Digital Commons Network^™

Molecular Dynamics Of P21 And Fluorescent Sphingomyelin In Keratinocytes Exposed To Uvb, Tyler Malcolm Fraser

Master's Theses

Non-melanoma skin cancer (NMSC) is the most common malignant tumor, representing more than a third of all malignant tumors combined and the incidence is increasing every year. Ultraviolet (UV) radiation from the sun is the most dominant factor contributing to tumor initiation and progression. The condition is most prevalent in populations with lighter skin and older age. Current pharmaceutical molecular research targets the inhibition of the Epidermal Growth Factor Receptor (EGFR), a receptor which is commonly over-expressed or dysregulated in skin malignancies. This study evaluates the content and location of the damage marker p21 within keratinocytes that were incubated in …

Logging, Visualization, And Analysis Of Network And Power Data Of Iot Devices, Neal Huynh Nguyen

Master's Theses

There are approximately 23.14 billion IoT(Internet of Things) devices currently in use worldwide. This number is projected to grow to over 75 billion by 2025. Despite their ubiquity little is known about the security and privacy implications of IoT devices. Several large-scale attacks against IoT devices have already been recorded.

To help address this knowledge gap, we have collected a year’s worth of network traffic and power data from 16 common IoT devices. From this data, we show that we can identify different smart speakers, like the Echo Dot, from analyzing one minute of power data on a shared power …

A Computational Fluid Dynamics (Cfd) Analysis Of The Aerodynamic Effects Of The Seams On A Two-Dimensional Representation Of A Soccer Ball, Allen R. Rohr

Master's Theses

Most major sports today use a dedicated ball or projectile with specific shape, size, and surface geometry, except for soccer. Over the history of the sport, the surface geometry and design stayed relatively unchanged, sewn together using 32 pentagonal and hexagonal panels. However, recent innovations in panel designs differ substantially from the traditional 32 panel ball. The effects these new designs have on the aerodynamic characteristics of the ball have remained largely unknown, even with the influx of experimental research completed in the past decade. Experimental studies have been broad in scope, analyzing an entire ball in wind tunnels or …

A Carrier-Pigeon Uas For South Pole Data Transfer, Shaun P. Wixted

Master's Theses

The assessment of feasibility of an Unmanned Aircraft System (UAS) that is specifically tailored—in performance, operating and support characteristics, and payload—to support hardware-based data transfer from South Pole Station in Antarctica to a location of high connectivity has been undertaken. Due to the specific location of the Amundsen-Scott South Pole station and competing demands from other governmental agencies, satellite connectivity requirements for data transfers cannot be met at the South Pole. In the recent decades, the advancement in UAS capabilities have overwhelming extended their operational reach in military and commercial reconnaissance and surveillance missions. This UAS has the potential to …

Population Curation In Swarms: Predicting Top Performers, Ryan W. Heller

Master's Theses

In recent years, new Artificial Intelligence technologies have mimicked examples of collective intelligence occurring in the natural world including flocks of birds, schools of fish, and swarms of bees. One company in particular, Unanimous AI, built a platform (UNU Swarm) that enables a group of humans to make decisions as a single mind by forming a real-time closed-loop feedback system for individuals. This platform has proven the ability to amplify the predictive ability of groups of humans in realms including sports, medicine, politics, finance, and entertainment. Previous research has demonstrated it is possible to further enhance knowledge accumulation within a …

Increasing Algal Productivity And Treatment Potential In Raceways Fed Clarified Municipal Wastewater, Christopher D. Pittner

Master's Theses

Two sets of triplicate pilot algal raceway ponds (1000-L, 0.30-m deep, paddle wheel mixed) were operated for 14 months at a California wastewater treatment plant to treat wastewater and generate algal-bacterial biomass as biofuel feedstock. Two experiments were run to determine the effect on biomass productivity of (1) hydraulic residence time (HRT: 2, 3, 4, or 4.5 days) and (2) feeding schedule (18 small pulses during 8 AM-4 PM [diurnal] versus 20 large pulses during 4 AM-12 AM [diel]). The target productivity was at least 20 g volatile suspended solids per m2 of pond per day. Additional output variables were …

A Novel All Wheel Drive Torque Vectoring Control System Applied To Four Wheel Independent Drive Electric Motor Vehicles Utilizing Super Twisting And Linear Quadratic Regulator Methods, Kenneth Daniel Schmutz

Master's Theses

This thesis contains the design and simulation test results for the implementation of a new all-wheel drive (AWD) torque vectoring (TV) control system. A separate algorithm using standard control methods is included in this study for a comparison. The proposed controller was designed to be applied to an AWD independent drive electric vehicle, however the main concepts can be re-purposed for other vehicle drive train configurations. The purpose of the control system is to assist the driver in achieving a desired vehicle trajectory whilst also maintaining stability and control of the vehicle. This is accomplished by measuring various real time …

