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Articles 5761 - 5790 of 7412
Full-Text Articles in Entire DC Network
Incidence Of Symptomatic Venous Thromboembolism In Oncologic Patients Undergoing Lower-Extremity Endoprosthetic Arthroplasty, Brandon A. Ramo, Anthony M. Griffin, Corey S. Gill, Douglas J. Mcdonald, Jay S. Wunder, Peter Ferguson, Robert S. Bell, Sharon E. Phillips, Herbert S. Schwartz, Ginger E. Holt
Incidence Of Symptomatic Venous Thromboembolism In Oncologic Patients Undergoing Lower-Extremity Endoprosthetic Arthroplasty, Brandon A. Ramo, Anthony M. Griffin, Corey S. Gill, Douglas J. Mcdonald, Jay S. Wunder, Peter Ferguson, Robert S. Bell, Sharon E. Phillips, Herbert S. Schwartz, Ginger E. Holt
Open Access Publications
No abstract provided.
Radiographic Structural Abnormalities Associated With Premature, Natural Hip-Joint Failure, John C. Clohisy, Michael A. Dobson, Jason F. Robison, Lucian C. Warth, Jie Zheng, Steve S. Liu, Tameem M. Yehyawi, John J. Callaghan
Radiographic Structural Abnormalities Associated With Premature, Natural Hip-Joint Failure, John C. Clohisy, Michael A. Dobson, Jason F. Robison, Lucian C. Warth, Jie Zheng, Steve S. Liu, Tameem M. Yehyawi, John J. Callaghan
Open Access Publications
No abstract provided.
Dehydroepiandrosterone (Dhea) Replacement Decreases Insulin Resistance And Lowers Inflammatory Cytokines In Aging Humans, Edward P. Weiss, Dennis T. Villareal, Luigi Fontana, Dong-Ho Han, John O. Holloszy
Dehydroepiandrosterone (Dhea) Replacement Decreases Insulin Resistance And Lowers Inflammatory Cytokines In Aging Humans, Edward P. Weiss, Dennis T. Villareal, Luigi Fontana, Dong-Ho Han, John O. Holloszy
Open Access Publications
Plasma dehydroepiandrosterone (DHEA) decreases ~80% between ages 25 and 75 yr. In a preliminary study, we found that 6 mo of DHEA replacement improved insulin action in elderly individuals. The purpose of the present larger, randomized double-blind study was to determine whether a longer period of DHEA replacement improves glucose tolerance. Fifty-seven men and 68 women aged 65 to 75 yr were randomly assigned to 50 mg DHEA or placebo once daily. Year one was a randomized, double blind trial. Year 2 was an open label continuation. DHEA replacement improved glucose tolerance in participants who had abnormal GT initially, reduced …
Managing Stress In The Orthopaedic Family: Avoiding Burnout, Achieving Resilience, M. Catherine Sargent, Wayne Sotile, Mary O. Sotile, Harry Rubash, Peter S. Vezeridis, Larry Harmon, Robert L. Barrack
Managing Stress In The Orthopaedic Family: Avoiding Burnout, Achieving Resilience, M. Catherine Sargent, Wayne Sotile, Mary O. Sotile, Harry Rubash, Peter S. Vezeridis, Larry Harmon, Robert L. Barrack
Open Access Publications
No abstract provided.
Congenital Bone Marrow Failure In Dna-Pkcs Mutant Mice Associated With Deficiencies In Dna Repair, Shichuan Zhang, Hirohiko Yajima, Hoangdinh Huynh, Junke Zheng, Elsa Callen, Hua-Tang Chen, Nancy Wong, Samuel Bunting, Yu-Fen Lin, Mengxia Li, Kyung-Jone Lee, Michael Story, Eric Gapud, Barry P. Sleckman, André Nussenzweig, Cheng Cheng Zhang, David J. Chen, Benjamin P.C. Chen
Congenital Bone Marrow Failure In Dna-Pkcs Mutant Mice Associated With Deficiencies In Dna Repair, Shichuan Zhang, Hirohiko Yajima, Hoangdinh Huynh, Junke Zheng, Elsa Callen, Hua-Tang Chen, Nancy Wong, Samuel Bunting, Yu-Fen Lin, Mengxia Li, Kyung-Jone Lee, Michael Story, Eric Gapud, Barry P. Sleckman, André Nussenzweig, Cheng Cheng Zhang, David J. Chen, Benjamin P.C. Chen
Open Access Publications
No abstract provided.
