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Articles 3751 - 3780 of 4253
Full-Text Articles in Entire DC Network
Improving Gene-Finding In Chlamydomonas Reinhardtii: Greengenie2, Alan L. Kwan, Linya Li, David C. Kulp, Susan K. Dutcher, Gary D. Stormo
Improving Gene-Finding In Chlamydomonas Reinhardtii: Greengenie2, Alan L. Kwan, Linya Li, David C. Kulp, Susan K. Dutcher, Gary D. Stormo
Open Access Publications
No abstract provided.
The Value Of Avian Genomics To The Conservation Of Wildlife, Michael N. Romanov, Elaina M. Tuttle, Marlys L. Houck, William S. Modi, Leona G. Chemnick, Marisa L. Korody, Emily M. Stremel Mork, Christie A. Otten, Tanya Renner, Kenneth C. Jones, Sugandha Dandekar, Jeanette C. Papp, Yang Da, Nisc Comparative Sequencing Program, Eric D. Green, Vincent Magrini, Matthew T. Hickenbotham, Jarret Glasscock, Sean Mcgrath, Elaine R. Mardis, Oliver A. Ryder
The Value Of Avian Genomics To The Conservation Of Wildlife, Michael N. Romanov, Elaina M. Tuttle, Marlys L. Houck, William S. Modi, Leona G. Chemnick, Marisa L. Korody, Emily M. Stremel Mork, Christie A. Otten, Tanya Renner, Kenneth C. Jones, Sugandha Dandekar, Jeanette C. Papp, Yang Da, Nisc Comparative Sequencing Program, Eric D. Green, Vincent Magrini, Matthew T. Hickenbotham, Jarret Glasscock, Sean Mcgrath, Elaine R. Mardis, Oliver A. Ryder
Open Access Publications
No abstract provided.
Mice Lacking Mannose 6-Phosphate Uncovering Enzyme Activity Have A Milder Phenotype Than Mice Deficient For N-Acetylglucosamine-1-Phosphotransferase Activity, Marielle Boonen, Peter Vogel, Kenneth A. Platt, Nancy Dahms, Stuart Kornfeld
Mice Lacking Mannose 6-Phosphate Uncovering Enzyme Activity Have A Milder Phenotype Than Mice Deficient For N-Acetylglucosamine-1-Phosphotransferase Activity, Marielle Boonen, Peter Vogel, Kenneth A. Platt, Nancy Dahms, Stuart Kornfeld
Open Access Publications
No abstract provided.
Lull1 Retargets Torsina To The Nuclear Envelope Revealing An Activity That Is Impaired By The Dyt1 Dystonia Mutation, Abigail B. Vander Heyden, Teresa V. Naismith, Erik L. Snapp, Didier Hodzic, Phyllis I. Hanson
Lull1 Retargets Torsina To The Nuclear Envelope Revealing An Activity That Is Impaired By The Dyt1 Dystonia Mutation, Abigail B. Vander Heyden, Teresa V. Naismith, Erik L. Snapp, Didier Hodzic, Phyllis I. Hanson
Open Access Publications
No abstract provided.
Histone H2ax Stabilizes Broken Dna Strands To Suppress Chromosome Breaks And Translocations During V(D)J Recombination, Bu Yin, Velibor Savic, Marisa M. Juntilla, Andrea L. Bredemeyer, Katherine S. Yang-Iott, Beth A. Helmink, Gary A. Koretzky, Barry P. Sleckman, Craig H. Bassing
Histone H2ax Stabilizes Broken Dna Strands To Suppress Chromosome Breaks And Translocations During V(D)J Recombination, Bu Yin, Velibor Savic, Marisa M. Juntilla, Andrea L. Bredemeyer, Katherine S. Yang-Iott, Beth A. Helmink, Gary A. Koretzky, Barry P. Sleckman, Craig H. Bassing
Open Access Publications
No abstract provided.
