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Th17 Cells Are More Protective Than Th1 Cells Against The Intracellular Parasite Trypanosoma Cruzi, Catherine W. Cai, Jennifer R. Blase, Xiuli Zhang, Christopher S. Eickhoff, Daniel F. Hoft Jan 2016

Th17 Cells Are More Protective Than Th1 Cells Against The Intracellular Parasite Trypanosoma Cruzi, Catherine W. Cai, Jennifer R. Blase, Xiuli Zhang, Christopher S. Eickhoff, Daniel F. Hoft

Open Access Publications

No abstract provided.


Antibody-Based Therapy For Enterococcal Catheter-Associated Urinary Tract Infections, Ana L. Flores-Mireles, Jennifer N. Walker, Aaron Potretzke, Henry L. Schreiber Iv, Jerome S. Pinkner, Tyler M. Bauman, Alyssa M. Park, Alana Desai, Scott J. Hultgren, Michael G. Caparon Jan 2016

Antibody-Based Therapy For Enterococcal Catheter-Associated Urinary Tract Infections, Ana L. Flores-Mireles, Jennifer N. Walker, Aaron Potretzke, Henry L. Schreiber Iv, Jerome S. Pinkner, Tyler M. Bauman, Alyssa M. Park, Alana Desai, Scott J. Hultgren, Michael G. Caparon

Open Access Publications

No abstract provided.


Cox-2 Inhibition Reduces Brucella Bacterial Burden In Draining Lymph Nodes, Aurelie Gagnaire, Laurent Gorvel, Alexia Papadopoulos, Kristine Von Bargen, Jean-Louis Mege, Jean-Pierre Gorvel Jan 2016

Cox-2 Inhibition Reduces Brucella Bacterial Burden In Draining Lymph Nodes, Aurelie Gagnaire, Laurent Gorvel, Alexia Papadopoulos, Kristine Von Bargen, Jean-Louis Mege, Jean-Pierre Gorvel

Open Access Publications

No abstract provided.


Evaluation Of Machine Learning And Rules-Based Approaches For Predicting Antimicrobial Resistance Profiles In Gram-Negative Bacilli From Whole Genome Sequence Data, Mitchell W. Pesesky, Tahir Hussain, Meghan Wallace, Sanket Patel, Saadia Andleeb, Carey-Ann D. Burhnam, Gautam Dantas Jan 2016

Evaluation Of Machine Learning And Rules-Based Approaches For Predicting Antimicrobial Resistance Profiles In Gram-Negative Bacilli From Whole Genome Sequence Data, Mitchell W. Pesesky, Tahir Hussain, Meghan Wallace, Sanket Patel, Saadia Andleeb, Carey-Ann D. Burhnam, Gautam Dantas

Open Access Publications

No abstract provided.


Dictyocaulus Viviparus Genome, Variome And Transcriptome Elucidate Lungworm Biology And Support Future Intervention, Samantha N. Mcnulty, Christina Strube, Bruce A. Rosa, John C. Martin, Rahul Tyagi, Young-Jun Choi, Qi Wang, Kymberlie Hallsworth Pepin, Xu Zhang, Philip Ozersky, Richard K. Wilson, Paul W. Sternberg, Robin B. Gasser, Makedonka Mitreva Jan 2016

Dictyocaulus Viviparus Genome, Variome And Transcriptome Elucidate Lungworm Biology And Support Future Intervention, Samantha N. Mcnulty, Christina Strube, Bruce A. Rosa, John C. Martin, Rahul Tyagi, Young-Jun Choi, Qi Wang, Kymberlie Hallsworth Pepin, Xu Zhang, Philip Ozersky, Richard K. Wilson, Paul W. Sternberg, Robin B. Gasser, Makedonka Mitreva

Open Access Publications

No abstract provided.


A Critical Review Of Perfluorooctanoate And Perfluorooctanesulfonate Exposure And Immunological Health Conditions In Humans, Ellen T. Chang, Hans-Olov Adami, Paolo Boffetta, H. James Wedner, Jack S. Mandel Jan 2016

A Critical Review Of Perfluorooctanoate And Perfluorooctanesulfonate Exposure And Immunological Health Conditions In Humans, Ellen T. Chang, Hans-Olov Adami, Paolo Boffetta, H. James Wedner, Jack S. Mandel

Open Access Publications

No abstract provided.


