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A Quantitative Synthesis Of The Medicinal Ethnobotany Of The Malinké Of Mali And The Asháninka Of Peru, With A New Theoretical Framework, Nathaniel Bletter

Publications and Research

Background: Although ethnomedically and taxonomically guided searches for new medicinal plants can improve the percentage of plants found containing active compounds when compared to random sampling, ethnobotany has fulfilled little of its promise in the last few decades to deliver a bounty of new, laboratory-proven medicinal plants and compounds. It is quite difficult to test, isolate, and elucidate the structure and mechanism of compounds from the plethora of new medicinal plant uses described each year with limited laboratory time and resources and the high cost of clinical trials of new drug candidates.

Methods: A new quantitative theoretical framework of mathematical …

Pregnancy Intentions And Happiness Among Pregnant Black Women At High Risk For Adverse Infant Health Outcomes, Susan M. Blake, Michele Kiely, Charlotte C. Gard, Ayman El-Mohandes, M. Nabil El-Khorazaty, Nih-Dc Initiative

Publications and Research

CONTEXT:Unintended pregnancy is associated with risk behaviors and increased morbidity or mortality for mothers and infants, but a woman's feelings about pregnancy may be more predictive of risk and health outcomes than her intentions.

METHODS: A sample of 1,044 black women who were at increased risk were enrolled at prenatal care clinics in the District of Columbia in 2001-2003. Bivariate and multivariate analyses assessed associations between pregnancy intentions or level of happiness about being pregnant and multiple psychosocial and behavioral risk factors, and identified correlates of happiness to be pregnant.

RESULTS: Pregnancy intentions and happiness were strongly associated, but …

Reflections On The Reentry Movement., Jeremy Travis

Publications and Research

No abstract provided.

Tempo-Spatial Patterns Of Land Use Changes And Urban Development In Globalizing China: A Study Of Beijing, Yichun Xie, Chuanglin Fang, George C.S. Lin, Hongmian Gong, Biao Qiao

Publications and Research

This study examines the temporal and spatial changes in land use as a consequence of rapid urban development in the city of Beijing. Using a combination of techniques of remote sensing and GIS, the study identifies a substantial loss of plain dryland and a phenomenal expansion of urban construction land over the recent decade. Geographically, there is a clear shifting of urban construction land from the inner city to the outskirts as a consequence of suburbanization. The outward expansion of the ring-road system is found to be one of the most important driving forces explaining the temporal and spatial pattern …

Reasoning About The Behavior Of Aspect-Oriented Programs, Neelam Soundarajan, Raffi Khatchadourian, Johan Dovland

Publications and Research

Aspect-oriented programming (AOP) has become increasingly popular over the last few years. At the same time, reasoning about the behavior of these programs poses serious challenges. In this paper, we present a rely-guarantee approach to such reasoning. The rely-guarantee approach has proven useful in reasoning about concurrent and distributed programs. We show that some of the key problems encountered in reasoning about aspect-oriented programs are similar to those encountered in reasoning about concurrent programs; and that the rely-guarantee approach, appropriately modified, helps address these problems. We illustrate our approach with a simple example.

Permanently Failing Organizations? Small Business Recovery After September 11, 2001, Leigh Graham

Publications and Research

Small businesses in Lower Manhattan after September 11, 2001, paint a telling portrait of vulnerability after disasters. This qualitative analysis of recovery for small retail and service firms with 50 or fewer employees is based on ethnographic fieldwork, interviews, and documentary research from September 2001 through 2005. A postdisaster emphasis on place-based assistance to firms conflicted with macro-level redevelopment plans for Lower Manhattan. Small business recovery was impeded as aid programs responded to a new sense of urgency, attachment to place, and prestorm conceptions of the neighborhood at the expense of addressing community-wide economic changes accelerated by the disaster. Ingredients …

Cell Death In Health And Disease, Richard A. Lockshin, Zahra Zakeri

Publications and Research

Cell death is clearly an important factor in development, homeostasis, pathology and in aging, but medical efforts based on controlling cell death have not become major aspects of medicine. There are several reasons why hopes have been slow to be fulfilled, and they present indications for new directions in research. Most effort has focused on the machinery of cell death, or the proximate effectors of apoptosis and their closely associated and interacting proteins. But cells have many options other than apoptosis. These include autophagy, necrosis, atrophy and stepwise or other alternate means of self-disassembly. The response of a cell to …

An Update On Groundwater Conditions At The Site Of The York College Cuny Campus In Southeastern Queens County, New York City, Nazrul I. Khandaker, Stanley Schleifer, Zarine Ali, Edward A. Molteni

