Digital Commons Network^™

Vaccination With Mage-3a1 Peptide-Pulsed Nature, Monocyte-Derived Dendritic Cells Expands Specific Cytotoxic T Cells And Induces Regression Of Some Metastases In Advanced Stage Iv Melanoma, Beatrice Thurner, Ina Haendle, Claudia Röder

Publications

Dendritic cells (DCs) are considered to be promising adjuvants for inducing immunity to cancer. We used mature, monocyte-derived DCs to elicit resistance to malignant melanoma. The DCs were pulsed with Mage-3A1 tumor peptide and a recall antigens, tetanus toxoid or tuberculin. 11 far advanced stage IV melanoma patients, who were progressive despite standard chemotherapy, received five DC vaccinations at 14-d intervals. The first three vaccinations were administered into the skin, 3 x 10⁶ DCs each subcutaneously and intradermally, followed by two intravenous injections of 6 x 10⁶ and 12 x 10⁶ DCs, respectively. Only minor (less than …

Trance, A Tumor Necrosis Factor Family Member Critical For Cd40 Ligand- Independent T Helper Cell Activation, Martin F. Bachmann, Brian R. Wong, Régis Josien

Publications

CD40 ligand (CD40L), a tumor necrosis factor (TNF) family member, plays a critical role in antigen-specific T cell responses in vivo. CD40L expressed on activated CD4⁺ T cells stimulates antigen-presenting cells such as dendritic cells, resulting in the upregulation of costimulatory molecules and the production of various inflammatory cytokines required for CD4⁺ T cell priming in vivo. However, CD40L- or CD40-deficient mice challenged with viruses mount protective CD4⁺ T cell responses that produce normal levels of interferon γ, suggesting a CD40L/CD40-independent mechanism of CD4⁺ T cell priming that to date has not been elucidated. Here we …

Digital Versus Analog Signal Processing: Effect Of Directional Microphone, Michael Valente, Robert Sweetow, Lisa G. Potts, Becky Bingea

Publications

No abstract provided.

La Gouvernance De Bassin-Versant : Des Limites Naturelles Pour Des Džcisions Relatives Aux Ressources Naturelles, David Getches

Publications

Article written in French and published in a 1999 issue of Espaces et Sociétés journal.

Transforming Experiences: The Benefits Of Intellectual Risk, John Strassburger

Publications

This is the fourth in a series of occasional papers about the challenges confronting students and what Ursinus is doing to help them enter adult life.

Return The Tides Resource Book, Erno Bonebakker, Peter Shelley, Kim Spectre

Publications

No abstract provided.

In Vivo Locomotor Strain In The Hind Limb Bones Of Alligator Mississipiensis And Iguana Iguana: Implications For The Evolution Of Limb Bone Safety Factor And Non-Sprawling Limb Posture., R. W. Blob, A. A. Biewener

Publications

Limb postures of terrestrial tetrapods span a continuum from sprawling to fully upright; however, most experimental investigations of locomotor mechanics have focused on mammals and ground-dwelling birds that employ parasagittal limb kinematics, leaving much of the diversity of tetrapod locomotor mechanics unexplored. This study reports measurements of in vivo locomotor strain from the limb bones of lizard (Iguana iguana) and crocodilian (Alligator mississippiensis) species, animals from previously unsampled phylogenetic lineages with non-parasagittal limb posture and kinematics. Principal strain orientations and shear strain magnitudes indicate that the limb bones of these species experience considerable torsion during locomotion. This contrasts with patterns …

Oxygen In Unevolved Metal-Poor Stars From Keck Ultraviolet Hires Spectra, Ann Merchant Boesgaard, Jeremy R. King, Constantine P. Deliyannis, Steven S. Vogt

Publications

The determination of the abundance of oxygen (O) is important in our understanding of mass–spectrum of previous generations of stars, the evolution of the Galaxy, stellar evolution, and the age-metallicity relation. We have measured O in 24 unevolved stars with Keck HIRES observations of the OH lines in the ultraviolet spectral region at a spectral resolution of ~45,000. The spectra have high signal-to-noise ratios, typically 60–110, and high dispersion, 0.022 Å per pixel. Very special care has been taken in determining the stellar parameters in a consistent way and we have done this for two different, plausible temperature scales. The …

Aboveground Production And Nutrient Circulation Along A Flooding Gradient In A South Carolina Coastal Plain Forest, William Conner, Marianne K. Burke, B Graeme Lockaby

