Digital Commons Network^™

Microcapsule Containing Lactic Acid Bacteria For Treatment Of Peptic Ulcers, Brandon Jerome Hinkel

Master's Theses

Probiotics are marketed throughout the world to promote the health of the consumer by improving the microorganisms that normally occur in the intestinal tract (Tannock, 1997). It has also been suggested that probiotics can prevent pathogen infections by adhering to the intestinal mucosa (Lee, Lim, Teng, Ouwehand, Tuomola, & Salminen, 2000). While probiotics can be delivered to the infected areas in multiple fashions, microencapsulation is a newer form of delivering probiotics straight to the infected area. A whey protein microcapsule is thought to protect the probiotics from stomach acid and delivers the treatment to the affected area. To ensure this …

Point Based Approximate Color Bleeding With Cuda, Nicholas D. Feeney

Master's Theses

Simulating light is a very computationally expensive proposition. There are a wide variety of global illumination algorithms that are implemented and used by major motion picture companies to render interesting and believable scenes. Every algorithm strives to find a balance between speed and accuracy. The Point Based Approximate Color Bleeding algorithm is one of the most widely used algorithms in the field today. The Point Based Approximate Color Bleeding(PBACB) global illumination algorithm is based on the central idea that the geometry and direct illumination of the scene can be approximated by using a point cloud representation. This point cloud representation …

Assessing Physiological Thresholds For Eelgrass (Zostera Marina L.) Survival In The Face Of Climate Change, Carolyn Jane Ewers

Master's Theses

Seagrasses are well known for the important ecological roles they play in coastal marine waters worldwide. However, the severe rate of decline observed in seagrasses this century is expected to accelerate with climate change. Conservation efforts can be improved by quantifying physiological thresholds of seagrasses and using these estimates in modeling to forecast changes in distribution. This study examines the response of eelgrass (Zostera marina L.) across current temperatures to look for early warning signs of vulnerability and to evaluate the ways we determine critical thresholds for survival. Whole eelgrass ramets, collected from three beds in Morro Bay, California, …

Re-Healable Coating Based Upon Thermally Responsive Linkages, Dahlia Ningrum Amato

Master's Theses

The goal of this thesis was to design thermally responsive polyol resins that would be compatible with isocyanates. Two approaches were made to reach this goal, the first involved functionalizing soybean oil and the second involved post-polymerization modification of a methacrylate based resin.

A soybean based coating with thermally responsive Diels-Alder linkages has been prepared following an automotive two-component formulation. The resulting coatings displayed the capability to be healed following physical deformation by a thermal stimulus, and such a material has significant potential for end users. Various curing agents were employed, and resulted in variation of scratch resistance and re-healablity. …

The Effects Of Age On Muscle Loss And Tissue-Specific Levels Of Nf-ĸb And Sirt6 Proteins In Rats, Tiev C. Laguire

Master's Theses

The objective of this study was to examine the influence of age on food intake, tissue and organ mass and NF-ĸB and SIRT6 levels in various tissues. The transcription factor, Nuclear Factor Kappa-B (NF-ĸB), is associated with both catabolic and anabolic pathways of muscle metabolism and may be involved in age-related muscle loss. SIRT6 is a member of the sirtuin family of proteins that function as protein lysine deacetylases and are associated with longevity in a number of organisms. Male Sprague-Dawley rats, aged 6 months (Adult) and 21 months (Old) were fed a commercially available diet for 10-17 days. Old …

Matrix Remodeling Accompanies In Vitro Articular Cartilage Spherical Shaping, Nathan Thomas Balcom

Master's Theses

Introduction: Articular cartilage (AC) is a low friction load bearing material found in synovial joints. The natural repair of damaged tissue is difficult and often requires surgical intervention. With large defects it becomes necessary to match the original tissue geometry. We hypothesized that localized collagen (COL) and/or proteoglycan (PG) remodeling occurs during AC spherical reshaping. The objective of this study was to determine the presence, magnitude and depth dependence of COL and PG remodeling that accompanies AC reshaping. Methods: Full thickness AC blocks (7x7 mm² surface area) were harvested from the ridges of the patellofemoral groove of immature (1-3 …

Improvement Of Electromagnetic Railgun Barrel Performance And Lifetime By Method Of Interfaces And Augmented Projectiles, Aleksey D. Pavlov

Master's Theses

Several methods of increasing railgun barrel performance and lifetime are investigated. These include two different barrel-projectile interface coatings: a solid graphite coating and a liquid eutectic indium-gallium alloy coating. These coatings are characterized and their usability in a railgun application is evaluated. A new type of projectile, in which the electrical conductivity varies as a function of position in order to condition current flow, is proposed and simulated with FEA software. The graphite coating was found to measurably reduce the forces of friction inside the bore but was so thin that it did not improve contact. The added contact resistance …

