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Evaluation Of A Medical And Mental Health Unit Compared With Standard Care For Older People Whose Emergency Admission To An Acute General Hospital Is Complicated By Concurrent ‘Confusion’: A Controlled Clinical Trial. Acronym: Team: Trial Of An Elderly Acute Care Medical And Mental Health Unit, Rowan H. Harwood, Sarah E. Goldberg, Kathy H. Whittamore, Catherine Russell, John Rf Gladman, Rob G. Jones, Davina Porock, Sarah A. Lewis, Lucy E. Bradshaw, Rachel A. Elliot

Publications and Research

Background: Patients with delirium and dementia admitted to general hospitals have poor outcomes, and their carers report poor experiences. We developed an acute geriatric medical ward into a specialist Medical and Mental Health Unit over an eighteen month period. Additional specialist mental health staff were employed, other staff were trained in the ‘person-centred’ dementia care approach, a programme of meaningful activity was devised, the environment adapted to the needs of people with cognitive impairment, and attention given to communication with family carers. We hypothesise that patients managed on this ward will have better outcomes than those receiving standard care, and …

Changes In The Regulatory Environment And There Effects On Audits And Auditors, Margaret Ann Wood

Publications and Research

No abstract provided.

Administrative Censoring In Ecological Analyses Of Autism And A Bayesian Solution, Scott M. Bartell, Thomas A. Lewandowski

Publications and Research

Widely cited ecological analyses of autism have reported associations with mercury emissions, with precipitation, and race at the level of counties or school districts. However, state educational agencies often suppress any low numerical autism counts before releasing data—a phenomenon known as “administrative censoring.” Previous analyses did not describe appropriate methods for censored data analysis; common substitution or exclusion methods are known to introduce bias and produce artificially narrow confidence intervals. We apply a Bayesian censored random effects Poisson model to reanalyze associations between 2001 Toxic Release Inventory reported mercury emissions and 2000-2001 autism counts in Texas. Relative risk estimates for …

Melting Trends Over The Greenland Ice Sheet (1958-2009) From Spaceborne Microwave Data And Regional Climate Models, X. Fettweis, Marco Tedesco, M. Van Den Broeke, J. Ettema

Publications and Research

To study near-surface melt changes over the Greenland ice sheet (GrIS) since 1979, melt extent estimates from two regional climate models were compared with those obtained from spaceborne microwave brightness temperatures using two different remote sensing algorithms. The results from the two models were consistent with those obtained with the remote sensing algorithms at both daily and yearly time scales, encouraging the use of the models for analyzing melting trends before the satellite era (1958–1979), when forcing data is available. Differences between satellite-derived and model-simulated results still occur and are used here to identify (i) biases in the snow models …

Roots Of Conflict: A Multi-Level Analysis Of The South Atlantic War Of 1982, David E. Firester

Publications and Research

On 2 April 1982, the Argentinian military had invaded and occupied a series of islands known as the Islas Malvinas, or Falkland Islands.* Subsequently, The United Kingdom had responded with a counter-invasion and occupation in an effort to deny the Argentinian claim of sovereignty over the archipelago. After nearly two months and combat casualties in excess of a thousand soldiers the British military was able to negate the Argentinian success and assert its ownsovereignty over the disputed territories. While the outcome of the dispute is clear, the impetus for its initiation is somewhat murky. This paper will attempt …

Infrapatellar Straps Decrease Patellar Tendon Strain At The Site Of The Jumper’S Knee Lesion, Michael Lavagnino, Steven P. Arnoczky, Julie Dodds, Niell Elvin

Publications and Research

Background: The impetus for the use of patellar straps in the treatment of patellar tendinopathy has largely been based on empirical evidence and not on any mechanistic rationale. A computational model suggests that patellar tendinopathy may be a result of high localized tendon strains that occur at smaller patella–patellar tendon angles (PPTAs). Hypothesis: Infrapatellar straps will decrease the mean localized computational strain in the area of the patellar tendon commonly involved in jumper’s knee by increasing the PPTA. Study Design: Controlled laboratory study. Methods: Twenty adult males had lateral weightbearing and nonweightbearing radiographs of their knees taken with and without …

The Tardy Recognition Of J.S. Bach's Sonatas And Partitas For Violin Solo, Di Su

Publications and Research

J. S. Bach’s Sonatas and Partitas for Violin Solo (BWV 1001-1006) are among the most important masterpieces in the literature of violin music. They are included in standard repertoire for serious violin students; they are frequently performed in solo recitals; they are recorded by numerous virtuosi; and they are required in major violin competitions. The vast amount of editions also indicates the importance of the works. In Edlund’s catalogue, one finds as many as seventy-seven editions ranging from Simrock (1802) to Henle (1987)

