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Articles 1951 - 1980 of 4253
Full-Text Articles in Entire DC Network
Structured Illumination Diffuse Optical Tomography For Noninvasive Functional Neuroimaging In Mice, Matthew D. Reisman, Zachary E. Markow, Adam Q. Bauer, Joseph P. Culver
Structured Illumination Diffuse Optical Tomography For Noninvasive Functional Neuroimaging In Mice, Matthew D. Reisman, Zachary E. Markow, Adam Q. Bauer, Joseph P. Culver
Open Access Publications
No abstract provided.
Mapping Effective Connectivity Within Cortical Networks With Diffuse Optical Tomography, Mahlega S. Hassanpour, Adam T. Eggebrecht, Jonathan E. Peelle, Joseph P. Culver
Mapping Effective Connectivity Within Cortical Networks With Diffuse Optical Tomography, Mahlega S. Hassanpour, Adam T. Eggebrecht, Jonathan E. Peelle, Joseph P. Culver
Open Access Publications
No abstract provided.
Recombinant Adeno-Associated Viral Integration And Genotoxicity: Insights From Animal Models, Randy J. Chandler, Mark S. Sands, Charles P. Venditti
Recombinant Adeno-Associated Viral Integration And Genotoxicity: Insights From Animal Models, Randy J. Chandler, Mark S. Sands, Charles P. Venditti
Open Access Publications
No abstract provided.
Modeling The Kinetics Of Serum Glial Fibrillary Acidic Protein, Ubiquitin Carboxyl-Terminal Hydrolase-L1, And S100b Concentrations In Patients With Traumatic Brain Injury, Robert D. Welch, Morgan Ellis, Lawrence M. Lewis, Syed I. Ayez, Valerie H. Mika, Scott Millis, Linda Papa
Modeling The Kinetics Of Serum Glial Fibrillary Acidic Protein, Ubiquitin Carboxyl-Terminal Hydrolase-L1, And S100b Concentrations In Patients With Traumatic Brain Injury, Robert D. Welch, Morgan Ellis, Lawrence M. Lewis, Syed I. Ayez, Valerie H. Mika, Scott Millis, Linda Papa
Open Access Publications
No abstract provided.
Microglial Complement Receptor 3 Regulates Brain Aβ Levels Through Secreted Proteolytic Activity, Eva Czirr, John R. Cirrito, Et Al
Microglial Complement Receptor 3 Regulates Brain Aβ Levels Through Secreted Proteolytic Activity, Eva Czirr, John R. Cirrito, Et Al
Open Access Publications
No abstract provided.
Aav-Mediated Expression Of Anti-Tau Scfvs Decreases Tau Accumulation In A Mouse Model Of Tauopathy, Christina Ising, Gilbert Gallardo, Cheryl E.G. Leyns, Connie H. Wong, Hong Jiang, Floy Stewart, Lauren J. Koscal, Joseph Roh, Grace O. Robinson, Javier Remolina Serrano, David M. Holtzman
Aav-Mediated Expression Of Anti-Tau Scfvs Decreases Tau Accumulation In A Mouse Model Of Tauopathy, Christina Ising, Gilbert Gallardo, Cheryl E.G. Leyns, Connie H. Wong, Hong Jiang, Floy Stewart, Lauren J. Koscal, Joseph Roh, Grace O. Robinson, Javier Remolina Serrano, David M. Holtzman
Open Access Publications
Tauopathies are characterized by the progressive accumulation of hyperphosphorylated, aggregated forms of tau. Our laboratory has previously demonstrated that passive immunization with an anti-tau antibody, HJ8.5, decreased accumulation of pathological tau in a human P301S tau-expressing transgenic (P301S-tg) mouse model of frontotemporal dementia/tauopathy. To investigate whether the F
Multimodal Fluorescence Molecular Imaging For In Vivo Characterization Of Skin Cancer Using Endogenous And Exogenous Fluorophores, Jessica P. Miller, Lemoyne Habimana-Griffin, Tracy S. Edwards, Samuel Achilefu
Multimodal Fluorescence Molecular Imaging For In Vivo Characterization Of Skin Cancer Using Endogenous And Exogenous Fluorophores, Jessica P. Miller, Lemoyne Habimana-Griffin, Tracy S. Edwards, Samuel Achilefu
Open Access Publications
No abstract provided.
