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Enhancing Lysosome Biogenesis Attenuates Bnip3-Induced Cardiomyocyte Death, Xiucui Ma, Rebecca J. Godar, Haiyan Liu, Abhinav Diwan Jan 2012

Enhancing Lysosome Biogenesis Attenuates Bnip3-Induced Cardiomyocyte Death, Xiucui Ma, Rebecca J. Godar, Haiyan Liu, Abhinav Diwan

Open Access Publications

No abstract provided.


Cancer Control Needs Of 2-1-1 Callers In Missouri, North Carolina, Texas, And Washington, Jason Q. Purnell, Matthew W. Kreuter, Katherine S. Eddens, Kurt M. Ribisl, Peggy Hannon, Rebecca S. Williams, Marie E. Fernandez, David Jobe, Susan Gemmel, Marti Morris, Debbie Fagin Jan 2012

Cancer Control Needs Of 2-1-1 Callers In Missouri, North Carolina, Texas, And Washington, Jason Q. Purnell, Matthew W. Kreuter, Katherine S. Eddens, Kurt M. Ribisl, Peggy Hannon, Rebecca S. Williams, Marie E. Fernandez, David Jobe, Susan Gemmel, Marti Morris, Debbie Fagin

Open Access Publications

No abstract provided.


Tools For Implementing An Evidence-Based Approach In Public Health Practice, Julie A. Jacobs, Ellen Jones, Barbara A. Gabella, Bonnie Spring, Ross C. Brownson Jan 2012

Tools For Implementing An Evidence-Based Approach In Public Health Practice, Julie A. Jacobs, Ellen Jones, Barbara A. Gabella, Bonnie Spring, Ross C. Brownson

Open Access Publications

No abstract provided.


Coronary Ct Angiography Versus Standard Evaluation In Acute Chest Pain, Pamela Woodard, Michael E. Mullins, Et Al Jan 2012

Coronary Ct Angiography Versus Standard Evaluation In Acute Chest Pain, Pamela Woodard, Michael E. Mullins, Et Al

Open Access Publications

No abstract provided.


Lenalidomide After Stem-Cell Transplantation For Multiple Myeloma, Ravi Viji, Et Al Jan 2012

Lenalidomide After Stem-Cell Transplantation For Multiple Myeloma, Ravi Viji, Et Al

Open Access Publications

No abstract provided.


Enzyme-Replacement Therapy In Life-Threatening Hypophosphatasia, Michael P. Whyte, William H. Mcalister, Et Al Jan 2012

Enzyme-Replacement Therapy In Life-Threatening Hypophosphatasia, Michael P. Whyte, William H. Mcalister, Et Al

Open Access Publications

No abstract provided.


The Incidence Of Bifid C7 Spinous Processes, Woojin Cho, Takeshi Maeda, Yung Park, Jacob M. Buchowski, Colin E. Nabb, K. D. Riew Jan 2012

The Incidence Of Bifid C7 Spinous Processes, Woojin Cho, Takeshi Maeda, Yung Park, Jacob M. Buchowski, Colin E. Nabb, K. D. Riew

Open Access Publications

No abstract provided.


Cannabis Or Alcohol First? Differences By Ethnicity And In Risk For Rapid Progression To Cannabis-Related Problems In Women, C. E. Sartor, A. Agrawal, M. T. Lynskey, A. E. Duncan, J. D. Grant, E. C. Nelson, P. A. Madden, A. C. Heath, K. K. Bucholz Jan 2012

Cannabis Or Alcohol First? Differences By Ethnicity And In Risk For Rapid Progression To Cannabis-Related Problems In Women, C. E. Sartor, A. Agrawal, M. T. Lynskey, A. E. Duncan, J. D. Grant, E. C. Nelson, P. A. Madden, A. C. Heath, K. K. Bucholz

Open Access Publications

No abstract provided.


Changing Epidemiology Of Methicillin-Resistant Staphylococcus Aureus Colonization In Paediatric Intensive-Care Units, C. R. Hermos, T. J. Sandora, L. E. Williams, N. Mosammaparast, A. J. Mcadam Jan 2012

Changing Epidemiology Of Methicillin-Resistant Staphylococcus Aureus Colonization In Paediatric Intensive-Care Units, C. R. Hermos, T. J. Sandora, L. E. Williams, N. Mosammaparast, A. J. Mcadam

Open Access Publications

No abstract provided.