A Behavioral Analysis Of Spatial Neglect And Its Recovery After Stroke, Jennifer Rengachary, Biyu J. He, Gordon L. Shulman, Maurizio Corbetta
A Behavioral Analysis Of Spatial Neglect And Its Recovery After Stroke, Jennifer Rengachary, Biyu J. He, Gordon L. Shulman, Maurizio Corbetta
Open Access Publications
No abstract provided.
Long-Term Calorie Restriction, But Not Endurance Exercise, Lowers Core Body Temperature In Humans, Andreea Soare, Roberto Cangemi, Daniela Omodei, John O. Holloszy, Luigi Fontana
Long-Term Calorie Restriction, But Not Endurance Exercise, Lowers Core Body Temperature In Humans, Andreea Soare, Roberto Cangemi, Daniela Omodei, John O. Holloszy, Luigi Fontana
Open Access Publications
Reduction of body temperature has been proposed to contribute to the increased lifespan in calorie restricted animals and mice overexpressing the uncoupling protein-2 in hypocretin neurons. However, nothing is known regarding the long-term effects of calorie restriction (CR) with adequate nutrition on body temperature in humans. In this study, 24-hour core body temperature was measured every minute by using ingested telemetric capsules in 24 men and women (mean age 53.7 ± 9.4 yrs) consuming a CR diet for an average of 6 years, 24 age- and sex-matched sedentary (WD) and 24 body fat-matched exercise-trained (EX) volunteers, who were eating Western …
Episodic Memory Retrieval, Parietal Cortex, And The Default Mode Network: Functional And Topographic Analyses, Carlo Sestieri, Maurizio Corbetta, Gian Luca Romani, Gordon L. Shulman
Episodic Memory Retrieval, Parietal Cortex, And The Default Mode Network: Functional And Topographic Analyses, Carlo Sestieri, Maurizio Corbetta, Gian Luca Romani, Gordon L. Shulman
Open Access Publications
The default mode network (DMN) is often considered a functionally homogeneous system that is broadly associated with internally directed cognition (e.g., episodic memory, theory of mind, self-evaluation). However, few studies have examined how this network interacts with other networks during putative "default" processes such as episodic memory retrieval. Using functional magnetic resonance imaging, we investigated the topography and response profile of human parietal regions inside and outside the DMN, independently defined using task-evoked deactivations and resting-state functional connectivity, during episodic memory retrieval. Memory retrieval activated posterior nodes of the DMN, particularly the angular gyrus, but also more anterior and dorsal …
The Cytoplasmic Adaptor Protein Caskin Mediates Lar Signal Transduction During Drosophila Motor Axon Guidance, Yi-Lan Weng, Nan Liu, Aaron Diantonio, Heather T. Broihier
The Cytoplasmic Adaptor Protein Caskin Mediates Lar Signal Transduction During Drosophila Motor Axon Guidance, Yi-Lan Weng, Nan Liu, Aaron Diantonio, Heather T. Broihier
Open Access Publications
The multiprotein complexes that receive and transmit axon pathfinding cues during development are essential to circuit generation. Here, we identify and characterize the Drosophila sterile α-motif (SAM) domain-containing protein Caskin, which shares homology with vertebrate Caskin, a CASK [calcium/calmodulin-(CaM)-activated serine-threonine kinase]-interacting protein. Drosophila caskin (ckn) is necessary for embryonic motor axon pathfinding and interacts genetically and physically with the leukocyte common antigen-related (Lar) receptor protein tyrosine phosphatase. In vivo and in vitro analyses of a panel of ckn loss-of-function alleles indicate that the N-terminal SAM domain of Ckn mediates its interaction with Lar. Like Caskin, Liprin-α is a neuronal adaptor …