Human And Murine Ifit1 Proteins Do Not Restrict Infection Of Negative-Sense Rna Viruses Of The Orthomyxoviridae, Bunyaviridae, And Filoviridae Families, Amelia K. Pinto, Graham D. Williams, Kristy J. Szretter, James P. White, José Luiz Proença-Módena, Gai Liu, Judith Olejnik, James D. Brien, Hideki Ebihara, Elke Mühlberger, Gaya Amarasinghe, Michael S. Diamond, Adrianus C.M. Boon Sep 2015

Human And Murine Ifit1 Proteins Do Not Restrict Infection Of Negative-Sense Rna Viruses Of The Orthomyxoviridae, Bunyaviridae, And Filoviridae Families, Amelia K. Pinto, Graham D. Williams, Kristy J. Szretter, James P. White, José Luiz Proença-Módena, Gai Liu, Judith Olejnik, James D. Brien, Hideki Ebihara, Elke Mühlberger, Gaya Amarasinghe, Michael S. Diamond, Adrianus C.M. Boon

Open Access Publications

UNLABELLED: Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) is a host protein with reported cell-intrinsic antiviral activity against several RNA viruses. The proposed basis for the activity against negative-sense RNA viruses is the binding to exposed 5'-triphosphates (5'-ppp) on the genome of viral RNA. However, recent studies reported relatively low binding affinities of IFIT1 for 5'-ppp RNA, suggesting that IFIT1 may not interact efficiently with this moiety under physiological conditions. To evaluate the ability of IFIT1 to have an impact on negative-sense RNA viruses, we infected Ifit1(-/-) and wild-type control mice and primary cells with four negative-sense RNA viruses (influenza …


Clostridium Difficile Infection Among Veterans Health Administration Patients, Yinong Young-Xu, Jennifer L. Kuntz, Dale N. Gerding, Julia Neily, Peter Mills, Erik R. Dubberke, Margaret A. Olsen, Ciarán P. Kelly, Cédric Mahé Jan 2015

Clostridium Difficile Infection Among Veterans Health Administration Patients, Yinong Young-Xu, Jennifer L. Kuntz, Dale N. Gerding, Julia Neily, Peter Mills, Erik R. Dubberke, Margaret A. Olsen, Ciarán P. Kelly, Cédric Mahé

Open Access Publications

No abstract provided.


Antimicrobial Susceptibility Profiles Of Staphylococcus Aureus Isolates Recovered From Humans, Environmental Surfaces, And Companion Animals In Households Of Children With Community-Onset Methicillin-Resistant S. Aureus Infections, John J. Morelli, Patrick G. Hogan, Melanie L. Sullivan, Carol E. Muenks, Jeffrey W. Wang, Ryley M. Thompson, Carey-Ann D. Burnham, Stephanie A. Fritz Jan 2015

Antimicrobial Susceptibility Profiles Of Staphylococcus Aureus Isolates Recovered From Humans, Environmental Surfaces, And Companion Animals In Households Of Children With Community-Onset Methicillin-Resistant S. Aureus Infections, John J. Morelli, Patrick G. Hogan, Melanie L. Sullivan, Carol E. Muenks, Jeffrey W. Wang, Ryley M. Thompson, Carey-Ann D. Burnham, Stephanie A. Fritz

Open Access Publications

No abstract provided.


Global Analyses Revealed Age-Related Alterations In Innate Immune Responses After Stimulation Of Pathogen Recognition Receptors, Talibah U. Metcalf, Rafael A. Cubas, Khader Ghneim, Michael J. Cartwright, Julien Van Grevenynghe, Justin M. Richner, David P. Olagnier, Peter A. Wilkinson, Mark J. Cameron, Byung S. Park, John B. Hiscott, Michael S. Diamond, Anne M. Wertheimer, Janko Nikolich-Zugich, Elias K. Haddad Jan 2015

Global Analyses Revealed Age-Related Alterations In Innate Immune Responses After Stimulation Of Pathogen Recognition Receptors, Talibah U. Metcalf, Rafael A. Cubas, Khader Ghneim, Michael J. Cartwright, Julien Van Grevenynghe, Justin M. Richner, David P. Olagnier, Peter A. Wilkinson, Mark J. Cameron, Byung S. Park, John B. Hiscott, Michael S. Diamond, Anne M. Wertheimer, Janko Nikolich-Zugich, Elias K. Haddad

Open Access Publications

No abstract provided.


