Digital Commons Network^™

Yoga Storytelling As An Active Learning Approach: Insights From Early Childhood Classroom Practice, Serap Sevimli-Celik

Research outputs 2022 to 2026

Movement plays a central role in early childhood learning, supporting children’s physical development, emotional regulation and cognitive engagement. In recent years, educators have been paying more attention to movement-based approaches to enhance classroom learning experiences. Yoga, when adapted for young children, offers opportunities for playful movement, body awareness and relaxation. This paper reflects on my experiences as a movement educator and explores how yoga can support active learning in early childhood classrooms. Drawing on a series of 30-minute yoga storytelling sessions delivered to five- and six-year-old children in a preschool setting, the paper illustrates how yoga storytelling can be integrated …

Leveraging Collective Resources For Digital Transformation: The Role Of Tourism Trade Associations Under The Resource-Based View, Tianyu Zheng, Ke Zhang, Songshan (Sam) Huang, Bing Hu

Research outputs 2022 to 2026

In the digital age, while hospitality and tourism (H&T) firms accelerate digital transformation to stay competitive, the role of tourism trade associations as external resource providers in these firms’ digital transformation process remains underexplored. Drawing on resource-based theory (RBT), this study examines how tourism trade associations influence H&T firms’ digital transformation and explores the moderating effects of marketization and business climate. Using 2,049 firm-year observations of 144 publicly listed H&T firms (2009–2022), this study finds evidence suggesting that tourism trade associations facilitate digital transformation. Crucially, we find that marketization and business climate negatively moderate this relationship, indicating a substitution effect …

Aphasia Treatment Research: A Decision-Making Tool To Guide The Design Of Phased Trials From The Collaboration Of Aphasia Trialists (Cats) Trials For Aphasia Panel, Erin Godecke, Emily Brogan, Rebecca Palmer, Marian C. Brady, Frank Becker, Caterina Breitenstein, Sonia Brownsett, Julius Fridriksson, Katerina Hilari, Argye E. Hillis, Paola Marangolo, Miranda L. Rose, Shirley Thomas, Donna C. Tippett, Julie Bernhardt, Kathryn S. Hayward

Research outputs 2022 to 2026

Background: Systematic reviews of randomised controlled trials with meta-analyses indicate that speech and language therapy for aphasia after stroke is effective in improving communication. However, high-quality evidence to identify an intervention’s target population (who), regimen (what), timing (when), and dose (how much) is lacking. The predominance of underpowered aphasia trials and comparative studies with design limitations may be attributed to: 1) the perceived complexity of designing trials of interventions for a complex behaviour such as human communication, 2) the lack of funded research in the field and 3) a lack of training and understanding in the field of aphasiology regarding …

Beyond Compliance: Transformative Co-Design For Gender-Based Violence Prevention In Higher Education, Narelle Lemon, Christina Gray, Jason Goopy, Lisa Holmes, Bec Ball, Melissa Perry, Elisa Fear

Research outputs 2022 to 2026

This study examines how university staff and students experience transformative learning through voluntary participation in a gender-based violence (GBV) prevention programme that transcended compliance-oriented approaches. While universities increasingly rely on mandatory modules that fail to create sustainable change, this research investigates whether self-nominated participation and co-design pedagogy can foster genuine transformation and voice development among participants from diverse disciplinary backgrounds. A qualitative multi-method design examined eight university students (aged 18–24) at an Australian university through pre-post focus groups, observational field notes, and artefact analysis. Participants voluntarily engaged in workshops co-designing peer-focused social media prevention messaging. Inductive thematic analysis identified patterns …

Bishop’S Categories 40 Years On: Reclaiming And Sustaining Story And Culture Authors, Helen Adam, Libby Jackson-Barrett, Nicola Daly, Maria Nayr De Pinho Correia Ibrahim, Gloria Boutte