Publications and Research

The wells operated by the Jamaica Water Supply Company in Queens represent the only large scale utilization of groundwater for public water supply in New York City in recent years. These wells were shut down, for the most part, beginning in 1996. Since that time, water table elevations in the area, which had been drawn down by the withdrawal activity of the Jamaica Water Supply Company, have risen significantly causing some high groundwater problems, including flooding of basements. The New York City Department of Environmental Protection (NYCDEP) has held public hearings on a contemplated resumption of ground water withdrawal in …

Contrasting Infection Strategies In Generalist And Specialist Wasp Parasitoids Of Drosophila Melanogaster, Todd A. Schlenke, Jorge Morales, Shubha Govind, Andrew G. Clark

Publications and Research

Although host–parasitoid interactions are becoming well characterized at the organismal and cellular levels, much remains to be understood of the molecular bases for the host immune response and the parasitoids’ ability to defeat this immune response. Leptopilina boulardi and L. heterotoma, two closely related, highly infectious natural parasitoids of Drosophila melanogaster, appear to use very different infection strategies at the cellular level. Here, we further characterize cellular level differences in the infection characteristics of these two wasp species using newly derived, virulent inbred strains, and then use whole genome microarrays to compare the transcriptional response of Drosophila to each. While …

Deafness Mutation Mining Using Regular Expression Based Pattern Matching, Christopher M. Frenz

Publications and Research

Background: While keyword based queries of databases such as Pubmed are frequently of great utility, the ability to use regular expressions in place of a keyword can often improve the results output by such databases. Regular expressions can allow for the identification of element types that cannot be readily specified by a single keyword and can allow for different words with similar character sequences to be distinguished.

Results: A Perl based utility was developed to allow the use of regular expressions in Pubmed searches, thereby improving the accuracy of the searches.

Conclusion: This utility was then utilized to create a …

A Mutation In Mrh2 Kinesin Enhances The Root Hair Tip Growth Defect Caused By Constitutively Activated Rop2 Small Gtpase In Arabidopsis, Guohua Yang, Peng Gao, Hua Zhang, Shanjin Huang, Zhi-Liang Zheng

Publications and Research

Root hair tip growth provides a unique model system for the study of plant cell polarity. Transgenic plants expressing constitutively active (CA) forms of ROP (Rho-of-plants) GTPases have been shown to cause the disruption of root hair polarity likely as a result of the alteration of actin filaments (AF) and microtubules (MT) organization. Towards understanding the mechanism by which ROP controls the cytoskeletal organization during root hair tip growth, we have screened for CA-rop2 suppressors or enhancers using CA1-1, a transgenic line that expresses CA-rop2 and shows only mild disruption of tip growth. Here, we report the characterization of a …

Adverse Effects Of Accounting, Uniformity On Practice, Education And Research, Shyam Sunder

Publications and Research

No abstract provided.

Novel In Silico Method For Teaching Cytoarchitecture, Cellular Diversity, And Gene Expression In The Mammalian Brain, Raddy L. Ramos, Phoebe T. Smith, Joshua C. Brumberg

Publications and Research

Neuroanatomy can be a challenging topic for undergraduates, making the development of new methods of instruction an important goal of neuroscience educators. In the present report we describe the utility and versatility of the Allen Brain Atlas as a novel tool for instruction of several important anatomical principles of the mammalian central nervous system. Using this digital database, we detail how instructors of laboratory or lecture-based courses can demonstrate cytoarchitecture, cellular diversity, and gene expression profiles of the brain.

Northeast Under/Graduate Research Organization For Neuroscience (Neuron): Our Third New York City Meeting, Sharon Ramos Goyette, Kassandra L. Edinger, Vicki Luine, Jason Young, Cheryl A. Frye

Publications and Research

The NorthEast Under/graduate Research Organization for Neuroscience (N.E.U.R.O.N.) promotes preparation, education, and undergraduate research in Neuroscience. The N.E.U.R.O.N. Conference was initially held at undergraduate institutions primarily in New England. Then, for the previous two years, to broaden its impact and increase diversity, the meeting moved to Hunter College, CUNY, New York. This year represents the first year in which two N.E.U.R.O.N. meetings were held, one in Boston and one in New York City. The following is a report of the New York City meeting which was held at Hunter College on April 28, 2007. Eminent Neuroscientist, Dr. Carol Sue Carter, …

Reframing School Dropout As A Public Health Issue, Nicholas Freudenberg, Jessica Ruglis

Publications and Research

Good education predicts good health, and disparities in health and in educational achievement are closely linked. Despite these connections, public health professionals rarely make reducing the number of students who drop out of school a priority, although nearly one-third of all students in the United States and half of black, Latino, and American Indian students do not graduate from high school on time. In this article, we summarize knowledge on the health benefits of high school graduation and discuss the pathways by which graduating from high school contributes to good health. We examine strategies for reducing school dropout rates with …

