Digital Commons Network^™

A New Twist On The “Un-African” Script: Representing Gay And Lesbian African Weddings In Democratic South Africa, Michael W. Yarbrough

Publications and Research

This essay examines the media coverage surrounding two African weddings of lesbian and gay couples in South Africa, as a lens onto the evolving cultural politics of black queerness in that country. Two decades after South Africa launched a world-leading legal framework for LGBTI protections, I argue that these media representations depict the growing inclusion of black LGBTIQ people as a process of bridging the supposed “gap” between homosexuality and African culture. This new “bridging the gap” script seemingly rejects the older, dominant script portraying homosexuality as intrinsically “un-African.” But I argue that it instead reproduces the “un-African” script in …

Ultrasound-Guided Peripheral Vascular Catheterization In Pediatric Patients: A Narrative Review, Yoshinobu Nakayama, Jun Takeshita, Yasufumi Nakajima, Nobuaki Shime

Publications and Research

Peripheral vascular catheterization (PVC) in pediatric patients is technically challenging. Ultrasound guidance has gained the most interest in perioperative and intensive care fields because it visualizes the exact location of small target vessels and is less invasive than other techniques. There have been a growing number of studies related to ultrasound guidance for PVC with or without difficult access in pediatric patients, and most findings have demonstrated its superiority to other techniques. There are various ultrasound guidance approaches, and a comprehensive understanding of the basics, operator experience, and selection of appropriate techniques is required for the successful utilization of this …

The Association Between Depressive Symptoms And Accumulation Of Stress Among Black Men In The Health And Retirement Study, Roland J. Thorpe, Jr., Ryon Cobb, Keyonna King, Marino A. Bruce, Paul Archibald, Harlan P. Jones, Keith C. Norris, Keith E. Whitfield, Darrell Hudson

Publications and Research

Background and Objectives: Among the multiple factors posited to drive the health inequities that black men experience, the fundamental role of stress in the production of poor health is a key component. Allostatic load (AL) is considered to be a byproduct of stressors related to cumulative disadvantage. Exposure to chronic stress is associated with poorer mental health including depressive symptoms. Few studies have investigated how AL contributes to depressive symptoms among black men. The purpose of the cross-sectional study was to examine the association between AL and depressive symptoms among middle- to old age black men.

Research Design and Methods: …

Exercise Behavior And Mood During The Covid-19 Pandemic In Taiwan: Lessons For The Future, Yu-Kai Chang, Chiao-Ling Hung, Sinika Timme, Sanaz Nosrat, Chien-Heng Chu

Publications and Research

The Coronavirus disease 2019 (COVID-19) pandemic and its associated governmental recommendations and restrictions have influenced many aspects of human life, including exercise and mental health. This study aims to explore the influence of COVID-19 on exercise behavior and its impact on mood states, as well as predict changes in exercise behavior during a similar future pandemic in Taiwan. A cross-sectional online survey was conducted between 7 April and 13 May 2020 (n = 1114). Data on exercise behavior pre and during the pandemic and mood states were collected. A cumulative link model was used to predict changes in exercise frequency …

3,7-Dihydroxytropolones Inhibit Initiation Of Hepatitis B Virus Minus-Strand Dna Synthesis, Ellen Bak, Jennifer T. Miller, Andrea Noronha, John Tavis, Emilio Gallicchio, Ryan P. Murelli, Stuart F. J. Le Grice

Publications and Research

Initiation of protein-primed (-) strand DNA synthesis in hepatitis B virus (HBV) requires interaction of the viral reverse transcriptase with epsilon (ε), a cis-acting regulatory signal located at the 5’ terminus of pre-genomic RNA (pgRNA), and several host-encoded chaperone proteins. Binding of the viral polymerase (P protein) to ε is necessary for pgRNA encapsidation and synthesis of a short primer covalently attached to its terminal domain. Although we identified small molecules that recognize HBV ε RNA, these failed to inhibit protein-primed DNA synthesis. However, since initiation of HBV (-) strand DNA synthesis occurs within a complex of viral and host …

An Approach To Classifying Subjective Cognitive Decline In Community-Dwelling Elders, Laura A. Rabin, Cuilling Wang, Jacqueline A. Mogle, Richard B. Lipton, Carol A. Derby, Mindy J. Katz

Publications and Research

Introduction: Subjective cognitive decline (SCD) may be an early symptomatic man- ifestation of Alzheimer’s disease, though published research largely neglects how to classify SCD in community-based studies.

