Digital Commons Network^™

Trapped In Endoderm-1 Reveals A Novel Role For Fruitless In Drosophila Melanogaster Courtship, Peter Luu

Master's Theses

Understanding how genes can direct behaviors has been a prevailing goal of neuroscience. Courtship in D. melanogaster is a complex yet stereotyped array of behaviors established by sex-specific genetic pathways mediated by sensory inputs by the nervous system. However, much remains to be discovered about the neurobiological and molecular mechanisms that regulate this complex set of behaviors. We have identified a group of cells expressing Trapped in endoderm 1 (Tre1) in which male Fruitless proteins are required to reduce the speed of courtship initiation. Tre1 encodes a G-protein-coupled receptor required for establishment of cell polarity and cell migration and has …

Cux2-Positive Radial Glial Cells Generate Diverse Subtypes Of Neocortical Projection Neurons And Macroglia, Ton Dan Nguyen

Master's Theses

The mammalian neocortex is 6-layered structure that develops in an “inside-out” manner, with cells of the deep layers (Layers 5-6) born first. Cells of the superficial outer layers (Layers 2-4) are generated subsequently and must migrate past older born cells to their final laminar position. Pioneering transplant studies suggested a progressive lineage restriction model, which posits that early neural stem cells (or radial glial cells, RGCs) are multipotent and sequentially generate different types of cortical neurons based on birthdate. Recently published work from Franco et al. (2012) argues against this paradigm, and proposes the existence of a subclass of neural …

Wilderness State Park Volunteers: A Qualitative Case Study Of Meaning And Sustainability, Christina A. Peterson

Master's Theses

In an increasingly urbanized world, parks, open space and wilderness areas are vitally important to human well-being. California State Parks provide people with the ability to connect with nature and engage in outdoor recreation. Moreover, these parks protect natural and cultural resources and preserve biodiversity. California State Parks are underfunded and rely on volunteers to support essential park services. The Wilderness State Park Uniformed Volunteer Program provides essential recreation, resource protection, and biodiversity services. In order to determine the elements of the volunteering experience that contribute to a strong sense of volunteer identity and meaning, a qualitative case study was …

Localization And Investigation Of Secondary Metabolite Producing Styela Clava-Associated Streptomyces Bacteria, James Demayo

Master's Theses

Natural products and natural product derivatives comprise some of the most successful drugs to date. Many natural products derive from the secondary metabolite profiles of high GC content actinomycete bacteria of the genus Streptomyces, which are sometimes associated with eukaryotic hosts. Identification of biosynthetic gene sequences for natural product secondary metabolites in Streptomyces can assist in isolation of the identified natural product. Moreover, the biosynthetic pathways of drug-like secondary metabolites derived from Streptomyces bacteria often provide insight into the available metabolites that can be produced. As a result, identification of bacteria capable of producing antibacterial products, including Streptomyces, …

With A National Park Next To Its Downtown: Forecasting The Distribution Of The Economic Impacts Of The Coltsville National Historical Park Within Hartford, Connecticut, Dmitriy V. Tarasov

Master's Theses

In late 2014, the Coltsville Historic District in Hartford, Connecticut, became a unit of the National Park Service. The new Coltsville National Historical Park encompasses the former Colt firearms factory and the adjoining remnants of the company-built township, informally known as Coltsville. Although best-known for producing some of the first practical multiple-shot firearms, the factory’s possibly greater significance lies in the various mass-production techniques using interchangeable parts that were pioneered there in the 19^th century.

Hartford, like many older American cities, has had to contend with both deindustrialization and suburbanization in recent decades. The push for national park status …

The Influence Of Resting Blood Pressure On Muscle Strength In Healthy Adults, Adam R. Blanchard

Master's Theses

No abstract provided.

A Replication-Inducible Recombinant Vaccinia Virus System To Conditionally Transcribe The Entire Human Rhinovirus C Genome, Zhixin Jing

Master's Theses

No abstract provided.

