Digital Commons Network^™

Cuny Librarians In Cuba, William Blick

Publications and Research

On January 15, a team of bold, innovative librarians from the City University of New York (CUNY) set out to do what many librarians in the United States have not: travel to Cuba for a weeklong expedition of cultural, professional, and informational exchange. The mission was as exhilarating as it was challenging. I was among the ten librarians in the delegation representing a wide range of backgrounds and skills. Most of us did not know one another previously, and the potluck of talent was a unique aspect of the trip. Throughout the journey, members demonstrated a spirit of adventure and …

Testing The Efficacy Of Mypsychlab To Replace Traditional Instruction In A Hybrid Course, Kasey L. Powers, Patricia J. Brooks, Magdalena Galazyn, Seamus Donnelly

Publications and Research

Online course-packs are marketed as improving grades in introductory-level coursework, yet it is unknown whether these course-packs can effectively replace, as opposed to supplement, in-class instruction. This study compared learning outcomes for Introductory Psychology students in hybrid and traditional sections, with hybrid sections replacing 30% of in-class time with online homework using the MyPsychLab course-pack and Blackboard course management system. Data collected over two semesters (N = 730 students in six hybrid and nine traditional sections of ∼50 students) indicated equivalent final-grade averages and rates of class attrition. Although exam averages did not differ by class format, exam grades in …

Controlled Microfluidics To Examine Growth-Factor Induced Migration Of Neural Progenitors In The Drosophila Visual System, Cade Beck, Tanya Singh, Angela Farooqi, Tadmiri Venkatesh, Maribel Vazquez

Publications and Research

BACKGROUND:

The developing visual system in Drosophila melanogaster provides an excellent model with which to examine the effects of changing microenvironments on neural cell migration via microfluidics, because the combined experimental system enables direct genetic manipulation, in vivo observation, and in vitro imaging of cells, post-embryo. Exogenous signaling from ligands such as fibroblast growth factor (FGF) is well-known to control glia differentiation, cell migration, and axonal wrapping central to vision.

NEW METHOD:

The current study employs a microfluidic device to examine how controlled concentration gradient fields of FGF are able to regulate the migration of vision-critical glia cells with and …

Awareness Of Rabies And Response To Dog Bites In A Bangladesh Community, Sumon Ghosh, Sukanta Chowdhury, Najmul Haider, Rajub K. Bhowmik, Md. S. Rana, Aung S. Prue Marma, Muhammad B. Hossain, Nitish C. Debnath, Be-Nazir Ahmed

Publications and Research

Community awareness regarding rabies and treatment seeking behaviours are critical both for the prevention and control of the disease in human and animals. We conducted a study to explore people’s awareness about rabies, their attitudes towards dogs and practices associated with treating dog bites in Satkhira Sadar, a southwestern sub-district of Bangladesh. Of the total 3200 households (HHs) surveyed, the majority of the respondents have heard about rabies (73%) and there was a high level of awareness that dog bite is the main cause of rabies (86%), and that rabies can be prevented by vaccination (85%). However, 59% of the …

Attention Strongly Modulates Reliability Of Neural Responses To Naturalistic Narrative Stimuli, Jason J. Ki, Simon P. Kelly, Lucas C. Parra

Publications and Research

Attentional engagement is a major determinant of how effectively we gather information through our senses. Alongside the sheer growth in the amount and variety of information content that we are presented with through modern media, there is increased variability in the degree to which we “absorb” that information. Traditional research on attention has illuminated the basic principles of sensory selection to isolated features or locations, but it provides little insight into the neural underpinnings of our attentional engagement with modern naturalistic content. Here, we show inhumansubjects that the reliability of an individual’s neural responses with respect to a larger group …

Craigslist As A Source For Illicit Drugs: A Case Report And Review Of The Literature, Babak Tofighi, Alisha Desai, Christian Grov, Joshua D. Lee

Publications and Research

Introduction: Online drug markets and social media are facilitating the spread of information and sale of illicit substances. Online sites, such as Craigslist and Bluelight, underscore an emerging shift in contemporary drug consumerism.