Bi-Stability In The Wakes Of Platooning Ahmed Bodies, Daniel M. Stalters

Master's Theses

Autonomous heavy vehicles will enable the promise of decreased energy consumption through the ability to platoon in closer formation than is currently safe or legal. It is therefore increasingly important to understand the complex and dynamic wake interactions between vehicles operating in close proximity for aerodynamic gains. In recent years, a growing body of research has documented a bi-stable, shifting wake generated behind the Ahmed reference bluff body. At the same time, studies of platooning Ahmed bodies have focused on changes to the body forces and moments at different following distances or lateral offsets, typically based around time-averaged measurements or …

Late Quaternary Evolution And Stratigraphic Framework Influence On Coastal Systems Along The North-Central Gulf Of Mexico, Usa, Robert Hollis

Master's Theses

Coastal systems in the Gulf of Mexico are threatened to reduced sediment supply, storm impacts and relative sea level rise (RSLR). The geologic record can provide insights of geomorphic threshold crossings (formation, progradation, transgression, destruction) to these forcing mechanisms to predict future barrier evolution to climate change. The stratigraphic framework and antecedent topography directly influence coastal evolution over geologic timescales. This study synthesizes ~2100km of geophysical data, 700+ sediment cores, and 63 radiocarbon dates to regionally map two sequence boundaries, multiple ravinement surfaces and fourteen depositional facies. One marine isotope stage (MIS) 6 valley’s fill provided up to 300 x10 …

The Effect Of Spill Contaminants On Marine Biofilms And Microbially-Induced Corrosion Of Carbon Steel, Rachel Mugge

Master's Theses

There are over 2,000 known historic shipwrecks located in the northern Gulf of Mexico which are ecological and cultural resources that support the diversity of life found in the deep-sea when they become artificial reefs. Spilled crude oil and chemical dispersant from the Deepwater Horizon (DWH) spill may have impacted the preservation of deep-sea historic shipwrecks and their microbiomes if they are located in areas where oil and dispersant were deposited on the seafloor. Oil potentially accelerates corrosion of metal through a biologically-mediated process called microbially-induced corrosion (MIC). Introduction of spill contaminants may accelerate MIC on shipwreck hulls, which may …

Influence Of Natural And Anthropogenic Environmental Variability On Larval Fish Diet, Growth, And Condition In The Northcentral Gulf Of Mexico, Angie Hoover

Master's Theses

The northern Gulf of Mexico experiences high levels of freshwater runoff annually from various sources including the Mississippi River and Mobile Bay, among other sources. Early life history stages of fishes are especially vulnerable to environmental variability created by freshwater discharge. The objectives of this study were to describe the available prey field, diet, growth and condition of larval fishes with respect to various effects of freshwater discharge in the northern Gulf. The first chapter compared these parameters in larval Gulf Menhaden (Brevoortia patronus) collected from three different water masses characterized by physical and biological parameters after the …

Determinants Of Team Resilience; The Role Of A Reset Process Across Conditions, Jeffrey Hanrahan

Master's Theses

No abstract provided.

Design And Fabrication Of Fdm 3d Printed Strain Sensors, Austin Smith

Master's Theses

As technology related to virtual reality, prosthetics, and robotics advances there appears a need for better sensor technology to augment these systems. In particular, many of the systems must interphase with the human body or the environment while maintaining large amounts of mobility and flexibility. This creates the demand for flexible electronics in particular flexible strain sensors to monitor movement. The work presented here explores the feasibility of commercially available elastic filament and desktop Fused Deposition Modeling (FDM) 3D printing as a simple and cost-effective route to develop flexible single-axis strain sensors. 3D printing allows for the rapid production and …

Metal Segregation During The Solidification Of Titanium-Aluminum Alloys For 3d Printing Applications, Jwala Parajuli

Master's Theses

Titanium-Aluminum alloys are one of the widely used alloys in multiple engineering applications. They are highly preferred in Selective Laser Melting (SLM) processes due to their low density, high melting temperature, and good strength. Segregation occurs during the solidification of most alloys and produces a non-uniform distribution of atoms. In SLM, segregation may depict the type of adhesion between the two deposited interfacial layers and the strength between the interphase between an already solidified layer and a new one, and overall, the quality of the printed part. In order to avoid segregation, the understanding of the segregation behavior at atomistic …

Measuring Liquefied Residual Strength Using Full-Scale Shake Table Cyclic Simple Shear Tests, Taylor R. Honnette

