Digital Commons Network^™

The Application Of Statistical Modeling To Identify Genetic Associations With Mild Traumatic Brain Injury Outcomes, Caroline Schott

Masters Theses

"Traumatic brain injury (TBI) is a growing health concern, with millions of TBI diagnoses in the United States each year. The vast majority of TBI diagnoses are mild traumatic brain injuries (mTBI), which can be challenging to manage due to variation in symptoms and outcomes. Most individuals with mTBI successfully recover quickly, but a small subset has a delayed recovery. Although the factors that contribute to this variation in recovery are not clearly understood, it is possible that genetic differences may play a role. Very few studies have investigated the association between single nucleotide polymorphisms (SNPs) with mTBI outcomes and …

Application Of Nitrate To An Anaerobic Subsurface Bioremediation, Cassie Marie Roberts

Masters Theses

"The highly contaminated subsurface matrix of the Baird and McGuire Superfund site is currently threatening the health and safety of the surrounding environment of Holbrook, MA. Contaminants of significant concern due to high concentration are inorganic arsenite and petroleum hydrocarbons, such as naphthalene. Parsons Corporation and the Massachusetts Department of Environmental Protection have implemented a bioremediation pilot to attempt to degrade the hydrocarbons and arsenic with the application of nitrate. The nitrate would act as an electron acceptor for biodegradation of the hydrocarbon contaminants, produce nitrite that would oxidize reduced iron, and iron oxides would sequester arsenic. Preliminary data showed …

Evaluation Of Mesenchymal Stem Cells In Autoimmune Disease: A Systematic Review And Meta-Analysis, Hailey Nicole Swain

Masters Theses

"Mesenchymal stem cells, also known as multipotential stem/progenitor cells and mesenchymal stem/progenitor cells, are denoted by the acronym MSCs. MSCs can differentiate into multiple lineages from different germ layers in vitro, and in limited situations, in vivo. MSCs have broad anti-inflammatory and immune-modulatory properties, which is the greatest focus of MSCs in clinical testing. Despite their promise and use in over 950 clinical trials, pivotal questions remain unanswered. Recent clinical trials have demonstrated that when MSCs are harvested from autoimmune patients, they show a reduction in their therapeutic efficacy in comparison to MSCs from a healthy person. Identifying quality MSCs …

Environmental Dna Metabarcoding As A Tool For Fish Community Assessment In Wetlands, Eric Ludwig

Masters Theses

"Environmental DNA (eDNA) metabarcoding is a genetically based method of assessing biodiversity in aquatic environments. While the efficacy of eDNA surveys has been well documented in riverine and marine systems, it has been relatively underemployed in freshwater wetland environments. In this study, we conducted an eDNA metabarcoding survey of fish diversity and its seasonal variation in a wetland along the Mississippi River in the Missouri Bootheel. Samples were collected from both permanent and seasonal water bodies including oxbow lakes, a shallow, man-made lake, a ditch, and a slough. For each of the 28 sites in this study, three water samples …

Sentiment Strength And Topic Recognition In Sentiment Analysis, Esi A.R. Adeborna

Masters Theses

"Current sentiment analysis methods focus on determining the sentiment polarities (negative, neutral or positive) in users’ sentiments. However, in order to correctly classify users’ sentiments into their right polarities, the strengths of these sentiments must be considered. In addition to classifying users’ sentiments into their correct polarities, it is important to determine the sources and topics under which users’ sentiments fall. Sentiment strength helps as to understand the levels of customer satisfaction toward products and services. Sentiment topics on the other hand, helps to determine the specific product/service areas associated with user sentiments. This paper proposes two sentiment analysis approaches. …

Scalable And Continuous Fabrication Of Dendrimer Based Gene And Protein Delivery Systems, Joseph Johnston

Masters Theses

"Gene and protein therapeutics play critical roles in the drug market and represent the future of biopharmaceuticals. Polymeric nanoparticle-based gene/protein delivery systems are promising owing to their ability to protect the cargo from degradation, improving intracellular delivery and transfection efficiency as well as abundant sources and flexibility to be modified. Yet the successful industrialized production and clinical application of polymeric nanoparticle-based delivery systems have long been limited by unsatisfied delivery efficiency and the lack of reproducible and scalable methods for the preparation of uniform nanoparticles with good batch to batch consistency. To address the unsatisfied efficacy and difficulty in scale-up …

