Digital Commons Network^™

Family Matters: Experiences Of Family Stigma, Addiction Recovery & The Role Of Self-Compassion, Kennedy Hoying

Master's Theses

Addiction and substance use is currently one of the most stigmatized disorders in society, creating a barrier to treatment and recovery. This study explored the role of family stigma, the stigmatization processes of family members of otherwise stigmatized individuals, within families of substance users to examine how stigma might affect family support behaviors. Two hundred and twenty-two U.S. adults who have a substance using family member completed an online survey regarding their experiences of family stigma, attributions of responsibility for addiction, self-compassion, and any supportive recovery behaviors they engage in to help their family member’s addiction. Results of correlation analysis …

Anthropogenic Litter In Freshwater Ecosystems: Effect On Ecosystem Processes And Spatial Distribution, Emily Johnson

Master's Theses

The rapid increase of plastic production and disposal into the environment has resulted in anthropogenic litter (i.e., trash; AL) becoming a global problem. In aquatic ecosystems, macro- and microplastics are long-lived, mobile, and interact with the physical and chemical components of aquatic ecosystems. Our objectives were to: (1) assess the impact of microplastic pollution on the ecosystem processes of ecosystem metabolism and N2 flux in an oligotrophic lake and (2) to assess the abundance and assemblage of anthropogenic litter in a large urban river. For objective (1), we added microplastics at a range of concentrations to littoral mesocosms. Ecosystem metabolism …

Returning To Simplicity In Early Daoist And Ancient Greek Thought, Abdulaziz Abdulrahman Alfailakawi

Master's Theses

Underlying both the voluntary simplicity and minimalist lifestyle movements is the sentiment that living a simple life leads to tranquility. Despite purported instances where tranquility is experienced through simple living (Hitz, 2020), one can identify instances where, despite living simply, one does not experience tranquility. If living simply is not sufficient for tranquility, what is? In this project I argue that “simplicity” is the inner condition necessary and sufficient to experiencing tranquility. While some argue that simplicity is a practical virtue (Compte-Sponville, 2001; Gambrel and Cafaro, 2010; and Martin, 2012), I argue that simplicity, what is linguistically defined as the …

The Mechanisms Of Heterogenic Necrotic And Apoptotic Cell Death Fates In Human Epidermal Keratinocytes Following Uvb Exposure, Madeline Zoe Tara

Master's Theses

UVB radiation is a carcinogen that triggers inflammation and contributes to skin carcinogenesis. Although UVB exposure can induce apoptosis, this form of cell death is non-inflammatory and thus cannot explain the inflammatory response observed following UVB. Necrotic regulated cell death (RCD) pathways, namely necroptosis, pyroptosis, and PANoptosis, are inherently pro-inflammatory, and thus this study focused on characterizing these in irradiated human epidermal keratinocytes. Keratinocytes were irradiated, treated with cell death inhibitors, and analyzed for apoptotic and necrotic RCD markers using immunofluorescence (IF). Despite uniform UVB exposure, keratinocytes displayed heterogeneous cell death responses, and these findings were validated in ex vivo …

Novel Electrospinning Techniques For Fabricating Scaffolds To Model Intracranial Atherosclerotic Disease In Tissue Engineered Blood Vessel Mimics, Isaac "Squeaky" Buentipo

Master's Theses

Novel Electrospinning Techniques for Fabricating Scaffolds to Model Intracranial

Atherosclerotic Disease in Tissue Engineered Blood Vessel Mimics

Isaac “Squeaky” Buentipo

Dr. Kristen Cardinal’s Tissue Engineering Lab at California Polytechnic State University specializes in fabricating customized vascular models, known as Blood Vessel Mimics (BVMs), for medical device testing. BVMs are simplified in vitro vascular models designed to bridge the gap between bench testing and in vivo evaluation of intravascular medical devices. BVMs are produced by combining a polymer scaffold with human vascular cells. Through novel scaffold fabrication techniques, such as silicone injection molding, silicone dip casting and electrospinning, the capabilities of …

Evaluation Of Antibiotic Testing Protocols For Biofilm-Forming Escherichia Coli In A Microfluidic Platform, Caleb R. Telander

