Digital Commons Network^™

Functional Studies Of Novel Mosquito Stage-Specific Genes In The Malaria Parasite, Plasmodium Berghei., Kaitlyn Kiernan

Master's Theses

The development and survival of the malaria parasite Plasmodium within its mosquito vector is not very well understood. When the parasite is taken up by an Anopheles mosquito, it is exposed to digestive enzymes, reactive oxygen species, increasing pH, decreasing temperature, and a diverse microbial flora. Our lab is studying the adaptive mechanisms underlying parasite survival in this hostile environment, one of which is movement out of the midgut. In order to escape the midgut, the parasite develops into an elongated, motile form called the ookinete. I am investigating two genes, thioredoxin-like protein 1 (trxl-1) and subpellicular microtubule protein 1 …

Dexamethasone Treatment Effects On H3k27me3 Chromatin Organization Is Related To Nk Cell Immune Dysregulation, Michael Sarafeno Misale

Master's Theses

It is well-established that psychological stress reduces natural killer (NK) cell immune function. This reduction is mediated by stress-induced release of glucocorticoids (GC), which can suppress immune function. Associated with suppression of a particular immune function are GC induced histone-epigenetic marks. Histone-epigenetic marks are responsible for the organization and compartmentalization of genomes into transcriptionally active euchromatin domains that are localized to the interior of the nucleus. Transcriptionally silent heterochromatic domains are enriched with methylated epigenetic marks and are localized to the nuclear periphery. The purpose of this investigation was to assess the influence of GC on H3K27me3 chromatin organization by …

Developing Integral Ecologists: Description And Analysis Of The State Of Environmental Education At Jesuit High Schools In Light Of Religious Ecological Commitments And Science Education Research, Philip Nahlik Nahlik

Master's Theses

This research responds to numerous calls to focus more immediately and deeply on environmental education in the context of local communities. Jesuit high schools offer a rich network to study this movement, as schools with long histories of scholarly and moral concerns for forming students to think about and act on worldwide problems. The key research question is: How can science education research inform environmental education in these schools? The research methodology includes data collection and analysis of publicly-accessible website data, phone interviews with teachers, and a literature review of science education research. Recommendations are given for vertically aligning the …

Filling Pews, Speaking Truth: Pro-Life Ministry In A Liberal Catholic Parish, Jonathan Neidorf

Master's Theses

Scholars of the pro-life movement in the United States have extensively documented how pro-lifers in this country feel that their cause is embattled by society (Williams and Blackburn 1996; Maxwell 2002; Munson 2008). Other research argues that conservative Catholics tend to feel that their Church is swept up in an increasing liberalization in greater society, which serves to compromise core moral tenets of the faith (Leege 1988; Weaver and Appleby 1995; Wedam 1993). No thorough research exists examining how pro-life Catholics see their Church's and their parish's liberalism as directly suppressing their pro-life work. In this ethnographic study of a …

Multifunctional Regulatory T Cells From Human Umbilical Cord Blood And The Role Of Tumor Necrosis Factor In Immune Homeostasis, Alexander Nelson

Master's Theses

Regulatory T cells (Tregs) are required to suppress inflammation and prevent autoimmunity. During fetal development Tregs are crucial to maintain tolerance between mother and child. After birth, neonates require tolerance to avoid harmful immune responses to foreign antigens in food and allow colonization with commensal microbes. We demonstrate a propensity for T cells in human umbilical cord blood to differentiate into Tregs in response to antigen receptor stimulation ex vivo. Cord blood-derived Tregs potently suppress T cell proliferation, but also produce pro-inflammatory cytokines known to activate innate immune responses. These results suggest that antigen exposure during early life results in …

Domestic Violence Among Asian Indian Immigrant Women In The United States, Teuta Peja

Master's Theses

This study looks at how domestic violence is conceptualized by the research studies on

