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Articles 4981 - 5010 of 5949
Full-Text Articles in Entire DC Network
Integrated Genomics Of Susceptibility To Alkylator-Induced Leukemia In Mice, Patrick Cahan, Timothy A. Graubert
Integrated Genomics Of Susceptibility To Alkylator-Induced Leukemia In Mice, Patrick Cahan, Timothy A. Graubert
Open Access Publications
No abstract provided.
Hidden Markov Model Speed Heuristic And Iterative Hmm Search Procedure, L Steven Johnson, Sean R. Eddy, Elon Portugaly
Hidden Markov Model Speed Heuristic And Iterative Hmm Search Procedure, L Steven Johnson, Sean R. Eddy, Elon Portugaly
Open Access Publications
No abstract provided.
Novel Venom Gene Discovery In The Platypus, Camilla M. Whittington, Anthony T. Papenfuss, Devin P. Locke, Elaine R. Mardis, Richard K. Wilson, Sahar Abubucker, Makedonka Mitreva, Emily Sw Wong, Arthur L. Hsu, Philip W. Kuchel, Katherine Belov, Wesley C. Warren
Novel Venom Gene Discovery In The Platypus, Camilla M. Whittington, Anthony T. Papenfuss, Devin P. Locke, Elaine R. Mardis, Richard K. Wilson, Sahar Abubucker, Makedonka Mitreva, Emily Sw Wong, Arthur L. Hsu, Philip W. Kuchel, Katherine Belov, Wesley C. Warren
Open Access Publications
No abstract provided.
The Novel Sigma-2 Receptor Ligand Sw43 Stabilizes Pancreas Cancer Progression In Combination With Gemcitabine, John R. Hornick, Jinbin Xu, Suwanna Vangveravong, Zhude Tu, Jonathan B. Mitchem, Dirk Spitzer, Peter Goedegebuure, Robert H. Mach, William G. Hawkins
The Novel Sigma-2 Receptor Ligand Sw43 Stabilizes Pancreas Cancer Progression In Combination With Gemcitabine, John R. Hornick, Jinbin Xu, Suwanna Vangveravong, Zhude Tu, Jonathan B. Mitchem, Dirk Spitzer, Peter Goedegebuure, Robert H. Mach, William G. Hawkins
Open Access Publications
No abstract provided.
No Dramatic Age-Related Loss Of Hair Cells And Spiral Ganglion Neurons In Bcl-2 Over-Expression Mice Or Bax Null Mice, Haiyan Shen, Jonathan I. Matsui, Debin Lei, Lirong Han, Kevin K. Ohlemiller, Jianxin Bao
No Dramatic Age-Related Loss Of Hair Cells And Spiral Ganglion Neurons In Bcl-2 Over-Expression Mice Or Bax Null Mice, Haiyan Shen, Jonathan I. Matsui, Debin Lei, Lirong Han, Kevin K. Ohlemiller, Jianxin Bao
Open Access Publications
No abstract provided.
Analysis Of Dna Double-Strand Break Response And Chromatin Structure In Mitosis Using Laser Microirradiation, Veronica Gomez-Godinez, Tao Wu, Adria J. Sherman, Christopher S. Lee, Lih-Huei Liaw, You Zhongsheng, Kyoko Yokomori, Michael W. Berns
Analysis Of Dna Double-Strand Break Response And Chromatin Structure In Mitosis Using Laser Microirradiation, Veronica Gomez-Godinez, Tao Wu, Adria J. Sherman, Christopher S. Lee, Lih-Huei Liaw, You Zhongsheng, Kyoko Yokomori, Michael W. Berns
Open Access Publications
No abstract provided.
A Practical, Bioinformatic Workflow System For Large Data Sets Generated By Next-Generation Sequencing, Cinzia Cantacessi, Aaron R. Jex, Neil D. Young, Bronwyn E. Campbell, Anja Joachim, Matthew J. Nolan, Sahar Abubucker, Paul W. Sternberg, Shoba Ranganathan, Makedonka Mitreva, Robin B. Gasser
A Practical, Bioinformatic Workflow System For Large Data Sets Generated By Next-Generation Sequencing, Cinzia Cantacessi, Aaron R. Jex, Neil D. Young, Bronwyn E. Campbell, Anja Joachim, Matthew J. Nolan, Sahar Abubucker, Paul W. Sternberg, Shoba Ranganathan, Makedonka Mitreva, Robin B. Gasser
Open Access Publications
No abstract provided.
