Digital Commons Network^™

Metabolomic Differences Between Invasive Alien Plants From Native And Invaded Habitats, Sarah A. Skubel, Xiaoyang Su, Alexander Poulev, Llewellyn C. Foxcroft, Vyacheslav Dushenkov, Ilya Raskin

Publications and Research

Globalization facilitated the spread of invasive alien species (IAS), undermining the stability of the world’s ecosystems. We investigated the metabolomic profiles of three IAS species: Chromolaena odorata (Asteraceae) Datura stramonium (Solanaceae), and Xanthium strumarium (Asteraceae), comparing metabolites of individual plants in their native habitats (USA), to their invasive counterparts growing in and around Kruger National Park (South Africa, ZA). Metabolomic samples were collected using RApid Metabolome Extraction and Storage (RAMES) technology, which immobilizes phytochemicals on glass fiber disks, reducing compound degradation, allowing long-term, storage and simplifying biochemical analysis. Metabolomic differences were analyzed using ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) of samples …

Medical Resource Use And Costs Of Treating Sickle Cell-Related Vaso-Occlusive Crisis Episodes: A Retrospective Claims Study, Nirmish Shah, Menaka Bhor, Lin Xie, Jincy Paulose, Huseyin Yuce

Publications and Research

Background: The study investigated the economic burden of vaso-occlusive crisis (VOC) among sickle cell disease (SCD) patients, through assessment of overall utilization and costs and costs per VOC episode (regarding the number of VOC episodes and health care setting, respectively).

Methods: Using the Medicaid Analytic Extracts database, the first SCD-related diagnosis claim (index claim) between June 1, 2009–December 31, 2012 was identified among eligible adults. Patients were required to have continuous medical and pharmacy benefits for 6 months pre- and 12 months post-index. Discrete VOC claims identified within a 3-day gap were combined as a single VOC episode. Annual all-cause …

Female Breast Cancer Mortality In Relation To Puberty On Staten Island, New York, Alfred M. Levine, Donna B. Gerstle

Publications and Research

Pursuant to a Congressional act in 2008, the Department of Health and Human Services established the Interagency Breast Cancer and Environmental Research Coordinating Committee to address the burden of breast cancer in the United States. Subsequently, the Committee recommended researchers study the timing of exposure to breast cancer risk factors. Given the high breast cancer mortality rate on Staten Island, this paper presents a case-control study investigating breast cancer risk associated with puberty while living on Staten Island. The dataset combined New York City Department of Health and Mental Hygiene female death certificate information between 1985 and 2006, with life …

Use, Perceptions, And Awareness Of Libguides Among Undergraduate And Graduate Health Professions Students, John Carey, Ajatshatru Pathak, Sarah C. Johnson

Publications and Research

Objective–This study investigated usage, perceptions, and awareness of library research guides created using Springshare’s LibGuides among undergraduate and graduate health professions students.

Methods–The researchers recruited 100 health professions students in April 2017 from Hunter College, a senior college within the City University of New York system. Participants were asked to complete a paper survey to ascertain their use, perceptions, and awareness of Springhare’s LibGuides.

Results–Nearly two-thirds of study participants were not aware of library-created LibGuides and 68% had never used this tool. Compared to undergraduates, graduate students were more likely to be aware of LibGuides. The use of LibGuides was …

Identification Of Tandem Repeat Families From Long-Read Sequences Of Humulus Lupulus, Katherine A. Easterling, Nicholi J. Pitra, Taylan B. Morcol, Jenna R. Aquino, Lauren G. Lopes, Kristin C. Bussey, Paul D. Matthews, Hank W. Bass

Publications and Research

Hop (Humulus lupulus L.) is known for its use as a bittering agent in beer and has a rich history of cultivation, beginning in Europe and now spanning the globe. There are five wild varieties worldwide, which may have been introgressed with cultivated varieties. As a dioecious species, its obligate outcrossing, non-Mendelian inheritance, and genomic structural variability have confounded directed breeding efforts. Consequently, understanding the hop genome represents a considerable challenge, requiring additional resources. In order to facilitate investigations into the transmission genetics of hop, we report here a tandem repeat discovery pipeline developed using k-mer filtering and dot plot …

Of Experts And Tokens: Mapping A Critical Race Archaeology Of Communication, Roopali Mukherjee

Publications and Research

A disgraceful white boys’ club persists within the field of Communication. Engaging key institutional structures and epistemic formations through which the field remains so white, this essay considers the mechanisms by which critical race and gender scholars are positioned as eternally foreign, always just arriving, to the field of communication. Addressing the implications of these “epistemologies of ignorance” on the development of the discipline, this essay outlines an intellectual and institutional archeology of Communication to reveal, instead, a field marked and shaped, from the start, by ethno-racial encounter. Communication, I suggest, remains so white because its experts and leaders continue …

