Desert Hedgehog Is A Mammal-Specific Gene Expressed During Testicular And Ovarian Development In A Marsupial, William A. O'Hara

Master's Theses

Desert hedgehog (DHH) belongs to the hedgehog gene family that act as secreted intercellular signal transducers. DHH is an essential morphogen for normal testicular development and function in both mice and humans but is not present in the avian lineage. Like other hedgehog proteins, DHH signals through the patched (PTCH) receptors 1 and 2. Here we examine the expression and protein distribution of DHH, PTCH1 and PTCH2 in the developing testes of a marsupial mammal (the tammar wallaby) to determine whether DHH signalling is a conserved factor in gonadal development in all therian mammals.

An Exploratory Investigation Into The Use Of Eaup As An Alternative To Text-Based Passwords, Joseph Ahor Abandoh-Sam

Master's Theses

Security is one of the major concerns of every industry in the world today. One of the best ways of hacking into a computer system is brute forcing. And with the increase in computing, brute forcing has become faster and easy to do. Text-based passwords are still the most popular and most commonly used form of authentication even though the requirements for a good password are still increasing. Research has shown that the best text-based passwords are the random ones that have no sequence or pattern to them. But this also makes it difficult to remember. Well- documented research has …

One Sex, One School, Who Wins: How Single-Sex Learning Environments Impact Educational Attainment, Socio-Emotional Health, And Ambitions, Bradley Kirshenbaum

Master's Theses

Research on single-sex schools has covered a variety of matters regarding the effectiveness of their programs. This paper examines research on single-sex schools over the past 30 years in an effort to harmonize the past discourse with present trends. Journal articles and government research were used to synthesize the variety of methods used to ascertain whether single-sex schools have a positive influence on boys, girls, or both parties. Research trends have overwhelmingly supported all-girls schools, while remaining skeptical of any positive influence on boys. Much of the research supporting all-girls schools also suggests that single-sex schools' benefits are applicable to …

Stirring Up The Fires : John Spencer Bassett, "The Negro Question" Ansd Southern History, Robert Spencer Dicks

Master's Theses

In 1903 John Spencer Bassett, a young history professor at Trinity College, took to his pen to produce, "Stirring up the Fires of Racial Antipathy," a bold article intended to provoke discussion about southern race relations. An intense public backlash followed, nearly costing Bassett his job . The event, known as the "Bassett Affair," made national headlines. Many scholars have referenced the "Bassett Affair" as a triumph for academic freedom or as a part of a larger story about southern dissent. The 1903 controversy, however, was just one episode in the story of this iconoclastic historian. Delving into Bassett's personal …

Mental Arithmetic Across Three Language Groups, Tianyu Luo

Master's Theses

Mental arithmetic performance was investigated among three language groups (English monolinguals, Chinese-English bilinguals, and Spanish-English bilinguals). Participants solved both small and large numerosity arithmetic problems in addition and multiplication and reported their solution strategies. All groups performed better in small problems than in large ones and better in addition than in multiplication, especially for a large size set. The results revealed all three groups performed equally well in solving problems correctly. Spanish-English bilinguals were equivalent to their English monolingual peers. However, Chinese-English bilinguals outperformed the other two groups in solution speed, especially when problems consisted of large numbers. No group …

Differential And Temporal Immunomodulation Of Alpha4 Integrins On Cd4+ Memory Cells By Bordetella Pertussis And Bordetella Parapertussis, Dipti Ravindra

Master's Theses

Pertussis, caused by Bordetella pertussis (B. pertussis), is reemerging worldwide due to vaccine inefficacy. The hallmarks of infection are extreme lymphocytosis and delayed recovery, which are partially associated with pertussis toxin. Lymphocytes migrate to infected tissues using trafficking receptors. Specific combinations of these lymphocyte trafficking receptors are identified for skin and gut but are not well established for lung.