A 3-Way Hybrid Approach To Generate A New High-Quality Chimpanzee Reference Genome (Pan_Tro_3.0), Chad Tomlinson, Ladeana W. Hillier, Wesley C. Warren, Et Al
A 3-Way Hybrid Approach To Generate A New High-Quality Chimpanzee Reference Genome (Pan_Tro_3.0), Chad Tomlinson, Ladeana W. Hillier, Wesley C. Warren, Et Al
Open Access Publications
No abstract provided.
Downregulation Of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose–Induced Apoptosis, Dongjoon Kim, Robert P. Mecham, Philip C. Trackman, Sayon Roy
Downregulation Of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose–Induced Apoptosis, Dongjoon Kim, Robert P. Mecham, Philip C. Trackman, Sayon Roy
Open Access Publications
No abstract provided.
Effects Of Vitrectomy And Lensectomy On Older Rhesus Macaques: Oxygen Distribution, Antioxidant Status, And Aqueous Humor Dynamics, Carla J. Siegried, Ying-Bo Shui, Baohe Tian, Michael Nork, Gregg A. Heatley, Paul L. Kaufman
Effects Of Vitrectomy And Lensectomy On Older Rhesus Macaques: Oxygen Distribution, Antioxidant Status, And Aqueous Humor Dynamics, Carla J. Siegried, Ying-Bo Shui, Baohe Tian, Michael Nork, Gregg A. Heatley, Paul L. Kaufman
Open Access Publications
No abstract provided.
Fibroblast Growth Factor Receptor 2 (Fgfr2) Is Required For Meibomian Gland Homeostasis In The Adult Mouse, Lixing W. Reneker, Lanlan Wang, Rebecca T. Irlmeier, Andrew J. W. Huang
Fibroblast Growth Factor Receptor 2 (Fgfr2) Is Required For Meibomian Gland Homeostasis In The Adult Mouse, Lixing W. Reneker, Lanlan Wang, Rebecca T. Irlmeier, Andrew J. W. Huang
Open Access Publications
No abstract provided.
Crx-L253x Mutation Produces Dominant Photoreceptor Defects In Tvrm65 Mice, Philip A. Ruzycki, Courtney D. Linne, Anne K. Hennig, Shiming Chen
Crx-L253x Mutation Produces Dominant Photoreceptor Defects In Tvrm65 Mice, Philip A. Ruzycki, Courtney D. Linne, Anne K. Hennig, Shiming Chen
Open Access Publications
No abstract provided.
Alu Insertion Polymorphisms As Evidence For Population Structure In Baboons, Cody J. Steely, Jane Phillips-Conroy, Et Al
Alu Insertion Polymorphisms As Evidence For Population Structure In Baboons, Cody J. Steely, Jane Phillips-Conroy, Et Al
Open Access Publications
No abstract provided.
Rehabilitation Research At The National Institutes Of Health: Moving The Field Forward (Executive Summary), Walter R. Frontera, Jonathan F. Bean, Diane Damiano, Linda Ehrlich-Jones, Melanie Fried-Oken, Alan Jette, Ranu Jung, Rick L. Lieber, James F. Malec, Michael J. Mueller, Kenneth J. Ottenbacher, Keith E. Tansey, Aiko Thompson
Rehabilitation Research At The National Institutes Of Health: Moving The Field Forward (Executive Summary), Walter R. Frontera, Jonathan F. Bean, Diane Damiano, Linda Ehrlich-Jones, Melanie Fried-Oken, Alan Jette, Ranu Jung, Rick L. Lieber, James F. Malec, Michael J. Mueller, Kenneth J. Ottenbacher, Keith E. Tansey, Aiko Thompson
Open Access Publications
No abstract provided.