Assessing The Impact Of Breastfeeding Cessation On The Reported Incidence Of Diarrhea In Infants Between The Ages Of 7 To 12 Months: A Secondary Data Analysis, Ana Francisca Diallo

Master's Theses

Background: Diarrheal diseases remain a major cause of childhood morbidity in the United States. Optimal breastfeeding has been identified as one of the most effective measure to prevent diarrheal diseases in childhood.

Purpose: To evaluate the impact of breastfeeding duration during the first 6 months on the incidence of diarrhea in infants between 7 and 12 months in the United States.

Method: A secondary data analysis was performed using mothers and infants participating in the Infant Feeding Practices Study II (2005-2007).

Results: Compared to those who breastfed for 6 months or more, infants who discontinued breastfeeding between 0 …

Identification Of Agricultural Land Use In California Through Remote Sensing, Todd Allen Robinson

Master's Theses

Ground truthing actual crop types in an area can be expensive and time-consuming. The California Department of Water Resources attempts to ground truth land use in each county in California every five years. However, this is limited by budgetary constraints and often results in infrequent (more than every ten years) surveying of many counties. An accurate accounting of crops growing in a region is important for a variety of purposes including farm production estimates, groundwater and surface water modeling, evapotranspiration estimation, water planning, research applications, etc. Agricultural land use is continually changing due to development and environmental factors.

Currently, USDA …

Scaled Synthetic Aperture Rader Development, Jason Garvey Schray

Master's Theses

Several previous Cal Poly thesis projects involve synthetic aperture radar (SAR), automatic target recognition (ATR), and tracking. SAR data was either accessed from a publicly available database or generated using complex computer modeling software. The motivation for this dual thesis project is to design and construct a scaled SAR system to support Cal Poly radar projects. Ideally this is a low-cost, high resolution SAR architecture that produces raw range Doppler data for any desired target area. To that end, a scaled SAR system was successfully designed, built, and tested. The current SAR system, however, does not perform azimuthal compression and …

A Comparison Of Solvent And Water-Borne Alkyd Coatings And The History Of Voc Regulations In The United States, Molly Elise Burns

Master's Theses

A Comparison of Solvent and Water-Borne Alkyd Coatings Abstract

Conventional solvent based alkyd coatings have gone out of favor due to concerns over volatile organic compound (VOC) content. However, due to recent focus on renewable raw materials, alkyds are making a comeback in waterborne form. Water based alkyd coatings are known to have poor shelf stability and corrosion resistance, as well as other problems during the formulation process. This project focused on comparing solvent borne to two types of water-borne alkyds, water reducible alkyds and alkyds emulsions. The purpose was to understand the differences between the three types of alkyds …

A Comparison Of Wavelet And Simplicity-Based Heart Sound And Murmur Segmentation Methods, Joshua David Korven

Master's Theses

Stethoscopes are the most commonly used medical devices for diagnosing heart conditions because they are inexpensive, noninvasive, and light enough to be carried around by a clinician. Auscultation with a stethoscope requires considerable skill and experience, but the introduction of digital stethoscopes allows for the automation of this task. Auscultation waveform segmentation, which is the process of determining the boundaries of heart sound and murmur segments, is the primary challenge in automating the diagnosis of various heart conditions. The purpose of this thesis is to improve the accuracy and efficiency of established techniques for detecting, segmenting, and classifying heart sounds …

Pharaonic Occultism: The Relationship Of Esotericism And Egyptology, 1875–1930, Kevin Todd Mclaren

Master's Theses

The purpose of this work is to explore the interactions between occultism and scholarly Egyptology from 1875 to 1930. Within this timeframe, numerous esoteric groups formed that centered their ideologies on conceptions of ancient Egyptian knowledge. In order to legitimize their belief systems based on ancient Egyptian wisdom, esotericists attempted to become authoritative figures on Egypt. This process heavily impacted Western intellectualism not only because occult conceptions of Egypt became increasingly popular, but also because esotericists intruded into academia or attempted to overshadow it. In turn, esotericists and Egyptologists both utilized the influx of new information from Egyptological studies to …