Cracking Silent Codes: Critical Race Theory And Education Organizing, Celina Su

Publications and Research

Critical race theory (CRT) has moved beyond legal scholarship to critique the ways in which “colorblind” laws and policies perpetuate existing racial inequalities in education policy. While criticisms of CRT have focused on the pessimism and lack of remedies presented, CRT scholars have begun to address issues of praxis. Specifically, communities of color must challenge the dominant narratives of mainstream institutions with alternative visions of pedagogy and school reform, and community organizing plays an important role in helping communities of color to articulate these alternative counter-narratives. Yet, many in education organizing disagree with CRT's critique of colorblindness. Drawing on five …

Two Educator Perspectives On Legal Research Methods, Ellen Boegel, Marissa Moran

Publications and Research

No abstract provided.

Automated Refactoring Of Legacy Java Software To Enumerated Types, Raffi Khatchadourian, Jason Sawin, Atanas Rountev

Publications and Research

Modern Java languages introduce several new features that offer significant improvements over older Java technology. In this article we consider the new enum construct, which provides language support for enumerated types. Prior to recent Java languages, programmers needed to employ various patterns (e.g., the weak enum pattern) to compensate for the absence of enumerated types in Java. Unfortunately, these compensation patterns lack several highly-desirable properties of the enum construct, most notably, type safety. We present a novel fully-automated approach for transforming legacy Java code to use the new enumeration construct. This semantics-preserving approach increases type safety, produces code that is …

Growth Environment And Sex Differences In Lipids, Bodyshape And Diabetes Risk, Mary Schooling, Tai Hing Lam, G. Neil Thomas, Benjamin J. Cowling, Michelle Heys, Edward D. Janus, Gabriel M. Leung

Publications and Research

Background
Sex differences in lipids and body shape, but not diabetes, increase at puberty. Hong Kong Chinese are mainly first or second generation migrants from China, who have shared an economically developed environment for years, but grew up in very different environments in Hong Kong or contemporaneously undeveloped Guangdong, China. We assessed if environment during growth had sex-specific associations with lipids and body shape, but not diabetes.

Methodology and Principal Findings
We used multivariable regression in a population-based cross-sectional study, undertaken from 1994 to 1996, of 2537 Hong Kong Chinese residents aged 25 to 74 years with clinical measurements of …

Recruitment And Retention Of Low-Income Minority Women In A Behavioral Intervention To Reduce Smoking, Depression, And Intimate Partner Violence During Pregnancy, M Nabil El-Khorazaty, Allan A. Johnson, Michele Kiely, Ayman El-Mohandes, Siva Subramanian, Haziel A. Laryea, Kennan B. Murray, Jutta S. Thornberry, Jill G. Joseph

Publications and Research

Background
Researchers have frequently encountered difficulties in the recruitment and retention of minorities resulting in their under-representation in clinical trials. This report describes the successful strategies of recruitment and retention of African Americans and Latinos in a randomized clinical trial to reduce smoking, depression and intimate partner violence during pregnancy. Socio-demographic characteristics and risk profiles of retained vs. non-retained women and lost to follow-up vs. dropped-out women are presented. In addition, subgroups of pregnant women who are less (more) likely to be retained are identified.

Methods
Pregnant African American women and Latinas who were Washington, DC residents, aged 18 years …

Perigenual Anterior Cingulate Morphology Covaries With Perceived Social Standing, Peter J. Gianaros, Jeffrey A. Horenstein, Sheldon Cohen, Karen A. Matthews, Sarah M. Brown, Janine D. Flory, Hugo D. Critchley, Stephen B. Manuck, Ahmad R. Hariri

Publications and Research

Low socioeconomic status (SES) increases the risk for developing psychiatric and chronic medical disorders. A stress-related pathway by which low SES may affect mental and physical health is through the perception of holding a low social standing, termed low subjective social status. This proposal implicates overlapping brain regions mediating stress reactivity and socioemotional behaviors as neuroanatomical substrates that could plausibly link subjective social status to health-related outcomes. In a test of this proposal, we used a computational structural neuroimaging method (voxel-based morphometry) in a healthy community sample to examine the relationships between reports of subjective social status and regional gray …

Review Of The Book The Source: A Guidebook To American Genealogy, 3rd Ed., John A. Drobnicki

Publications and Research

Review of the book The source: A guidebook to American genealogy, 3rd ed.

1139-3159_Nir_Spex, Dagny L. Looper

Publications and Research

No abstract provided.

