Digital Commons Network^™

Bow-Tie Signaling In C-Di-Gmp: Machine Learning In A Simple Biochemical Network, Jinyuan Yan, Maxime Deforet, Kerry E. Boyle, Rayees Rahman, Raymond Liang, Chinweike Okegbe, Lars E. P. Dietrich, Weigang Qiu, Joao B. Xavier

Publications and Research

Bacteria of many species rely on a simple molecule, the intracellular secondary messenger c-di-GMP (Bis-(3'-5')-cyclic dimeric guanosine monophosphate), to make a vital choice: whether to stay in one place and form a biofilm, or to leave it in search of better conditions. The c-di-GMP network has a bow-tie shaped architecture that integrates many signals from the outside worldÐthe input stimuliÐinto intracellular c-di-GMP levels that then regulate genes for biofilm formation or for swarming motilityÐthe output phenotypes. How does the `uninformed' process of evolution produce a network with the right input/output association and enable bacteria to make the right choice? Inspired …

The Influence Of The Electrode Dimension On The Detection Sensitivity Of Electric Cell–Substrate Impedance Sensing (Ecis) And Its Mathematical Modeling, Xudong Zhang, William Wang, Anis Nurashikin Nordin, Fang Li, Sunghoon Jang, Ioana Voiculescu

Publications and Research

Detection sensitivity is a crucial criterion in the design and application of ECIS sensors. The influence of sensing electrode dimension on detection sensitivity is investigated in this paper. Eight types of ECIS sensors were fabricated, and their experimental results reveal that smaller-radius working electrodes generate more sensitive impedance shift to cell density change. Also, the smaller radius of working electrodes yield higher impedance values, which improves signal-to-noise ratio. In a range from 1.0 mm to 3.5 mm, the distance between the working and counter electrodes does not affect impedance measurements. However, the distance should be large enough to prevent the …

Blogs As Channels For Disseminating Health Technology Innovations, Ashish Joshi, Rinzin Wangmo, Chioma Amadi

Publications and Research

Objectives: The objective of this study was to describe the features of health informatics blogs on the Internet.

Methods: A search was conducted in August, 2016 using the search engine, Google, and key words: ‘mobile health blog,’ ‘telehealth/telemedicine blog,’ ‘Electronic Health Record blog,’ ‘personalized health record blog,’ ‘population health decision support system blog,’ and ‘public/population health dashboard blog.’ The first 24 blogs resulting from each key word search were recorded, generating 144 blogs. A total of 109 unique blogs resulted after removing duplicates and non-functional sites.

Results: Blogs with ‘.com’ extensions were most prevalent (72%, n = 79). More than …

Dress And Sex: A Review Of Empirical Research Involving Human Participants And Published In Refereed Journals, Sharron J. Lennon, Alyssa Dana Adomaitis, Jayoung Koo, Kim K. P. Johnson

Publications and Research

Our research purpose was to assess research addressing relationships between dress and sex. Our review was focused on a 25 years span (i.e., 1990–2015) and on empirical research utilizing human participants published in refereed journals. Three main areas of research emerged: (1) dress used as cue to sexual information, (2) dress and sexual violence, and (3) dress, sex, and objectification. Our analyses revealed parents do invest their young children with sex-typed dress however sometimes children demand to wear such dress. Some women intentionally use dress to communicate sexual information but inferences about women who wear sexy dress can be misinterpreted …

The Triumph Of The Lie: How Honesty And Morality Died In Right-Wing Politics, Aaron Barlow

Publications and Research

No abstract provided.

