Digital Commons Network^™

Reprograming Neuronal Cells By Overexpression Of Fibroblast-Specific Transcription Factors, Abdulmohsen Alanazi

Masters Theses

In mammals, a complex system of regulatory signals distinguishes tissues, structures and functions. Combinations of transcription factors and co-factors regulate activation and repression of genes that result in cellular differentiation. Whole genome arrays allow the monitoring of genomic expression in specific tissues. Fibroblast microarray studies have shown candidate genes that may be involved in fibroblast identification, including genes that express transcription factors Prrx1, Snai2 and Twist1. A previous study showed that the Prrx1 and Snai2 could reactivate a fibroblast phenotype in hybrid cells that had lost fibroblast identity. Furthermore, overexpression of these factors in liver-derived cells strongly repressed liver gene …

The Transitional Experiences Of International Students Studying In The United States, Philip Fennell

Masters Theses

This study sought to explore the real-life experiences of two international students and the impact on their transition to a United States college. A narrative qualitative approach was used to incorporate the stories of international students as shared by their own words. Their stories were used to identify similarities and differences including resources they utilized and their interactions with others. International students all share different cultural backgrounds and characteristics. Nonetheless, they will each have their own unique experiences, as well as have different ways of reacting and responding to those experiences. We must put in the effort of listening to …

The Determinants Of Sectoral Employment In Nepal, Thaman P. Bastola

Masters Theses

This paper uses the data from 1991 to 2019 to analyze the determinants of employment in agriculture, industrial, and service sectors of Nepal. The data are gotten from the world development indicators (WDI), human development indicators (HDI) and Nepal Rastra Bank (NRB). The results show that significant determinants of employment in Nepal areeducation, health, population growth, interest rate, inflation rate and political conflict.The education, health, population growth, and inflation are inversely related to the employment of agricultural sectors employment. Likewise, the industrial sector employment is positively affected by the health and political conflict, and negatively affected by the level of …

Representations Of Africa In Us Media: A Semiotic Analysis Of Ebola: The Doctor’S Story And Body Team 12, Olubusola Akinpelu

Masters Theses

The Western media has often been criticized for biased coverage of happenings in and around Africa. The 2014 Ebola outbreak created a lot of media attention for West Africa, and by extension, the entire continent. This study examined to what extent postcolonial discourses were infused in two films from the HBO Trilogy: Ebola: The Doctor’s Story (2015) and Body Team 12 (2015). To analyze these texts, I took a semiotic approach by identifying, describing and interpreting the signs in both films, to discuss the postcolonial discourses in three broad themes. Ebola: The Doctor’s Story (2015) was analyzed in the …

Adjustment To Life In America: Black African Graduate Level Students, Denver Daniels

Masters Theses

The purpose of the study was to examine what challenges Black African graduate students face when adjusting to life in the United States. A secondary concern was to examine what coping strategies were used during the transition. A qualitative approach was used to interview the participants and through coding, develop themes related to their time as graduate students.

This study concluded that there were a number of issues that Black African graduate students face. The students reported that they experienced homesickness, culture shock, and discrimination during their time at school. Specific themes also emerged as to how they coped with …

Financial Development In Developing Countries, Obinna Franklin Ezeibekwe

Masters Theses

What are the economic, political, institutional, socio-cultural, and geographical determinants of financial development in developing countries? This paper uses the two-way fixed effects (with clustered standard errors) and annual panel data from 1980 to 2018 for 69 developing countries in sub-Saharan Africa, Middle East and North Africa, East and South Asia, Latin America, and the Caribbean to address this question. The principal component analysis is employed to construct a financial development index based on three financial development indicators. This study builds on previous studies by introducing new potential determinants of financial development, such as the perception of corruption, and by …

Panhellenic Women's Leadership Development And Self-Efficacy, Caitlyn Gastfield

Masters Theses

Substantial research has been done on self-efficacy as well as a growing amount of research on women in leadership. This qualitative study examined the perceived relationship between leadership development opportunities given to Panhellenic women and their perceived level of self-efficacy. Three semi-structured interviews were conducted at a regional, mid-sized institution in the Midwest with undergraduate women holding leadership positions in their respective Panhellenic organizations. The results found in this study support many of the previous findings in research in relation to the importance of leadership development and self-efficacy. Many types of leadership development opportunities emerged, from informal peer support to …

The Path To Persistence: How Highly-At-Risk Students Persevere To Graduation Day, Alexis Kaine Straub

Masters Theses

This phenomenological study looked at highly-at-risk college seniors who exhibited four out of the eight risk factors defined by the institution where the study took place. The purpose was to gain insight into how highly-at-risk college seniors persist to graduation by discovering what protective factors they utilized in their college career as well as the role resiliency and/or grit may have played. The participants were five undergraduate students who were enrolled at a mid-sized, public university in the rural Midwest. They responded to questions in one semi-structured interview designed to capture their experiences about college starting from high school until …

