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Plantar Fasciitis And Calcaneal Spur Formation Are Associated With Abductor Digiti Minimi Atrophy On Mri Of The Foot, Usha Chundru, Amy Liebeskind, Frank Seidelmann, Joshua Fogel, Peter Franklin, Javier Beltran

Publications and Research

Objective To determine the association of atrophy of the abductor digiti minimi muscle (ADMA), an MRI manifestation of chronic compression of the inferior calcaneal nerve suggesting the clinical diagnosis of Baxter’s neuropathy, with MRI markers of potential etiologies, including calcaneal spur formation, plantar fasciitis, calcaneal edema, Achilles tendinosis and posterior tibial tendon dysfunction (PTTD). Materials and methods Prevalence of calcaneal spur formation, plantar fasciitis, calcaneal edema, Achilles tendinosis and PTTD was assessed retrospectively on 100 MRI studies with ADMA and 100 MRI studies without ADMA. Patients ranged in age from 10–92 years. Pearson chi-square analyses and Fisher’s exact test were …

High-Affinity Naloxone Binding To Filamin A Prevents Mu Opioid Receptor–Gs Coupling Underlying Opioid Tolerance And Dependence, Hoau-Yan Wang, Maya Frankfurt, Lindsay H. Burns

Publications and Research

Ultra-low-dose opioid antagonists enhance opioid analgesia and reduce analgesic tolerance and dependence by preventing a G protein coupling switch (Gi/o to Gs) by the mu opioid receptor (MOR), although the binding site of such ultra-low-dose opioid antagonists was previously unknown. Here we show that with approximately 200-fold higher affinity than for the mu opioid receptor, naloxone binds a pentapeptide segment of the scaffolding protein filamin A, known to interact with the mu opioid receptor, to disrupt its chronic opioid-induced Gs coupling. Naloxone binding to filamin A is demonstrated by the absence of [3H]-and FITC-naloxone binding in the melanoma M2 cell …

Changing Corporate Practices To Reduce Cancer Disparities, Nicholas Freudenberg, Sandro Galea, Marianne Fahs

Publications and Research

While reducing racial/ethnic and socioeconomic disparities in cancer mortality has been identified as a national goal, current policies are unlikely to achieve it. In order to advance the development of policies for the primary prevention of cancer and cancer disparities, we propose that the practices of the tobacco, alcohol, and food industries be considered as modifiable social determinants of health. We review evidence that the practices of these industries in product design, marketing, retail distribution, and pricing contribute to cancer risk behavior, incidence, and disparities, then examine public health strategies designed to reduce health-damaging practices of these industries and encourage …

Fourier Series Of Orthogonal Polynomials, Nataniel Greene

Publications and Research

Explicit formulas for the Fourier coefficients of the Legendre polynomials can be found in the Bateman Manuscript Project. However, similar formulas for more general classes of orthogonal polynomials do not appear to have been worked out. Here we derive explicit formulas for the Fourier series of Gegenbauer, Jacobi, Laguerre and Hermite polynomials.

Depression In Parkinson's Disease: Health Risks, Etiology, And Treatment Options, Pasquale G. Frisina, Joan C. Borod, Nancy S. Foldi, Harriet R. Tenenbaum

Publications and Research

Depression is found in about 30%-40% of all patients with Parkinson's disease (PD), but only a small percentage (about 20%) receive treatment. As a consequence, many PD patients suffer with reduced health-related quality of life. To address quality of life in depressed PD patients, we reviewed the literature on the health correlates of depression in PD (eg, cognitive function), etiology of depression in PD, and treatment options (ie, antidepressants, electroconvulsive therapy, and psychotherapy). The current review is unique in its focus on psychosocial aspects, as well as neuropathological factors, of depression in PD. Overall, we conclude that neurochemical (eg, serotonin) …

Childhood Obesity Predicts Adult Metabolic Syndrome: The Fels Longitudinal Study, Shumei S. Sun, Ruohong Liang, Terry T-K Huang, Stephen R. Daniels, Silva Arslanian, Kiang Liu, Gilman D. Grave, Roger M. Siervogel

Publications and Research

Objectives—To determine the age of significant divergence in body mass index (BMI) and waist circumference in adults with and without the metabolic syndrome, and to provide age- and sexspecific childhood values that predict adult metabolic syndrome.