Asian Indian immigrant communities in the United States through different periods of time, and

how sociocultural factors are associated with domestic violence. Using the meta-synthesis

descriptive method, I analyzed and interpreted the findings of four research studies conducted

between 1995-2016 that included in-depth interviews with Asian Indian immigrant women who

experienced domestic violence. The analysis focuses on changes of the patterns of abuse, helping behavior, and leaving the abusive marriage as an option. The changes in U.S. domestic

violence legislation and policy regarding immigration and domestic …

Children's Exposure To Violence Across Contexts: Profiles Of Family, School, And Community Witnessing And Victimization, Catherine Mary Rice

Master's Theses

Children residing in low-income, urban neighborhoods are at a disproportionately higher risk of exposure to violence (ETV) across multiple contexts compared to their peers, including witnessing violence and direct victimization. The many negative effects of ETV are compounded when youth experience ETV across multiple settings and when these experiences are chronic. Despite this, much of the research on ETV during childhood focuses on a single form of violence (e.g., family victimization or witnessing community violence). The current study examines patterns of frequency of ETV, including witnessing and victimization, across family, school, and community contexts, using person-centered methods to elucidate the …

Characterization Of Inhibitory Molecules Produced By Lactobacillus Crispatus, Giuseppe Anthony Pistone

Master's Theses

Lactobacillus species are widely accepted as beneficial bacteria of the human microbiota1-8. Lactobacilli spp. are well documented to inhibit pathogens by production and secretion of hydrogen peroxide (H2O2), organic acids, and/or proteinaceous bacteriocins into their environment. Most research attributes bactericidal activity of cell free supernatant (CFS) to H2O2 and/or lactic acid. Here, I demonstrate that CFS from a clinical isolate of Lactobacillus crispatus contains a molecule(s) that inhibits uropathogenic Escherichia coli (UPEC) colony formation independently of H2O2 and organic acids. Physiologic concentrations of H2O2 and organic acids produced by L. crispatus do not inhibit UPEC colony formation. Incubation of UPEC …

Intersectional Stereotypes Of Race, Gender, And Facial Structure And Evaluative Judgments Of Leadership Ability And Workplace Fit, Avery Nichole Waklatsi

Master's Theses

Though the labor market is highly competitive and diverse, minority groups only hold 26.7%, of board positions, in companies on the Fortune 500 list (Alliance for Board Diversity Census, 2013). When tasked with hiring managers whom are presented with equivalent job qualifications, evaluators may rely on their subjective impressions in making an employment decision. The evaluator's subjective impressions may be informed by stereotypes of the groups to which applicants belong. The current study tests how stereotypes pertaining to race, gender, and facial structure inform evaluator judgments of managerial applicants' leadership ability and workplace fit. Leadership ability and workplace fit are …

Green Vs. White: An Examination Of Of Media Portrayals Of Radical Environmentalists And White Supremacists, Laurence Pedroni

Master's Theses

The rise of the Trump presidency has highlighted not only the white supremacist history of the U.S., but also reflects danger to the survival of the species in the form of wholesale climate change denial. These ideologies are not unique to Trump or his cabinet, instead reflecting long standing U.S. policy. This research seeks to examine how the U.S. media supports and propagates propaganda to support these hegemonic goals. Relevant literature and research seem to suggest that because radical environmental movements often challenge the hegemony of capital accumulation, they might be portrayed as more violent and a greater terrorist threat …

Construction Of Bacterial Strains Containing A Plasmid Producing An Opossum-Based Anti-Venom Peptide For Low Cost Production Of The Peptide, Angela Cifelli

Master's Theses

A cost-effective therapy for snake bites and other biological toxins could save thousands of lives each year. A low-cost therapy can be achieved using a bacterial host that expresses a peptide that prevents death when administered after exposure to these toxins. A protein expressed in opossums, lethal toxin neutralizing factor (LTNF), provides the animal’s resistance to venom and a variety of other toxins. A small peptide fragment of this protein provides the same lifesaving properties as the full protein sequence. A synthetic copy of this peptide was tested in mice exposed to rattlesnake venom and showed lifesaving potential. The peptide …

Unified Software Engineering Reuse: A Methodology For Effective Software Reuse, Charles Allen Flood