Research outputs 2022 to 2026

Bishop’s foundational framework for analysing multicultural children’s literature has provided essential tools for understanding cultural representation for almost 40 years. However, the evolution of First Nations children’s literature and the increased Indigenous control over publishing and storytelling suggest Bishop’s original three categories may not fully capture the complexity of contemporary Indigenous storytelling. This study reports on a comprehensive analysis of 750 books by and about Aboriginal and Torres Strait Islander peoples, employing yarning methodology and Indigenous research approaches to examine patterns of cultural representation across historical periods. Whilst Bishop’s categories remain relevant, two additional categories emerged: Culturally Sustaining and Cultural …

Commission Pathways For Sexual Offences Against Children: A Novel Methodological Approach Exposing Distinct Pathways As A Function Of Offending History, Kelly Jackson, Raphaële Arlettaz, Alfred Allan, Joseph Clare, Frank Morgan, Hilde Tubex

Research outputs 2022 to 2026

Purpose: Using neural network analysis, we examined how specific dispositional and situational factors influence pathways for the commission of sexual offending against children. Use of non-linear multifactorial models is still developing in psychological and criminological research, making this a unique contribution to these fields.

Method: We used prior offence status as the outcome variable in a multi-stage analytical strategy that included chi-squared analysis, sequential binary regression and neural network modelling. Subjects came from a database containing pre-collected psychological and criminological information on Western Australian men who had sexually offended. An initial sample of offenders convicted of sexual offences against children …

Crisis, Credit Risk, And Productivity: Lessons From The Vietnamese Banking Sector During Covid-19, Van Nguyen, Phuong Thanh Le, Reza Kiani Mavi, Amir Arjomandi

Research outputs 2022 to 2026

This study investigates how an unprecedented systemic shock, the COVID-19 pandemic, reshaped bank productivity and intermediation efficiency in Vietnam, one of the fastest-growing emerging economies. We develop a novel risk-adjusted total factor productivity (TFP) measure based on the by-production Luenberger–Hicks–Moorsteen (LHM) indicator, which incorporates non-performing loans as undesirable outputs to better capture credit-risk dynamics. Using a balanced panel covering both the pre-pandemic and pandemic periods (2016–2022), our results show that Vietnamese banks experienced a general decline in productivity before and during COVID-19, driven largely by reductions in technical and scale efficiency. However, foreign and state-owned banks recorded stronger technological progress …

Decoupling Sustainability And Performance: How Government Infrastructure Projects In Australia Fare On Strategic Environmental Commitments, Richard Hughes, Kerry Brown

Research outputs 2022 to 2026

Australian government organisations are pivotal in helping to meet the United Nations sustainable development goals. Yet while these organisations promote sustainability in their strategic plans, they struggle to embed these same commitments into their own infrastructure and construction projects. This study examines this persistent disconnect using the lens of strategic decoupling, which explains how organisations symbolically align with external expectations while internal practices remain unchanged. Using a two-stage qualitative design, we conducted a positivist discourse analysis of strategic artefacts from six government organisations and a theoretically informed interpretivist analysis of 30 interviews with project professionals, framed by strong structuration theory. …

Early-Life Pathways To Inequalities In Child Mental Health: Evidence From Eight Birth Cohorts, Demetris Avraam, Gabriella Melis, Tim Cadman, Jennie Carson, Marie Aline Charles, Yu Wei Chua, Ahmed Elhakeem, Joaquín Escribano, Veit Grote, Dariusz Gruszfeld, Kathrin Guerlich, Rae-Chi Huang, Jennifer R. Harris, Jesus Ibarluzea, Jordi Julvez, Berthold Koletzko, Ashleigh Lin, Unai Martin, Rosemary Mceachan, Maria Melchior, Phillip Melton, Johanna Thorbjornsrud Nader, Angela Pinot De Moira, Maja Popovic, Simona Porru, Lorenzo Richiardi, Blanca Sarzo, Daniela Schlüter, Jordi Sunyer, Morris Swertz, Elvira Verduci, John Wright, Annick Xhonneux, Tiffany Yang, Daniela Zugna, Anne-Marie Nybo Andersen, Katrine Strandberg-Larsen, David Taylor-Robinson

Research outputs 2022 to 2026

Background: Socioeconomic inequalities in children's emotional and behavioural problems are already present at school entry. We examined associations between early-life socioeconomic conditions and children's externalising and internalising problems and assessed whether early-life risk factors mediated these associations.

