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Open Access Dissertations

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The Synthesis Of Lysoliponucleotide Analogs: A New Class Of Potential Anticancer Agents, Timothy Paul Wunz Jan 1982

The Synthesis Of Lysoliponucleotide Analogs: A New Class Of Potential Anticancer Agents, Timothy Paul Wunz

Open Access Dissertations

No abstract provided.


Androgen Biosynthesis In The Testis, Mary A. Acciardi Jan 1982

Androgen Biosynthesis In The Testis, Mary A. Acciardi

Open Access Dissertations

The kinetic parameters of testicular steroid synthesizing enzymes involved in the Δ4 and Δ5 pathway s for testosterone production were examined in four species. Testis microsomes were prepared as a source of steroidogenic enzymes. Radiolabeled steroid-intermediates were used as substrates and products were separated by thin layer chromatography. Michaelis constants, (k0.5), and Vmax values were determined for 3 B-Hydroxysteroid oxidoreductase (EC 1.1.1.145), 17α-Hydroxylase (EC 1.14.99.9) and C17-C20 Lyase reactions using Δ4 and Δ5 substrates.

The purpose of the study was to develop a kinetic model for predicting the predominant steroidogenic …


Fat Dispersion Mechanisms In Proteinaceous And Farinaceous Matrices, Demetrios Kazantzis Jan 1982

Fat Dispersion Mechanisms In Proteinaceous And Farinaceous Matrices, Demetrios Kazantzis

Open Access Dissertations

No abstract provided.


Bioaccumulation And Bioconversion Of Dietary Labeled Fatty Acids In The Short Food Chain: Rice Bran To Artemia To Rainbow Trout And Winter Flounder, Paul Scott Schauer Jan 1982

Bioaccumulation And Bioconversion Of Dietary Labeled Fatty Acids In The Short Food Chain: Rice Bran To Artemia To Rainbow Trout And Winter Flounder, Paul Scott Schauer

Open Access Dissertations

No abstract provided.


An Investigation Of Some Factors Controlling Solute Transport Across Liquid Membranes, Andrea Panaggio Jan 1982

An Investigation Of Some Factors Controlling Solute Transport Across Liquid Membranes, Andrea Panaggio

Open Access Dissertations

Accurate, precise, sensitive and reproducible experimental protocols using high pressure liquid chromatographic assay techniques (HPLC) have of solutes across liquid membranes. A simple model, previously developed by Rhodes and co-workers, used to describe the kinetics of solute transport across liquid membranes was evaluated and some formulation aspects of emulsions for use as liquid membranes were studied.

The removal of solutes from an external aqueous phase by a liquid membrane was found to be influenced by a number of factors including initial solute concentration, pH of the external aqueous phase, and temperature of the system. As the initial concentration of solute …


Androgen Biosynthesis In The Testis: I. Kinetic Characterization Of The Steroidogenic Pathways In Guinea Pig, Rabbit, Dog And Rat Testis Microsomes. Ii. The Effect Of Ascorbic Acid On 3-B Hydroxysteroid: Nadoxidoreductase Activity In The Testis, Mary A. Acciardi Jan 1982

Androgen Biosynthesis In The Testis: I. Kinetic Characterization Of The Steroidogenic Pathways In Guinea Pig, Rabbit, Dog And Rat Testis Microsomes. Ii. The Effect Of Ascorbic Acid On 3-B Hydroxysteroid: Nadoxidoreductase Activity In The Testis, Mary A. Acciardi

Open Access Dissertations

No abstract provided.


Supraoptimal Temperature Stress And Nitrogen Nutrition In Kentucky Bluegrass (Poa Pratensis L.), John Townley Law Jr. Jan 1982

Supraoptimal Temperature Stress And Nitrogen Nutrition In Kentucky Bluegrass (Poa Pratensis L.), John Townley Law Jr.

Open Access Dissertations

No abstract provided.


Microbiological Effect Of Maillard Reaction Products, Hsing-Chen Chen Jan 1982

Microbiological Effect Of Maillard Reaction Products, Hsing-Chen Chen

Open Access Dissertations

No abstract provided.


