Digital Commons Network^™

Clinical Outcomes With Neoadjuvant Versus Adjuvant Chemotherapy For Triple Negative Breast Cancer: A Report From The National Cancer Database, Nusayba A Bagegni, Yu Tao, Foluso O Ademuyiwa

Open Access Publications

PURPOSE: Triple negative breast cancer (TNBC) patients frequently receive neoadjuvant chemotherapy (NAC). Only 50% will achieve pathological complete response (pCR). In this retrospective study, we evaluated TNBC outcomes with NAC vs. AC.

METHODS: Patients with stages II and III TNBC treated with NAC or AC between 2010 and 2013 were identified from the National Cancer Database. Baseline characteristics were compared with χ2 and two sample t tests. Kaplan-Meier survival analyses were computed in patients treated with NAC or AC, and log-rank tests used to examine differences. Unadjusted analyses of trends in proportions over time were performed using Cochran-Armitage tests. Log-binomial …

Portable Infrared Imaging For Longitudinal Limb Volume Monitoring In Patients With Lymphatic Filariasis, Celia Zhou, Channa Yahathugoda, Lalindi De Silva, Upeksha Rathnapala, Grant Owen, Mirani Weerasooriya, Ramakrishna U Rao, Gary J Weil, Philip J Budge

Open Access Publications

BACKGROUND: The Global Programme to Eliminate Lymphatic Filariasis (LF) emphasizes hygiene, exercise, and other measures to reduce morbidity and disability related to LF. We recently reported that a portable, three-dimensional, infrared imaging system (3DIS) provides accurate limb volume measurements in patients with filarial lymphedema. To assess the practical utility of repeated 3DIS measurements for longitudinal lymphedema management, we examined intraday and day-to-day leg volume changes in adults with filarial lymphedema in southern Sri Lanka.

METHODOLOGY AND PRINCIPAL FINDINGS: We assessed 41 participants with lower extremity lymphedema (stages 1-6) in their homes in the mornings (6:00-9:00 AM) and afternoons (2:00-6:00 PM) …

Mri Quality Control For Low-Field Mr-Igrt Systems: Lessons Learned, H Michael Gach, Austen N Curcuru, Erin J Wittland, Borna Maraghechi, Bin Cai, Sasa Mutic, Olga L Green

Open Access Publications

PURPOSE: To present lessons learned from magnetic resonance imaging (MRI) quality control (QC) tests for low-field MRI-guided radiation therapy (MR-IGRT) systems.

METHODS: MRI QC programs were established for low-field MRI-

RESULTS: Image noise and artifacts were attributed to room noise sources, unsatisfactory system cabling, and broken RF receiver coils. Gantry angle-dependent magnetic field inhomogeneities were more prominent on the MRI-Linac due to the high volume of steel shielding in the gantry. B

CONCLUSIONS: There are significant technological challenges associated with implementing and maintaining MR-IGRT systems. Most of the performance issues were identified and resolved during commissioning.

Mechanism Of Microtubule Plus-End Tracking By The Plant-Specific Spr1 Protein And Its Development As A Versatile Plus-End Marker, Rachappa Balkunde, Layla Foroughi, Eric Ewan, Ryan Emenecker, Valeria Cavalli, Ram Dixit

Open Access Publications

No abstract provided.

Structural And Functional Evidence That Lipoprotein Lpqn Supports Cell Envelope Biogenesis In Mycobacterium Tuberculosis, Geoff C. Melly, Haley Stokas, Jennifer L. Dunaj, Fong Fu Hsu, Malligarjunan Rajavel, Chih-Chia Su, Edward W. Yu, Georgiana E. Purdy

Open Access Publications

No abstract provided.

A Comparison Of Resting State Functional Magnetic Resonance Imaging To Invasive Electrocortical Stimulation For Sensorimotor Mapping In Pediatric Patients, Jarod L. Roland, Carl D. Hacker, Abraham Z. Snyder, Joshua S. Shimony, John M. Zempel, David D. Limbrick, Matthew D. Smyth, Eric C. Leuthardt

Open Access Publications

No abstract provided.