Case Report: Typhoid Fever Complicated By Hemophagocytic Lymphohistiocytosis And Rhabdomyolysis, Lemuel R. Non, Rupa Patel, Amir Esmaeeli, Vladimir Despotovic Jan 2015

Case Report: Typhoid Fever Complicated By Hemophagocytic Lymphohistiocytosis And Rhabdomyolysis, Lemuel R. Non, Rupa Patel, Amir Esmaeeli, Vladimir Despotovic

Open Access Publications

No abstract provided.


Case Report: A Case Of Diabetic Ketoacidosis Following Chikungunya Virus Infection, Illya Tolokh, Timothy Laux, Daniel Kim Jan 2015

Case Report: A Case Of Diabetic Ketoacidosis Following Chikungunya Virus Infection, Illya Tolokh, Timothy Laux, Daniel Kim

Open Access Publications

No abstract provided.


Detailed Phenotypic And Molecular Analyses Of Genetically Modified Mice Generated By Crispr-Cas9-Mediated Editing, Bijal A. Parikh, Diana L. Beckman, Swapneel J. Patel, J. Michael White, Wayne M. Yokoyama Jan 2015

Detailed Phenotypic And Molecular Analyses Of Genetically Modified Mice Generated By Crispr-Cas9-Mediated Editing, Bijal A. Parikh, Diana L. Beckman, Swapneel J. Patel, J. Michael White, Wayne M. Yokoyama

Open Access Publications

No abstract provided.


Criteria For Reducing Unnecessary Testing For Herpes Simplex Virus, Varicella-Zoster Virus, Cytomegalovirus, And Enterovirus In Cerebrospinal Fluid Samples From Adults, Craig B. Wilen, Cynthia L. Monaco, Joan Hoppe-Bauer, Ronald Jackups Jr., Robert C. Bucelli, Carey-Ann D. Burnham Jan 2015

Criteria For Reducing Unnecessary Testing For Herpes Simplex Virus, Varicella-Zoster Virus, Cytomegalovirus, And Enterovirus In Cerebrospinal Fluid Samples From Adults, Craig B. Wilen, Cynthia L. Monaco, Joan Hoppe-Bauer, Ronald Jackups Jr., Robert C. Bucelli, Carey-Ann D. Burnham

Open Access Publications

No abstract provided.


Species-Specific Transmission Of Novel Picornaviruses In Lemurs, Efrem S. Lim, Sharon L. Deem, Ingrid J. Porton, Song Cao, David Wang Jan 2015

Species-Specific Transmission Of Novel Picornaviruses In Lemurs, Efrem S. Lim, Sharon L. Deem, Ingrid J. Porton, Song Cao, David Wang

Open Access Publications

No abstract provided.


Stratification Of Surgical Site Infection By Operative Factors And Comparison Of Infection Rates After Hernia Repair, Margaret A. Olsen, Katelin B. Nickel, Anna E. Wallace, Daniel Mines, Victoria J. Fraser, David K. Warren Jan 2015

Stratification Of Surgical Site Infection By Operative Factors And Comparison Of Infection Rates After Hernia Repair, Margaret A. Olsen, Katelin B. Nickel, Anna E. Wallace, Daniel Mines, Victoria J. Fraser, David K. Warren

Open Access Publications

No abstract provided.


Metabolic And Metagenomic Outcomes From Early-Life Pulsed Antibiotic Treatment, Sahar Abubucker, Yanjiao Zhou, Makedonka Mitreva, George M. Weinstock, Erica Sodergren, Et Al Jan 2015

Metabolic And Metagenomic Outcomes From Early-Life Pulsed Antibiotic Treatment, Sahar Abubucker, Yanjiao Zhou, Makedonka Mitreva, George M. Weinstock, Erica Sodergren, Et Al

Open Access Publications

No abstract provided.


