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Articles 511 - 540 of 3082
Full-Text Articles in Entire DC Network
Changes In Histone H3 Acetylation On Lysine 9 Accompany Aβ 1-40 Overexpression In An Alzheimer’S Disease Yeast Model, Muna M. Hugais, Samantha N. Cobos, Seth A. Bennett, Jailene Paredes, Genevieve Foran, Mariana P. Torrente
Changes In Histone H3 Acetylation On Lysine 9 Accompany Aβ 1-40 Overexpression In An Alzheimer’S Disease Yeast Model, Muna M. Hugais, Samantha N. Cobos, Seth A. Bennett, Jailene Paredes, Genevieve Foran, Mariana P. Torrente
Publications and Research
Alzheimer’s Disease (AD), the most common type of dementia, is a neurodegenerative disease characterized by plaques of amyloid-beta (Aβ) peptides found in the cerebral cortex of the brain. The pathological mechanism by which Aβ aggregation leads to neurodegeneration remains unknown. Interestingly, genetic mutations do not explain most AD cases suggesting that other mechanisms are at play. Epigenetic mechanisms, such as histone post-translational modifications (PTMs), may provide insight into the development of AD. Here, we exploit a yeast Aβ overexpression model to map out the histone PTM landscape associated with AD. We find a modest decrease in the acetylation levels on …
An Examination Of Coping Strategies And Intent To Leave Child Welfare During The Covid 19 Pandemic, Francie J. Julien‑Chinn, Colleen C. Katz, Eden Wall
An Examination Of Coping Strategies And Intent To Leave Child Welfare During The Covid 19 Pandemic, Francie J. Julien‑Chinn, Colleen C. Katz, Eden Wall
Publications and Research
Child welfare work is inherently difficult, and child welfare agencies are known to experience high rates of turnover. We sought to expand the existing literature on intention to leave one’s child welfare agency and commitment to child welfare work through examining the coping mechanisms of frontline workers. Having and utilizing healthy coping mechanisms has proved beneficial to child welfare workers in previous research. In this paper, we examine specific coping mechanisms identifed in the Comprehensive Organizational Health Assessment and how they were associated with child welfare workers’ intent to leave their agency and their commitment to remain in the field …
Vhs Archives, Committed Media Praxis, And ‘Queer Cinema', Alexandra Juhasz
Vhs Archives, Committed Media Praxis, And ‘Queer Cinema', Alexandra Juhasz
Publications and Research
Committed media praxis is a doing as much as it is a knowing. Queerness is a manner of being as much as it is a politics, theory, or set of modish objects. This chapter about topics that are also processes—queer, media praxis, cinema—performs these across two acts: “Part 1: A Hesitant or Maybe Just Slightly Defiant Preamble,” is a creative unfolding, in the body of the text and as much so in its footnotes, of the author’s “queer feminist media praxis”: “Part 2: VHS Archives” is a demonstration of VHS Archives, a multi-sited, many-yeared project in experimental pedagogy, web-based archival …
Connection Failure: War, Spiritualism And Communications Media In Violet Hunt's "Love's Last Leave.", Melissa Dinsman, Heather M. Robinson
Connection Failure: War, Spiritualism And Communications Media In Violet Hunt's "Love's Last Leave.", Melissa Dinsman, Heather M. Robinson
Publications and Research
An overlooked figure of modernist circles, Violent Hunt was a suffragette, novelist, and author of ghost stories. In her second collection of haunted narratives, More Tales of The Uneasy (1925), Hunt explores the ghostliness of the Great War, both for those on the front and at home. In this essay, we focus on the third story in this volume, “Love’s Last Leave,” and argue that Hunt includes both ghost story tropes and communications media to articulate the real deadliness of the Great War. Communications technology and spiritualism share a similar historical evolution, and in “Love’s Last Leave” both types …
A Review Of Camera Scanning Apps For You And Your Patrons, John P. Delooper
A Review Of Camera Scanning Apps For You And Your Patrons, John P. Delooper
Publications and Research
This article discusses mobile phone apps that can be used to scan photos and documents via the digital cameras built into smartphones. It talks about the history of these apps and what their best utility is in library settings. It also examines one specific project to digitize materials for a local history website.