Methods: We analysed harmonised individual participant data from eight birth cohorts within the EU Child Cohort Network. Maternal educational level during pregnancy was used as an indicator of early-life socioeconomic conditions (SECs). Scores of children's externalising and internalising problems around school entry age were used as the outcome variables. Inequalities were quantified using the Slope Index of Inequality which captures the difference in …

Employer Perspectives On Graduates’ Professional Identity Formation In The Workplace, Denise Jackson, Michael Tomlinson

Research outputs 2022 to 2026

Professional identity (PI) is recognised as a crucial dimension in how graduates negotiate the transition to employment and move towards a pathway of sustainable professional development. Perspectives on PI have been derived mainly from higher education students with little attention given to the perspective of employers involved in supporting and supervising graduates in the workplace. Accordingly, the study surveys 339 industry professionals to examine their perceptions of how formed graduates’ PI is at different times after recruitment and the influence of personal, organisational and external factors on identity formation at work. Employers recognised how a well-formed PI enables graduates to …

Factors That Impede Women's Contraceptive Care Needs During And Immediately After Incarceration In New South Wales, Australian. Qualitative Perspectives Of Professional Staff Working With Incarcerated Women, Helene Smith, Mandy Wilson, Basil Donovan, Jocelyn Jones, Tony Butler, Paul Simpson

Research outputs 2022 to 2026

Introduction: Women with a history of incarceration report higher rates of pregnancy and abortion, lower contraception use and poorer birth outcomes compared to other women in the community. This suggests family-planning and reproductive-health needs that are not well served by current models of care. Despite this, little is known about how contraception is provided within Australian carceral settings, or the structural barriers experienced by professional staff working in these environments. We report findings from a qualitative study conducted in New South Wales (NSW), Australia, describing professional staff's views of factors that support or impede women's contraceptive care needs both during …

Fostering Authentic Corporate Social Responsibility Through Place-Based And Relational Methodologies In Mining Governance: A Global Synthesis, Mehran Nejati, Eduardo Ordonez-Ponce, Rumen Rachev, Belen Lopez Vazquez

Research outputs 2022 to 2026

Purpose: As the global economy shifts towards low-carbon development, sustainable mining practices are becoming increasingly vital for balancing resource extraction with environmental and social responsibilities. This study aims to critically evaluate how traditional corporate social responsibility (CSR) frameworks fall short in addressing power asymmetries and territorial impacts, and to explore how place-based and relational methodologies can foster authentic corporate social responsibility (ACSR) in mining governance.

Design/methodology/approach: This review synthesises findings from 77 peer-reviewed studies published between 2015 and 2025, covering diverse global mining contexts. The analysis identifies transformative themes through a qualitative meta-synthesis approach, focusing on governance practices that empower …

Hamstring Strength Assessment Methods In Sport: A Systematic Review And Meta-Analysis Of Post-Activity Strength Decrements, Asymmetry Benchmarks, And Measurement Reliability, Adam E. Sundh, Nicholas J. Ripley, A. J. Lamb, Paul Comfort

Research outputs 2022 to 2026

Hamstring strain injuries (HSI) represent one of the most prevalent and recurrent injuries in sport, making reliable strength assessment essential for neuromuscular monitoring in athletic populations. Despite the breadth of available testing modalities, no comprehensive synthesis of assessment methods, their reliability, post-activity strength responses, or normative asymmetry values has been undertaken. This systematic review and meta-analysis aims to evaluate the reliability of hamstring strength assessment methods, quantify the time-course of strength decrements following competition, establish normative inter-limb asymmetry benchmarks, and identify gaps to guide future assessment practices. PubMed, Scopus, SPORTDiscus, and Web of Science were searched from inception to November …