Master's Theses

Software is a necessity in the modern world, and that need is continuously growing. As expensive as the creation of all this new software is, the maintenance costs are even greater. One solution to this problem is software reuse, whereby already written software can be applied to new problems after some modification, thus reducing the overall input of new code. The goal in traditional software reuse is to produce a piece of software with enough flexibility to be used at least twice. Unfortunately, there are many difficulties in achieving software reuse using modern programming techniques. Even software built specifically for …

Isolated Incidents: A Short Story Collection, Justin Bryant

Master's Theses

In my collection titled Isolated Incidents: A Short Story Collection, I explore the themes of isolation and loneliness while using dark humor and a satirical voice as an undercurrent to move the narratives. Isolation and loneliness intrigue me, because they are triggered and motivated by contradictory emotions inside of us. Fear, love, hate, and even nonchalant attitude and happiness can all mix to make us feel isolated even when we are not alone. People can be isolated when surrounded by others at a dinner table, or in a crowed bar, or even a small office filled with co-workers. Loneliness is …

Crafting Autonomy: A Reevaluation Of The Pedestal In The Sculpture Of Arlene Shechet, Nicole Cherubini, And Francesca Dimattio, Sara Morris Morris

Master's Theses

New York-based contemporary artists Arlene Shechet, Nicole Cherubini, and Francesca DiMattio have each developed a sculptural style that integrates the pedestal within their sculptures. Primarily made from clay, unconventional craft materials, and commonplace objects, these sculptures formally and conceptually blur the lines between craft and fine art, décor and sculpture, as well as private and institutional space. With a renewed interest in craft and feminism, these artists test the material hierarchies that have historically determined the categorization of art inside institutional spaces. This study investigates how these sculptures gain autonomy when exhibited inside museums in light of contemporary theories on …

A 3d Framework For Characterizing Microstructure Evolution Of Li-Ion Batteries, Jeffrey David Gelb

Master's Theses

Lithium-ion batteries are commonly found in many modern consumer devices, ranging from portable computers and mobile phones to hybrid- and fully-electric vehicles. While improving efficiencies and increasing reliabilities are of critical importance for increasing market adoption of the technology, research on these topics is, to date, largely restricted to empirical observations and computational simulations. In the present study, it is proposed to use the modern technique of X-ray microscopy to characterize a sample of commercial 18650 cylindrical Li-ion batteries in both their pristine and aged states. By coupling this approach with 3D and 4D data analysis techniques, the present study …

Using Recycled Water For Potable Reuse In Santa Clara County, Ca: High School Students' Knowledge And Acceptance, Nicholas Ronald Ajluni

Master's Theses

The drought-prone State of California has an ever increasing demand for water. Potable reuse provides a viable alternative water supply, but public attitudes, knowledge, and acceptance have limited implementation. This study investigated the knowledge and acceptance that high school students have towards potable reuse. Previous research has identified four critical factors that influence acceptance of potable reuse: 1) knowledge of the wastewater treatment process, 2) knowledge of local water supplies, 3) trust in local water resource managers, and 4) belief in the need for a new water supply. This study uses both quantitative and qualitative methods through a Likert-style survey …

An Analysis Of The Attitudes Of Undergraduate Theology Majors Towards Members Of The Lesbian, Gay, Bisexual, And Transgender Community, Jephet Williams

Master's Theses

Problem and Purpose

Research has identified students’ attitudes towards the lesbian, gay, bisexual, and transgender community as being determined partly by the students’ understanding of gender identity, and partly by a further mixture of variables that include religiosity, gender, and ethnicity. Most of this previous research has been undertaken in either secular or non-Adventist settings. This present study examines attitudes of undergraduate theology majors at two Adventist universities in North America and the Caribbean.