We Are Each Other’S Breath: Tracing Interdependency Through Critical Poetic Inquiry, Karen Zaino, Jordan Bell
We Are Each Other’S Breath: Tracing Interdependency Through Critical Poetic Inquiry, Karen Zaino, Jordan Bell
Publications and Research
In this paper, we utilize poetic methods that seek to surface, but not overdetermine, the unanticipated relational excess produced through literacy practices. Karen, a queer white woman, and Jordan, a cis-gendered heterosexual Black man, wrote a series of letters to one another throughout the Spring 2020 semester. We turned to critical poetic inquiry to analyze the letters, interested in poetry’s capacity to highlight literacy’s critical power and its emergent potential. We found ourselves implicated in each other’s lives in new ways; we found our relationship both strengthened and tested. Such relational indeterminacy creates methodological challenges in literacy research. We found …
Resilience And Urban Regeneration Policies. Lessons From Community-Led Initiatives. The Case Study Of Canfugarolas In Mataro (Barcelona), Diego Saez Ujaque, Elisabet Roca, Rafael De Balanzó Joue, Pere Fuertes, Pilar Garcia-Almirall
Resilience And Urban Regeneration Policies. Lessons From Community-Led Initiatives. The Case Study Of Canfugarolas In Mataro (Barcelona), Diego Saez Ujaque, Elisabet Roca, Rafael De Balanzó Joue, Pere Fuertes, Pilar Garcia-Almirall
Publications and Research
This paper addresses socio-ecological, community-led resilience as the ability of the urban system to progress and adapt. This is based on the socio-cultural, self-organized case study of CanFugarolas in Mataró (Barcelona), for the recovery of a derelict industrial building and given the lack of attention to resilience emerging from grassroots. Facing rigidities (stagnation) observed under the provisions of urban regeneration policies (regulatory realm), evidenced in the proliferation of urban voids (infrastructural arena), the social subsystem stands as the enabler of urban progression. Under the heuristics of the Adaptive Cycle and Panarchy, the study embraces Fath’s model to analyze the transition …
Engaging Students About Race: Opportunities For Cross-Campus Partnerships During Black History Month, Mark Aaron Polger, Amy F. Stempler
Engaging Students About Race: Opportunities For Cross-Campus Partnerships During Black History Month, Mark Aaron Polger, Amy F. Stempler
Publications and Research
No abstract provided.
Psychosocial Factors Associated With Mask-Wearing Behavior During The Covid-19 Pandemic, Cliff (Yung-Chi) Chen, Mengjia Lei
Psychosocial Factors Associated With Mask-Wearing Behavior During The Covid-19 Pandemic, Cliff (Yung-Chi) Chen, Mengjia Lei
Publications and Research
Although increasing evidence has supported the efficacy of masks to prevent the spread of the coronavirus (COVID-19), inconsistent and noncompliant mask-wearing behavior has been observed among members of the society. Because mask-wearing is often considered a social contract, it is important to understand the psychosocial factors that influence people’s mask-wearing behavior in order to implement the necessary steps to respond to the pandemic. Based on the protection motivation theory (PMT), this study examined the cognitive factors (threat and coping appraisals) that contribute to mask-wearing behavior and the intention to engage in health protective behavior until the end of the pandemic. …
Graduate Student Employee Unionization In The Second Gilded Age, William A. Herbert, Joseph Van Der Naald
Graduate Student Employee Unionization In The Second Gilded Age, William A. Herbert, Joseph Van Der Naald
Publications and Research
In debates on the future of work, a common theme has been how work became
less secure through the denial of employee status. Though much of the attention
has focused on other industries, precarity has also affected those working in
higher education, including graduate student employees, contributing to what is