T-Dna-Genome Junctions Form Early After Infection And Are Influenced By The Chromatin State Of The Host Genome, Shay Shilo, Pooja Tripathi, Cathy Melamed Bessudo, Oren Tzfadia, Theodore R. Muth, Avraham A. Levy

Publications and Research

Agrobacterium tumefaciens mediated T-DNA integration is a common tool for plant genome manipulation. However, there is controversy regarding whether T-DNA integration is biased towards genes or randomly distributed throughout the genome. In order to address this question, we performed high-throughput mapping of T-DNA-genome junctions obtained in the absence of selection at several time points after infection. T-DNA-genome junctions were detected as early as 6 hours post-infection. T-DNA distribution was apparently uniform throughout the chromosomes, yet local biases toward AT-rich motifs and T-DNA border sequence micro-homology were detected. Analysis of the epigenetic landscape of previously isolated sites of T-DNA integration in …

Pixuna Virus Modifies Host Cell Cytoskeleton To Secure Infection, Pedro Ignacio Gil, Guillermo Albrieu-Llinás, Estela Cecilia Mlewski, Marina Monetti, Laura Fozzatti, Cecilia Cuffini, José Fernández-Romero, Patricia Kunda, María Gabriela Paglini

Publications and Research

Pixuna virus (PIXV) is an enzootic member of the Venezuelan Equine Encephalitis Virus complex and belongs to the New World cluster of alphaviruses. Herein we explore the role of the cellular cytoskeleton during PIXV replication. We first identified that PIXV undergoes an eclipse phase consisting of 4 h followed by 20 h of an exponential phase in Vero cells. The infected cells showed morphological changes due to structural modifications in actin microfilaments (MFs) and microtubules (MTs). Cytoskeletonbinding agents, that alter the architecture and dynamics of MFs and MTs, were used to study the role of cytoskeleton on PIXV replication. The …

Higher Ed Opinions Divided Along Party Lines., Aldemaro Romero Jr.

Publications and Research

Until recently, higher education commanded a good standing in public opinion polls. According to a 2013 Gallup-Lumina Foundation survey, 72 percent of people in the U.S. thought that to have a college degree was “very important,” and 25 percent thought it was “somewhat important.”

However, that good image has been eroding rapidly. According to the results of a 2016 survey funded by the Kresge Foundation, Americans are increasingly uncertain about the necessity of college for success in the workforce. When asked the question, "Do you think that a college education is necessary for a person to be suc- cessful in …

Behar Unites The Arts And Technology., Aldemaro Romero Jr.

Publications and Research

“I was always artistically inclined from the time I was small, and I think I was fortunate to have parents who were very supportive of me.” This is how Professor Katherine Behar begins her life story, but she doesn’t claim that her family had no doubts whatsoever. “What I enjoy is doing a lot of different things. This was one of things that my parents were most concerned about, how I was going to find a career where I would be able to do all of the different things that I like doing.”

She has fulfilled her life’s ambitions by …

Tumor Necrosis Factor Dynamically Regulates The Mrna Stabilome In Rheumatoid Arthritis Fibroblast-Like Synoviocytes, Konstantinos Loupasakis, David Kuo, Upneet K. Sokhi, Christopher Sohn, Bethany Syracuse, Eugenia G. Giannopoulou, Sung Ho Park, Hyelim Kang, Gunnar Rätsch, Lionel B. Ivashkiv, George D. Kalliolias

Publications and Research

During rheumatoid arthritis (RA), Tumor Necrosis Factor (TNF) activates fibroblast-like synoviocytes (FLS) inducing in a temporal order a constellation of genes, which perpetuate synovial inflammation. Although the molecular mechanisms regulating TNF-induced transcription are well characterized, little is known about the impact of mRNA stability on gene expression and the impact of TNF on decay rates of mRNA transcripts in FLS. To address these issues we performed RNA sequencing and genome-wide analysis of the mRNA stabilome in RA FLS. We found that TNF induces a biphasic gene expression program: initially, the inducible transcriptome consists primarily of unstable transcripts but progressively switches …

Engaging Narratives Evoke Similar Neural Activity And Lead To Similar Time Perception, Samantha S. Cohen, Simon Henin, Lucas C. Parra

Publications and Research

It is said that we lose track of time - that “time flies” - when we are engrossed in a story. How does engagement with the story cause this distorted perception of time, and what are its neural correlates? People commit both time and attentional resources to an engaging stimulus. For narrative videos, attentional engagement can be represented as the level of similarity between the electroencephalographic responses of different viewers. Here we show that this measure of neural engagement predicted the duration of time that viewers were willing to commit to narrative videos. Contrary to popular wisdom, engagement did not …

African Film Distribution In The United States: Assessment And Prospective Analysis, Boukary Sawadogo

Publications and Research

No abstract provided.