Computational Reprogramming Of Homing Endonuclease Specificity At Multiple Adjacent Base Pairs, Justin Ashworth, Gregory K. Taylor, James J. Havranek, S. A. Quadri, Barry L. Stoddard, David Baker
Computational Reprogramming Of Homing Endonuclease Specificity At Multiple Adjacent Base Pairs, Justin Ashworth, Gregory K. Taylor, James J. Havranek, S. A. Quadri, Barry L. Stoddard, David Baker
Open Access Publications
No abstract provided.
Snp-Snp Interactions Dominate The Genetic Architecture Of Candidate Genes Associated With Left Ventricular Mass In African-Americans Of The Genoa Study, Kristin J. Meyers, Jian Chu, Thomas H. Mosley, Sharon Lr Kardia
Snp-Snp Interactions Dominate The Genetic Architecture Of Candidate Genes Associated With Left Ventricular Mass In African-Americans Of The Genoa Study, Kristin J. Meyers, Jian Chu, Thomas H. Mosley, Sharon Lr Kardia
Open Access Publications
No abstract provided.
Modeling Complex Genetic And Environmental Influences On Comorbid Bipolar Disorder With Tobacco Use Disorder, Richard C. Mceachin, Nancy L. Saccone, Scott F. Saccone, Yelena D. Kleyman-Smith, Tiara Kar, Rajesh K. Kare, Alex S. Ade, Maureen A. Sartor, James D. Cavalcoli, Melvin G. Mcinnis
Modeling Complex Genetic And Environmental Influences On Comorbid Bipolar Disorder With Tobacco Use Disorder, Richard C. Mceachin, Nancy L. Saccone, Scott F. Saccone, Yelena D. Kleyman-Smith, Tiara Kar, Rajesh K. Kare, Alex S. Ade, Maureen A. Sartor, James D. Cavalcoli, Melvin G. Mcinnis
Open Access Publications
No abstract provided.
Deep Sequencing Of Small Rna Libraries Reveals Dynamic Regulation Of Conserved And Novel Micrornas And Microrna-Stars During Silkworm Development, Guru Jagadeeswaran, Yun Zheng, Niranji Sumathipala, Haobo Jiang, Estela L. Arrese, Jose L. Soulages, Weixiong Zhang, Ramanjulu Sunkar
Deep Sequencing Of Small Rna Libraries Reveals Dynamic Regulation Of Conserved And Novel Micrornas And Microrna-Stars During Silkworm Development, Guru Jagadeeswaran, Yun Zheng, Niranji Sumathipala, Haobo Jiang, Estela L. Arrese, Jose L. Soulages, Weixiong Zhang, Ramanjulu Sunkar
Open Access Publications
No abstract provided.
Candidate Genes For Alcohol Preference Identified By Expression Profiling In Alcohol-Preferring And -Nonpreferring Reciprocal Congenic Rats, Tiebing Liang, Mark W. Kimpel, Jeanette N. Mcclintick, Ashley R. Skillman, Kevin Mccall, Howard J. Edenberg, Lucinda G. Carr
Candidate Genes For Alcohol Preference Identified By Expression Profiling In Alcohol-Preferring And -Nonpreferring Reciprocal Congenic Rats, Tiebing Liang, Mark W. Kimpel, Jeanette N. Mcclintick, Ashley R. Skillman, Kevin Mccall, Howard J. Edenberg, Lucinda G. Carr
Open Access Publications
No abstract provided.
Analysis Of Alzheimer’S Disease Severity Across Brain Regions By Topological Analysis Of Gene Co-Expression Networks, Monika Ray, Weixiong Zhang
Analysis Of Alzheimer’S Disease Severity Across Brain Regions By Topological Analysis Of Gene Co-Expression Networks, Monika Ray, Weixiong Zhang
Open Access Publications
No abstract provided.
Multiple Distinct Small Rnas Originate From The Same Microrna Precursors, Weixiong Zhang, Shang Gao, Xuefeng Zhou, Jing Xia, Padmanabhan Chellappan, Xiang Zhou, Xiaoming Zhang, Hailing Jin
Multiple Distinct Small Rnas Originate From The Same Microrna Precursors, Weixiong Zhang, Shang Gao, Xuefeng Zhou, Jing Xia, Padmanabhan Chellappan, Xiang Zhou, Xiaoming Zhang, Hailing Jin
Open Access Publications
No abstract provided.
