Digital Commons Network^™

Leukocyte Surface Biomarkers Implicate Deficits Of Innate Immunity In Sporadic Alzheimer's Disease, Xin Huang, Yihan Li, Christopher Fowler, James D. Doecke, Yen Ying Lim, Candace Drysdale, Vicky Zhang, Keunha Park, Brett Trounson, Kelly Pertile, Rebecca Rumble, John W. Pickering, Robert A. Rissman, Floyd Sarsoza, Sara Abdel-Latif, Yong Lin, Vincent Doré, Victor Villemagne, Christopher C. Rowe, Jurgen Fripp, Ralph Martins, James S. Wiley, Paul Maruff, Jacobo E. Mintzer, Colin L. Masters, Ben J. Gu

Research outputs 2022 to 2026

Introduction:

Blood-based diagnostics and prognostics in sporadic Alzheimer's disease (AD) are important for identifying at-risk individuals for therapeutic interventions.

Methods:

In three stages, a total of 34 leukocyte antigens were examined by flow cytometry immunophenotyping. Data were analyzed by logistic regression and receiver operating characteristic (ROC) analyses.

Results:

We identified leukocyte markers differentially expressed in the patients with AD. Pathway analysis revealed a complex network involving upregulation of complement inhibition and downregulation of cargo receptor activity and Aβ clearance. A proposed panel including four leukocyte markers – CD11c, CD59, CD91, and CD163 – predicts patients’ PET Aβ status with an …

Patterns And Implications Of Neurological Examination Findings In Autosomal Dominant Alzheimer Disease, Jonathan Vöglein, Nicolai Franzmeier, John C. Morris, Marianne Dieterich, Eric Mcdade, Mikael Simons, Oliver Preische, Anna Hofmann, Jason Hassenstab, Tammie L. Benzinger, Anne Fagan, James M. Noble, Sarah B. Berman, Neill R. Graff-Radford, Bernardino Ghetti, Martin R. Farlow, Jasmeer P. Chhatwal, Stephen Salloway, Chengjie Xiong, Celeste M. Karch, Nigel Cairns, Richard J. Perrin, Gregory Day, Ralph Martins, Raquel Sanchez-Valle, Hiroshi Mori, Hiroyuki Shimada, Takeshi Ikeuchi, Kazushi Suzuki, Peter R. Schofield, Colin L. Masters, Alison Goate, Virginia Buckles, Nick C. Fox, Patricio Chrem, Ricardo Allegri, John M. Ringman, Igor Yakushev, Christoph Laske, Mathias Jucker, Günter Höglinger, Randall L. Bateman, Adrian Danek, Johannes Levin, Dominantly Inherited Alzheimer Network

Research outputs 2022 to 2026

Introduction:

As knowledge about neurological examination findings in autosomal dominant Alzheimer disease (ADAD) is incomplete, we aimed to determine the frequency and significance of neurological examination findings in ADAD.

Methods:

Frequencies of neurological examination findings were compared between symptomatic mutation carriers and non mutation carriers from the Dominantly Inherited Alzheimer Network (DIAN) to define AD neurological examination findings. AD neurological examination findings were analyzed regarding frequency, association with and predictive value regarding cognitive decline, and association with brain atrophy in symptomatic mutation carriers.

Results:

AD neurological examination findings included abnormal deep tendon reflexes, gait disturbance, pathological cranial nerve examination findings, …

Plasma Aβ42/40 Ratio, P-Tau181, Gfap, And Nfl Across The Alzheimer's Disease Continuum: A Cross-Sectional And Longitudinal Study In The Aibl Cohort, Pratishtha Chatterjee, Steve Pedrini, James D. Doecke, Rohith Thota, Victor L. Villemagne, Vincent Doré, Abhay K. Singh, Penghao Wang, Stephanie Rainey-Smith, Christopher Fowler, Kevin Taddei, Hamid R. Sohrabi, Mark P. Molloy, David Ames, Paul Maruff, Christopher C. Rowe, Colin L. Masters, Ralph N. Martins, Aibl Research Group

Research outputs 2022 to 2026

Introduction:

Plasma amyloid beta (Aβ)1-42/Aβ1-40 ratio, phosphorylated-tau181 (p-tau181), glial fibrillary acidic protein (GFAP), and neurofilament light (NfL) are putative blood biomarkers for Alzheimer's disease (AD). However, head-to-head cross-sectional and longitudinal comparisons of the aforementioned biomarkers across the AD continuum are lacking.