Playing God: The Bible On The Broadway Stage By Henry Bial (Review), Christopher B. Swift

Publications and Research

No abstract provided.

Equality Archive: Open Educational Resources As Feminist Praxis, Shelly J. Eversley, Laurie Hurson

Publications and Research

Statement on EqualityArchive.com as an instance of open educational resources as feminist praxis.

Caries Classification, Diana V. Macri, Annie Chitlall

Publications and Research

It has been 10 years since Featherstone and colleagues presented their evidence-based model of caries management: caries management by risk assessment (CAMBRA). This approach relies on a careful analysis of a patients’ risk factors and protective factors. International and national organizations have long recognized the need for a new caries classification system that incorporates evidence-based approaches to halt progression of caries lesions and minimize the need for surgical intervention. Thus, the International Caries Detection and Assessment System (ICDAS) and the American Dental Association Caries Classification System (ADA CCS) were created. The purpose of this article is to briefly review the …

Remotivating The Black Vote: The Effect Of Low-Quality Information On Black Voters In The 2016 Presidential Election And How Librarians Can Intervene, Andrew P. Jackson, Denyvetta Davis, James Kelly Alston

Publications and Research

In a phenomenon that was surprising to many, given the racially charged nature of the 2016 presidential election, black voter turnout was significantly lower than the previous two elections. Donald Trump’s victory is attributable to many factors, one of which was the lower participation of black voters in several swing states. To a lesser extent, black support for third-party candidates also aided Trump’s victory. The lower black turnout itself is attributable to several factors, but one factor specifically in the LIS realm was the prevalence of low-quality information and rhetoric and a susceptibility that some black voters had to this …

On Variety: The Avant-Garde Between Pornography And Narrative, Kevin L. Ferguson

Publications and Research

This article analyzes Bette Gordon’s first feature film Variety (1983), reassessing how experimental novelist Kathy Acker’s contributions to the screenplay awkwardly positioned the film within contemporary cultural debates over pornography and the future of avant-garde filmmaking. While centered on an erotic thriller narrative concerning a woman’s entrée into the scuzzy world of New York City porno theaters, Gordon and Acker also take up in the film a series of three related representational problems for the 1980s: feminist approaches to pornography, narrative in an avant-garde tradition, and the role of speech and writing in film.

Contextualizing Developmental Math Content Into Introduction To Sociology In Community Colleges, Stuart Parker, Amy E. Traver, Jonathan Cornick

Publications and Research

Across community colleges in the United States, most students place into a developmental math course that they never pass. This can leave them without the math skills necessary to make informed decisions in major areas of social life and the college credential required for participation in growing sectors of our economy. One strategy for improving community college students’ pass rate in developmental math courses is the contextualization of developmental math content into the fabric of other courses. This article reviews an effort to contextualize developmental math content (i.e., elementary algebra) into Introduction to Sociology at Kingsborough Community College and Queensborough …

Brooks Studies How Asians Have Been Viewed By Americans, Aldemaro Romero Jr.

Publications and Research

“I went to a high school in northern California, up in the foothills near where gold was discovered in a little town called Auburn, and one thing I remember is that we didn’t really have any kind of world history.” Those are the first memories of the historian Charlotte Brooks about her profession.