Master's Theses

This research consists of full-scale cyclic shake table tests to investigate liquefied residual strength of #2/16 Monterey Sand. A simple shear testing apparatus was mounted to a full-scale one-dimensional shake table to mimic a confined layer of saturated sand subjected to strong ground motions. Testing was performed at the Parson’s Geotechnical and Earthquake Laboratory at California Polytechnic State University, San Luis Obispo. T-bar penetrometer pullout tests were used to measure residual strength of the liquefied soil during cyclic testing. Cone Penetration Testing (CPT) was performed on the soil specimen throughout testing to relate the laboratory specimen to field index test …

Optimizing A Quantitative Real-Time Polymerase Chain Reactionprotocol For The Characterization Of Gene Expression In Blood Vesselmimics, Tristin Mcguffick

Master's Theses

Blood vessel mimics (BVMs) are tissue engineered blood vessels that are intended as an intermediate testing environment for intravascular devices, such as stents. Specifically, Cal Poly’s Tissue Engineering Lab hypothesizes that BVMs can be used to test endothelial cell and smooth muscle cell responses to existing and new vascular stents. Characterization techniques are required for BVMs to be accepted as a valid testing model, prior to being employed as an in vitro model to determine the effects of medical treatments. Quantitative real-time polymerase chain reaction (qPCR) is one available option for evaluating gene expression of tissues. qPCR can be performed …

A Numerical Study Of The Van Roosbroeck System For Semiconductors, Alan Ghazarians

Master's Theses

Since the 1950s, semiconductors have played a significant and daily role in our lives, as they are the foundation of our computers, phones, and other electronic devices. Aside from their obvious uses, the equations that govern semiconductors have peaked the interest of mathematicians and numerical analysts. In 1950, van Roosbroeck described the fundamental semiconductor device equations as a system of three nonlinear coupled partial di↵erential equations. The van Roosbroeck system poses a challenge numerically because of its strong nonlinearity and coupled equations. Its diculties lie in simultaneously solving drift-di↵usion equations for electrons and holes and using their solutions to solve …

Heat Transfer Interface To Graphitic Foam, Fang-Ming Lin

Master's Theses

The A Toroidal LHC ApparatuS (ATLAS) strip tracking detector is scheduled to be upgraded in 2025. The order of magnitude for the hit densities and the radiation damage are expected to increase. When radiation increases, the leakage current increases and the heat generated at the silicon trackers can lead to thermal runaway. Cooling is critical in these detectors.

In this study, a glassy graphitic foam was developed by AllComp Inc.~as a precursor to the adhesives (glues). Graphene\textsc{\char13}s highly anisotropic thermal properties result in high thermal conductivity in the planar direction, while it is low in the normal direction. In these …

Characterization Of Four Type-C Silica Columns Using Resveratrol Analogues, Joshua Topete

Master's Theses

High performance liquid chromatography (HPLC) is an analytical technique used to separate, identify and quantify components in a solution based on the affinities between analyte, mobile phase and stationary phase. The main goal of my research is to characterize four Type-C silica columns by comparing the retention of resveratrol analogues. The four columns included are functionalized with either Diamond Bidentate C18 (DBC18), Bidentate C18 (BC18), phenyl hydride or diol groups. Retention maps displaying mobile phase composition compared to compound retention times were compared between columns. In addition to this, two organic solvents (acetonitrile and methanol) were compared. Considering that the …

Numerical Studies Of Turbulence Effects In Cross-Flow Ventilation, Mina Mohammadmirzaei

Master's Theses

Natural ventilation systems reduce a building’s utilization of energy in terms of electricity consumption and fossil fuel usage. Many factors including building shape, window style and configuration, and wind turbulence impact the efficacy of natural ventilation. In order to investigate the effect of turbulence on natural ventilation, twelve different conditions of a cross-flow ventilated room were studied numerically using computational fluid dynamics. Wind tunnel studies of tracer gases in a scale model were used to validate the numerical results. A comparison of twelve investigated cases shows that air circulation inside a natural ventilated room is only slightly affected by turbulence, …

Autonomy In Video Games And Gamification, Jonathan Leventhal

Master's Theses

In the past decade, gamification (using game elements in non-gaming tasks to enhance motivation and engagement) has become a popular concept in many industries, but few studies have explored the principles under which it works. Self-determination theory suggests three psychological needs that gamification fulfills: competence, relatedness, and autonomy. Autonomy, a person's perception that they have the ability to act however they choose, has emerged as an important, yet less-studied aspect in gamification. Inclusion of autonomy in gamification should foster engagement, enjoyment, and better performance. An experiment inspired by the above was carried out in which a sample of college students …

Job Level And Job Family As Predictors Of Preferences For The Physical Environment, Rachel Smith

Master's Theses

Previous research shows that the physical work environment is related to various work-related employee outcomes. However, researchers have not focused on employee preferences for the physical work environment, nor predictors of such preferences. The current study proposed that job level and job family might predict employee preferences for the layout and design of work environments. The study also examined gender and age as moderators of the relationship between job level and employee preferences, and the relationship between job family and employee preferences. The results of online surveys from 157 employees of a medical technology company showed that job level predicted …

