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Distinct Time-Resolved Roles For Two Catabolite-Sensing Pathways During Streptococcus Pyogenes Infection, Colin C. Kietzman, Michael G. Caparon Jan 2011

Distinct Time-Resolved Roles For Two Catabolite-Sensing Pathways During Streptococcus Pyogenes Infection, Colin C. Kietzman, Michael G. Caparon

Open Access Publications

No abstract provided.


Role Of Fatty Acid Transporters In Epidermis: Implications For Health And Disease, Denis Khnykin, Jeffrey H. Miner, Frode Jahnsen Jan 2011

Role Of Fatty Acid Transporters In Epidermis: Implications For Health And Disease, Denis Khnykin, Jeffrey H. Miner, Frode Jahnsen

Open Access Publications

No abstract provided.


The Diverse Functions Of Short-Term Plasticity Components In Synaptic Computations, Pan-Yue Deng, Vitaly A. Klyachko Jan 2011

The Diverse Functions Of Short-Term Plasticity Components In Synaptic Computations, Pan-Yue Deng, Vitaly A. Klyachko

Open Access Publications

No abstract provided.


Inhibition Of Indoleamine 2,3-Dioxygenase Activity By Levo-1-Methyl Tryptophan Blocks Gamma Interferon-Induced Chlamydia Trachomatis Persistence In Human Epithelial Cells, Joyce A. Ibana, Robert J. Belland, Arnold H. Zea, Danny J. Schust, Takeshi Nagamatsu, Yasser M. Abdelrahman, David J. Tate, Wandy L. Beatty, Ashok A. Aiyar, Alison J. Quayle Jan 2011

Inhibition Of Indoleamine 2,3-Dioxygenase Activity By Levo-1-Methyl Tryptophan Blocks Gamma Interferon-Induced Chlamydia Trachomatis Persistence In Human Epithelial Cells, Joyce A. Ibana, Robert J. Belland, Arnold H. Zea, Danny J. Schust, Takeshi Nagamatsu, Yasser M. Abdelrahman, David J. Tate, Wandy L. Beatty, Ashok A. Aiyar, Alison J. Quayle

Open Access Publications

No abstract provided.


Structural And Functional Interactions Between The Cholera Toxin A1 Subunit And Erdj3/Hedj, A Chaperone Of The Endoplasmic Reticulum, Shane Massey, Helen Burress, Michael Taylor, Kathleen N. Nemec, Supriyo Ray, David B. Haslam, Ken Teter Jan 2011

Structural And Functional Interactions Between The Cholera Toxin A1 Subunit And Erdj3/Hedj, A Chaperone Of The Endoplasmic Reticulum, Shane Massey, Helen Burress, Michael Taylor, Kathleen N. Nemec, Supriyo Ray, David B. Haslam, Ken Teter

Open Access Publications

No abstract provided.


Population Dynamics And Niche Distribution Of Uropathogenic Escherichia Coli During Acute And Chronic Urinary Tract Infection, Drew J. Schwartz, Swaine L. Chen, Scott J. Hultgren, Patrick C. Seed Jan 2011

Population Dynamics And Niche Distribution Of Uropathogenic Escherichia Coli During Acute And Chronic Urinary Tract Infection, Drew J. Schwartz, Swaine L. Chen, Scott J. Hultgren, Patrick C. Seed

Open Access Publications

No abstract provided.


Immune Activation And Suppression By Group B Streptococcus In A Murine Model Of Urinary Tract Infection, Kimberly A. Kline, Drew J. Schwartz, Warren G. Lewis, Scott J. Hultgren, Amanda L. Lewis Jan 2011

Immune Activation And Suppression By Group B Streptococcus In A Murine Model Of Urinary Tract Infection, Kimberly A. Kline, Drew J. Schwartz, Warren G. Lewis, Scott J. Hultgren, Amanda L. Lewis

Open Access Publications

No abstract provided.


Differential Microbicidal Effects Of Human Histone Proteins H2a And H2b On Leishmania Promastigotes And Amastigotes, Yingwei Wang, Yang Chen, Lijun Xin, Stephen M. Beverley, Eric D. Carlsen, Vsevolod Popov, Kwang-Poo Chang, Ming Wang, Lynn Soong Jan 2011

Differential Microbicidal Effects Of Human Histone Proteins H2a And H2b On Leishmania Promastigotes And Amastigotes, Yingwei Wang, Yang Chen, Lijun Xin, Stephen M. Beverley, Eric D. Carlsen, Vsevolod Popov, Kwang-Poo Chang, Ming Wang, Lynn Soong

Open Access Publications

No abstract provided.