Functional Analysis Of Novel Analogues Of E3330 That Block The Redox Signaling Activity Of The Multifunctional Ap Endonuclease/Redox Signaling Enzyme Ape1/Ref-1, Mark R. Kelley, Meihua Luo, April Reed, Dian Su, Sarah Delaplane, Richard F. Borch, Rodney L. Nyland Ii, Michael L. Gross, Millie M. Georgiadis
Functional Analysis Of Novel Analogues Of E3330 That Block The Redox Signaling Activity Of The Multifunctional Ap Endonuclease/Redox Signaling Enzyme Ape1/Ref-1, Mark R. Kelley, Meihua Luo, April Reed, Dian Su, Sarah Delaplane, Richard F. Borch, Rodney L. Nyland Ii, Michael L. Gross, Millie M. Georgiadis
Open Access Publications
No abstract provided.
Myxoid Chondrosarcoma Of The Phalanx With An Ews Translocation: A Case Report And Review Of The Literature, David B. Bumpass, Michael Kyriakos, David A. Rubin, Paul R. Manske, Charles A. Goldfarb
Myxoid Chondrosarcoma Of The Phalanx With An Ews Translocation: A Case Report And Review Of The Literature, David B. Bumpass, Michael Kyriakos, David A. Rubin, Paul R. Manske, Charles A. Goldfarb
Open Access Publications
No abstract provided.
Are Dropped Osteoarticular Bone Fragments Safely Reimplantable In Vivo?, Benjamin Bruce, Shahin Sheibani-Rad, Deborah Appleyard, Ryan P. Calfee, Steven E. Reinert, Kimberle C. Chapin, Christopher W. Digiovanni
Are Dropped Osteoarticular Bone Fragments Safely Reimplantable In Vivo?, Benjamin Bruce, Shahin Sheibani-Rad, Deborah Appleyard, Ryan P. Calfee, Steven E. Reinert, Kimberle C. Chapin, Christopher W. Digiovanni
Open Access Publications
No abstract provided.
Igh Gene Rearrangements As Plasma Biomarkers In Non- Hodgkin's Lymphoma Patients, Jian He, Jian Wu, Yuchen Jiao, Nina Wagner-Johnston, Richard F. Ambinder, Luis A. Diaz, Kenneth W. Kinzler, Bert Vogelstein, Nickolas Papadopoulos
Igh Gene Rearrangements As Plasma Biomarkers In Non- Hodgkin's Lymphoma Patients, Jian He, Jian Wu, Yuchen Jiao, Nina Wagner-Johnston, Richard F. Ambinder, Luis A. Diaz, Kenneth W. Kinzler, Bert Vogelstein, Nickolas Papadopoulos
Open Access Publications
New biomarkers with improved accuracy could be helpful for monitoring disease in patients with Non-Hodgkin's lymphomas (NHL). Towards this end, we have explored the feasibility of identifying the sequence of rearranged IgH genes using next-generation sequencing, then using PCR to detect specific rearranged DNA fragments in patients' plasma. By capturing and sequencing the IgH genomic regions (IgCap), we were able to detect and precisely determine the sequence of rearranged IgH loci in the tumors of three NHL patients. Moreover, circulating rearranged DNA fragments could be identified in the plasma of all three patients. Even in cases wherein tumor biopsies were …
Effect Of Short-Duration Low-Magnitude Cyclic Loading Versus Immobilization On Tendon-Bone Healing After Acl Reconstruction In A Rat Model, Robert H. Brophy, David Kovacevic, Carl W. Imhauser, Mark Stasiak, Asheesh Bedi, Alice J.S. Fox, Xiang-Hua Deng, Scott A. Rodeo
Effect Of Short-Duration Low-Magnitude Cyclic Loading Versus Immobilization On Tendon-Bone Healing After Acl Reconstruction In A Rat Model, Robert H. Brophy, David Kovacevic, Carl W. Imhauser, Mark Stasiak, Asheesh Bedi, Alice J.S. Fox, Xiang-Hua Deng, Scott A. Rodeo
Open Access Publications
No abstract provided.