now called the “gig academy.” While universities have reassigned teaching and
research to graduate assistants, they have also refused to recognize them as
employees. Nevertheless, unionization has grown considerably since 2012, most
significantly at private institutions. Utilizing a unique dataset, this chapter
demonstrates that between 2012 and 2019, graduate student …
An Extensive Virtual Outreach Approach By Spe Dhaka University Chapter For Geoscience Education Amidst The Covid-19 Pandemic, Noshin Sharmili, Anika Nawar Mayeesha, Syed Humayun Akhter, Nazrul I. Khandaker
An Extensive Virtual Outreach Approach By Spe Dhaka University Chapter For Geoscience Education Amidst The Covid-19 Pandemic, Noshin Sharmili, Anika Nawar Mayeesha, Syed Humayun Akhter, Nazrul I. Khandaker
Publications and Research
The Society of Petroleum Engineers (SPE) Dhaka University (DU) Chapter in Bangladesh commenced its journey on 1st October 2007. From the beginning, it has always been students-centered and fixated to pique broader geoscience disciplined-based interests of the members and arrange several annual seminars, conferences, lecture programs, workshops, and general meetings. Many of these webinars were led by distinguished geoscience professionals known domestically and globally. Engaging and inspiring students, particularly females, in practical and innovative thinking concerning the present energy crisis and exploring the world’s energy sectors remain the central theme in its offerings. The SPE DU Chapter organized a wide …
Partisanship And The Politics Of Covid Vaccine Hesitancy, David Jones, Monika L. Mcdermott
Partisanship And The Politics Of Covid Vaccine Hesitancy, David Jones, Monika L. Mcdermott
Publications and Research
Has partisan polarization reached the stage that it now affects Americans’ decisions whether or not to get vaccinated against a pervasive and deadly virus such as COVID-19? To date, the evidence has largely been hypothetical—collected before the vaccine was widely available—superficial, or contradictory. Using two original surveys conducted at two different time periods after vaccines became available, this study represents one of the first efforts to systematically analyze the role of party affiliation in predicting vaccine hesitancy. We find that even after controlling for a host of demographic and attitudinal variables, Republicans are significantly less likely—and Democrats more likely—to be …
Ensuring Survey Research Data Integrity In The Era Of Internet Bots, Marybec Griffin, Richard J. Martino, Caleb Loschiavo, Camilla Comer-Carruthers, Kristen D. Krause, Christopher B. Stults, Perry N. Halkitis
Ensuring Survey Research Data Integrity In The Era Of Internet Bots, Marybec Griffin, Richard J. Martino, Caleb Loschiavo, Camilla Comer-Carruthers, Kristen D. Krause, Christopher B. Stults, Perry N. Halkitis
Publications and Research
We used an internet-based survey platform to conduct a cross-sectional survey regarding the impact of COVID-19 on the LGBTQ + population in the United States. While this method of data collection was quick and inexpensive, the data collected required extensive cleaning due to the infiltration of bots. Based on this experience, we provide recommendations for ensuring data integrity. Recruitment conducted between May 7 and 8, 2020 resulted in an initial sample of 1251 responses. The Qualtrics survey was disseminated via social media and professional association listservs. After noticing data discrepancies, research staff developed a rigorous data cleaning protocol. A second …
If You Build It, Will They Come? Reflections On Creating A Community College Library Makerspace, Lawren Wilkins, John P. Delooper
If You Build It, Will They Come? Reflections On Creating A Community College Library Makerspace, Lawren Wilkins, John P. Delooper
Publications and Research
This article describes one community college library’s experience creating and implementing a makerspace. It discusses the setup process, lessons learned, criticisms from patrons and staff, and more.