Implications Of The Prion-Related Q/N Domains In Tdp-43 And Fus, Maria Udan, Robert H. Baloh Jan 2011

Implications Of The Prion-Related Q/N Domains In Tdp-43 And Fus, Maria Udan, Robert H. Baloh

Open Access Publications

No abstract provided.


Register Shifting Of An Insulin Peptide-Mhc Complex Allows Diabetogenic T Cells To Escape Thymic Deletion, James F. Mohan, Shirley J. Petzold, Emil R. Unanue Jan 2011

Register Shifting Of An Insulin Peptide-Mhc Complex Allows Diabetogenic T Cells To Escape Thymic Deletion, James F. Mohan, Shirley J. Petzold, Emil R. Unanue

Open Access Publications

In nonobese diabetic (NOD) mice, two sets of autoreactive CD4(+) T cells recognize the B:9-23 segment of the insulin B chain. One set, type A, recognizes insulin presented by antigen-presenting cells (APCs). These T cells are highly deleted in the thymus. The second set, type B, does not recognize insulin protein but reacts with soluble B chain peptide. This set is not deleted in the thymus but is activated in the islets of Langerhans. In this study, we examine the specificity of these two types of T cells. The protein-reactive set recognizes the stretch of residues 13-21 of the insulin …


Innate And Cytokine-Driven Signals, Rather Than Microbial Antigens, Dominate In Natural Killer T Cell Activation During Microbial Infection, Manfred Brigl, Raju V.V. Tatituri, Gerald F.M. Watts, Veemal Bhowruth, Elizabeth A. Leadbetter, Nathaniel Barton, Nadia R. Cohen, Fong-Fu Hsu, Gurdyal S. Besra, Michael B. Brenner Jan 2011

Innate And Cytokine-Driven Signals, Rather Than Microbial Antigens, Dominate In Natural Killer T Cell Activation During Microbial Infection, Manfred Brigl, Raju V.V. Tatituri, Gerald F.M. Watts, Veemal Bhowruth, Elizabeth A. Leadbetter, Nathaniel Barton, Nadia R. Cohen, Fong-Fu Hsu, Gurdyal S. Besra, Michael B. Brenner

Open Access Publications

Invariant natural killer T cells (iNKT cells) are critical for host defense against a variety of microbial pathogens. However, the central question of how iNKT cells are activated by microbes has not been fully explained. The example of adaptive MHC-restricted T cells, studies using synthetic pharmacological α-galactosylceramides, and the recent discovery of microbial iNKT cell ligands have all suggested that recognition of foreign lipid antigens is the main driver for iNKT cell activation during infection. However, when we compared the role of microbial antigens versus innate cytokine-driven mechanisms, we found that iNKT cell interferon-γ production after in vitro stimulation or …


Cxcr7 Antagonism Prevents Axonal Injury During Experimental Autoimmune Encephalomyelitis As Revealed By In Vivo Axial Diffusivity, Lillian Cruz-Orengo, Ying-Jr Chen, Joong Hee Kim, Denise Dorsey, Sheng-Kwei Song, Robyn S. Klein Jan 2011

Cxcr7 Antagonism Prevents Axonal Injury During Experimental Autoimmune Encephalomyelitis As Revealed By In Vivo Axial Diffusivity, Lillian Cruz-Orengo, Ying-Jr Chen, Joong Hee Kim, Denise Dorsey, Sheng-Kwei Song, Robyn S. Klein

Open Access Publications

No abstract provided.


Pregnancy In Multiple System Atrophy: A Case Report, Lirong Zhu, Nigel J. Cairns, Samer D. Tabbal, Brad A. Racette Jan 2011

Pregnancy In Multiple System Atrophy: A Case Report, Lirong Zhu, Nigel J. Cairns, Samer D. Tabbal, Brad A. Racette

Open Access Publications

No abstract provided.


Engraftment Of Insulin-Producing Cells From Porcine Islets In Non-Immune-Suppressed Rats Or Nonhuman Primates Transplanted Previously With Embryonic Pig Pancreas, Marc R. Hammerman Jan 2011

Engraftment Of Insulin-Producing Cells From Porcine Islets In Non-Immune-Suppressed Rats Or Nonhuman Primates Transplanted Previously With Embryonic Pig Pancreas, Marc R. Hammerman

Open Access Publications

No abstract provided.


Statistical Analysis And Interpretation Of Prenatal Diagnostic Imaging Studies, Part 1: Evaluating The Efficiency Of Screening And Diagnostic Tests, Katherine R. Goetzinger, Anthony O. Odibo Jan 2011

Statistical Analysis And Interpretation Of Prenatal Diagnostic Imaging Studies, Part 1: Evaluating The Efficiency Of Screening And Diagnostic Tests, Katherine R. Goetzinger, Anthony O. Odibo

Open Access Publications

No abstract provided.