Bnip3 Regulates Mitochondrial Function And Lipid Metabolism In The Liver, Danielle Glick, Wenshuo Zhang, Michelle Beaton, Glenn Marsboom, Michaela Gruber, M. Celeste Simon, John Hart, Gerald W. Dorn Ii, Matthew J. Brady, Kay F. Macleod Jan 2012

Bnip3 Regulates Mitochondrial Function And Lipid Metabolism In The Liver, Danielle Glick, Wenshuo Zhang, Michelle Beaton, Glenn Marsboom, Michaela Gruber, M. Celeste Simon, John Hart, Gerald W. Dorn Ii, Matthew J. Brady, Kay F. Macleod

Open Access Publications

No abstract provided.


The Ampk Β2 Subunit Is Required For Energy Homeostasis During Metabolic Stress, Biplab Diasgupta, Jeong Sun Ju, Yo Sasaki, Xiaona Liu, Su-Ryun Jung, Kazuhiko Higashida, Diana Lindquist, Jeffrey Milbrandt Jan 2012

The Ampk Β2 Subunit Is Required For Energy Homeostasis During Metabolic Stress, Biplab Diasgupta, Jeong Sun Ju, Yo Sasaki, Xiaona Liu, Su-Ryun Jung, Kazuhiko Higashida, Diana Lindquist, Jeffrey Milbrandt

Open Access Publications

No abstract provided.


Interaction Of Cyclin-Dependent Kinase 12/Crkrs With Cyclin K1 Is Required For The Phosphorylation Of The C-Terminal Domain Of Rna Polymerase Ii, S.-W. Grace Cheng, Michael A. Kuzyk, Annie Moradian, Taka-Aki Ichu, Vicky C.-D. Chang, Jerry F. Tien, Sarah E. Vollett, Malachi Griffith, Marco A. Marra, Gregg B. Morin Jan 2012

Interaction Of Cyclin-Dependent Kinase 12/Crkrs With Cyclin K1 Is Required For The Phosphorylation Of The C-Terminal Domain Of Rna Polymerase Ii, S.-W. Grace Cheng, Michael A. Kuzyk, Annie Moradian, Taka-Aki Ichu, Vicky C.-D. Chang, Jerry F. Tien, Sarah E. Vollett, Malachi Griffith, Marco A. Marra, Gregg B. Morin

Open Access Publications

No abstract provided.


Re-Orientation Of Clinical Research In Traumatic Brain Injury: Report Of An International Workshop On Comparative Effectiveness Research, Andrew I.R. Maas, David K. Menon, Hester F. Lingsma, Jose A. Pineda, M. Elizabeth Sandel, Geoffery T. Manley Jan 2012

Re-Orientation Of Clinical Research In Traumatic Brain Injury: Report Of An International Workshop On Comparative Effectiveness Research, Andrew I.R. Maas, David K. Menon, Hester F. Lingsma, Jose A. Pineda, M. Elizabeth Sandel, Geoffery T. Manley

Open Access Publications

No abstract provided.


Should One Measure Balance Or Gait To Best Predict Falls Among People With Parkinson Disease?, Ryan P. Duncan, Gammon M. Earhart Jan 2012

Should One Measure Balance Or Gait To Best Predict Falls Among People With Parkinson Disease?, Ryan P. Duncan, Gammon M. Earhart

Open Access Publications

No abstract provided.


Human Cytomegalovirus Pul29/28 And Pul38 Repression Of P53-Regulated P21cip1 And Caspase 1 Promoters During Infection, John P. Savaryn, Justin M. Reitsma, Tarin M. Bigley, Brian D. Halligan, Zhikang Xian, Dong Yu, Scott S. Terhune Jan 2012

Human Cytomegalovirus Pul29/28 And Pul38 Repression Of P53-Regulated P21cip1 And Caspase 1 Promoters During Infection, John P. Savaryn, Justin M. Reitsma, Tarin M. Bigley, Brian D. Halligan, Zhikang Xian, Dong Yu, Scott S. Terhune

Open Access Publications

No abstract provided.


Essential Cell-Autonomous Role For Interferon (Ifn) Regulatory Factor 1 In Ifn-Γ-Mediated Inhibition Of Norovirus Replication In Macrophages, Nicole S. Maloney, Larissa B. Thackray, Gautam Goel, Seungmin Hwang, Erning Duan, Punit Vachharajani, Ramnik Xavier, Herbert W. Virgin Jan 2012

Essential Cell-Autonomous Role For Interferon (Ifn) Regulatory Factor 1 In Ifn-Γ-Mediated Inhibition Of Norovirus Replication In Macrophages, Nicole S. Maloney, Larissa B. Thackray, Gautam Goel, Seungmin Hwang, Erning Duan, Punit Vachharajani, Ramnik Xavier, Herbert W. Virgin

Open Access Publications

No abstract provided.