"Writing Unspeakable Things: Speechlessness, Abjection, And The Ethics/Aesthetics Of (Not) Representing Sexual Violence In Three Korean American "Comfort Women' Novels", M Laura Barberan Reinares
"Writing Unspeakable Things: Speechlessness, Abjection, And The Ethics/Aesthetics Of (Not) Representing Sexual Violence In Three Korean American "Comfort Women' Novels", M Laura Barberan Reinares
Publications and Research
This article analyzes “comfort women” novels by the Korean American authors Therese Park, Nora Okja Keller, and Chang-rae Lee in terms of the ethics and aesthetics of representing sexual violence through language. I specifically look at these authors’ stylistic strategies to describe rape in writing and how they (more or less successfully) avoid voyeuristic portrayals of the “comfort women” by controlling the narrative point of view and relying on traumatic “speechlessness” and abjection. Building on relevant notions from the fields of photography, cinematography, philosophy, and psychoanalysis, this analysis suggests that in-progress representations of rape in language become a futile project …
Addressing Structural Racism In The Health Workforce, Randl B. Dent, Anushree Vichare, Jaileessa Casimir
Addressing Structural Racism In The Health Workforce, Randl B. Dent, Anushree Vichare, Jaileessa Casimir
Publications and Research
One of the greatest challenges facing the United States are health inequities among racial/ethnic and other marginalized populations. The deep-rooted structural racism embedded in our social systems, including our health care system and health workforce, is a core cause of racial health inequities. 1 Among many definitions of institutionalized or structural racism, Dr Jones 2 best defines it as: “Differential access to goods, services and opportunities of society by race ... It is structural, having been codified in our institutions of custom, practice, and law, so there need not be an identifiable perpetrator.” Dr Jones further explains that to set …
Reports And Commands: Deciphering A Health Exhibition Using The Speaking Mnemonic, David H. Lee
Reports And Commands: Deciphering A Health Exhibition Using The Speaking Mnemonic, David H. Lee
Publications and Research
The Amazing You exhibition at the Tampa Museum of Science and Industry had over 400 different multimedia health exhibits. Visitors walked through life stages, from conception through death, the exhibits at first showcasing developmental milestones, then diseases and chronic conditions associated with ageing. Museum executives described the exhibition as a public health intervention that stressed disease prevention, screening and behaviour change. This piece considers the question: What makes an exhibition be a health intervention? To describe complexities of the communication environment I use a mnemonic device called SPEAKING, an acronym for ‘Scene/Setting, Participants, Ends, Act Sequence, Key, Instrumentalites, Norms and …
“Los Programadores Debieron Pensarse Como Dos Veces”: Exploring The Intersections Of Language, Power And Technology With Bi/Multilingual Students, Sara Vogel
Publications and Research
Critical computing approaches to K-12 Computer Science (CS) education aim to promote justice in computing and the wider world. Despite being intertwined with inequitable power dynamics in computing, issues of linguistic (in)justice have received less attention in critical computing. In this article, I draw on theoretical ideas from sociolinguistics and critical computing to analyze qualitative data collected in computing and technology-integrated language and humanities classes serving emergent bi/multilingual middle school students. Conversations about language, technology, and power were close at hand in focal classrooms, and surfaced in moments when students acted as users and critics of, and tinkerers with digital …
Analog Video In The Age Of Digital Data: A Case Study Of Shigeko Kubota's "Social Practice", Helena Shaskevich, Lia Robinson
Analog Video In The Age Of Digital Data: A Case Study Of Shigeko Kubota's "Social Practice", Helena Shaskevich, Lia Robinson
Publications and Research
If Nam June Paik truly is the “father of video art,” as so many scholars claim, then Shigeko Kubota is in many ways its mother, performing the unacknowledged and undervalued labor of managing the “house” of video and taking care of its inhabitants. My digital art history project for Panorama, which performs a data-driven deep dive into Kubota’s networks, argues that Kubota’s legacy must be understood as a lived, “social practice” of care for video art and its communities.
Intergenerational Differences In Dietary Acculturation Among Ghanaian Immigrants Living In New York City: A Qualitative Study, Margrethe F. Horlyck-Romanovsky, Terry T.-K Huang, Ramatu Ahmed, Sandra E. Echeverria, Katarzyna Wyka, May May Leung, Anne E. Sumner, Melissa Fuster
Intergenerational Differences In Dietary Acculturation Among Ghanaian Immigrants Living In New York City: A Qualitative Study, Margrethe F. Horlyck-Romanovsky, Terry T.-K Huang, Ramatu Ahmed, Sandra E. Echeverria, Katarzyna Wyka, May May Leung, Anne E. Sumner, Melissa Fuster
Publications and Research
