Digital Commons Network^™

Reconstitution Of Munc18-Dependent Mast Cell Degranulation, Matthew Grant Arnold

Master's Theses

Mast cells are specialized secretory leukocytes that play diverse roles in the body, mediated by release of histamine and other pharmacologically active substances. Although offering essential protection in innate and adaptive immunity, mast cells are also essential to the progression of inflammatory diseases, including allergy and asthma, (Theoharides et al., 2012). Exocytosis of pro-inflammatory mast cell mediators in response to otherwise innocuous antigens relies on evolutionarily-conserved membrane fusion machinery. These proteins, called SNAREs are regulated by the Sec1/Munc18 (SM) protein family (Axle Lorentz, Baumann, Vitte, & Blank, 2012). Mast cells express three mammalian Munc18 isoforms (a, b, and c), which …

An Electrolytic Method For Tartrate Stabilization In Chardonnay Wine, Michael Vincent Chen

Master's Theses

Tartrate stabilization is the process that removes components that contribute to the crystallization of potassium hydrogen tartrate (KHT) and calcium tartrate (CaT) which is an undesirable outcome for wine quality. There are a variety of current tartrate stabilization techniques such as cold stabilization, chemical additives, ion exchange resins, and electrodialysis that stabilize wine, but the most popular being cold stabilization. Cold stabilization requires high amounts of energy and resources to stabilize wine. With the ever increasing demand for more efficient processing, an alternative tartrate stabilization technology based on an electrolytic method was developed and its viability to stabilize wine was …

The Effects Of A Uniformly Weighted Exercise Suit On Biomarkers Of Bone Turnover In Response To Aerobic Exercise In Postmenopausal Women With Low Bone Density, Haley Frances Terndrup, Alison K. Ventura, Todd Hagobian, Scott Hazelwood

Master's Theses

Current options for maintaining or slowing aging-related bone mineral density (BMD) loss in postmenopausal women primarily include pharmaceutical agents. More recently, physical activity and exercise have been suggested as highly effective, low cost alternatives. Weighted aerobic exercise, utilizing load carriage systems (LCS), is known to increase the gravitational forces impacting bone, creating a higher osteogenic stimulus than standard aerobic exercise. In response to the positive research on aerobic exercise with well-designed LCS, Dr. Lawrence Petrakis, MD, developed a unique 5.44 kg uniformly weighted exercise suit. This study aimed to examine the effects of the uniformly weighted exercise suit on serum …

Effects Of Extended Spaceflight On The Mandible And Incisor Teeth Of Mice, Didem Dagdeviren

Master's Theses

No abstract provided.

The Interrelations Between Work Factors, Family And Work Health Climate, Work Schedule, And Individual Behaviors, Jennifer C. Buden

Master's Theses

Background: The rates of obesity in the United States continue to rise, particularly with disparities in high stress, low job control occupations such as corrections. Employers are in a unique position to improve employee health through development of Total Worker Health interventions that integrate worker safety and health promotion to improve employee health and well-being.²⁵ Understanding influences on health behaviors in the workplace such as social support, and work schedules as well as family environment, may aide in developing worksite preventive strategies with the anticipation of chronic disease reduction and weight management. Purpose: The purpose of these studies was …

A Clinical Trial To Investigate Digital Gingivitis Image Analysis Method And Examiner-Based Grading In Assessing Experimental Gingivitis, Liliana E. Aranguren

Master's Theses

A Clinical Trial to Investigate Digital Gingivitis Image Analysis Method and

Examiner-Based Grading in Assessing Experimental Gingivitis

Liliana Aranguren D.D.S

University of Connecticut, 2016

Objective: To compare a Digital Gingivitis Image Analysis (DGIA) method and examiner-based gingival grading in assessing experimental anterior gingivitis.

Methods: This was a single-center, examiner-blinded, parallel-group, randomized clinical trial. The study had 49 subjects and consisted of 2 phases: 2 weeks Oral Hygiene phase and 3 week induced gingivitis phase (days 0-21). During the hygiene phase, subjects received oral prophylaxis and used an electric toothbrush toothbrush. At day 0 of the Induced Gingivitis phase, 25 patients …

Study Of Rehydration Properties Of Powder Produced From Chelated Skim Milk, Kristina Ellice Tan

Master's Theses

Poor rehydration properties of skim milk powder (SMP) can impact processing efficiency and functionality in finished product applications. Rehydration can be split into four stages: wettability, sinkability, dispersibility, and solubility. Previous work has suggested that chelator addition during SMP manufacture leads to higher solubility compared to SMP without chelators. This study focuses on the addition of ethylene diamine tetraacetic acid (EDTA) or sodium citrate dihydrate (SCD) at concentrations of 5, 10, and 15 mM to skim milk prior to evaporating and spray drying. The objective of this investigation was to determine the effects of the chelator additions on each SMP …

The Impact Of A Smarter Lunchrooms Makeover On Children's Food Choice And Consumption, Polina Zhuzhina

Master's Theses

Childhood obesity has tripled over the past three decades and poses a serious public health problem. The Smarter Lunchrooms Movement aims to increase healthy eating by incorporating low-cost to no-cost alterations to the school lunchroom in an effort to increase consumption of healthier foods, such as fruits and vegetables, by making them more attractive and convenient.

