Digital Commons Network^™

Salmoniformes (Salmons), Aldemaro Romero Jr.

Publications and Research

No abstract provided.

One Eye But No Vision: Troglomorphic Astyanax Fasciatus (Pisces: Characidae) With Induced Eyes Do Not Respond To Light, Aldemaro Romero Jr., Steven M. Green, Andrea Romero, Megan M. Lelonek, Katy C. Stropnicky

Publications and Research

No abstract provided.

Significance Of Two Distinct Types Of Tryptophan Synthase Beta Chain In Bacteria, Archaea And Higher Plants, Gary Xie, Christian Forst, Carol Bonner, Roy A. Jensen

Publications and Research

Tryptophan synthase consists of two subunits, α and β. Two subgroups of β chain exist; the major group TrpEb_1 and the minor group, TrpEb_2. Conserved amino-acid residues of TrpEb_1 that make allosteric contact with the TrpEa subunit (the α chain) are absent in TrpEb_2. Representatives of Archaea, Bacteria and higher plants all exist that possess both TrpEb_1 and TrpEb_2. at least six lineages of the Archaea are likely to use TrpEb_2 as the functional β chain.

Bioorganic Studies In Aids: Synthetic Antifungals Against Pneumocystis Carinii Based On The Multivalency Concept, Langu Peng, Cunxiang Chen, Christian R. Gonzalez, Valeria Balogh-Nair

Publications and Research

We report the syntheses of antifungals containing the novel pharmacophores: oxaziridines, sulfonyloxaziridines, nitrones and nitronyl nitroxides. We hypothesized that multiple copies of the pharmacophore per molecule might be a prerequisite to enhance efficacy against the opportunistic pathogen, Pneumocystis carinii. Therefore structural optimization of the leads was based on this new “multivalency” approach. All bisoxaziridines were inactive, but a trisoxaziridine caused ca. 50% reduction of the number of P. carinii tropozoites, compared to TMP-SMX, and a hexaoxaziridine at 1 µg/ml showed activity comparable to the currently used drug, TMP-SMX. Insertion of three units of the nitronyl nitroxide pharmacophore per molecule afforded …

Laboratory Response To Anthrax Bioterrorism, New York City, 2001, Michael B. Heller, Michel L. Bunning, Martin E.B. France, Debra M. Niemeyer, Leonard Peruski, Tim Naimi, Phillip M. Talboy, Patrick H. Murray, Harald W. Pietz, John Kornblum, William Oleszko, Sara T. Beatrice, Joint Microbiological Rapid Response Team, New York City Anthrax Investigation Working Group, Denis Nash

Publications and Research

In October 2001, the greater New York City Metropolitan Area was the scene of a bioterrorism attack. The scale of the public response to this attack was not foreseen and threatened to overwhelm the Bioterrorism Response Laboratory’s (BTRL) ability to process and test environmental samples. In a joint effort with the Centers for Disease Control and Prevention and the cooperation of the Department of Defense, a massive effort was launched to maintain and sustain the laboratory response and return test results in a timely fashion. This effort was largely successful. The development and expansion of the facility are described, as …

The Source Of Hip, Shelly J. Eversley

Publications and Research

This essay situates Norman Mailer's "The White Negro" (1957) and Jack Keroauc's The Subterraneans (1958) in the context of 1950s racial integration and the transformative potential of interracial sex. It argues that both authors' terms, "beat" and "hip," depend on the idea of "the Negro" whose status allows them to imagine a counter culture essential to their midcentury articulations of individual integrity and creative freedom.

Dynamic Diversity Of The Tryptophan Pathway In Chlamydiae: Reductive Evolution And A Novel Operon For Tryptophan Recapture, Gary Xie, Carol A. Bonner, Roy A. Jensen

Publications and Research

The factors that accommodate the transition of different chlamydial species to the persistent state of pathogenesis include marked differences in the strategied deplyed to obtain tryptophan from host resources. Chlamydia psittaci appears to have a novel mechanism for intercepting an early intermediate of tryptophan catabolism and recycling it back to tryptophan.