Important Factors Influencing Attendance At Northwoods League Games, Ryan Eiche

Masters Theses

The purpose of this study was to examine the importance of various factors as they related to attendance at Northwoods League baseball games. This league was an ideal fit for the study as little research has been conducted on this level of baseball. A survey was sent out via the Facebook page of the Lakeshore Chinooks to gather responses from fans on what factors encouraged attendance. Fans were asked to then rate how important each factor was on a five-point sliding scale. The research revealed that situational factors such as convenience, day and time, and weather of the game were …

Aging Techniques & Population Dynamics Of Blue Suckers (Cycleptus Elongatus) In The Lower Wabash River, Dakota S. Radford

Masters Theses

The Blue Sucker, Cycleptus elongatus, occurs in large rivers primarily in the Mississippi River basin. Their imperiled status has called attention to the need for its management and protection. Estimating age is crucial for directing management, but past studies have varied in their choice of hard structure, resulting in uncertainty regarding the basic life history of this species. Because the Wabash River Blue Sucker population may be one of few surveyable populations with high abundance and successful reproduction, their demographics can provide a benchmark against which threatened populations can be compared. We harvested Blue Suckers (n = 168) …

Link Between Energy Investment In Biosynthesis And Cellular Resistance To Oxidative Insult: Test The Cost-Quality Hypothesis In Insects, Taiwo Bolanle Iromini

Masters Theses

“The metabolic cost of growth is the amount of energy invested to fuel the anabolic biochemical reactions of biosynthesis. It has been implicated in the efficiency of farm animals and fishes, thus, increased economic profit. The metabolic cost of growth in the cockroach nymph was reported to be 20-fold higher than that of the painted lady butterfly caterpillar. The cost-quality hypothesis was proposed to explain the extremely low biosynthesis energy cost in painted lady caterpillar when physiological and ecological processes the metabolic growth cost was attributed to could not. In this study, the cost-quality hypothesis was tested.

Midgut cells were …

Quantifying Effects Of Sleep Deprivation On Cognitive Performance, Quang Nghia Le

Masters Theses

“The most commonly used metric for evaluating alertness and vigilance is the Psychomotor Vigilance Test (PVT), previous studies have indicated that alertness and vigilance can be affected by the lack of sleep as a function of sleep loss. This study explores methods to predict median psychomotor vigilance reaction times. The data used in this study comes from a series of tests and surveys conducted on volunteer students. The data set contains many potential predictors of PVT and one aspect of the study was to identify variables that are useful in prediction. The performances of various prediction methods that allow for …

Performance Evaluation Of Alsi10mg Fabricated By A Selective Laser Melting Process, David Michael Murphy

Masters Theses

“Selective laser melting is becoming a widely used additive manufacturing technique that melts metal powder in a layer by layer process in order to build a desired part or geometry. Like many additive processes, selective laser melting allows for fabrication of parts with complex geometries. In order to fabricate a fully dense part there are a number of variables to take into account including: powder characteristics, laser parameters, and environmental parameters. Each of these variables can affect the microstructure and thus the mechanical performance of an additively manufactured part. In this work, the aluminum alloy AlSi10Mg was investigated. AlSi10Mg is …

Strain Partitioning Across The Polochic-Motagua Fault System In Guatemala: Insight From Kinematic Modeling, Qiaoqi Sun

Masters Theses

”The Polochic-Motagua Fault System in Guatemala is the on-land segment of the sinistral transform plate boundary between the North American Plate and the Caribbean Plate. Three major seismically active strike-slip faults in this fault system pose significant earthquake threats to surrounding populated cities. The assessment of seismic hazard requires a better understanding of the kinematics of the fault system. GPS monitoring indicates that seventy-five percent of the ~20 mm/yr. plate motion is accommodated by the Motagua Fault and less than twenty-five percent is accommodated by the Polochic Fault. However, the Polochic Fault documents a lateral offset of ~132 ± 5 …

Combining Laser Aided Ablation And Polishing To Minimize Surface Roughness Of Additively Manufactured Aluminium Components, Sahil Bipinkumar Patel

Masters Theses

“The surface roughness of additively manufactured parts is much higher than the acceptable range for most applications, thus post-processing is needed to qualify these parts for use. Laser polishing can be used to bring the surface roughness in an admissible range, but if the initial roughness is very high then the energy density for the polishing process needs to be very high to achieve a significant reduction in roughness. This high energy density can produce many process defects. Also, laser polishing alone cannot get rid of high wavelength asperities. Any waviness in the part can be linked with initial waviness …

Modal Analysis As Non-Destructive Testing Technique For Additively Manufactured 304l Stainless Steel Parts, Tristan N. Cullom