Case Descriptions: We report on two cases. Case 1 is a 42-year-old male with a history of heroin-use disorder, presented for an initial visit to an office-based buprenorphine program, and reported having acquired heroin from Craigslist. Despite several harrowing experiences, Craigslist remained Patient 1’s primary method of purchasing heroin during a 14-month period. Craigslist ads also redirected the patient to the web site Bluelight, which …

Transformation From Text To Voicethreads And Not Looking Back, Curtis Izen

Publications and Research

No abstract provided.

Parasitic Diseases Of The Central Nervous System: Lessons For Clinicians And Policy Makers, Arturo Carpio, Matthew L. Romo, R.M.E. Parkhouse, Brooke Short, Tarun Dua

Publications and Research

Parasitic diseases of the central nervous system are associated with high mortality and morbidity, especially in resource-limited settings. The burden of these diseases is amplified as survivors are often left with neurologic sequelae affecting mobility, sensory organs, and cognitive functions, as well as seizures/epilepsy. These diseases inflict suffering by causing lifelong disabilities, reducing economic productivity, and causing social stigma. The complexity of parasitic life cycles and geographic specificities, as well as overlapping clinical manifestations in the host reflecting the diverse pathogenesis of parasites, can present diagnostic challenges. We herein provide an overview of these parasitic diseases and summarize clinical aspects, …

Experimental Demonstration Of Topological Effects In Bianisotropic Metamaterials, Alexey P. Slobozhanyuk, Alexander B. Khanikaev, Dmitry S. Filonov, Daria A. Smirnova, Andrey E. Miroshnichenko, Yuri S. Kivshar

Publications and Research

Existence of robust edge states at interfaces of topologically dissimilar systems is one of the most fascinating manifestations of a novel nontrivial state of matter, a topological insulator. Such nontrivial states were originally predicted and discovered in condensed matter physics, but they find their counterparts in other fields of physics, including the physics of classical waves and electromagnetism. Here, we present the first experimental realization of a topological insulator for electromagnetic waves based on engineered bianisotropic metamaterials. By employing the near-field scanning technique, we demonstrate experimentally the topologically robust propagation of electromagnetic waves around sharp corners without backscattering effects.

Predicted Molecular Signaling Guiding Photoreceptor Cell Migration Following Transplantation Into Damaged Retina, Uchenna John Unachukwu, Alice Warren, Ze Li, Shawn Mishra, Jing Zhou, Moira Sauane, Hyungsik Lim, Maribel Vazquez, Stephen Redenti

Publications and Research

To replace photoreceptors lost to disease or trauma and restore vision, laboratories around the world are investigating photoreceptor replacement strategies using subretinal transplantation of photoreceptor precursor cells (PPCs) and retinal progenitor cells (RPCs). Significant obstacles to advancement of photoreceptor cell-replacement include low migration rates of transplanted cells into host retina and an absence of data describing chemotactic signaling guiding migration of transplanted cells in the damaged retinal microenvironment. To elucidate chemotactic signaling guiding transplanted cell migration, bioinformatics modeling of PPC transplantation into light-damaged retina was performed. The bioinformatics modeling analyzed whole-genome expression data and matched PPC chemotactic cell-surface receptors to …

Dengue-Induced Autophagy, Virus Replication And Protection From Cell Death Require Er Stress (Perk) Pathway Activation, E. Datan, S. G. Roy, G. Germain, N. Zali, J. E. Mclean, G. Golshan, S. Harbajan, R. A. Lockshin, Z. Zakeri

Publications and Research

Avirus that reproduces in a host without killing cells can easily establish a successful infection. Previously, we showed that dengue-2, a virus that threatens 40% of the world, induces autophagy, enabling dengue to reproduce in cells without triggering cell death. Autophagy further protects the virus-laden cells from further insults. In this study, we evaluate how it does so; we show that dengue upregulates host pathways that increase autophagy, namely endoplasmic reticulum (ER) stress and ataxia telangiectasiamutated (ATM) signaling followed by production of reactive oxygen species (ROS). Inhibition of ER stress or ATM signaling abrogates the dengueconferred protection against other cell …