Master's Theses

Catheter-associated urinary tract infections remain an ongoing clinical problem due to biofilm persistence and antibiotic resistance. Standard antibiotic susceptibility testing cannot accurately reproduce flow conditions and the spatial complexity of the in vivoenvironment and is thus questionable in relevance to device-related infections. This study examines a microfluidic device designed to simulate physiologically relevant wall shear stress and antibiotic gradients in Escherichia coli biofilms. The polydimethylsiloxane-based system integrates a 16-well culture chamber with a gradient generator. Biofilm growth was observed using fluorescence microscopy of green fluorescent protein-labeled bacteria. Simulations performed using COMSOL Multiphysics software estimated the appropriate range of wall …

Acoustic And Hemodynamic Analysis Of Phantoms: Roughness And Flow Dynamics, Ethan Erik Olof Sundberg

Master's Theses

The purpose of this study was to determine whether different vascular phantoms, with and without a surrogate arm, could serve as effective analogs to the human brachial artery for assessing endothelial dysfunction, an early indicator of cardiovascular disease, particularly atherosclerosis. Atherosclerosis is characterized by plaque buildup and endothelial damage, which precede more severe clinical events and are often detectable through changes in vascular function. A 40” water tower was used to simulate diastolic pressure, enabling water flow through each phantom. Strain gauge pressure transducers were placed at both ends of the phantoms to measure pressure drop, while a microphone captured …

A Manufacturing Process For Interdigitated Microelectrodes On Glass Wafers, Wyatt W. Warfield

Master's Theses

This study presents work done to optimize the process parameters to produce interdigitated electrodes on a borosilicate wafer. Using designed experiments and statistical analysis, the error in pattern transfer was minimized using for key process steps including exposure time, develop time and post exposure bake duration. Similarly, statistical analysis was used with profilometry data to fine tune the develop times. Qualitative analysis was used to assess thin film deposition. The resulting process produced wafers with improved pattern transfer and adequate film adhesion

Optimizing Microfluidic Murine Fibroblast And Human Epidermal Keratinocyte Cell Culture In 70Μm Microwells, Christian Navarro

Master's Theses

Cell culture is an essential technique utilized in biotechnology and medicine to remove systemic influences to study cellular behavior and morphological development of individual cell lines. However, conventional cell culture is two-dimensional and static meaning it can’t easily mimic in vivo conditions such as multicellular cell to cell interactions, fluid perfusion, or 3D structures which might alter cellular behavior and morphology. Microfluidic cell culture allows for the incorporation of in vivo conditions such as perfusion and chemical gradients allowing for more physiologically accurate models. The goal of this study is to develop a protocol for testing a microfluidic chip designed …

Studies On The Effects Of Cap Management On The Oxidation–Reduction Potential, Phenolic Composition, And Sensory Properties Of Red Wines, Dallas J. Parnigoni

Master's Theses

Cap management during alcoholic fermentation of red wines plays a critical role in modulating the phenolic and volatile extraction from grape solids, influencing the homogenization of chemical and temperature gradients, while imparting oxygen to the must. Different cap management alternatives are also thought to influence the evolution of the oxidation-reduction potential (ORP). It is critical to understand how different cap management protocols affect these variables to design a cap management protocol tailored to wine style and varietal. This thesis investigated the effects common commercially applied cap management protocols, as well as the efficacy of novel, automated gas mixing protocols as …

"Great Big Beautiful Tomorrow": Disneyland, Science, And The Cultural Cold War, Emily Searson

Master's Theses

Disneyland, the popular Anaheim-based theme park in California, opened its doors during heightened Cold War tensions in 1955. In this thesis, I trace the origins of Tomorrowland, one of the five original themed lands in Disneyland that included futuristic rides and attractions to depict Walt Disney’s imagining of the year 1986. I examine Tomorrowland in particular to argue that WED Enterprises (Disneyland, Inc.’s research and development arm) and Disney’s vision of scientific progress aligned with U.S. Cold War policy goals, especially containment. Disney and WED Enterprises meticulously planned Tomorrowland with the help of notable American defense contractors, including the Monsanto …

Bandwagon Behavior In Major League Baseball, Daniel E. Erro

Master's Theses

This study investigates “bandwagon” behavior among Major League Baseball (MLB) fans by analyzing Google search interest data from 2004 to 2019. Drawing on publicly available information from Google Trends, the analysis explores how fluctuations in search activity align with team performance during both the regular season and postseason. Hierarchical linear models are used to estimate expected levels of fan interest based on team performance and market characteristics. Deviations from these expectations during the regular season are interpreted as evidence of bandwagon or anti-bandwagon behavior. A drop-off in interest following playoff elimination is also examined to capture shifts in fan attention …