Methods: In neuropsychologically intact Einstein Aging Study participants (n = 1115; meanage=78;63%female;30%non-White),weusedCoxmodelstoexaminetheasso- ciation between self-perceived cognitive functioning at baseline (using three different approaches) and incident amnestic mild cognitive impairment (aMCI) with covariates of age, sex, education, race/ethnicity, general (objective) cognition, depressive symp- toms, and four other SCD-related features.

Results: After a median of 3 years, 198 participants developed aMCI. In models that included all the variables, self-perceived cognitive functioning was consistently asso- ciated …

When Pandemic Hits: Exercise Frequency And Subjective Well-Being During Covid-19 Pandemic, Ralf Brand, Sinika Timme, Sanaz Nosrat

Publications and Research

The governmental lockdowns related to the COVID-19 pandemic have forced people to change their behavior in many ways including changes in exercise. We used the brief window of global lockdown in the months of March/April/May 2020 as an opportunity to investigate the effects of externally imposed restrictions on exercise-related routines and related changes in subjective well-being. Statistical analyses are based on data from 13,696 respondents in 18 countries using a cross-sectional online survey. A mixed effects modeling approach was used to analyze data. We tested whether exercise frequency before and during the pandemic would influence mood during the pandemic. Additionally, …

Variables And Mechanisms Affecting Response To Language Treatment In Multilingual People With Aphasia, Mira Goral, Aviva Lerman

Publications and Research

Background: Despite substantial literature exploring language treatment effects in multilingual people with aphasia (PWA), inconsistent results reported across studies make it difficult to draw firm conclusions. Methods: We highlight and illustrate variables that have been implicated in effecting cross-language treatment effects in multilingual PWA. Main contribution: We argue that opposing effects of activation and inhibition across languages, influenced by pertinent variables, such as age of language acquisition, patterns of language use, and treatment-related factors, contribute to the complex picture that has emerged from current studies of treatment in multilingual PWA. We propose a new integrated model—Treatment effects in Aphasia in …

The Glycocalyx And Its Role In Vascular Physiology And Vascular Related Diseases, Sheldon Weinbaum, Limary M. Cancel, Bingmei M. Fu, John M. Tarbell

Publications and Research

Purpose—In 2007 the two senior authors wrote a review on the structure and function of the endothelial glycocalyx layer (Weinbaum in Annu Rev Biomed Eng 9:121–167, 2007). Since then there has been an explosion of interest in this hydrated gel-like structure that coats the luminal surface of endothelial cells that line our vasculature due to its important functions in (A) basic vascular physiology and (B) vascular related diseases. This review will highlight the major advances that have occurred since our 2007 paper.

Methods—A literature search mainly focusing on the role of the glycocalyx in the two major areas described above …

Vegan Parents And Children: Zero Parental Compromise, Carlo Alvaro

Publications and Research

Marcus William Hunt argues that, when co-parents disagree over whether to raise their child (or children) as a vegan, they should reach a compromise as a gift given by one parent to the other out of respect for his or her authority. Josh Millburn contends that Hunt’s proposal of parental compromise over veganism is unacceptable on the ground that it overlooks respect for animal rights, which bars compromising. However, he contemplates the possibility of parental compromise over “unusual eating,” of animal-based foods obtained without the violation of animal rights. I argue for zero parental compromise, rejecting a rights-oriented approach, and …

Brand Personality And Sexuality Levels Of Luxury Advertisements, Alyssa Dana Adomaitis, Diana Saiki