Pathogenicity Of A Disease-Associated Human Il-4 Receptor Allele In Experimental Asthma, Raffi Tachdjian, Clinton Mathias, Shadi Al Khatib, Paul J. Bryce, Hong S. Kim, Frank Blaeser, Brian D. O'Connor, Danuta Rzymkiewicz, Andrew Chen, Michael J. Holtzman, Gurjit K. Hershey, Holger Garn, Hani Harb, Harald Renz, Hans C. Oettgen, Talal A. Chatila
Pathogenicity Of A Disease-Associated Human Il-4 Receptor Allele In Experimental Asthma, Raffi Tachdjian, Clinton Mathias, Shadi Al Khatib, Paul J. Bryce, Hong S. Kim, Frank Blaeser, Brian D. O'Connor, Danuta Rzymkiewicz, Andrew Chen, Michael J. Holtzman, Gurjit K. Hershey, Holger Garn, Hani Harb, Harald Renz, Hans C. Oettgen, Talal A. Chatila
Open Access Publications
No abstract provided.
Chitinases Are Essential For Sexual Development But Not Vegetative Growth In Cryptococcus Neoformans, Lorina G. Baker, Charles A. Sprecht, Jennifer K. Lodge
Chitinases Are Essential For Sexual Development But Not Vegetative Growth In Cryptococcus Neoformans, Lorina G. Baker, Charles A. Sprecht, Jennifer K. Lodge
Open Access Publications
No abstract provided.
Detection And Characterization Of The Fimbrial Sfp Cluster In Enterohemorrhagic Escherichia Coli O165:H25/Nm Isolates From Humans And Cattle, Martina Bielaszewska, Rita Prager, Liz Vandivinit, Anne Musken, Alexander Mellmann, Nicholas J. Holt, Phillip I. Tarr, Helge Karch, Wenlan Zhang
Detection And Characterization Of The Fimbrial Sfp Cluster In Enterohemorrhagic Escherichia Coli O165:H25/Nm Isolates From Humans And Cattle, Martina Bielaszewska, Rita Prager, Liz Vandivinit, Anne Musken, Alexander Mellmann, Nicholas J. Holt, Phillip I. Tarr, Helge Karch, Wenlan Zhang
Open Access Publications
No abstract provided.
Chemosensitizing And Cytotoxic Effects Of 2-Deoxy-D-Glucose On Breast Cancer Cells, Fanjie Zhang, Rebecca L. Aft
Chemosensitizing And Cytotoxic Effects Of 2-Deoxy-D-Glucose On Breast Cancer Cells, Fanjie Zhang, Rebecca L. Aft
Open Access Publications
No abstract provided.
Virus And Host Determinants Of West Nile Virus Pathogenesis, Michael S. Diamond
Virus And Host Determinants Of West Nile Virus Pathogenesis, Michael S. Diamond
Open Access Publications
No abstract provided.
Comparative Effects Of Heterologous Trpv1 And Trpm8 Expression In Rat Hippocampal Neurons, Devon C. Crawford, Krista L. Moulder, Robert W. Gereau Iv, Gina M. Story, Steven Mennerick
Comparative Effects Of Heterologous Trpv1 And Trpm8 Expression In Rat Hippocampal Neurons, Devon C. Crawford, Krista L. Moulder, Robert W. Gereau Iv, Gina M. Story, Steven Mennerick
Open Access Publications
No abstract provided.
Induction Of Ifn-Beta And The Innate Antiviral Response In Myeloid Cells Occurs Through An Ips-1-Dependent Signal That Does Not Require Irf-3 And Irf-7, Stephane Daffis, Mehul S. Suthar, Kristy J. Szretter, Michael Gale Jr., Michael S. Diamond
Induction Of Ifn-Beta And The Innate Antiviral Response In Myeloid Cells Occurs Through An Ips-1-Dependent Signal That Does Not Require Irf-3 And Irf-7, Stephane Daffis, Mehul S. Suthar, Kristy J. Szretter, Michael Gale Jr., Michael S. Diamond
Open Access Publications
No abstract provided.