Dietary acculturation may explain the increasing risk of diet-related diseases among African immigrants in the United States (US). We interviewed twenty-five Ghanaian immigrants (Youth n 13, Age (Mean ± SD) 20 y±5⋅4, Parents (n 6) and Grandparents (n 6) age 58⋅7± 9⋅7) living in New York City (NYC) to (a) understand how cultural practices and the acculturation experience influence dietary patterns of Ghanaian immigrants and (b) identify intergenerational differences in dietary acculturation among Ghanaian youth, parents and grandparents. Dietary acculturation began in Ghana, continued in NYC and was perceived as a positive process. At the interpersonal level, parents encouraged youth …
Police Officers’ Best Friend?: An Exploratory Analysis Of The Effect Of Service Dogs On Perceived Organizational Support In Policing, Kenneth M. Quick, Eric L. Piza
Police Officers’ Best Friend?: An Exploratory Analysis Of The Effect Of Service Dogs On Perceived Organizational Support In Policing, Kenneth M. Quick, Eric L. Piza
Publications and Research
This study explored the effectiveness of a novel technique for police departments to support their officers and promote wellness: the use of service dogs. We evaluated officer perceptions in two mid-sized, municipal police departments that have wellness programs with a service dog that is permanently assigned to a full-time police officer handler: Groton and Naugatuck, Connecticut. We assessed 6 factors believed to influence police officer wellness including: operational and organizational stress using the Police Stress Questionnaire (McCreary & Thompson, 2006); topical stressors including those related to the COVID-19 pandemic, police use of force and community relations, and police reform efforts; …
Aurora Kinase A Inhibition Reverses The Warburg Effect And Elicits Unique Metabolic Vulnerabilities In Glioblastoma, Trang T. T. Nguyen, Enyuan Shang, Chang Shu, Sungsoo Kim, Angeliki Mela, Nelson Humala, Aayushi Mahajan, Hee Won Yang, Hasan Orhan Akman, Catarina M. Quinzii, Guoan Zhang, Mike-Andrew Westhoff, Georg Karpel-Massler, Jeffrey N. Bruce, Peter Canoll, Markus D. Siegelin
Aurora Kinase A Inhibition Reverses The Warburg Effect And Elicits Unique Metabolic Vulnerabilities In Glioblastoma, Trang T. T. Nguyen, Enyuan Shang, Chang Shu, Sungsoo Kim, Angeliki Mela, Nelson Humala, Aayushi Mahajan, Hee Won Yang, Hasan Orhan Akman, Catarina M. Quinzii, Guoan Zhang, Mike-Andrew Westhoff, Georg Karpel-Massler, Jeffrey N. Bruce, Peter Canoll, Markus D. Siegelin
Publications and Research
Aurora kinase A (AURKA) has emerged as a drug target for glioblastoma (GBM). However, resistance to therapy remains a critical issue. By integration of transcriptome, chromatin immunoprecipitation sequencing (CHIP-seq), Assay for Transposase-Accessible Chromatin sequencing (ATAC-seq), proteomic and metabolite screening followed by carbon tracing and extracellular flux analyses we show that genetic and pharmacological AURKA inhibition elicits metabolic reprogramming mediated by inhibition of MYC targets and concomitant activation of Peroxisome Proliferator Activated Receptor Alpha (PPARA) signaling. While glycolysis is suppressed by AURKA inhibition, we note an increase in the oxygen consumption rate fueled by enhanced fatty acid oxidation (FAO), which was …
Our Year Of Remote Reference: Covid19’S Impact On Reference Services And Librarians, Sarah B. Cohn, Rebecca Hyams
Our Year Of Remote Reference: Covid19’S Impact On Reference Services And Librarians, Sarah B. Cohn, Rebecca Hyams
Publications and Research
After a full year of providing fully remote library reference due to the COVID-19 pandemic campus closures, this exploratory study looks at reference practices of libraries, and librarian response to those practices, at a large, urban, public university. This article focuses on the impact COVID-19 had on reference services themselves, as well as the perceptions of those who provide them.
Psilocybin Newspaper Coverage – Sentiment And Frequency (1989-2020), Dax Oliver
Psilocybin Newspaper Coverage – Sentiment And Frequency (1989-2020), Dax Oliver
Publications and Research
A growing body of medical research has focused on the chemical compound psilocybin in recent years. However, this research is not merely a scientific issue but also a social and political one. In the 1960s, psilocybin and other psychedelics were often ingested outside of research settings. This alarmed many people, resulting in severe legal restrictions on psilocybin research. Today, many psilocybin advocates hope that it will avoid the negative public sentiment of the 1960s. To help gauge public sentiment about other psychoactive compounds, some studies have examined newspaper coverage. The present study hoped to build a similar gauge with newspaper …
Advancing Gender Equity Through Legislation: Overview Of Select Laws Passed From 2014–2020, Maria J. D’Agostino, Nicole M. Elias
Advancing Gender Equity Through Legislation: Overview Of Select Laws Passed From 2014–2020, Maria J. D’Agostino, Nicole M. Elias
Publications and Research
Advancing Gender Equity through Legislation: A Compilation of Laws Passed from 2014 - 2020 aims to provide New York City residents with information about legislation passed under the de Blasio administration that aims to promote gender equity in the city.