Nonuniform High-Gamma (60-500 Hz) Power Changes Dissociate Cognitive Task And Anatomy In Human Cortex, Charles M. Gaona, Mohit Sharma, Zachary V. Freudenburg, Jonathan D. Breshears, David T. Bundy, Jarod Roland, Dennis L. Barbour, Gerwin Schalk, Eric C. Leuthardt
Nonuniform High-Gamma (60-500 Hz) Power Changes Dissociate Cognitive Task And Anatomy In Human Cortex, Charles M. Gaona, Mohit Sharma, Zachary V. Freudenburg, Jonathan D. Breshears, David T. Bundy, Jarod Roland, Dennis L. Barbour, Gerwin Schalk, Eric C. Leuthardt
Open Access Publications
High-gamma-band (>60 Hz) power changes in cortical electrophysiology are a reliable indicator of focal, event-related cortical activity. Despite discoveries of oscillatory subthreshold and synchronous suprathreshold activity at the cellular level, there is an increasingly popular view that high-gamma-band amplitude changes recorded from cellular ensembles are the result of asynchronous firing activity that yields wideband and uniform power increases. Others have demonstrated independence of power changes in the low- and high-gamma bands, but to date, no studies have shown evidence of any such independence above 60 Hz. Based on nonuniformities in time-frequency analyses of electrocorticographic (ECoG) signals, we hypothesized that …
Calcium-Independent Inhibitory G-Protein Signaling Induces Persistent Presynaptic Muting Of Hippocampal Synapses, Devon C. Crawford, Chun Yun Chang, Krzysztof L. Hyrc, Steven Mennerick
Calcium-Independent Inhibitory G-Protein Signaling Induces Persistent Presynaptic Muting Of Hippocampal Synapses, Devon C. Crawford, Chun Yun Chang, Krzysztof L. Hyrc, Steven Mennerick
Open Access Publications
Adaptive forms of synaptic plasticity that reduce excitatory synaptic transmission in response to prolonged increases in neuronal activity may prevent runaway positive feedback in neuronal circuits. In hippocampal neurons, for example, glutamatergic presynaptic terminals are selectively silenced, creating "mute" synapses, after periods of increased neuronal activity or sustained depolarization. Previous work suggests that cAMP-dependent and proteasome-dependent mechanisms participate in silencing induction by depolarization, but upstream activators are unknown. We, therefore, tested the role of calcium and G-protein signaling in silencing induction in cultured hippocampal neurons. We found that silencing induction by depolarization was not dependent on rises in intracellular calcium, …
In Vitro And In Vivo Evaluation Of 64cu-Radiolabeled Kccysl Peptides For Targeting Epidermal Growth Factor Receptor-2 In Breast Carcinomas, Senthil R. Kumar, Fabio A. Gallazzi, Riccardo Ferdani, Carolyn J. Anderson, Thomas P. Quinn, Susan L. Deutscher
In Vitro And In Vivo Evaluation Of 64cu-Radiolabeled Kccysl Peptides For Targeting Epidermal Growth Factor Receptor-2 In Breast Carcinomas, Senthil R. Kumar, Fabio A. Gallazzi, Riccardo Ferdani, Carolyn J. Anderson, Thomas P. Quinn, Susan L. Deutscher
Open Access Publications
No abstract provided.
