Digital Commons Network^™

A Clinical Trial Using Methylation Age To Evaluate Current Antiaging Practices, Josh Mitteldorf

Open Access Publications

No abstract provided.

Cdk1 And Cdk2 Regulate Nicd1 Turnover And The Periodicity Of The Segmentation Clock, Francesca Anna Carrieri, Philip J. Murray, Dimitrinka Ditsova, Margaret Ashley Ferris, Paul Davies, Jacqueline Kim Dale

Open Access Publications

No abstract provided.

A Longitudinal Study Of Neurocognition And Behavior In Patients With Hurler-Scheie Syndrome Heterozygous For The L238q Mutation, Alia Ahmed, Li Ou, Kyle Rudser, Elsa Shapiro, Julie B. Eisengart, Kelly King, Agnes Chen, Patricia Dickson, Chester B. Whitley

Open Access Publications

No abstract provided.

How Effective Are Noninvasive Tests For Diagnosing Malignant Peripheral Nerve Sheath Tumors In Patients With Neurofibromatosis Type 1? Diagnosing Mpnst In Nf1 Patients, Maria Schwabe, Stanislav Spiridonov, Elizabeth L. Yanik, Jack W. Jennings, Travis Hillen, Maria Ponisio, Douglas J. Mcdonald, Farrokh Dehdashti, Cara A. Cipriano

Open Access Publications

No abstract provided.

7‑Hydroxymitragynine Is An Active Metabolite Of Mitragynine And A Key Mediator Of Its Analgesic Effects, Andrew C. Kruegel, Rajendra Uprety, Steven G. Grinnell, Cory Langreck, Elizabeth A. Pekarskaya, Valerie Le Rouzic, Michael Ansonoff, Madalee M. Gassaway, John E. Pintar, Gavril W. Pasternak, Jonathan A. Javitch, Susruta Majumdar, Dalibor Sames

Open Access Publications

No abstract provided.

Phosphorylation Of The Hcn Channel Auxiliary Subunit Trip8b Is Altered In An Animal Model Of Temporal Lobe Epilepsy And Modulates Channel Function, Kendall M. Foote, Kyle A. Lyman, Ye Han, Ioannis E. Michailidis, Robert J. Heuermann, Danielle Mandikian, James S. Trimmer, Geoffrey T. Swanson, Dane M. Chetkovich

Open Access Publications

No abstract provided.

Test–Retest Performance Of A 1-Hour Multiparametric Mr Image Acquisition Pipeline With Orthotopic Triple-Negative Breast Cancer Patient-Derived Tumor Xenografts, Xia Ge, James D. Quirk, John A. Engelbach, G. Larry Bretthorst, Shunqiang Li, Kooresh I. Shoghi, Joel R. Garbow, Joseph J.H. Ackerman

Open Access Publications

No abstract provided.

Comparative Genomic Analysis Of Six Glossina Genomes, Vectors Of African Trypanosomes, Geoffrey M. Attardo, Patrick Minx, Chad Tomlinson, Wesley C. Warren, Richard K. Wilson, Et Al

Open Access Publications

No abstract provided.

Nix-Mediated Mitophagy Promotes Effector Memory Formation In Antigen-Specific Cd8+ T Cells, Shubhranshu S. Gupta, Robert Sharp, Colby Hofferek, Le Kuai, Gerald W. Dorn Ii, Jin Wang, Min Chen

Open Access Publications

No abstract provided.

Rory Regulates The Nlrp3 Inflammasome, Cyrielle Billon, Meghan H. Murray, Amer Avdagic, Thomas P. Burris

Open Access Publications

No abstract provided.

Thiol Isomerase Erp57 Targets And Modulates The Lectin Pathway Of Complement Activation, Oskar Eriksson, Joyce Chiu, Philip J. Hogg, John P. Atkinson, M. Kathryn Liszewski, Robert Flaumenhaft, Bruce Furie

Open Access Publications

No abstract provided.