The Genetic Association Between Personality And Major Depression Or Bipolar Disorder. A Polygenic Score Analysis Using Genome-Wide Association Data, P. A. F. Madden, A. C. Heath, M. L. Pergadia, A. Agrawal, P. Lin, R. A. Grucza, L. J. Bierut, Et Al Jan 2011

The Genetic Association Between Personality And Major Depression Or Bipolar Disorder. A Polygenic Score Analysis Using Genome-Wide Association Data, P. A. F. Madden, A. C. Heath, M. L. Pergadia, A. Agrawal, P. Lin, R. A. Grucza, L. J. Bierut, Et Al

Open Access Publications

No abstract provided.


A Rapid Communication From The Aapm Task Group 201: Recommendations For The Qa Of External Beam Radiotherapy Data Transfer. Aapm Tg 201: Quality Assurance Of External Beam Radiotherapy Data Transfer, R. Alfredo Siochi, Peter Balter, Charles D. Bloch, Lakshmi Santanam, Kurt Blodgett, Bruce H. Curran, Martijn Engelsman, Wenzheng Feng, Jim Mechalakos, Dan Pavord, Tom Simon, Steven Sutlief, X. Ronald Zhu Jan 2011

A Rapid Communication From The Aapm Task Group 201: Recommendations For The Qa Of External Beam Radiotherapy Data Transfer. Aapm Tg 201: Quality Assurance Of External Beam Radiotherapy Data Transfer, R. Alfredo Siochi, Peter Balter, Charles D. Bloch, Lakshmi Santanam, Kurt Blodgett, Bruce H. Curran, Martijn Engelsman, Wenzheng Feng, Jim Mechalakos, Dan Pavord, Tom Simon, Steven Sutlief, X. Ronald Zhu

Open Access Publications

No abstract provided.


The Mammalian Cone Visual Cycle Promotes Rapid M/L-Cone Pigment Regeneration Independently Of The Interphotoreceptor Retinoid-Binding Protein, Alexander V. Kolesnikov, Peter H. Tang, Ryan O. Parker, Rosalie K. Crouch, Vladimir J. Kefalov Jan 2011

The Mammalian Cone Visual Cycle Promotes Rapid M/L-Cone Pigment Regeneration Independently Of The Interphotoreceptor Retinoid-Binding Protein, Alexander V. Kolesnikov, Peter H. Tang, Ryan O. Parker, Rosalie K. Crouch, Vladimir J. Kefalov

Open Access Publications

No abstract provided.


Implementation Of Whole Slide Imaging In Surgical Pathology: A Value Added Approach, Mike Isaacs, Jochen K. Lennerz, Stacey Yates, Walter Clermont, Joan Rossi, John D. Pfeifer Jan 2011

Implementation Of Whole Slide Imaging In Surgical Pathology: A Value Added Approach, Mike Isaacs, Jochen K. Lennerz, Stacey Yates, Walter Clermont, Joan Rossi, John D. Pfeifer

Open Access Publications

No abstract provided.


Opposing Synaptic Regulation Of Amyloid-Β Metabolism By Nmda Receptors In Vivo, Deborah K. Verges, Jessica L. Restivo, Whitney D. Goebel, David M. Holtzman, John R. Cirrito Jan 2011

Opposing Synaptic Regulation Of Amyloid-Β Metabolism By Nmda Receptors In Vivo, Deborah K. Verges, Jessica L. Restivo, Whitney D. Goebel, David M. Holtzman, John R. Cirrito

Open Access Publications

No abstract provided.


Lung Transplantation For Pulmonary Fibrosis In Dyskeratosis Congenita: Case Report And Systematic Literature Review, Neelam Giri, Rees Lee, Albert Faro, Charles B. Huddleston, Frances V. White, Blanche P. Alter, Sharon A. Savage Jan 2011

Lung Transplantation For Pulmonary Fibrosis In Dyskeratosis Congenita: Case Report And Systematic Literature Review, Neelam Giri, Rees Lee, Albert Faro, Charles B. Huddleston, Frances V. White, Blanche P. Alter, Sharon A. Savage

Open Access Publications

No abstract provided.


Evolving Diagnostic And Treatment Strategies For Pancreatic Neuroendocrine Tumors, Matthew H. Kulke, Johanna Bendell, Larry Kvols, Joel Picus, Rodney Pommier, James Yao Jan 2011

Evolving Diagnostic And Treatment Strategies For Pancreatic Neuroendocrine Tumors, Matthew H. Kulke, Johanna Bendell, Larry Kvols, Joel Picus, Rodney Pommier, James Yao

Open Access Publications

No abstract provided.