It's The Most Diverse Job I’Ve Ever Had: What Do Registered Nurses Working In Australian Schools Do?, Anita Moyes

Research outputs 2022 to 2026

Although nurses have been working in Australian schools for many decades, research has focused primarily on narrow aspects of clinical practice or service delivery in specific regions. The aim of this study was to identify the domains of practice registered nurses report in a typical working day in Australian schools, using interview data from a national sample. Forty-five nurses working in government and nongovernment schools in every state and territory of Australia participated. Interviews were analyzed using inductive content analysis ( Elo & Kyngas, 2008). Six distinct domains of practice characterized nursing work in Australian schools: (i) responding to diverse …

Living On Display: Reciprocal Gazes, Everyday Encounters, And The Politics Of Visibility In The Sunshine Coast Tourism Community, Madura Thiwanka Pathirana, Noel Scott

Research outputs 2022 to 2026

This community case study analyses the production, negotiation, and contestation of reciprocal gazes within everyday settings, particularly focusing on contemporary lifestyle tourism destinations, and the examination of the Sunshine Coast, Australia. Based on 48 in-depth interviews with tourists and locals, this case study looks at the politics of visibility that are part of host-guest relations in everyday encounters at the beach, cafe, marketplace, and online-mediated market. Intersecting with critical tourism studies, and tourism studies on the traveler, host, and reciprocal gaze, this study focuses on residents' experiences of being observed, judged, and photographed and the impacts of their experiences on …

Making Room For ‘Feelings’: What's At Stake For The Theory Of Practice Architectures?, George Variyan, Brad Gobby

Research outputs 2022 to 2026

This paper responds to Thelin, K. [2024. What about feelings? Elaboration on and consideration of the theoretical construct of emotions in practice and practice architectures. International Journal of Leadership in Education, 1–14] intriguing proposal that the theory of practice architectures (hereafter TPA) would benefit from an augmentation to its oft-repeated analytical mantra of ‘sayings, doings and relatings’ by adding the notion of feelings. Thelin's work is motivated by the increasing realisation amongst adherents that TPA has thus far been relatively silent on how emotions mediate practice. As such, there are ongoing efforts to think through the place of emotions in …

Optimal Two-Point Loading Strategy For Accurate Leg Press Force–Velocity Assessment, Takuya Nishioka, Shota Yamaguchi, Ayumi Yoshikawa, Naoki Ikeda, Daiki Hajima, Naoko Yabuno, Yasuhiro Kunita, Yuta Hashimoto, Anna Aoki, Miina Takahashi, Kazunori Nosaka, Takayuki Inami

Research outputs 2022 to 2026

Accurate assessment of an individual force–velocity (F–V) profile is essential for prescribing targeted resistance training; however, F–V outcomes depend strongly on the testing method used. This study examined the concurrent validity of the F–V relationship in a horizontal leg press exercise by comparing two-point methods, which use pairs of different loads relative to body weight, with a multiple-point method using a wider range of loads. Sixteen men (mean ± SD, age: 20.0 ± 1.4 years, height: 172.4 ± 6.3 cm, body mass: 69.2 ± 7.6 kg) performed maximal-effort horizontal dynamic leg press actions on a device equipped with pneumatic artificial …

Rrto: A High-Performance Transparent Offloading System For Model Inference In Mobile Edge Computing, Zekai Sun, Xiuxian Guan, Zheng Lin, Yuhao Qing, Haoze Song, Zihan Fang, Zhe Chen, Fangming Liu, Heming Cui, Wei Ni, Jun Luo