Chronic Cyclodextrin Treatment Of Murine Niemann-Pick C Disease Ameliorates Neuronal Cholesterol And Glycosphingolipid Storage And Disease Progression, Cristin D. Davidson, Nafeeza F. Ali, Mathew C. Micsenyi, Gloria Stephney, Sophie Renault, Kostantin Dobrenis, Daniel S. Ory, Marie T. Vanier, Steven U. Walkley
Chronic Cyclodextrin Treatment Of Murine Niemann-Pick C Disease Ameliorates Neuronal Cholesterol And Glycosphingolipid Storage And Disease Progression, Cristin D. Davidson, Nafeeza F. Ali, Mathew C. Micsenyi, Gloria Stephney, Sophie Renault, Kostantin Dobrenis, Daniel S. Ory, Marie T. Vanier, Steven U. Walkley
Open Access Publications
No abstract provided.
The Effects Of Tail Biopsy For Genotyping On Behavioral Responses To Nociceptive Stimuli, Maria Elena P. Morales, Robert W. Gereau Iv
The Effects Of Tail Biopsy For Genotyping On Behavioral Responses To Nociceptive Stimuli, Maria Elena P. Morales, Robert W. Gereau Iv
Open Access Publications
No abstract provided.
Dosage Effects Of Cohesin Regulatory Factor Pds5 On Mammalian Development: Implications For Cohesinopathies, Bin Zhang, Jufang Chang, Ming Fu, Jie Huang, Rakesh Kashyap, Ezequiel Salavaggione, Sanjay Jain, Kulkarni Shashikant, Matthew A. Deardorff, Maria L. Giovannucci Uzielli, Dale Dorsett, David C. Beebe, Patrick Y. Jay, Robert O. Heuckeroth, Ian Krantz, Jeffrey Milbrandt
Dosage Effects Of Cohesin Regulatory Factor Pds5 On Mammalian Development: Implications For Cohesinopathies, Bin Zhang, Jufang Chang, Ming Fu, Jie Huang, Rakesh Kashyap, Ezequiel Salavaggione, Sanjay Jain, Kulkarni Shashikant, Matthew A. Deardorff, Maria L. Giovannucci Uzielli, Dale Dorsett, David C. Beebe, Patrick Y. Jay, Robert O. Heuckeroth, Ian Krantz, Jeffrey Milbrandt
Open Access Publications
No abstract provided.
Functional Brain Networks Develop From A ‘‘Local To Distributed’’ Organization, Damian A. Fair, Alexander L. Cohen, Jonathan D. Power, Nico U. F. Dosenbach, Jessica A. Church, Fancis M. Miezin, Bradley L. Schlaggar, Steven E. Petersen
Functional Brain Networks Develop From A ‘‘Local To Distributed’’ Organization, Damian A. Fair, Alexander L. Cohen, Jonathan D. Power, Nico U. F. Dosenbach, Jessica A. Church, Fancis M. Miezin, Bradley L. Schlaggar, Steven E. Petersen
Open Access Publications
No abstract provided.
Helminth Genomics: The Implications For Human Health, Paul J. Brindley, Makedonka Mitreva, Elodie Ghedin, Sara Lustigman
Helminth Genomics: The Implications For Human Health, Paul J. Brindley, Makedonka Mitreva, Elodie Ghedin, Sara Lustigman
Open Access Publications
No abstract provided.
Degradation Of Host Sphingomyelin Is Essential For Leishmania Virulence, Ou Zhang, Mattie C. Wilson, Wei Xu, Fong-Fu Hsu, John Turk, F. Matthew Kuhlmann, Yingwei Wang, Lynn Soong, Phillip Key, Stephen M. Beverley, Kai Zhang
Degradation Of Host Sphingomyelin Is Essential For Leishmania Virulence, Ou Zhang, Mattie C. Wilson, Wei Xu, Fong-Fu Hsu, John Turk, F. Matthew Kuhlmann, Yingwei Wang, Lynn Soong, Phillip Key, Stephen M. Beverley, Kai Zhang
Open Access Publications
No abstract provided.
Selection At A Single Locus Leads To Widespread Expansion Of Toxoplasma Gondii Lineages That Are Virulent In Mice, Asis Khan, Sonya Taylor, James W. Ajioka, Benjamin M. Rosenthal, L. David Sibley
Selection At A Single Locus Leads To Widespread Expansion Of Toxoplasma Gondii Lineages That Are Virulent In Mice, Asis Khan, Sonya Taylor, James W. Ajioka, Benjamin M. Rosenthal, L. David Sibley
Open Access Publications
No abstract provided.