Characterization And Modeling Of An O-Band 1310 Nm Sampled-Grating Distributed Bragg Reflector (Sg-Dbr) Laser For Optical Coherence Tomography (Oct) Applications, Desmond Charles Talkington

Master's Theses

In this project, the performance aspects of a new early generation 1310 nm Sampled-Grating Distributed Bragg Reflector (SG-DBR) semiconductor laser are investigated. SG-DBR lasers are ideal for Source Swept Optical Coherence Tomography (SS-OCT), a Fourier-Domain based approach for OCT, necessitating a tunable wavelength source. Three internal sections control the frequency output for tuning, along with two amplifiers for amplitude control. These O-band SG-DBR devices are now being produced in research quantities. SG-DBR lasers have been produced at 1550 and 1600 nm for some times. Fundamental questions regarding the performance of the 1310 nm devices must be quantified. Standard metrics including …

Affine Image Registration Using Artificial Neural Networks, Pramod Gadde

Master's Theses

This thesis deals with image registration of MRI images using neural networks. Image registration combines multiple images of the same subject that were taken at different points in time, from different sensors, or from different points of views into a single image and coordinate system. Image registration is widely used in medical imaging and remote sensing. In this thesis feed forward neural networks and wavelet neural networks are used to estimate the parameters of registration. Simulations show that the wavelet networks provide significantly more accurate results than feed forward networks and other proposed methods including genetic algorithms. Both methods are …

Navy Seal Prosthetic Hand, Devon Patrick Augustus

Master's Theses

Prosthetic development recently has focused mainly on myoelectrically controlled electric hands despite a majority of upper extremity amputees actively choosing body powered devices. Myoelectric hands utilize a small electric pulse generated in muscles when flexing as a signal to the hand to close. Finger flexion in these devices is controlled by electromechanical servos, requiring no strength input from the user. Body powered devices use a cable attached to a shoulder harness which causes mechanical closure of the device via tension placed on a control cable by a shoulder shrug motion or arm extension. Outfitting of active duty service personnel has …

An Analysis Of Generational Caching Implemented In A Production Website, Marc E. Zych

Master's Theses

Website scaling has been an issue since the inception of the web. The demand for user generated content and personalized web pages requires the use of a database for a storage engine. Unfortunately, scaling the database to handle large amounts of traffic is still a problem many companies face. One such company is iFixit, a provider of free, publicly-editable, online repair manuals. Like many websites, iFixit uses Memcached to decrease database load and improve response time. However, the caching strategy used is a very ad hoc one and therefore can be greatly improved.

Most research regarding web application caching focuses …

Paris: A Parallel Rsa-Prime Inspection Tool, Joseph R. White

Master's Theses

Modern-day computer security relies heavily on cryptography as a means to protect the data that we have become increasingly reliant on. As the Internet becomes more ubiquitous, methods of security must be better than ever. Validation tools can be leveraged to help increase our confidence and accountability for methods we employ to secure our systems.

Security validation, however, can be difficult and time-consuming. As our computational ability increases, calculations that were once considered “hard” due to length of computation, can now be done in minutes. We are constantly increasing the size of our keys and attempting to make computations harder …

Applying Sustainability From A Systems Perspective:, Timothy Brophy

Master's Theses

Becoming sustainable is no longer an option. Current industry methods will not be able to support the necessary changes our growing society demands. In order to keep up with ever increasing demands industry will be aimed toward making major system changes toward a fully sustainable model. As of right now only basic sustainability actions have been put in place. Industry needs to make a strategic change toward resilient systems with an end goal of evolving into fully biomimic systems. This thesis covers a brief history of production leading to the Industrial Revolution which created a need for increased sustainability efforts. …

The Bicycle-Powered Smartphone Charger, Chris Arntzen

Master's Theses

This thesis entails the design and fabrication of a smartphone charger that is powered by a bicycle dynamo hub. In addition to the design and validation of the charger prototype, this thesis involves the testing and characterization of the dynamo hub power source, the design and construction of specialized test equipment, and the design and prototyping of a handlebar-mounted case for the smartphone and charging electronics. With the intention of making the device a commercial product, price, aesthetics, and marketability are of importance to the design. An appropriate description of the charger circuit is a microcontroller-based energy management system, tailored …

Seismic Rehabilitation Of Steel Concentrically Braced Frames Vulnerable To Soft-Story Failure Through Implementation Of Rocking Cores, Francisco Sanchez-Zamora

