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Comparison Of The Predictive Performance Of The Big, Triss, And Ps09 Score In An Adult Trauma Population Derived From Multiple International Trauma Registries, Thomas Brockamp, Marc Maegele, Christine Gaarder, J. Carel Goslings, Mitchell J. Cohen, Rolf Lefering, Pieter Joosse, Paal A. Naess, Nils O. Skaga, Tahnee Groat, Simon Eaglestone, Matthew A. Borgman, Philip C. Spinella, Martin A. Schreiber, Karim Brohi Jan 2013

Comparison Of The Predictive Performance Of The Big, Triss, And Ps09 Score In An Adult Trauma Population Derived From Multiple International Trauma Registries, Thomas Brockamp, Marc Maegele, Christine Gaarder, J. Carel Goslings, Mitchell J. Cohen, Rolf Lefering, Pieter Joosse, Paal A. Naess, Nils O. Skaga, Tahnee Groat, Simon Eaglestone, Matthew A. Borgman, Philip C. Spinella, Martin A. Schreiber, Karim Brohi

Open Access Publications

No abstract provided.


Individual Variations In Serum Melatonin Levels Through Time: Implications For Epidemiologic Studies, Leticia M. Nogueira, Joshua N. Sampson, Lisa W. Chu, Kai Yu, Gerald Andriole, Timothy Church, Fank Z. Stanczyk, Jill Koshiol, Ann W. Hsing Jan 2013

Individual Variations In Serum Melatonin Levels Through Time: Implications For Epidemiologic Studies, Leticia M. Nogueira, Joshua N. Sampson, Lisa W. Chu, Kai Yu, Gerald Andriole, Timothy Church, Fank Z. Stanczyk, Jill Koshiol, Ann W. Hsing

Open Access Publications

No abstract provided.


Impact Of Six Rounds Of Mass Drug Administration On Brugian Filariasis And Soil-Transmitted Helminth Infections In Eastern Indonesia, Taniawati Supali, Yenny Djuardi, Mark Bradley, Rahmah Noordin, Paul Ruckert, Peter U. Fischer Jan 2013

Impact Of Six Rounds Of Mass Drug Administration On Brugian Filariasis And Soil-Transmitted Helminth Infections In Eastern Indonesia, Taniawati Supali, Yenny Djuardi, Mark Bradley, Rahmah Noordin, Paul Ruckert, Peter U. Fischer

Open Access Publications

No abstract provided.


Cyp2b6 Non-Coding Variation Associated With Smoking Cessation Is Also Associated With Differences In Allelic Expression, Splicing, And Nicotine Metabolism Independent Of Common Amino-Acid Changes, A. Joseph Bloom, Maribel Martinez, Li-Shiun Chen, Laura J. Bierut, Sharon E. Murphy, Alison Goate Jan 2013

Cyp2b6 Non-Coding Variation Associated With Smoking Cessation Is Also Associated With Differences In Allelic Expression, Splicing, And Nicotine Metabolism Independent Of Common Amino-Acid Changes, A. Joseph Bloom, Maribel Martinez, Li-Shiun Chen, Laura J. Bierut, Sharon E. Murphy, Alison Goate

Open Access Publications

No abstract provided.


Improved Function And Proliferation Of Adult Human Beta Cells Engrafted In Diabetic Immunodeficient Nod-Scid Il2rγ(Null) Mice Treated With Alogliptin, Agata Jurczyk, Philip Diiorio, Dean Brostowin, Linda Leehy, Chaoxing Yang, Fumihiko Urano, David M. Harlan, Leonard D. Shultz, Dale L. Greiner, Rita Bortell Jan 2013

Improved Function And Proliferation Of Adult Human Beta Cells Engrafted In Diabetic Immunodeficient Nod-Scid Il2rγ(Null) Mice Treated With Alogliptin, Agata Jurczyk, Philip Diiorio, Dean Brostowin, Linda Leehy, Chaoxing Yang, Fumihiko Urano, David M. Harlan, Leonard D. Shultz, Dale L. Greiner, Rita Bortell

Open Access Publications

No abstract provided.


Using Small-Area Analysis To Estimate County-Level Racial Disparities In Obesity Demonstrating The Necessity Of Targeted Interventions, Lucy D'Agostino-Mcgowan, Renee L. Gennarelli, Sarah A. Lyons, Melody S. Goodman Jan 2013

Using Small-Area Analysis To Estimate County-Level Racial Disparities In Obesity Demonstrating The Necessity Of Targeted Interventions, Lucy D'Agostino-Mcgowan, Renee L. Gennarelli, Sarah A. Lyons, Melody S. Goodman

Open Access Publications

No abstract provided.