However, the Solos did not enjoy such a prominent status in Bach’s own time and even in …

Memorial To Charles Alexander Baskerville (1928–2009), Allen W. Hatheway, Ajitkumar Shah, Joseph J. Lifrieri, Nazrul I. Khandaker, Stanley Schleifer

Publications and Research

Charles Alexander Baskerville captured our imagination, as a senior colleague in the practice of engineering geology in New York City. “Charlie” held the seat of master Big Apple Geologist during his matured career. He was the source, he knew the possibilities, he was aware of the pitfalls of this most geologically complex of American cities. His final work was his greatest reach—the four bedrock geologic quadrangles of the city. Baskerville mapped New York City for more than fifty years. He was sought and given access to sites of bedrock and bedrock/ overburden interface on the various capitol construction projects undertaken …

Metrical Theory And Verdi's Midcentury Operas, William Rothstein

Publications and Research

Both historical and recent theories of meter have tended to assume that meter is a single phenomenon, definable in a single (though perhaps complex) way. Most U.S. theories of meter have been based on a limited repertoire: instrumental music by German composers. Examination of Verdi's mid-century operas, from Macbeth through La traviata (1846–53), suggests that different theoretical approaches may be appropriate for different repertoires. National traditions of composition, depending often on national poetic traditions, may require different ways of hearing and counting, and thus different ways of modeling meter. The metrical theories of Fred Lerdahl and Ray Jackendoff, David Temperley, …

Understanding Depressive Symptoms Among High-Risk Pregnant African American Women, Kristine M. Molina, Michele Kiely

Publications and Research

Much has been written about depression and its risk factors, particularly among women. However, a growing body of literature on prenatal depression has begun to emerge, given that depression during pregnancy presents a major public health concern, since it is found to be a common experience among childbearing aged women (Gaynes et al., 2005; Marcus, 2009). In fact, the onset of depressive symptoms is most likely to occur between 20 to 40 years of age, the range when most women become pregnant (Marcus & Heringhausen, 2009). Further, prior studies have found rates of depression among pregnant women to range from …

Cultures In The Making: An Examination Of The Ethical And Methodological Implications Of Collaborative Research, Chrstina Siry, Carolyne Ali-Khan, Mark Zuss

Publications and Research

This paper explores ethical and methodological implications of collaborative research, and we discuss our examination of ways to work towards participatory, ethical relationships in research. Our core concerns pertain to the experiential, lived and qualitative relations within emergent research communities. Questions that have guided us include: What does "we" mean in research practice? How do we become a community of researchers? What forms of relations are shaped in the continuous process of inquiry? Whose interests are served? How can a community of researchers and their participants, formed and sustained by reciprocal, ethical relations, of trust, shared knowledges, curiosity and friendship, …

Transplantation Of Adult Mouse Ips Cell-Derived Photoreceptor Precursors Restores Retinal Structure And Function In Degenerative Mice, Budd A. Tucker, In-Hyun Park, Sara D. Qi, Henry J. Klassen, Caihui Jiang, Jing Yao, Stephen Redenti, George Q. Daley, Michael J. Young

Publications and Research

This study was designed to determine whether adult mouse induced pluripotent stem cells (iPSCs), could be used to produce retinal precursors and subsequently photoreceptor cells for retinal transplantation to restore retinal function in degenerative hosts. iPSCs were generated using adult dsRed mouse dermal fibroblasts via retroviral induction of the transcription factors Oct4, Sox2, KLF4 and c-Myc. As with normal mouse ES cells, adult dsRed iPSCs expressed the pluripotency genes SSEA1, Oct4, Sox2, KLF4, c-Myc and Nanog. Following transplantation into the eye of immunecompromised retinal degenerative mice these cells proceeded to form teratomas containing tissue comprising all three germ layers. At …

Reflections On Juvenile Justice Reform In New York. Keynote Address Delivered At The Diane Abbey Law Center For Children And Families Conference In New York, Ny Law School., Jeremy Travis

Publications and Research

No abstract provided.

Drug Discovery Using Chemical Systems Biology: Weak Inhibition Of Multiple Kinases May Contribute To The Anti-Cancer Effect Of Nelfinavir, Li Xie, Thomas Evangelidis, Lei Xie, Philip E. Bourne

Publications and Research

Nelfinavir is a potent HIV-protease inhibitor with pleiotropic effects in cancer cells. Experimental studies connect its anti-cancer effects to the suppression of the Akt signaling pathway, but the actual molecular targets remain unknown. Using a structural proteome-wide off-target pipeline, which integrates molecular dynamics simulation and MM/GBSA free energy calculations with ligand binding site comparison and biological network analysis, we identified putative human off-targets of Nelfinavir and analyzed the impact on the associated biological processes. Our results suggest that Nelfinavir is able to inhibit multiple members of the protein kinase-like superfamily, which are involved in the regulation of cellular processes vital …