This study focused on the effect of pertussis toxin on lung-associated trafficking receptors and tested the hypothesis that pertussis toxin alters dendritic cell imprinting of lung trafficking receptors on T cells, thus delaying resolution of the infection. B. pertussis-infected mice were …

Plasmablast Frequency And Trafficking Receptor Expression Are Altered In Pediatric Ulcerative Colitis, Nicole Jeanne Tarlton

Master's Theses

Background: The incidence of pediatric ulcerative colitis (UC), a chronic autoinflammatory disease of the colon, is on the rise. Although an increased infiltration of B cells from the peripheral blood into the colon occurs in UC, B cell trafficking is understudied. We hypothesized that the frequency of circulating plasmablasts (PBs) and their trafficking receptor (TR) expression may be indicative of the location and degree of pathology in pediatric UC. Methods: We conducted multicolor flow cytometry analyses of circulating IgA+/- PBs and IgA+ memory B cells (MBCs) in pediatric UC patients with remission, mild, moderate, and severe disease (n=12) and healthy …

Chi-Squared Distance And Metamorphic Virus Detection, Annie Hii Toderici

Master's Theses

Malware are programs that are designed with a malicious intent. Metamorphic malware change their internal structure each generation while still maintaining their original behavior. As metamorphic malware become more sophisticated, it is important to develop efficient and accurate detection techniques. Current commercial antivirus software generally try to scan for malware signatures within files and match them against a known set of signatures; therefore, they are not able to detect metamorphic malware that change their body from generation to generation, with each copy comprised of its own unique signature. Machine learning methods such as hidden Markov models (HMM) have shown promising …

Emission From O2 Gas In The Kleinman-Low Region Of The Great Nebula In Orion, Michael Denney Turner

Master's Theses

We calculated line intensities of ground-state emission from atomic ([O I]) and molecular (O₂) oxygen under various conditions of temperature (10–10⁴ K) and density (10–10⁴ cm^-3) in photodissociation regions (PDR) of molecular gas clouds, with UV flux intensity (G₀) of 10⁵. Using a magnetohydrodynamic shock model to produce profile data in a range of pre-shock velocities (5 ≤ v_s ≤ 20 km s^-1) and a range of pre-shock H and H₂ gas densities (10³–10⁵ cm^-3), we calculated line intensities for both …

Reproduction Of Twentieth Century Intradecadal To Multidecadal Surface Temperature Variability In Radiatively Forced Coupled Climate Models, Patrick Thomas Brown

Master's Theses

Coupled Model Intercomparison Project 3 simulations that included time varying radiative forcings were ranked according to their ability to consistently reproduce twentieth century intradecadal to multidecadal (IMD) surface temperature variability at the 5° by 5° spatial scale. IMD variability was identified using the running Mann Whitney Z method. Model rankings were given context by comparing the IMD variability in preindustrial control runs to observations and by contrasting the IMD variability among the ensemble members within each model. These experiments confirmed that the inclusion of time-varying external forcings brought simulations into closer agreement with observations. Additionally, they illustrated that the magnitude …

Maintenance Of Polish Language And Culture Among First Generation Polish Immigrants Living In The Southern San Francisco Bay Area, California., Dominika Bialek

Master's Theses

The focus of this thesis research is to investigate the extent to which first

generation Polish immigrants living in the southern San Francisco Bay Area in California maintain their native Polish language and culture. Qualitative data were collected in the form of interviews and survey questionnaires. The major findings show that in this small immigrant community (1) maintenance of Polish language and culture happens primarily at home; (2) females married to first generation Polish immigrants are more likely than others to maintain Polish language and culture; (3) the small size of the Polish community, knowledge of English at the time …

Dynamics Of Vibrio With Virulence Genes Detected In Pacific Harbor Seals (Phoca Vitulina Richardii) Off California: Implications For Marine Mammal Health, Stephanie Nichole Hughes