Hiv-Infected Adolescent, Young Adult And Pregnant Smokers: Important Targets For Effective Tobacco Control Programs, Gerome Escota, Nur Önen Jan 2013

Hiv-Infected Adolescent, Young Adult And Pregnant Smokers: Important Targets For Effective Tobacco Control Programs, Gerome Escota, Nur Önen

Open Access Publications

No abstract provided.


Child-Oriented Marketing Techniques In Snack Food Packages In Guatemala, Violeta Chacon, Paola Letona, Joaquin Barnoya Jan 2013

Child-Oriented Marketing Techniques In Snack Food Packages In Guatemala, Violeta Chacon, Paola Letona, Joaquin Barnoya

Open Access Publications

No abstract provided.


Promoting State Health Department Evidence-Based Cancer And Chronic Disease Prevention: A Multi-Phase Dissemination Study With A Cluster Randomized Trial Component, Peg Allen, Sonia Sequeira, Rebekah R. Jacob, Adriano Akira Hino, Katherine A. Stamatakis, Jenine K. Harris, Lindsay Elliott, Jon F. Kerner, Ellen Jones, Maureen Dobbins, Elizabeth A. Baker, Ross C. Brownson Jan 2013

Promoting State Health Department Evidence-Based Cancer And Chronic Disease Prevention: A Multi-Phase Dissemination Study With A Cluster Randomized Trial Component, Peg Allen, Sonia Sequeira, Rebekah R. Jacob, Adriano Akira Hino, Katherine A. Stamatakis, Jenine K. Harris, Lindsay Elliott, Jon F. Kerner, Ellen Jones, Maureen Dobbins, Elizabeth A. Baker, Ross C. Brownson

Open Access Publications

No abstract provided.


A Proteomic Study Of Human Merkel Cell Carcinoma, Qiang Shao, Stephanie D. Byrum, Linley E. Moreland, Samuel G. Mackintosh, Aarthi Kannan, Zhenyu Lin, Michael Morgan, Brendan C. Stack Jr, Lynn A. Cornelius, Alan J. Tackett, Ling Gao Jan 2013

A Proteomic Study Of Human Merkel Cell Carcinoma, Qiang Shao, Stephanie D. Byrum, Linley E. Moreland, Samuel G. Mackintosh, Aarthi Kannan, Zhenyu Lin, Michael Morgan, Brendan C. Stack Jr, Lynn A. Cornelius, Alan J. Tackett, Ling Gao

Open Access Publications

No abstract provided.


Acute Care Costs In Overweight Children: A Pediatric Urban Cohort Study, Katherine E. Fleming-Dutra, Jingnan Mao, Julie C. Leonard Jan 2013

Acute Care Costs In Overweight Children: A Pediatric Urban Cohort Study, Katherine E. Fleming-Dutra, Jingnan Mao, Julie C. Leonard

Open Access Publications

No abstract provided.


Towards The Characterization And Validation Of Alcohol Use Disorder Subtypes: Integrating Consumption And Symptom Data, K. M. Jackson, K. K. Bucholz, P. K. Wood, D. Steinley, J. D. Grant, K. J. Sher Jan 2013

Towards The Characterization And Validation Of Alcohol Use Disorder Subtypes: Integrating Consumption And Symptom Data, K. M. Jackson, K. K. Bucholz, P. K. Wood, D. Steinley, J. D. Grant, K. J. Sher

Open Access Publications

No abstract provided.


Fecal Microbiota Diversity In Survivors Of Adolescent/Young Adult Hodgkin Lymphoma: A Study Of Twins, Wendy Cozen, Guoqin Yu, Mitchell H. Gail, Vanessa K. Ridaura, Bharat N. Nathwani, Amie E. Hwang, Ann S. Hamilton, Thomas M. Mack, Jeffrey I. Gordon, James J. Goedert Jan 2013

Fecal Microbiota Diversity In Survivors Of Adolescent/Young Adult Hodgkin Lymphoma: A Study Of Twins, Wendy Cozen, Guoqin Yu, Mitchell H. Gail, Vanessa K. Ridaura, Bharat N. Nathwani, Amie E. Hwang, Ann S. Hamilton, Thomas M. Mack, Jeffrey I. Gordon, James J. Goedert

Open Access Publications

No abstract provided.