Poroid Hidradenoma Of The Scalp In An Immunosuppressed Patient, Matthew T. Grant, Michael M. Awad

Open Access Publications

No abstract provided.

A Stable Tetramer Is Not The Only Oligomeric State That Mitochondrial Single-Stranded Dna Binding Proteins Can Adopt, Saurabh P. Singh, Vandna Kukshal, Roberto Galletto

Open Access Publications

No abstract provided.

N-Acyl-O-Phosphocholineserines: Structures Of A Novel Class Of Lipids That Are Biomarkers For Niemann-Pick C1 Disease, Rohini Sidhu, Yawo Mondjinou, Mingxing Qian, Fong-Fu Hsu, Dennis J. Dietzen, Jean E. Schaffer, Daniel S. Ory, Xuntian Jiang, Et Al.

Open Access Publications

No abstract provided.

Mild Chronic Perturbation Of Inhibition Severely Alters Hippocampal Function, Min-Yu Sun, Luke Ziolkowski, Peter Lambert, Hong-Jin Shu, Micah Keiser, Nicholas Rensing, Natasha Warikoo, Monika Martinek, Carson Platnick, Ann Benz, John Bracamontes, Gustav Akk, Joe Henry Steinbach, Charles F. Zorumski, Michael Wong, Steven Mennerick

Open Access Publications

No abstract provided.

An Overview Of Mechanical Circulatory Support In Single-Ventricle Patients, Jacob R Miller, Timothy S Lancaster, Connor Callahan, Aaron M Abarbanell, Pirooz Eghtesady

Open Access Publications

The population of people with a single-ventricle is continually increasing due to improvements across the spectrum of medical care. Unfortunately, a proportion of these patients will develop heart failure. Often, for these patients, mechanical circulatory support (MCS) represents the only available treatment option. While single-ventricle patients currently represent a small proportion of the total number of patients who receive MCS, as the single-ventricle patient population increases, this number will increase as well. Outcomes for these complex single-ventricle patients who require MCS has begun to be evaluated. When considering the entire population, survival to hospital discharge is 30-50%, though this must …

Graft Immaturity And Safety Concerns In Transplanted Human Kidney Organoids, Sun Ah Nam, Kohei Uchimura, Benjamin D. Humphreys, Et Al.

Open Access Publications

No abstract provided.

Development Of A Standardized Communication Intervention Bundle For Use At A Medical Training Hospital Intensive Care Unit, Katherine Pollard, Brian Todd Wessman

Open Access Publications

No abstract provided.

Dissemination And Stakeholder Engagement Practices Among Dissemination & Implementation Scientists: Results From An Online Survey, Christopher E. Knoepke, M. Pilar Ingle, Daniel D. Matlock, Ross C. Brownson, Russell E. Glasgow

Open Access Publications

No abstract provided.

Dysregulation Of Stat3 Signaling Is Associated With Endplate-Oriented Herniations Of The Intervertebral Disc In Adgrg6 Mutant Mice, Zhaoyang Liu, Garrett W. D. Easson, Jingjing Zhao, Nadja Makki, Nadav Ahituv, Matthew J. Hilton, Simon Y. Tang, Ryan S. Gray

Open Access Publications

No abstract provided.

Multi-Ancestry Sleep-By-Snp Interaction Analysis In 126,926 Individuals Reveals Lipid Loci Stratified By Sleep Duration, Raymond Noordam, Yun Ju Sung, Karen Schwander, Lisa De Las Fuentes, Treva K. Rice, Dabeeru C. Rao, Mary Feitosa, Aldi Kraja, Mike Province, Et Al.

Open Access Publications

No abstract provided.

A Neural Network For Information Seeking, J. Kael White, Ethan S. Bromberg-Martin, Sarah R. Heilbronner, Kaining Zhang, Julia Pai, Suzanne N. Haber, Ilya E. Monosov

Open Access Publications

No abstract provided.