Methods:

Plasma Aβ1-42, Aβ1-40, p-tau181, GFAP, and NfL were measured utilizing the Single Molecule Array (Simoa) platform and compared cross-sectionally across the AD continuum, wherein Aβ-PET (positron emission tomography)–negative cognitively unimpaired (CU Aβ−, n = 81) and mild cognitive impairment (MCI Aβ−, n = 26) participants were compared with Aβ-PET–positive participants across the AD continuum (CU Aβ+, n = …

Splitting Tensile Strength Of Recycled Tire Steel Fiber-Reinforced Alkali-Activated Slag Concrete Designed By Taguchi Method, Milad Eskandarinia, Mina Esmailzade, Farhad Aslani

Research outputs 2022 to 2026

Despite offering several benefits in terms of environment and economics, few studies were conducted on the ground granulated blast furnace slag (GGBFS) based alkali-activated concrete reinforced with recycled tire steel fibers (RTSFs). Therefore, this paper employed the Taguchi method to investigate and optimize the influence of GGBFS content, the alkaline solution to GGBFS content ratio, sodium hydroxide solution concentration, and RTSF volume fraction on splitting tensile strength (STS) of recycled tire steel fiber-reinforced alkali-activated slag concrete (RTSFR-AASC). The microstructural evaluation was done through scanning electron microscopy, and Fourier transform infrared spectroscopy (FTIR) analyses. The results indicated that the fiber content, …

Vitamin D Supplementation And Exercise For Improving Physical Function, Body Composition And Metabolic Health In Overweight Or Obese Older Adults With Vitamin D Deficiency: A Pilot Randomized, Double-Blind, Placebo-Controlled Trial, Jakub Mesinovic, Alexander J. Rodriguez, Mavil May Cervo, Anoohya Gandham, Cecilia L. H. Xu, Costas Glavas, Barbora De Courten, Ayse Zengin, Peter R. Ebeling, David Scott

Research outputs 2022 to 2026

Purpose:

Vitamin D supplementation may have non-skeletal health benefits and enhance exercise responsiveness, particularly in those with low vitamin D levels. We determined whether, compared with placebo, vitamin D supplementation taken prior to and during a 12-week exercise program improves physical function, body composition or metabolic health, in overweight and obese older adults with vitamin D deficiency.

Methods:

Fifty overweight or obese older adults (mean ± SD age: 60 ± 6 years; BMI 30.6 ± 5.7 kg/m2) with vitamin D deficiency (25-hydroxyvitamin D [25(OH)D] < 50 nmol/L) were recruited. Participants were randomly allocated to receive either vitamin D3 (4000 IU/day) or matching placebo for 24 weeks. Between weeks 12 and 24, all participants completed multi-modal exercise three days per week while continuing with vitamin D/placebo. Mean changes in physical function (primary outcome: gait speed), body composition and biochemical parameters at weeks 12 and 24 were compared between groups.

Results:

Vitamin D supplementation, with or without exercise, had no effect on gait speed. From baseline …

The Importance Of Trust And Authenticity Among Stakeholders Involved In Higher Education Data Infrastructure Redevelopments: An Australian Critical Discourse Study, Elizabeth Cook

Research outputs 2022 to 2026

Governments require higher education providers (HEPs) to be transparent in their use of public funds and have developed specialised higher education (HE) data infrastructure to enable the data transfer from HEPs to government departments. In 2018, Australia’s Department of Education, Skills and Employment launched Transforming the Collection of Student Information (TCSI) to enhance HE data infrastructure for student data transfer. This critical discourse study explores the discourses, discursive strategies and perspectives surrounding TCSI. Findings included HEP issues and concerns that the interviewees believed were inadequately addressed or ignored despite the Department’s claims of extensive engagement with HEPs to achieve mutually …

Spatial Heterogeneity In Sediment And Carbon Accretion Rates Within A Seagrass Meadow Correlated With The Hydrodynamic Intensity, Jiarui Lei, Rachel Schaefer, Phil Colarusso, Alyssa Novak, Juliet C. Simpson, Pere Masqué, Heidi Nepf