Encode Whole-Genome Data In The Ucsc Genome Browser, Kate R. Rosenbloom, Ting Wang, Et Al
Encode Whole-Genome Data In The Ucsc Genome Browser, Kate R. Rosenbloom, Ting Wang, Et Al
Open Access Publications
No abstract provided.
Spot: A Web-Based Tool For Using Biological Databases To Prioritize Snps After A Genome-Wide Association Study, Scott F. Saccone, Raphael Bolze, Prasanth Thomas, Jiaxi Quan, Gaurang Mehta, Ewa Deelman, Jay A. Tischfield, John P. Rice
Spot: A Web-Based Tool For Using Biological Databases To Prioritize Snps After A Genome-Wide Association Study, Scott F. Saccone, Raphael Bolze, Prasanth Thomas, Jiaxi Quan, Gaurang Mehta, Ewa Deelman, Jay A. Tischfield, John P. Rice
Open Access Publications
No abstract provided.
Type I Ifn Enhances Follicular B Cell Contribution To The T Cell-Independent Antibody Response, Cristina L. Swanson, Timothy J. Wilson, Pamela Strauch, Marco Colonna, Roberta Pelanda, Raul M. Torres
Type I Ifn Enhances Follicular B Cell Contribution To The T Cell-Independent Antibody Response, Cristina L. Swanson, Timothy J. Wilson, Pamela Strauch, Marco Colonna, Roberta Pelanda, Raul M. Torres
Open Access Publications
Humoral immunity to viruses and encapsulated bacteria is comprised of T cell-independent type 2 (TI-2) antibody responses that are characterized by rapid antibody production by marginal zone and B1 B cells. We demonstrate that toll-like receptor (TLR) ligands influence the TI-2 antibody response not only by enhancing the overall magnitude but also by skewing this response to one that is dominated by IgG isotypes. Importantly, TLR ligands facilitate this response by inducing type I interferon (IFN), which in turn elicits rapid and significant amounts of antigen-specific IgG2c predominantly from FO (follicular) B cells. Furthermore, we show that although the IgG2c …
Fibroblast Growth Factor Receptors 1 And 2 In Keratinocytes Control The Epidermal Barrier And Cutaneous Homeostasis, Jingxuan Yang, Michael Meyer, Anna-Katharina Müller, Friederike Böhm, Richard Grose, Tina Dauwalder, Francois Verrey, Manfred Kopf, Juha Partanen, Wilhelm Bloch, David M. Ornitz, Sabine Werner
Fibroblast Growth Factor Receptors 1 And 2 In Keratinocytes Control The Epidermal Barrier And Cutaneous Homeostasis, Jingxuan Yang, Michael Meyer, Anna-Katharina Müller, Friederike Böhm, Richard Grose, Tina Dauwalder, Francois Verrey, Manfred Kopf, Juha Partanen, Wilhelm Bloch, David M. Ornitz, Sabine Werner
Open Access Publications
Fibroblast growth factors (FGFs) are master regulators of organogenesis and tissue homeostasis. In this study, we used different combinations of FGF receptor (FGFR)-deficient mice to unravel their functions in the skin. Loss of the IIIb splice variants of FGFR1 and FGFR2 in keratinocytes caused progressive loss of skin appendages, cutaneous inflammation, keratinocyte hyperproliferation, and acanthosis. We identified loss of FGF-induced expression of tight junction components with subsequent deficits in epidermal barrier function as the mechanism underlying the progressive inflammatory skin disease. The defective barrier causes activation of keratinocytes and epidermal gammadelta T cells, which produce interleukin-1 family member 8 and …
Dynamic Modulation Of Local Population Activity By Rhythm Phase In Human Occipital Cortex During A Visual Search Task, Kai J. Miller, Dora Hermes, Christopher J. Honey, Mohit Sharma, Rajesh P.N. Rao, Marcel Den Nijs, Eberhard E. Fetz, Terrence J. Sejnowski, Adam O. Hebb, Jeffrey G. Ojemann, Scott Makeig, Eric C. Leuthardt
Dynamic Modulation Of Local Population Activity By Rhythm Phase In Human Occipital Cortex During A Visual Search Task, Kai J. Miller, Dora Hermes, Christopher J. Honey, Mohit Sharma, Rajesh P.N. Rao, Marcel Den Nijs, Eberhard E. Fetz, Terrence J. Sejnowski, Adam O. Hebb, Jeffrey G. Ojemann, Scott Makeig, Eric C. Leuthardt
Open Access Publications
No abstract provided.