Publications

Relative to effects of flooding, little is known about the influence of hydrology-nutrient interactions on aboveground net primary production (NPP) in forested wetlands. The authors found that nutrient circulation and NPP were closely related along a complex physical, chemical, and hydrologic gradient in a bottomland hardwood forest with four distinct communities. Aboveground biomass, NPP, biomass partitioning to stem production, growth efficiency, and soil macronutrient availability were greatest in the flooded zone, possibly because of the stable hydrologic regime. In the wet transition zone, trees were least productive, nutrient use efficiency was highest, and N retranslocation from foliage before abscission was …

A Gis-Based Analysis And Prediction Of Parcel Land-Use Change In A Coastal Tourism Destination Area, 1999, Jeffery S. Allen, Kang Shou Lu, Thomas D. Potts

Publications

Presented at the 1999 World Congress on Coastal and Marine Tourism, Vancouver, British Columbia, Canada.

American Military Options In A Taiwan Strait Conflict, 1999, Clinton H. Whitehurst Jr.

Publications

No abstract provided.

Clayton, Colgate, & Fishman's Determination Of Gamma-Ray Lines From Supernova Remnants, Donald D. Clayton

Publications

The paper "Gamma-Ray Lines from Young Supernova Remnants" by Clayton, Colgate & Fishman (1969) introduced a realistic observational target for a new wave band of astronomy: nuclear gamma-ray lines that can identifiy newly synthesized nuclei.

Reviewed Work(S): Buenos Aires: Perspectives On The City And Cultural Production Bydavid William Foster, Salvador Oropesa

Publications

No abstract provided.

Insights And Applications Assessing Public Participation In U.S. Watershed Planning Initiatives, Leslie Duram, Katharin G. Brown

Publications

A mail survey of 126 federally funded watershed planning initiatives yielded valid responses from 64 watershed contacts. Quantitative analysis revealed wide variation among watershed initiatives in terms of population size and land area encompassed. Likewise, watershed organization and participation characteristics ( agencies involved, frequency of meetings, and number of active participants) vary greatly. Qualitative analysis delineated the key issues of concern to watershed contacts: agricultural land use, stakeholder awareness, and interaction between local and federal entities. While specific situations vary by watershed, results indicate that door-to-door contact, public meetings, and information programs are the most useful methods for soliciting participation. …

Shipyards And European Shipbuilders In South Carolina (Late 1600s To 1800), Lynn Harris

Publications

This nine page document is one of several in the unpublished 'Occasional Maritime Reseach Papers' series written by Lynn Harris for use by SCIAA.

The document date is approximate.

Muddling Along With The Federal Wealth Transfer Tax: A Survey Of Practitioners And Law School Professors, Wayne M. Gazur

Publications

Recent efforts to repeal the wealth transfer tax system have prompted enormous discussion. In this Article, the author presents the results of his survey of members of the American Bar Association Real Property, Probate and Law Section about this issue and other reforms which have been enacted or suggested.

Three's A Crowd: Law, Literature, And Truth, Marianne Wesson

Publications

No abstract provided.

An Interview With Prafulla Mohanti, Geoffrey Kain

Publications

Prafulla Mohanti was born and brought up in the village of Nanpur, Orissa, India. He lives most of the year in London, but returns to his village, where he owns a home, for a part of every year. Prafulla Mohanti came to England in 1960 after graduating as an architect in Bombay. He worked for a time as architect-town planner for the Greater London Council, but now devotes himself to painting and writing. He has held many exhibitions in England, the U.S., Japan, and Europe, and his paintings are held in a variety of museums and public and private collections. …

Victims' Rights, Rule Of Law, And The Threat To Liberal Jurisprudence, Ahmed A. White

Publications

No abstract provided.

Thermal Plasmaspheric Morphology: Effect Of Geomagnetic And Solar Activity, Mark Anthony Reynolds, G. Ganguli, J.A. Fedder, J. Lemaire, R.R. Meier, D.J. Melendez-Alvira

Publications

A multispecies kinetic model of the thermal plasma in the plasmasphere is used to predict the spatial dependence of the hydrogen ion and helium ion density and temperature for different levels of geomagnetic and solar activity. The particular convection electric field model chosen is intended for the time intervals between substorms. The plasma density and temperature in the equatorial plane are found to exhibit a local-time variation that is sensitive to the details of the convection electric field. In particular, the parallel temperature increases with altitude and the perpendicular temperature decreases with altitude, except in the postmidnight sector, features that …

Rethinking Statutory Antiwaiver Provisions Following The Lloyd's Of London Litigation, Mark J. Loewenstein

Publications

In the Lloyd's of London cases, the United States Courts of Appeals upheld certain forum-selection clauses that effectually deprived investors of the protections of the federal securities laws as if the investors had expressly waived those protections. This article examines statutory antiwaiver provisions in light of the Lloyd's cases, exploring the effect those provisions have on the administration of the federal securities laws, and suggests that the law be amended to allow contractual waiver in certain circumstances.