Master's Theses

Given their coastal site fidelity and opportunistic foraging behavior, harbor seals (Phoca vitulina) may serve as sentinels for coastal ecosystem health. Seals using urbanized coastal habitat can acquire enteric bacteria, including Vibrio, that may affect their health. To understand Vibrio dynamics in seals, demographic and environmental factors were tested for predicting potentially virulent Vibrio in free-ranging and stranded Pacific harbor seals (P. v. richardii) off the coast of California. Vibrio prevalence did not vary with season and was greater in free-ranging seals (29%, n = 319) compared with stranded seals (17%, n = 189). Of …

Utilization Of Protein Tertiary Contacts To Improve Protein Structure Prediction Using Sequence Homology, Trung Thanh Nguyen

Master's Theses

The structure of a protein ultimately determines its function; therefore, knowledge of three-dimensional structure is essential for understanding its function and mechanism of action. The two most common methods for determining protein structure are x-ray crystallography and Nuclear Magnetic Resonance (NMR) spectroscopy. These methods are quite successful but can be very time-intensive and costly. An alternative method is protein structure prediction, where structure is computationally predicted from amino acid sequence. As opposed to x-ray crystallography and NMR spectroscopy, protein structure prediction is not encumbered by potential experimental problems. In this research, we attempted to determine if certain protein structure features, …

Classical Models Of The Spin 1/2 System, Carlos Harold Salazar-Lazaro

Master's Theses

We proposed a Quaternionic mechanical system motivated by the Foucault

pendulum as a classical model for the dynamics of the spin 1/2 system. We showed

that this mechanical system contains the dynamics of the spin state of the electron

under a uniform magnetic field as it is given by the Schrodinger-Pauli-Equation

(SPE). We closed with a characterization of the dynamics of this generalized

classical system by showing that it is equivalent with the dynamics of the

Schrodinger Pauli Equation as long as the solutions to the generalized classical

system are roots of the Lagrangian, that is the condition L = …

Profiling Flavonoid Cytotoxicity In Human Breast Cancer Cell Lines, Sina Yadegarynia

Master's Theses

Flavonoids are part of a large family of polyphenols that are found extensively in fruits and vegetables. This class of compounds has been of considerable medical interest due to their anti-inflammatory and anti-cancer activities. Although extensive effort has been made to identify the biological effects responsible for the chemopreventive activity of these compounds, the exact molecular mechanisms involved are not fully understood. In this study, we focused on the cytotoxic effects of fourteen different flavonoids against a series of breast cancer cell lines and evaluated the induction of cell cycle arrest at G1 or G2/M phase as result of such …

Temporal Dynamics Of Galapagos Marine Iguna (Amblyhynchus Cristatus) Haulout, Brianna Gale Payne

Master's Theses

Galápagos marine iguanas (Amblyrhynchus cristatus) briefly forage in marine habitats but spend their remaining time hauled out on land. A wide range of diurnal activities, from social and thermoregulatory behaviors to sleep and food processing, occurs during haulout. To understand the dynamics of haulout and foraging in relation to environmental factors, I fit compartmental models derived from ordinary differential equations to field data collected daily from 30 April to 16 May 2011 at two sites—one Sandy and one Rocky—at Cabo Douglas, Isla Fernandina. The best model for haulout at the Sandy site accounts for 77–80% of observed variability and includes …

Protology And Eschatology In The Writings Of John C. Polkinghorne: A Study Of Contrastive Roles Of Scripture, H. Nicholas De Lima

Master's Theses

Problem The focus of this thesis is to address the problem of the contrastive roles of Scripture in protology and eschatology in the writings of John C. Polkinghorne. On the one hand, Polkinghorne rejects a univocal understanding of Gen 1-2, by invoking symbolic/analogical language for Gen 1-2, so that he can accept scientific protology. On the other hand, Polkinghorne introduces an apparent, relative univocity of biblical language in order to obtain his eschatology, contrary to the claims of pure scientific eschatology. This seems to suggest a dimension of internal methodological and theological incoherence in his system. Methodology This thesis provides …

Automatic Document Classification In Small Environments, Jonathan David Mcelroy

Master's Theses

Document classification is used to sort and label documents. This gives users quicker access to relevant data. Users that work with large inflow of documents spend time filing and categorizing them to allow for easier procurement. The Automatic Classification and Document Filing (ACDF) system proposed here is designed to allow users working with files or documents to rely on the system to classify and store them with little manual attention. By using a system built on Hidden Markov Models, the documents in a smaller desktop environment are categorized with better results than the traditional Naive Bayes implementation of classification.