Research outputs 2022 to 2026

The majority of the carbon stored in seagrass sediments originates outside the meadow, such that the carbon storage capacity within a meadow is strongly dependent on hydrodynamic conditions that favor deposition and retention of fine organic matter within the meadow. By extension, if hydrodynamic conditions vary across a meadow, they may give rise to spatial gradients in carbon. This study considered whether the spatial gradients in sediment and carbon accretion rates correlated with the spatial variation in hydrodynamic intensity within a single meadow. Field measurements were conducted in three depth zones across a Zostera marina L. (eelgrass) meadow in Nahant …

Diagnostic Accuracy Of Autoverification And Guidance System For Covid-19 Rt-Pcr Results, Yingmu Cai, Mengyu Liu, Zhiyuan Wu, Cuihong Tian, Song Qiu, Zhen Li, Feng Xu, Wei Li, Yan Zheng, Aijuan Xu, Longxu Xie, Xuerui Tan

Research outputs 2022 to 2026

Background:

To date, most countries worldwide have declared that the pandemic of COVID-19 is over, while the WHO has not officially ended the COVID-19 pandemic, and China still insists on the personalized dynamic COVID-free policy. Large-scale nucleic acid testing in Chinese communities and the manual interpretation for SARS-CoV-2 nucleic acid detection results pose a huge challenge for labour, quality and turnaround time (TAT) requirements. To solve this specific issue while increase the efficiency and accuracy of interpretation, we created an autoverification and guidance system (AGS) that can automatically interpret and report the COVID-19 reverse transcriptase-polymerase chain reaction (RT-PCR) results relaying …

Causal Effect Of Pm1 On Morbidity Of Cause-Specific Respiratory Diseases Based On A Negative Control Exposure, Shiyun Lv, Xiangtong Liu, Zhiwei Li, Feng Lu, Moning Guo, Mengmeng Liu, Jing Wei, Zhiyuan Wu, Siqi Yu, Shihong Li, Xia Li, Wenkang Gao, Lixin Tao, Wei Wang, Jinyuan Xin, Xiuhua Guo

Research outputs 2022 to 2026

Background: Extensive studies have linked PM2.5 and PM10 with respiratory diseases (RD). However, few is known about causal association between PM1 and morbidity of RD. We aimed to assess the causal effects of PM1 on cause-specific RD. Methods: Hospital admission data were obtained for RD during 2014 and 2019 in Beijing, China. Negative control exposure and extreme gradient boosting with SHapley Additive exPlanation was used to explore the causality and contribution between PM1 and RD. Stratified analysis by gender, age, and season was conducted. Results: A total of 1,183,591 admissions for RD were recorded. Per interquartile range (28 μg/m3) uptick …

A Cross-Domain Trust Model Of Smart City Iot Based On Self-Certification, Yao Wang, Yubo Wang, Zhenhu Ning, Sadaqat Ur Rehman, Muhammad Waqas

Research outputs 2022 to 2026

Smart city refers to the information system with Internet of things and cloud computing as the core technology and government management and industrial development as the core content, forming a large-scale, heterogeneous and dynamic distributed Internet of things environment between different Internet of things. There is a wide demand for cooperation between equipment and management institutions in the smart city. Therefore, it is necessary to establish a trust mechanism to promote cooperation, and based on this, prevent data disorder caused by the interaction between honest terminals and malicious terminals. However, most of the existing research on trust mechanism is divorced …

An Empirical Examination Of The Antecedents Of Residents' Support For Of Future Film Tourism Development, Deborah Castro, Sangkyun Kim, Guy Assaker

Research outputs 2022 to 2026

This study aimed to develop and test a conceptual model of the antecedents of residents' attitudinal behavior to support future film tourism in a popular tourism destination. These antecedents include: socio-cultural impacts of existing tourism, place attachment, external perceived realism of media programs, and perceived importance of residents' involvement. A total of 416 survey questionnaires were completed from residents living in the province of Seville, Spain. Partial least squares-structural equation modelling (PLS-SEM) was used to examine the relationship between these factors and the residents' support for future film tourism (RSFFT). The results indicate that place attachment and perceived importance of …

Blockchain And Sustainability Disclosure: A Scenario-Based Application For Supply Chains, Laura Corazza, Junru Zhang, Dilhani Kapu Arachchilage, Simone Domenico Scagnelli