Publications and Research

This study examined perceived brand attractiveness of and identification with fashion luxury brands given different levels of sexuality in advertisements. Sex in advertisements has become increasingly more common to generate attention and interest in fashion luxury products with limited research on its influence on the consumer. A sample of 1266 males and females completed a survey on brand attractiveness and identification after examining an advertisement of a luxury fashion product. Participants were assigned an advertisement that featured a same-gendered model at one of four levels of sexuality (fully clothed to nude). The results indicated less sexuality in luxury advertisements was …

Retrieving Functional Pathways Of Biomolecules From Single-Particle Snapshots, Ali Dashti, Ghoncheh Mashayekhi, Mrinal Shekhar, Danya Ben Hail, Salah Salah, Peter Schwander, Amedee Des Georges, Abhishek Singharoy, Joachim Frank, Abbas Ourmazd

Publications and Research

A primary reason for the intense interest in structural biology is the fact that knowledge of structure can elucidate macromolecular functions in living organisms. Sustained effort has resulted in an impressive arsenal of tools for determining the static structures. But under physiological conditions, macromolecules undergo continuous conformational changes, a subset of which are functionally important. Techniques for capturing the continuous conformational changes underlying function are essential for further progress. Here, we present chemically-detailed conformational movies of biological function, extracted data-analytically from experimental single-particle cryo-electron microscopy (cryo-EM) snapshots of ryanodine receptor type 1 (RyR1), a calcium-activated calcium channel engaged in the …

50 Anos De Evolução Nos Estudos Linguísticos Transculturais: Da Retórica Contrastiva À Retórica Intercultural, David Sánchez-Jiménez

Publications and Research

Este trabalho apresenta um panorama histórico dos estudos linguísticos transculturais, discorrendo sobre o surgimento da retórica contrastiva por meio do trabalho seminal de Robert Kaplan em 1966 e as contribuições de Ulla Connor ao rebatizar tais estudos como retórica intercultural. Explana-se também sobre as críticas endereçadas à retórica contrastiva feitas durante os anos 1980, 1990 e 2000 e de que maneira tais críticas redefiniram o quadro teórico-metodológico e o objeto de estudo da disciplina. Conclui-se com exposição de uma crítica à homogeneização das distintas culturas retóricas causada pela globalização e internacionalização do inglês no âmbito acadêmico e nas atividades profissionais.

A Paradigm For Peptide Hormone-Gpcr Analyses, Fred Naider, Jeffrey M. Becker

Publications and Research

Work from our laboratories over the last 35 years that has focused on Ste2p, a G protein-coupled receptor (GPCR), and its tridecapeptide ligand α-factor is reviewed. Our work utilized the yeast Saccharomyces cerevisiae as a model system for understanding peptide-GPCR interactions. It explored the structure and function of synthetic α-factor analogs and biosynthetic receptor domains, as well as designed mutations of Ste2p. The results and conclusions are described using the nuclear magnetic resonance interrogation of synthetic Ste2p transmembrane domains (TMs), the fluorescence interrogation of agonist and antagonist binding, the biochemical crosslinking of peptide analogs to Ste2p, and the phenotypes of …

Association Of Body Shape Index (Absi) With Hand Grip Strength, Nir Y. Krakauer, Jesse C. Krakauer

Publications and Research

Hand grip is a leading measure of muscle strength and general health, yet its association with body shape is not well characterized. Here, we examine correlations between grip strength, a body shape index (ABSI), and body mass index (BMI) in the 2011–2014 United States National Health and Nutrition Examination Survey cohorts. Grip strength was found to correlate negatively with ABSI (though positively with BMI), suggesting that those with a more central body profile tend to be weaker than others with the same weight. Individuals with low grip strength, as well as those with high ABSI, were more likely to die …

Renal Proximal Tubular Nemo Plays A Critical Role In Ischemic Acute Kidney Injury, Sang Jun Han, Ryan M. Williams, Mihwa Kim, Daniel A. Heller, Vivette D'Agati, Marc Schmidt-Supprian, H. Thomas Lee