Further, when it comes to her area of specialization—the history of Asians in America—her beginnings are even more modest. “Growing up in the gold rush country, I saw the old Chinese immigrant markers on the land and on the buildings everywhere. I knew my town had been …

Mixed Methods Not Mixed Messages: Improving Libguides With Student Usability Data, Nora Almeida, Junior R. Tidal

Publications and Research

This presentation describes a project to improve LibGuides version 2 research guides at the City Tech Library and to understand student design and learning modality preferences. It includes findings from a mixed methods usability study and illustrates how this data translates into executable design principles.

‘Speaking Truth’ Protects Underrepresented Minorities’ Intellectual Performance And Safety In Stem, Avi Ben-Zeev, Yula Paluy, Katlyn L. Milless, Emily J. Goldstein, Lyndsey Wallace, Leticia Márquez-Magaña, Kirsten Bibbins-Domingo, Mica Estrada

Publications and Research

We offer and test a brief psychosocial intervention, Speaking Truth to EmPower (STEP), designed to protect underrepresented minorities’ (URMs) intellectual performance and safety in science, technology, engineering, and math (STEM). STEP takes a ‘knowledge as power’ approach by: (a) providing a tutorial on stereotype threat (i.e., a social contextual phenomenon, implicated in underperformance and early exit) and (b) encouraging URMs to use lived experiences for generating be-prepared coping strategies. Participants were 670 STEM undergraduates [URMs (Black/African American and Latina/o) and non-URMs (White/European American and Asian/Asian American)]. STEP protected URMs’ abstract reasoning and class grades (adjusted for grade point average [GPA]) …

International Society Of Sports Nutrition Position Stand: Diets And Body Composition, Alan A. Aragon, Brad J. Schoenfeld, Robert Wildman, Susan Kleiner, Trisha Vandusseldorp, Lem Taylor, Conrad P. Earnest, Paul J. Arciero, Colin Wilborn, Douglas S. Kalman, Jeffrey R. Stout, Darryn S. Willoughby, Bill Campbell, Shawn M. Arent, Laurent Bannock, Abbie E. Smith-Ryan, Jose Antonio

Publications and Research

Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on a critical analysis of the literature regarding the effects of diet types (macronutrient composition; eating styles) and their influence on body composition. The ISSN has concluded the following. 1) There is a multitude of diet types and eating styles, whereby numerous subtypes fall under each major dietary archetype. 2) All body composition assessment methods have strengths and limitations. 3) Diets primarily focused on fat loss are driven by a sustained caloric deficit. The higher the baseline body fat level, the more aggressively the caloric deficit …

Self-Reported Racial/Ethnic Discrimination And Bronchodilator Response In African American Youth With Asthma, Sonia Carlson, Luisa N. Borrell, Celeste Eng, Myngoc Nguyen, Shannon Thyne, Michael A. Lenoir, Nadine Burke-Harris, Esteban G. Burchard, Neeta Thakur

Publications and Research

Importance Asthma is a multifactorial disease composed of endotypes with varying risk profiles and outcomes. African Americans experience a high burden of asthma and of psychosocial stress, including racial discrimination. It is unknown which endotypes of asthma are vulnerable to racial/ethnic discrimination.

Objective We examined the association between self-reported racial/ethnic discrimination and bronchodilator response (BDR) among African American youth with asthma ages 8 to 21 years (n = 576) and whether this association varies with tumor necrosis factor alpha (TNF-α) level.

Materials and methods Self-reported racial/ethnic discrimination was assessed by a modified Experiences of Discrimination questionnaire as none or any. …

Quality Of General Ed Generally Satisfactory., Aldemaro Romero Jr.

Publications and Research

During the last few years, media have inundated us with bad news about higher education. Whether it is student debt, sexual assaults, or decreased enrollments, colleges and universities seem to be under siege. Add to that the bad press from op-ed writers about political correctness, uselessness of certain degrees, and the fascination with techno- logical fads such as MOOCs, and one can see how controversial higher education has become.

Apparently, someone forgot to ask students what they think.