D1 Dopamine Receptor Regulation Of Microtubule-Associated Protein-2 Phosphorylation In Developing Cerebral Cortical Neurons, Z.-M. Song, Ashiwel S. Undieh, Y.-Y. Fang, L. Zhang, S. Dracheva, S.C. Sealfon, M.S. Lidow

Publications and Research

This study addresses the hypothesis that the previously described capacity of D1 dopamine receptors (D1Rs) to regulate dendritic growth in developing cortical neurons may involve alterations in the phosphorylation state of microtubuleassociated protein-2 (MAP2). The changes in phosphorylation of this protein are known to affect its ability to stabilize the dendritic cytoskeleton. The study involved two systems: primary cultures of mouse cortical neurons grown in the presence of the D1R agonists, SKF82958 or A77636, and the cortex of neonatal transgenic mice overexpressing the D1A subtype of D1R. In both models, a decrease in dendritic extension corresponded with an elevation in …

Low Concentration Microenvironments Enhance The Migration Of Neonatal Cells Of Glial Lineage, Richard A. Able, Jr., Celestin Ngnabeuye, Cade Beck, Eric C. Holland, Maribel Vazquez

Publications and Research

Glial tumors have demonstrated abilities to sustain growth via recruitment of glial progenitor cells (GPCs), which is believed to be driven by chemotactic cues. Previous studies have illustrated that mouse GPCs of different genetic backgrounds are able to replicate the dispersion pattern seen in the human disease. How GPCs with genetic backgrounds transformed by tumor paracrine signaling respond to extracellular cues via migration is largely unexplored, and remains a limiting factor in utilizing GPCs as therapeutic targets. In this study, we utilized a microfluidic device to examine the chemotaxis of three genetically-altered mouse GPC populations towards tumor conditioned media, as …

First Recipients Of Anthropological Doctorates In The United States, 1891-1930, Jay H. Bernstein

Publications and Research

This article seeks to show the origins of the professionalization of anthropology by examining early doctoral dissertations in this field and their authors. The bibliography consists of citations with biographical details of the authors, when known, of doctoral dissertations in anthropology from United States educational institutions up to 1930. One hundred twenty-four citations are given in all, representing 18 institutions. Forty-one of the dissertations were not written for degrees in anthropology. Besides documenting the existence of anthropological work outside recognized graduate programs of anthropology, the bibliography provides a demographic profile of anthropology and shows the distribution of subdiscipline concentrations and …

Nature And Nurture In Cognition, Muhammad Ali Khalidi

Publications and Research

This paper advocates a dispositional account of innate cognitive capacities, which has an illustrious history from Plato to Chomsky. The ‘triggering model’ of innateness, first made explicit by Stich ([1975]), explicates the notion in terms of the relative informational content of the stimulus (input) and the competence (output). The advantage of this model of innateness is that it does not make a problematic reference to normal conditions and avoids relativizing innate traits to specific populations, as biological models of innateness are forced to do. Relativization can be avoided in the case of cognitive capacities precisely because informational content is involved. …

Timing Of New Black Box Warnings And Withdrawals For Prescription Medications, Karen Lasser, Paul D. Allen, Steffie Woolhandler, David U. Himmelstein, Sidney M. Wolfe, David H. Bor

Publications and Research

Context Recently approved drugs may be more likely to have unrecognized adverse drug reactions (ADRs) than established drugs, but no recent studies have examined how frequently postmarketing surveillance identifies important ADRs.

Objective To determine the frequency and timing of discovery of new ADRs described in black box warnings or necessitating withdrawal of the drug from the market.

Design and Setting Examination of the Physicians' Desk Reference for all new chemical entities approved by the US Food and Drug Administration between 1975 and 1999, and all drugs withdrawn from the market between 1975 and 2000 (with or without a prior black …

Rio+10: Indigenous Peoples, Transnational Corporations, And Sustainable Development In Amazonia, Judith Kimerling

Publications and Research

No abstract provided.