Publications and Research

We determined that renal proximal tubular (PT) NF-κB essential modulator (NEMO) plays a direct and critical role in ischemic acute kidney injury (AKI) using mice lacking renal PT NEMO and by targeted renal PT NEMO inhibition with mesoscale nanoparticle–encapsulated NEMO binding peptide (NBP MNP). We subjected renal PT NEMO–deficient mice, WT mice, and C57BL/6 mice to sham surgery or 30 minutes of renal ischemia and reperfusion (IR). C57BL/6 mice received NBP MNP or empty MNP before renal IR injury. Mice treated with NBP MNP and mice deficient in renal PT NEMO were protected against ischemic AKI, having decreased renal tubular …

Rate Of Torque Development And Striatal Shape In Individuals With Prodromal Huntington's Disease, Travis Cruickshank, Alvaro Reyes, Timothy S. Pulverenti, Tim Rankin, Danielle M. Bartlett, Anthony J. Blazevich, Govinda Poudel, Mel Ziman, Gabriel S. Trajano

Publications and Research

The aim of the present study was to quantify explosive joint torque or the ability to develop joint torque rapidly, typically measured as the rate of torque development, in individuals with prodromal Huntington’s disease and healthy controls and its associations with measures of disease burden and striatal pathology. Twenty prodromal Huntington’s disease and 19 healthy control individuals volunteered for this study. Plantar flexor isometric rate of torque development values were evaluated using isokinetic dynamometry. Pathological changes in striatal shape were evaluated using magnetic resonance imaging. Disease burden was evaluated using the disease burden score and cytosine-adenine-guanine age product score. No …

Yes, You Can Get A Job With That Major! Goal 5 Strategies For Facilitating, Assessing, And Demonstrating Psychology Students’ Professional Development, Kristin M. Vespia, Karen Z. Naufel, Jerry Rudmann, Jaye F. Van Kirk, Deborah Briihl, Jason Young

Publications and Research

The Summit on the National Assessment of Psychology was held on June 2016 to chart a path for assessing student achievement of the goals of the undergraduate psychology major. Our subcommittee was charged with identifying evaluation strategies and tools for students’ professional development, which included applying psychology to various careers; engaging in effective self-regulation, project management, and teamwork; and developing lifelong professional skills. In this article, therefore, we not only review a wide range of assessment tools for facilitating and evaluating professional development in psychology, but we also discuss the larger importance of the learning goal both to students and …

The Sensitivity Of Repeat And Near Repeat Analysis To Geocoding Algorithms, Cory P. Haberman, David Hatten, Jeremy G. Carter, Eric L. Piza

Publications and Research

Purpose: To determine if repeat and near repeat analysis is sensitive to the geocoding algorithm used for the underlying crime incident data.

Methods: The Indianapolis Metropolitan Police Department provided 2016 crime incident data for five crime types: (1) shootings, (2) robberies, (3) residential burglaries, (4) theft of automobiles, and (5) theft from automobiles. The incident data were geocoded using a dual ranges algorithm and a composite algorithm. First, descriptive analysis of the distances between the two point patterns were conducted. Second, repeat and near repeat analysis was performed. Third, the resulting repeat and near repeat patterns were compared across geocoding …

How Should We Understand The Digital Economy In Asia? Critical Assessment And Research Agenda, Kai Li, Dan J. Kim, Karl R. Lang, Robert J. Kauffman, Maurizio Naldi

Publications and Research

By Asian digital economy, we refer to high-tech developments, business and social transformations, and information- driven changes in the region’s growth. We discuss its background and foundations, significance in Asia and contribution to removal of historical barriers in traditional business. We assess how new value chains are transforming country-level involvement in worldwide manufacturing and note “smiling curve theory” predictions about the global value chain in Asia for high-tech firms and their economies. The takeaway is that the digital economy in Asian nations involves revamping business processes through technology innovation, government policies for growth, and digital entrepreneurship. We analyze the “digital …