Evaluation Of The Performance Of Non-Covalent Molecular Mechanical Models For Zn2+ And Mg2+ Metal Ions, Maria Magdalena Kamm

Master's Theses

Computer simulations using molecular dynamics (MD) on classical molecular mechanical

(MM) interatomic potentials can provide valuable information and quantitative

predictions about these systems. In MD calculations binding free energies of ions to

host molecules can be studied if correct ion solvation free energies in aqueous solution

are obtained. However, no MM models exist that parametrize various Zn2+ and

transition metals consistently and consider both structural and thermodynamic data

simultaneously.

The first part of our work focused on MD free energy perturbation (FEP) simulations

to derive MM interaction parameters for Zn2+ and Mg2+ ions in aqueous

solution. To obtain these parameters …

An Analysis Of Barriers To And Strategies For Improving Parent Engagement, Candice Renee Shakur

Master's Theses

Research shows that parent engagement can be a useful tool for improving student achievement. But, in many low-income urban schools, encouraging schools and parents to invest in parent engagement is a struggle. This paper explores some of the barriers that exist in low-income urban communities that work to limit parent engagement; it also identifies some of the strategies available to increase the frequency and quality of parent engagement in low-income urban communities.

Evolution Of Interactomes, Monica Micek

Master's Theses

Protein-protein interactions are part of all biological processes and are responsible for directing the development and maintenance of all systems in a species. Identifying such interactions provides insight into molecular processes in addition to their importance in understanding disease. Identifying protein-protein interactions experimentally is expensive, both in terms of cost and effort, and can generate erroneous results. Thus computational methods are key in reducing the scope of experimental assays, providing predictions for subsequent verification. Herein I present a new computational tool for the prediction of protein-protein interactions which, looking at sequence data alone, can identify putative interacting proteins as a …

Team Performance On A Computerized Intellective Task, Joseph Bihary

Master's Theses

This study examined the effects of a reflexivity manipulation on the performance of dyads and triads working on an intellective task known as letters-to-numbers. Past research has shown triads consistently outperforming dyads on this task. The current study sought to determine whether giving dyads an opportunity to reflect on strategy would close this gap in performance. Participants performed a computerized version of two letters-to-numbers problems in dyads or triads. Between problems, half of the groups performed a reflexivity task designed to facilitate strategy improvements. Experimental sessions were videotaped. It was predicted that triads would outperform dyads, reflexivity groups would outperform …

Computational Modeling For Transportation Network Security, Sherif A. Tolba

Master's Theses

No abstract provided.

Dynamic Test Scheduling In Hardware-In-The-Loop Simulation Of Commercial Vehicles, Tenil Cletus

Master's Theses

Modern day commercial vehicles are controlled by various Electronic Control Units (ECU). They are not only tested as single units, but also by networking them in Controlled Area Network bus (CAN) to form a complete electrical control system. This is achieved using Hardware In the Loop (HIL) Integration Lab. In HIL, the electrical system is connected to a real time mathematical model of the vehicle plus it’s environment so as to form a loop.