Collaborative Assignments And Projects: Interdisciplinary Collaborative Assignments And Projects: Case Studies In Information Literacy And Higher Order Thinking Skills, Leslie Ward, Trikartikaningsih Byas, Alisa Cercone, Barbara L. Lynch, Kathleen Wentrack

Publications and Research

In their efforts to assist and enhance student learning, Queensborough’s faculty engages in developing and implementing various pedagogical innovations. One unique practice at Queensborough is Students Working in Interdisciplinary Groups (SWIG), a HIP that falls within the AAC&U designation of Collaborative Assignments and Projects, which incorporates collaboration with library faculty as an integral component to student learning. This chapter will explain the SWIG pedagogy and process, faculty collaboration with the QCC library, its replicable model, case studies, and assessment.

Librarians In Dissertation Deposit: Infusing An Institutional Ritual With Scholarly Communication Instruction, Roxanne Shirazi, Jill Cirasella

Publications and Research

Most doctoral students are required to produce a dissertation that makes an original contribution to their field of study in order to fulfill their degree requirements. The scholarly nature of this requirement informs how students and faculty approach doctoral research, but universities often treat the dissertations themselves merely as student records, not scholarly contributions. Librarians, however, are uniquely situated to work with graduate students as emerging participants in the scholarly communication ecosystem and help them prepare their dissertations for an outside audience. Librarians have the expertise to advise students with questions regarding copyright, licensing, fair use, and authors’ rights, as …

Sartorial Subversion: Eliza Haywood’S Fantomina And The Literary Tradition Of Women’S Community, Ruth Garcia

Publications and Research

This article locates Fantomina in a literary tradition that proposes all-female communities, such as convents and monasteries, as liberating and empowering spaces. I argue that the novella implies a virtual community rather than an actual one, as the heroine collectively embodies many different women, all of distinct social ranks: the heroine is both one woman and a variety of women brought together under the auspices of a single body, much the way discrete individuals together compose a community. Then, too, Beauplaisir, the object of the heroine’s desire, treats all the personae the same, no matter their social station. This emphasis …

An Osteocalcin-Deficient Mouse Strain Without Endocrine Abnormalities, Cassandra R. Diegel, Steven Hann, Ugar M. Ayturk, Jennifer C. W. Hu, Kyungeun Lim, Casey J. Droscha, Zachary B. Madaj, Gabrielle E. Foxa, Isaac Izaguirre, Vai Vivarium And Transgenics Core, Noorulain Paracha, Bohdan Pidhaynyy, Terry L. Dowd, Alexandra G. Robling, Matthew L. Warman, Bart O. Williams

Publications and Research

Osteocalcin (OCN), the most abundant noncollagenous protein in the bone matrix, is reported to be a bone-derived endocrine hormone with wide-ranging effects on many aspects of physiology, including glucose metabolism and male fertility. Many of these observations were made using an OCN-deficient mouse allele (Osc– ) in which the 2 OCN-encoding genes in mice, Bglap and Bglap2, were deleted in ES cells by homologous recombination. Here we describe mice with a new Bglap and Bglap2 double-knockout (dko) allele (Bglap/2p.Pro25fs17Ter) that was generated by CRISPR/Cas9-mediated gene editing. Mice homozygous for this new allele do not express full-length Bglap or Bglap2 mRNA …

Challenges In Quantifying Air‐Water Carbon Dioxide Flux Using Estuarine Water Quality Data: Case Study For Chesapeake Bay, Maria Herrmann, Raymond G. Najjar, Fei Da, Jaclyn R. Friedman, Marjorie A. M. Friedrichs, Sreece Goldberger, Alana Menendez, Elizabeth H. Shadwick, Edward G. Stets, Pierre St-Laurent

Publications and Research

Estuaries play an uncertain but potentially important role in the global carbon cycle via CO₂ outgassing. The uncertainty mainly stems from the paucity of studies that document the full spatial and temporal variability of estuarine surface water partial pressure of carbon dioxide ( pCO₂). Here, we explore the potential of utilizing the abundance of pH data from historical water quality monitoring programs to fill the data void via a case study of the mainstem Chesapeake Bay (eastern United States). We calculate pCO₂ and the air-water CO₂ flux at monthly resolution from 1998 to …