Functionalization Of A Calcium-Based Squaric Acid Metal Organic Frameworks With Amine-Based Polymers For Enhancing Post Combustion Carbon Capture, Corinne D. Watson

Master's Theses

The primary driver of climate change is the release of carbon dioxide (CO₂) from fossil fuel combustion. Global climate change has resulted in sea level rise, adverse weather patterns, and countless other negative global effects. Several carbon-reduction frameworks emphasize the transition to clean energy sources; however, other strategies must be concurrently pursued to immediately and effectively reduce atmospheric carbon dioxide point source emissions. Metal organic frameworks (MOFs) are a promising new technology for post-combustion carbon dioxide capture. The materials are synthesized using organic linker molecules and metal ion joints. Notably, there are several challenges with various types of …

Investigating Social Presence In Collaborative Keys For Asynchronous Courses, Lily P. Cook

Master's Theses

Asynchronous virtual courses have become increasingly popular in the years following the global Covid-19 pandemic. These courses, with no set meeting schedule, offer flexibility to both students and instructors, but pose challenges for developing a collaborative learning environment. The Community of Inquiry framework (Rourke et al., 1999) identifies three essential components in an online course necessary to foster a collaborative environment- teaching presence, cognitive presence, and social presence. Social presence is especially impacted in asynchronous learning settings, which presents challenges for the students to display their personalities and connect with the community. This study investigates Collaborative Keys (CKs), structured collaborative …

Flair: A Fog-Native Workload Placement Framework For Qos-Aware Scheduling In Smart Manufacturing, Daiwik N. Swaminathan

Master's Theses

Smart manufacturing environments utilize a variety of heterogeneous IoT sensors that continuously stream large volumes of data. To detect and mitigate critical events such as fires or accidents in real time, this data must be promptly analyzed by machine learning (ML) image classifiers. These classifiers are typically deployed on fog computing nodes located within the manufacturing warehouse facilities to ensure low-latency responses and to protect data privacy. Although fog nodes offer a better alternative to remote cloud data centers for such latency-sensitive tasks, they are often resource-constrained and highly sensitive to the composition of workloads, particularly in heterogeneous environments where …

Data-Driven Product Recommendations: A Decision Support Framework Utilizing Customer Reviews, Tyler A. Lopez

Master's Theses

With the considerable presence of e-commerce in society, vast number of purchasable goods, and increasing brand variety, consumers are faced with the challenge of buying products that they perceive to be of greatest value to them. To assist consumers with making better informed decisions, e-commerce websites allow individuals to post their own experiences and score the products that they purchase. Despite this information, the variety of experiences and feedback that consumers share do not always lead to clarity on whether a product is best suited for the purchaser. To help guide customers through a simplified purchasing process from the perspective …

Vertical And Latitudinal Variability Of Marine Heatwaves In The California Current, Gavin M. Plume

Master's Theses

Marine heatwaves (MHWs) are increasing in frequency and intensity globally, with grave effects on marine ecosystems and their dependent industries. There are significant gaps in knowledge of the subsurface behavior and geographic distribution of MHWs, especially in eastern boundary upwelling systems like the California Current. Here, two decades of full water-column temperature observations from a shallow autonomous profiler in San Luis Obispo Bay (~10m) revealed that while MHWs have similar average durations and intensities across all depths, one-third of bottom MHWs occur without a concurrent surface signal. MHWs across the water column initiated during anomalously weak upwelling or downwelling conditions …

Clusters, Trends, And Choices: Feature Selection In Interactive Statistical Graphics, Dylan Le

Master's Theses

Exploratory data analysis (EDA) is a method for uncovering the structure and key characteristics of data, often through the use of statistical graphics. These visual tools can reveal patterns and trends, and their effectiveness can be enhanced through interactivity. By enabling users to filter data, zoom, and toggle visual features, interactive plots can accelerate and enrich the EDA process. This study extends a previous graphical study by incorporating an interactive framework. Using a statistical lineup protocol with two target patterns (a linear trend and a clustering trend) participants interacted with plots by toggling various aesthetic features, including cluster coloring, ellipses …

Correlations Between Social Media, Body Image Perceptions, And Disordered Eating Prevalence In Postpartum Women: A Pilot Cross-Sectional Study, Hannah Smith

Master's Theses

Postpartum women are a high-risk population for body dissatisfaction and disordered eating behavior due in part to the plethora of hormonal and physiological changes. Despite this, research examining this issue among postpartum women remains limited.