Our study implemented Smarter Lunchrooms interventions at two primarily Hispanic elementary schools in Paso Robles, CA. The interventions focused on increasing the appeal of the salad bars, including installation of age-appropriate signage highlighting fruits and vegetables, as well as branding of fruits and vegetables …

The Use Of Lactic Acid Bacteria To Control The Growth Of Foodborne Pathogens On Fresh-Cut Fruits And Sprout Vegetables, Franca Gabriela Rossi

Master's Theses

Growing consumer awareness of the health benefits associated with fruits and vegetables and demand for easy to prepare products has prompted the development of a wide variety of minimally processed fruits and vegetables. Minimally processed fruits and vegetables are often peeled, cut, or diced which compromise the produces’ natural protective barriers, exposing a nutrient rich medium and providing an ideal environment for the growth of microorganisms, including foodborne pathogens. The germination conditions of sprout vegetables consisting of relatively high temperatures and humidity, low light and abundance of nutrients are also conducive to the proliferation of foodborne pathogens. Recent outbreaks and …

Influence Of Chelating Agents On Proteolysis Of Micellar Casein Slurries, Azucena Becerril Diez

Master's Theses

ABSTRACT

Influence of chelating agents on proteolysis

of micellar casein slurries

Azucena Becerril Díez

The focus of this research was to analyze the effect of Ca chelators on the proteolytic activity of rennet during ripening of a micellar casein slurry. This research was divided in two phases. During the first phase, preliminary studies were performed to understand the behavior of rennet and the milk system in the presence of chelating agents. A solution of reconstituted skim milk at 10% (w/v) was prepared. Individual samples of this solution were divided in two study groups, samples with chelators and rennet and samples …

Effects Of Bisphenol-A And Styrene On Fertilization And Development Of The Purple Sea Urchin (Strongylocentrotus Purpuratus), Nicole C. Uibel, Nikki L. Adams, Jennifer Carroll, Sean Lema

Master's Theses

Plastic waste and debris have greatly increased in the marine environment during the past 50 years. Not only do these plastics entangle and get ingested by marine mammals, turtles, and sea birds, but they also leach chemicals, such as bisphenol-A (BPA) and styrene into the aquatic environment. While some of these chemicals are known to be toxic, few studies have examined their effects on broadcast spawning marine invertebrates, specifically at environmentally relevant concentrations. Purple sea urchins, Strongylocentrotus purpuratus, from the central coast of California, were utilized to examine effects of BPA and styrene on fertilization success and early development of …

Removing Oil From Fried Foods Via Mechanical Process, Yufay Chow-Yee

Master's Theses

Fried foods are delicious and enjoyed by almost everyone. However, they are not the healthiest foods to eat because of the amount of oil they contain. This thesis, sponsored by Moaero Company founder, Mr. Harrish Bhutani, intends to determine whether a simply designed centrifuge system can remove a reasonable amount of oil from fried foods after it has been deep fried without adversely affecting the texture of the fried food. Due to a large variety in the texture as well as the type of fried foods, and in order to keep the scope of this thesis more focused and feasible, …

After The Paris Agreement: How India Can Use Climate Financing To Implement A Sustainable Clean Cookstove Program, Hannah Kornfeld

Master's Theses

The burning of biomass for cooking purposes without proper ventilation and filters poses a massive health and climate risk. Health implications from exposure to household air pollution from this type of fuel impacts women and children in many developing countries, who spend many hours a day cooking and gathering fuel. Climate implications from burning solid biomass results in increased carbon dioxide and black carbon emissions, which contribute to global climate change. This thesis aims to explore the issues associated with biomass cookstoves in terms of both health and climate, and seeks to understand how a new national clean cookstove program …

The Influence Of Exclusive Breastfeeding On Growth Trajectory From Birth To Year 5 In A Wic Cohort, Lindsey Arevalos

Master's Theses

OBJECTIVE. The impact of exclusively breastfeeding (EBF) on child body mass index (BMI) from birth through 60 months of age was investigated.