A Role For Retinoids In The Treatment Of Covid-19?, Steven E. Trasino

Publications and Research

The 2020 global outbreak of the novel coronavirus (SARS-CoV-2 or COVID-19) is a serious threat to international health, and thus, there is an urgent need for discoverynof novel therapies or use of repurposed drugs that can make a significant impact on slowing the spread of the virus. Type 1 interferons (IFN-I) are a family cytokines of the early innate immune response to viruses that are being tested against SARSCoV- 2. However, coronaviruses similar to SARS-CoV-2 can suppress host IFN-I antiviral responses. Retinoids are a family molecules related to vitamin A that possess robust immune-modulating properties, including the ability to increase …

Studying Public Perception About Vaccination: A Sentiment Analysis Of Tweets, Viju Raghupathi, Jie Ren, Wullianallur Raghupathi

Publications and Research

Text analysis has been used by scholars to research attitudes toward vaccination and is particularly timely due to the rise of medical misinformation via social media. This study uses a sample of 9581 vaccine-related tweets in the period 1 January 2019 to 5 April 2019. The time period is of the essence because during this time, a measles outbreak was prevalent throughout the United States and a public debate was raging. Sentiment analysis is applied to the sample, clustering the data into topics using the term frequency–inverse document frequency (TF-IDF) technique. The analyses suggest that most (about 77%) of the …

Snapshots Of Human Anatomy, Locomotion, And Behavior From Late Pleistocene Footprints At Engare Sero, Tanzania, Kevin Hatala, William E. H. Harcourt-Smith, Adam D. Gordon, Brian W. Zimmer, Brian G. Richmond, Briana L. Pobiner, David J. Green, Adam Metallo, Vince Rossi, Cynthia M. Liutkus-Pierce

Publications and Research

Fossil hominin footprints preserve data on a remarkably short time scale compared to most other fossil evidence, offering snapshots of organisms in their immediate ecological and behavioral contexts. Here, we report on our excavations and analyses of more than 400 Late Pleistocene human footprints from Engare Sero, Tanzania. The site represents the largest assemblage of footprints currently known from the human fossil record in Africa. Speed estimates show that the trackways reflect both walking and running behaviors. Estimates of group composition suggest that these footprints were made by a mixed-sex and mixed-age group, but one that consisted of mostly adult …

Healthcare Expenditure And Economic Performance: Insights From The United States Data, Viju Raghupathi, Wullianallur Raghupathi

Publications and Research

This research explores the association of public health expenditure with economic performance across the United States. Healthcare expenditure can result in better provision of health opportunities, which can strengthen human capital and improve the productivity, thereby contributing to economic performance. It is therefore important to assess the phenomenon of healthcare spending in a country. Using visual analytics, we collected economic and health data from the Bureau of Economic Analysis and the Bureau of Labor Statistics for the years 2003–2014. The overall results strongly suggest a positive correlation between healthcare expenditure and the economic indicators of income, GDP, and labor productivity. …

Pain Management: Genetic Basis For Racial Disparities?, Brittany Taylor

Publications and Research

No abstract provided.

Redefining Gender & Gender Expression Through Self-Perceptions & Self-Reflections, Deborah O. Ade

Publications and Research

As societies evolve policies are developed to recognize and formalize these changes. One current context for change is New York City and the concept that has undergone significant change is gender. Many individuals no longer identify with the traditional binary distinction of male or female. Subsequently, new gender categories have emerged (e.g., bi-gender, pan gender, androgynous). Indeed, a total of 31 gender categories have been recognized by the NYC Commission of Human Rights. The goal behind this acknowledgement is to encourage equitable treatment and respect of all individuals within the workplace. NYC businesses that do not accommodate individuals identifying with …

Taking A Closer Look On The Coronavirus, Alisha Barday, Janina Duran, Lisa Agranov

Publications and Research

No abstract provided.

A National Prospective Cohort Study Of Sars/Cov2 Pandemic Outcomes In The U.S.: The Chasing Covid Cohort, Mckaylee Robertson, Sarah Kulkarni, Amanda Berry, Chloe Mirzayi, Andrew Maroko, Rebecca Zimba, Drew Westmoreland, Christina Grov, Angela Parcesepe, Levi Waldron, Denis Nash

Publications and Research

Introduction: The Chasing COVID Cohort (C 3 ) study is a US-based, geographically and socio-demographically diverse sample of adults (18 and older) enrolled into a prospective cohort study during the upswing of the U.S. COVID-19 pandemic.