Diabetes Induced By Gain-Of-Function Mutations In The Kir6.1 Subunit Of The Katp Channel, Maria S. Remedi, Jonathan B. Friedman, Colin G. Nichols
Diabetes Induced By Gain-Of-Function Mutations In The Kir6.1 Subunit Of The Katp Channel, Maria S. Remedi, Jonathan B. Friedman, Colin G. Nichols
Open Access Publications
No abstract provided.
Expression Of Ifnlr1 On Intestinal Epithelial Cells Is Critical To The Antiviral Effects Of Ifn-Lambda Against Norovirus And Reovirus, Megan T. Baldridge, Sanghyun Lee, Judy J. Brown, Nicole Mcallister, Kelly Urbanek, Terence S. Dermody, Timothy J. Nice, Herbert W. Virgin
Expression Of Ifnlr1 On Intestinal Epithelial Cells Is Critical To The Antiviral Effects Of Ifn-Lambda Against Norovirus And Reovirus, Megan T. Baldridge, Sanghyun Lee, Judy J. Brown, Nicole Mcallister, Kelly Urbanek, Terence S. Dermody, Timothy J. Nice, Herbert W. Virgin
Open Access Publications
No abstract provided.
Changes Of Ovarian Microrna Profile In Long-Living Ames Dwarf Mice During Aging, Augusto Schneider, Scot J. Matkovich, Berta Victoria, Lina Spinel, Andrzsj Bartke, Pawel Golusinski, Michal M. Masternak
Changes Of Ovarian Microrna Profile In Long-Living Ames Dwarf Mice During Aging, Augusto Schneider, Scot J. Matkovich, Berta Victoria, Lina Spinel, Andrzsj Bartke, Pawel Golusinski, Michal M. Masternak
Open Access Publications
No abstract provided.
Continuing Medical Education Speakers With High Evaluation Scores Use More Image-Based Slides, Ian Ferguson, Andrew W. Phillips, Michelle Lin
Continuing Medical Education Speakers With High Evaluation Scores Use More Image-Based Slides, Ian Ferguson, Andrew W. Phillips, Michelle Lin
Open Access Publications
No abstract provided.
Brain Microvasculature Defects And Glut1 Deficiency Syndrome Averted By Early Repletion Of The Glucose Transporter-1 Protein, Lynne Jones, Et Al
Brain Microvasculature Defects And Glut1 Deficiency Syndrome Averted By Early Repletion Of The Glucose Transporter-1 Protein, Lynne Jones, Et Al
Open Access Publications
No abstract provided.
Rapid Generation Of Hypomorphic Mutations, Laura L. Arthur, Joyce J. Chung, Preetam Jankirama, Kathryn M. Keefer, Igor Kolotilin, Slavica Pavlovic-Djuranovic, Douglas L. Chalker, Vojislava Grbic, Rachel Green, Rima Menassa, Heather L. True, James B. Skeath, Sergej Djuranovic
Rapid Generation Of Hypomorphic Mutations, Laura L. Arthur, Joyce J. Chung, Preetam Jankirama, Kathryn M. Keefer, Igor Kolotilin, Slavica Pavlovic-Djuranovic, Douglas L. Chalker, Vojislava Grbic, Rachel Green, Rima Menassa, Heather L. True, James B. Skeath, Sergej Djuranovic
Open Access Publications
No abstract provided.
Apoe Genotype Differentially Modulates Effects Of Anti-Aβ, Passive Immunization In App Transgenic Mice, Joanna E. Pankiewicz, Jairo Baquero-Buitrago, Sandrine Sanchez, Jennifer Lopez-Contreras, Jungsu Kim, Patrick M. Sullivan, David M. Holtman, Martin J. Sadowski
Apoe Genotype Differentially Modulates Effects Of Anti-Aβ, Passive Immunization In App Transgenic Mice, Joanna E. Pankiewicz, Jairo Baquero-Buitrago, Sandrine Sanchez, Jennifer Lopez-Contreras, Jungsu Kim, Patrick M. Sullivan, David M. Holtman, Martin J. Sadowski
Open Access Publications
No abstract provided.