Characterization And Recombinant Expression Of Terebrid Venom Peptide From Terebra Guttata, John Moon, Juliette Gorson, Mary Elizabeth Wright, Laurel Yee, Samer Khawaja, Hye Young Shin, Yasmine Karma, Rajeeva Lochan Musunri, Michelle Yun, Mandë Holford

Publications and Research

Venom peptides found in terebrid snails expand the toolbox of active compounds that can be applied to investigate cellular physiology and can be further developed as future therapeutics. However, unlike other predatory organisms, such as snakes, terebrids produce very small quantities of venom, making it difficult to obtain sufficient amounts for biochemical characterization. Here, we describe the first recombinant expression and characterization of terebrid peptide, teretoxin Tgu6.1, from Terebra guttata. Tgu6.1 is a novel forty-four amino acid teretoxin peptide with a VI/VII cysteine framework (C–C–CC–C–C) similar to O, M and I conotoxin superfamilies. A ligation-independent cloning strategy with an ompT …

Age And Employee Green Behaviors: A Meta-Analysis, Brenton M. Wiernik, Stephan Dilchert, Deniz S. Ones

Publications and Research

Recent economic and societal developments have led to an increasing emphasis on organizational environmental performance. At the same time, demographic trends are resulting in increasingly aging labor forces in many industrialized nations. Commonly held stereotypes suggest that older workers are less likely to be environmentally responsible than younger workers. To evaluate the degree to which such age differences are present, we meta-analyzed 132 independent correlations and 336 d-values based on 4676 professional workers from 22 samples in 11 countries. Contrary to popular stereotypes, age showed small positive relationships with pro-environmental behaviors, suggesting that older adults engaged in these workplace …

Age And Employee Green Behaviors: A Meta-Analysis, Brenton M. Wiernik, Stephan Dilchert, Deniz S. Ones

Publications and Research

Recent economic and societal developments have led to an increasing emphasis on organizational environmental performance. At the same time, demographic trends are resulting in increasingly aging labor forces in many industrialized nations. Commonly held stereotypes suggest that older workers are less likely to be environmentally responsible than younger workers. To evaluate the degree to which such age differences are present, we meta-analyzed 132 independent correlations and 336 d-values based on 4676 professional workers from 22 samples in 11 countries. Contrary to popular stereotypes, age showed small positive relationships with pro-environmental behaviors, suggesting that older adults engaged in these workplace …

Genesis And Growth Of Extracellular Vesicle-Derived Microcalcification In Atherosclerotic Plaques, Joshua D. Hutcheson, Claudia Goettsch, Sergio Bertazzo, Natalia Maldonado, Jessica L. Ruiz, Wilson Goh, Katsumi Yabusaki, Tyler Faits, Carlijn Bouten, Gregory Franck, Thibaut Quillard, Peter Libby, Masanori Aikawa, Sheldon Weinbaum, Elena Aikawa

Publications and Research

Clinical evidence links arterial calcification and cardiovascular risk. Finite-element modelling of the stress distribution within atherosclerotic plaques has suggested that subcellular microcalcifications in the fibrous cap may promote material failure of the plaque, but that large calcifications can stabilize it. Yet the physicochemical mechanisms underlying such mineral formation and growth in atheromata remain unknown. Here, by using three-dimensional collagen hydrogels that mimic structural features of the atherosclerotic fibrous cap, and high-resolution microscopic and spectroscopic analyses of both the hydrogels and of calcified human plaques, we demonstrate that calcific mineral formation and maturation results from a series of events involving the …

Improving Landslide Hazard And Risk Mapping In Guatemala Using Terrain Aspect, Yuri Gorohkovich, Elia Axinia Machado, Luis Ivan Giron Melgar, Mahta Ghahremani

Publications and Research

Guatemala is in the path of numerous atmospheric hazards that trigger landslides by saturating mountain slopes with water reducing their safety factor. Available local studies of landslide characterization in Guatemala have indicated the importance of slope in hazard and risk mapping, but, for the most part, ignored another topographic index: aspect. However, many regional studies analyzing the effect of hurricanes on terrain show that Caribbean and Central American locations experience higher impact from hurricanes and storms on eastern, southeastern, southern and southwestern slopes. Since hazard and risk mapping focuses on infrastructure and settlements located on slopes with various orientations, this …