Prediction And Root-Cause Analysis For Smart Speaker Intentional Electromagnetic Interference Attacks, Tanner Fokkens

Masters Theses

"Smart home and Internet of Things (IoT) devices have become ubiquitous in homes over the past decade. The smart speaker itself is often the device that interfaces all these devices together. Because of this, the smart speaker can become a point of attack for someone trying to exploit or hack into the smart home devices. In the past few years, it was discovered that smart speakers with microwave electromechanical system (MEMS) microphones are susceptible to intentional electromagnetic interference (I-EMI) attacks by modulating an audio command to a high-frequency carrier signal. This attack allows for command recognition for long-distances and smart …

Improved Decap Model And Placement Optimization Algorithm For Power Distribution Network Design, Jack Juang

Masters Theses

"Decoupling capacitors (decaps) are used in power distribution network (PDN) design to act as a low impedance return path for noise and act as a local source of charge when required by integrated circuits (IC). For placement of decaps, which can number even to the hundreds, many algorithms have been proposed including genetic algorithms (GA), iterative algorithm, and machine learning methods.

One limitation of iterative decap placement algorithms (adding one decap at a time) is how the construction of the algorithm affects the form of the final solution. For example, if the reward function (used in GA and machine learning …

A Hybrid Framework For Critical Infrastructures Interdependency Modeling, Simulation, And Analysis, David Corder Hinton

Masters Theses

"Flow system models, also known as flow network models, encompass vastly complex, ever-expanding problem sets which comprise the foundation for maintenance, operation, and improvement of critical infrastructures around the world. The stable operation of these vast critical infrastructures is fundamental to the continued advancement of modern society. These infrastructures are tightly interdependent and vulnerable to interruption by both natural circumstance and malicious targeting. This necessitates representation of such critical infrastructures and their multi-domain interdependencies in defense focused constructive and virtual simulation environments as a matter of national interest and security. By breadth exploration of the problem space, this work body …

Flight Software Development For A University-Class Microsatellite Mission, Yumeka Nagano

Masters Theses

"The purpose of this research is to present the software development process used by the Command and Data Handling (C&DH) subsystem as a part of a microsatellite mission underway at the Missouri University of Science and Technology. The mission's objective is to evaluate the performance of an innovative cold gas propulsion system for use in formation flying applications and the incorporation of a stereoscopic imaging sensor used to measure the satellite pair's relative position and velocity vectors in real time. C&DH uses a Raspberry Pi 3 Model B as the flight computer running a Linux environment, and the flight code …

Development And Testing Of A Hyperbaric Aerodynamic Levitator For Containerless Materials Research, Sydney Elizabeth Boland

Masters Theses

"This research focused on the development and testing of a hyperbaric aerodynamic levitator for container less materials research of specimens at temperatures greater than 2000°C and pressures up to 10.3 MPa (1500 psi). The effect of specimen size, specimen density, pressure, and flow rate on the levitation behavior was studied. Lightweight specimens demonstrated two stable levitation regimes that were speculated to be associated with a change in the turbulent wake structure. The hyperbaric aerodynamic levitator was also used to determine the effect of pressure on the heat transfer by studying the melting behavior of a levitated 3.0 mm diameter alumina …

Designing Exterior Lighting For Safety And Comfort While Minimizing Light Pollution, Energy Consumption, And Cost, Stephen Michael Simmons

Masters Theses

"Artificial light at night brings many benefits to society. However, these benefits do not come without costs. One environmental issue that is often overlooked in the design of public spaces and infrastructure is light pollution. At the expense of large amounts of energy, light pollution causes numerous harmful effects on human health, ecosystems, and the night sky. Today, the problem is becoming more widespread, especially with the increasing use of bright, white LED luminaires. Thus, it is imperative for designers and engineers to create smarter lighting designs that not only allow for safety and comfort at night but also promote …