Methods: We used internet-based strategies to enroll C 3 participants beginning March 28th, 2020. Following baseline questionnaire completion, study participants will be contacted monthly (for 6 months) to complete assessments of engagement in non-pharmaceutical interventions (e.g., use of cloth masks, avoiding large gatherings); COVID-19 symptoms; SARS/COV2 testing and diagnosis; hospitalizations; healthcare access; and uptake of health messaging. Dried blood spot (DBS) specimens will be …

Playing Slavery In First Grade: When “Developmental Appropriateness” Goes Awry In The Progressive Classroom, Debbie Sonu

Publications and Research

This article unfurls in the aftermath of an event where three first grade children at a reputable progressive elementary school were found playing slavery during school recess. As word caught on, parents ignited into a frenzy: some railed against the teacher, others demanded an answer, while still others believed this was precisely the meaning of progressive schooling. In swift response, school administrators sent a conciliatory email apologizing for their misjudgment. Slavery, they declared, was too difficult a topic and developmentally inappropriate for such a young age. Guided by critical childhood studies and concepts of difficult knowledge, this reflective article explores …

Making Racial Difference: A Foucauldian Analysis Of School Memories Told By Undergraduates Of Color In The United States, Debbie Sonu

Publications and Research

This paper draws from the writings of Michel Foucault and his recently reconsidered provocations on race and racialization. Using Foucault’s de!nition of ‘internal racism,’ race is understood as a complex set of correlations that are employed for the purpose of establishing (ab)normality and exercising various forms of expul- sion. Racialization is then seen as the circulation of knowledge that makes racial categorization evident as scienti!c truth, linked to themes of science, developmentality, and the governing of popula- tion. To illustrate its subjective materialization, I analyze childhood memories of school told by undergraduates of color at one large public university in …

A Single, Narrowly Focused Create Primary Literature Module Evokes Gains In Genetics Students’ Self-Efficacy And Understanding Of The Research Process, Alison Krufka, Kristy Kenyon, Sally G. Hoskins

Publications and Research

Exposure to primary literature using CREATE tools has been shown to have a positive impact on students’ self-efficacy and beliefs when incorporated into semester-long courses taught by extensively trained faculty. However, it is unknown whether similar benefits can occur with a brief exposure to CREATE in an otherwise traditionally taught course. We hypothesized that students who experienced a short-term CREATE module taught by faculty with minimal training in this pedagogy would make gains in scientific literacy and self-efficacy while also experiencing epistemological maturation. To test this hypothesis, we compared sections of students who experienced the CREATE module with sections of …

Otx2 Represses Sister Cell Fate Choices In The Developing Retina To Promote Photoreceptor Specification, Miruna Georgiana Ghinia Tegla, Diego F. Buenaventura, Diana Y. Kim, Cassandra Thakurdin, Kevin C. Gonzalez, Mark M. Emerson

Publications and Research

During vertebrate retinal development, subsets of progenitor cells generate progeny in a non-stochastic manner, suggesting that these decisions are tightly regulated. However, the gene-regulatory network components that are functionally important in these progenitor cells are largely unknown. Here we identify a functional role for the OTX2 transcription factor in this process. CRISPR/Cas9 gene editing was used to produce somatic mutations of OTX2 in the chick retina and identified similar phenotypes to those observed in human patients. Single cell RNA sequencing was used to determine the functional consequences OTX2 gene editing on the population of cells derived from OTX2-expressing retinal progenitor …

In Vivo Data: Treatment With The F11r/Jam-A Peptide 4d Decreases Mortality And Reduces The Generation Of Atherosclerotic Plaques In Apoe-Deficient Mice, Anna Babinska, Cristina C. Clement, Yan Li, Joanna Wzorek, Tomasz Przygodzki, Marcin Talar, Marcin Braun, Maria Swiatkowska, Yigal H. Ehrlich, Elizabeth Kornecki, Cezary Watala, Moro O. Salifu

Publications and Research

The data in this article focus on the F11 Receptor (F11R/JAM-A; Junctional Adhesion Molecule-A; JAM-A, F11R), a cell adhesion protein constitutively expressed on the membrane surface of circulating platelets and localized within the tight junctions of healthy endothelial cells (ECs). Previous reports have shown that F11R/JAM-A plays a critical role in the adhesion of platelets to an inflamed endothelium due to its’ pathological expression on the luminal surface of the cytokine-inflamed endothelium. Since platelet adhesion to an inflamed endothelium is an early step in the development of atherosclerotic plaque formation, and with time, resulting in heart attacks and stroke, we …

Greater Social Cohesion Is Associated With Lower Body Mass Index Among African American Adults, Adolfo G. Cuevas, Ichiro Kawachi, Kasim Ortiz, Mariam Pena, Lorraine R. Reitzel, Lorna H. Mcneill

