, Self-Efficacy, And Instructional Practices, Anabela Malpique, Debora Valcan, Deborah Pino-Pasternak, Susan Ledger

Research outputs 2022 to 2026

In the digital age, skilful computer-based writing is essential for school aged children since it empowers them to communicate, acquire knowledge, critically engage with information, and produce text-based original thoughts. However, there is a lack of studies examining teachers’ preparation and self-efficacy for supporting students in developing computer-based writing skills and instructional practices implemented in primary classrooms. In the current study, 340 primary teachers (Grades 1–6) from across Australian states completed a survey about the computer-based writing instruction provided in their classrooms. While results showed that teachers found it was important to teach computer-based writing skills, most respondents reported allocating …

The Use Of Force Plate Technology To Measure Force Production Characteristics In Military Personnel: A Scoping Review Of Methodological Reporting Practices, Peter Ladlow, Kieran M. Lunt, Paul Comfort, Oliver O’Sullivan, Francisco J. Robles-Palazón, Nicholas J. Ripley, John J. Mcmahon, Natalie Masters, Robyn P. Cassidy, Marina De Vecchis, Vanessa Bell, Alexander N. Bennett, Russell J. Coppack

Research outputs 2022 to 2026

Background: Force plates have become one of the most frequently used assessment tools in the field of strength and conditioning research and applied practice. Their use for measuring force production characteristics among military personnel is growing. The aim of this scoping review is to: (1) Describe the current evidence base underpinning the use of force plates to assess maximal and rapid lower-limb force production in military in three priority areas; occupational task performance, injury risk profiling, and rehabilitation, (2) Identify potential trends and/or differences by participants’ sex, job role, and/or level of performance in tests, methodologies, and metrics selected, and …

Therapeutic Potential And Enhanced Bioactivity Of Ficus Carica (Fig) Fruit: Exploring Bioactive Compounds And Nano-Additive Synergies, Mst Sumya Yeasmin, Shamima Abdul Rahman, Waheedah Abdul Hakeem, Tarek Abedin, Mohammad Nur-E-Alam

Research outputs 2022 to 2026

The present investigation deals with the phytochemical, anticancer, antioxidant, anti-inflammatory, antidiabetic, and Anti-constipation activities of Ficus carica (FC) fruit. The phytochemical analysis of FC fruit has revealed a rich array of bioactive compounds, highlighting the fruit's complex and diverse natural chemistry together with some secondary metabolites that contribute to its high antioxidant activity which was evident from 1-Diphenyl-2-picrylhydrazyl (DPPH), 2,2′-Azinobis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) and Ferric reducing power (FRAP) assays. Fruit extracts of FC demonstrated anticancer activity against MCF-7 breast cancer, U2OS osteosarcoma, HepG2 liver cancer, and Huh7it liver cancer cell lines. The anti-inflammatory activity of FC fruit is attributed to steroids …

Interhemispheric Inhibition Modifies Reaction Time Of The Index Finger, Liam C. Tapsell, Christopher Latella, Anthony J. Blazevich, Janet L. Taylor

Research outputs 2022 to 2026

Interhemispheric inhibition (IHI) acts between hemispheres to decrease motor cortical excitability. IHI changes during movement preparation, but it is unknown whether altering IHI, independent of other factors, alters movement initiation. For the index finger abductor muscle (first dorsal interosseous; FDI), IHI is weaker during contralateral index abduction than adduction. Thus, this study aimed to modulate IHI through contralateral contraction and measure resultant changes in reaction time. Fifteen healthy participants (age 19–39 years) completed a reaction-time task requiring brief left index finger abduction. Prior to reactions, participants started either a sustained isometric abduction or adduction contraction of the right index finger. …

A Configurational Approach To Strategic Entrepreneurship: Unlocking Customer Success In New Ventures In Emerging Economies, Sayuri Wijekoon, Mahdi Vesal, Aron O'Cass

Research outputs 2022 to 2026

New ventures (NVs) in emerging economies often face significant challenges in cultivating quality customer relationships and achieving customer satisfaction. This study applies the strategic entrepreneurship framework and configurational theory to investigate how combinations of strategic behaviors, decision-making logics, resource allocation mechanisms, and leader sociocognitive characteristics influence customer-focused performance. Utilizing multi-informant data from 135 NVs (entrepreneurs and marketing managers) in Sri Lanka, our analysis reveals that NVs employing effectual decision-making and bricolage resource allocation achieve stronger alignment between entrepreneurial and market orientations, resulting in enhanced customer satisfaction and stronger relationships. Additionally, the study identifies entrepreneurs’ long-term orientation and managers’ perfectionism as …