Development Of A Modified Head And Neck Quality Assurance Phantom For Use In Stereotactic Radiosurgery Trials, Austin M. Faught, Stephen F. Kry, Dershan Luo, Andrea Molineu, David Bellezza, Russel L. Gerber, Scott E. Davidson, Walter Bosch, Robert E. Drzymala, Jim Galvin, Robert Timmerman, Jason Sheehan, Michael T. Gillin, Geoffrey S. Ibbot, David S. Followill Jan 2013

Development Of A Modified Head And Neck Quality Assurance Phantom For Use In Stereotactic Radiosurgery Trials, Austin M. Faught, Stephen F. Kry, Dershan Luo, Andrea Molineu, David Bellezza, Russel L. Gerber, Scott E. Davidson, Walter Bosch, Robert E. Drzymala, Jim Galvin, Robert Timmerman, Jason Sheehan, Michael T. Gillin, Geoffrey S. Ibbot, David S. Followill

Open Access Publications

No abstract provided.


A New Role For The Cellular Pabp Repressor Paip2 As An Innate Restriction Factor Capable Of Limiting Productive Cytomegalovirus Replication, Caleb Mckinney, Dong Yu, Ian Mohr Jan 2013

A New Role For The Cellular Pabp Repressor Paip2 As An Innate Restriction Factor Capable Of Limiting Productive Cytomegalovirus Replication, Caleb Mckinney, Dong Yu, Ian Mohr

Open Access Publications

No abstract provided.


Lagging Strand Maturation Factor Dna2 Is A Component Of The Replication Checkpoint Initiation Machinery, Sandeep Kumar, Peter M. Burgers Jan 2013

Lagging Strand Maturation Factor Dna2 Is A Component Of The Replication Checkpoint Initiation Machinery, Sandeep Kumar, Peter M. Burgers

Open Access Publications

No abstract provided.


Dna Unmethylome Profiling By Covalent Capture Of Cpg Sites, Edita Kriukienė, Viviane Labrie, Tarang Khare, Giedrė Urbanavičiūtė, Audronė Lapinaitė, Karolis Koncevičius, Daofeng Li, Ting Wang, Shraddha Pai, Carolyn Ptak, Juozas Gordevičius, Sun-Chong Wang, Artūras Petronis, Saulius Klimašauskas Jan 2013

Dna Unmethylome Profiling By Covalent Capture Of Cpg Sites, Edita Kriukienė, Viviane Labrie, Tarang Khare, Giedrė Urbanavičiūtė, Audronė Lapinaitė, Karolis Koncevičius, Daofeng Li, Ting Wang, Shraddha Pai, Carolyn Ptak, Juozas Gordevičius, Sun-Chong Wang, Artūras Petronis, Saulius Klimašauskas

Open Access Publications

No abstract provided.


Disrupting Malaria Parasite Ama1-Ron2 Interaction With A Small Molecule Prevents Erythrocyte Invasion, Prakash Srinivasan, Adam Yasgar, Diane K. Luci, Wandy L. Beatty, Xin Hu, John Andersen, David L. Narum, J. Kathleen Moch, Hongmao Sun, J. David Haynes, David J. Maloney, Ajit Jadhav, Anton Simeonov, Louis H. Miller Jan 2013

Disrupting Malaria Parasite Ama1-Ron2 Interaction With A Small Molecule Prevents Erythrocyte Invasion, Prakash Srinivasan, Adam Yasgar, Diane K. Luci, Wandy L. Beatty, Xin Hu, John Andersen, David L. Narum, J. Kathleen Moch, Hongmao Sun, J. David Haynes, David J. Maloney, Ajit Jadhav, Anton Simeonov, Louis H. Miller

Open Access Publications

No abstract provided.


Similar Effects On Cognitive Performance During High- And Low-Carbohydrate Obesity Treatment, A Makris, V L. Darcey, D L. Rosenbaum, E Komaroff, S S. Vander Veur, B N. Collins, S Klein, H R. Wyatt, G D. Foster Jan 2013

Similar Effects On Cognitive Performance During High- And Low-Carbohydrate Obesity Treatment, A Makris, V L. Darcey, D L. Rosenbaum, E Komaroff, S S. Vander Veur, B N. Collins, S Klein, H R. Wyatt, G D. Foster

Open Access Publications

No abstract provided.