Testing functionality of the electrical system begins by defining functional tests. An example would be testing cruise control activation. Executing each test is made possible by …

Collisional Reactivation Of Rift Margin Fracture Zones, Taiwan And The Taconic Allochthon, David C. Mirakian

Master's Theses

Chapter I. Transverse Topographic Development due to the Reactivation of a Partially-Subducted Fracture Zone: The Southwest Hsüehshan Range, Central Taiwan

Abstract — The southwest flank of the Hsüehshan Range is defined by a topographic break which cuts across regionally mapped structures in central Taiwan. The mountain front trends ~345°, slightly oblique to the Sanyi-Puli seismic zone which has been previously interpreted as a reactivated continental margin fracture zone. Structural data collected along the length of the topographic break reveal two populations of cross-cutting faults with distinct fault-zone materials and a series of southwest-plunging folds. Paleostress axes were reconstructed using the …

Testing The Limits Of Hyperspectral Airborne Remote Sensing By Mapping Eelgrass In Elkhorn Slough, Kelley J. Bostrom

Master's Theses

Seagrass ecosystems are a valuable resource, but vulnerable to changing conditions in the coastal ocean. Quantification of seagrass density and distribution from aerial imagery can be applied as a tool in resource management and ecosystem health and stability monitoring. This study investigates analytical methods for mapping eelgrass beds in an optically complex shallow, turbid estuary. Hyperspectral imagery (HSI) of Elkhorn Slough, CA was collected by the Spectroscopic Aerial Mapper with Onboard Navigation (SAMSON) instrument. In-situ data of water column and benthic optical properties and Hydrolight Radiative Transfer model were used to create a spectral library describing the reflectance of Elkhorn …

The Limitations Of Girls’ Formal Education In Benin, Emily Elshaw

Master's Theses

This thesis explores the challenges facing Beninese women and girls in their pursuit of formal education, as well as the factors supporting their endeavors. It examines the results of interviews performed with Beninese women from varying socioeconomic backgrounds and addresses the issue of access to formal education from their point of view as well. The study findings point to the multi-faceted nature of this problem, which is rooted in various aspects of underdevelopment including misogynistic abuse, poverty, unemployment and misplaced family priorities as well as misallocation of public funds and poor classroom evaluation. It contributes to an existing body of …

Implementation Of Medicinal Leech Preparation To Investigate The Connection Between The Motor Neuron And Muscle Fiber Via Sharp Electrode Electrophysiology, Chandra Nikole Miller

Master's Theses

There are forty registered organophosphates in the United States and they range from pesticides and insecticides to nerve agents or neurotoxins such as sarin. Organophosphates (OP’s) have been used in chemical warfare for years and tend to lead to death due to an attack on the nervous system. Chemical assays and mass microscopy have been used to assess the concentration of OP’s in the environment, but both methods require the body to metabolize the OP first, which can be detrimental to the victim. It is crucial to come up with a method to investigate and detect these neurotoxins without causing …

Simulated Effects Of Varied Landscape-Scale Fuel Treatments On Carbon Dynamics And Fire Behavior In The Klamath Mountains Of California, Kevin J. Osborne

Master's Theses

I utilized forest growth model (FVS-FFE) and fire simulation software (FlamMap, Randig), integrated through GIS software (ArcMap9.3), to quantify the impacts varied landscape-scale fuel treatments have on short-term onsite carbon loss, long-term onsite carbon storage, burn probability, conditional flame length, and mean fire size. Thirteen fuel treatment scenarios were simulated on a 42,000 hectare landscape in northern California: one untreated, three proposed by the US Forest Service, and nine that were spatially-optimized and developed with the Treatment Optimization Model in FlamMap. The nine scenarios developed in FlamMap varied by treatment intensity (10%, 20%, and 30% of the landscape treated) and …

Adhesion And Durability Of Coatings On Polypropylene Exterior Sidings, Logan Riekio Stark

Master's Theses

Plastics have become a universal material for use in a myriad of commercial and consumer products. One such product, exterior siding, is the focus of this project. Although siding products were originally made from wood, vinyl siding, which offered superior performance, was introduced in the 1950’s. More recently, polypropylene (PP) siding has been introduced; PP provides a stronger product, which allows for deeper patterns and better edge detailing. PP siding, compared to traditional wood siding, doesn’t warp, crack, or degrade as easily with extended exposure to the elements, and is cheaper to maintain. However, even plastic siding must be coated. …