Physical Activity And Hip Fracture Disability: A Review, Ray Marks

Publications and Research

Objective. The present paper examines pertinent literature sources published in the peer-reviewed English language between 1980 and November 1, 2010 concerning hip fractures. The aim was to highlight potential intervention points to offset the risk of incurring a hip fracture and its attendant disability. Methods. An in-depth search of the literature using the key terms: disability, epidemiology, hip fracture, prevention, and risk factors was conducted, along with data from the author's research base detailing the disability associated with selected hip fracture cases. All articles that dealt with these key topics were reviewed, and relevant data were tabulated and analyzed. Results. …

The Association Of Tree Pollen Concentration Peaks And Allergy Medication Sales In New York City: 2003–2008, Perry E. Sheffield, Kate R. Weinberger, Kazuhiko Ito, Thomas D. Matte, Robert W. Mathes, Guy S. Robinson, Patrick L. Kinney

Publications and Research

The impact of pollen exposure on population allergic illness is poorly characterized. We explore the association of tree pollen and over-the-counter daily allergy medication sales in the New York City metropolitan area. Dates of peak tree pollen (maple, oak, and birch) concentrations were identified from 2003 to 2008. Daily allergy medication sales reported to the city health department were analyzed as a function of the same-day and lagged tree pollen peak indicators, adjusting for season, year, temperature, and day of week. Significant associations were found between tree pollen peaks and allergy medication sales, with the strongest association at 2-day lag …

Fine Particulate Matter Constituents Associated With Cardiovascular Hospitalizations And Mortality In New York City, Kazuhiko Ito, Robert Mathes, Zev Ross, Arthur Nádas, George Thurston, Thomas Matte

Publications and Research

Background Recent time-series studies have indicated that both cardiovascular disease (CVD)mortality and hospitalizations are associated with particulate matter (PM). However, seasonal patterns of PM associations with these outcomes are not consistent, and PM components responsible for these associations have not been determined. We investigated this issue in New York City (NYC), where PM originates from regional and local combustion sources. Objective In this study, we examined the role of particulate matter with aerodynamic diameter ≤ 2.5 μm (PM2.5) and its key chemical components on both CVD hospitalizations and on mortality in NYC. Methods We analyzed daily deaths and emergency hospitalizations …

Dual Testing Algorithm Of Bed-Ceia And Axsym Avidity Index Assays Performs Best In Identifying Recent Hiv Infection In A Sample Of Rwandan Sex Workers, Sarah L. Braunstein, Denis Nash, Andrea A. Kim, Ken Ford, Lambert Mwambarangwe, Chantal M. Ingabire, Joseph Vyankandondera, Janneke H. H. M. Van De Wijgert

Publications and Research

Background

To assess the performance of BED-CEIA (BED) and AxSYM Avidity Index (Ax-AI) assays in estimating HIV incidence among female sex workers (FSW) in Kigali, Rwanda.

Methodology and Findings

Eight hundred FSW of unknown HIV status were HIV tested; HIV-positive women had BED and Ax-AI testing at baseline and ≥12 months later to estimate assay false-recent rates (FRR). STARHS-based HIV incidence was estimated using the McWalter/Welte formula, and adjusted with locally derived FRR and CD4 results. HIV incidence and local assay window periods were estimated from a prospective cohort of FSW. At baseline, 190 HIV-positive women were BED and Ax-AI …

Experimental Tuberculosis In The Wistar Rat: A Model For Protective Immunity And Control Of Infection, Amit Singhal, El Moukhtar Aliouat, Maxime Herve, Vanessa Mathys, Mehdi Kiass, Colette Creusy, Baptiste Delaire, Liana Tsenova, Laurence Fleurisse, Julie Bertout, Luis Camacho, Damian Foo, Hui Chien Tay, Jie Yee Siew, Warda Boukhouchi, Marta Romano, Barun Mathema, Veronique Dartois, Gilla Kaplan, Pablo Bifani

Publications and Research

Background: Despite the availability of many animal models for tuberculosis (TB) research, there still exists a need for better understanding of the quiescent stage of disease observed in many humans. Here, we explored the use of the Wistar rat model for the study of protective immunity and control of Mycobacterium tuberculosis (Mtb) infection.