Preventing Preterm Birth: The Past Limitations And New Potential Of Animal Models, Christine K. Ratajczak, Justin C. Fay, Louis J. Muglia
Preventing Preterm Birth: The Past Limitations And New Potential Of Animal Models, Christine K. Ratajczak, Justin C. Fay, Louis J. Muglia
Open Access Publications
No abstract provided.
Wolfram Syndrome 1 Gene Negatively Regulates Er Stress Signaling In Rodent And Human Cells, Sonya G. Fonseca, Shinsuke Ishigaki, Christine M. Oslowski, Simin Lu, Kathryn L. Lipson, Rajarshi Ghosh, Emiko Hayashi, Hisamitsu Ishihara, Yoshitomo Oka, M. Alan Permutt, Fumihiko Urano
Wolfram Syndrome 1 Gene Negatively Regulates Er Stress Signaling In Rodent And Human Cells, Sonya G. Fonseca, Shinsuke Ishigaki, Christine M. Oslowski, Simin Lu, Kathryn L. Lipson, Rajarshi Ghosh, Emiko Hayashi, Hisamitsu Ishihara, Yoshitomo Oka, M. Alan Permutt, Fumihiko Urano
Open Access Publications
No abstract provided.
Cardiac Signaling Genes Exhibit Unexpected Sequence Diversity In Sporadic Cardiomyopathy, Revealing Hspb7 Polymorphisms Associated With Disease, Scot J. Matkovich, Derek J. Van Booven, Anna Hindes, Min Young Kang, Todd E. Druley, Francesco L.M. Vallania, Robi D. Mitra, Muredach P. Reilly, Thomas P. Cappola, Gerald W. Dorn Ii
Cardiac Signaling Genes Exhibit Unexpected Sequence Diversity In Sporadic Cardiomyopathy, Revealing Hspb7 Polymorphisms Associated With Disease, Scot J. Matkovich, Derek J. Van Booven, Anna Hindes, Min Young Kang, Todd E. Druley, Francesco L.M. Vallania, Robi D. Mitra, Muredach P. Reilly, Thomas P. Cappola, Gerald W. Dorn Ii
Open Access Publications
No abstract provided.
Epimorphin Deletion Protects Mice From Inflammation-Induced Colon Carcinogenesis And Alters Stem Cell Niche Myofibroblast Secretion, Anisa Shaker, Elzbieta A. Swietlicki, Lihua Wang, Shujun Jiang, Birce Onal, Shashi Bala, Katherine Deschryver, Rodney Newberry, Marc S. Levin, Deborah C. Rubin
Epimorphin Deletion Protects Mice From Inflammation-Induced Colon Carcinogenesis And Alters Stem Cell Niche Myofibroblast Secretion, Anisa Shaker, Elzbieta A. Swietlicki, Lihua Wang, Shujun Jiang, Birce Onal, Shashi Bala, Katherine Deschryver, Rodney Newberry, Marc S. Levin, Deborah C. Rubin
Open Access Publications
No abstract provided.
Autophagy Influences Glomerular Disease Susceptibility And Maintains Podocyte Homeostasis In Aging Mice, Björn Hartleben, Markus Gödel, Catherine Meyer-Schwesinger, Shuya Liu, Theresa Ulrich, Sven Köbler, Thorsten Wiech, Florian Grahammer, Andrey S. Shaw, Noburu Mizushima, Dontscho Kerjaschki, Hermann Pavenstadt, Clemens D. Cohen, Maja T. Lindenmeyer, Sebastian J. Arnold, Et Al
Autophagy Influences Glomerular Disease Susceptibility And Maintains Podocyte Homeostasis In Aging Mice, Björn Hartleben, Markus Gödel, Catherine Meyer-Schwesinger, Shuya Liu, Theresa Ulrich, Sven Köbler, Thorsten Wiech, Florian Grahammer, Andrey S. Shaw, Noburu Mizushima, Dontscho Kerjaschki, Hermann Pavenstadt, Clemens D. Cohen, Maja T. Lindenmeyer, Sebastian J. Arnold, Et Al
Open Access Publications
No abstract provided.