Legislation, Linguistics, And Location: Exploring Attitudes On Unauthorized Immigration, David A. Caicedo, Vivienne Badaan

Publications and Research

Contemporary discourse on domestic immigration policy varies widely based on political affiliation, linguistics, and regional differences. This experimental study aimed to concurrently investigate three social psychological bases of attitudes towards unauthorized immigrants in the United States: political ideology, social labels, and social context. Participants were 744 adults, recruited from “New York Community College” (“NYCC”/urban) and “New Jersey Community College” (“NJCC”/suburban), who were randomly assigned to one of two experimental conditions: “illegal” vs. “undocumented”. Participants completed a scale measuring their attitudes towards unauthorized immigrants with the embedded label manipulation, followed by the General System Justification scale, and culminating with demographic items. …

Adapting To Remote Services: Getting Started With A Knowledge Base For Your Users, Sonali Sugrim

Publications and Research

This disruption to usual services as a result of the COVID-19 pandemic forced many librarians to reevaluate the methods with which their users connect with library personnel and library resources. The library is a vital source of information and during these times, it becomes our duty to ensure students and faculty are able to access resources, get research and instructional assistance and be able to continue to do their work with as little disruption as possible. The first step to this would be for the library to organize its contact information, resources and helpful links in one central location, in …

Improving Dental Hygiene Students' Journal Writing, Susan Davide

Publications and Research

During the introductory semester of treating patients, students are in need of assistance and guidance throughout the assessment and treatment phases of patient care. As novice learners, there is little to no prior knowledge on writing a patient case study presentation. To assist and improve dental hygiene student writing of patient case journals, a scaffold assignment was created. Over the course of the semester students were required to submit five patient case studies in the form of a journal. Each journal had a writing focus with specific directions for each along with a detailed rubric; the final journal encompassing all …

Resummation Of Non-Global Logarithms In Cross Sections With Massive Particles, Marcel Balsiger, Thomas Becher, Andrea Ferroglia

Publications and Research

A factorization formalism for jet processes involving massive colored particles such as the top quark is developed, extending earlier results for the massless case. The factorization of soft emissions from the underlying hard process is implemented in an effec tive field theory framework, which forms the basis for the resummation of large logarithms. The renormalization group evolution giving rise to non-global logarithms is implemented into a parton shower code in the large-Nc limit. After a comparison of the massive and massless radiation patterns, the cross section for t¯ t production with a veto on additional central jet activity is computed, …

State And Trait Rumination Effects On Overt Attention To Reminders Of Errors In A Challenging General Knowledge Retrieval Task, Ronald C. Whiteman, Jennifer A. Mangels

Publications and Research

Rumination is a recurrent and repetitive manner of thinking that can be triggered by blockage of personally relevant goals, creating a temporary state of abstract and evaluative self-focus. Particularly when focused on passive “brooding” over one’s problems and feelings, however, rumination can increase negative affect, interfere with problem-solving, and, through a negative feedback cycle, become a chronic trait-like style of responding to personal challenges, particularly in women. Given the pervasiveness of rumination and its potential impact on cognitive processes and emotional states, the present study asks how it impacts attention to feedback that either reminds individuals of goal-state discrepancies (reminders …

Ny Food 20/20: Vision, Research, And Recommendations During Covid-19 And Beyond, The Hunter College Nyc Food Policy Center, The Laurie M. Tisch Center For Food, Education & Policy, The Cuny Urban Food Policy Institute

Publications and Research

The public health and economic implications of the COVID-19 pandemic to the New York City (NYC) food system have been tremendous. In the six months since March 2020, when the pandemic reached NYC’s 5 boroughs, the number of food-insecure individuals has nearly doubled from 1.2 million to 2 million;1 diet quality for many individuals has decreased;2 the local food workforce has lost more than two-thirds of its workers;3 and more than 1,000 NYC restaurants and food retail outlets have closed,4 some never to re-open.