Research outputs 2022 to 2026

This paper presents the implications of blockchain technologies on sustainability reporting and disclosure, and specifically proposes blockchain use-cases as a possible solution for problems experienced in the field of supply chain carbon information. This study addresses how the reliability of supply chains’ carbon-related information can become more transparent and reliable through a decentralized approach based on blockchain thinking (BT), issues that have been identified as a gap in the literature and in the practice. Scenario analysis and design science research (DSR) are used as a methodological driver to conceptualize over the nature of practical solutions using unified modeling language (UML) …

Forest Hydrology In Chile: Past, Present, And Future, Francisco Balocchi, Mauricio Galleguillos, Diego Rivera, Alejandra Stehr, Jose Luis Arumi, Roberto Pizarro, Pablo Garcia-Chevesich, Andrés Iroumé, Juan J. Armesto, Pedro Hervé-Fernández, Carlos Oyarzún, Pilar Barría, Christian Little, Gabriel Mancilla, Santiago Yépez, Rolando Rodriguez, Don A. White, Richard P. Silberstein, Daniel G. Neary, Pablo Ramírez De Arellano

Research outputs 2022 to 2026

This paper reviews the current knowledge of hydrological processes in Chilean temperate forests which extend along western South America from latitude 29° S to 56 ° S. This geographic region includes a diverse range of natural and planted forests and a broad sweep of vegetation, edaphic, topographic, geologic, and climatic settings which create a unique natural laboratory. Many local communities, endangered freshwater ecosystems, and downstream economic activities in Chile rely on water flows from forested catchments. This review aims to (i) provide a comprehensive overview of Chilean forest hydrology, to (ii) review prior research in forest hydrology in Chile, and …

Intrusion Detection Based On Bidirectional Long Short-Term Memory With Attention Mechanism, Yongjie Yang, Shanshan Tu, Raja Hashim Ali, Hisham Alasmary, Muhammad Waqas, Muhammad Nouman Amjad

Research outputs 2022 to 2026

With the recent developments in the Internet of Things (IoT), the amount of data collected has expanded tremendously, resulting in a higher demand for data storage, computational capacity, and real-time processing capabilities. Cloud computing has traditionally played an important role in establishing IoT. However, fog computing has recently emerged as a new field complementing cloud computing due to its enhanced mobility, location awareness, heterogeneity, scalability, low latency, and geographic distribution. However, IoT networks are vulnerable to unwanted assaults because of their open and shared nature. As a result, various fog computing-based security models that protect IoT networks have been developed. …

Shale Wettability Characteristics Via Air/Brines And Air/Oil Contact Angles And Influence Of Controlling Factors: A Case Study Of Lower Indus Basin, Pakistan, Darya Khan Bhutto, Abdul Majeed Shar, Ghazanfer Raza Abbasi, Ubedullah Ansari

Research outputs 2022 to 2026

Wettability is the fundamental parameter that influences the productivity of hydrocarbon reservoirs. The knowledge of this regarding shale formation is yet inadequate; thus, detailed analysis is essential for successful development of such reservoirs. The Early Cretaceous Sembar formations in the Lower Indus Basin, Pakistan, is considered as the key target for energy exploration; however, it exhibits large uncertainties due to the lack of data availability. Sembar shales hold significant hydrocarbon volumes rich in organic content; however, prior to this, no comprehensive research has been conducted to quantify the wetting behavior of these shales. Thus, precise information about the wetting behavior …

The Prevalence Of Adverse Reactions Among Individuals With Three-Dose Covid-19 Vaccination, Yuying Wang, Yujie Zhang, Meng Zhang, Xiaoyu Zhang, Haibin Li, Youxin Wang, Wei Wang, Jianguang Ji, Lijuan Wu, Deqiang Zheng

Research outputs 2022 to 2026

Background: Considering the adverse reactions to vaccination against coronavirus disease 2019 (COVID-19), some people, particularly the elderly and those with underlying medical conditions, are hesitant to be vaccinated. This study aimed to explore the prevalence of adverse reactions and provide direct evidence of vaccine safety, mainly for the elderly and people with underlying medical conditions, to receive COVID-19 vaccination. Methods: From 1st March to 30th April 2022, we conducted an online survey of people who had completed three doses of COVID-19 vaccination by convenience sampling. Adverse reaction rates and 95% confidence intervals were calculated. In addition, conditional logistic regression was …