Comparative Analysis Of Roseoloviruses In Humans, Pigs, Mice, And Other Species, Joachim Denner, Tarin M Bigley, Tuan L Phan, Cosima Zimmermann, Xiaofeng Zhou, Benedikt B Kaufer

Open Access Publications

Viruses of the genus

End Points For Sickle Cell Disease Clinical Trials: Patient-Reported Outcomes, Pain, And The Brain, Ann T. Farrell, Allison A. King, Et Al.

Open Access Publications

No abstract provided.

A Review Of The Immunomodulating Components Of Maternal Breast Milk And Protection Against Necrotizing Enterocolitis, Lila S Nolan, Olivia B Parks, Misty Good

Open Access Publications

Breast milk contains immunomodulating components that are beneficial to newborns during maturation of their immune system. Human breast milk composition is influenced by an infant's gestational and chronological age, lactation stage, and the mother and infant's health status. Major immunologic components in human milk, such as secretory immunoglobulin A (IgA) and growth factors, have a known role in regulating gut barrier integrity and microbial colonization, which therefore protect against the development of a life-threatening gastrointestinal illness affecting newborn infants called necrotizing enterocolitis (NEC). Breast milk is a known protective factor in the prevention of NEC when compared with feeding with …

Changes In Food Cravings And Eating Behavior After A Dietary Carbohydrate Restriction Intervention Trial, Katherene O-B Anguah, Majid M Syed-Abdul, Qiong Hu, Miriam Jacome-Sosa, Colette Heimowitz, Vicki Cox, Elizabeth J Parks

Open Access Publications

Compared to low-fat diets, low-carbohydrate (CHO) diets cause weight loss (WL) over a faster time frame; however, it is unknown how changes in food cravings and eating behavior contribute to this more rapid WL in the early phases of dieting. We hypothesized that reductions in food cravings and improved eating behaviors would be evident even after a relatively short (4-week) duration of CHO-restriction, and that these changes would be associated with WL. Adult participants (

Trpv1 Activity And Substance P Release Are Required For Corneal Cold Nociception, Fengxian Li, Weishan Yang, Haowu Jiang, Changxiong Guo, Andrew J.W. Huang, Hongzhen Hu, Qin Liu

Open Access Publications

No abstract provided.

Resolution Of Secondary Hemophagocytic Lymphohistiocytosis After Treatment With The Jak1/2 Inhibitor Ruxolitinib, Scott R. Goldsmith, Sana Saif Ur Rehman, Cara L. Shirai, Kiran Vij, John F. Dipersio

Open Access Publications

No abstract provided.

Infammatory Bowel Disease-Associated Ubiquitin Ligase Rnf183 Promotes Lysosomal Degradation Of Dr5 And Trail-Induced Caspase Activation, Yan Wu, Yuka Kimura, Takumi Okamoto, Koji Matsuhisa, Rie Asada, Atsushi Saito, Fumika Sakaue, Kazunori Imaizumi, Masayuki Kaneko

Open Access Publications

No abstract provided.

Microstructural Abnormalities In Deep And Superficial White Matter In Youths With Mild Traumatic Brain Injury, Sonja Stojanovski, Arash Nazeri, Christian Lepage, Stephanie Ameis, Aristotle N Voineskos, Anne L Wheeler

Open Access Publications

BACKGROUND: Diffusion Tensor Imaging (DTI) studies of traumatic brain injury (TBI) have focused on alterations in microstructural features of deep white matter fibers (DWM), though post-mortem studies have demonstrated that injured axons are often observed at the gray-white matter interface where superficial white matter fibers (SWM) mediate local connectivity.

OBJECTIVES: To examine microstructural alterations in SWM and DWM in youths with a history of mild TBI and examine the relationship between white matter alterations and attention.

METHODS: Using DTIDWM fractional anisotropy (FA) and SWM FA in youths with mild TBI (TBI, n=63) were compared to typically developing and psychopathology matched …