This pilot cross-sectional study investigated the relationship between social media use, body dissatisfaction, and disordered eating behavior among women up to 13 months postpartum. For this study, the following research questions were asked: Is high social media usage associated with higher levels of disordered eating among women up to 13 months postpartum? Is the association between social media usage and disordered eating mediated by a …

Subalpine And Alpine Plant Community Turnover In Yosemite National Park Following 30 Years Of Climate Warming, Rachel Friesen

Master's Theses

Subalpine and alpine regions in California are warming more rapidly than lower elevations. In response, high-elevation plants may acclimate or adapt to the new climate, move to higher elevations or latitudes, persist in refugia, or go extinct. While models predict substantial declines in subalpine and alpine plant communities due to discontinuous population distributions and lack of upslope area, actual responses may vary due to lags in dispersal, establishment, and extinction. Although shifts in high-elevation plant communities have been documented in other regions of the world, such changes have not yet been studied in Yosemite National Park. To assess high-elevation plant …

Assessment Of The Imx7ulp Heterogeneous Soc For Use In A Next Generation Student Cubesat Obc, Lorenzo A. Pedroza

Master's Theses

CubeSats represent a rapidly evolving platform for space research, industry, and education, demanding increasingly sophisticated onboard computing solutions that balance performance, fault tolerance, size, weight, and power constraints. Although the design of the Cal Poly's CubeSat Lab's (PolySat) current On-Board Computer (OBC) keeps up with many of these factors, the demands of modern workloads like fine attitude determination will start to outpace available compute. While the selection of a more capable processor to address this would have traditionally resulted in increased energy usage, modern system-on-chip (SoC) architectures offer novel ways to trade available compute for power savings on-the-fly. With this …

Thermal Modeling Techniques For Additively Manufactured Porous Metals, Lucas D. Rambo

Master's Theses

Advances in additive manufacturing have enabled the creation of metallic components with tailored porosity, offering design flexibility for thermal, structural, and fluid transport applications. This thesis investigates the effective thermal conductivity (ETC) of porous Inconel 625 (IN625) and Inconel-ceramic composites (IN625-RAM2) fabricated by Laser Powder Bed Fusion (LPBF) using Elementum 3D’s PermiAM technology. Experimental measurements of thermal conductivity using the laser flash method are compared to numerical models built from micro-computed tomography data. Simulations were performed using both finite element (FE) and finite volume (FV) methods to evaluate thermal transport in real microstructures. The study investigates the effects of micro- …

The Effect Of Dietary Strawberry Supplementation On Glycemic Control Factors In Overweight And Obese Postmenopausal Women With At-Risk Diabetes Mellitus Pathogenesis, Jennifer Herrera

Master's Theses

Glycemic control is directly related to type II diabetes mellitus (T2DM). As of 2023, 30.5 million Americans have T2DM, and this number only continues to increase exponentially across the world (“Facts & Figures,” n.d.). T2DM is only a precursor to fatal conditions including cardiovascular disease, the number one cause of death in the United States. Extensive research has revealed that strawberries, a high polyphenolic food, may pose positive effects on glycemic control biomarkers. This study aimed to investigate the effect of three servings of strawberries in the form of 39-g of freeze-dried strawberry powder (FDSP) for six weeks on glycemic …

Remote Monitoring And Control Of Protection Relays Via Programmable Logic Controller, Rio Mcgown-Kauffman

Master's Theses

The purpose of this study is to explore the ability of a programmable logic controller (PLC) to wirelessly monitor and control power protection relays. The technologies surrounding power protection and industrial automation are ever evolving and have developed significantly in recent history. Industrial power applications call for consistent condition monitoring and status updates for various high-importance components. The high-importance components have power protection schemes that are managed by digital relays to trip circuit breakers in fault or unsafe operating conditions. The smart relays have a wide range of capabilities, including communications. Cal Poly assembled a collection of relays from Schweitzer …