METHODS. 60,190 mothers and children attending Women, Infant and Children (WIC) clinics in the Santa Barbara and San Luis Obispo counties of California provided data on breastfeeding duration, maternal pre-pregnancy BMI, and child weight-for-length (WL) was measured at 3 month intervals until 5 years of age. Missing time points were interpolated in determining child BMI/WL z-score trajectories plotted on the Center of Disease Control (CDC) infant and child growth curves. Multivariate analysis of variance was used to contrast …

The Bottlefly Ios Application For Wine Recommendations, Carson James Carroll

Master's Theses

The use of smartphone applications has taken over the way people interact with the world. The design of an application has become an important aspect in keeping the user engaged [22]. People are looking for applications that are easy to use and will get the job done. This thesis focuses on the design of a mobile application for iOS that recommends wine in various retail locations that match a user’s taste preferences.

The goals of this thesis are to design an iOS application that recommends wine to consumers, improve upon the wine recommendation algorithms by acquiring more customer data, and …

Assessment Of Micronutrient Status In Pregnant Malawian Women Before And After Treatment For Moderate Malnutrition, Cambria M. Glosz

Master's Theses

Background: Multiple micronutrient deficiencies are prevalent in pregnant women in developing countries and can result in adverse effects to both the mother and infant. Multiple micronutrient supplements or supplementary foods may be a way to combat micronutrient deficiencies.

Objective: To assess change in micronutrient and protein levels in moderately malnourished pregnant Malawian women after receiving one of three nutritional interventions.

Methods: Serum retinol, 25-hydroxyvitamin D, ferritin, vitamin B₁₂, folate, zinc, albumin and C-reactive protein concentrations were measured in pregnant women with MUAC >20.6 cm and

Results: Baseline micronutrient concentrations indicated high rates of deficiency …

Comparison Of Foaming Properties Between Chelated Reconstituted Smp And Caseinates, Boya Liu

Master's Theses

Caseinate powders have been well accepted because of their foaming properties. In this study, 10% solution of reconstituted skim milk powder (SMP) chelated with sodium hexametaphosphate (SHMP) and trisodium citrate (TSC) at 1 mEq, 50 mEq, and 100 mEq were prepared to conduct a comparison with sodium caseinate, potassium caseinate, and calcium caseinate solutions. Foamability, foam stability as well as the preferential locations of αs-casein, β-casein and !-casein in their foams were analyzed. It was hypothesized that the foamability, foam stability and the preferential locations of these three caseins in the milk foams are different from treatment to treatment. Milk …

Intercolony Comparison Of Diets Of Western Gulls In Central California, Anne L. Cassell

Master's Theses

As human populations expand, they force free-ranging animals to adapt to an increasingly urban environment, resulting in changes in diets, reproductive success, and mortality. The diets of two western gull (Larus occidentalis) breeding populations in central California were compared. One colony, Año Nuevo Island (ANI), is 1 km from shore and within 30 km of a municipal landfill. The other colony, Southeast Farallon Island (SEFI), is located 45 km off the shore of San Francisco, CA. Given the proximity of ANI to the shore and the landfill, I predicted that gulls from ANI would have more garbage in their diets. …

Behavioral Determinants Of Biofortified Food Acceptance: The Case Of Orange-Fleshed Sweet Potato In Ghana, Chinonso E. Etumnu

Master's Theses

Biofortified foods are being introduced in sub-Saharan Africa as an important strategy to help address micronutrient malnutrition. However, there has been little research on factors that could play decisive roles in their successful introduction. This paper investigates the determinants of consumer acceptance of biofortified orange-fleshed sweet potato (OFSP) using data from a choice experiment conducted in Ghana. I find that OFSP is preferred to traditional white-fleshed and yellow-fleshed sweet potatoes as indicated by consumers' marginal willingness to pay for the three varieties. I also find that respondents' socio-economic characteristics do not have a significant effect on consumer acceptance of OFSP. …

Climate Variability Influences Women’S Attitudes Towards Intimate Partner Violence (Ipv), Jean Lee

Master's Theses

The World Health Organization (WHO) estimates 1 in 3 women worldwide has experienced violence against women. Our study examines the effects of climate conditions on women’s attitudes towards wife beating. The demographic health surveys (DHS) dataset includes over 550,000 women in 38 countries, asked a series of wife beating justification questions in the domestic violence module. Using a linear probability model, we find prior year growing degree days (GDD), prior and current year rainfall variability have statistically significant effects. Most interestingly, we find that a one standard deviation (SD) rise in prior year annual rainfall decreases the likelihood of justifying …

Does Infant Formula Availability Reduce Breastfeeding?, Ingvild Madsen Lampe

Master's Theses

Abstract: Several key studies highlight the importance of breastfeeding and there is a broad consensus that it plays a crucial role for a child's health and cognitive development. This is especially true for the poor in developing countries, where vulnerable infants' access to proper nutrition is vital. We investigate the effect of introducing infant formula into a market on changes in breastfeeding patterns. Using the Demographic Health Surveys and annual reports from the baby food industry between 1981 and 2002 in 11 tropical countries, we find evidence that import of infant formula significantly reduces breastfeeding duration. The effects are stronger …

Use Of The Heat Stress Score To Predict Preparedness To Run In An Outdoor, Warm Weather Race, Rachel K. Katch

Master's Theses

No abstract provided.