Prophecy For Sale: On American Rails, Erik Bryan White

Master's Theses

Prophecy for Sale: On American Rails follows the poetic tradition of Walt Whitman and Lawrence Ferlinghetti. This collection contains five numbered sections which show a progression of the human consciousness. Drawing on the works of Sylvia Plath, Weldon Kees, Jack Spicer, and others, the works in this collection exhibit a strong poetic American voice. Section “I: How Much Longer?” addresses class separation, racism, and inequality. Form mirrors content, confronting a world which seems bent on its own destruction. Section “II: The New Garden,” explores the human impact on nature in more detail and sets up solutions to the problems of …

The Effect Of Automating Routine Tasks On Air Traffic Controller Conflict Detection Performance, Lauren Claudatos

Master's Theses

The growing demand for air transportation necessitates the integration of automated support tools to assist air traffic controllers in managing the increase in number of flights. Using archival data from a human-in-the-loop simulation, the current study examined the potential consequence of integrating automated support on eight retired air traffic controllers’ performance and workload in current and projected future levels of air traffic. Two-way repeated measures ANOVA were used to examine workload and conflict detection performance across two levels of simulated air traffic density and two levels of automated routine task support. The participant controllers reported significantly higher workload and exhibited …

Modeling And Simulation Of Vehicle Performance In A Uav Swarm Using Horizon Simulation Framework, Adam J. Frye

Master's Theses

A UAV swarm is simulated using Horizon Simulation Framework. The asset utilized for the swarm agent is a simplified model of the MQ-1 Predator, a large fixed-wing aircraft. The simulated swarm utilizes a decentralized cooperative control approach to command the assets through the use of digital pheromones and a pheromone map. Each vehicle operates at steady-state flight conditions of 36 m/s with an altitude of 1,800 m, and utilize an LQR set-point controller to maneuver through the pheromone map. All pheromone and aircraft related models are written in Python to expand the HSF scripting capability and include airborne scenarios. The …

Effect Of Evapotranspiration Rate On Almond Yield In California, Dafne Isaac Serrano

Master's Theses

Since 2011, California has been under drought conditions. These conditions have not only affected water availability for farmers, but also production. California’s second most valuable crop, almonds, has been affected by drought conditions. This study used three models (Model 1-3) to describe almond yield variability from year to year and almond yield variability within a year in Kern County, CA. The study evaluated 185 almond farms that were classified in three locations (east side, west side and north west side). The years of the study were 2011 (wet year) and 2013-2015 (drought condition years). Model 1 determined a functional regression …

Mechanical Behavior Of Hybrid Concrete-Filled Fiber Reinforced Polymer Tube Columns, Samuel Turek

Master's Theses

Much of America’s infrastructure is in a state of disrepair. Many bridges are approaching or have passed their designed service life. Engineers and bridge owners have an obligation to rebuild back better. This can be achieved, in part, through the utilization of novel high performance structural systems. One such technology, the concrete-filled fiber reinforced polymer (FRP) tube (CFFT) system has been extensively studied the past few decades as an alternative design for bridge columns. This column system greatly simplifies construction by eliminating the need for column formwork and associated scaffolding. It also contributes to the confinement of the concrete, improving …

Understanding Spatiotemporal Growth Of Ride Source Services In New York City, Lorenzo Roland Varone

Master's Theses

Ride source is among the fastest growing services in the transportation sector. While the service initially served a niche market, ridership has boomed in recent years. Daily ride source pickups in New York City have increased from about 60,400 pickups in January 2015 to about 550,000 pickups in December 2017, an 810% increase. Even though ride source broke into the transportation landscape almost seven years ago, research studying its effects has been stunted by the limited open source data made available by TNCs. In order to help city officials make smart policy decisions regarding ride source, transportation experts must continue …

Sustainable Safety And The Decreasing Vulnerability Of Cyclists And Pedestrians In The Netherlands: Lessons For The United States, Vannesa Kello

Master's Theses

No abstract provided.

In Vitro Growth Of Osteoblasts On Poly Lactic-Co-Glycolic Acid Scaffolds Created Via Gas Foaming, Matthew James Thomas

Master's Theses

This study analyzed the feasibility of using gas foaming to create Poly Lactic-co-Glycolic Acid (PLGA) scaffolds for use as a substrate in bone tissue engineering and set out to determine whether the presence of osteoblasts on these scaffolds enhanced their material stiffness. The process of bone formation involves osteoblasts depositing extracellular matrix and calcifying this matrix with calcium phosphate crystals (Hasegawa et al., 2017) and pits between 30-40μm in diameter on tissue engineering scaffold surfaces have been shown to best promote osteogenic activity in the presence of bone-forming cells (Halai et al., 2014).The scaffolds were determined to contain pits within …