Comprehensive Identification Of Mutational Cancer Driver Genes Across 12 Tumor Types, David Tamborero, Abel Gonzalez-Perez, Christian Perez-Llamas, Jordi Deu-Pons, Cyriac Kandoth, Jüri Reimand, Michael S. Lawrence, Gad Getz, Gary D. Bader, Li Ding, Nuria Lopez-Bigas Jan 2013

Comprehensive Identification Of Mutational Cancer Driver Genes Across 12 Tumor Types, David Tamborero, Abel Gonzalez-Perez, Christian Perez-Llamas, Jordi Deu-Pons, Cyriac Kandoth, Jüri Reimand, Michael S. Lawrence, Gad Getz, Gary D. Bader, Li Ding, Nuria Lopez-Bigas

Open Access Publications

No abstract provided.


Hdl And Glut1 Inhibition Reverse A Hypermetabolic State In Mouse Models Of Myeloproliferative Disorders, Emmanuel L. Gautier, Marit Westerterp, Neha Bhagwat, Serge Cremers, Alan Shih, Omar Abdel-Wahab, Dieter Lütjohann, Gwendalyn J. Randolph, Ross L. Levine, Alan R. Tall, Laurent Yvan-Charvet Jan 2013

Hdl And Glut1 Inhibition Reverse A Hypermetabolic State In Mouse Models Of Myeloproliferative Disorders, Emmanuel L. Gautier, Marit Westerterp, Neha Bhagwat, Serge Cremers, Alan Shih, Omar Abdel-Wahab, Dieter Lütjohann, Gwendalyn J. Randolph, Ross L. Levine, Alan R. Tall, Laurent Yvan-Charvet

Open Access Publications

A high metabolic rate in myeloproliferative disorders is a common complication of neoplasms, but the underlying mechanisms are incompletely understood. Using three different mouse models of myeloproliferative disorders, including mice with defective cholesterol efflux pathways and two models based on expression of human leukemia disease alleles, we uncovered a mechanism by which proliferating and inflammatory myeloid cells take up and oxidize glucose during the feeding period, contributing to energy dissipation and subsequent loss of adipose mass. In vivo, lentiviral inhibition of Glut1 by shRNA prevented myeloproliferation and adipose tissue loss in mice with defective cholesterol efflux pathway in leukocytes. Thus, …


Lncipedia: A Database For Annotated Human Lncrna Transcript Sequences And Structures, Pieter-Jan Volders, Kenny Helsens, Xiaowei Wang, Bjorn Menten, Lennart Martens, Kris Gevaert, Jo Vandesompele, Pieter Mestdagh Jan 2013

Lncipedia: A Database For Annotated Human Lncrna Transcript Sequences And Structures, Pieter-Jan Volders, Kenny Helsens, Xiaowei Wang, Bjorn Menten, Lennart Martens, Kris Gevaert, Jo Vandesompele, Pieter Mestdagh

Open Access Publications

No abstract provided.


Cd2ap Links Cortactin And Capping Protein At The Cell Periphery To Facilitate Formation Of Lamellipodia, Jianping Zhao, Serawit Bruck, Saso Cemerski, Lei Zhang, Boyd Butler, Adish Dani, John A. Cooper, Andrey S. Shaw Jan 2013

Cd2ap Links Cortactin And Capping Protein At The Cell Periphery To Facilitate Formation Of Lamellipodia, Jianping Zhao, Serawit Bruck, Saso Cemerski, Lei Zhang, Boyd Butler, Adish Dani, John A. Cooper, Andrey S. Shaw

Open Access Publications

Understanding the physiology of complex relationships between components of signaling pathways and the actin cytoskeleton is an important challenge. CD2AP is a membrane scaffold protein implicated in a variety of physiological and disease processes. The physiological function of CD2AP is unclear, but its biochemical interactions suggest that it has a role in dynamic actin assembly. Here, we report that CD2AP functions to facilitate the recruitment of actin capping protein (CP) to the Src kinase substrate, cortactin, at the cell periphery, and that this is necessary for formation of the short branched filaments that characterize lamellipodium formation and are required for …


Investigation Of Neovascularization In Three-Dimensional Porous Scaffolds In Vivo By A Combination Of Multiscale Photoacoustic Microscopy And Optical Coherence Tomography, Xin Cai, Yu Zhang, Li Li, Sung-Wook Choi, Matthew R. Macewan, Junjie Yao, Chulhong Kim, Younan Xia, Lihong V. Wang Jan 2013

Investigation Of Neovascularization In Three-Dimensional Porous Scaffolds In Vivo By A Combination Of Multiscale Photoacoustic Microscopy And Optical Coherence Tomography, Xin Cai, Yu Zhang, Li Li, Sung-Wook Choi, Matthew R. Macewan, Junjie Yao, Chulhong Kim, Younan Xia, Lihong V. Wang

Open Access Publications

No abstract provided.