Aav9-Taz Gene Replacement Ameliorates Cardiac Tmt Proteomic Profiles In A Mouse Model Of Barth Syndrome, Silveli Suzuki-Hatano, Madhurima Saha, Meghan S. Soustek, Peter B. Kang, Barry J. Byrne, W. Todd Cade, Christina A. Pacak

Open Access Publications

No abstract provided.

Neuroinflammation And Myelin Status In Alzheimer’S Disease, Parkinson’S Disease, And Normal Aging Brains: A Small Sample Study, Fei Han, Richard J. Perrin, Qing Wang, Yong Wang, Joel S. Perlmutter, John C. Morris, Tammie L. S. Benzinger, Jinbin Xu

Open Access Publications

No abstract provided.

Developing A Survey Tool To Assess Implementation Of Evidence-Based Chronic Disease Prevention In Public Health Settings Across Four Countries, Elizabeth L. Budd, Xiangji Ying, Katherine A. Stamatakis, Anna J. Deruyter, Zhaoxin Wang, Pauline Sung, Tahna Pettman, Rebecca Armstong, Rodrigo Reis, Ross C. Brownson

Open Access Publications

No abstract provided.

Evaluation Of An Enhanced Viscosity Artificial Tear For Moderate To Severe Dry Eye Disease: A Multicenter, Double-Masked, Randomized 30-Day Study, Christopher Lievens, Gregg Berdy, David Douglass, Stephen Montaquila, Hugh Lin, Peter Simmons, Cindy Carlisle-Wilcox, Joseph Vehige, Sameena Haque

Open Access Publications

No abstract provided.

Mouse Norovirus Infection Arrests Host Cell Translation Uncoupled From The Stress Granule-Pkr-Eif2Α Axis, Svenja Fritzlar, Turgut E. Aktepe, Yi-Wei Chao, Nathan D. Kenney, Michael R. Mcallaster, Craig B. Wilen, Peter A. White, Jason M. Mackenzie

Open Access Publications

No abstract provided.

Clinical And Genomic Risk To Guide The Use Of Adjuvant Therapy For Breast Cancer, Matthew J. Ellis, Et Al.

Open Access Publications

No abstract provided.

Single-Cell Receptor Quantification Of An In Vitro Coculture Angiogenesis Model Reveals Vegfr, Nrp1, Tie2, And Pdgfr Regulation And Endothelial Heterogeneity, Si Chen, P. I. Imoukhuede

Open Access Publications

No abstract provided.

Rehabilitation Predictors Of Clinical Outcome Following Revision Acl Reconstruction In The Mars Cohort, Rick W. Wright, Mars Group

Open Access Publications

No abstract provided.

Assessment Of Progress In Education For Children And Youth With Disabilities In Afghanistan: A Multilevel Analysis Of Repeated Cross-Sectional Surveys, Jean-Francois Trani, Patrick Fowler, Parul Bakhshi, Praveen Kumar

Open Access Publications

No abstract provided.

Mechanism Of Action Of Vp1-001 In Cryab(R120g)-Associated And Age-Related Cataracts, Kathleen S. Molnar, Bryan M. Dunyak, Bonnie Su, Yevgeniy Izrayelit, Brittney Mcglasson-Naumann, Paul D. Hamilton, Mingxing Qian, Douglas F. Covey, Jason E. Gestwicki, Leah N. Makley, Usha P. Andley

Open Access Publications

No abstract provided.

Feedback Regulation Of Arid5a And Ppar-Γ2 Maintains Adipose Tissue Homeostasis, Jaya Prakash Chalise, Shigeru Hashimoto, Gyanu Parajuli, Sujin Kang, Shailendra Kumar Singh, Yohannes Gemechu, Hozaifa Metwally, Kishan Kumar Nyati, Praveen Kumar Dubey, Mohammad Mahabub-Uz Zaman, Yasuharu Nagahama, Hanieh Hamza, Kazuya Masuda, Tadamitsu Kishimoto

Open Access Publications

No abstract provided.