Master's Theses

Recent research reports that steel Concentrically Braced Frames (CBFs) (even the code-compliant ones) may be susceptible to soft-story failures during strong earthquakes. Such a failure mode causes catastrophic outcomes and should be definitely avoided in practice. This thesis focuses on development and validation of a seismic retrofit strategy for low-rise and mid-rise steel CBFs vulnerable to soft-story failures. The considered retrofit strategy consists of a sufficiently stiff rocking core (RC) pinned to foundation and connected to the existing frame. For demonstration purpose, two representative benchmark steel CBF buildings, which are the three-and six-story CBFs designed forLos Angelesin the SAC Steel …

Maternal Acculturation Levels And Their Effect On Children's Food Intake, Maternal Perceptions Of Body Size And Maternal Stress, Tracie A. Chavoor

Master's Theses

In the U.S., obesity has hit alarming rates and affects Hispanic children disproportionately. Acculturation, the shift from one culture’s values, beliefs and practices to those of a new culture, may have both negative and positive health effects on immigrants. The objectives of this study were to determine the association between the level of acculturation (low acculturation or high acculturation) of low-income Latina mothers and the foods consumed by their children (0 to 36 months old). The association between acculturation and maternal perceptions of infant and toddler body size, maternal perceptions of her own body size and maternal parenting stress were …

Bi-Directional Flyback Dc-Dc Converter For Battery System Of The Dc House Project, Austin J. Luan

Master's Theses

The DC House project strongly relies on renewable energy sources to provide power to the house for various loads. However, when these sources are unable to provide power at a certain time, a back-up energy source from a battery must be readily available to fulfill the house’s power needs. This thesis proposes a bi-directional flyback power converter to allow a single-stage power path to charge the battery from and to discharge the battery to the DC House 48 V system bus. The design, simulation, and hardware prototype of the proposed flyback bi-directional converter will be conducted to demonstrate its feasibility. …

Accurate Hardware Raid Simulator, Darrin Kalung Weng

Master's Theses

Computer data storage is growing at an astonishing rate. With cloud computing and the growth of the Internet enterprise storage has been predicted to grow at rates as high as 300\% per year. To fulfill this need technologies such as Redundant Array of Independent Disks or RAID are being used in industry today. Not only does RAID increase I/O performance but also provides redundancy measures to protect against hardware failure. Even though RAID has existed for some time now and is well understood, proprietary optimizations such as command scheduling and cache strategies that are employed by current RAID controllers are …

The Development Of An Electronic Data Collection Tool And Comparison Of The Electronic And Manual Methods Of Land Use Inventory, Wesley M. Catanzaro

Master's Theses

An important component of Planning Information Systems for municipal planning agencies is a comprehensive land use inventory that provides information on the location, distribution, and intensity of land uses throughout a community. This data is a necessary prerequisite for the informed creation of planning documents such as General Plans, Specific Plans, Housing Inventories, and Climate Action Plans. Beyond location, distribution and intensity of land uses, planners may also wish to incorporate additional information at the parcel level, such as the number of housing or commercial units, building condition, and/or access and connectivity to adjacent streets. Because some of this information …

Urban Agriculture Stormwater Management In California Cities, Rachel L. Cohen

Master's Theses

Cities within California are beginning to incorporate urban agriculture into their land use designations. Prompted by residents and local organizations, cities are hoping to capture the benefits that urban agriculture provides. Research has shown that urban agriculture renews and beautifies neighborhoods, provides healthy food choices, increases public health, has the potential to help with stormwater runoff, creates jobs, and fosters community. In the last few years, several California cities have made headlines as they have adopted new zoning codes that include urban agriculture.

In reviewing these new zoning codes and exploring the topic of urban agriculture, it became evident that …

San Luis Obispo Regional Transit Authority: Recommendations For Future Service Demand, Alexander J. Fuchs

Master's Theses

Transit agencies at all levels of government monitor trends in services, operations, and ridership using performance indicators. Federal and state agencies use these performance indicators in the appropriation of funds to transit agencies. Public transportation is subsidized through federal, state and local programs while only a portion of the operating expenses are covered through rider fares. In order to gather information on riders and travel patterns, transit agencies primarily focus on current transit riders, many of which are transit dependent populations. By definition, these populations use public transit services as the primary or only means of transportation. As a result, …

Comparing Class A Compressed Air Foam Systems (Cafs) Against Plain Water Suppression In Live Fire Gas Cooling Experiments For Interior Structural Firefighting, Sean Carter Mitchell

Master's Theses

Wildland fire services have successfully integrated compressed air foam systems (CAFS) into their fire suppression arsenal over the last few decades to effectively increase the firefighting ability of water. Many urban fire departments have done the same, but far more still rely on plain water to extinguish Class A fires. Many claims have been made about the advantages and disadvantages of firefighting foams, but only limited research has been conducted on the subject to date. Fire departments need more information, beyond that provided by foam suppliers and CAFS equipment manufacturers, to make an independent decision on whether or not to …