Research outputs 2022 to 2026

Deploying Machine Learning (ML) applications on resource-constrained mobile devices remains challenging due to limited computational resources and poor platform compatibility. While Mobile Edge Computing (MEC) offers an offloading-based inference paradigm using GPU servers, existing approaches can be divided into non-transparent and transparent methods, with the former necessitating source-code modifications. Non-transparent offloading achieves high performance but requires intrusive code changes, limiting compatibility with diverse applications. Transparent offloading, in contrast, offers wide compatibility but introduces two challenges: performance degradation under MEC's low and fluctuating bandwidth, where per-operator remote procedure calls (RPCs) inflate end-to-end latency and energy consumption; and black-box logic reconstruction, which …

Selective Human Resource Practices, Psychological Safety Climate And Employee Wellbeing, Yvonne Brunetto, Matthew J. Xerri, Geremy Farr-Wharton

Research outputs 2022 to 2026

Purpose: Engineers and healthcare professionals perceive higher levels of stress compared with the general population, suggesting that past human resource management (HRM) systems have failed to manage them appropriately. This study examines whether psychosocial safety climate (PSC) acts as a psychological conduit in translating HRM practices and mediating their impact on wellbeing using the common good HRM (CGHRM) and Conservation of Resources theoretical frameworks.

Design/methodology/approach: Data were collected using surveys collected at two points – one-month apart, and then analysed using structural equation modelling (Analysis of Moment Structures) to manipulate survey data from 300 matched employees.

Findings – The variance …

The Contribution Of Nursing And Midwifery To Achieving The Sustainable Development Goals: A Bibliometric Analysis, David C. Benton, Andrew D. Benton, Kate Buchanan, Gemma Doleman, Karen Strickland, Lisa Whitehead

Research outputs 2022 to 2026

Background: Nurses and midwives are central to achieving the Sustainable Development Goals (SDGs) as the largest regulated sector of the global health workforce and as professions explicitly encouraged by the International Council of Nurses and the World Health Organization to advance the 2030 Agenda. This paper updates a 2016 bibliometric analysis to examine changes in nursing and midwifery scholarly engagement with the SDGs.

Methods: A bibliometric analysis of Scopus, CINAHL Ultimate, and PubMed was undertaken for publications from 2000 to 2025 containing Millennium Development Goal (MDG) or Sustainable Development Goal (SDG) terminology in nursing and midwifery literature. VOSviewer was used …

The Ecology Of Hope: Building Rainbows In Education Systems, Jennifer Achari

Research outputs 2022 to 2026

Hope is frequently invoked in education, yet rarely theorised. Where it has been theorised, it has been understood in two largely separate ways: as an individual psychological capacity, in the positive-psychology tradition and as a critical-emancipatory stance, in the pedagogy of hope. This article proposes a third: a theory, the ecology of hope, that locates hope not in the individual alone but in the relationship between a person and the systems that surround them. Bringing the cognitive psychology of hope into dialogue with ecological systems theory, the social-ecological account of resilience, and utopian methodology, in which a better society is …

The Influence Of Self-Compassion On The Mental Health And Well-Being Of Women Experiencing Infertility: A Systematic Review, Shwikar Othman, Mitra Javanmard, Lauren Roberts, Lisa Conlon, Mary Steen

Research outputs 2022 to 2026

Infertility can cause significant distress to women, increasing the risk of anxiety and depression. This systematic review examined the influence of self-compassion interventions on mental health and well-being among women experiencing infertility. The review was conducted in accordance with Joanna Briggs Institute (JBI) methodology and reported following PRISMA guideline. Databases searched included Medline, Embase, Ovid nursing database, Emcare, PsycINFO and Cochrane Library from inception to November 2024. Quality assessment was conducted using JBI critical appraisal tools. Title and abstract screening was conducted by three reviewers, and data extraction was performed independently by two reviewers. Sixteen studies met the inclusion criteria, …

When Does The Peak Countermovement Jump Performance Occur? Mapping Peak-Trial Timing Across Six Clustered Repetitions, Karol Kruczek, Szymon Karpęcki, Tim Gabbett, Jason Lake, Michał Nowak