Zmym2 Inhibits Nanog-Mediated Reprogramming [Version 1; Peer Review: 2 Approved, 1 Approved With Reservations], Moyra Lawrence, Thorold W. Theunissen, Patrick Lombard, David J. Adams, Jose C.R. Silva

Open Access Publications

No abstract provided.

Coronary Artery Disease Risk And Lipidomic Profiles Are Similar In Hyperlipidemias With Family History And Population-Ascertained Hyperlipidemias, Nathan O. Stitziel, Et Al

Open Access Publications

No abstract provided.

Mind The Gap! Extraluminal Percutaneous-Endoscopic Rendezvous With A Self-Expanding Metal Stent For Restoring Continuity In Major Bile Duct Injury: A Case Series, Jessica Lindemann, Christo Kloppers, Sean Burmeister, Marc Bernon, Eduard Jonas

Open Access Publications

No abstract provided.

Crispr/Cas9 Mediated Generation Of An Ovine Model For Infantile Neuronal Ceroid Lipofuscinosis (Cln1 Disease), S. L. Eaton, C. Proudfoot, S. G. Lillico, P. Skehel, R. A. Kline, K. Hamer, N. M. Rzechorzek, E. Clutton, R. Gregson, T. King, C. A. O'Neill, J. D. Cooper, G. Thompson, C. B. Whitelaw, T. M. Wishart

Open Access Publications

No abstract provided.

Pediatric Tropical Medicine: The Neglected Diseases Of Children, Peter J. Hotez, Audrey R. Odom John, A. Desiree Labeaud

Open Access Publications

No abstract provided.

Effectiveness Of Postoperative Radiotherapy After Radical Cystectomy For Locally Advanced Bladder Cancer, Benjamin W. Fischer-Valuck, Jeff M. Michalski, Todd A. Dewees, Eric Kim, Zachary L. Smith, Gerald L. Andriole, Vivek Arora, Arnold Bullock, Robert S. Figenshau, Robert L. Grubb, Eric M. Knoche, Russell K. Pachynski, Bruce J. Roth, Hiram A. Gay, Brian C. Baumann, Et Al

Open Access Publications

No abstract provided.

Combined Esophacap Cytology And Muc2 Immunohistochemistry For Screening Of Intestinal Metaplasia, Dysplasia And Carcinoma, Zhongren Zhou, Irina Kalatskaya, Donna Russell, Norman Marcon, Maria Cirocco, Paul M. Krzyzanowski, Cathy Streutker, Hua Liang, Virginia R. Litle, Tony E. Godfrey, Lincoln Stein

Open Access Publications

No abstract provided.

The Effects Of Aging On Sleep Parameters In A Healthy, Melatonin-Competent Mouse Model, Jiffin K. Paulose, Chanung Wang, Bruce F. O'Hara, Vincent M. Cassone

Open Access Publications

No abstract provided.

Recommendations For The Management Of Elevated Intraocular Pressure Due To Bleb Fibrosis After Xen Gel Stent Implantation, Vanessa Vera, Arsham Sheybani, Dan Lindfield, Ingeborg Stalmans, Iqbal Ike K. Ahmed

Open Access Publications

No abstract provided.

Implementation Science For The Bedside, Elvin H. Geng

Open Access Publications

No abstract provided.

Covalently-Assembled Single-Chain Protein Nanostructures With Ultra-High Stability, Wenqin Bai, Cameron J. Sargent, Jeong-Mo Choi, Rohit V. Pappu, Fuzhong Zhang

Open Access Publications

No abstract provided.

(5r)-5-Hydroxytriptolide (Lldt8) Induces Substantial Epigenetic Mediated Immune Response Network Changes In Fibroblast-Like Synoviocytes From Rheumatoid Arthritis Patients, Grace Wang, Et Al.

Open Access Publications

No abstract provided.

Measuring The Quality Of Multi-Disciplinary Thoracic Oncology Care, Elliot Wakeam, David Odell, Pamela Samson

Open Access Publications

No abstract provided.