Critical Role For Interferon Regulatory Factor 3 (Irf-3) And Irf-7 In Type I Interferon-Mediated Control Of Murine Norovirus Replication, Larissa B. Thackray, Erning Duan, Helen M. Lazear, Amal Kambal, Robert D. Schreiber, Michael S. Diamond, Herbert W. Virgin Jan 2012

Critical Role For Interferon Regulatory Factor 3 (Irf-3) And Irf-7 In Type I Interferon-Mediated Control Of Murine Norovirus Replication, Larissa B. Thackray, Erning Duan, Helen M. Lazear, Amal Kambal, Robert D. Schreiber, Michael S. Diamond, Herbert W. Virgin

Open Access Publications

No abstract provided.


Adaptive Immunity Restricts Replication Of Novel Murine Astroviruses, Christine C. Yokoyama, Joy Loh, Guoyan Zhao, Thaddeus S. Stappenbeck, David Wang, Henry V. Huang, Herbert W. Virgin, Larissa B. Thackray Jan 2012

Adaptive Immunity Restricts Replication Of Novel Murine Astroviruses, Christine C. Yokoyama, Joy Loh, Guoyan Zhao, Thaddeus S. Stappenbeck, David Wang, Henry V. Huang, Herbert W. Virgin, Larissa B. Thackray

Open Access Publications

No abstract provided.


Decreased Functional Connectivity Between The Amygdala And The Left Ventral Prefrontal Cortex In Treatment-Naive Patients With Major Depressive Disorder: A Resting-State Functional Magnetic Resonance Imaging Study, Y. Tang, L. Kong, F. Womer, W. Jiang, Y. Cao, L. Ren, J. Wang, G. Fan, H. P. Blumberg, K. Xu, F. Wang Jan 2012

Decreased Functional Connectivity Between The Amygdala And The Left Ventral Prefrontal Cortex In Treatment-Naive Patients With Major Depressive Disorder: A Resting-State Functional Magnetic Resonance Imaging Study, Y. Tang, L. Kong, F. Womer, W. Jiang, Y. Cao, L. Ren, J. Wang, G. Fan, H. P. Blumberg, K. Xu, F. Wang

Open Access Publications

No abstract provided.


Effect Of (Neo)Adjuvant Zoledronic Acid On Disease-Free And Overall Survival In Clinical Stage Ii/Iii Breast Cancer, Rebecca L. Aft, Michael J. Naughton, Kathryn M. Trinkaus, Katherine N. Weilbaecher Jan 2012

Effect Of (Neo)Adjuvant Zoledronic Acid On Disease-Free And Overall Survival In Clinical Stage Ii/Iii Breast Cancer, Rebecca L. Aft, Michael J. Naughton, Kathryn M. Trinkaus, Katherine N. Weilbaecher

Open Access Publications

No abstract provided.


Sigma-2 Ligands Induce Tumour Cell Death By Multiple Signalling Pathways, Chenbo Zeng, Justin M. Rothfuss, Jun Zhang, Wenhua Chu, Suwanna Vangveravong, Zhude Tu, Fenghui Pan, Katherine Chang, Richard S. Hotchkiss, Robert H. Mach Jan 2012

Sigma-2 Ligands Induce Tumour Cell Death By Multiple Signalling Pathways, Chenbo Zeng, Justin M. Rothfuss, Jun Zhang, Wenhua Chu, Suwanna Vangveravong, Zhude Tu, Fenghui Pan, Katherine Chang, Richard S. Hotchkiss, Robert H. Mach

Open Access Publications

No abstract provided.


Bone Marrow Transplantation Alters The Tremor Phenotype In The Murine Model Of Globoid-Cell Leukodystrophy, Adarsh S. Reddy, David F. Wozniak, Nuri B. Farber, Joshua T. Dearborn, Stephen C. Fowler, Mark S. Sands Jan 2012

Bone Marrow Transplantation Alters The Tremor Phenotype In The Murine Model Of Globoid-Cell Leukodystrophy, Adarsh S. Reddy, David F. Wozniak, Nuri B. Farber, Joshua T. Dearborn, Stephen C. Fowler, Mark S. Sands

Open Access Publications

No abstract provided.


Quantitative Brain Electrical Activity In The Initial Screening Of Mild Traumatic Brain Injuries, Brian O'Neil, Leslie S. Prichep, Roseanne Naunhemi, Robert Chabot Jan 2012

Quantitative Brain Electrical Activity In The Initial Screening Of Mild Traumatic Brain Injuries, Brian O'Neil, Leslie S. Prichep, Roseanne Naunhemi, Robert Chabot

Open Access Publications

No abstract provided.