Gene-Alcohol Interactions Identify Several Novel Blood Pressure Loci Including A Promising Locus Near Slc16a9, Jeannette Simino, Yun Ju Sung, Rezart Kume, Karen Schwander, D. C. Rao Jan 2013

Gene-Alcohol Interactions Identify Several Novel Blood Pressure Loci Including A Promising Locus Near Slc16a9, Jeannette Simino, Yun Ju Sung, Rezart Kume, Karen Schwander, D. C. Rao

Open Access Publications

No abstract provided.


A Comprehensive Promoter Landscape Identifies A Novel Promoter For Cd133 In Restricted Tissues, Cancers, And Stem Cells, Ramakrishna Sompallae, Oliver Hofmann, Christopher A. Maher, Craig Gedye, Andreas Behren, Morana Vitezic, Carsten O. Daub, Sylvie Devalle, Octavia L. Caballero, Piero Carninci, Yoshihide Hayashizaki, Elizabeth R. Lawlor, Jonathan Cebon, Winston Hide Jan 2013

A Comprehensive Promoter Landscape Identifies A Novel Promoter For Cd133 In Restricted Tissues, Cancers, And Stem Cells, Ramakrishna Sompallae, Oliver Hofmann, Christopher A. Maher, Craig Gedye, Andreas Behren, Morana Vitezic, Carsten O. Daub, Sylvie Devalle, Octavia L. Caballero, Piero Carninci, Yoshihide Hayashizaki, Elizabeth R. Lawlor, Jonathan Cebon, Winston Hide

Open Access Publications

No abstract provided.


Genome-Wide Association Study Of Personality Traits In The Long Life Family Study, Harold T. Bae, Paola Sebastiani, Jenny X. Sun, Stacy L. Andersen, E. Warwick Daw, Antonio Terracciano, Luigi Ferrucci, Thomas T. Perls Jan 2013

Genome-Wide Association Study Of Personality Traits In The Long Life Family Study, Harold T. Bae, Paola Sebastiani, Jenny X. Sun, Stacy L. Andersen, E. Warwick Daw, Antonio Terracciano, Luigi Ferrucci, Thomas T. Perls

Open Access Publications

No abstract provided.


Dna Polymerase Δ Stalls On Telomeric Lagging Strand Templates Independently From G-Quadruplex Formation, Justin D. Lormand, Noah Buncher, Connor T. Murphy, Parminder Kaur, Marietta Y. Lee, Peter Burgers, Hong Wang, Thomas A. Kunkel, Patricia L. Opresko Jan 2013

Dna Polymerase Δ Stalls On Telomeric Lagging Strand Templates Independently From G-Quadruplex Formation, Justin D. Lormand, Noah Buncher, Connor T. Murphy, Parminder Kaur, Marietta Y. Lee, Peter Burgers, Hong Wang, Thomas A. Kunkel, Patricia L. Opresko

Open Access Publications

No abstract provided.


Epigenetic Activation And Silencing Of The Gene That Encodes Ifn-Γ, Thomas M. Aune, Patrick L. Collins, Sarah P. Collier, Melodie A. Henderson, Shaojing Chang Jan 2013

Epigenetic Activation And Silencing Of The Gene That Encodes Ifn-Γ, Thomas M. Aune, Patrick L. Collins, Sarah P. Collier, Melodie A. Henderson, Shaojing Chang

Open Access Publications

No abstract provided.


Distinct Neural Signatures Detected For Adhd Subtypes After Controlling For Micro-Movements In Resting State Functional Connectivity Mri Data, Nico U.F. Dosenbach, Bradley L. Schlaggar, Et Al Jan 2013

Distinct Neural Signatures Detected For Adhd Subtypes After Controlling For Micro-Movements In Resting State Functional Connectivity Mri Data, Nico U.F. Dosenbach, Bradley L. Schlaggar, Et Al

Open Access Publications

No abstract provided.