Nothing New: A Small Enterprise Development Project In West Africa, Aaron Barlow, Bronwyn Hughes

Publications and Research

"This article presents a specific strategy for the aid worker wishing to encourage income-generating enterprises followed by an analysis of the initiation of a construction-supplies business in the north of Togo, West Africa in the late 1980s. This article also stresses project assessment as insurance against failure for the aid organization. Together, these can lead to self-sustaining projects and the furthering of real development."

Nectin-Like Proteins Mediate Axon–Schwann Cell Interactions Along The Internode And Are Essential For Myelination, Patrice Maurel, Steven Einheber, Jolanta Galinska, Pratik Thaker, Isabel Lam, Marina B. Rubin, Steven S. Scherer, Yoshinuri Murakami, David H. Gutmann, James L. Salzer

Publications and Research

Axon–glial interactions are critical for the induction of myelination and the domain organization of myelinated fibers. Although molecular complexes that mediate these interactions in the nodal region are known, their counterparts along the internode are poorly defined. We report that neurons and Schwann cells express distinct sets of nectin-like (Necl) proteins: axons highly express Necl-1 and -2, whereas Schwann cells express Necl-4 and lower amounts of Necl-2. These proteins are strikingly localized to the internode, where Necl-1 and -2 on the axon are directly apposed by Necl-4 on the Schwann cell; all three proteins are also enriched at Schmidt-Lanterman incisures. …

Dust And Smoke: Desertification, Fire And Elephants In Togo, West Africa, Aaron Barlow

Publications and Research

Dust and smoke: from desert and fire. Everyone south of the Sahara in Africa, and not just those in the region where I lived, knows them intimately. From Abidjan to Mombassa, Africans understands what these twinned hazes mean to their lives, their futures. Dual signs of the destruction of the savanna—born of the over-use of farmland and of wood burned as fuel—they’ve become omens, precursors of the desert sands certain to follow. Signals, they are, that life in the villages will only get harder as time passes. This is a story of dust and smoke--and elephants--in one small area in …

Boron And Nitrogen Doped Single Walled Carbon Nanotubes As Possible Dilute Magnetic Semiconductors, Frank J. Owens

Publications and Research

The structure of single walled armchair and zig-zag carbon nanotubes having 70 atoms and two carbons replaced by boron or nitrogen is obtained at minium energy using HF/6-31G* molecular orbital theory. The calculations show that the ground state of the zig-zag tubes is a triplet state while for the armchair tubes it is a singlet. In the zig-zag tubes the density of states at the Fermi level is greater for the spin down states compared to the spin up state indicating that the doped tubes could be ferromagnetic.

Evolution Of Dispersal And Life History Strategies – Tetrahymena Ciliates, Else J. Fjerdingstad, Nicolas Schtickzelle, Pauline Manhes, Arnaud Gutierrez, Jean Clobert

Publications and Research

Background Considerable attention has focused on how selection on dispersal and other core life-history strategies (reproductive effort, survival ability, colonization capacity) may lead to so-called dispersal syndromes. Studies on genetic variation in these syndromes within species could importantly increase our understanding of their evolution, by revealing whether traits co-vary across genetic lineages in the manner predicted by theoretical models, and by stimulating further hypotheses for experimental testing. Yet such studies remain scarce. Here we studied the ciliated protist Tetrahymena thermophila, a particularly interesting organism due to cells being able to transform into morphs differing dramatically in swim-speed. We investigated dispersal, …

Novel Research Translates To Clinical Cases Of Schizophrenic And Cocaine Psychosis, João V. Nunes, Patricia A. Broderick

Publications and Research

Pharmacotherapies for schizophrenic and cocaine psychoses are complex but similar because of similarities in their brain neurochemistry and behavioral outcomes. Their neurochemical neuronal mechanisms of action, as shown in preclinical and clinical studies, involve primarily dopaminergic dysfunction and, secondarily, neuroadaptive effects that seem to involve central serotonergic function. Behavioral outcomes of both disorders include hyperactivity and antipsychotic medications can ameliorate psychotic symptoms. Patients with both disorders often arrive at emergency departments and present floridly psychotic with a predominance of positive symptoms, often prompting physicians to select a typical antipsychotic medication such as haloperidol. While this has become conventional wisdom, we …

A Rotating Panel Survey To Assess Quality Of Hunter College Education, Jennifer Sousa Brennan, William (Bill) H. Williams

Publications and Research

A rotating sample design is proposed to most accurately measure the perceived quality of a Hunter College education. A representative sample of Hunter College students will belong to one of six rotating panels. Students will be contacted during four rotation periods and report their assessment of the two most recent months. It is advantageous to use a rotating panel design as opposed to a fixed panel design in order to guard against the negative effects of a deteriorating response rate. Stratified sampling will help to ensure representation across major departments and academic year of study. Methods for sampling procedures, stratification, …