Bentonite Erosion And Cation Exchange Effects On Hydraulic Conductivity Of Geosynthetic Clay Liners, Grace Paananen

Master's Theses

Geosynthetic clay liners (GCLs) are used in municipal solid waste landfill (MSW) liner and cover systems as an alternative to thick compacted clay layers. Previous field studies have revealed potential for bentonite erosion in GCLs when subjected to wet-dry cycles that occur when GCLs are placed on slopes, covered with a geomembrane, and left exposed without additional soil cover. A laboratory test program was conducted to quantify the effects of bentonite erosion on hydraulic conductivity of sodium-bentonite geosynthetic clay liners and samples subjected to cation exchange treatment in addition to bentonite erosion. This test program determined what level of bentonite …

The Relationships Among Orthorexia Nervosa, Perfectionist Tendencies And Academic Achievement In Nutrition And Dietetics Students, Sophia Grace Owens

Master's Theses

Eating disorders can cause a disturbance in how the health of food is viewed (Cerniglia et al., 2017). If a person has disturbances in their eating behaviors that can cause harm to their health, but the behaviors do not fit into the criteria of a specific eating disorder, they fall into the category of a disordered eating pattern (Academy of Nutrition and Dietetics, 2018). Because of the stress the college environment can cause students, some college students may cling to anything they can control, which may be reflected in their dietary habits. Orthorexia Nervosa (ON), a disordered eating pattern, is …

The Impact Of Growth Hormone-Releasing Hormone Antagonist On Human Adipose-Derived Stem Cells, Jeanne Michelle Dugas

Master's Theses

Obesity is a condition that affects over 40% of American adults and contributes to numerous preventable health issues. This condition is caused by increased adipose tissue, which forms when stem cells transform into adipocytes. Mesenchymal stem cells, including human adipose-derived stem cells (hASC), are multipotent with the ability to differentiate into adipocytes, osteocytes, or chondrocytes. Many factors affect this transformation, including the peptide growth hormone-releasing hormone (GHRH). The main role of GHRH is to trigger the release of growth hormone, but it has also been found to play an important role in adipocyte metabolism. We expect that if the differentiation …

The Antioxidant Potential Of Rosemary Leaf-Derived Nanovesicles, Shani Akila Griffin

Master's Theses

Human dermal fibroblasts are essential for maintaining skin homeostasis. However, exposure to exogenous and endogenous stressors can lead to fibroblast instability, extracellular matrix degradation, and excessive reactive oxygen species (ROS) production. These factors contribute to skin aging and ROS-induced skin disorders leading to hair loss. Adverse effects from synthetic treatments have driven interest in natural alternatives like plant extracts for skin therapy. However, the polyphenols in these treatments require an effective delivery system to ensure their stability and targeted application. Plant derived nanovesicles (PDNVs) are emerging as a promising natural alternative for therapeutic applications. Their biocompatibility, stability, and encapsulated compounds …

Dsa-Api: Data Standardization Automation Using Ai-Powered Apis, Andrew Asher Turner

Master's Theses

The common factor with current implementations of Artificial Intelligence (AI) is data. Companies are constantly looking for new ways to analyze data, but it comes in various formats: Text, Comma Separated Value (CVE), JavaScript Object Notation (JSON), Extensible Markup Language (XML), and Excel. How can AI be adapted to standardize formats for data analysis, integration, and digestion efficiently? Published research acknowledged that Machine Learning (ML) and AI can provide an automated method to speed up this process and limit the human decision-making error. With the advancement in AI, Application Programming Interfaces (APIs) prompt the idea that they can take in …

Breaking Barriers: How Reusable Menstrual Products Can Enhance School Attendance And Education For Girls In Kenya, Talia Jacobson

Master's Theses

In Kenya, statistics show that at least one in ten girls who are of the age of puberty miss school during their menstruation hindering their ability to finish schooling, secure a stable employment, and live independently. This thesis aims to highlight the issue of girls missing school due to their menstrual cycle, a problem that persists globally despite being solvable. The primary focus is on how reusable sanitary products, such as reusable pads, can aid girls to stay in school longer by addressing affordability and accessibility issues associated with commercial products, while also offering environmental benefits. The question guiding my …