Method

A Likert Scale was constructed consisting of eight questions geared to elicit attitudes across a number of areas. Sixty-three students completed the questionnaire. Participating students …

Evaluating Contradicting And Confirming Evidence: A Study On Beliefs And Motivated Reasoning, Zachary Alan Caddick

Master's Theses

The purpose of this study is to examine ideological, psychological, and demographic predictors of motivated reasoning. Three-hundred and seventy-seven participants from Amazon’s Mechanical Turk system completed written responses critically evaluating strengths and weaknesses in a vignette on the topic of anthropogenic climate change. The vignette has two fictional scientists present prototypical arguments for and against anthropogenic climate change that are constructed with equally flawed and conflicting reasoning from both view points. Written responses were coded by a team of trained and reliability assessed qualitative raters. Motivated reasoning is operationalized by providing supporting evidence for the congruent belief and counter evidence …

Variation In Organismic Rna And Dna Content: Analysis And Application To The Assessment Of Living Planktonic Biomass, Elizabeth Lam Gagneron

Master's Theses

Modern analysis of DNA and RNA nucleic acid sequences has yielded profound changes in our understanding of the genetic biodiversity of planktonic organisms within the microbial food web of aquatic ecosystems. However, the bulk environmental concentrations of DNA and RNA, and their relative ratios, also potentially provide important information on the biomass and metabolic activity of planktonic organisms. Currently, there is a need to quantify the relative living biomass levels of natural water contained in ships’ ballast tanks to regulate the spread of aquatic invasive species (AIS) resulting from ballast water discharge practices within the international shipping industry. Ultraviolet (UV) …

Mémoires: The Revolutionary Map Of The Twentieth Century, Megan Merritt

Master's Theses

The artistic collaborations between Guy Debord and Asger Jorn blossomed in 1957, and have typically been explored in terms of their context within the canon of the Situationist International (SI), a notorious group of political thinkers and activists who formed in July, 1957, with a shared repulsion for capitalism and consumerism. Before co-founding the SI with Jorn and several other individuals, Debord was part of the Lettrist International, a splinter group of the Lettrists, which allowed Debord more authority and autonomy to create his first film, Hurlements en Faveur de Sade (Howls for Sade, 1954), and explore other media that …

Historical Trauma And Refugee Reception: Armenians And Syrian-Armenian Co-Ethnics, Nicole M. Campos

Master's Theses

This thesis considers the ways in which Armenian history has influenced integration of Syrian-Armenian refugees into Armenia due to the ongoing Syrian War. Ethnic Armenian outlooks were analyzed relative to the influx of Syrian refugees, particularly co-ethnic Syrian-Armenians. Field work in Armenia found a sustained cultural impression of Armenians’ Soviet membership and genocide. Findings suggest that recognizing the importance of history as it may or may not affect migration reception policies and attitudes is important to developing sustainable resettlement environments, at least until repatriation or third-country resettlement becomes an option to migrants. Ultimately, this thesis argues that more attention must …

Defining “Justice” In Post-Conflict Societies By Exploring The Case Of The Armenian Genocide., Narek Ghazaryan

Master's Theses

This study examines the many different approaches towards justice in post-conflict societies. It analysis the two main theories of justice and uses the Armenian Genocide as a case study to comprehend what constitutes justice in the aftermath of a humanitarian crisis. This study aims to define “justice” by the Armenian population in forms of surveys and expert interviews. It is the community who is directly impacted by the crisis can indeed identify what justice mean to them. For a society to heal in the aftermath of conflict justice needs to be served in order to restore peace and harmony. For …

Loss Of Identity, Radicalization, And Terrorism, Magdalena Martinez

Master's Theses

France and Belgium are two of the top countries in Europe with an increasing number of root fighters. Over the last two years, both countries have been primary targets of terrorism. This thesis investigates the repeated pattern of events and analyzes from a birds-eye view the cycle leading to the rise of terrorism in France and Belgium. This research disputes that anxiety causes discrimination and lack of integration in France and Belgium, which contributes an identity crisis. In essence, these factors trigger radicalization and lead to terrorism. Analyzing the patterns of terrorist activity and the path of radicalization is essential …

The Electoral Success Of Communist-Successor Parties In The Czech Republic And Romania, Harley L. Roe