Brown-Pigmented Mycobacterium Mageritense As A Cause Of Prosthetic Valve Endocarditis And Bloodstream Infection, Allison R. Mcmullen, Caline Mattar, Nigar Kirmani, Carey-Ann D. Burnham Jan 2015

Brown-Pigmented Mycobacterium Mageritense As A Cause Of Prosthetic Valve Endocarditis And Bloodstream Infection, Allison R. Mcmullen, Caline Mattar, Nigar Kirmani, Carey-Ann D. Burnham

Open Access Publications

No abstract provided.


Genome Sequence Of Enterovirus D68 From St. Louis, Missouri, Usa, Kristine M. Wylie, Todd N. Wylie, Anthony Orvedahl, Richard S. Buller, Brandi N. Herter, Vincent Magrini, Richard K. Wilson, Gregory A. Storch Jan 2015

Genome Sequence Of Enterovirus D68 From St. Louis, Missouri, Usa, Kristine M. Wylie, Todd N. Wylie, Anthony Orvedahl, Richard S. Buller, Brandi N. Herter, Vincent Magrini, Richard K. Wilson, Gregory A. Storch

Open Access Publications

No abstract provided.


Wu Polyomavirus In Respiratory Epithelial Cells From Lung Transplant Patient With Job Syndrome, Erica A. Siebrasse, Nang L. Nguyen, Annie Wang, David Wang, Diana V. Pastrana, Mark J. Roth, Steven M. Holland, Alexandra F. Freeman, Christopher B. Buck, John Mcdyer Jan 2015

Wu Polyomavirus In Respiratory Epithelial Cells From Lung Transplant Patient With Job Syndrome, Erica A. Siebrasse, Nang L. Nguyen, Annie Wang, David Wang, Diana V. Pastrana, Mark J. Roth, Steven M. Holland, Alexandra F. Freeman, Christopher B. Buck, John Mcdyer

Open Access Publications

No abstract provided.


Two Potential Hookworm Daf-16 Target Genes, Snr-3 And Lpp-1: Gene Structure, Expression Profile, And Implications Of A Cis-Regulatory Element In The Regulation Of Gene Expression, Xin Gao, Kevin Goggin, Jason Qian, John M. Hawdon Jan 2015

Two Potential Hookworm Daf-16 Target Genes, Snr-3 And Lpp-1: Gene Structure, Expression Profile, And Implications Of A Cis-Regulatory Element In The Regulation Of Gene Expression, Xin Gao, Kevin Goggin, Jason Qian, John M. Hawdon

Open Access Publications

No abstract provided.


Uropathogenic Escherichia Coli Superinfection Enhances The Severity Of Mouse Bladder Infection, Drew J. Schwartz, Matt S. Conover, Thomas J. Hannan, Scott J. Hultgren Jan 2015

Uropathogenic Escherichia Coli Superinfection Enhances The Severity Of Mouse Bladder Infection, Drew J. Schwartz, Matt S. Conover, Thomas J. Hannan, Scott J. Hultgren

Open Access Publications

No abstract provided.


Irf-5-Dependent Signaling Restricts Orthobunyavirus Dissemination To The Central Nervous System, Jose Luiz Proenca-Modena, Jennifer L. Hyde, Renata Sesti-Costa, Tiffany Lucas, Amelia K. Pinto, Justin M. Richner, Matthew J. Gorman, Helen M. Lazear, Michael S. Diamond Jan 2015

Irf-5-Dependent Signaling Restricts Orthobunyavirus Dissemination To The Central Nervous System, Jose Luiz Proenca-Modena, Jennifer L. Hyde, Renata Sesti-Costa, Tiffany Lucas, Amelia K. Pinto, Justin M. Richner, Matthew J. Gorman, Helen M. Lazear, Michael S. Diamond

Open Access Publications

No abstract provided.


T Cell Metabolism Drives Immunity, Michael D. Buck, David O'Sullivan, Erika L. Pearce Jan 2015

T Cell Metabolism Drives Immunity, Michael D. Buck, David O'Sullivan, Erika L. Pearce

Open Access Publications

No abstract provided.