A Real-Time Microwave Camera Using Zero-Bias Diode Detector, Liang Liu

Masters Theses

"This thesis presents the design of a microwave camera that utilizes a two-dimensional array of elliptical slot antennas and diode detectors to quickly and accurately locate radiation sources. Unlike traditional scanning techniques like ESM and holography, which rely on mechanical scanning, require a long measurement time, and are prone to mechanical errors, the microwave camera operates quickly and efficiently by using electronic switching to access the output of each detector. This results in a more precise and efficient means of locating radiation sources'--Abstract, p. iii

Implementing Effective University - Level Small Satellite Assembly, Integration, And Testing Procedures, Tyler Patrick Hoover

Masters Theses

"As applications for satellite assets grow within government and commercial spheres, demand for aerospace engineers and related technicians has pushed universities to develop graduates with relevant knowledge in the field. As such, universities began to grow university satellite programs to give members hands-on experience and a background of working on satellite systems before entering the workforce.

The M-SAT team at Missouri University of Science and Technology, along with contributions and assistance from the Air Force Research Laboratory and NASA, are progressing their first satellite mission through assembly, integration, and testing (AIT) development. This document serves to give a background into …

A Network Of Low-Cost Multi-Pollutant Air Quality Sensors For Evaluating Fine-Scale Exposure Disparity In Twin Cities, Mn, P M Varuni Abhayaratne

Masters Theses

"Poor air quality is detrimental to health and is a leading environmental risk factor for early death globally. The massive scale of urbanization and population growth has led urban air quality to become a global concern as the release of air pollutants into the atmosphere continues to increase. Air quality has traditionally been monitored using reference-grade monitoring stations that are expensive and sparsely distributed. Low-cost sensors can complement existing regulatory networks to provide more spatial detail, capturing fine-scale variations. This study investigates spatiotemporal pollutant patterns, exposure disparities and environmental justice using data collected from a two-year (2019-2021) deployment of a …

Tropospheric Correction For Insar Using Machine Learning, Ngo Hi Kenny Yue

Masters Theses

"Interferometric Synthetic Aperture Radar (InSAR) is a popular technique for studying Earth's surface deformation caused by phenomena like earthquakes and subsidence. However, its accuracy is limited by tropospheric delays caused by water vapor in the atmosphere. This limitation can be overcome by using methods that correct for tropospheric noise, such as statistical, empirical, and predictive approaches. This study explores the potential of using machine learning algorithms to predict the zenith total delay caused by tropospheric effects in InSAR measurements. The study employs two different machine learning algorithms, random forest and neural networks, to learn the relationship between numerical weather prediction …

Optimizing The Placement Of Multiple Uav--Lidar Units Under Road Priority And Resolution Requirements, Zachary Michael Osterwisch

Masters Theses

"Real-time road traffic information is crucial for intelligent transportation systems (ITS) applications, like traffic navigation or emergency response management, but acquiring such data is tremendously challenging in practice because of the high costs and inefficient placement of sensors. Some modern ITS applications contribute to this problem by equipping vehicles with multiple light detection and ranging (LiDAR) sensors, which are expensive and gather data inefficiently; one solution that avoids vehicle-mounted LiDAR acquisition has been to install elevated LiDAR instruments along roadways, but this approach remains unrefined. The eventual development of sixth-generation (6G) wireless communication will enable new, creative solutions to solve …

Tailoring A System Engineering And Management Plan For A University Satellite Team, Jacob D. Anderson

Masters Theses

"A Systems Engineering and Management Plan (SEMP) helps enable a successful engineering project or team. All university teams working on satellite development encounter similar obstacles that are not commonly seen in industry. As a result, university teams must determine new approaches to solve these unique and difficult problems. A SEMP can mitigate risks, solve problems, and provide streamlined solutions. A modified SEMP is proposed along with guidance for implementing it into a new team and an existing team.