Between The First Blind Cave Fish And The Last Of The Mohicans: The Scientific Romanticism Of James E. Dekay, Aldemaro Romero Jr.

Publications and Research

No abstract provided.

Writing An Important Body Of Scholarship: A Proposal For An Embodied Rhetoric Of Professional Practice, Jane Hindman

Publications and Research

Identifies a set of professional discursive practices of rhetoric teachers that reveal gendered power relations. Proposes an "embodied rhetoric" characterized and authorized in part by specific sorts of personal author- and context-saturated gestures. Concludes that an embodied rhetoric regenders academic discourse, assures agency and power to feminist theory and praxis, and facilitates efforts to effect change in teachers and students' lives.

Combinatorial Chemistry: A Guide For Librarians, Philip Barnett

Publications and Research

No abstract provided.

An Interview With Sandra Harding, Stephanie Urso Spina, Mike Roberts, Patricia Ticento Clough

Publications and Research

Harding’s position has been critiqued as more postmodern than feminist, as viable without nasty entanglements in feminism, as too concerned with established Eurocentric, scientific discourses, and as appealing to foundational innocence by her concern with realism. But what seems to drive Harding’s choices more than anything is a conscious attempt to be effective in intervening in existing systems of power, whether empiricist and postmodern. By taking this position, Harding undertakes a difficult task. Its difficulty, however, is compensated for by the conversations she generates. As a voice not restricted to one intellectual school, Harding demands attention from many with opposing …

Affiliation Among Females In Wild Hamadryas Baboons (Papio Hamadryas Hamadryas), Larissa Swedell

Publications and Research

Previous studies of hamadryas baboons have described a “star-shaped” sociogram, whereby the strongest social bonds within hamadryas one-male units are those between a leader male and his females and bonds among females are weak by comparison. This type of social organization has also been called “cross bonding” to distinguish it from the “female bonding” found in most papionin monkeys. Models of female primate socioecology have suggested that hamadryas baboons lack female bonding due to their reliance on scarce, widely-dispersed food resources. Here I report observational data from a wild population of hamadryas baboons in Ethiopia indicating that, while females varied …

Ranging Behavior, Group Size, And Behavioral Flexibility In Ethiopian Hamadryas Baboons (Papio Hamadryas Hamadryas)., Larissa Swedell

Publications and Research

This study reports group size, home range size, daily path lengths, seasonal effects on ranging behavior and qualitative information on diet for a population of hamadryas baboons inhabiting the lowlands of the northern Rift Valley in central Ethiopia. The minimum home range size and daily path length for this population are similar to those reported for other populations of hamadryas baboons in Ethiopia and Saudi Arabia. Group sizes, however, are much larger than those in most other hamadryas populations for which published data are available. The large group sizes in this area may be related to the abundance of one …

The Lunatic's Fancy And The Work Of Art, Shelly J. Eversley

Publications and Research

No abstract provided.

Ipsilesional Biases In Saccades But Not Perception After Lesions Of The Human Inferior Parietal Lobule, Tony Ro, Chris Rorden, Jon Driver, Robert Rafal

Publications and Research

We examined the effects of chronic unilateral lesions to either the inferior parietal lobe, or to the dorsolateral prefrontal cortex including the frontal eye fields (FEFs), upon human visual perception and saccades in temporal-order-judgment (TOJ) tasks. Two visual events were presented on each trial, one in each hemifield at various stimulus onset asynchronies (SOAs). In the saccade task, patients moved their eyes to whichever stimulus attracted gaze first. In the perceptual-manual task, they pressed a button to indicate which stimulus was perceived first. Frontal patients showed appropriate TOJs for visual targets in both tasks. Parietal patients showed appropriate TOJs in …

Making Writing Matter: Using "The Personal" To Recover[Y] An Essential[Ist] Tension In Academic Discourse, Jane Hindman