Organotypic Specificity Of Key Ret Adaptor-Docking Sites In The Pathogenesis Of Neurocristopathies And Renal Malformations In Mice, Sanjay Jain, Amanda Knoten, Masato Hoshi, Hongtao Wang, Bhupinder Vohra, Robert O. Heuckeroth, Jeffrey Milbrandt
Organotypic Specificity Of Key Ret Adaptor-Docking Sites In The Pathogenesis Of Neurocristopathies And Renal Malformations In Mice, Sanjay Jain, Amanda Knoten, Masato Hoshi, Hongtao Wang, Bhupinder Vohra, Robert O. Heuckeroth, Jeffrey Milbrandt
Open Access Publications
No abstract provided.
Loss Of Nix In Pdx1-Deficient Mice Prevents Apoptotic And Necrotic Β Cell Death And Diabetes, Kei Fujimoto, Eric L. Ford, Hung Tran, Burton M. Wice, Seth D. Crosby, Gerald W. Dorn Ii, Kenneth S. Polonsky
Loss Of Nix In Pdx1-Deficient Mice Prevents Apoptotic And Necrotic Β Cell Death And Diabetes, Kei Fujimoto, Eric L. Ford, Hung Tran, Burton M. Wice, Seth D. Crosby, Gerald W. Dorn Ii, Kenneth S. Polonsky
Open Access Publications
No abstract provided.
Primary Deficiency Of Microsomal Triglyceride Transfer Protein In Human Abetalipoproteinemia Is Associated With Loss Of Cd1 Function, Susan M. Kennedy, Nicholas O. Davidson, Sebastian Zeissig, Stephanie K. Dougan, Duarte C. Barral, Yvonne Junker, Zhangguo Chen, Arthur Kaser, Madelyn Ho, Hannah Mandel, Adam Mcintyre, Gavin F. Painter, Natacha Veerapen, Gurdyal S. Besra, Et Al
Primary Deficiency Of Microsomal Triglyceride Transfer Protein In Human Abetalipoproteinemia Is Associated With Loss Of Cd1 Function, Susan M. Kennedy, Nicholas O. Davidson, Sebastian Zeissig, Stephanie K. Dougan, Duarte C. Barral, Yvonne Junker, Zhangguo Chen, Arthur Kaser, Madelyn Ho, Hannah Mandel, Adam Mcintyre, Gavin F. Painter, Natacha Veerapen, Gurdyal S. Besra, Et Al
Open Access Publications
No abstract provided.
Cxcr2 And Cxcr4 Antagonistically Regulate Neutrophil Trafficking From Murine Bone Marrow, Kyle J. Eash, Adam M. Greenbaum, Priya K. Gopalan, Daniel C. Link
Cxcr2 And Cxcr4 Antagonistically Regulate Neutrophil Trafficking From Murine Bone Marrow, Kyle J. Eash, Adam M. Greenbaum, Priya K. Gopalan, Daniel C. Link
Open Access Publications
No abstract provided.
Cxcl12 Inhibits Expression Of The Nmda Receptor's Nr2b Subunit Through A Histone Deacetylase-Dependent Pathway Contributing To Neuronal Survival, J. Nicolai, S. Burbassi, J. Rubin, O. Meucci
Cxcl12 Inhibits Expression Of The Nmda Receptor's Nr2b Subunit Through A Histone Deacetylase-Dependent Pathway Contributing To Neuronal Survival, J. Nicolai, S. Burbassi, J. Rubin, O. Meucci
Open Access Publications
No abstract provided.
A New Statistic To Evaluate Imputation Reliability, Peng Lin, Sarah M. Hartz, Zhehao Zhang, Scott F. Saccone, Jia Wang, Jay A. Tischfield, Howard J. Edenberg, John R. Kramer, Alison M. Goate, Laura J. Bierut, John P. Rice, Coga Collaborators Cogend Collaborators
A New Statistic To Evaluate Imputation Reliability, Peng Lin, Sarah M. Hartz, Zhehao Zhang, Scott F. Saccone, Jia Wang, Jay A. Tischfield, Howard J. Edenberg, John R. Kramer, Alison M. Goate, Laura J. Bierut, John P. Rice, Coga Collaborators Cogend Collaborators
Open Access Publications
No abstract provided.