A Role Of Scn9a In Human Epilepsies, As A Cause Of Febrile Seizures And As A Potential Modifier Of Dravet Syndrome, Nanda A. Singh, Chris Pappas, E. Jill Dahle, Lieve R. F. Claes, Timothy H. Pruess, Peter De Jonghe, Joel Thompson, Missy Dixon, Christina Gurnett, Andy Peiffer, H. Steve White, Francis Filloux, Mark F. Leppert
A Role Of Scn9a In Human Epilepsies, As A Cause Of Febrile Seizures And As A Potential Modifier Of Dravet Syndrome, Nanda A. Singh, Chris Pappas, E. Jill Dahle, Lieve R. F. Claes, Timothy H. Pruess, Peter De Jonghe, Joel Thompson, Missy Dixon, Christina Gurnett, Andy Peiffer, H. Steve White, Francis Filloux, Mark F. Leppert
Open Access Publications
No abstract provided.
In Vitro Growth Environment Produces Lipidomic And Electron Transport Chain Abnormalities In Mitochondria From Nontumorigenic Astrocytes And Brain Tumours, Michael A. Kiebish, Xianlin Han, Hua Cheng, Thomas N. Seyfried
In Vitro Growth Environment Produces Lipidomic And Electron Transport Chain Abnormalities In Mitochondria From Nontumorigenic Astrocytes And Brain Tumours, Michael A. Kiebish, Xianlin Han, Hua Cheng, Thomas N. Seyfried
Open Access Publications
No abstract provided.
Bringing Kash Under The Sun: The Many Faces Of Nucleo-Cytoskeletal Connections, David Razafsky, Didier Hodzic
Bringing Kash Under The Sun: The Many Faces Of Nucleo-Cytoskeletal Connections, David Razafsky, Didier Hodzic
Open Access Publications
No abstract provided.
Evidence For High Bi-Allelic Expression Of Activating Ly49 Receptors, Arefeh Rouhi, C. B. Lai, Tammy P. Cheng, Fumio Takei, Wayne M. Yokoyama, Dixie L. Mager
Evidence For High Bi-Allelic Expression Of Activating Ly49 Receptors, Arefeh Rouhi, C. B. Lai, Tammy P. Cheng, Fumio Takei, Wayne M. Yokoyama, Dixie L. Mager
Open Access Publications
No abstract provided.
Nematode.Net Update 2008: Improvements Enabling More Efficient Data Mining And Comparative Nematode Genomics, John Martin, Sahar Abubucker, Todd Wylie, Yong Yin, Zhengyuan Wang, Makedonka Mitreva
Nematode.Net Update 2008: Improvements Enabling More Efficient Data Mining And Comparative Nematode Genomics, John Martin, Sahar Abubucker, Todd Wylie, Yong Yin, Zhengyuan Wang, Makedonka Mitreva
Open Access Publications
No abstract provided.