Do They Practice What We Teach?: A Survey Of Practitioners And Estate Planning Professors, Wayne M. Gazur

Publications

This article presents the results of a 1998 mail survey sent to members of the American Bar Association Real Property, Probate & Trust Law Section and to law professors teaching estate planning. The principal goal of the survey was to compare the opinions of practitioners and law professors concerning the importance of 31 estate planning issues and techniques. The survey also included an open-ended solicitation of issues deemed significant by the participant.

The survey found consistency between practitioner and professor responses with respect to techniques such as Crummey planning. Legal education appears to be effective in dealing with core principles. …

Dedication: Professor Albert E. Utton (1931-1998), David H. Getches

Publications

No abstract provided.

Interpreting Indian Country In State Of Alaska V. Native Village Of Venetie, Kristen A. Carpenter

Publications

According to federal Indian law's canons of construction, statutes enacted for the benefit of American Indians and Alaska Natives must be liberally interpreted in their favor. But a doctrine of statutory interpretation presently challenges certain applications of the Indian canons. Announced by the Supreme Court in Chevron, U.S.A. v. Natural Resources Defense Council, Inc., the doctrine requires that courts defer to administrative agency interpretations of ambiguous language in statutes they are authorized to administer. In instances where agencies construe statutes against Indian interests, Chevron deference and the Indian canons dictate opposite results for a reviewing court. This conflict muddles Indian …

Shareholder Derivative Litigation And Corporate Governance, Mark J. Loewenstein

Publications

In approving settlements of derivative actions that include fees for plaintiff's attorney, courts typically announce that attorney's fees are approved if a substantial benefit is obtained. In fact, courts, particularly Delaware courts, approve settlements in shareholder derivative actions that included substantial fees for plaintiff's attorney, despite the absence of a corresponding benefit to the corporation. Frequently, the "benefit" obtained is a reform in corporate governance, which is of dubious value to the corporation. To deter frivolous litigation, courts should resist the temptation to approve these settlements just to dispose of the litigation. The paper concludes that fees should not be …

The Roth Ira Cuts Federal Revenues, With No Benefit To Taxpayers, Michael Waggoner

Publications

No abstract provided.

Lies And Law, Robert F. Nagel

Publications

No abstract provided.

Site Index Of Balsam Poplar/Western Black Cottonwood In Interior And Southcentral Alaska, John D. Shaw, Edmond C. Packee

Publications

Stem analysis data were obtained from 268 balsam poplar (populus balsamifera L.) and black cottonwood (P. trichocarpa Torr. & Gray) trees on 67 sites in interior and southcentral Alaska during 1988-1990 for the purpose of height and volume growth analysis. A modifiedform of the Chapman-Richards growth model was used to produce polymorphic site index curves. Wide variations in curve shape, which were evident in region-to-region comparisons, required stratification ofthe data. Site index curves for balsam poplar north ofthe Alaska Range were produced using one equation and data from 35 sites. The remaining 32 sites, located south ofthe Range, were divided …

Site Index Of Balsam Poplar/Western Black Cottonwood In Interior And Southcentral Alaska, John D. Shaw, Edmond C. Packee

Publications

Stem analysis data were obtained from 268 balsam poplar (populus balsamifera L.) and black cottonwood (P. trichocarpa Torr. & Gray) trees on 67 sites in interior and southcentral Alaska during 1988-1990 for the purpose of height and volume growth analysis. A modifiedform of the Chapman-Richards growth model was used to produce polymorphic site index curves. Wide variations in curve shape, which were evident in region-to-region comparisons, required stratification ofthe data. Site index curves for balsam poplar north ofthe Alaska Range were produced using one equation and data from 35 sites. The remaining 32 sites, located south ofthe Range, were divided …

The Economic Situation, 1998 December, Bruce Yandle

Publications

Quarterly report on the economic situation of the United States and South Carolina.