Does Fatigue Influence Joint-Specific Work And Ground Force Production During The First Steps Of Maximal Acceleration?, Shayne Vial, Jodie C. Wilkie, Mitchell Turner, Mark Scanlan, Anthony J. Blazevich

Research outputs 2022 to 2026

During initial acceleration, the first steps of a maximal-effort (sprint) run often determine success or failure in the capture and evasion of an opponent, and is therefore a vital factor of success in many modern sports. However, accelerative events are commonly performed after having already run considerable distances, and the associated fatigue should impair muscle force production and thus reduce acceleration. Despite this, the effects of running-induced fatigue on our ability to accelerate as well as the running technique used to achieve it have received little attention. We recorded 3-D kinematics and ground reaction forces during the first three steps …

Genetic Analysis Of Heterogeneous Subsets Of Circulating Tumour Cells From High Grade Serous Ovarian Carcinoma Patients, Du-Bois Asante, Ganendra R. K. A. Mohan, Emmanuel Acheampong, Mel R. Ziman Dr, Leslie Calapre, Tarek M. Meniawy, Elin S. Gray, Aaron B. Beasley

Research outputs 2022 to 2026

Circulating tumour cells (CTCs) are heterogenous and contain genetic information from the tumour of origin. They bear specific intra- and extra-cellular protein markers aiding in their detection. However, since these markers may be shared with other rare cells in the blood, only genetic testing can confirm their malignancy. Herein, we analyse different CTC subsets using single cell whole genome DNA sequencing to validate their malignant origin. We randomly selected putative CTCs identified by immunostaining that were isolated from 4 patients with high grade serous ovarian cancer (HGSOC) and one with benign cystadenoma. We specifically targeted CTCs positive for epithelial (CK/EpCAM …

Green Human Resource Management And Employee Innovative Behaviour: Does Inclusive Leadership Play A Role?, Azadeh Shafaei, Mehran Nejati

Research outputs 2022 to 2026

Purpose: This study examines the relationship between green human resource management (green HRM) and employee innovative behaviour. It also investigates the mediating role of job satisfaction to explore the mechanism through which green HRM is related to employee innovative behaviour. Additionally, it examines the moderating role of inclusive leadership to determine the boundary condition of the relationship between green HRM and employee innovative behaviour. Design/methodology/approach: The study used a quantitative research approach using survey and collected 508 responses from full-time employees in Australia. Findings: The authors have found support for all the hypothesised relationships in the study. Specifically, green HRM …

Gestational Age At Birth And Body Size From Infancy Through Adolescence: An Individual Participant Data Meta-Analysis On 253,810 Singletons In 16 Birth Cohort Studies, Johan L. Vinther, Tim Cadman, Demetris Avraam, Claus T. Ekstrøm, Thorkild I. A. Sørensen, Ahmed Elhakeem, Ana C. Santos, Angela Pinot De Moira, Barbara Heude, Carmen Iñiguez, Costanza Pizzi, Elinor Simons, Ellis Voerman, Eva Corpeleijn, Faryal Zariouh, Gilian Santorelli, Hazel M. Inskip, Henrique Barros, Jennie Carson, Jennifer R. Harris, Johanna L. Nader, Justiina Ronkainen, Katrine Strandberg-Larsen, Loreto Santa-Marina, Lucinda Calas, Luise Cederkvist, Maja Popovic, Marie-Aline Charles, Marieke Welten, Martine Vrijheid, Meghan Azad, Padmaja Subbarao, Paul Burton, Puishkumar J. Mandhane, Rae Chi Huang, Rebecca C. Wilson, Sido Haakma, Sílvia Fernández-Barrés, Stuart Turvey, Susana Santos, Suzanne C. Tough, Sylvain Sebert, Theo J. Moraes, Theodosia Salika, Vincent W. V. Jaddoe, Deborah A. Lawlor, Anne-Marie Nybo Andersen

Research outputs 2022 to 2026

Background:

Preterm birth is the leading cause of perinatal morbidity and mortality and is associated with adverse developmental and long-term health outcomes, including several cardiometabolic risk factors and outcomes. However, evidence about the association of preterm birth with later body size derives mainly from studies using birth weight as a proxy of prematurity rather than an actual length of gestation. We investigated the association of gestational age (GA) at birth with body size from infancy through adolescence.