Investigations On Marine Diatom Resting Spores, Fred Wellington French Iii Jan 1982

Investigations On Marine Diatom Resting Spores, Fred Wellington French Iii

Open Access Dissertations

No abstract provided.


The Dynamics Of Summer Phytoplankton Populations In Narragansett Bay (Rhode Island), Miles Jonathan Furnas Jan 1982

The Dynamics Of Summer Phytoplankton Populations In Narragansett Bay (Rhode Island), Miles Jonathan Furnas

Open Access Dissertations

No abstract provided.


Child Maltreatment: A Critical Review Of The Literature And Intervention Programs, Richard Strean Solomon Jan 1982

Child Maltreatment: A Critical Review Of The Literature And Intervention Programs, Richard Strean Solomon

Open Access Dissertations

No abstract provided.


The Effects Of Marginal Deficiencies Of Ascorbic Acid And Alpha-Tocopherol On The Natural Resistence And Immune Response Of Rainbow Trout (Salmo Gairdneri), Vicki Suzette Blazer Jan 1982

The Effects Of Marginal Deficiencies Of Ascorbic Acid And Alpha-Tocopherol On The Natural Resistence And Immune Response Of Rainbow Trout (Salmo Gairdneri), Vicki Suzette Blazer

Open Access Dissertations

No abstract provided.


The Use Of Exogenous Digestive Enzymes In Shrimp Diets (Clam), Paul David Maugle Jan 1982

The Use Of Exogenous Digestive Enzymes In Shrimp Diets (Clam), Paul David Maugle

Open Access Dissertations

No abstract provided.


Protein Isolates And Enzymatically Modified Proteins From The Frame Portion Of Solid Fish Waste, Joseph Montecalvo Jr. Jan 1981

Protein Isolates And Enzymatically Modified Proteins From The Frame Portion Of Solid Fish Waste, Joseph Montecalvo Jr.

Open Access Dissertations

No abstract provided.


Enzymatic Processes To Preserve Fresh Fish, Cynthia Ellen Field Jan 1981

Enzymatic Processes To Preserve Fresh Fish, Cynthia Ellen Field

Open Access Dissertations

No abstract provided.


Evaluation Of The Nutritional And Toxicological Effects Of Maillard Browned Proteins In The Rat, Stephen Joseph Pintauro Jan 1981

Evaluation Of The Nutritional And Toxicological Effects Of Maillard Browned Proteins In The Rat, Stephen Joseph Pintauro

Open Access Dissertations

No abstract provided.


The Preparation, Physiochemical Characteristics And Functional Properties Of Chicken Blood Plasma And Its Isolates, Pavlos Achilles Karakoltsidis Jan 1981

The Preparation, Physiochemical Characteristics And Functional Properties Of Chicken Blood Plasma And Its Isolates, Pavlos Achilles Karakoltsidis

Open Access Dissertations

No abstract provided.


Cognitive Deficits In Alcohol Troubled Females: A Comparative Study, Francis Raymond Sparadeo Jan 1981

Cognitive Deficits In Alcohol Troubled Females: A Comparative Study, Francis Raymond Sparadeo

Open Access Dissertations

No abstract provided.


Human Pharmacokinetics Of 5-Formyl Tetrahydrofolate, Bruce Kenneth Birmingham Jan 1981

Human Pharmacokinetics Of 5-Formyl Tetrahydrofolate, Bruce Kenneth Birmingham

Open Access Dissertations

The purpose of this study was to determine the pharmacokinetics of calcium leucovorin in normal subjects and in patients undergoing High-Dose methotrexame therapy for the treatment of neoplastic disease. By characterizing the disposition of leucovorin it was hoped that the efficacy of the aethotrexate therapy might be improved, while at the same time, the incidence of toxicity could be diminished.

An assay for the separation and quantification of leucovorin in serum was developed. The reduced folate vas extracted from serum using reverse-phase chromatographic minicolumns and a paired-ion reagent. Leucovorin was eluted from this system in methanol and evaporated to dryness …


Production And Characterization Of Enzymes From Animal Waste Material, Joaquim Francisco Da Ponte Tavares Jan 1981

Production And Characterization Of Enzymes From Animal Waste Material, Joaquim Francisco Da Ponte Tavares

Open Access Dissertations

No abstract provided.