Biochar As Additive And Modifier In Bitumen And Asphalt Mixtures, Chathurika Dassanayake, Nuha S. Mashaan

Research outputs 2022 to 2026

Incorporating biochar into pavement materials is a novel and environmentally sustainable approach that aligns with global sustainability goals and advances greener pavement technologies. Studies have shown that biochar significantly enhances the strength, durability, and stability of pavements, while also contributing to sustainability by lowering the carbon footprint associated with traditional construction materials. Additionally, the incorporation of biochar contributes to the sustainability of asphalt engineering by reducing reliance on petroleum-based products and promoting the valorization of biomass. The primary objective of this review is to critically evaluate and synthesize existing research on the use of biochar in bitumen and asphalt mixtures, …

Ceftriaxone Use Evaluation At The Medical Ward, Jigme Dorji Wangchuck National Referral Hospital In Bhutan: A Retrospective Analytical Study, Kezang Tshering, Mongal Singh Gurung, Sonam Wangda, Pelden Chejor

Research outputs 2022 to 2026

Objectives Ceftriaxone is the most commonly prescribed cephalosporin antibiotic in hospital settings. The overall prescribing compliance with the national antibiotic guidelines remained unassessed at Jigme Dorji Wangchuk National Referral Hospital (JDWNRH), Bhutan. Methods A retrospective analytical study was conducted by evaluating the medical records of patients who received ceftriaxone between January and December 2020 in the Medical Ward, JDWNRH. Data were analyzed using the Statistical Package for the Social Sciences, version 26. Results A total of 201 (17.82%) patients, with a mean age of 54.83 years (SD ± 20.93), received ceftriaxone, and pneumonia (49.25%) was the most frequently documented indication. …

Defeating Evasive Malware With Peekaboo: Extracting Authentic Malware Behavior With Dynamic Binary Instrumentation, Matthew Gaber, Mohiuddin Ahmed, Helge Janicke

Research outputs 2022 to 2026

The accuracy of Artificial Intelligence (AI) in malware detection is dependent on the features it is trained with, where the quality and authenticity of these features is dependent on the dataset and the analysis tool. Evasive malware, that alters its behavior in analysis environments, is challenging to extract authentic features from where widely used static and dynamic analysis tools have several limitations. However, Dynamic Binary Instrumentation (DBI) allows deep and precise control of the malware sample, thereby facilitating the extraction of authentic behavior from evasive malware. Considering the limitations of malware analysis for use with AI, this research had two …

Determinants Of Consumers' Mobile Network Continuance Intention: The Mediating Effects Of Cognitive And Affective Inertia, Fazlul Hoque, Pi Shen Seet, Stephanie Meek, Saalem Sadeque

Research outputs 2022 to 2026

Despite extensive research on customer continuance intention, few studies have explored the mediating roles of cognitive and affective inertia in shaping continuance intention, particularly in emerging markets. We address this gap in an empirical study, grounded in the SOR (Stimulus-Organism-Response) framework, that investigates how trust, satisfaction, and switching barriers influence mobile network users' continuance intention, with cognitive and affective inertia as mediators. Using Partial Least Squares Structural Equation Modelling (PLS-SEM), we analyzed primary data from 407 mobile phone users in Bangladesh, an emerging economy. The findings indicate that trust, satisfaction, and switching barriers have a significant influence on continuance intention. …

Echoes Of The Modern Training Periodization Concepts In Russia Before The October 1917 Revolution, Sandro Bartolomei, Gulnara Mammadova, Renato Manno, Gregory G. Haff, Jay R. Hoffman, Franco Merni

Research outputs 2022 to 2026

Abstract – Bartolomei, S, Mammadova, G, Manno, R, Haff, GG, Hoffman, JR, and Merni, F. Echoes of the modern training periodization concepts in Russia before the October 1917 revolution. J Strength Cond Res 39(12): 1327–1330, 2025—The debate on the origins of the discipline of training periodization is still ongoing. The text “Olympic Sport, ” published by B. A. Kotov in 1916, was one of the first known books to focus on training methods and strategies for performance development. The book is also considered the first to deal with training organization and periodization. In addition, Kotov was the only author to …

Hypophosphatemia Across The Lifespan, Madhuni Herath, Richard Prince, Craig F. Munns, Albert Kim

Research outputs 2022 to 2026

No abstract provided.