Study design—Part 1 of this study is a retrospective cohort study of 92 men and 59 women (mean age, 51 years) who had metabolic syndrome and 154 randomly selected adults matched for age and sex who did not have the syndrome. Part 2 is a study of predictive accuracy in a validation sample of 743 participants.

Results—The first appearance of differences …

Concourse Dreams: A Bronx Neighborhood And Its Future, William A. Casari

Publications and Research

This master's thesis focuses on the West Bronx recent past and illustrates what upward mobility meant for the Grand Concourse neighborhood populated with second generation immigrant groups at the beginning of the 20th century, including Jewish, Italian and Irish people. Later, most of the same area became a slum at the hands of city planners, New York City administration, and negative media portrayals. Race and ethnicity became even more talked about when non-white immigrants and migrants began moving to the Grand Concourse in huge numbers after World War Two.Through a celebrated Bronx past before 1950 and eventually the sensational media …

The Ethics Of Interrogation And The American Psychological Association: A Critique Of Policy And Process, Brad Olson, Stephen Soldz, Martha Davis

Publications and Research

The Psychological Ethics and National Security (PENS) task force was assembled by the American Psychological Association (APA) to guide policy on the role of psychologists in interrogations at foreign detention centers for the purpose of U.S. national security. The task force met briefly in 2005, and its report was quickly accepted by the APA Board of Directors and deemed consistent with the APA Ethics Code by the APA Ethics Committee. This rapid acceptance was unusual for a number of reasons but primarily because of the APA's long-standing tradition of taking great care in developing ethical policies that protected anyone who …

Does Economic Development Contribute To Sex Differences In Ischaemic Heart Disease Mortality? Hong Kong As A Natural Experiment Using A Case-Control Study, Mary Schooling, Tai Hing Lam, Sai Yin Ho, Kwok Hang Mak, Gabriel M. Leung

Publications and Research

Background
The male excess risk of premature ischemic heart disease (IHD) mortality may be partially due to an unknown macro-environmental influence associated with economic development. We examined whether excess male risk of IHD mortality was higher with birth in an economically developed environment.

Methods
We used multivariable logistic regression in a population-based case-control study of all adult deaths in Hong Kong Chinese in 1998 to compare sex differences in IHD mortality (1,189 deaths in men, 1,035 deaths in women and 20,842 controls) between Hong Kong residents born in economically developed Hong Kong or in contemporaneously undeveloped Guangdong province in China. …

Diverse Antidepressants Increase Cdp-Diacylglycerol Production And Phosphatidylinositide Resynthesis In Depression-Relevant Regions Of The Rat Brain, Kimberly R. Tyeryar, Ashiwel S. Undieh, Habiba Ou Vongtau

Publications and Research

Background: Major depression is a serious mood disorder affecting millions of adults and children worldwide. While the etiopathology of depression remains obscure, antidepressant medications increase synaptic levels of monoamine neurotransmitters in brain regions associated with the disease. Monoamine transmitters activate multiple signaling cascades some of which have been investigated as potential mediators of depression or antidepressant drug action. However, the diacylglycerol arm of phosphoinositide signaling cascades has not been systematically investigated, even though downstream targets of this cascade have been implicated in depression. With the ultimate goal of uncovering the primary postsynaptic actions that may initiate cellular antidepressive signaling, we …

A Technique For Characterizing The Development Of Rhythms In Bird Song, Sigal Saar, Partha P. Mitra

Publications and Research

The developmental trajectory of nervous system dynamics shows hierarchical structure on time scales spanning ten orders of magnitude from milliseconds to years. Analyzing and characterizing this structure poses significant signal processing challenges. In the context of birdsong development, we have previously proposed that an effective way to do this is to use the dynamic spectrum or spectrogram, a classical signal processing tool, computed at multiple time scales in a nested fashion. Temporal structure on the millisecond timescale is normally captured using a short time Fourier analysis, and structure on the second timescale using song spectrograms. Here we use the dynamic …