Publications and Research

Obesity remains a public health issue, especially for Blacks (or African Americans). Obesity is thought to reflect a complex interaction of socioenvironmental, biological, and cognitive factors. Yet, insufficient attention has been given to psychosocial factors like social cohesion within the African American community. Using multivariable linear regression, we examined the association between social cohesion, measured by the Social Cohesion and Trust scale, and body mass index (BMI) with cross-sectional data (n = 1467) from a cohort study (2008–2009). Greater social cohesion was associated with lower BMI (b = -0.88; 95% CI: −1.45, −0.32) in an unadjusted model. The association was …

Transcranial Electrical Stimulation Motor Threshold Can Estimate Individualized Tdcs Dosage From Reverse-Calculation Electric-Field Modeling, Kevin A. Caulfield, Bashar W. Badran, William H. Devries, Philipp M. Summers, Emma Kofmehl, Xingbao Li, Jeffrey J. Borckardt, Marom Bikson, Mark S. George

Publications and Research

Background

Unique amongst brain stimulation tools, transcranial direct current stimulation (tDCS) currently lacks an easy or widely implemented method for individualizing dosage.

Objective

We developed a method of reverse-calculating electric-field (E-field) models based on Magnetic Resonance Imaging (MRI) scans that can estimate individualized tDCS dose. We also evaluated an MRI-free method of individualizing tDCS dose by measuring transcranial magnetic stimulation (TMS) motor threshold (MT) and single pulse, suprathreshold transcranial electrical stimulation (TES) MT and regressing it against E-field modeling. Key assumptions of reverse-calculation E-field modeling, including the size of region of interest (ROI) analysis and the linearity of multiple E-field …

Philosophical Perspectives, Jochen Albrecht

Publications and Research

This entry follows in the footsteps of Anselin’s famous 1989 NCGIA working paper entitled “What is special about spatial?” (a report that is very timely again in an age when non-spatial data scientists are ignorant of the special characteristics of spatial data), where he outlines three unrelated but fundamental characteristics of spatial data. In a similar vein, I am going to discuss some philosophical perspectives that are internally unrelated to each other and could warrant individual entries in this Body of Knowledge. The first one is the notions of space and time and how they have evolved in …

Efficacy Of Glutathione Therapy In Relieving Dyspnea Associated With Covid-19 Pneumonia: A Report Of 2 Cases, Richard I. Horowtiz, Phyllis R. Freeeman, James Bruzzese

Publications and Research

Purpose: Infection with COVID-19 potentially can result in severe outcomes and death from “cytokine storm syndrome”, resulting in novel coronavirus pneumonia (NCP) with severe dyspnea, acute respiratory distress syndrome (ARDS), fulminant myocarditis and multiorgan dysfunction with or without disseminated intravascular coagulation. No published treatment to date has been shown to adequately control the inflammation and respiratory symptoms associated with COVID-19, apart from oxygen therapy and assisted ventilation. We evaluated the effects of using high dose oral and/or IV glutathione in the treatment of 2 patients with dyspnea secondary to COVID-19 pneumonia.

Methods: Two patients living in New York City …

Combating Sars-Cov-2: Leveraging Microbicidal Experiences With Other Emerging/Re-Emerging Viruses, M. Khalid Ijaz, Syed A. Sattar, Joseph R. Rubino, Raymond W. Nims, Charles P. Gerba

Publications and Research

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan City, China, late in December 2019 is another example of an emerging zoonotic virus that threatens public health and international travel and commerce. When such a virus emerges, there is often insufficient specific information available on mechanisms of virus dissemination from animal to human or from person to person, on the level or route of infection transmissibility or of viral release in body secretions/excretions, and on the survival of virus in aerosols or on surfaces. The effectiveness of available virucidal agents and hygiene practices as interventions for disrupting …

Investigation Of An Elevational Gradient Reveals Strong Differences Between Bacterial And Eukaryotic Communities Coinhabiting Nepenthes Phytotelmata, Kadeem J. Gilbert, Leonora S. Bittleston, Mark Arcebal K. Naive, Anthony E. Kiszewski, Perry Archival C. Buenavente, David J. Lohman, Naomi E. Pierce

Publications and Research

Elevation is an important determinant of ecological community composition. It integrates several abiotic features and leads to strong, repeatable patterns of community structure, including changes in the abundance and richness of numerous taxa. However, the influence of elevational gradients on microbes is understudied relative to plants and animals. To compare the influence of elevation on multiple taxa simultaneously, we sampled phytotelm communities within a tropical pitcher plant (Nepenthes mindanaoensis) along a gradient from 400 to 1200 m a.s.l. We use a combination of metabarcoding and physical counts to assess diversity and richness of bacteria, micro-eukaryotes, and arthropods, and compare the …