The adopted SEMP provides a road map for the technical execution and program management of a university team. The SEMP should be …

Rapid-Throughput Analysis Of 1,4-Dioxane In Plants By Centrifugal Sampling And Phytoforensic Analysis For Site Delineation And Assessing Enhanced Rhizodegradation, Anthony Eberechukwu Oha

Masters Theses

"Owing to its broad use and environmental persistence, 1,4-dioxane (dioxane) poses a notable threat to public health and is recalcitrant to traditional remedial systems. Dioxane moves readily in an aqueous environment and is an emerging contaminant in drinking water, surface water, groundwater, and wastewater. The extent of dioxane in the biosphere is also difficult to delineate, particularly in the subsurface. Phytoremediation has demonstrated the potential for dioxane groundwater remediation. Recent findings indicate that plant-microbial symbiosis may be more advantageous for limiting potential transport and transfer into plant tissues and the atmosphere. Bioaugmentation of the rhizosphere paired with soil amendments has …

Computer Vision In Adverse Conditions: Small Objects, Low-Resoltuion Images, And Edge Deployment, Raja Sunkara

Masters Theses

"Computer vision based on deep learning is an essential field that plays a significant role in object detection, image classification, semantic segmentation, instance segmentation, and other applications. However, these models face significant challenges in adverse conditions, such as small objects, low-resolution images, and edge deployment. These challenges limit the accuracy and efficiency of computer vision algorithms, making it difficult to obtain reliable results.

The primary objective of this thesis is to assess the performance of deep learning- based computer vision models in challenging conditions and provide viable solutions to overcome the obstacles. The study will specifically address three key challenges, …

Mat: Genetic Algorithms Based Multi-Objective Adversarial Attack On Multi-Task Deep Neural Networks, Nikola Andric

Masters Theses

"Vulnerability to adversarial attacks is a recognized deficiency of not only deep neural networks (DNNs) but also multi-task deep neural networks (MT-DNNs) that attracted much attention in the past few years. To the best of our knowledge, all multi-task deep neural network adversarial attacks currently present in the literature are non-targeted attacks that use gradient descent to optimize a single loss function generated by aggregating all loss functions into one. On the contrary, targeted attacks are sometimes preferred since they give more control over the attack. Hence, this paper proposes a novel targeted multi-objective adversarial ATtack (MAT) based on genetic …

Dynamic Discounted Satisficing Based Driver Decision Prediction In Sequential Taxi Requests, Sree Pooja Akula

Masters Theses

"Ridesharing platforms rely on connecting available taxi drivers to potential passengers to maximize their revenue. However, predicting the stopping decision made by every driver, i.e., the final task performed during a given day, is crucial to achieving this goal. Unfortunately, little research has been done on predicting drivers’ stopping decisions, especially when they deviate from expected utility maximization behavior. This research proposes a Dynamic Discounted Satisficing (DDS) heuristic to model and learn the task at which human agents will stop working for that day, assuming that the human agents are taking sequential decisions based on their preference order. We apply …

Selecting Consolidation Procedures For Making Concrete Specimens, Paige Marie Toebben

Masters Theses

"The goal of this research was to reevaluate ASTM C31 Standard Practice for Making and Curing Concrete Test Specimens in the Field, as well as deepen our understanding of the relationship between the consolidation process, concrete composition, and workability. An improved understanding of this area will help to reduce variability in concrete quality. The project involved evaluating the effect of different consolidation methods on concrete specimens with changing levels of workability. To do this, concrete cylinders were created with varying viscosities by adjusting the water-to-cement ratio (w/c) and water-reducing agent. More cylinders were created with varying paste volumes while keeping …

Meta-Analysis Of Mesenchymal Stem Cell Gene Expression Data From Obese And Non-Obese Patients, Dakota William Shields

Masters Theses

"The prevalence of gene expression microarray datasets in public repositories gives opportunity to analyze biologically interesting datasets without running the laboratory aspect in house. Such experimentation is expensive in terms of finances, time, and expertise, which often results in low numbers of replicates. Meta-analysis techniques attempt to overcome issues due to few biological or technical replicates by combining separate experiments together to increase statistical power. Proper statistical considerations help to offset issues like simultaneous testing of thousands of genes, unintended hybridization, and other noises.