Analysis Of Machine Learning Classifier Performance In Adding Custom Gestures To The Leap Motion, Eric Yun

Master's Theses

The use of supervised machine learning to extend the capabilities and overall viability of motion sensing input devices has been an increasingly popular avenue of research since the release of the Leap Motion in 2013. The device's optical sensors are capable of recognizing and tracking key features of a user's hands and fingers, which can be obtained and manipulated through a robust API. This makes statistical classification ideal for tackling the otherwise laborious and error prone nature of adding new programmer-defined gestures to the set of recognized gestures.

Although a handful of studies have explored the effectiveness of machine learning …

A 3-D Multiplex Paper-Microfluidic Platform, Mitchell Patrick Young

Master's Theses

3-D paper-based microfluidic devices (micoPADs) are small and portable devices made out of paper that offer a promising platform for diagnostic applications outside of a laboratory. These devices are easy to use, low cost, require no power source, and capable of detecting multiple targets simultaneously. The work in this thesis demonstrated the ability of a 3-D paper-microfluidic platform to simultaneously detect 5 targets. Rubber cord stock was used in conjunction with an acrylic housing unit to apply pressure along the edge of the channel. The indirect pressure application was successful in promoting vertical fluid flow between layers. Average channel development …

Cyberbullying Among Young Adults: Effects On Mental And Physical Health, Brett M. Goshe

Master's Theses

No abstract provided.

Ecological Risks And Benefits From The Novel Crop Camelina Sativa (L.) Crantz (Camelina), Richard C. Rizzitello

Master's Theses

It is important to fully understand the ecological implications of introducing new crop species and genetic traits because of potential hazards such as changes in native plant populations or the establishment of aggressive weeds. Conversely, the introduction of new crops and traits could provide ecological benefits such as providing pollen and nectar forage for pollinators. Camelina sativa (camelina or false flax) is an oilseed crop that is being genetically engineered (GE) for the production of biofuel, bioplastics, and dietary supplements for humans and animals. Relatively little scientific information exists about camelina cultivation, reproductive biology, and ecology. The primary research goals …

Preventive Health Care Among Immigrant Sudanese Women In The Greater Hartford Area Of Connecticut, Fawatih Y. Mohamed-Abouh

Master's Theses

No abstract provided.

Association Of The Dietary Inflammatory Index With Metabolic Syndrome In The National Health And Nutrition Examination Survey (2001-2006), Genevieve C. Caron

Master's Theses

Metabolic syndrome currently affects one third of adults in the U.S. and has been associated with a variety of chronic diseases that pose a burden to the nation. ^1,2 In the nationally representative NHANES dataset (2001-2006), dietary inflammatory index scores were found to significantly predict metabolic syndrome outcome among individuals above the age of 50 (OR=1.088; 95% CI=1.014-1.167; p=0.0184). Individuals older than 50 years of age who consume diets very high inflammatory properties were found to be 2.14 times more likely to have metabolic syndrome than those who consume a diet with very low inflammatory properties. This study supports the …

Characterizing Headwater Stream Hydrology And Nitrogen Export During Storms Across A Gradient Of Watershed Development, Jason Sauer

Master's Theses

Nitrogen (N) is a critical element for aquatic ecosystem function that can degrade water quality and cause eutrophication if in excess of natural levels. Anthropogenic nonpoint sources contribute more than 90% of total N added to major watersheds in the U.S, in excess of natural levels, and they are increasing with land development. Storms mobilize N from anthropogenic sources and generate periods of high N export to aquatic ecosystems. In this thesis, I explore how a gradient of watershed development affects the volume-weighted load, composition, and timing of N exported from first-order streams in New England during storms. I find …

Overtime Work Hours, Health Behaviors And Health Outcomes For Correctional Officers: An Examination Of Moderated Effects, Diana C. Tubbs