Eye "R" Glasses: Development Of An Infrared Sensor System For Detecting The Human Body, Rick Wong

Master's Theses

Throughout the years, sensors have been an integral part of automation, alert, and medical systems. Many of these systems measure physiological characteristics of the human body to alert themselves of their current conditions. Drowsy driver systems, for instance, measure the eyes and facial movements with a camera to determine if the driver is falling asleep at the wheel. Electroencephalography (EEG), electrooculography (EOG), and electromyography (EMG) employ electrodes on the human body to measure electrical activity of a patient’s REM sleep cycle patterns. Pulse oximeters use optical light through a process called photoplethysmography (PPG) to measure heart rate.

As diverse as …

A Multiphysics Simulation Of A Coronary Artery, Garry L. Howe

Master's Theses

This thesis hypothesizes that a commercially available multiphysics simulation software package can be easily employed to characterize the fluid flow and mechanical behavior in healthy and diseased arteries. To this end, multiphysics model of a coronary artery —the LAD artery—was created in COMSOL Multiphysics®. Wall shear stresses and distension were examined to validate the model. Such a model can be adapted to guide the design of cardiovascular devices.

Tracking Points On A Pacing Lead In A Beating Heart, Avinash Ramesh Varma

Master's Theses

Heart failure is a common condition during which the pumping action of the heart is affected because the heart does not contract or relax properly. Heart failure affects about 5 million Americans, with 550,000 new cases diagnosed each year. Cardiac resynchronization therapy (CRT) is used to treat symptoms and other complications associated with a heart failure. While performing CRT, Implantation of a pacing lead in the left ventricle of the heart is a very challenging surgical procedure performed with fluoroscopy. The target location is often difficult to reach through the tortuous coronary venous anatomy, which varies greatly among individuals. Placement …

Planning For A Coastal City: San Clemente's Local Coastal Program, Atousa Zolfaghari

Master's Theses

This professional project assesses current conditions and regulations within San Clemente’s Coastal Zone, and provides recommendations to the City and California Coastal Commission through a draft Land Use Plan. The amended Land Use Plan will be included in the certified Local Coastal Program, which will govern decisions that determine the short and long-term conservation and use of coastal resources within San Clemente’s Coastal Zone.

Local Coastal Programs (LCPs) are planning guides used by local governments for development within the Coastal Zone. They contain goals and policies for development and protection of coastal resources throughout coastal cities and counties in California. …

Getting Biologists To Drop Acid, Ryan Verdon

Master's Theses

Bioinformatics is the field of science in which biology, computer science, and information technology merge to form a single discipline. The ultimate goal of the field is to enable the discovery of new biological insights as well as to create a global perspective from which unifying principles in biology can be discerned. Bioinformatics involves the analysis of various types of data from multiple sources to create a model of a physical process found in the real world. To do the necessary modeling, data is being piled up in various different biological databases. So far this has worked relatively well. Unfortunately …

Greyfield Development In Vallejo, California: Opportunities, Constraints, And Alternatives, Jonathan Peter Atkinson

Master's Theses

Greyfield Development in Vallejo, California: Opportunities, Constraints, and Alternatives is a Project that determined that the regulatory framework and presence of underutilized commercial land make Vallejo, California the ideal community to facilitate Greyfield Development. The Project reviewed existing literature, determining that there are …

The City Of Morro Bay, California Sign Ordinance Update And Tourism-Oriented Directional Sign Plan, Erik Berg-Johansen

Master's Theses

ABSTRACT

The City of Morro Bay, California – Sign Ordinance Update and Embarcadero District

Tourism-Oriented Directional Sign Plan

Erik Berg-Johansen

This report includes a Draft Sign Ordinance, a Tourism-Oriented Directional Sign Plan, and a background report for each product. The final products were created thought a process involving extensive research, community outreach, and detailed discussions among City of Morro Bay staff.

The Sign Ordinance

It was discovered that signs are important to business owners and residents due to their effect on both economic and aesthetic issues in communities. This report documents research of scholarly articles, case studies, and community outreach …

Distribution Of Conflict Detection Of Aircraft For Next Generation Flight Management Systems, Scott H. Kuroda

Master's Theses

As the number of aircraft is expected to triple in the coming decades, the manual process used to safely route aircraft while in flight will become insufficient. There already exist work to algorithmically detect safe and unsafe routes between aircraft. This thesis extends that system such that the computation is distributed across multiple machines. In addition it also supports the detection of an unsafe route as it is actively modified by a third party. Furthermore, the system supports providing safe or unsafe route notification to multiple interested clients.