Microarrays contain light intensities from tens of thousands of hybridized probes giving a measure of gene …

Investigation Of Defect Production And Displacement Energies In Wurtzite Aluminum Nitride, Sean Anderson

Masters Theses

"Aluminum Nitride is an active element of sensors that monitor the performance and well-being of the nuclear reactors due to its piezoelectric properties. Yet, the variations of its properties under irradiation are largely unexplored. We report the results of the molecular dynamics simulations of the structural changes in AlN under irradiation via the knock-on atom technique. By creating and evolving the irradiation cascades due to energetic particle interaction with the atom of the crystalline lattice we determine the rate of the defect production as a function of the deposited energy. Further, we determine a displacement energy, a key characteristic that …

Zoom Fatigue And Virtual Interviewing: The Effects Of Interpersonal Distance, Lillian Rose Schell

Masters Theses

"This research examines breaches of interpersonal distance, one of the proposed causes of Zoom fatigue, within the context of a job interview. It is proposed that when an interviewer perceives a job applicant to be close to them, Zoom fatigue increases and ratings of the applicant decrease. Participants completed a Zoom Exhaustion and Fatigue scale before and after watching an asynchronous video interview in which the size of the job applicant’s face varied between conditions. It was found that breaches of interpersonal distance did not influence self-reported Zoom fatigue. However, breaches of interpersonal distance did influence ratings of the job …

Static I-V Curve And Aging Test For Pim Characterization In Metallic Contacts, Kalkidan Anjajo

Masters Theses

"Spring clips and fabric-over-foams (FOFs) are widely used in mobile devices for electrical connection purposes. However, the imperfect metallic connections tend to induce passive intermodulation (PIM), resulting in a receiver sensitivity degradation, known as RF desensitization. Due to the complexity of the PIM characterization, there is not yet a way to evaluate PIM performance using a simple setup for environments like factories. In this study, a current-voltage (I-V) behavior-based PIM evaluation method is proposed and validated with various metallic contacts and contact forces. The test results demonstrated the feasibility of the PIM performance evaluation based on the measured static I-V …

Incorporating Novel Sensors For Reading Human Health State And Motion Intent Into Real-Time Computing Systems, Adam Sawyer

Masters Theses

"Integrating sensors that read states of the human body into everyday life is an increasing desire, especially with the rise of deep learning which requires vast stores of data to make predictions. This work explores integrating these sensors into the human experience through two methods and recording the results. The first of these methods integrates a MXene based field-effect transistor sensor for the 2019-nCov spike protein with a mobile app. This allows the user to read how saturated their breath is with Covid-19. The second method integrates 3D-printed pressure sensors, and a motion capture system, into a glove to read …

Microscopic Traffic Simulation Modeling And Communication Tool For Post-Disaster Evacuation Routing, Nicholas Kutheis

Masters Theses

"This research evaluated the effectiveness of conducting traffic simulation models and developing a mobile application to serve as a communication channel for emergency evacuation preparation and routing. An iOS and Android app was developed to display emergency events to users with suggested routes for evacuation and a microscopic traffic simulation model was conducted for the St. Louis (MO) metropolitan region that analyzed various road networks with projected evacuation demand.

A mobile application coded in Swift (Apple) and Kotlin (Android) featured an emergency notification screen that displayed the type of emergency warning (e.g., earthquake, flood, or no warnings) with provided routes …

Suppressing Aluminum/Silica Exchange Reaction Between High Aluminum Steel And Mold Flux During Continuous Casting Process, Kuanysh Nurbekuly Yermukhanbetov

Masters Theses

"Mold flux plays one of the critical roles in continuous casting of steel. It performs five primary functions: thermal and chemical insulation, lubrication between the steel strand and mold, absorption of inclusions, and promotion of even heat flux. The aluminum/silica exchange reaction occurring between steel and mold flux during the continuous casting process poses significant challenges in the steel industry. This reaction can lead to various defects in the cast product and adversely affect its surface quality, as well as downstream processing.

In this work, effectiveness of two approaches, namely slag dopant additions and electrochemical techniques, in suppressing the exchange …