Master's Theses

Most of the existing research on corrections officers (COs) has focused on stress and burnout as well as the organizational factors that contribute to these outcomes. Recent studies have also revealed that COs are more likely to be obese and hypertensive than the general population. Studies not specific to corrections provide evidence that overtime hours are associated with poor employee health, and the present study aimed to address this general lack of research on the potential health impacts of overtime hours for COs. More specifically, this study investigated whether the effect of healthy behaviors on health and wellness outcomes changed, …

Childhood Obesity Prevention In Income-Disadvantaged Populations: An Evaluation Of Two Novel Approaches, Kayla L. Vosburgh

Master's Theses

No abstract provided.

Chemosensory Function In Chronic Smokers: Findings From Nhanes 2011-2014 And An E-Cigarette Intervention, Sarah-Grace Glennon

Master's Theses

No abstract provided.

The Self Relevance Of Stigma: The Impact Of Weight Stigma On Normal Weight Women's Health Cognitions, Paige Martinez

Master's Theses

Previous research has demonstrated that weight stigma is associated with negative health outcomes among women who are overweight; this effect has been shown in both experimental and longitudinal studies. However, normal weight women do not tend to experience negative health impacts from exposure to weight stigma. This study attempted to manipulate the self-relevance of weight stigma among 150 normal weight women, in order to test whether self-relevance of stigma has an impact on health cognitions. Limited support for this framework was found.

Perceived Self-Efficacy And Financial Incentives: Factors Affecting Health Behavior And Body Weight In Individuals With Overweight And Obesity, Julia Ann Simon

Master's Theses

No abstract provided.

Understanding How Intentionally Unplugging From Cell Phones Shapes Interpersonal Relationships And The Undergraduate College Experience, Jadelin P. Felipe

Master's Theses

The purpose of this study was to gain an understanding of what motivated college students—the Unplugged Students—to intentionally use their cell phones less and how they understood the impact that unplugging had on their interpersonal relationships and college experience. Nine undergraduate college students from four private schools were interviewed in one-on-one semi- structured interviews. These students, considered non-users, provided a particularly useful perspective as these students made a conscious choice to counteract social norms and experienced both being plugged in and unplugged. Cell phones and the act of unplugging proved to make up a complex and more nuanced topic than …

Investigating Unit Stream Power And Drainage Capture In The Upper Dajia River, Taiwan Using Geomorphic Indices, Lindsey C. Belliveau

Master's Theses

No abstract provided.

Micro-Grid Reliability Modeling And Analysis Approaches, Xiaofang Shi

Master's Theses

Micro-grids are becoming of more interest worldwide to achieve reliable electrical energy infrastructure during natural hazards and catastrophic situations due to their ability to operate in both grid-connected and islanded modes. They typically include distributed generation resources that could provide heat and electricity and are expected to have significant clean energy penetration.

Micro-grid system reliability is critical for system design and maintenance since it is commonly used as a backup power system especially during the main grid blackouts or failures. The study of micro-grid reliability can give system designers, operators, and customers potential failure modes of its subsystems and components …

The Mediterranean Diet And Cardiovascular Disease: A Multilevel Meta-Analysis, Julia E. Shook

Master's Theses

No abstract provided.

A Physiologically Motivated Approach To The Classification Of Natural Sounds Using High Order Sound Statistics, Brian B. Bishop

Master's Theses

The ability of humans and animals to classify sounds into behaviorally relevant categories is an ongoing field of study in auditory neuroscience and psychophysics. We employed a physiologically motivated signal processing scheme to extract time-varying statistics from a large database of real sounds. Our hypothesis is that two sound statistics, intensity and contrast, will be sufficient to classify broad categories of sounds using a naïve Bayesian classifier. We seek to evaluate this hypothesis, determine to what extent these two time-varying statistics can be used to classify sounds and to evaluate the limitations of the technique. The sounds themselves were organized …