Internalized Stigma Among Hiv-Positive Men On Antiretroviral Therapy In Urban India, Mitchell L. Irving

Master's Theses

No abstract provided.

Physical Activity: Lack Of Mitigation Of Adverse Effect Of Pro-Inflammatory Diet, Aivi T. Doan

Master's Theses

BACKGROUND: To date, no studies have evaluated if moderate and/or vigorous PA physical activity (mv-PA) mitigates the adverse effect of a pro-inflammatory diet. METHODS: We conducted a cross-sectional analysis using data from the National Health and Nutrition Examination Survey (NHANES) and constructed the Dietary Inflammatory Index (DII) score. Expenditure of mv-PA was obtained from two sources. Multivariate Logistic Regression was performed to calculate Odds Ratios (OR) and 95% Confidence Intervals (CIs). RESULTS: Participants with a DII score in the top quartile were 33% more likely to exhibit elevated CRP than persons with a DII score in the lowest quartile (referent). …

A Retrospective Study Assessing The Predictive Performance Of A Lung Cancer Screening Risk Prediction Model In A Clinical Lung Cancer Screening Program, Andrea K. Borondy Kitts

Master's Theses

Background: United States Preventive Services Task Force (USPSTF) and Centers for Medicare & Medicaid Services (CMS) recommendations for annual screening for lung cancer with low dose CT (LDCT) scans rely on age and smoking history to identify those at high risk for lung cancer. The Tammemagi et al. six year lung cancer risk prediction model, PLCOm2012, developed and validated in large lung cancer screening clinical trials, demonstrated good predictive performance in screening selection. However, the model has not been validated in clinical practice. Validating the model in clinical practice would increase confidence in its ability to provide information for shared …

Long-Term Feeding Ecology Of Early-Stage Striped Bass (Morone Saxatilis) And American Shad (Alosa Sapidissima) In The Hudson River Estuary, Michael G. Smircich

Master's Theses

No abstract provided.

Does The Shortened Environmental Symptoms Questionnaire Accurately Represent Physiological Adaptations Following A 10 Day Heat Acclimation Protocol And The Decay Thereafter?, Rachel Marie Vanscoy

Master's Theses

No abstract provided.

Increasing Sleep Duration In Collegiate Athletes: A Behavioral Intervention Involving Sleep Education, Self-Tracking, Goal Setting, And Self-Reinforcement, Leslie Greer

Master's Theses

The purpose of this study was to examine the impact of a behavioral intervention on sleep duration in a group of Division I student athletes from a women's rowing team. This participant pool was specifically selected because they have early morning practice due to several scheduling constraints, which can make adequate sleep duration more difficult to obtain. Further, the participants in this pool were selected because they had the lowest previous nights sleep and perceived average sleep duration, and therefore in most need of this type of intervention. A multiple baseline design was used to determine if a functional relationship …

Changes In Power And Movement Strategy Over One Athletic Season, Alison C. O'Connor

Master's Theses

Context: Female collegiate soccer athletes sustain injuries at a concerning rate, often with severe short and long-term consequences. Identifying changes in movement control and power that inherently occur over an athletic season may improve our ability to predict and ultimately prevent injury. Objective: The purpose of this study was to evaluate movement control and power over the course of an athletic season in female collegiate soccer athletes. Design: Repeated measures Setting: Field Study Participants: 25 female athletes (age: 20±1years, mass: 66.5 ±6.6kg, height: 1.7±0.1m) Intervention(s): None Main Outcome Measure(s): Participants performed jump-landing and vertical jump (VJ) tasks …

Technological And Managerial Gaps In The Adoption Of Improved Groundnut Seed Varieties In Uganda, Neha Paliwal

Master's Theses

The international community has successfully developed improved varieties of seeds that yield high returns in the presence of drought, pests, and disease. This effort is in response to the persistent concern of food security, especially in regions that are most vulnerable to climate change. This study uses cross-sectional data from the World Bank Living Standards Measurement Survey to obtain estimates for the adoption of improved groundnut varieties (IGVs) in Uganda as well as gaps in farmer managerial capacity (alternatively known as technical inefficiency). To do so, this study employs an adoption logit model, in conjunction with a stochastic production frontier …