The Osu1/Qua2/Tsd2-Encoded Putative Methyltransferase Is A Critical Modulator Of Carbon And Nitrogen Nutrient Balance Response In Arabidopsis, Peng Gao, Zeyu Xin, Zhi-Liang Zheng

Publications and Research

The balance between carbon (C) and nitrogen (N) nutrients must be tightly coordinated so that cells can optimize their opportunity for metabolism, growth and development. However, the C and N nutrient balance perception and signaling mechanism remains poorly understood. Here, we report the isolation and characterization of two allelic oversensitive to sugar1 mutants (osu1-1, osu1-2) in Arabidopsis thaliana. Using the cotyledon anthocyanin accumulation and root growth inhibition assays, we show that the osu1 mutants are more sensitive than wild-type to both of the imbalanced C/N conditions, high C/low N and low C/high N. However, under the balanced C/N conditions (low …

Teaching Law In A Multicultural, Multilingual Context, Pamela Edwards, Raquel Gabriel, Donna Lee, David Nadvorney

Publications and Research

No abstract provided.

Resuscitating Proportionality In Non Capital Criminal Sentencing, Donna H. Lee

Publications and Research

No abstract provided.

Judicial Evasion And Disingenuous Legislative Appeals To Science In The Abortion Controversy, Caitlin Borgmann

Publications and Research

No abstract provided.

Resuscitating Proportionality In Noncapital Criminal Sentencing, Donna Lee

Publications and Research

No abstract provided.

The Consequences Of Restricted Health Care Access For Immigrants: Lessons From Medicaid And Schip, Janet Calvo

Publications and Research

No abstract provided.

Confronting Cliches In Online Instruction: Using A Hybrid Model To Teach Lawyering Skills, Joseph Rosenberg

Publications and Research

No abstract provided.

Nicholas Freudenberg: A Selected Bibliography To Accompany A Conversation On Health Law, Julie Graves Krishnaswami

Publications and Research

No abstract provided.

Gender Violence And Work: Reckoning With The Boundaries Of Sex Discrimination Law, Julie Goldscheid

Publications and Research

No abstract provided.

Public School Governance And Democracy: Does Public Participation Matter?, Natalie Gomez-Velez

Publications and Research

No abstract provided.

Servant Of One's Own: The Continuing Class Struggle In Feminist Legal Theories And Practices, Ruthann Robson

Publications and Research

No abstract provided.

Law Clinics And Collective Mobilization, Sameer Ashar

Publications and Research

No abstract provided.

Traditional Advocacy For Nontraditional Youth: Rethinking Best Interest For The Queer Child, Sarah Valentine

Publications and Research

No abstract provided.

Topological And Categorical Properties Of Binary Trees, Homeira Pajoohesh

Publications and Research

Binary trees are very useful tools in computer science for estimating the running time of so-called comparison based algorithms, algorithms in which every action is ultimately based on a prior comparison between two elements. For two given algorithms A and B where the decision tree of A is more balanced than that of B, it is known that the average and worst case times of A will be better than those of B, i.e., ₸A(n) ≤₸B(n) and TWA (n)≤TWB (n). Thus the most balanced and the most imbalanced binary trees play a main role. Here we consider them as semilattices …

Our Existential Death Penalty: Judges, Jurors, And Terror Management, Jeffrey Kirchmeier

Publications and Research

No abstract provided.

Justice Sandra Day O’Connor: A Selected Annotated Bibliography, Julie Graves Krishnaswami

Publications and Research

No abstract provided.

Queer Kids: A Comprehensive Annotated Legal Bibliography On Lesbian, Gay, Bisexual, And Transgender, And Questioning Youth, Sarah Valentine

Publications and Research

No abstract provided.

Trade Winds, Aldemaro Romero Jr., Shelly Kannada

Publications and Research

No abstract provided.

Virgin Islands, Aldemaro Romero Jr., Shelly Kannada

Publications and Research

No abstract provided.