Safety And Belonging In Immigrant-Serving Districts: Domains Of Educator Practice In A Charged Political Landscape, Rebecca Lowenhaupt, Dafney Blanca Dabach, Ariana Mangual Figueroa
Safety And Belonging In Immigrant-Serving Districts: Domains Of Educator Practice In A Charged Political Landscape, Rebecca Lowenhaupt, Dafney Blanca Dabach, Ariana Mangual Figueroa
Publications and Research
Drawing from a context of reception framework, this article asks the following questions: How do educators describe issues of safety and belonging in the context of a charged immigration policy climate? What practices have educators developed to support immigrant-origin youth? And, what are the relationships between educators’ perceptions of safety and belonging and educator practices? We analyze educators’ survey responses administered across six school districts in different contexts across the United States, including the Northeast, Midwest, South, and West. We synthesize four domains of educator practice: signaling affirmation, building shared knowledge and capacity, finding and mobilizing resources, and creating space …
Teaching Machine Learning For The Physical Sciences: A Summary Of Lessons Learned And Challenges, Viviana Acquaviva
Teaching Machine Learning For The Physical Sciences: A Summary Of Lessons Learned And Challenges, Viviana Acquaviva
Publications and Research
This paper summarizes some challenges encountered and best practices established in several years of teaching Machine Learning for the Physical Sciences at the undergraduate and graduate level. I discuss motivations for teaching ML to physicists, desirable properties of pedagogical materials, such as accessibility, relevance, and likeness to real-world research problems, and give examples of components of teaching units.
An Adaptive Cryptosystem On A Finite Field, Awnon Bhowmik, Unnikrishnan Menon
An Adaptive Cryptosystem On A Finite Field, Awnon Bhowmik, Unnikrishnan Menon
Publications and Research
Owing to mathematical theory and computational power evolution, modern cryptosystems demand ingenious trapdoor functions as their foundation to extend the gap between an enthusiastic interceptor and sensitive information. This paper introduces an adaptive block encryption scheme. This system is based on product, exponent, and modulo operation on a finite field. At the heart of this algorithm lies an innovative and robust trapdoor function that operates in the Galois Field and is responsible for the superior speed and security offered by it. Prime number theorem plays a fundamental role in this system, to keep unwelcome adversaries at bay. This is a …
Threshold Concentration And Random Collision Determine The Growth Of The Huntingtin Inclusion From A Stable Core, Sen Pei, Theresa C. Swayne, Jeffrey F. Morris, Lesley Emtage
Threshold Concentration And Random Collision Determine The Growth Of The Huntingtin Inclusion From A Stable Core, Sen Pei, Theresa C. Swayne, Jeffrey F. Morris, Lesley Emtage
Publications and Research
The processes underlying formation and growth of unfolded protein inclusions are relevant to neurodegenerative diseases but poorly characterized in living cells. In S. cerevisiae, inclusions formed by mutant huntingtin (mHtt) have some characteristics of biomolecular condensates but the physical nature and growth mechanisms of inclusion bodies remain unclear. We have probed the relationship between concentration and inclusion growth in vivo and find that growth of mHtt inclusions in living cells is triggered at a cytoplasmic threshold concentration, while reduction in cytoplasmic mHtt causes inclusions to shrink. The growth rate is consistent with incorporation of new material through collision and coalescence. …
"Introduction" The Social Movement Archive, Nora Almeida, Jen Hoyer
"Introduction" The Social Movement Archive, Nora Almeida, Jen Hoyer
Publications and Research
The Social Movement Archive examines the role of cultural production within social justice struggles and within archives. This book contains reproductions of political ephemera—zines, banners, stickers, posters, memes, and more—alongside 15 interviews with artists and activists who have worked across a broad range of movements including: women’s liberation, disability rights, housing justice, Black liberation, anti-war, Indigenous sovereignty, immigrant rights, and prisoner abolition, among others. These images and accompanying conversations illustrate the power of political art and ephemera to transform cultural practices, places, and communities; and its capacity to be a force for disruption in archival spaces.