Engineered Protein Polymer-Gold Nanoparticle Hybrid Materials For Small Molecule Delivery, Min Dai, Ja Frezzo, E Sharma, R Chen, N Singh, C Yuvienco, E Caglar, S Xiao, A Saxena, Jk Montclare

Publications and Research

We have fabricated protein polymer-gold nanoparticle (P-GNP) nanocomposites that exhibit enhanced binding and delivery properties of the small hydrophobic molecule drug, curcumin, to the model breast cancer cell line, MCF-7. These hybrid biomaterials are constructed via in situ GNP templated-synthesis with genetically engineered histidine tags. The P-GNP nanocomposites exhibit enhanced small molecule loading, sustained release and increased uptake by MCF-7 cells. When compared to the proteins polymers alone, the P-GNPs demonstrate a greater than 7-fold increase in curcumin binding, a nearly 50% slower release profile and more than 2-fold increase in cellular uptake of curcumin. These results suggest that P-GNP …

Chiropractors’ Perception Of Occupational Stress And Its Influencing Factors: A Qualitative Study Using Responses To Open-Ended Questions, Shawn Williams

Publications and Research

Background: Job stress and emotional exhaustion have been shown to have a negative impact on the helping professional. The development and causal relations of job stress and emotional exhaustion are rather unclear in the chiropractic profession. The objective of this study is to understand the main sources of occupational stress and emotional exhaustion among doctors of chiropractic.

Methods: Analysis of the written responses to web-based open-ended questionnaire was performed using an interpretive research methodology. Additionally, cross tabulation and Chi square statistical tests were conducted to match and couple the demographic data with the categorical themes.

Results: Fourteen professional stress categories …

Layer-Switching Cost And Optimality In Information Spreading On Multiplex Networks, Byungjoon Min, Sang-Hwan Gwak, Nanoom Lee, K. I. Goh

Publications and Research

We study a model of information spreading on multiplex networks, in which agents interact through multiple interaction channels (layers), say online vs. offline communication layers, subject to layerswitching cost for transmissions across different interaction layers. The model is characterized by the layer-wise path-dependent transmissibility over a contact, that is dynamically determined dependently on both incoming and outgoing transmission layers. We formulate an analytical framework to deal with such path-dependent transmissibility and demonstrate the nontrivial interplay between the multiplexity and spreading dynamics, including optimality. It is shown that the epidemic threshold and prevalence respond to the layer-switching cost non-monotonically and that …

Sexual Behavior Varies Between Same-Race And Different-Race Partnerships: A Daily Diary Study Of Highly Sexually Active Black, Latino, And White Gay And Bisexual Men, Christian Grov, Demetria Cain, H. Jonathan Rendina, Ana Ventuneac, Jeffrey T. Parsons

Publications and Research

Background. Gay and bisexual men (GBM) are at elevated risk for gonorrhea and chlamydia trachomatis (GC/CT). Rectal GC/CT symptoms may be less obvious than urethral, increasing opportunities for undiagnosed rectal GC/CT.

Method. A U.S. national sample of 1,071 GBM completed urethral and rectal GC/CT testing and an online survey.

Results. In total, 6.2% were GC/CT positive (5.3% rectal, 1.7% urethral). We calculated adjusted (for education, race, age, relationship status, having health insurance, and income) odds ratios for factors associated with rectal and urethral GC/CT diagnoses. Age was inversely associated with urethral and rectal GC/CT. Compared to White men, Latinos had …

I Don't Want You To Work As Me, I Want You To Work For Me, Emma Hedditch

Publications and Research

Performance, video scripts, and other writings, 2008 - 2015. This self-published ebook collects together performance and video scripts made by artist Emma Hedditch. These scripts take a poetic and informative form. They were performed at Flat-time House, London, Kunsthaus, Bregenz, Musee de Montmatre, Paris amongst other venues between 2008 and 2015.

100 Years Ago: Wilson Loses Another Cabinet Member, Keith J. Muchowski

Publications and Research

This invited blog post explores the circumstances under Lindley M. Garrison resigned as President Woodrow Wilson's Secretary of War in February 1916.