Methodology/Principal Findings: The kinetics of bacillary growth, evaluated by the colony stimulating assay (CFU) and the extent of lung pathology in Mtb infected Wistar rats were dependent on the virulence of the strains and the size of the infecting inoculums. Bacillary growth control was associated with induction …

A Model Of A Mapk•Substrate Complex In An Active Conformation: A Computational And Experimental Approach, Sunbae Lee, Mangalika Warthaka, Chunli Yan, Tamer S. Kaoud, Andrea Piserchio, Ranajeet Ghose, Pengyu Ren, Kevin N. Dalby

Publications and Research

The mechanisms by which MAP kinases recognize and phosphorylate substrates are not completely understood. Efforts to understand the mechanisms have been compromised by the lack of MAPK-substrate structures. While MAPK-substrate docking is well established as a viable mechanism for bringing MAPKs and substrates into close proximity the molecular details of how such docking promotes phosphorylation is an unresolved issue. In the present study computer modeling approaches, with restraints derived from experimentally known interactions, were used to predict how the N-terminus of Ets-1 associates with ERK2. Interestingly, the N-terminus does not contain a consensus-docking site ((R/K)2-3-X2-6-ΦA-X-ΦB, where Φ is aliphatic hydrophobic) …

Process Evaluation Of The Chicago Juvenile Intervention And Support Center, Jeffrey A. Butts

Publications and Research

Researchers investigated the operations of a pre-court diversion program that provides services and supports to station adjusted youth offenders after contacting the Chicago Police Department but before they have been formally arrested and referred to the Cook County Juvenile Probation Department. The purpose of the study was to determine the suitability of the program for evaluation and to work with staff to enact any procedural modifications that may be needed to facilitate future evaluation activities.

Faculty Of 1000 And Vivo: Invisible Colleges And Team Science, John Carey

Publications and Research

Within the traditional model of scholarly communications, "invisible colleges" facilitate a process of social diffusion that fuels the growth of scientific specialties. This diffusion of ideas operates not through published journal articles but rather through informal communications between researchers. In recent years, researchers have availed themselves of collaborative Web 2.0 forums such as blogs, wikis, and social networking sites to meet their need for increasingly sophisticated vehicles of informal communication. Examinations of the database Faculty of 1000 and the semantic web application VIVO help to illustrate how invisible colleges have migrated to a networked environment where they can play an …

Advances In Optical Biopsy For Cancer Diagnosis, R. R. Alfano

Publications and Research

No abstract provided.

Experiment In Small-Group Homework Tutoring For Remedial Mathematics Students: Preliminary Results, Alice W. Cunningham, Olen Dias, Nieves Angulo

Publications and Research

This paper presents the preliminary results of an 18-section experiment conducted during the Fall 2010 semester regarding the impact of small-group homework-completion tutoring on the performance of Hostos’ remedial mathematics students. The research in question was performed pursuant to a grant, Improving Undergraduate Mathematics Learning: The Effect of Small-Group Homework Tutoring on Remedial Mathematics Learning, from the CUNY Central Office of Academic Affairs. Permission from Hostos’ Institutional Review Board was granted for the conduct of the experiment and for the dissemination of the results.

Review Of The Book Vibrant Matter: A Political Ecology Of Things, Karen Weingarten

Publications and Research

No abstract provided.

Falls Injuries: Causes, Consequences, And Prevention, Ray Marks

Publications and Research

Falls have been and continue to be a leading cause of death among older persons in the United States, affecting at least one in three persons, or as many as one in two persons over 65 years of age each year. This present Special Edition thus sought to examine current research concerning the causes, consequences, and intervention approaches in the context of falls injuries among the elderly.

Not So Fun City, William A. Casari

Publications and Research

This article posits that the destruction of the South Bronx during the 1960s and 1970s was municipally approved across several mayoral administrations, most notably the term of John Lindsay who coined the catch phrase “Fun City,” referring to New York City on the first day of a transit strike. The author outlines several books and articles that detail the destruction caused by fires and city planning decisions that adversely affected White ethnic and neighborhoods of color in the South Bronx. Media portrayals during this period were used to stereotype certain areas of the Bronx which in turn allowed city planners …

Marriage Apartheid And The Tyranny Of American Morality, Shelly J. Eversley

Publications and Research

An essay on implications of marriage equality debates in the Unites States.

Bad Girls And Biopolitics: Abortion, Popular Fiction, And Population Control, Karen Weingarten

Publications and Research

No abstract provided.

Re-Engaging/Engaging Part-Time Librarians, Wilma L. Jones

Publications and Research

In order to maintain high quality service and strengthen retention of part-time librarians, this article addresses ways of engaging new part-time librarians and re-engaging long-time part-time librarians. Part-time librarians are hired primarily to work hours outside the traditional work week or as temporary replacements for unanticipated vacancies, yet they end up providing a third of the service, solely, during evenings and weekends in most small to mid-sized academic institutions. Most are brought in with very little training or orientation to the institution and are expected to hit the ground running while maintaining quality service. This article provides managers with suggestions …