Imbalances In Circulating Monocyte And High-Density Lipoprotein Cholesterol Exacerbates The Residual Risk Of Incident Myocardial Infarction Beyond Ldl-C: A Real-Life, Prospective Cohort Study, Dan Wu, Yulong Lan, Xiong Ding, Lois Balmer, Xingang Li, Wei Wang, Shouling Wu, Youren Chen

Research outputs 2022 to 2026

Background: A sustained oversupply of monocytes and markedly decreased levels of high-density lipoprotein cholesterol (HDL-C) are notable in high-risk groups with residual cardiovascular risk, despite aggressive low-density lipoprotein cholesterol (LDL-C) lowering. This study aimed to explore whether an imbalance in circulating monocyte and HDL-C levels accounts for the residual risk of incident myocardial infarction (MI) within optimal LDL-C levels. Methods: A total of 48,522 participants free of cardiovascular diseases from a real-life, prospective cohort (Kailuan study) were included. The monocyte count, HDL-C level and monocyte-to-HDL-C ratio (MHR), calculated as time-averaged cumulative and baseline values, were used as the exposures. Time-to-event …

Live High-Train Low Induced Changes In Hemoglobin Mass And The Erythropoietin-Erythroferrone-Hepcidin Axis In Female Endurance Athletes, Titta Kuorelahti, Johanna K. Ihalainen, Vesa Linnamo, Claire Badenhorst, Oona Kettunen, Ritva Mikkonen

Research outputs 2022 to 2026

The effects of a 21-day live high-train low (LHTL) on hemoglobin mass (Hbmass) and iron demand including the erythropoietin (EPO)-erythroferrone (ERFE)-hepcidin axis and routine iron markers were investigated. Fifteen female endurance athletes completed either 21-day LHTL in normobaric hypoxia (2500 m, ~18 h·day⁻¹) (INT, n = 8) or lived and trained in normoxia (CON, n = 7). Hbmass and resting blood were collected before and after the intervention. An additional blood sample was collected on Day 6 for INT. 21-day LHTL increased Hbmass 3.8% in INT (p < 0.001). EPO increased 35.6% from Day 0 to Day 6 in INT (p = 0.037) and then decreased 42.4% from Day 6 to Day 21 (p = 0.019). In INT, no changes were detected in ERFE or hepcidin, and from the routine iron markers only serum transferrin receptor increased from Day 0 to Day 21 (13.9%, p = 0.013). In CON, no changes were detected in Hbmass or iron markers. In INT, Hbmass and ferritin were positively associated (Day 0 to Day 6, p = 0.005). Thus, hepcidin and ERFE may not provide additional information regarding iron demand following 6- or 21-day LHTL compared to routine iron markers. The relationship between Hbmass and ferritin indicates that adequate ferritin levels are needed during hypoxia to support hematological adaptations.

Muscle Imaging Assessments In Sarcopenia: A Statement From China National Center For Orthopedics (Nco) And The East Meets West Action Group Of The European Calcified Tissue Society (Ects), Ling Wang, Shuai Lu, Jiahua Feng, Kairui Ma, Fangfang Duan, Renxian Wang, Xiaoguang Cheng, Yajun Liu, Yuuki Imai, Hailing Chen, Claus C. Glüer, Giuseppe Guglielmi, Annegreet G. Vlug, Jianmin Liu, Klaus Engelke, Mei Li, Marc Sim, Salvatore Minisola, Xieyuan Jiang

Research outputs 2022 to 2026

Sarcopenia, characterized by progressive loss of muscle mass, strength, and function, significantly impacts patient outcomes. Accurate assessment of muscle mass is essential for its diagnosis. Currently the agreement on how to use imaging for sarcopenia detection is still debated and how well the muscle imaging assessments correlate with muscle function needs further agreement. Recognizing the critical role of imaging in this process, the China National Center for Orthopedics (NCO) and the East Meets West Action Group of European Calcified Tissue Society (ECTS) convened a working group endorsed by the Board of the ECTS. This paper aims to evaluate the utility …

Non-Pharmacological Supportive Care Interventions During Immunotherapy For People With Cancer: A Systematic Scoping Review And Future Directions, Morgan J. Farley, Brighid R. Scanlon, Megan Crichton, Ashley M. Bigaran, Amy C.M. Barnes, Nicolas H. Hart, Patsy M. Yates, Melissa L. Eastgate, Kim Alexander

Research outputs 2022 to 2026

Purpose: Immunotherapy has transformed cancer treatment and outcomes. Patients receiving immunotherapy often encounter immune-related and treatment-related adverse events, leading to substantial supportive care needs. Currently, no recommendations exist to guide the use of non-pharmacological supportive care interventions for people with cancer undergoing immunotherapy treatments. This review aims to summarise the available evidence regarding non-pharmacological supportive care strategies to inform future clinical management and research directions.