Masters Theses

“Non-Destructive Testing (NDT) methods for Additively Manufactured (AM) parts is an ongoing field of research in the additive community due to its ability to determine if a part can be deemed viable for field usage. This study presents modal analysis as a NDT method for AM parts. For production builds that have multiple copies of the same part, a correcting technique can be used such that the frequencies of the parts under test can be reliably compared against each other, which saves both time and money compared to other traditional NDT methods. This study was able to develop a novel …

Soil-Water-Energy Nexus Of Green Roofs, Katherine Ann Bartels

Masters Theses

"As the urban landscape continues to sprawl into previously undeveloped land to accommodate population growth, the need to design cities that effectively manage urban stormwater is imperative for a sustainable future. Green roofs use rain-harvesting techniques to reduce urban stormwater discharge while simultaneously providing traditional roof services as well as several ecosystem services. However, green roof media design varies greatly among commercial applications, and little guidance is available to engineers when selecting the media for prospective green roofs. Efforts to maximize stormwater retention and enhance urban heat island mitigation capabilities of green roofs while concurrently reducing nutrient loading were examined …

In-Situ X-Ray Imaging Of The Selective Laser Melting Process, Meelap M. Coday

Masters Theses

"Fusion-based metal additive manufacturing (AM) has garnered much interest in recent decades. Despite the popularity of fusion-based AM technologies such as selective laser melting (SLM), there are still fundamental questions and uncertainties that need to be addressed. In this work, we focus on the understanding of the undercooling in the SLM process and the uncertainties induced by the laser beam size, power, and scan speed. First, we report the estimation of undercooling in the SLM process from the solidification rate measured by in-situ high-speed synchrotron x-ray imaging, based on the dendrite growth velocity model. The undercooling changes as a function …

Attack Detection And Mitigation In Mobile Robot Formations, Arnold Fernandes

Masters Theses

"A formation of cheap and agile robots can be deployed for space, mining, patrolling, search and rescue applications due to reduced system and mission cost, redundancy, improved system accuracy, reconfigurability, and structural flexibility. However, the performance of the formation can be altered by an adversary. Therefore, this thesis investigates the effect of adversarial inputs or attacks on a nonholonomic leader-follower-based robot formation and introduces novel detection and mitigation schemes.

First, an observer is designed for each robot in the formation in order to estimate its state vector and to compute the control law. Based on the healthy operation of the …

Design And Development Of Power Processing Units For Applications In Electrically-Propelled Satellite Systems, Kartikeya Jayadurga Prasad Veeramraju

Masters Theses

"Electrospray technology provides a way to ionize specialized liquids by applying high voltages across a sharp porous tip and a metallic mesh. This technology is widely used in the field of mass spectroscopy for generating ions for testing purposes. The dawn of nano-satellites posed new challenges in the miniaturization of many conventional satellite sub-systems. One significant challenge faced in such a process was the miniaturization of the propulsion system. Electrosprays have started to find their application in the field of Aerospace Engineering and now are formally known as Electrospray Thrusters. These thrusters provide high specific impulse and are attractive substitutes …

Rhetorical Analysis Of Statements Of Purpose (Sps) For Admission To Graduate School: A Shared-Understanding Perspective Of The Sp Genre, Priyanka Ganguly

Masters Theses

"In this study, I analyzed twenty-four statements of purpose (SPs) submitted to the Department of English and Technical Communication at Missouri University of Science and Technology (Missouri S&T) by current and former students. My goal was to determine the applicants' shared understanding of the SP genre. I analyzed the SPs from three dimensions: rhetorical moves, rhetorical appeals (pisteis), and rhetorical style (elocutio).

To understand the rhetorical moves used by the applicants, I analyzed the content of their SPs according to the categories (moves) and codes (steps) validated in my pilot study. To understand the arguments used by the …

Computer Vision Based Deep Learning Models For Cyber Physical Systems, Muhammad Monjurul Karim

Masters Theses

“Cyber-Physical Systems (CPSs) are complex systems that integrate physical systems with their counterpart cyber components to form a close loop solution. Due to the ability of deep learning in providing sensor data-based models for analyzing physical systems, it has received increased interest in the CPS community in recent years. However, developing vision data-based deep learning models for CPSs remains critical since the models heavily rely on intensive, tedious efforts of humans to annotate training data. Besides, most of the models have a high tradeoff between quality and computational cost. This research studies deep learning algorithms to achieve affordable and upgradable …

Intrinsic Mechanical Properties Of Zirconium Carbide Ceramics, Nicole Mary Korklan