Methods and Findings:

We conducted a two-stage individual participant data (IPD) meta-analysis using data from 253,810 mother-child dyads from 16 general population-based cohort …

Partially Oxidative Torrefaction Of Woody Biomass Pellets: Burning Behaviour And Emission Analysis, Sajid Riaz, Yasir M. Al-Abdeli, Ibukun Oluwoye

Research outputs 2022 to 2026

Non-conventional torrefaction under partially oxidative conditions is an emerging cost-effective thermochemical pre-treatment method to improve the quality of biomass for energy applications. The literature lacks data on the combustion of biomass torrefied under oxygen-deficient atmosphere with actual reactor conditions (inevitable non-uniformities in the thermal environment). In this work, a dual mode fixed-bed biomass (torrefaction) reactor and combustor was operated on Australian biomass pellets, to torrefy the fuels at 275 °C for 30 min using partially oxidative atmosphere (O₂: 5 vol %, balance N₂) and then to combust them. Combustion behaviour with a particular focus on gaseous …

Effect Of 3d Printing Parameters On The Fatigue Properties Of Parts Manufactured By Fused Filament Fabrication: A Review, Hamed Bakhtiari, Muhammad Aamir, Majid Tolouei-Rad

Research outputs 2022 to 2026

The advancement in 3D printing techniques has raised the hope to use additively manufactured parts as final products in various industries. However, due to the layer-by-layer nature of AM parts, they are highly susceptible to failure when they are subjected to fatigue loading. This review provides a detailed account of the influence of 3D printing parameters on the fatigue properties of parts manufactured by fused filament fabrication (FFF). Existing standards for fatigue testing of polymers and their limitation for 3D-printed parts are discussed. In addition, the cyclic behaviour of polymers is reviewed, and the impact of 3D printing parameters on …

Multivariate Cross-Validation And Measures Of Accuracy And Precision, Ute Mueller, Sangga Rima Roman Selia, Raimon Tolosana-Delgado

Research outputs 2022 to 2026

Cross-validation and performance measures are standard components in the evaluation of a geostatistical model. These are well established in the univariate case, but measures for multivariate geostatistical modeling have not received as much attention. In the case of a single target variable, the univariate approaches remain valid, but in the fully multivariate case where a vector of variables needs to be estimated, the evaluation needs to be based on all estimates simultaneously. An extension of cross-validation and associated performance measures to the fully multivariate case is presented and discussed for the case of regionalized compositions. The method is demonstrated by …

Plant Proteomic Research 5.0: From Data To Insights, Setsuko Komatsu, Michelle L. Colgrave

Research outputs 2022 to 2026

Proteomics offers one of the best approaches for the functional analysis of the genome, generating detailed information that can be integrated with that obtained by other classic and omics approaches. It, thus, provides deep knowledge and an understanding of diverse proteoforms and different plant processes. Several different generations of proteomic platforms have appeared in the past 25 years. They have been exploited for describing protein profiles, post-translational modifications, and subcellular localization. Despite recent advancements, more emphasis needs to be given to the protein sample preparation protocols, especially for cases with very low abundance, hydrophobicity, and a large molecular weight. The …

Skin-Derived Abcb5+ Mesenchymal Stem Cells For High-Medical-Need Inflammatory Diseases: From Discovery To Entering Clinical Routine, Elke Niebergall-Roth, Natasha Y. Frank, Christoph Ganss, Markus H. Frank, Mark A. Kluth

Research outputs 2022 to 2026

The ATP-binding cassette superfamily member ABCB5 identifies a subset of skin-resident mesenchymal stem cells (MSCs) that exhibit potent immunomodulatory and wound healing-promoting capacities along with superior homing ability. The ABCB5+ MSCs can be easily accessed from discarded skin samples, expanded, and delivered as a highly homogenous medicinal product with standardized potency. A range of preclinical studies has suggested therapeutic efficacy of ABCB5+ MSCs in a variety of currently uncurable skin and non-skin inflammatory diseases, which has been substantiated thus far by distinct clinical trials in chronic skin wounds or recessive dystrophic epidermolysis bullosa. Therefore, skin-derived ABCB5+ MSCs have the potential …