Simultaneous Saccharification And Fermentation Of Cellulose To Ethanol, Paul Thomas Shea Jan 1981

Simultaneous Saccharification And Fermentation Of Cellulose To Ethanol, Paul Thomas Shea

Open Access Dissertations

No abstract provided.


Studies Of The Reproduction, Nutrition And Symbiosis With Zooxanthellae Of The Temperate Scleractinian Coral Astrangia Danae, Alina Szmant Froelich Jan 1980

Studies Of The Reproduction, Nutrition And Symbiosis With Zooxanthellae Of The Temperate Scleractinian Coral Astrangia Danae, Alina Szmant Froelich

Open Access Dissertations

No abstract provided.


The Vertical Transmission Of Avian Adenovirus Associated Virus, George Joseph Dawson Jan 1980

The Vertical Transmission Of Avian Adenovirus Associated Virus, George Joseph Dawson

Open Access Dissertations

No abstract provided.


Metabolic Requirement Of Cucurbita Pepo For Boron, Carol Jean Lovatt Jan 1980

Metabolic Requirement Of Cucurbita Pepo For Boron, Carol Jean Lovatt

Open Access Dissertations

No abstract provided.


A Mechanism Of Action Of Gold In Rheumatoid Arthritis. A Biochemical And Morphological Investigation Of The Direct Effect Of Gold Sodium Thiomalate (Gst) On Human Synovial Cells In Culture, Ronald Lee Goldberg Jan 1980

A Mechanism Of Action Of Gold In Rheumatoid Arthritis. A Biochemical And Morphological Investigation Of The Direct Effect Of Gold Sodium Thiomalate (Gst) On Human Synovial Cells In Culture, Ronald Lee Goldberg

Open Access Dissertations

Gold sodium thiomalate (GST) effects on cultured rheumatoid synovial cells were used as a model to investigate a mechanism which can explain clinical benefits gained by patients from gold therapy. Synovial tissue obtained from patients with rheumatoid arthritis who were undergoing reconstructive joint surgery was used to obtain explant culture of synovial cells. The experiments described were performed on growing monolayer cultures during the second to fifth passages. Synovial cells were exposed to GST at pharmacologically relevant concentrations (10-100 uM). Vacuoles were found by phase contrast microscopy in synovial cells in culture after 2 days of exposure to 100 uM …


A Study Of Cognitive Functioning Of Social Drinkers, Joy Reed Macvane Jan 1980

A Study Of Cognitive Functioning Of Social Drinkers, Joy Reed Macvane

Open Access Dissertations

No abstract provided.


Growth, Activity And Metabolism Studies Of Summer Flounder Paralichthys Dentatus (L.) Under Laboratory Conditions, Grace Klein-Macphee Jan 1979

Growth, Activity And Metabolism Studies Of Summer Flounder Paralichthys Dentatus (L.) Under Laboratory Conditions, Grace Klein-Macphee

Open Access Dissertations

No abstract provided.


Phosphorus Metabolism In The Oceanic Dinoflagellate Pyrocystis Noctiluca, Richard Bob Rivkin Jan 1979

Phosphorus Metabolism In The Oceanic Dinoflagellate Pyrocystis Noctiluca, Richard Bob Rivkin

Open Access Dissertations

No abstract provided.


Characterization Of An Endogenous Inhibitor Of Prolyl Hydroxylase, Clinton Oscar Chichester Jan 1979

Characterization Of An Endogenous Inhibitor Of Prolyl Hydroxylase, Clinton Oscar Chichester

Open Access Dissertations

No abstract provided.


Escherichia Coli Colonization Of The Intestinal Tract: A Model For The Study Of Colonization Mechanisms And The Predictive Value Of Lysine Decarboxylase, Robert William Pilsucki Jan 1979

Escherichia Coli Colonization Of The Intestinal Tract: A Model For The Study Of Colonization Mechanisms And The Predictive Value Of Lysine Decarboxylase, Robert William Pilsucki

Open Access Dissertations

No abstract provided.