Changes In Events Alter How People Remember Recent Information, Khena M. Swallow, Deanna M. Barch, Denise Head, Corey J. Maley, Derek Holder, Jeffrey M. Zacks
Changes In Events Alter How People Remember Recent Information, Khena M. Swallow, Deanna M. Barch, Denise Head, Corey J. Maley, Derek Holder, Jeffrey M. Zacks
Open Access Publications
No abstract provided.
Improving Salmonella Vector With Rec Mutation To Stabilize The Dna Cargoes, Xiangmin Zhang, Soo-Young Wanda, Karen Brenneman, Wei Kong, Xin Zhang, Kenneth Roland, Roy Curtiss Iii
Improving Salmonella Vector With Rec Mutation To Stabilize The Dna Cargoes, Xiangmin Zhang, Soo-Young Wanda, Karen Brenneman, Wei Kong, Xin Zhang, Kenneth Roland, Roy Curtiss Iii
Open Access Publications
No abstract provided.
Pcr-Based Genotyping Of Helicobacter Pylori Of Gambian Children And Adults Directly From Biopsy Specimens And Bacterial Cultures, Ousman Secka, Martin Antonio, Mary Tapgun, Douglas E. Berg, Christian Bottomley, Vivat Thomas, Robert Walton, Tumani Corrah, Richard A. Adegbola, Julian E. Thomas
Pcr-Based Genotyping Of Helicobacter Pylori Of Gambian Children And Adults Directly From Biopsy Specimens And Bacterial Cultures, Ousman Secka, Martin Antonio, Mary Tapgun, Douglas E. Berg, Christian Bottomley, Vivat Thomas, Robert Walton, Tumani Corrah, Richard A. Adegbola, Julian E. Thomas
Open Access Publications
No abstract provided.
Vacuolization Of Mucolipidosis Type Ii Mouse Exocrine Gland Cells Represents Accumulation Of Autolysosomes, Marielle Boonen, Eline Van Meel, Viola Oorschot, Judith Klumperman, Stuart Kornfeld
Vacuolization Of Mucolipidosis Type Ii Mouse Exocrine Gland Cells Represents Accumulation Of Autolysosomes, Marielle Boonen, Eline Van Meel, Viola Oorschot, Judith Klumperman, Stuart Kornfeld
Open Access Publications
No abstract provided.
Differential Regional And Subtype-Specific Vulnerability Of Enteric Neurons To Mitochondrial Dysfunction, Andreu Viader, Elizabeth C. Wright-Jin, Bhupinder P.S Vohra, Robert O. Heuckeroth, Jeffrey Milbrandt
Differential Regional And Subtype-Specific Vulnerability Of Enteric Neurons To Mitochondrial Dysfunction, Andreu Viader, Elizabeth C. Wright-Jin, Bhupinder P.S Vohra, Robert O. Heuckeroth, Jeffrey Milbrandt
Open Access Publications
No abstract provided.
Fatty-Acid Binding Proteins Modulate Sleep And Enhance Long-Term Memory Consolidation In Drosophila, Jason R. Gerstner, William M. Vanderheyden, Paul J. Shaw, Charles F. Landry, Jerry C. P. Yin
Fatty-Acid Binding Proteins Modulate Sleep And Enhance Long-Term Memory Consolidation In Drosophila, Jason R. Gerstner, William M. Vanderheyden, Paul J. Shaw, Charles F. Landry, Jerry C. P. Yin
Open Access Publications
No abstract provided.
Transcriptome Analysis Of Female And Male Xiphophorus Maculatus Jp 163 A, Ziping Zhang, Yilei Wang, Shuhong Wang, Jingtao Liu, Wesley Warren, Makedonka Mitreva, Ronald B. Walter
Transcriptome Analysis Of Female And Male Xiphophorus Maculatus Jp 163 A, Ziping Zhang, Yilei Wang, Shuhong Wang, Jingtao Liu, Wesley Warren, Makedonka Mitreva, Ronald B. Walter
Open Access Publications
No abstract provided.
