Digital Commons Network^™

High Prevalence Of Obesity Among Inner-City Adolescent Boys In The Bronx, New York: Forgetting Our Boys, Carmen R. Isasi, Amy Whiffen, Yolanda Florez, Katherine Freeman, Judith Wylie-Rosett, Eleanor Campbell

Publications and Research

We examined sex differences in overweight and obesity in a sample of 1,619 inner-city adolescents. Participants were enrolled from 11 public schools in the Bronx, New York. The prevalence of overweight and obesity was 21.7% and 22.5%, respectively; prevalence of obesity was significantly higher among adolescent boys than adolescent girls (24.9 vs 20.1%). Childhood obesity is a public health concern in the United States, and the higher prevalence of obesity in adolescent boys requires additional attention.

Cytomegalovirus Antibodies In Dried Blood Spots: A Minimally Invasive Method For Assessing Stress, Immune Function, And Aging, Jennifer B. Dowd, Allison E. Aiello, Laura Chyu, Yuan-Yen Huang, Thomas W. Mcdade

Publications and Research

Background Cytomegalovirus (CMV) is a prevalent herpesvirus with links to both stress and aging. This paper describes and validates a minimally invasive method for assessing antibodies against CMV in finger stick whole blood spot samples for use as an indirect marker of an aspect of cell-mediated immunity. Results Analysis of CMV in dried blood spot samples (DBS) was based on modifications of a commercially available protocol for quantifying CMV antibodies in serum or plasma. The method was evaluated through analysis of precision, reliability, linearity, and correlation between matched serum and DBS samples collected from 75 volunteers. Correlation between DBS and …

Employing Cogenerative Dialogue To Share Classroom Authority, Edward Lehner

Publications and Research

In America’s high schools, particularly in large urban centers, racial and social class differences separating a teacher and students can create classroom management concerns that could seriously impede upon learning. These classroom management difficulties may branch from the misalignment between a teacher’s instructional methods and students’ learning approaches. This research reports data gathered from a New York City High School Suspension Center during a 9 month school year, including results from 56 focus group interviews and 300 hours of classroom observation. The data analysis reveals that classroom behavioral problems and authority concerns are prominent themes in this school. Informed by …

Reactome: A Database Of Reactions, Pathways And Biological Processes, David Croft, Gavin O’Kelly, Guanming Wu, Robin Haw, Marc Gillespie, Lisa Matthews, Michael Caudy, Phani Garapati, Gopal Gopinath, Bijay Jassal, Steven Jupe, Irina Kalatskaya, Shahana S. Mahajan, Bruce May, Nelson Ndegwa, Esther Schmidt, Veronica Shamovsky, Christina Yung, Ewan Birney, Henning Hermjakob, Peter D’Eustachio, Lincoln Stein

Publications and Research

Reactome (http://www.reactome.org) is a collaboration among groups at the Ontario Institute for Cancer Research, Cold Spring Harbor Laboratory, New York University School of Medicine and The European Bioinformatics Institute, to develop an open source curated bioinformatics database of human pathways and reactions. Recently, we developed a new web site with improved tools for pathway browsing and data analysis. The Pathway Browser is an Systems Biology Graphical Notation (SBGN)-based visualization system that supports zooming, scrolling and event highlighting. It exploits PSIQUIC web services to overlay our curated pathways with molecular interaction data from the Reactome Functional Interaction Network and external interaction …

Heparan Sulfate Proteoglycans Mediate Interstitial Flow Mechanotransduction Regulating Mmp-13 Expression And Cell Motility Via Fak-Erk In 3d Collagen, Zhong-Dong Shi, Hui Wang, John M. Tarbell

Publications and Research

Background Interstitial flow directly affects cells that reside in tissues and regulates tissue physiology and pathology by modulating important cellular processes including proliferation, differentiation, and migration. However, the structures that cells utilize to sense interstitial flow in a 3-dimensional (3D) environment have not yet been elucidated. Previously, we have shown that interstitial flow upregulates matrix metalloproteinase (MMP) expression in rat vascular smooth muscle cells (SMCs) and fibroblasts/myofibroblasts via activation of an ERK1/2-c-Jun pathway, which in turn promotes cell migration in collagen. Herein, we focused on uncovering the flow-induced mechanotransduction mechanism in 3D. Methodology/Principal Findings Cleavage of rat vascular SMC surface …

Connections Between Classical And Parametric Network Entropies, Matthias Dehmer, Abbe Mowshowitz, Frank Emmert-Streib

Publications and Research

This paper explores relationships between classical and parametric measures of graph (or network) complexity. Classical measures are based on vertex decompositions induced by equivalence relations. Parametric measures, on the other hand, are constructed by using information functions to assign probabilities to the vertices. The inequalities established in this paper relating classical and parametric measures lay a foundation for systematic classification of entropy-based measures of graph complexity.

Antibodies Elicited In Response To Ebna-1 May Cross- React With Dsdna, Pragya Yadav, Hoa Tran, Roland Ebegbe, Paul Gottlieb, Hui Wei, Rita H. Lewis, Alice Mumbey-Wafula, Atira Kaplan, Elina Kholdarova, Linda Spatz

Publications and Research

Background:Several genetic and environmental factors have been linked to Systemic Lupus Erythematosus (SLE). One environmental trigger that has a strong association with SLE is the Epstein Barr Virus (EBV). Our laboratory previously demonstrated that BALB/c mice expressing the complete EBNA-1 protein can develop antibodies to double stranded DNA (dsDNA). The present study was undertaken to understand why anti-dsDNA antibodies arise during the immune response to EBNA-1.