Novel Treatment Of Chronic Graft-Versus-Host Disease In Mice Using The Er Stress Reducer 4-Phenylbutyric Acid, Shin Mukai, Yoko Ogawa, Fumihiko Urano, Chie Kudo-Saito, Yutaka Kawakami, Kazuo Tsubota
Novel Treatment Of Chronic Graft-Versus-Host Disease In Mice Using The Er Stress Reducer 4-Phenylbutyric Acid, Shin Mukai, Yoko Ogawa, Fumihiko Urano, Chie Kudo-Saito, Yutaka Kawakami, Kazuo Tsubota
Open Access Publications
No abstract provided.
Knockout Of Lysosomal Enzyme-Targeting Gene Causes Abnormalities In Mouse Pup Isolation Calls, Terra D. Barnes, Timothy E. Holy
Knockout Of Lysosomal Enzyme-Targeting Gene Causes Abnormalities In Mouse Pup Isolation Calls, Terra D. Barnes, Timothy E. Holy
Open Access Publications
No abstract provided.
Animal Models Of Zika Virus Infection, Pathogenesis, And Immunity, Thomas E. Morrison, Michael S. Diamond
Animal Models Of Zika Virus Infection, Pathogenesis, And Immunity, Thomas E. Morrison, Michael S. Diamond
Open Access Publications
No abstract provided.
Exacerbated Leishmaniasis Caused By A Viral Endosymbiont Can Be Prevented By Immunization With Its Viral Capsid, Patrick Castiglioni, Mary-Anne Hartley, Matteo Rossi, Florence Prevel, Chantal Desponds, Daniel T. Utzxchneider, Remzi-Onur Eren, Haroun Zangger, Livia Brunner, Nicolas Collin, Dietmar Zehn, F. Matthew Kuhlmann, Stephen M. Beverley, Nicolas Fasel, Catherine Ronet
Exacerbated Leishmaniasis Caused By A Viral Endosymbiont Can Be Prevented By Immunization With Its Viral Capsid, Patrick Castiglioni, Mary-Anne Hartley, Matteo Rossi, Florence Prevel, Chantal Desponds, Daniel T. Utzxchneider, Remzi-Onur Eren, Haroun Zangger, Livia Brunner, Nicolas Collin, Dietmar Zehn, F. Matthew Kuhlmann, Stephen M. Beverley, Nicolas Fasel, Catherine Ronet
Open Access Publications
No abstract provided.
The Brief Case: Central Nervous System Sparganosis In A 53-Year-Old Thai Man, Abigail L. Carlson, Nattapol Pruetpongpun, Aubonphan Buppajarntham, Pansachee Damronglerd, Neil W. Anderson, Anucha Apisarnthanarak
The Brief Case: Central Nervous System Sparganosis In A 53-Year-Old Thai Man, Abigail L. Carlson, Nattapol Pruetpongpun, Aubonphan Buppajarntham, Pansachee Damronglerd, Neil W. Anderson, Anucha Apisarnthanarak
Open Access Publications
No abstract provided.