Lineage Relationship Of Direct-Developing Melanocytes And Melanocyte Stem Cells In The Zebrafish, Robert C. Tryon, Charles W. Higdon, Stephen L. Johnson
Lineage Relationship Of Direct-Developing Melanocytes And Melanocyte Stem Cells In The Zebrafish, Robert C. Tryon, Charles W. Higdon, Stephen L. Johnson
Open Access Publications
No abstract provided.
Bioluminescent Imaging Reveals Divergent Viral Pathogenesis In Two Strains Of Stat1-Deficient Mice, And In Αßγ Interferon Receptor-Deficient Mice, Tracy Jo Pasieka, Lynne Collins, Megan A. O'Connor, Yufei Chen, Zachary M. Parker, Brent L. Berwin, David R. Piwnica-Worms, David A. Leib
Bioluminescent Imaging Reveals Divergent Viral Pathogenesis In Two Strains Of Stat1-Deficient Mice, And In Αßγ Interferon Receptor-Deficient Mice, Tracy Jo Pasieka, Lynne Collins, Megan A. O'Connor, Yufei Chen, Zachary M. Parker, Brent L. Berwin, David R. Piwnica-Worms, David A. Leib
Open Access Publications
No abstract provided.
Diffusion Of Mmps On The Surface Of Collagen Fibrils: The Mobile Cell Surface - Collagen Substratum Interface, Ivan E. Collier, Wesley Legant, Barry Marmer, Olga Lubman, Saveez Saffarian, Tetsuro Wakatsuki, Elliot Elson, Gregory I. Goldberg
Diffusion Of Mmps On The Surface Of Collagen Fibrils: The Mobile Cell Surface - Collagen Substratum Interface, Ivan E. Collier, Wesley Legant, Barry Marmer, Olga Lubman, Saveez Saffarian, Tetsuro Wakatsuki, Elliot Elson, Gregory I. Goldberg
Open Access Publications
No abstract provided.
Representation Of Vestibular And Visual Cues To Self-Motion In Ventral Intraparietal Cortex, Aihua Chen, Gregory C. Deangelis, Dora E. Angelaki
Representation Of Vestibular And Visual Cues To Self-Motion In Ventral Intraparietal Cortex, Aihua Chen, Gregory C. Deangelis, Dora E. Angelaki
Open Access Publications
No abstract provided.
Deriving Measures Of Intensive Care Unit Antimicrobial Use From Computerized Pharmacy Data: Methods, Validation, And Overcoming Barriers, David N. Schwartz, R Scott Evans, Bernard C. Camins, Yosef M. Khan, James F. Lloyd, Nadine Shehab, Kurt Stevenson, Centers For Disease Control And Prevention Epicenter Program
Deriving Measures Of Intensive Care Unit Antimicrobial Use From Computerized Pharmacy Data: Methods, Validation, And Overcoming Barriers, David N. Schwartz, R Scott Evans, Bernard C. Camins, Yosef M. Khan, James F. Lloyd, Nadine Shehab, Kurt Stevenson, Centers For Disease Control And Prevention Epicenter Program
Open Access Publications
No abstract provided.
A Clustering Analysis Of Lipoprotein Diameters In The Metabolic Syndrome, Alexis C. Frazier-Wood, Stephen Glasser, W Timothy Garvey, Edmond K. Kabagambe, Ingrid B. Borecki, Hemant K. Tiwari, Michael Y. Tsai, Paul N. Hopkins, Jose M. Ordovas, Donna K. Arnett
A Clustering Analysis Of Lipoprotein Diameters In The Metabolic Syndrome, Alexis C. Frazier-Wood, Stephen Glasser, W Timothy Garvey, Edmond K. Kabagambe, Ingrid B. Borecki, Hemant K. Tiwari, Michael Y. Tsai, Paul N. Hopkins, Jose M. Ordovas, Donna K. Arnett
Open Access Publications
No abstract provided.