Validation Of Self-Reported Measures In Health Disparities Research, Bertha Hidalgo, Melody Goodman Jan 2012

Validation Of Self-Reported Measures In Health Disparities Research, Bertha Hidalgo, Melody Goodman

Open Access Publications

No abstract provided.


Missing Data Methods For Partial Correlations, Gina M. D'Angelo, Jingqin Luo, Chengjie Xiong Jan 2012

Missing Data Methods For Partial Correlations, Gina M. D'Angelo, Jingqin Luo, Chengjie Xiong

Open Access Publications

No abstract provided.


Structure Of A Bacterial Voltage-Gated Sodium Channel Pore Reveals Mechanisms Of Opening And Closing, Emily C. Mccusker, Claire Bagnéris, Claire E. Naylor, Ambrose R. Cole, Nazzareno D'Avanzo, Colin G. Nichols, B A. Wallace Jan 2012

Structure Of A Bacterial Voltage-Gated Sodium Channel Pore Reveals Mechanisms Of Opening And Closing, Emily C. Mccusker, Claire Bagnéris, Claire E. Naylor, Ambrose R. Cole, Nazzareno D'Avanzo, Colin G. Nichols, B A. Wallace

Open Access Publications

No abstract provided.


Plasmodium Falciparum  Heat Shock Protein 110 Stabilizes The Asparagine Repeat-Rich Parasite Proteome During Malarial Fevers, Vasant Muralidharan, Anna Oksman, Priya Pal, Susan Lindquist, Daniel E. Goldberg Jan 2012

Plasmodium Falciparum  Heat Shock Protein 110 Stabilizes The Asparagine Repeat-Rich Parasite Proteome During Malarial Fevers, Vasant Muralidharan, Anna Oksman, Priya Pal, Susan Lindquist, Daniel E. Goldberg

Open Access Publications

No abstract provided.


Administration Of Cog1410 Reduces Axonal Amyloid Precursor Protein Immunoreactivity And Microglial Activation After Controlled Cortical Impact In Mice, Yong Jiang, David L. Brody Jan 2012

Administration Of Cog1410 Reduces Axonal Amyloid Precursor Protein Immunoreactivity And Microglial Activation After Controlled Cortical Impact In Mice, Yong Jiang, David L. Brody

Open Access Publications

No abstract provided.


Micrornas Are Exported From Malignant Cells In Customized Particles, Jaime Palma, Scree C. Yaddanapudi, Lucy Pigati, Mallory A. Havens, Sarah Jeong, Geoffrey A. Weiner, Kristina Mary Ellen Weimer, Brittany Stern, Michelle L. Hastings, Dominik M. Duelli Jan 2012

Micrornas Are Exported From Malignant Cells In Customized Particles, Jaime Palma, Scree C. Yaddanapudi, Lucy Pigati, Mallory A. Havens, Sarah Jeong, Geoffrey A. Weiner, Kristina Mary Ellen Weimer, Brittany Stern, Michelle L. Hastings, Dominik M. Duelli

Open Access Publications

No abstract provided.


Structural Insight Into Mr1-Mediated Recognition Of The Mucosal Associated Invariant T Cell Receptor, Rangsima Reantragoon, Lars Kjer-Nielsen, Onisha Patel, Zhenjun Chen, Patricia T. Illing, Mugdha Bhati, Lyudmila Kostenko, Mandvi Bharadwaj, Bronwyn Meehan, Ted H. Hansen, Dale I. Godfrey, Jamie Rossjohn, James Mccluskey Jan 2012

Structural Insight Into Mr1-Mediated Recognition Of The Mucosal Associated Invariant T Cell Receptor, Rangsima Reantragoon, Lars Kjer-Nielsen, Onisha Patel, Zhenjun Chen, Patricia T. Illing, Mugdha Bhati, Lyudmila Kostenko, Mandvi Bharadwaj, Bronwyn Meehan, Ted H. Hansen, Dale I. Godfrey, Jamie Rossjohn, James Mccluskey

Open Access Publications

Mucosal-associated invariant T (MAIT) cells express a semiinvariant αβ T cell receptor (TCR) that binds MHC class I-like molecule (MR1). However, the molecular basis for MAIT TCR recognition by MR1 is unknown. In this study, we present the crystal structure of a human Vα7.2Jα33-Vβ2 MAIT TCR. Mutagenesis revealed highly conserved requirements for the MAIT TCR-MR1 interaction across different human MAIT TCRs stimulated by distinct microbial sources. Individual residues within the MAIT TCR β chain were dispensable for the interaction with MR1, whereas the invariant MAIT TCR α chain controlled specificity through a small number of residues, which are conserved across …