Research outputs 2022 to 2026

Force-plate countermovement jump (CMJ) testing is widely used to assess neuromuscular status, yet monitoring interpretation often relies on best-trial values from abbreviated protocols, potentially biasing conclusions when the session maximum occurs beyond the sampled attempts. We mapped peak-trial timing across a six-trial clustered (3 + 3) CMJ protocol for seven outcome and strategy force–time metrics, and tested whether this peak-trial pattern was preserved between personal best (PB) and typical state (TS) monitoring sessions, both defined using modified reactive strength index (mRSI) as the primary selection variable. Retrospective dual-force-plate data (1000 Hz; August 2020–December 2025) were analysed from 314 athletes who …

Implementation Strategies For Evidence-Based Healthcare Interventions In Rural And Remote Settings: A Scoping Review, Anna Chapman, Cadeyrn J. Gaskin, Hannah Beks, Charlene Wright, Skye Marshall, Elizabeth A. Johnston, Rebecca J. Bergin, Sharina Riva, Fiona Crawford-Williams, Camille E. Short, Nicole Kiss, Sze Lin Yoong, Nicolas H. Hart, Anna Wong Shee, Helena Rodi, Hannah Jongebloed, Anna Ugalde

Research outputs 2022 to 2026

Globally, people living in rural and remote areas experience poorer healthcare access and outcomes than urban populations. Applying implementation strategies that support the translation of evidence-based healthcare interventions may help reduce these inequities; however, real-world implementation is complex, and it remains unclear how strategies are applied and tailored to rural and remote contexts. This scoping review synthesised evidence on implementation strategies for healthcare interventions in rural and remote settings of high-income countries. Five databases (Ovid MEDLINE, Embase, Cochrane CENTRAL, CINAHL, Web of Science) were searched for peer-reviewed studies published between 1/1/2000 and 25/10/2024. Extracted data were synthesised using a descriptive …

How I Cook With No Kitchen: An Investigation Of How #Microapartment Kitchens Are Depicted On Tiktok, Joelie Mandzufas, Karen Lombardi, Dorian Winter, Sarah Foster, Siobhan Hickling, Gina S.A. Trapp

Research outputs 2022 to 2026

Background: Physical constraints of small apartment kitchens and the influence of the surrounding community food environment may impact food practices of apartment residents. Social media portrayal of these features may influence public perception of apartment living. Aim: This project aimed to describe the public depiction of small apartment kitchen and cooking facilities. Methods: Content analysis of TikTok videos posted with small apartment-related hashtags was determined the portrayal of kitchen facilities, residents’ food practices, and hypothesised barriers to healthy cooking and eating practices. Current residents of small apartments compared these video depictions to their own experience. Results: We found TikTok videos …

Insulin Resistance As A Mediator Of Physical Activity's Effects On Beta-Amyloid Accumulation And Tau Phosphorylation: A Scoping Review, Michael G. Slee, Joanne Scotney, Stephanie R. Rainey-Smith, Kirk I. Erickson, Hamid R. Sohrabi, Giuseppe Verdile, Belinda M. Brown

Research outputs 2022 to 2026

Background Type 2 diabetes is associated with increased Alzheimer’s disease risk and brain beta amyloid (Aβ) burden, suggesting an underlying mechanistic relationship between Alzheimer’s disease and type 2 diabetes. Animal studies show exercise reduces levels of brain Aβ and tau, and while human studies are somewhat limited, some studies have reported physical activity is associated with lower brain Aβ and tau levels. Exercise has well established links to reductions in insulin resistance; thus, as physical activity can impact both insulin resistance and Alzheimer’s disease pathology and/or biomarkers, it is reasonable to hypothesise that a mediating relationship may exist. The objective …

Leveraging Consumer Socialisation Agents To Increase Indigenous Student Participation In Higher Education, Melissa Fong-Emmerson, Braden Hill, Claire Lambert, Maria M. Ryan, Rebekah Dougan