Methodology/Principal Findings: In this study, we demonstrated that mouse antibodies elicited in response to EBNA-1 cross-react with dsDNA. First, we showed that adsorption of sera reactive with EBNA-1 and dsDNA, on dsDNA cellulose …

Mtml-Msbayes: Approximate Bayesian Comparative Phylogeographic Inference From Multiple Taxa And Multiple Loci With Rate Heterogeneity, Wen Huang, Naoki Takebayashi, Yan Qi, Michael J. Hickerson

Publications and Research

Background MTML-msBayes uses hierarchical approximate Bayesian computation (HABC) under a coalescent model to infer temporal patterns of divergence and gene flow across codistributed taxon-pairs. Under a model of multiple codistributed taxa that diverge into taxon-pairs with subsequent gene flow or isolation, one can estimate hyper-parameters that quantify the mean and variability in divergence times or test models of migration and isolation. The software uses multi-locus DNA sequence data collected from multiple taxon-pairs and allows variation across taxa in demographic parameters as well as heterogeneity in DNA mutation rates across loci. The method also allows a flexible sampling scheme: different numbers …

Fanm Ayisyen Pap Kase: Respecting The Right To Health Of Haitian Women And Girls, Lisa Davis, Blaine Bookey

Publications and Research

No abstract provided.

Barack Obama And The Public Interest Law Movement: A Preliminary Assessment, Frank Deale, Rita Cant

Publications and Research

No abstract provided.

Very Preterm Birth Is Reduced In Women Receiving An Integrated Behavioral Intervention: A Randomized Controlled Trial, Ayman El-Mohandes, Michele Kiely, Marie G. Gantz, M. Nabil El-Khorazaty

Publications and Research

Background This study examines whether an integrated behavioral intervention with proven efficacy in reducing psycho-behavioral risks (smoking, environmental tobacco smoke exposure (ETSE), depression, and intimate partner violence (IPV)) in African-Americans is associated with improved pregnancy outcomes

Methods A randomized controlled trial targeting risks during pregnancy was conducted in the District of Columbia. African-American women were recruited if reporting at least one of the risks mentioned above. Randomization to intervention or usual care was site and risk specific. Sociodemographic, health risk and pregnancy outcome data were collected. Data on 819 women, and their singleton live born infants were analyzed using an …

Religion, Feminism And Abortion: The Regulation Of Assisted Reproduction In Two Catholic Countries, Richard Storrow

Publications and Research

No abstract provided.

The Ethics Of Exclusion In Infertility Care, Richard Storrow

Publications and Research

No abstract provided.

Improving Clinical Judgment In Lawyering With Multidisciplinary Knowledge About Brain Function And Human Behavior: What Should Law Students Learn About Human Behavior For Effective Lawyering?, Beryl Blaustone

Publications and Research

No abstract provided.

What The Mississippi Personhood Amendment Tells Us About "Life", Caitlin Borgmann

Publications and Research

No abstract provided.

Sustainability: Can Law Meet The Challenge?, Rebecca Bratspies

Publications and Research

No abstract provided.

Burn After Viewing: The Cia's Destruction Of The Abu Zubaydah Tapes And The Law Of Federal Records, Douglas Cox

Publications and Research

No abstract provided.

Still Trembling: State Obligation Under International Law To End Post-Earthquake Rape In Haiti, Lisa Davis

Publications and Research

No abstract provided.

Diversity Dialogues: Finding Common Ground, Raquel Gabriel

Publications and Research

No abstract provided.

From Altruists To Outlaws: The Criminalization Of Traveling Islamic Volunteers, Ramzi Kassem

Publications and Research

No abstract provided.

Scaling The Lexicon Fortress: The United States Supreme Court's Use Of Dictionaries In The Twenty-First Century, Jeffrey Kirchmeier, Samuel A. Thumma

Publications and Research

No abstract provided.

Who Is A Human Rights Defender? An Essay On Sexual And Reproductive Rights Defenders, Cynthia Soohoo

Publications and Research

No abstract provided.

The Full Realization Of Our Rights: The Right To Health In State Constitutions, Cynthia Soohoo

Publications and Research

No abstract provided.

Travel Into The Future Of Reproductive Technology, Richard Storrow

Publications and Research

No abstract provided.

Padilla V. Kentucky: Sound And Fury Or Transformative Potential, Steven Zeidman

Publications and Research

No abstract provided.

Writing About Music: The Challenges Of Teaching Students To Listen Critically, Angelina Tallaj

Publications and Research

No abstract provided.

Dr. Faith Liebl Works To Explain What Cells Do, Aldemaro Romero Jr.

Publications and Research

No abstract provided.

National Archives And International Conflicts: The Society Of American Archivists And War, Douglas Cox

Publications and Research

No abstract provided.

Inalienable Archives: Korean Royal Archives As French Property Under International Law, Douglas Cox

Publications and Research

No abstract provided.

Diversity Dialogues: Managing Conflict, Raquel Gabriel

Publications and Research

No abstract provided.