Publications and Research

Considers how constructing a hopeful professional discourse requires substantial revision of current professional discursive practices. Notes that the search for local knowledge and a shared, more hopeful discourse has rekindled interest in the rhetorical as well as material authority of ideologies, in various forms of writing collected under the overdetermined rubric "the personal." (SG)

Orthologs And Paralogs - We Need To Get It Right, Roy A. Jensen

Publications and Research

A response to Homologuephobia, by Gregory A Petsko, Genome Biology 2001 2:comment1002.1-1002.2, to An apology for orthologs - or brave new memes by Eugene V Koonin, Genome Biology 2001, 2:comment1005.1-1005.2, and to Can sequence determine function? by John A Gerlt and Patricia C Babbitt, Genome Biology 2000, 1:reviews0005.1-0005.10.

The Emerging Periplasm-Localized Subclass Of Aroq Chorismate Mutases, Exemplified By Those From Salmonella Typhimurium And Pseudomonas Aeruginosa, David H. Calhoun, Carol A. Bonner, Wei Gu, Gary Xie, Roy A. Jensen

Publications and Research

Background Chorismate mutases of the AroQ homology class are widespread in the Bacteria and the Archaea. Many of these exist as domains that are fused with other aromatic-pathway catalytic domains. Among the monofunctional AroQ proteins, that from Erwinia herbicola was previously shown to have a cleavable signal peptide and located in the periplasmic compartment. Whether or not this might be unique to E. herbicola was unknown. Results The gene coding for the AroQ protein was cloned from Salmonella typhimurium, and the AroQ protein purified from both S. typhimurium and Pseudomonas aeruginosa was shown to have a periplasmic location. The periplasmic …

The Nature Of Nature: South Floridian Children And Their "Environmental Experience", Kristina Baines

Publications and Research

To investigate how schoolchildren in south Florida think about their natural environment, children were observed participating in several school-organized environmental field trips. Their attitudes about, interactions with and knowledge concerning various aspects of their natural environment were observed. This study explores how these children interpret natural phenomena using their cultural tools and focuses on the interpretation of commonly-observed responses to nature. Responses discussed include: the blurring of lines between the natural and non-natural, separation and binary thinking, and fear and aggression. Reference is made throughout the study to various theoretical frameworks, including cultural-ecological perspectives, ideas from structural anthropology and other …

A Distance Education Collaboration: The Learning Café Experience, Miriam B. Deutch, Beth Evans, Lori Scarlatos

Publications and Research

As distance education collaborations between high schools and colleges increase, there is a concern that little has been done to assess the quality and effectiveness of the resulting virtual courses (Carr & Young, 1999). Yet it is equally important to address or consider the many challenges and issues of the collaboration itself. How these issues are addressed will seriously impact the success of any college distance education project in collaboration with other institutions of learning, including K-12 schools, community centers, and private industry. This article is about collaboration issues between high schools and colleges. It focuses on what the developers …

The Effects Of Buffer And Temperature Feedback On The Oceanic Uptake Of Co2, Chuixiang Yi, Peng Gong, Ming Xu, Ye Qi

Publications and Research

The feedback between climate and carbon cycle systems is critical to the prediction of future CO₂ concentration in the atmosphere and the capacity of the oceans to take up CO₂ from the atmosphere. We calculated the magnitudes of the potential feedback between the increase of atmospheric CO₂ concentration, the carbonate chemistry of the oceans (via a buffer factor), and the global temperature. We find that the magnitude of the buffer feedback depends strongly on the level of the dissolved inorganic carbon (DIC) in the oceans and increases rapidly with the increase of the atmospheric CO …

"God Gave Us This Land:" The Ovahimba, The Proposed Epupa Dam, The Independent Namibian State, And Law And Development In Africa, Sidney Harring

Publications and Research

No abstract provided.

Our Children: Kids Of Queer Parents & Kids Who Are Queer: Looking At Sexual Minority Rights From A Different Perspective, Ruthann Robson

Publications and Research

No abstract provided.

International Standards In Ecuador's Amazon Oil Fields: The Privatization Of Environmental Law, Judith Kimerling

Publications and Research

No abstract provided.