Spectators Or Patriots? Citizens In The Information Age, Amrita Dhawan

Publications and Research

In theory, a strong democracy rests on robust citizen participation. The practice in most democracies is quite different. This gap presents a challenge, which can be narrowed by augmenting civic education to bring it up to date with the current information environment and thus give citizens the opportunity to participate. Robert Dahl’s work on democracy provides a model that looks at this problem structurally. He writes about the ideals and the actual institutions necessary for a democracy and if we situate his model in the modern information environment we get a better idea of how to improve civic education. Successful …

Love, Sex, Disability, Coming Out And John Travolta In New York And Jerusalem: A Twenty-Year Journey, Scott Sheidlower

Publications and Research

No abstract provided.

Exploring The Use Of An Iphone App: A Novel Approach To Dietary Assessment, Melissa Keeney, Ming-Chin Yeh, Rissa Landman, May May Leung, Ann Gaba, Khursheed Navder

Publications and Research

Recent advancements in smartphone technology have provided new methods of dietary assessment. An iTunes application (app) called Meal Snap lets users take pictures of the meal they eat, and then estimates the calories of the food items eaten. We conducted a pilot study to explore the user-friendliness and calorie estimation functions of the Meal Snap app. Two female nutrition graduate students pilot-tested the Meal Snap app. Using the app, each student took pictures of foods and drinks consumed daily for two weeks. The data were analyzed using the Nutritionist ProTM software, version 4.4.0. The mean daily caloric intake obtained from …

Neighborhood Matters: The Impact Of Hispanic Ethnic Density On Future Depressive Symptoms 1-Year Following An Acs Event Among Hispanic Patients, Ellen-Ge Denton, Jonathan Shaffer, Carmela Alcantara, Esteban Cadermil

Publications and Research

The Ethnic Density hypothesis posits that living around others from similar ethnic backgrounds reduces the risk of adverse mental health outcomes such as depression. Contrary to this hypothesis, previous work has shown that Hispanic ethnic density is cross-sectionally associated with increased depressive symptom severity among patients hospitalized with an acute coronary syndrome (ACS; myocardial infarction or unstable angina pectoris). To date, no study has examined the prospective association of Hispanic ethnic density on long-term depressive symptom severity following an acute medical event. We prospectively assessed the impact of Hispanic ethnic density on depressive symptoms, 1-year following an ACS event, among …

Losing It: The Construction And Stigmatization Of Obesity On Reality Television In The United States, Alisa Roost

Publications and Research

No abstract provided.

Hydrodynamic Loading In Concomitance With Exogenous Cytokine Stimulation Modulates Differentiation Of Bovine Mesenchymal Stem Cells Towards Osteochondral Lineages, Stephen M. Goldman, Gilda A. Barabino

Publications and Research

Background: Mesenchymal stem cells (MSCs) are viewed as a having significant potential for tissue engineering and regenerative medicine therapies. Clinical implementation of MSCs, however, demands that their preparation be stable and reproducible. Given that environmental and bioprocessing parameters such as substrate stiffness, seeding densities, culture medium composition, and mechanical loading can result in undirected differentiation of the MSC population, the objective of this study was to systematically investigate how hydrodynamic loading influences the differentiation of bone marrow-derived mesenchymal stem cells (MSCs) towards the osteochondral lineages both in the presence and absence of exogenous, inductive factors.

Methods: Expanded bovine MSCs were …

Unmanned Arial Systems (Uas) In The Local Public Safety Environment: A Review, Hiram Taylor, Blount-Hill Blount-Hill, Charles R. Jennings

Publications and Research

No abstract provided.

Annotate The Web: Four Ways To Mark Up Web Content, Robin Camille Davis

Publications and Research

Web annotation has been a pipe dream almost since the birth of the Internet itself. Commenting in the margins of a text itself is so simple for paper and print, yet replicating the experience online remains elusive. In this article, I examine four tools for private or public web annotation. Hypothesis and Genius offer users a shareable way to annotate webpages line by line and start conversations in the margins. Pinboard and Evernote allow users to organize and save web documents and add private annotations.