Masters Theses

“This research focuses on the processing and mechanical properties of zirconium carbide ceramics (ZrC_x). The first goal of this project was to densify near stoichiometric (i.e., x as close to 1 as possible) and nominally phase pure ZrC_x. The maximum stoichiometry achieved for the ZrC_x (C/Zr ratio of 0.92) was measured using gas fusion analysis. Hot pressing was used to obtain dense ZrC_x. Archimedes was used to determine the relative density of hot pressed ZrC_x at > 95%. Scanning electron microscopy (SEM) was used to determine the overall microstructure of the hot pressed …

Influence Of Input Energy On Mechanical Properties Of Laser Powder Bed Fused Aisi 304l Stainless Steel, Tan Pan

Masters Theses

“Powder Bed Fusion process with selective laser melting technique is popularly adopted in additive manufacturing area on account of its layer by layer manufacturing fashion capable of fabricating components with complex internal and external geometries and structures. However, the process-property map is unique and vital for different materials and AM configurations used for fabrication. The process parameter is identified as a significant factor that heavily influences the properties and performances of the printed materials.

Current work aimed to extend the existing knowledge on Laser Powder Bed Fusion fabricated AISI 304L by accessing the influence of varying energy input on the …

Inclusion Control In Steel Castings, Koushik Karthikeyan Balasubramanian

Masters Theses

“Non-metallic inclusions are mainly comprised of oxides, sulfides, and nitrides, and are formed in liquid steel during the melting and refining process, as a result of reoxidation, worn-out refractories, or entrained slag. The notch toughness of high strength steels is particularly susceptible to the type, number, size, and distribution of non-metallic inclusions. High manganese and aluminum austenitic steels, or Fe-Mn-Al steels, have gained much interest in the military and automotive sector because of their excellent combinations of high strength and toughness. However, these steels are subject to both oxide bifilms and aluminum nitride, AlN, inclusions which form during melting and …

Therapeutic Dna: Delivery And As A Delivery Vehicle, Natalie J. Holl

Masters Theses

"A review of gene delivery methods and gene editing methods, as well as original research utilizing DNA as a delivery vehicle is presented in the following thesis. Thousands of diseases have been linked to genes. Gene therapy, either delivering therapeutic genes or editing DNA bases, has arisen as a treatment option with the potential to cure diseases, rather than just ease symptoms. Genes and editing tools need to be delivered to cells for these therapies to be effective and many techniques have been developed to address the issue of delivery. Nonviral and viral methods have been used to deliver nucleic …

On The Investigation Of Hot Tearing Behavior Of Continuous Cast Steel, Yanru Lu

Masters Theses

”Hot tearing has long been recognized as a major problem that plagues the development of the continuous casting process and results in low-quality products. Understanding of the mechanisms and the required conditions for the hot tearing formation is important for industries but has not been well-established yet. Thus, this research focuses on the hot tearing issue observed in continuous cast steel, by providing a summary of the current research progress and then introducing a new laboratory method to determine the thermo-mechanical properties relevant to hot tearing of different steel grades under different solidification conditions. In this method, an apparatus was …

The Role Of Tectonic Inheritance, Plate-Reorganization, And Magma Flare-Ups In The Evolution Of The Sevier Orogeny, J. Daniel Quick

Masters Theses

"The temporal and spatial distribution of strain associated with the Sevier Orogeny in western North America is significantly different in the southern end of the belt, at the latitude of Las Vegas, than further to the north at the latitude of Salt Lake City. Until this study, reasons for these differences were speculative as a lack of thrust kinematic data in the intervening region hindered along strike correlation across the belt. A crystallization age of 100.18 ± 14 0.04 Ma was determined for zircons extracted from a recently recognized ash fall tuff near the base of the synorogenic Iron Springs …

The Application Of Machine Learning Models In The Concussion Diagnosis Process, Sujit Subhash

Masters Theses

“Concussions represent a growing health concern and are challenging to diagnose and manage. Roughly four million concussions are diagnosed every year in the United States. Although research into the application of advanced metrics such as neuroimages and blood biomarkers has shown promise, they are yet to be implemented at a clinical level due to cost and reliability concerns. Therefore, concussion diagnosis is still reliant on clinical evaluations of symptoms, balance, and neurocognitive status and function. The lack of a universal threshold on these assessments makes the diagnosis process entirely reliant on a physician’s interpretation of these assessment scores. This study …

Evaluation Of The Symbiotic Relation Between Endophyte And Poplar Trees Exposed To Landfill Leachate, Catalina Vega Hurtado

Masters Theses

“The contamination of soil and groundwater from leachate leakage from landfill has turned, nowadays, into a global public issue. One of the main concerns about this pollutant is the potential threat to human and ecosystem health. The current research studied endophyte bacteria in association with poplar trees (Populus sp.), as a method of bioremediation of landfill leachates. The objective of the project was to identify treatment strategies that may improve plant performance (survival rates, plant fitness, and degradation efficacy) with the purpose of being implemented in phytoremediation plots, aimed to intercept and treat landfill leachate, before the contamination of watershed. …