The Benefits To Bone Health In Children And Pre-School Children With Additional Exercise Interventions: A Systematic Review And Meta-Analysis, Callum Mccaskie, Aris Siafarikas, Jodie Cochrane Wilkie, Vanessa Sutton, Paola Chivers, Nicolas H. Hart, Myles C. Murphy

Research outputs 2022 to 2026

Objective: Determine if exercise interventions, beyond what is already provided to children and preschool children, improve bone health and reduce fracture incidence. Design: Systematic review and meta-analysis reported using the PRISMA guidelines. Certainty of evidence was assessed using GRADE recommendations. Data sources: Five electronic databases were searched for records: PUBMED; CINAHL; CENTRAL; SPORTDiscus; Web of Science. Eligibility criteria for selecting studies: Randomised, quasi-randomised and non-randomised controlled trials (including cluster-randomised) assessing the impact of additional exercise interventions (e.g., increased physical education classes or specific jumping programs) on bone health in children (6 – 12 years) and pre-school children (2 – 5 …

Using Magnesium Oxide Nanoparticles In A Magnetic Field To Enhance Oil Production From Oil-Wet Carbonate Reservoirs, F. Amrouche, M. J. Blunt, Stefan Iglauer, M. Short, T. Crosbie, E. Cordero, D. Xu

Research outputs 2022 to 2026

Enhanced oil production can maximise yield from depleted reservoirs, and in the face of dwindling global oil reserves can reduce the need for exploratory drilling during the transition away from fossil fuels. A hybrid technique, merging a magnetic field (MF) and magnesium oxide (MgO) nanoparticles (NPs), was investigated as a potential method of enhancing oil production from oil-wet carbonate reservoirs. The impact of this hybrid technique on rock wettability, zeta potential, and interfacial tension was also investigated. Displacement experiments were carried out on oil-wet Austin chalk – a laboratory carbonate rock analogue – using MgO NPs in deionized water (DW) …

Authentic Leadership And Psychological Well-Being Of Nurses: A Mediated Moderation Model, Stephen Teo, Andrei Lux, David Pick

Research outputs 2022 to 2026

Aims. This study investigates how authentic leadership influences the psychological well-being of Australian nurses. We examined whether authentic leadership could reduce the prevalence of workplace incivility and tested whether shared values and person-organization (P-O) fit could moderate the relationship between workplace incivility and psychological well-being (PWB). A mediated moderation model underpinned by social learning theory was developed to test the influence of authentic leadership on PWB.

Design. We adopted a descriptive correlational research design to test the hypothesized model with a cross-sectional sample of Australian nurses using an online survey. Data were collected across two-waves separated by a …

From Real Life To Story – And Back Again: Using Autobiographical Fiction Writing To Understand Self, Others And Family Generations, Alberta N. Adji

Research outputs 2022 to 2026

Writing autobiographically includes complicated responsibilities to the subjects involved: to family members, friends, colleagues, and even cultural communities. This article explores creative developments occurring during the process of writing an autobiographical novel called ‘The longing’, which is drawn from a recollection of intergenerational lived experiences of a middle-class Chinese Indonesian family from 1956 to 2018. I reflect on my strategies and approaches on tackling challenges that arose while using autobiographical material and autofictional techniques to write fiction and communicating cultural complexities for it allows agreeable distance between the author and her writing subject. In the article, I also argue that …

A Systematic Review Of Literature On Occupational Health And Safety Interventions For Older Workers, Tim Bentley, Leigh-Ann Onnis, Alexis Vassiley, Ben Farr-Wharton, Carlo Caponecchia, Catherine Andrew, Sharron O’Neill, Abilio De Almeida Neto, Vanessa Huron, Nicola Green

Research outputs 2022 to 2026

As the global population ages there is an imperative to enhance labour participation of older workers in ways that support good physical and psychological health. However, there is limited guidance for organisations on how to do this effectively. This systematic review examined literature identified through four databases and a targeted web-search, yielding 39 PRISMA records (32 scholarly, seven grey literature) reporting workplace interventions aimed at improving the injury outcomes of older workers. The review revealed that organisational and composite interventions may be most effective, although an absence of robust research in this area and a scarcity of empirical evidence-based interventions …