Key Role Of T Cell Defects In Age-Related Vulnerability To West Nile Virus, James D. Brien, Jennifer L. Uhrlaub, Alec Hirsch, Clayton A. Wiley, Janko Nikolich-Zugich
Key Role Of T Cell Defects In Age-Related Vulnerability To West Nile Virus, James D. Brien, Jennifer L. Uhrlaub, Alec Hirsch, Clayton A. Wiley, Janko Nikolich-Zugich
Open Access Publications
West Nile virus (WNV) infection causes a life-threatening meningoencephalitis that becomes increasingly more prevalent over the age of 50 and is 40-50x more prevalent in people over the age of 70, compared with adults under the age of 40. In a mouse model of age-related vulnerability to WNV, we demonstrate that death correlates with increased viral titers in the brain and that this loss of virus control with age was the result of defects in the CD4 and CD8 T cell response against WNV. Specific age-related defects in T cell responses against dominant WNV epitopes were detected at the level …
Trem-2 (Triggering Receptor Expressed On Myeloid Cells 2) Is A Phagocytic Receptor For Bacteria, Elsa-Noah N'Diaye, Catherine S. Branda, Steven S. Branda, Lisette Nevarez, Marco Colonna, Clifford Lowell, Jessica A. Hamerman, William E. Seaman
Trem-2 (Triggering Receptor Expressed On Myeloid Cells 2) Is A Phagocytic Receptor For Bacteria, Elsa-Noah N'Diaye, Catherine S. Branda, Steven S. Branda, Lisette Nevarez, Marco Colonna, Clifford Lowell, Jessica A. Hamerman, William E. Seaman
Open Access Publications
Phagocytosis, which is essential for the immune response to pathogens, is initiated by specific interactions between pathogens and cell surface receptors expressed by phagocytes. This study identifies triggering receptor expressed on myeloid cells 2 (TREM-2) and its signaling counterpart DAP12 as a molecular complex that promotes phagocytosis of bacteria. Expression of TREM-2-DAP12 enables nonphagocytic Chinese hamster ovary cells to internalize bacteria. This function depends on actin cytoskeleton dynamics and the activity of the small guanosine triphosphatases Rac and Cdc42. Internalization also requires src kinase activity and tyrosine phosphorylation. In bone marrow-derived macrophages, phagocytosis is decreased in the absence of DAP12 …
Cdc42 Antagonizes Rho1 Activity At Adherens Junctions To Limit Epithelial Cell Apical Tension, Stephen J. Warner, Gregory D. Longmore
Cdc42 Antagonizes Rho1 Activity At Adherens Junctions To Limit Epithelial Cell Apical Tension, Stephen J. Warner, Gregory D. Longmore
Open Access Publications
In epithelia, cells are arranged in an orderly pattern with a defined orientation and shape. Cadherin containing apical adherens junctions (AJs) and the associated actomyosin cytoskeleton likely contribute to epithelial cell shape by providing apical tension. The Rho guanosine triphosphatases are well known regulators of cell junction formation, maintenance, and function. Specifically, Rho promotes actomyosin activity and cell contractility; however, what controls and localizes this Rho activity as epithelia remodel is unresolved. Using mosaic clonal analysis in the Drosophila melanogaster pupal eye, we find that Cdc42 is critical for limiting apical cell tension by antagonizing Rho activity at AJs. Cdc42 …
Impact Speed Does Not Determine Severity Of Spinal Cord Injury In Mice With Fixed Impact Displacement, Joong Hee Kim, Tsang-Wei Tu, Philip V. Bayly, Sheng-Kwei Song
Impact Speed Does Not Determine Severity Of Spinal Cord Injury In Mice With Fixed Impact Displacement, Joong Hee Kim, Tsang-Wei Tu, Philip V. Bayly, Sheng-Kwei Song
Open Access Publications
No abstract provided.
A Proposal For A Coordinated Effort For The Determination Of Brainwide Neuroanatomical Connectivity In Model Organisms At A Mesoscopic Scale, Joseph L. Price, David C. Van Essen, Et Al.
A Proposal For A Coordinated Effort For The Determination Of Brainwide Neuroanatomical Connectivity In Model Organisms At A Mesoscopic Scale, Joseph L. Price, David C. Van Essen, Et Al.
Open Access Publications
No abstract provided.
Identification Of Atg5-Dependent Transcriptional Changes And Increases In Mitochondrial Mass In Atg5-Deficient T Lymphocytes, Linda M. Stephenson, Brian C. Miller, Aylwin Ng, Jason Eisenberg, Zijiang Zhao, Ken Cadwell, Daniel B. Graham, Noboru N. Mizushima, Ramnik Xavier, Herbert W. Virgin, Wojciech Swat
Identification Of Atg5-Dependent Transcriptional Changes And Increases In Mitochondrial Mass In Atg5-Deficient T Lymphocytes, Linda M. Stephenson, Brian C. Miller, Aylwin Ng, Jason Eisenberg, Zijiang Zhao, Ken Cadwell, Daniel B. Graham, Noboru N. Mizushima, Ramnik Xavier, Herbert W. Virgin, Wojciech Swat
Open Access Publications
No abstract provided.