Increasing The Reliability Of Fully Automated Surveillance For Central Line–Associated Bloodstream Infections, Rachael E. Snyders, Ashleigh J. Goris, Kathleen A. Gase, Carole L. Leone, Joshua A. Doherty, Keith F. Woeltje Jan 2015

Increasing The Reliability Of Fully Automated Surveillance For Central Line–Associated Bloodstream Infections, Rachael E. Snyders, Ashleigh J. Goris, Kathleen A. Gase, Carole L. Leone, Joshua A. Doherty, Keith F. Woeltje

Open Access Publications

No abstract provided.


Higher Throughput Quantification Of Neutralizing Antibody To Herpes Simplex Viruses, Tamara P. Blevins, Michelle C. Mitchell, Maria Korom, Hong Wang, Yinyi Yu, Lynda A. Morrison, Robert B. Belshe Jan 2015

Higher Throughput Quantification Of Neutralizing Antibody To Herpes Simplex Viruses, Tamara P. Blevins, Michelle C. Mitchell, Maria Korom, Hong Wang, Yinyi Yu, Lynda A. Morrison, Robert B. Belshe

Open Access Publications

No abstract provided.


Inadequate Source Control And Inappropriate Antibiotics Are Key Determinants Of Mortality In Patients With Intra-Abdominal Sepsis And Associated Bacteremia, Bethany Tellor, Lee P. Skrupky, William Symons, Eric High, Scott T. Micek, John E. Mazuski Jan 2015

Inadequate Source Control And Inappropriate Antibiotics Are Key Determinants Of Mortality In Patients With Intra-Abdominal Sepsis And Associated Bacteremia, Bethany Tellor, Lee P. Skrupky, William Symons, Eric High, Scott T. Micek, John E. Mazuski

Open Access Publications

No abstract provided.


Cross-Reactivity Of Filariais Ict Cards In Areas Of Contrasting Endemicity Of Loa Loa And Mansonella Perstans In Cameroon: Implications For Shrinking Of The Lymphatic Filariasis Map In The Central African Region, Samuel Wanji, Nathalie Amvongo-Adjia, Benjamin Koudou, Abdel Jelil Njouendou, Patrick W. Chounna Ndongmo, Jonas A. Kengne-Ouafo, Fabrice R. Datchoua-Poutcheu, Bridget Adzemye Fovennso, Dizzle Bita Tayong, Fanny Fri Fombad, Peter U. Fischer, Peter I. Enyong, Moses Bockarie Jan 2015

Cross-Reactivity Of Filariais Ict Cards In Areas Of Contrasting Endemicity Of Loa Loa And Mansonella Perstans In Cameroon: Implications For Shrinking Of The Lymphatic Filariasis Map In The Central African Region, Samuel Wanji, Nathalie Amvongo-Adjia, Benjamin Koudou, Abdel Jelil Njouendou, Patrick W. Chounna Ndongmo, Jonas A. Kengne-Ouafo, Fabrice R. Datchoua-Poutcheu, Bridget Adzemye Fovennso, Dizzle Bita Tayong, Fanny Fri Fombad, Peter U. Fischer, Peter I. Enyong, Moses Bockarie

Open Access Publications

No abstract provided.


Physical Activity Affects Brain Integrity In Hiv+ Individuals, Mario Ortega, Laurie M. Baker, Florin Vaida, Robert Paul, Brian Basco, Beau M. Ances Jan 2015

Physical Activity Affects Brain Integrity In Hiv+ Individuals, Mario Ortega, Laurie M. Baker, Florin Vaida, Robert Paul, Brian Basco, Beau M. Ances

Open Access Publications

No abstract provided.


Discriminatory Indices Of Typing Methods For Epidemiologic Analysis Of Contemporary Staphylococcus Aureus Strains, Marcela Rodriguez, Patrick G. Hogan, Sarah W. Satola, Emily Crispell, Todd Wylie, Hongyu Gao, Erica Sodergren, George M. Weinstock, Carey-Ann D. Burnham, Stephanie A. Fritz Jan 2015

Discriminatory Indices Of Typing Methods For Epidemiologic Analysis Of Contemporary Staphylococcus Aureus Strains, Marcela Rodriguez, Patrick G. Hogan, Sarah W. Satola, Emily Crispell, Todd Wylie, Hongyu Gao, Erica Sodergren, George M. Weinstock, Carey-Ann D. Burnham, Stephanie A. Fritz

Open Access Publications

No abstract provided.