Too often the impacts of a crisis such as COVID-19 are not measured until long after …

Luteolin Induces Cytotoxicity In Mix Cellularity Classical Hodgkin's Lymphoma Via Caspase Activated-Cell Death, Rajendra Gharbaran, Enyuan Shang, Onyekwere Onwumere, Naomi Codrington, Evangelina Dankwa Sarpong, Stephen M. Redenti

Publications and Research

Background/aim: We investigated the effects of luteolin (LUT) on classical Hodgkin's lymphoma (cHL), since such studies in malignant lymphomas are lacking.

Materials and methods: Effect of LUT on cell growth was assessed with water-soluble tetrazolium 1 (WST-1) cell proliferation assay and automated hemocytometry on trypan blue-exclusion assay. Cell death was investigated with acridine orange/ethidium bromide live-dead assay, propidium iodide (PI) flow cytometry, and Annexin-V-PI microscopy. Caspase activation was studied using CellEvent Caspase-3/7 Green detection reagent. High resolution immunofluorescence microscopy was used to detect cleaved-PARP-1.

Results: LUT induced a dose-dependent decrease in the growth of KMH2 and L428 cells, cellular models …

The Quest For Greener Pastures: Evaluating The Livelihoods Impacts Of Providing Vegetation Condition Maps To Pastoralists In Eastern Africa, Elia Machado, Helene Purcell, Andrew M. Simons, Stephanie Swinehart

Publications and Research

The survival of millions of pastoral households in Eastern Africa has become increasingly at risk. Due to mounting socioeconomic and climatic stressors, pastoral households are faced with making migration decisions under increasing uncertainty about resource availability and limited coping strategies. We assess the potential of providing vegetation condition maps to support the migration decision of pastoralists in Ethiopia and Tanzania and the effect of map usage on their herd condition and size. The maps were generated from remotely sensed data using the Normalized Difference Vegetation Index (NDVI) as a proxy for vegetation condition and overlain with pastoralists’ preferred grazing areas. …

Fourteen Recommendations To Create A More Inclusive Environment For Lgbtq+ Individuals In Academic Biology, Katelyn M. Cooper, Anna Jo J. Auerbach, Jordan D. Bader, Amy S. Beadles-Bohling, Jacqueline A. Brashears, Erica Cline, Sarah L. Eddy, Deanna B. Elliott, Elijah Farley, Linda Fuselier, Heather M. Heinz, Madison Irving, Tanya Josek, A. Kelly Lane, Stanley M. Lo, Jeffrey Maloy, Michelle Nugent, Erika Offerdahl, Juan Palacios-Moreno, Jorge Ramos, Joshua W. Reid, Rachel A. Sparks, Ashley L. Waring, Mike Wilton, Cara Gormally, Sara E. Brownell

Publications and Research

Individuals who identify as lesbian, gay, bisexual, transgender, queer, and otherwise non-straight and/or non-cisgender (LGBTQ+) have often not felt welcome or represented in the biology community. Additionally, biology can present unique challenges for LGBTQ+ students because of the relationship between certain biology topics and their LGBTQ+ identities. Currently, there is no centralized set of guidelines to make biology learning environments more inclusive for LGBTQ+ individuals. Rooted in prior literature and the collective expertise of the authors who identify as members and allies of the LGBTQ+ community, we present a set of actionable recommendations to help biologists, biology educators, and biology …

Sharing And Organizing Research Products As R Packages, Matti Vuorre, Matthew J. C. Crump

Publications and Research

A consensus on the importance of open data and reproducible code is emerging. How should data and code be shared to maximize the key desiderata of reproducibility, permanence, and accessibility? Research assets should be stored persistently in formats that are not software restrictive, and documented so that others can reproduce and extend the required computations. The sharing method should be easy to adopt by already busy researchers. We suggest the R package standard as a solution for creating, curating, and communicating research assets. The R package standard, with extensions discussed herein, provides a format for assets and metadata that satisfies …