Stress-Induced Reinstatement Of Nicotine Preference Requires Dynorphin/Kappa Opioid Activity In The Basolateral Amygdala, Stephanie K. Nygard, Nicholas J. Hourguettes, Gabe G. Sobczak, William A. Carlezon, Michael R. Bruchas
Stress-Induced Reinstatement Of Nicotine Preference Requires Dynorphin/Kappa Opioid Activity In The Basolateral Amygdala, Stephanie K. Nygard, Nicholas J. Hourguettes, Gabe G. Sobczak, William A. Carlezon, Michael R. Bruchas
Open Access Publications
UNLABELLED: The dynorphin (DYN)/kappa-opioid receptor (KOR) system plays a conserved role in stress-induced reinstatement of drug seeking for prototypical substances of abuse. Due to nicotine's high propensity for stress-induced relapse, we hypothesized that stress would induce reinstatement of nicotine seeking-like behavior in a KOR-dependent manner. Using a conditioned place preference (CPP) reinstatement procedure in mice, we show that both foot-shock stress and the pharmacological stressor yohimbine (2 mg/kg, i.p.) induce reinstatement of nicotine CPP in a norbinaltorphimine (norBNI, a KOR antagonist)-sensitive manner, indicating that KOR activity is necessary for stress-induced nicotine CPP reinstatement. After reinstatement testing, we visualized robust c-fos …
De Novo And Inherited Mutations In The X-Linked Gene Clcn4 Are Associated With Syndromic Intellectual Disability And Behavior And Seizure Disorders In Males And Females, E E Palmer, D K Grange, L Manwaring, Et Al
De Novo And Inherited Mutations In The X-Linked Gene Clcn4 Are Associated With Syndromic Intellectual Disability And Behavior And Seizure Disorders In Males And Females, E E Palmer, D K Grange, L Manwaring, Et Al
Open Access Publications
No abstract provided.
Adam17 Substrate Release In Proximal Tubule Drives Kidney Fibrosis, Eirini Kefaloyianni, Muthu Lakshmi Muthu, Jakob Kaeppler, Xiaoming Sun, Venkata Sabbisetti, Athena Chalaris, Stefan Rose-John, Eitan Wong, Irit Sagi, Sushrut S. Waikar, Helmut Rennke, Benjamin D. Humphreys, Joseph V. Bonventre, Andreas Herrlich
Adam17 Substrate Release In Proximal Tubule Drives Kidney Fibrosis, Eirini Kefaloyianni, Muthu Lakshmi Muthu, Jakob Kaeppler, Xiaoming Sun, Venkata Sabbisetti, Athena Chalaris, Stefan Rose-John, Eitan Wong, Irit Sagi, Sushrut S. Waikar, Helmut Rennke, Benjamin D. Humphreys, Joseph V. Bonventre, Andreas Herrlich
Open Access Publications
Kidney fibrosis following kidney injury is an unresolved health problem and causes significant morbidity and mortality worldwide. In a study into its molecular mechanism, we identified essential causative features. Acute or chronic kidney injury causes sustained elevation of a disintegrin and metalloprotease 17 (ADAM17); of its cleavage-activated proligand substrates, in particular of pro-TNFα and the EGFR ligand amphiregulin (pro-AREG); and of the substrates' receptors. As a consequence, EGFR is persistently activated and triggers the synthesis and release of proinflammatory and profibrotic factors, resulting in macrophage/neutrophil ingress and fibrosis. ADAM17 hypomorphic mice, specific ADAM17 inhibitor-treated WT mice, or mice with inducible …
Multiple Mechanisms For Processing Reward Uncertainty In The Primate Basal Forebrain, Noah M. Ledbetter, Charles D. Chen, Ilya E. Monosov
Multiple Mechanisms For Processing Reward Uncertainty In The Primate Basal Forebrain, Noah M. Ledbetter, Charles D. Chen, Ilya E. Monosov
Open Access Publications
UNLABELLED: The ability to use information about the uncertainty of future outcomes is critical for adaptive behavior in an uncertain world. We show that the basal forebrain (BF) contains at least two distinct neural-coding strategies to support this capacity. The dorsal-lateral BF, including the ventral pallidum (VP), contains reward-sensitive neurons, some of which are selectively suppressed by uncertain-reward predictions (U(-)). In contrast, the medial BF (mBF) contains reward-sensitive neurons, some of which are selectively enhanced (U(+)) by uncertain-reward predictions. In a two-alternative choice-task, U(-) neurons were selectively suppressed while monkeys chose uncertain options over certain options. During the same choice-epoch, …