Correlation Of Cag Repeat Length Between The Maternal And Paternal Allele Of The Huntingtin Gene: Evidence For Assortative Mating, Peg Nopoulos, Eric A. Epping, Tom Wassink, Bradley L. Schlaggar, Joel Perlmutter Jan 2011

Correlation Of Cag Repeat Length Between The Maternal And Paternal Allele Of The Huntingtin Gene: Evidence For Assortative Mating, Peg Nopoulos, Eric A. Epping, Tom Wassink, Bradley L. Schlaggar, Joel Perlmutter

Open Access Publications

No abstract provided.


Genetic Incorporation Of Human Metallothionein Into The Adenovirus Protein Ix For Non-Invasive Spect Imaging, J. Michael Mathis, Shilpa Bhatia, Alok Khandelwal, Imre Kovesdi, Stephen J. Lokitz, Yoshi Odaka, Amol M. Takalkar, Tracee Terry, David T. Curiel Jan 2011

Genetic Incorporation Of Human Metallothionein Into The Adenovirus Protein Ix For Non-Invasive Spect Imaging, J. Michael Mathis, Shilpa Bhatia, Alok Khandelwal, Imre Kovesdi, Stephen J. Lokitz, Yoshi Odaka, Amol M. Takalkar, Tracee Terry, David T. Curiel

Open Access Publications

No abstract provided.


Actin Depolymerizing Factor Controls Actin Turnover And Gliding Motility In Toxoplasma Gondii, Simren Mehta, L. David Sibley Jan 2011

Actin Depolymerizing Factor Controls Actin Turnover And Gliding Motility In Toxoplasma Gondii, Simren Mehta, L. David Sibley

Open Access Publications

No abstract provided.


Mapping Human Cortical Areas In Vivo Based On Myelin Content As Revealed By T1- And T2-Weighted Mri, Matthew F. Glasser, David C. Van Essen Jan 2011

Mapping Human Cortical Areas In Vivo Based On Myelin Content As Revealed By T1- And T2-Weighted Mri, Matthew F. Glasser, David C. Van Essen

Open Access Publications

No abstract provided.


Cerebral Infarction Following A Seizure In A Patient With Subarachnoid Hemorrhage Complicated By Delayed Cerebral Ischemia, Tomoko Rie Sampson, Rajat Dhar, Gregory J. Zipfel Jan 2011

Cerebral Infarction Following A Seizure In A Patient With Subarachnoid Hemorrhage Complicated By Delayed Cerebral Ischemia, Tomoko Rie Sampson, Rajat Dhar, Gregory J. Zipfel

Open Access Publications

No abstract provided.


New Tools And Methods For Direct Programmatic Access To The Dbsnp Relational Database, Scott F. Saccone, Jiaxi Quan, Gaurang Mehta, Raphael Bolze, Prasanth Thomas, Ewa Deelman, Jay A. Tischfield, John P. Rice Jan 2011

New Tools And Methods For Direct Programmatic Access To The Dbsnp Relational Database, Scott F. Saccone, Jiaxi Quan, Gaurang Mehta, Raphael Bolze, Prasanth Thomas, Ewa Deelman, Jay A. Tischfield, John P. Rice

Open Access Publications

No abstract provided.


Genome-Wide Joint Snp And Cnv Analysis Of Aortic Root Diameter In African Americans: The Hypergen Study, Nathan E. Wineinger, Amit Patki, Kristin J. Meyers, Ulrich Broeckel, Charles C. Gu, Dc Rao, Richard B. Devereux, Donna K. Arnett, Herman K. Tiwari Jan 2011

Genome-Wide Joint Snp And Cnv Analysis Of Aortic Root Diameter In African Americans: The Hypergen Study, Nathan E. Wineinger, Amit Patki, Kristin J. Meyers, Ulrich Broeckel, Charles C. Gu, Dc Rao, Richard B. Devereux, Donna K. Arnett, Herman K. Tiwari

Open Access Publications

No abstract provided.


Batf3-Dependent Cd11b Peripheral Dendritic Cells Are Gm-Csf-Independent And Are Not Required For Th Cell Priming After Subcutaneous Immunization, Brian T. Edelson, Tara R. Bradstreet, Wumesh Kc, Kai Hildner, Jeremy W. Herzog, Julia Sim, John H. Russell, Theresa L. Murphy, Emil R. Unanue, Kenneth M. Murphy Jan 2011

Batf3-Dependent Cd11b Peripheral Dendritic Cells Are Gm-Csf-Independent And Are Not Required For Th Cell Priming After Subcutaneous Immunization, Brian T. Edelson, Tara R. Bradstreet, Wumesh Kc, Kai Hildner, Jeremy W. Herzog, Julia Sim, John H. Russell, Theresa L. Murphy, Emil R. Unanue, Kenneth M. Murphy

Open Access Publications

No abstract provided.