Methods: Six electronic databases (PubMed, CINAHL, EMBASE, PsycInfo, Web of Science and Scopus) were systematically searched for studies on non-pharmacological supportive care interventions for adults undergoing immunotherapy, published from October 2014 to October 2024.

Results: …

Organizational Sustainability In The Face Of Digital Transformation With A Bibliometric And Content Analysis For Future Research Agenda, Rahmanwali Sahar, Md Abu Jahid, Hasan Fauzi, Md Harun Ur Rashid

Research outputs 2022 to 2026

This study explores the intersection of organizational sustainability and digital transformation by providing a comprehensive bibliometric and content analysis of existing literature. Using data from the Scopus database, the research employs bibliometric tools such as VOSviewer to analyze trends, identify key themes, and map the intellectual structure of the field. The analysis focuses on publications from 2016 to 2025, highlighting the significant growth of research in this domain, particularly after 2018, indicating a rising scholarly interest in sustainable digital innovation. The Results reveal that most publications are concentrated in high-impact journals, with top contributing countries including the United States, the …

Safety Of Bioelectrical Impedance Analysis In Patients With Cardiac Implantable Electronic Devices: A Systematic Review, Leonardo J. Uribe-Cavero, Fabian A. Chavez-Ecos, Kiara Camacho-Caballero, José Carlos Grados-Pintos, Patricia Vera-Maccha, Anthony Siguas-Huasasquiche, Dinesh Sharma, Carlos J. Toro-Huamanchumo

Research outputs 2022 to 2026

Background Bioelectrical impedance analysis (BIA) is widely used to assess body composition. However, its safety in patients with cardiac implantable electronic devices (CIEDs) remains uncertain owing to potential electromagnetic interference (EMI). Objective This study aimed to evaluate potential complications associated with clinical-grade BIA use in patients with CIEDs, based on currently available evidence. Methods We conducted a systematic review of studies published up to December 26, 2024, identified through PubMed, Embase, Scopus, and the Cochrane Library. The primary outcome was the occurrence of adverse events, including EMI, device malfunction, or arrhythmias. Results Of 3668 records, 6 cohort studies (n = …

Sertraline To Reduce Recidivism In Impulsive Violent Offenders (Reinvest): A Randomised Double Blind Clinical Trial, Tony Butler, Emaediong I. Akpanekpo, Lee Knight, Kristy Robledo, David Greenberg, Andrew Ellis, Stephen Allnutt, Kay Wilhelm, Alison Jones, Rodney Scott, Bianca Ton, Luke Grant, Philip Mitchell, Ross Tynan, Jocelyn Jones, Dominic Villa, Duncan Chappell, Carolynn Dixon, Alison Churchill, Val Gebski, Tony Keech, Peter W. Schofield

Research outputs 2022 to 2026

Background: Biological studies suggest serotonin modulation via selective serotonin reuptake inhibitors (SSRIs) might reduce impulsive violence, however, robust evidence in offender populations is limited. We aimed to determine whether sertraline reduces violent reoffending compared with placebo in highly impulsive men with recurrent violent offending.

Methods: We conducted a double-blind, placebo-controlled, randomised clinical trial in community settings in New South Wales, Australia. Eligible participants were men aged 18 years or older with ≥2 prior violent convictions and a Barratt Impulsiveness Scale score ≥70. Following a 4-week single-blind active run-in phase with sertraline, participants were randomly assigned (1:1, minimization stratified by key …

The Effects Of Acute And Chronic Exercise On Lipocalin-2 In Middle-Aged And Older Adults: A Randomized Control Trial, Carlie Bauer, Marc Sim, Cassandra Smith, Rhiannon Healy, Andrew Garnham, Navabeh Zare-Kookandeh, Elizabeth Byrnes, Mary N. Woessner, Joshua R. Lewis, Itamar Levinger

Research outputs 2022 to 2026

Objective Chronically elevated circulating lipocalin-2 (LCN2) levels are implicated in poor energy regulation, increased cardio-metabolic disease risk, and poor physical function. Exercise is known to improve these factors, but whether LCN2 is modifiable by exercise is not clear. We examined the effect of acute and chronic exercise on LCN2 levels and whether this relates to glucose regulation, body composition, and physical function. Design and methods Thirty-three middle-aged and older adults (45–84 years, median body mass index 26.21 kg/m²) completed an acute high-intensity interval exercise session (HIIE). Participants were randomized to 4 weeks of high-intensity interval training (HIIT) or …