Research outputs 2022 to 2026

Purpose – Socialisation agents, including family, peers, Elders, teachers, mass media and community networks, significantly influence students’ decisions to pursue higher education (HE). This paper aims to further explore how these agents, within the framework of consumer socialisation theory, act as influential forces at the early stages of the decision-making process, shaping perceptions and providing motivation for Indigenous students’ educational choices. Design/methodology/approach – A three-phase narrative inquiry method was used, including autobiographical accounts from students, yarning sessions with peers and one-on-one interviews. This participatory approach centred Indigenous knowledges to inform culturally responsive social marketing strategies. Findings – The study identified …

Nursing Leadership And Pandemic Preparedness Via Game-Based Learning Simulation: A Narrative Review (Registered Nurses And Undergraduate Nursing Students), Scott James Andrews, Olivia Gallagher, Alecka Miles, Carol Crevacore, Brennen Mills

Research outputs 2022 to 2026

Background: Early progression of newly registered nurses into leadership roles is commonplace in clinical settings. Nurses and student nurses can prepare for leadership by gaining exposure through simulation-based learning. A novel and expanding modality are game-based learning (GBL) simulation. Nurse leaders play a crucial role during pandemics, guiding their teams through crises and ensuring effective response strategies. Reviewing the literature to identify the content, structure, and effectiveness of current pandemic preparedness and GBL simulation in nursing education is necessary to identify lessons learnt during the COVID-19 pandemic response to guide workforce preparation for future surge planning. Aim: The aim of …

Plasma Aβ42/40 Predicts Progression From Aβ-Amyloid Negative To Positive Pet Scans, Azadeh Feizpour, Vincent Doré, Pierrick Bourgeat, James D. Doecke, Rodrigo Canovas, Simon M. Laws, Tenielle Porter, Kun Huang, Christopher Fowler, Ralph N. Martins, Paul Maruff, Hamid R. Sohrabi, Michael W. Weiner, John C. Morris, Tammie L.S. Benzinger, Suzanne E. Schindler, Randall J. Bateman, Yan Li, Ovod Vitaliy, Larry Ward, Jurgen Mejan-Fripp, Colin L. Masters, Victor L. Villemagne, Christopher C. Rowe

Research outputs 2022 to 2026

Background The agreement between plasma Aβ42/40 and Aβ positron emission tomography (PET) is approximately 75 %, with ∼85 % of discrepancies due to positive plasma but negative PET results. It is unclear whether this reflects Aβ changes in plasma before PET-detectable. Objectives To assess the influence of Aβ42/40 positivity on risk of progression to Aβ PET positivity, and feasibility of using plasma Aβ42/40 tests to enrich a primary prevention trial. Design A prospective longitudinal cohort study. Setting Participants of Australian Imaging, Biomarkers and Lifestyle study (AIBL), Alzheimer’s Disease Neuroimaging Initiative (ADNI), and Open Access Series of Imaging Studies 3 (OASIS3). …

The Gut Microbiome Mediates The Association Between A Flavonoid-Rich Diet And Masld In A Population-Level Analysis, William Bell, Amy Jennings, Nicola P. Bondonno, Andre Franke, Corinna Bang, Marcus Both, Jan Kassubek, Hans Peter Müller, Jan Borggrefe, Wolfgang Lieb, Tilman Kühn, Aedín Cassidy

Research outputs 2022 to 2026

Purpose: A growing body of evidence suggests diets rich in flavonoids may protect against metabolic-dysfunction associated steatotic liver disease (MASLD) development and progression. As the gut microbiome is important in the biotransformation of flavonoids to their constituent bioactive metabolites, studies on the potential mediating role of the gut microbiome in the association between dietary flavonoid intakes and MASLD are warranted but lacking. Thus, this study aims to examine the associations between a diet rich in flavonoids and MASLD, and assess the potential mediating role of the gut microbiome. Methods: In a cross-sectional analysis (n = 531), using the FlavoDiet score …