Master's Theses

Communist-successor parties are impacted by six social and political factors: party reimaging, coalition building, corruption and scandal, party leadership, EU accession, and social indicators. This project explores how the descendants of the totalitarian communist parties in the Czech Republic and Romania are influenced by each factor by analyzing election result data against these indicators. Party reimaging and coalition building are the most influential in determining voter turnout, while the other four work in conjunction to influence election results. This project contributes to the literature on electoral volatility, post-communist countries, voter behavior, and seeks to offer a model that can predict …

Notions Of Discontent And Distinction: Reflections Of Young Diasporic Taiwanese Americans, Andrew T. Chen

Master's Theses

In 1971, Taiwan lost its seat in the United Nations and has been vying for international validation ever since. The Kuomintang’s (KMT) loss and the development of Taiwan’s democracy has left millions with varying opinions pertaining to the status of Taiwan. It also brings up the importance of what it means to be Taiwanese and how Taiwanese people identify and distinguish themselves from China. For much of the Republic of China’s (ROC) existence in Taiwan the independence movement for the de facto nation-state has lived outside of its borders, making achievements and enduring hardships for Taiwan and Taiwanese Americans throughout …

Islamophobia In The United States How American News Coverage And Social Media Perpetuate Fear & Hate Against Islam, Rida Kazmi

Master's Theses

In recent years, Islamophobia in the United States has risen to levels never seen before. While 2016 marks the 15-year anniversary of the 9/11 attacks, hatred and fear of Muslims and Islam has reached an all-time high instead of steadily decreasing. The rise in Islamophobia is due in large part to the news coverage that people are exposed to, with media stories on terrorist attacks often conflating Islam and violence in both subtle and other ways. Furthermore, we see that similar coverage of acts of violence committed by non-Muslims is often markedly different, both in tone and language. Through American …

Challenging Filipino Colonial Mentality With Philippine Art, Francesca V. Mateo

Master's Theses

For 350 years, the Philippines was colonized by Spain and the United States. The Philippines became a sovereign nation in 1946 yet, fifty years later, colonial teachings continue to oppress Filipinos due to their colonial mentality (CM.) CM is an internalized oppression among Filipinos in which they experience an automatic preference for anything Western—European or U.S. American—and rejection of anything Filipino. Although Filipinos show signs of a CM, there are Filipinos who are challenging CM by engaging in Philippine art. Philippine art is defined as Filipino-made visual art, literature, music, and dance intended to promote Philippine culture. This …

The Politics Of Contagion, Joseph M. Young

Master's Theses

Contagion events have occurred throughout history leaving death and destruction in their wake. Often sensationalized in movies and shows such as Contagion and The Walking Dead, contagion events are life-altering events filled with gory symptoms and elevated mortality rates. The dangers of contagion events prompted governments to develop agencies with the purpose of preventing and mitigating the risks contagions pose. The Centers for Disease Control and Prevention (CDC) and other agencies across the globe pour millions of dollars each year into eliminating the risk of contagions and making the world a safer place. However, while more resources are dedicated to …

"Who Am I?": The Development Of A Male Palestinian Political Identity, Tala J. Dayyat

Master's Theses

The Palestinian people have lived under numerous imperial rulers; first, the Ottoman Empire, then later the British. Today they live under the military occupation of the state of Israel as second class citizen millions more living abroad as refugees. Young Palestinian men have become the leaders and the physical manifestation of the struggle against Israel, a political Goliath that has used tactics to repress the Palestinians such as, detentions, beatings, and land confiscation, which many outside of the Israeli state deem as illegal. Scholar Rashid Khalidi states that “the quintessential Palestinian experience, which illustrates some of the most basic issues …

Distorting The Life Of Maca (Lepidium Miyenii), Fabiola Tavui

Master's Theses

The supply and demand of maca (Lepidium Miyenii), a native Peruvian vegetable, increased over the past decade; however, it has recently reduced. There are many implications for this outcome. Maca, a product with several health benefits, caught the attention of not just foreign businesses and investors but also of Peruvians. As maca became highly commercialized and exported abroad, the actors involved in the maca “business” at all levels contributed to its market to prospered but also to crumble. Some of the reasons due to the exploitation of maca itself for economic gains; distorting maca’s ecological environment and relation …