Now a new national study seems to take care of that. According to a survey conducted with Gallup and Strada Educational Network …

What’S Mine Is Yourls, Junior R. Tidal, Kimberly R. Abrams

Publications and Research

Hyperlink management is critical to website functionality because a site with dead links is not fully operable for the end user. In educational institutions, links used for marketing, course materials, library resources, social media, and other uses can be laborious to maintain in a consistent fashion. Often links are long and unreadable. In order to streamline link maintenance and improve readability for end users, an open source short link manager called YOURLS was implemented at an academic library. In contrast to proprietary shortening services like bit.ly and ow.ly, YOURLS also operates as a link database manager. Long URLs are shortened …

What Impacts Do Oer Have On Students? Students Share Their Experiences With A Health Psychology Oer At New York City College Of Technology, Cailean Cooney

Publications and Research

This article reports findings from a study conducted with students in three sections of a Health Psychology course that replaced a traditional textbook with open educational resources (OER) as the primary course material. The purpose of the study was to learn how OER impacted students. Data were collected in Fall 2015 with students from New York City College of Technology (City Tech), of the City University of New York (CUNY), a comprehensive college located in Brooklyn. Students were assigned the OER by their course instructor, who developed it as part of a library funded OER pilot initiative. Two research instruments …

Narradores Colombianos En Nueva York, Carlos Aguasaco, Carolina Chaves O’Flynn, Alister E. Ramirez, José Jesús Osorio, Carlos Velásquez Torres

Publications and Research

Los quince autores aquí incluidos representan el espectro amplio y diverso de la narrativa colombiana en el área triestatal —New Jersey, New York y Connecticut—. Con casi un millón de colombianos, este triángulo geográfico es parte significativa de nuestra nación. A pesar de la distancia, este grupo de colombianos mantiene y ejerce su colombianidad como parte fundamental de su identidad cultural. La literatura colombiana escrita en la diáspora tiene en esta región una de sus canteras más productivas. Así mismo, los colombianos que conformamos esta comunidad extraterritorial tenemos derecho a hacer parte de la memoria histórica y cultural de la …

Embedded In Technology Ecosystems: Graduate Students, Mobile Devices, And Academic Workflows, Lee Ann Fullington, Frans Albarillo

Publications and Research

This qualitative study uncovers how graduate students use multiple devices to support their academic pursuits, including coursework, group projects, and conducting research. Students often own several devices including smartphones, tablets, laptops, and desktop computers and use these devices in complementary ways to manage workflows, collaborate with colleagues, and support their academic pursuits.

How Much Are Ecuadorians Willing To Pay To Reduce Maternal Mortality? Results From A Pilot Study On Contingent Valuation, Maria-Isabel Roldos, Phaedra Corso, Justin Engel

Publications and Research

Context:

There is an established association between the provision of health care services and maternal mortality. In Ecuador, little is known if the societal value is greater than the resources expended in preventive medicine.

Aims:

The purpose of this research is to investigate Ecuadorians’ willingness to pay to prevent maternal death and disabilities due to complications of care during childbirth in the context of universal coverage.

Methods and Materials:

The study elicited a “contingent” market on morbidity and mortality outcomes, specific to Ecuador’s epidemiologic profiles between a hypothetical market that included a 50% reduction in the risk of maternal mortality …

20th Century Bronx Childhood: Recalling The Faces And Voices, Janet Butler Munch

Publications and Research

A popular photographic exhibit on childhood, originally featured in the Lehman College Art Gallery in the Bronx, New York, was brought to life two decades later through a library digitization grant. The website Childhood in the Bronx features 61 photographs of boys and girls with family or friends, at play, on streets, and in parks, schools, shelters, hospitals, and other locales. Oral history sound excerpts about their childhood, not heard in the original exhibit, complement the 18 vintage photographs shown. The combination of images with the spoken word enhances the user's sensory experience with deeper meaning and enjoyment. This article …